The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "lysosomal lumen", "input_participant_list": [ "R-ALL-2090033" ], "output_participant_list": [ "R-ALL-1678617" ], "enzyme_list": [ "E1BDR2-1" ], "evidence": [ { "id": "R-BTA-1678716", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1678716" } ] }, { "id": "R-BTA-1793186", "name": "IDUA hydrolyses the unsulfated alpha-L-iduronosidic link in DS", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "lysosomal lumen", "input_participant_list": [ "R-ALL-2105025" ], "output_participant_list": [ "R-ALL-2104993" ], "enzyme_list": [ "E1BDR2-1" ], "evidence": [ { "id": "R-BTA-1793186", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1793186" } ] }, { "id": "R-BTA-2090037", "name": "IDUA hydrolyses Heparan sulfate chain(6)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "lysosomal lumen", "input_participant_list": [ "R-ALL-2090055" ], "output_participant_list": [], "enzyme_list": [ "E1BDR2-1" ], "evidence": [ { "id": "R-BTA-2090037", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2090037" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1678617", "participant_name": "aldehydo-L-iduronic acid [lysosomal lumen]", "crossref": [ { "id": "21338", "database": "ChEBI", "url": "" }, { "id": "ZINC000100054060", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-2090033", "participant_name": "IdoA-GlcN6S-IdoA2S-GlcN3S- group [lysosomal lumen]", "crossref": [ { "id": "747403", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-2090055", "participant_name": "IdoA-GlcNS3S- group [lysosomal lumen]", "crossref": [ { "id": "63809", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-2104993", "participant_name": "CHEBI:63868 chain [lysosomal lumen]", "crossref": [ { "id": "63868", "database": "ChEBI", "url": "" }, { "id": "ZINC000263614962", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-2105025", "participant_name": "IdoA-GalNAc(4S)-GlcA-Gal-Gal-Xyl [lysosomal lumen]", "crossref": [ { "id": "63873", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "E1BDR2", "gene_name": "IDUA", "activity": [ { "ec_number": "3.2.1.76", "activity": "Hydrolysis of unsulfated alpha-L-iduronosidic linkages in dermatan sulfate.", "evidence": [ { "id": "E1BDR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDR2" } ] }, { "ec_number": "3.2.1.76", "activity": "", "evidence": [ { "id": "E1BDR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDR2" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BDR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDR2" }, { "id": "PF21200", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21200" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-L-iduronidase C-terminal", "eco_id": "ECO_0000259", "start_pos": 551, "end_pos": 639, "start_aa": "Thr", "end_aa": "Glu", "glycosite_overlap": [] }, { "evidence": [ { "id": "E1BDR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDR2" }, { "id": "PF01229", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01229" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycosyl hydrolases family 39 N-terminal catalytic", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 524, "start_aa": "His", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.2.1.76", "ec_name": "Hydrolysis of unsulfated alpha-L-iduronosidic linkages in dermatan sulfate.", "evidence": [ { "id": "3.2.1.76", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.2.1.76" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 }, { "start_pos": 189, "end_pos": 191 }, { "start_pos": 242, "end_pos": 244 }, { "start_pos": 335, "end_pos": 337 }, { "start_pos": 371, "end_pos": 373 }, { "start_pos": 414, "end_pos": 416 }, { "start_pos": 450, "end_pos": 452 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"XP_003586376", "name": "peroxisome proliferator-activated receptor gamma coactivator 1-beta isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586376" }, "gene_names": [ { "name": "PPARGC1B", "type": "recommended", "evidence": [ { "id": "E1BG53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG53" } ] }, { "name": "PPARGC1B", "type": "synonym", "evidence": [ { "id": "XP_003586376", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586376" } ] } ], "protein_names": [ { "name": "PPARG coactivator 1 beta", "type": "synonym", "evidence": [ { "id": "E1BG53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG53/entry#names_and_taxonomy" } ] }, { "name": "peroxisome proliferator-activated receptor gamma coactivator 1-beta isoform X2", "type": "synonym", "evidence": [ { "id": "XP_003586376", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586376" } ] } ], "function": [], 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"https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12356", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "514750", "url": "https://www.ncbi.nlm.nih.gov/gene/514750", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034177", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034177", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034605", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034605", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:514750", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514750", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1NBQ2", "url": "https://www.orthodb.org/?gene=A0A3Q1NBQ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15528", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15528", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15528:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15528:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9841922", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9841922", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003586376", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586376", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1NBQ2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NBQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S984", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S984", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S984-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S984-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SB60", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SB60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SB60-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SB60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BG53", "url": "https://www.uniprot.org/uniprotkb/E1BG53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BG53-1", "url": "https://www.uniprot.org/uniprotkb/E1BG53-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGNDCGSLLDEELSSFFLNYLADTQGGGSGEEQLCADFPELDLSQLDANDFDSATCFEELQWCPENSETDPSEYSPDDLELFQIIDSENEALLAALTKTLDDMPEDVVSLAALPALDDGDTPSCASASPIPSSAPPSPSLEGPPASAPEVDELSLLQKLLLATSYPTSASDSQKEGTAWRQAGLRSRNQRPCVKMDGPQDRKAPTPHPQSRSCTELHKHLTSAPSCPRAKALSPDRALQPPPSLSPRLPTKEDEEAGEDCPSPQLAPASPGDSPALGRTDPSAQVSQEDMQAMVQLIRYMHTYCLPQRKLPTQAPEPAPQPSSSPAKQVRPRPRSQHPSKAAWTEFSILRELLAQDVLCDVSKPYRLATPVYASLTPRPRPKDSQASAGHPGLVEEVRVSPSSKSSGPRPSLRPLRLQVKGHVSRSARLQPEEEEEEEEEEEEEEKEEEDEEEWGRKRPGRGLPWTKLGRKPESSVCPVRRSRRLNPELGPWLTFTDEPMVPAEPQGPLPSRLAPEAYDVEGEPGSPTDEDSGQDQLLLRGPQIPALESPCESGCGDTDEDPSCLRLSSRDSPRCLMLALSQSPTGDPPFGKKSFEQTLAVELCGTAGLTPPTTPPYKPTEEDPFKPDIKHSPGKDRAPTPEGPQLGATAEAAHKLPKKHPERSELLSHLRHTPAQPASQAGQKRPFSCSFGDHDYCQVLKPDGALQRKVLRSWEPSGAHLKDWPQPGAPRAEAQAAGREEDGSCDVGAPTKDSTLLRDHEIRASLTKHFGLLETALEDEDLASCKSPEYDTVFEDSSSSSSESTFLLEEEEDDDDEEEDSGVSPPRSDHCPYQSPPSKASRRLCPRSRSSSGSSSCRSRSPATRRNFRCESRGSCSDGTPSVRHARKRREKAIGEGRVVYVRNLSSDMSSRELKRRFEVFGEIVECQVLTRSKRGEKYGFITYRSSEHAALSLRNGTALRKRSEPSFQLSYGGLRHFCWPRYTDYDSNSEEALPASVKTKYEAMDFDSLLKEAQQSLH", "length": 1020, "header": "tr|E1BG53-1|E1BG53_BOVIN Isoform 1 of PPARG coactivator 1 beta OS=Bos taurus OX=9913 GN=PPARGC1B PE=4 SV=3 CANONICAL=E1BG53-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1NBQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBQ2/entry", "sequence": { "sequence": "MRWGQRETVFFLGAFKMWGLHPFALHRSSPEGGGSGEEQLCADFPELDLSQLDANDFDSATCFEELQWCPENSETDPSEYSPDDLELFQKCLWSSVCVSDTAFNSGLYGLEGRLTLDQIIDSENEALLAALTKTLDDMPEDVVSLAALPALDDGDTPSCASASPIPSSAPPSPSLEGPPASAPEVDELSLLQKLLLATSYPTSASDSQKEGTAWRQAGLRSRNQRPCVKMDGPQDRKAPTPHPQSRSCTELHKHLTSAPSCPRAKALSPDRALQPPPSLSPRLPTKEDEEAGEDCPSPQLAPASPGDSPALGRTDPSAQVSQEDMQAMVQLIRYMHTYCLPQRKLPTQAPEPAPQPSSSPAKQVRPRPRSQHPSKAAWTEFSILRELLAQDVLCDVSKPYRLATPVYASLTPRPRPKDSQASAGHPGLVEEVRVSPSSKSSGPRPSLRPLRLQVKGHVSRSARLQPEEEEEEEEEEEEEEKEEEDEEEWGRKRPGRGLPWTKLGRKPESSVCPVRRSRRLNPELGPWLTFTDEPMVPAEPQGPLPSRLAPEAYDVEGEPGSPTDEDSGQDQLLLRGPQIPALESPCESGCGDTDEDPSCLRLSSRDSPRCLMLALSQSPTGDPPFGKKSFEQTLAVELCGTAGLTPPTTPPYKPTEEDPFKPDIKHSPGKDRAPTPEGPQLGATAEAAHKLPKKHPERSELLSHLRHTPAQPASQAGQKRPFSCSFGDHDYCQVLKPDGALQRKVLRSWEPSGAHLKDWPQPGAPRAEAQAAGREEDGSCDVGAPTKDSTLLRDHEIRASLTKHFGLLETALEDEDLASCKSPEYDTVFEDSSSSSSESTFLLEEEEDDDDEEEDSGVSPPRSDHCPYQSPPSKASRRLCPRSRSSSGSSSCRSRSPATRRNFRCESRGSCSDGTPSVRHARKRREKAIGEGRVVYVRNLSSDMSSRELKRRFEVFGEIVECQVLTRSKRGEKYGFITYRSSEHAALSLRNGTALRKRSEPSFQLSYGGLRHFCWPRYTDYDSNSEEALPASVKTKYEAMDFDSLLKEAQQSLH", "length": 1054, "header": "tr|A0A3Q1NBQ2-1|A0A3Q1NBQ2_BOVIN Computationally mapped isoform of PPARG coactivator 1 beta OS=Bos taurus OX=9913 GN=PPARGC1B PE=4 SV=2 CANONICAL=E1BG53-1" }, "locus": { "chromosome": "7", "start_pos": 61186878, "end_pos": 61131452, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068740.3", "url": "https://www.ensembl.org/id/ENSBTAT00000068740.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068774.2", "url": "https://www.ensembl.org/id/ENSBTAP00000068774.2" } ] } }, { "isoform_ac": "A0AAA9S984-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S984/entry", "sequence": { "sequence": 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"length": 1020, "header": "tr|E1BG53-1|E1BG53_BOVIN Isoform 1 of PPARG coactivator 1 beta OS=Bos taurus OX=9913 GN=PPARGC1B PE=4 SV=3 CANONICAL=E1BG53-1" }, "locus": { "chromosome": "7", "start_pos": 61186878, "end_pos": 61073754, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017197.8", "url": "https://www.ensembl.org/id/ENSBTAT00000017197.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017197.6", "url": "https://www.ensembl.org/id/ENSBTAP00000017197.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 641, "start_aa": "Thr", "end_pos": 641, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr641", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 881, "start_aa": "Thr", "end_pos": 881, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr881", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:514750", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514750", "resource": "KEGG Pathway" }, { "id": "R-BTA-9841922", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9841922", "resource": "Reactome", "description": "MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "E1BG53", "url": "https://www.uniprot.org/uniprotkb/E1BG53" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "E1BG53", "url": "https://www.uniprot.org/uniprotkb/E1BG53" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "E1BG53", "url": 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"MAGPAGDWPEAGAATSVRSALGGYRAYARRWVFLLVISLLSCSNATLWLSFAPVADTIARHFLLSTEQINWLSLVYLVVSIPFGMVAIWVLDSVGLRRATTLGAFLNFWGSMIRSMPCMAVDIQDPFVFLLGGQTFCALAQTLVIFSPAKLAALWFPEHQRATANMIGTMSNALGILVANLLSPALVKTEEDIPLMLGTYILPAGLTFLLAIACLWESVPPTPPSVGAAQSTSLSFLAGLKLLTRNKAYMVLAVCFGGGIGIFSNFSALLEQVLCVNGYSSEFAGLCGALFIVFGVLGAVALGLYVDRTKHFTEAIKIGLCLTSLACVAFAVVSQLQGQTIVLAAICSLLGFFGFSVAPVAMELAVECSFPVGEGAAAGLVFVLGQAEGVLIMVLLTSLTVRHAEPSVSTCQDGQGPLDWKVPMLLMAGLCVLFSCLFVLLFHTPYRRLQAEADASPSIQEDERPATAAALGHAPYLAATP", "length": 481, "header": "tr|E1BDD8-1|E1BDD8_BOVIN Isoform 1 of Solute carrier family 49 member 3 OS=Bos taurus OX=9913 GN=SLC49A3 PE=4 SV=3 CANONICAL=E1BDD8-1" }, "isoforms": [ { "isoform_ac": "E1BDD8-1", "url": "https://www.uniprot.org/uniprotkb/E1BDD8/entry", "sequence": { "sequence": "MAGPAGDWPEAGAATSVRSALGGYRAYARRWVFLLVISLLSCSNATLWLSFAPVADTIARHFLLSTEQINWLSLVYLVVSIPFGMVAIWVLDSVGLRRATTLGAFLNFWGSMIRSMPCMAVDIQDPFVFLLGGQTFCALAQTLVIFSPAKLAALWFPEHQRATANMIGTMSNALGILVANLLSPALVKTEEDIPLMLGTYILPAGLTFLLAIACLWESVPPTPPSVGAAQSTSLSFLAGLKLLTRNKAYMVLAVCFGGGIGIFSNFSALLEQVLCVNGYSSEFAGLCGALFIVFGVLGAVALGLYVDRTKHFTEAIKIGLCLTSLACVAFAVVSQLQGQTIVLAAICSLLGFFGFSVAPVAMELAVECSFPVGEGAAAGLVFVLGQAEGVLIMVLLTSLTVRHAEPSVSTCQDGQGPLDWKVPMLLMAGLCVLFSCLFVLLFHTPYRRLQAEADASPSIQEDERPATAAALGHAPYLAATP", "length": 481, "header": "tr|E1BDD8-1|E1BDD8_BOVIN Isoform 1 of Solute carrier family 49 member 3 OS=Bos taurus OX=9913 GN=SLC49A3 PE=4 SV=3 CANONICAL=E1BDD8-1" }, "locus": { "chromosome": "6", "start_pos": 117647354, "end_pos": 117639869, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000044721.6", "url": "https://www.ensembl.org/id/ENSBTAT00000044721.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000042192.4", "url": "https://www.ensembl.org/id/ENSBTAP00000042192.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 222, "start_aa": "Thr", "end_pos": 222, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr222", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A480SGG9-1", "protein_name": "Solute carrier family 49 member 3", "gene_name": "SLC49A3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGLAGDNPGAAGPLTLSALRGYRAYARRWVFLLVISLLSCSNAMLWLSFAPVADTIAQHFGLSTEQINWLSLVYLVASIPFGVVAVWVLDSVGLRWAILLSAWLNFAGSVIRSLPCMLTSIHDPFAFLLGGQSLCALAQTLVIFSPAKLAALWFPEHQRATANMIGTMSNPLGLLVANLLSPALVKKEEDIPVMLGIYTIPAGLAFLLATACLWESAPPTPPSAGAAHSTSEKFLDGLKLLARNKAYIILAVCFGGGIGIFSSFSALLEQVLCVNGYSDEFAGLCGALFIVFGVLGALALGLYVDRTKHFTGAIKIGLCLTSLVCVAFALVSQLQGQTVALAAICSLFGFFGFAVAPVAMELAVECSFPVGEGAAAGLLFVLGQAEGVLIMMLLAALTVRRAEPSFSTCQDGQDPLDWKVSMLLMAGLCVLFSCLMVLFFHTPYRRLQAEADANPSIQEDTCPATSDPSDHAPHPAATL", "length": 480 }, "evidence": [ { "id": "E1BDD8", "url": "https://omabrowser.org/oma/group/E1BDD8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZU10-1", "protein_name": "Solute carrier family 49 member 3", "gene_name": "Slc49a3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARTMDRLEACNSPGTSGTPGDALPGPRVYARRWVFLLVVSLLSCSNAMLWLTFAPVADTIAQHFSLSMDQINWLSLIYLVLSIPFGMAAIWVLDSVGLRGATILGAWLNFSGSLLRAVPCLAVRIPSPFAFFMSGQSLCALAQTLVISSPAKLAALWFPEHQRATANMIGTMSNPLGILIANVLSPALVKKAEDIPMMLGIYIVPAALACLLATVCLWESVPPTPPSAGAASSTSESFLHGLKLLMKNKAYVILAVCFGGGIGVFSSFSALLEQIFCANGYSNEFSGLCGALFIVFGILGALLLGLYVDRTKHFTEATKIGLCLTSLTFVAFALVSQLQGQTFALAAICSLLGLFGFSVAPVVMELAVECSFPVGEGASAGLIFVLGQAEGVLIMLLLTAVTVRRTGPSFSTCRQGEDPLDWTVSLLLLAGLCTLFTCVLVIFFNTPYRRLEAESGGSSSPMMCAGDPRNESPTQVAPLETPGLTPPDDALQEAPGPASVSKGHSEWTETITRNV", "length": 516 }, "evidence": [ { "id": "E1BDD8", "url": "https://omabrowser.org/oma/group/E1BDD8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1ND71-1", "protein_name": "Solute carrier family 49 member 3", "gene_name": "MFSD7", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEGGESAGLLAERGPSQLKTYRRRWFLLAVVCLLNCSNAMLWLTFAPVADQTAAYFHISLEMVNWLSIVYLLISIPFGLVATWVLDSVGLRCAVILSAWLNMMGSIIRMFSVLKFMSLGSQNYWYLFVGQCLCALAQPLVIFSPTKLAALWFPDHQRATANMISSMSNPLGILIANLLSPALVPEGRHIPLMLGVYAIPALTACVLATVGIREKVPPTPPSASATNSTSQPFFMGLKMLLRNKPYIILALCFGGGIGMFTCFSALLEQILCEKGYSNVFAGLNGALFTVCGLLGAFLLGLYVDRTRNFIESTKICFCLSALASIVFAVASRFRDQAIALAITSSIFGFFGFAMYPVAMELAVECSYPVGEGTSTGLIFVASQIEGVVFMVLLQALTVRVSKDPSSTCALDQDGALDWTTPVLLMAGLCSAMACFYVIFFHTDYKRLHAETNMVKAEDTGSDDVPEA", "length": 466 }, "evidence": [ { "id": "E1BDD8", "url": "https://omabrowser.org/oma/group/E1BDD8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q6UXD7-1", "protein_name": "Solute carrier family 49 member A3", "gene_name": "SLC49A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGPTEAETGLAEPRALCAQRGHRTYARRWVFLLAISLLNCSNATLWLSFAPVADVIAEDLVLSMEQINWLSLVYLVVSTPFGVAAIWILDSVGLRAATILGAWLNFAGSVLRMVPCMVVGTQNPFAFLMGGQSLCALAQSLVIFSPAKLAALWFPEHQRATANMLATMSNPLGVLVANVLSPVLVKKGEDIPLMLGVYTIPAGVVCLLSTICLWESVPPTPPSAGAASSTSEKFLDGLKLQLMWNKAYVILAVCLGGMIGISASFSALLEQILCASGHSSGFSGLCGALFITFGILGALALGPYVDRTKHFTEATKIGLCLFSLACVPFALVSQLQGQTLALAATCSLLGLFGFSVGPVAMELAVECSFPVGEGAATGMIFVLGQAEGILIMLAMTALTVRRSEPSLSTCQQGEDPLDWTVSLLLMAGLCTFFSCILAVFFHTPYRRLQAESGEPPSTRNAVGGADSGPGVDRGGAGRAGVLGPSTATPECTARGASLEDPRGPGSPHPACHRATPRAQGPAATDAPSRPGRLAGRVQASRFIDPAGSHSSFSSPWVIT", "length": 560 }, "evidence": [ { "id": "E1BDD8", "url": "https://omabrowser.org/oma/group/E1BDD8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CE47-1", "protein_name": "Solute carrier family 49 member A3", "gene_name": "Slc49a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGTMDRLEDCNSPETSGTAGDALPSPRVYARRWVFLLVVSLLSCSNAMLWLSFAPVADTIAQHFFLSMDQVNWLSLIYFVLSIPFGMAAIWVLDSVGLRGATILGAWLNFSGSVLRAVPCLPVRIPSPFAFFMSGQSLCALAQTLVVSSPAKLAALWFPEHQRATANMISTMSNPLGLLIANVLSPALVKKADDIPMMLGIYIGPAALACLLATVCLWESVPPTPPSTGAANSTSESFLRGLKLLIQNKAYVLLAVCFGGGIGVFSSFSALLEQILCASGYSNEFSGLCGALFIVFGILGALLLGLYVDRTKHFTEATKIGLCLTSMTSVAFALVSQLQGQTLALAAICSLFGLFGFSVAPVVMELAVECSFPVGEGASAGLIFVLGQAEGMLIMLLLTALTVRRTGPSFSTCQQGEDPLDWTVSLLLLAGLCTLFTCVLVIFFNTPYRRLEAESGGSSSPTMCARDPRTVSPTQVPPLETPGLTPPDEALKEAPGPASVSKGHSEWAETMPRDV", "length": 516 }, "evidence": [ { "id": "E1BDD8", "url": "https://omabrowser.org/oma/group/E1BDD8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BDD8", "url": "https://www.uniprot.org/uniprotkb/E1BDD8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "E1BDD8", "url": "https://www.uniprot.org/uniprotkb/E1BDD8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BDD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDD8" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 447, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 222 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 265, "end_pos": 267 }, { "start_pos": 44, "end_pos": 46 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BDU5-1", "uniprot_ac": "E1BDU5", "uniprot_id": "E1BDU5_BOVIN", "mass": { "chemical_mass": 30642.0, "monoisotopic_mass": 30642.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "E1BDU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDU5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BDU5", "url": "https://www.uniprot.org/uniprotkb/E1BDU5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/E1BDU5", "locus": {} } ], "crossref": [ { "id": "E1BDU5", "url": "https://alphafold.ebi.ac.uk/entry/E1BDU5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000022922", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000022922", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050657", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050657", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24147", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24147", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24147:SF62", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24147:SF62", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BDU5", "url": "https://www.uniprot.org/uniprotkb/E1BDU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BDU5-1", "url": "https://www.uniprot.org/uniprotkb/E1BDU5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVEFLVKKEADIHAVDKMKRTALILAVNYECTDVVSLLLQRGADVFSQDVFGRTAEEYAAISGFNIICELISEYKEKRPKTTPQKSNPAAKSSEEDSLSRFSNKPGVDSWPTSDDDVLGSETKKKPKPNLAKLMKAFQQSKRNQTEHGIVRRESTNFSENNNSDSEIEDVVETLPKPSPGVQGFSHPAFPRPDPLPKPLKTLAGLGLAKVEEEKKHKDAADESRLIHQRRSRGNNKQAFPAMENKGSDRFLIVGEKQKVCCAKTTCRMKLPRQD", "length": 274, "header": "tr|E1BDU5-1|E1BDU5_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=4 SV=3 CANONICAL=E1BDU5-1" }, "isoforms": [ { "isoform_ac": "E1BDU5-1", "url": "https://www.uniprot.org/uniprotkb/E1BDU5/entry", "sequence": { "sequence": "MVEFLVKKEADIHAVDKMKRTALILAVNYECTDVVSLLLQRGADVFSQDVFGRTAEEYAAISGFNIICELISEYKEKRPKTTPQKSNPAAKSSEEDSLSRFSNKPGVDSWPTSDDDVLGSETKKKPKPNLAKLMKAFQQSKRNQTEHGIVRRESTNFSENNNSDSEIEDVVETLPKPSPGVQGFSHPAFPRPDPLPKPLKTLAGLGLAKVEEEKKHKDAADESRLIHQRRSRGNNKQAFPAMENKGSDRFLIVGEKQKVCCAKTTCRMKLPRQD", "length": 274, "header": "tr|E1BDU5-1|E1BDU5_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=4 SV=3 CANONICAL=E1BDU5-1" }, "locus": { "chromosome": "NKLS02001524.1", "start_pos": 80845, "end_pos": 51262, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000055503.4", "url": "https://www.ensembl.org/id/ENSBTAT00000055503.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000050230.3", "url": "https://www.ensembl.org/id/ENSBTAP00000050230.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 143, "end_pos": 145 }, { "start_pos": 156, "end_pos": 158 }, { "start_pos": 161, "end_pos": 163 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BGW3-1", "uniprot_ac": "E1BGW3", "uniprot_id": "E1BGW3_BOVIN", "mass": { "chemical_mass": 57907.0, "monoisotopic_mass": 57907.0 }, "refseq": { "ac": "NP_001179133", "name": "zinc finger and BTB domain-containing protein 7B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179133" }, "gene_names": [ { "name": "ZBTB7B", "type": "recommended", "evidence": [ { "id": "E1BGW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGW3" } ] }, { "name": "ZBTB7B", "type": "synonym", "evidence": [ { "id": "NP_001179133", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179133" } ] } ], "protein_names": [ { "name": "Zinc finger and BTB domain-containing protein 7B", "type": "recommended", "evidence": [ { "id": "E1BGW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGW3/entry#names_and_taxonomy" } ] }, { "name": "Krueppel-related zinc finger protein cKrox", "type": "synonym", "evidence": [ { "id": "E1BGW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGW3/entry#names_and_taxonomy" } ] }, { "name": "T-helper-inducing POZ/Krueppel-like factor", "type": "synonym", "evidence": [ { "id": "E1BGW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGW3/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger protein Th-POK", "type": "synonym", "evidence": [ { "id": "E1BGW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGW3/entry#names_and_taxonomy" } ] }, { "name": "zinc finger and BTB domain-containing protein 7B", "type": "synonym", "evidence": [ { "id": "NP_001179133", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179133" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BGW3", "url": "https://www.uniprot.org/uniprotkb/E1BGW3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZBTB7B", "url": "https://www.uniprot.org/uniprotkb/E1BGW3", "locus": { "chromosome": "3", "start_pos": 15579983, "end_pos": 15598162, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021512", "url": "https://www.ensembl.org/id/ENSBTAG00000021512" } ] } } ], "crossref": [ { "id": "E1BGW3", "url": "https://alphafold.ebi.ac.uk/entry/E1BGW3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021512", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021512", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18327", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18327", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "509019", "url": "https://www.ncbi.nlm.nih.gov/gene/509019", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:509019", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509019", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SPEHHEL", "url": "https://omabrowser.org/oma/group/SPEHHEL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BGW3", "url": "https://www.orthodb.org/?gene=E1BGW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179133", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179133", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9RW63", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RW63-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW63-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RXE7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RXE7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXE7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SGC7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SGC7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SMJ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SMJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYW3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYW3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T1H4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1H4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T1H4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1H4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGW3", "url": "https://www.uniprot.org/uniprotkb/E1BGW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGW3-1", "url": "https://www.uniprot.org/uniprotkb/E1BGW3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSPEDDLIGIPFPDHSSELLSCLNEQRQLGHLCDLTIRTQGLEYRTHRAVLAACSHYFKKLFTEGGGGALSGAGGGGTAAGGAGAGVCELDFVGPEALGALLEFAYTATLTTSSANMPAVLQAARLLEIPCVIAACMEILQGSGLEAPSPDEDDCERARQYLEAFACTATASASGVPNGDDSPPQAPLPPPPPPPPRPVARRSRKPRKAFLQTKGARANHLVPEVPTVPTHPFTYEEEEEAGRVGSGLGDSYSPPTGAASPPEGPLSYEACEGEEEEEELVYPPPYGLAQGGGPPLSPEELGSDEDAIDPDLMAYLSSLHQDTLPPGLDSQDKLVRKRRSQMPQECPVCHKIIHGAGKLPRHMRTHTGEKPFACEVCGVRFTRNDKLKIHMRKHTGERPYSCSHCPARFLHSYDLKNHMHLHTGDRPYECHLCHKAFAKEDHLQRHLKGQNCLEVRTRRRRKDDAPPHYPPPSAATSSPAGLDLSNGHLDTFRLSLPRFWETSAPTGPPDSTPGPPDDDEEEGAPTTPQAEGAMDTS", "length": 538, "header": "tr|E1BGW3-1|E1BGW3_BOVIN Isoform 1 of Zinc finger and BTB domain-containing protein 7B OS=Bos taurus OX=9913 GN=ZBTB7B PE=4 SV=3 CANONICAL=E1BGW3-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RW63-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW63/entry", "sequence": { "sequence": "MGGKQAGGQDRSRAPSPRAWRGTRFSPHPEPQQLQPADPKAERGQEELPARPLSVQEKMGSPEDDLIGIPFPDHSSELLSCLNEQRQLGHLCDLTIRTQGLEYRTHRAVLAACSHYFKKLFTEGGGGALSGAGGGGTAAGGAGAGVCELDFVGPEALGALLEFAYTATLTTSSANMPAVLQAARLLEIPCVIAACMEILQGSGLEAPSPDEDDCERARQYLEAFACTATASASGVPNGDDSPPQAPLPPPPPPPPRPVARRSRKPRKAFLQTKGARANHLVPEVPTVPTHPFTYEEEEEAGRVGSGLGDSYSPPTGAASPPEGPLSYEACEGEEEEEELVYPPPYGLAQGGGPPLSPEELGSDEDAIDPDLMAYLSSLHQDTLPPGLDSQDKLVRKRRSQMPQECPVCHKIIHGAGKLPRHMRTHTGEKPFACEVCGVRFTRNDKLKIHMRKHTGERPYSCSHCPARFLHSYDLKNHMHLHTGDRPYECHLCHKAFAKEDHLQRHLKGQNCLEVRTRRRRKDDAPPHYPPPSAATSSPAGLDLSNGHLDTFRLSLPRFWETSAPTGPPDSTPGPPDDDEEEGAPTTPQAEGAMDTS", "length": 596, "header": "tr|A0AAA9RW63-1|A0AAA9RW63_BOVIN Computationally mapped isoform of Zinc finger and BTB domain-containing protein 7B OS=Bos taurus OX=9913 GN=ZBTB7B PE=4 SV=1 CANONICAL=E1BGW3-1" }, "locus": { "chromosome": "3", "start_pos": 15594204, "end_pos": 15580274, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118831.1", "url": "https://www.ensembl.org/id/ENSBTAT00000118831.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077656.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077656.1" } ] } }, { "isoform_ac": "A0AAA9RXE7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXE7/entry", "sequence": { "sequence": "MGGKQAGGQEKMGSPEDDLIGIPFPDHSSELLSCLNEQRQLGHLCDLTIRTQGLEYRTHRAVLAACSHYFKKLFTEGGGGALSGAGGGGTAAGGAGAGVCELDFVGPEALGALLEFAYTATLTTSSANMPAVLQAARLLEIPCVIAACMEILQGSGLEAPSPDEDDCERARQYLEAFACTATASASGVPNGDDSPPQAPLPPPPPPPPRPVARRSRKPRKAFLQTKGARANHLVPEVPTVPTHPFTYEEEEEAGRVGSGLGDSYSPPTGAASPPEGPLSYEACEGEEEEEELVYPPPYGLAQGGGPPLSPEELGSDEDAIDPDLMAYLSSLHQDTLPPGLDSQDKLVRKRRSQMPQECPVCHKIIHGAGKLPRHMRTHTGEKPFACEVCGVRFTRNDKLKIHMRKHTGERPYSCSHCPARFLHSYDLKNHMHLHTGDRPYECHLCHKAFAKEDHLQRHLKGQNCLEVRTRRRRKDDAPPHYPPPSAATSSPAGLDLSNGHLDTFRLSLPRFWETSAPTGPPDSTPGPPDDDEEEGAPTTPQAEGAMDTS", "length": 549, "header": "tr|A0AAA9RXE7-1|A0AAA9RXE7_BOVIN Computationally mapped isoform of Zinc finger and BTB domain-containing protein 7B OS=Bos taurus OX=9913 GN=ZBTB7B PE=4 SV=1 CANONICAL=E1BGW3-1" }, "locus": { "chromosome": "3", "start_pos": 15594204, "end_pos": 15580274, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123960.1", "url": "https://www.ensembl.org/id/ENSBTAT00000123960.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075872.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075872.1" } ] } }, { "isoform_ac": "A0AAA9SGC7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGC7/entry", "sequence": { "sequence": "MPPPGSFLFRCPQLPPSVHPTSGQLYPPDPPGHWGLAQVLPPGLVGRGWHPGKELWGQEELPARPLSVQEKMGSPEDDLIGIPFPDHSSELLSCLNEQRQLGHLCDLTIRTQGLEYRTHRAVLAACSHYFKKLFTEGGGGALSGAGGGGTAAGGAGAGVCELDFVGPEALGALLEFAYTATLTTSSANMPAVLQAARLLEIPCVIAACMEILQGSGLEAPSPDEDDCERARQYLEAFACTATASASGVPNGDDSPPQAPLPPPPPPPPRPVARRSRKPRKAFLQTKGARANHLVPEVPTVPTHPFTYEEEEEAGRVGSGLGDSYSPPTGAASPPEGPLSYEACEGEEEEEELVYPPPYGLAQGGGPPLSPEELGSDEDAIDPDLMAYLSSLHQDTLPPGLDSQDKLVRKRRSQMPQECPVCHKIIHGAGKLPRHMRTHTGEKPFACEVCGVRFTRNDKLKIHMRKHTGERPYSCSHCPARFLHSYDLKNHMHLHTGDRPYECHLCHKAFAKEDHLQRHLKGQNCLEVRTRRRRKDDAPPHYPPPSAATSSPAGLDLSNGHLDTFRLSLPRFWETSAPTGPPDSTPGPPDDDEEEGAPTTPQAEGAMDTS", "length": 609, "header": "tr|A0AAA9SGC7-1|A0AAA9SGC7_BOVIN Computationally mapped isoform of Zinc finger and BTB domain-containing protein 7B OS=Bos taurus OX=9913 GN=ZBTB7B PE=4 SV=1 CANONICAL=E1BGW3-1" }, "locus": { "chromosome": "3", "start_pos": 15588659, "end_pos": 15580274, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093459.1", "url": "https://www.ensembl.org/id/ENSBTAT00000093459.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082729.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082729.1" } ] } }, { "isoform_ac": "A0AAA9SMJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMJ4/entry", "sequence": { "sequence": "MERESWRWQPGGGGEKMGSPEDDLIGIPFPDHSSELLSCLNEQRQLGHLCDLTIRTQGLEYRTHRAVLAACSHYFKKLFTEGGGGALSGAGGGGTAAGGAGAGVCELDFVGPEALGALLEFAYTATLTTSSANMPAVLQAARLLEIPCVIAACMEILQGSGLEAPSPDEDDCERARQYLEAFACTATASASGVPNGDDSPPQAPLPPPPPPPPRPVARRSRKPRKAFLQTKGARANHLVPEVPTVPTHPFTYEEEEEAGRVGSGLGDSYSPPTGAASPPEGPLSYEACEGEEEEEELVYPPPYGLAQGGGPPLSPEELGSDEDAIDPDLMAYLSSLHQDTLPPGLDSQDKLVRKRRSQMPQECPVCHKIIHGAGKLPRHMRTHTGEKPFACEVCGVRFTRNDKLKIHMRKHTGERPYSCSHCPARFLHSYDLKNHMHLHTGDRPYECHLCHKAFAKEDHLQRHLKGQNCLEVRTRRRRKDDAPPHYPPPSAATSSPAGLDLSNGHLDTFRLSLPRFWETSAPTGPPDSTPGPPDDDEEEGAPTTPQAEGAMDTS", "length": 554, "header": "tr|A0AAA9SMJ4-1|A0AAA9SMJ4_BOVIN Computationally mapped isoform of Zinc finger and BTB domain-containing protein 7B OS=Bos taurus OX=9913 GN=ZBTB7B PE=4 SV=1 CANONICAL=E1BGW3-1" }, "locus": { "chromosome": "3", "start_pos": 15583172, "end_pos": 15580274, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124706.1", "url": "https://www.ensembl.org/id/ENSBTAT00000124706.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085164.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085164.1" } ] } }, { "isoform_ac": "A0AAA9SYW3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW3/entry", "sequence": { "sequence": "MLGVGRNGGSGRGLSERTKSQKKGEEKMGSPEDDLIGIPFPDHSSELLSCLNEQRQLGHLCDLTIRTQGLEYRTHRAVLAACSHYFKKLFTEGGGGALSGAGGGGTAAGGAGAGVCELDFVGPEALGALLEFAYTATLTTSSANMPAVLQAARLLEIPCVIAACMEILQGSGLEAPSPDEDDCERARQYLEAFACTATASASGVPNGDDSPPQAPLPPPPPPPPRPVARRSRKPRKAFLQTKGARANHLVPEVPTVPTHPFTYEEEEEAGRVGSGLGDSYSPPTGAASPPEGPLSYEACEGEEEEEELVYPPPYGLAQGGGPPLSPEELGSDEDAIDPDLMAYLSSLHQDTLPPGLDSQDKLVRKRRSQMPQECPVCHKIIHGAGKLPRHMRTHTGEKPFACEVCGVRFTRNDKLKIHMRKHTGERPYSCSHCPARFLHSYDLKNHMHLHTGDRPYECHLCHKAFAKEDHLQRHLKGQNCLEVRTRRRRKDDAPPHYPPPSAATSSPAGLDLSNGHLDTFRLSLPRFWETSAPTGPPDSTPGPPDDDEEEGAPTTPQAEGAMDTS", "length": 565, "header": "tr|A0AAA9SYW3-1|A0AAA9SYW3_BOVIN Computationally mapped isoform of Zinc finger and BTB domain-containing protein 7B OS=Bos taurus OX=9913 GN=ZBTB7B PE=4 SV=1 CANONICAL=E1BGW3-1" }, "locus": { "chromosome": "3", "start_pos": 15586941, "end_pos": 15580274, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124762.1", "url": "https://www.ensembl.org/id/ENSBTAT00000124762.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090568.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090568.1" } ] } }, { "isoform_ac": "A0AAA9T1H4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1H4/entry", "sequence": { "sequence": "MRRKSGLIHNRDSQLITSNMILNGVQKEKMGSPEDDLIGIPFPDHSSELLSCLNEQRQLGHLCDLTIRTQGLEYRTHRAVLAACSHYFKKLFTEGGGGALSGAGGGGTAAGGAGAGVCELDFVGPEALGALLEFAYTATLTTSSANMPAVLQAARLLEIPCVIAACMEILQGSGLEAPSPDEDDCERARQYLEAFACTATASASGVPNGDDSPPQAPLPPPPPPPPRPVARRSRKPRKAFLQTKGARANHLVPEVPTVPTHPFTYEEEEEAGRVGSGLGDSYSPPTGAASPPEGPLSYEACEGEEEEEELVYPPPYGLAQGGGPPLSPEELGSDEDAIDPDLMAYLSSLHQDTLPPGLDSQDKLVRKRRSQMPQECPVCHKIIHGAGKLPRHMRTHTGEKPFACEVCGVRFTRNDKLKIHMRKHTGERPYSCSHCPARFLHSYDLKNHMHLHTGDRPYECHLCHKAFAKEDHLQRHLKGQNCLEVRTRRRRKDDAPPHYPPPSAATSSPAGLDLSNGHLDTFRLSLPRFWETSAPTGPPDSTPGPPDDDEEEGAPTTPQAEGAMDTS", "length": 567, "header": "tr|A0AAA9T1H4-1|A0AAA9T1H4_BOVIN Computationally mapped isoform of Zinc finger and BTB domain-containing protein 7B OS=Bos taurus OX=9913 GN=ZBTB7B PE=4 SV=1 CANONICAL=E1BGW3-1" }, "locus": { "chromosome": "3", "start_pos": 15597996, "end_pos": 15580274, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000107811.1", "url": "https://www.ensembl.org/id/ENSBTAT00000107811.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089510.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089510.1" } ] } }, { "isoform_ac": "E1BGW3-1", "url": "https://www.uniprot.org/uniprotkb/E1BGW3/entry", "sequence": { "sequence": "MGSPEDDLIGIPFPDHSSELLSCLNEQRQLGHLCDLTIRTQGLEYRTHRAVLAACSHYFKKLFTEGGGGALSGAGGGGTAAGGAGAGVCELDFVGPEALGALLEFAYTATLTTSSANMPAVLQAARLLEIPCVIAACMEILQGSGLEAPSPDEDDCERARQYLEAFACTATASASGVPNGDDSPPQAPLPPPPPPPPRPVARRSRKPRKAFLQTKGARANHLVPEVPTVPTHPFTYEEEEEAGRVGSGLGDSYSPPTGAASPPEGPLSYEACEGEEEEEELVYPPPYGLAQGGGPPLSPEELGSDEDAIDPDLMAYLSSLHQDTLPPGLDSQDKLVRKRRSQMPQECPVCHKIIHGAGKLPRHMRTHTGEKPFACEVCGVRFTRNDKLKIHMRKHTGERPYSCSHCPARFLHSYDLKNHMHLHTGDRPYECHLCHKAFAKEDHLQRHLKGQNCLEVRTRRRRKDDAPPHYPPPSAATSSPAGLDLSNGHLDTFRLSLPRFWETSAPTGPPDSTPGPPDDDEEEGAPTTPQAEGAMDTS", "length": 538, "header": "tr|E1BGW3-1|E1BGW3_BOVIN Isoform 1 of Zinc finger and BTB domain-containing protein 7B OS=Bos taurus OX=9913 GN=ZBTB7B PE=4 SV=3 CANONICAL=E1BGW3-1" }, "locus": { "chromosome": "3", "start_pos": 15582251, "end_pos": 15580274, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028669.6", "url": "https://www.ensembl.org/id/ENSBTAT00000028669.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028669.5", "url": "https://www.ensembl.org/id/ENSBTAP00000028669.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 513, "start_aa": "Thr", "end_pos": 513, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr513", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:509019", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509019", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A579-1", "protein_name": "Zinc finger and BTB domain-containing protein 7B", "gene_name": "Zbtb7b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSPEDDLIGIPFPDHSSELLSCLNEQRQLGHLCDLTIRTQGLEYRTHRAVLAACSHYFKKLFTEGGGGTVMGTGGGGTAAGGAGAGVCELDFVGPEALGALLEFAYTATLTTSSANMPAVLQAARLLEIPCVIAACMEILQGSGLEAPSPDEDDCERARQYLEAFATATTTASTSGMPNGEDSPPQVPLLPPPPPPPRPVARRSRKPRKAFLQTKGARANHLVPEAPTVLTHPLAYEEEEMVGRVGNSGGSGLGDNYSPPAGATSPAEGPLNYEVFEGEEEEEELVYPPAYGLAQSNEPSLSPEELGSDEDPIDPDLMAYLSSLHQDALAPGLDGQDKLVRKRRSQMPQECPVCHKIIHGAGKLPRHMRTHTGEKPFACEVCGVRFTRNDKLKIHMRKHTGERPYSCPHCPARFLHSYDLKNHMHLHTGDRPYECHLCHKAFAKEDHLQRHLKGQNCLEVRTRRRRKDDAPPHYPPPSTTTSSPAGLDLSNGHLDTFRLSLARFWEQSATTGPPVTTQGPPEEEEEEGTPTTPQAESAMESS", "length": 543 }, "evidence": [ { "id": "E1BGW3", "url": "https://omabrowser.org/oma/group/E1BGW3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HC63-1", "protein_name": "Zinc finger and BTB domain-containing protein 7B", "gene_name": "Zbtb7b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGSPEDDLIGIPFPDHSSELLSCLNEQRQLGHLCDLTIRTQGLEYRTHRAVLAACSHYFKKLFTEGGGGAVMGTGGGGTAAGGAGAGVCELDFVGPEALGALLEFAYTATLTTSSANMPAVLQAARLLEIPCVIAACMEILQGSGLEAPSPDEDDCERARQYLEAFATATTSASTSGVPNGEDSPPQVPLLLPPPPPPRPVARRSRKPRKAFLQTKGARANHLVPEAPTVLSHPLTFEEEGMVARVGNSGGSGLGDNYSPPTSAASPPEGPLNYEVCEGEEEEEELAYPPAYGLAQSNEPSLSPEELGSDEDTIDPDLMAYLSSLHQDALAPGLDGQDKLVRKRRSQMPQECPVCHKIIHGAGKLPRHMRTHTGEKPFACEVCGVRFTRNDKLKIHMRKHTGERPYSCPHCPARFLHSYDLKNHMHLHTGDRPYECHLCHKAFAKEDHLQRHLKGQNCLEVRTRRRRKDDAPPHYPPPPTSAPSPAGLDLSNGHLDTFRLTLARFWEQSAPTGPPVTTQGPPEEEEEEGTPATPQAEGAMESS", "length": 543 }, "evidence": [ { "id": "E1BGW3", "url": "https://omabrowser.org/oma/group/E1BGW3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3L7Q9-1", "protein_name": "Zinc finger and BTB domain-containing protein 7B", "gene_name": "ZBTB7B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGSPEDDLIGIPFPDHSSELLSCLNEQRQLGHLCDLTIRTQGLEYRTHRAVLAACSHYFKKLFTEGGGGAVMGAGGGGTAPGGAGGGVCELDFVGPEALGALLEFAYTATLTTSSANMPAVLQAARLLEIPCVIAACMEILQGSGLEAPSPDEDDCERARQYLEAFATATASASAAGVPNGEESPPQVPPPPPPPPPRPVARRSRKPRKAFLQTKGARANHLVPDVPMVPAHPLTYEEEEEAAGRVGSSGGSGLGDSYSPPTGTASPPEGPLNYEAYEGEEEEEELVYPQTYGLTQGGGPPLSPEELGSDEDAIDPDLMAYLSSLHQDALAPGLDGQDKLVRKRRSQMPQECPVCHKIIHGAGKLPRHMRTHTGEKPFACEVCGVRFTRNDKLKIHMRKHTGERPYSCPHCPARFLHSYDLKNHMHLHTGDRPYECHLCHKAFAKEDHLQRHLKGQNCLEVRTRRRRKDDAPPHYPPPSAATPSPAGLDLSNGHLDNFRLSLARFWEQSAPTGPPVSTPGPPDDDEEEGAPATPQAEGAMESS", "length": 543 }, "evidence": [ { "id": "E1BGW3", "url": "https://omabrowser.org/oma/group/E1BGW3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O15156-1", "protein_name": "Zinc finger and BTB domain-containing protein 7B", "gene_name": "ZBTB7B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSPEDDLIGIPFPDHSSELLSCLNEQRQLGHLCDLTIRTQGLEYRTHRAVLAACSHYFKKLFTEGGGGAVMGAGGSGTATGGAGAGVCELDFVGPEALGALLEFAYTATLTTSSANMPAVLQAARLLEIPCVIAACMEILQGSGLEAPSPDEDDCERARQYLEAFATATASGVPNGEDSPPQVPLPPPPPPPPRPVARRSRKPRKAFLQTKGARANHLVPEVPTVPAHPLTYEEEEVAGRVGSSGGSGPGDSYSPPTGTASPPEGPQSYEPYEGEEEEEELVYPPAYGLAQGGGPPLSPEELGSDEDAIDPDLMAYLSSLHQDNLAPGLDSQDKLVRKRRSQMPQECPVCHKIIHGAGKLPRHMRTHTGEKPFACEVCGVRFTRNDKLKIHMRKHTGERPYSCPHCPARFLHSYDLKNHMHLHTGDRPYECHLCHKAFAKEDHLQRHLKGQNCLEVRTRRRRKDDAPPHYPPPSTAAASPAGLDLSNGHLDTFRLSLARFWEQSAPTGPPVSTPGPPDDDEEEGAPTTPQAEGAMESS", "length": 539 }, "evidence": [ { "id": "E1BGW3", "url": "https://omabrowser.org/oma/group/E1BGW3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q64321-1", "protein_name": "Zinc finger and BTB domain-containing protein 7B", "gene_name": "Zbtb7b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSPEDDLIGIPFPDHSSELLSCLNEQRQLGHLCDLTIRTQGLEYRTHRAVLAACSHYFKKLFTEGGGGTVMGTGGGGTASGGAGAGVCELDFVGPEALGALLEFAYTATLTTSSANMPAVLQAARLLEIPCVIAACMEILQGSGLEAPSPDEDDCERARQYLEAFATATTTASTSGMPNGEDSPPQVPLLPPPPPPPRPVARRSRKPRKAFLQTKGARANHLVPEAPTVLTHPLTYEEEEMVGRLGNSGGSGLGDSYSPPTGAASPAEGPLNYEVFEGEEEEEEMAYPPGYGLAQSNEPSLSPEELGSDEDPIDPDLMAYLSSLHQDALTPGLDGQDKLVRKRRSQMPQECPVCHKIIHGAGKLPRHMRTHTGEKPFACEVCGVRFTRNDKLKIHMRKHTGERPYSCPHCPARFLHSYDLKNHMHLHTGDRPYECHLCHKAFAKEDHLQRHLKGQNCLEVRTRRRRKDDVAAPHYPPPSTTTSSPAGLDLSNGHLDTFHLSLARFWEQSATTGPPVTTQGPPEEEEEEGTPTTPQAEGAMESS", "length": 544 }, "evidence": [ { "id": "E1BGW3", "url": "https://omabrowser.org/oma/group/E1BGW3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BGW3", "url": "https://www.uniprot.org/uniprotkb/E1BGW3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BGW3", "url": "https://www.uniprot.org/uniprotkb/E1BGW3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 17, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BGW3", "url": "https://www.uniprot.org/uniprotkb/E1BGW3" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "E1BGW3", "url": "https://www.uniprot.org/uniprotkb/E1BGW3" } ], "pmid": "" }, { "name": "positive regulation of interleukin-17 production", "id": "GO:0032740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032740", "evidence": [ { "database": "UniProtKB", "id": "E1BGW3", "url": "https://www.uniprot.org/uniprotkb/E1BGW3" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "E1BGW3", "url": "https://www.uniprot.org/uniprotkb/E1BGW3" } ], "pmid": "" }, { "name": "response to insulin", "id": "GO:0032868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032868", "evidence": [ { "database": "UniProtKB", "id": "E1BGW3", "url": "https://www.uniprot.org/uniprotkb/E1BGW3" } ], "pmid": "" }, { "name": "lactation", "id": "GO:0007595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007595", "evidence": [ { "database": "UniProtKB", "id": "E1BGW3", "url": "https://www.uniprot.org/uniprotkb/E1BGW3" } ], "pmid": "" }, { "name": "positive regulation of insulin receptor signaling pathway", "id": "GO:0046628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046628", "evidence": [ { "database": "UniProtKB", "id": "E1BGW3", "url": "https://www.uniprot.org/uniprotkb/E1BGW3" } ], "pmid": "" }, { "name": "positive regulation of brown fat cell differentiation", "id": "GO:0090336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090336", "evidence": [ { "database": "UniProtKB", "id": "E1BGW3", "url": "https://www.uniprot.org/uniprotkb/E1BGW3" } ], "pmid": "" }, { "name": "positive regulation of CD4-positive, alpha-beta T cell differentiation", "id": "GO:0043372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043372", "evidence": [ { "database": "UniProtKB", "id": "E1BGW3", "url": "https://www.uniprot.org/uniprotkb/E1BGW3" } ], "pmid": "" }, { "name": "NK T cell differentiation", "id": "GO:0001865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001865", "evidence": [ { "database": "UniProtKB", "id": "E1BGW3", "url": "https://www.uniprot.org/uniprotkb/E1BGW3" } ], "pmid": "" }, { "name": "adaptive thermogenesis", "id": "GO:1990845", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990845", "evidence": [ { "database": "UniProtKB", "id": "E1BGW3", "url": "https://www.uniprot.org/uniprotkb/E1BGW3" } ], "pmid": "" }, { "name": "positive regulation of cold-induced thermogenesis", "id": "GO:0120162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120162", "evidence": [ { "database": "UniProtKB", "id": "E1BGW3", "url": "https://www.uniprot.org/uniprotkb/E1BGW3" } ], "pmid": "" }, { "name": "negative regulation of CD8-positive, alpha-beta T cell differentiation", "id": "GO:0043377", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043377", "evidence": [ { "database": "UniProtKB", "id": "E1BGW3", "url": "https://www.uniprot.org/uniprotkb/E1BGW3" } ], "pmid": "" }, { "name": "negative regulation of NK T cell proliferation", "id": "GO:0051141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051141", "evidence": [ { "database": "UniProtKB", "id": "E1BGW3", "url": "https://www.uniprot.org/uniprotkb/E1BGW3" } ], "pmid": "" }, { "name": "positive regulation of SREBP signaling pathway", "id": "GO:2000640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000640", "evidence": [ { "database": "UniProtKB", "id": "E1BGW3", "url": "https://www.uniprot.org/uniprotkb/E1BGW3" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BGW3", "url": "https://www.uniprot.org/uniprotkb/E1BGW3" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "E1BGW3", "url": "https://www.uniprot.org/uniprotkb/E1BGW3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BGW3", "url": "https://www.uniprot.org/uniprotkb/E1BGW3" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "E1BGW3", "url": "https://www.uniprot.org/uniprotkb/E1BGW3" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "E1BGW3", "url": "https://www.uniprot.org/uniprotkb/E1BGW3" } ], "pmid": "" }, { "name": "histone deacetylase binding", "id": "GO:0042826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042826", "evidence": [ { "database": "UniProtKB", "id": "E1BGW3", "url": "https://www.uniprot.org/uniprotkb/E1BGW3" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BGW3", "url": "https://www.uniprot.org/uniprotkb/E1BGW3" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "E1BGW3", "url": "https://www.uniprot.org/uniprotkb/E1BGW3" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity", "id": "GO:0001217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001217", "evidence": [ { "database": "UniProtKB", "id": "E1BGW3", "url": "https://www.uniprot.org/uniprotkb/E1BGW3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BGW3", "url": "https://www.uniprot.org/uniprotkb/E1BGW3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], 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"CD23 is a glycan-binding receptor in some mammalian species.", "journal": "J. 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{ "name": "Golgin-97", "type": "synonym", "evidence": [ { "id": "E1BFF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFF9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Involved in vesicular trafficking at the Golgi apparatus level. Involved in endosome-to-Golgi trafficking. Mechanistically, captures transport vesicles arriving from endosomes via the protein TBC1D23. Recognized vesicles are then tethered to the trans-Golgi before subsequent SNARE engagement and vesicle fusion. 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"MLRSDTPVPQTFGLHFSGNAASLDNWAFLGTCLGIPGCWPNNCCSGQALVISVGEPHSKMFAKLKKKIAEETAVAQRPGGATRIPRSVSKESVASMGADSGDDFASDGSSSREDLSSQLLRRNEQIRKLEARLSDYAEQVRTLQKIKEKLEIALEKHQDSSMRKFQEQNETFQANRARMAEGLALALARKDQEWSEKVDQLEKDKRFLTAQLQEMKNQSLNLFQRRDEMDELEGFQQQELSKVKHMLLKKEESLGKMEQELEARTRELSRTQEELVTSSQISLDLSQKLEELQRHYSALEEQRDHVTASKTGAENKITVLEQKEQELQAFIQQLSIDLQKVTAETQEKEKLITHLQEKVASLEKRLEQNLSGEEHVQELLKEKTLAEQNLEDTRQQLLAARSSQAKAINNLETRVKELEQSLQASEEELKRSGDVVAAREAQIRELAAANTESSRAQQQALALEQQQAERIHALETQLAGLGRARVADLTATEQELRKLEQENAALKESKNECECSLQHHQLELKKLKEEWSQREIVSVAMAQALEEVRKQREELQQQAADLTAMMGEKEQSLQEKMEVILQKEQEILQLKKGHDSALLQTRQLQSELEALQGLRAEEATATREDLLRLTGQERPLVLSASKPHVTSRARQDPEYQLPAVEGIPNGEMGAATDLGQLQKEKQDLEQQLLEKNKTIKQMQQRMLELKKTLQKELKIRPDNELFEVREKPGPEMSNLAPSVTNNADLTDAREINFEYLKHVVLKFMSCRESEAFHLIKAVSVLLNFSQEEENMLKETLEYKLALKAEALSLCQEGRQPIHHVVMMLDRQAFKTVPRRADPPASAVKSQLSEAGFFQLPFPVCKFGFR", "length": 865, "header": "tr|E1BFF9-1|E1BFF9_BOVIN Isoform 1 of Golgin subfamily A member 1 OS=Bos taurus OX=9913 GN=GOLGA1 PE=4 SV=2 CANONICAL=E1BFF9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SFK8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFK8/entry", "sequence": { "sequence": "MFAKLKKKIAEETAVAQRPGGATRIPRSVSKESVASMGADSGDDFASDGSSSREDLSSQLLRRNEQIRKLEARLSDYAEQVRTLQKIKEKLEIALEKHQDSSMRKFQEQNETFQANRARMAEGLALALARKDQEWSEKVDQLEKDKRFLTAQLQEMKNQSLNLFQRRDEMDELEGFQQQELSKVKHMLLKKEESLGKMEQELEARTRELSRTQEELVTSSQISLDLSQKLEELQRHYSALEEQRDHVTASKTGAENKITVLEQKEQELQAFIQQLSIDLQKVTAETQEKEKLITHLQEKVASLEKRLEQNLSGEEHVQELLKEKTLAEQNLEDTRQQLLAARSSQAKAINNLETRVKELEQSLQASEEELKRSGDVVAAREAQIRELAAANTESSRAQQQALALEQQQAERIHALETQLAGLGRARVADLTATEQELRKLEQENAALKESKNECECSLQHHQLELKKLKEEWSQREIVSVAMAQALEEVRKQREELQQQAADLTAMMGEKEQSLQEKMEVILQKEQEILQLKKGHDSALLQTRQLQSELEALQGLRAEEATATREDLLRLTGQERPLVLSASKPHVTSRARQDPEYQLPAVEGIPNGEMGAATDLGQLQKEKQDLEQQLLEKNKKIRPDNELFEVREKPGPEMSNLAPSVTNNADLTDAREINFEYLKHVVLKFMSCRESEAFHLIKAVSVLLNFSQEEENMLKETLEYKMSWFGSKPAPKGSIRPSISNPRTPWS", "length": 746, "header": "tr|A0AAA9SFK8-1|A0AAA9SFK8_BOVIN Computationally mapped isoform of Golgin subfamily A member 1 OS=Bos taurus OX=9913 GN=GOLGA1 PE=4 SV=1 CANONICAL=E1BFF9-1" }, "locus": { "chromosome": "11", "start_pos": 95909829, "end_pos": 95869963, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000131500.1", "url": "https://www.ensembl.org/id/ENSBTAT00000131500.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084959.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084959.1" } ] } }, { "isoform_ac": "A0AAA9TRT2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRT2/entry", "sequence": { "sequence": "MLRSDTPVPQTFGLHFSGNAASLDNWAFLGTCLGIPGCWPNNCCSGQALVISVGEPHSKMFAKLKKKIAEETAVAQRPGGATRIPRSVSKESVASMGADSGDDFASDGSSSREDLSSQLLRRNEQIRKLEARLSDYAEQVRTLQKIKEKLEIALEKHQDSSMRKFQEQNETFQANRARMAEGLALALARKDQEWSEKVDQLEKDKRFLTAQLQEMKNQSLNLFQRRDEMDELEGFQQQELSKVKHMLLKKEESLGKMEQELEARTRELSRTQEELVTSSQISLDLSQKLEELQRHYSALEEQRDHVTASKTGAENKITVLEQKEQELQAFIQQLSIDLQKVTAETQEKEKLITHLQEKVASLEKRLEQNLSGEEHVQELLKEKTLAEQNLEDTRQQLLAARSSQAKAINNLETRVKELEQSLQASEEELKRSGDVVAAREAQIRELAAANTESSRAQQQALALEQQQAERIHALETQLAGLGRARVADLTATEQELRKLEQENAALKESKNECECSLQHHQLELKKLKEEWSQREIVSVAMAQALEEVRKQREELQQQAADLTAMMGEKEQSLQEKMEVILQKEQEILQLKKGHDSALLQTRQLQSELEALQGLRAEEATATREDLLRLTGQERPLVLSASKPHVTSRARQDPEYQLPAVEGIPNGEMGAATDLGQLQKEKQDLEQQLLEKNKTIKQMQQRMLELKKTLQKELKIRPDNELFEVREKPGPEMSNLAPSVTNNADLTDAREINFEYLKHVVLKFMSCRESEAFHLIKAVSVLLNFSQEEENMLKETLEYKMSWFGSKPAPKGSIRPSISNPRTPWS", "length": 825, "header": "tr|A0AAA9TRT2-1|A0AAA9TRT2_BOVIN Computationally mapped isoform of Golgin subfamily A member 1 OS=Bos taurus OX=9913 GN=GOLGA1 PE=4 SV=2 CANONICAL=E1BFF9-1" }, "locus": { "chromosome": "11", "start_pos": 95910799, "end_pos": 95869963, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000134579.2", "url": "https://www.ensembl.org/id/ENSBTAT00000134579.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101082.2", "url": "https://www.ensembl.org/id/ENSBTAP00000101082.2" } ] } }, { "isoform_ac": "A0AAA9TY13-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TY13/entry", "sequence": { "sequence": "MLRSDTPVPQTFGLHFSGNAASLDNWAFLGTCLGIPGCWPNNCCSGQALVISVGEPHSKMFAKLKKKIAEETAVAQRPGGATRIPRSVSKESVASMGADSGDDFASDGSSSREDLSSQLLRRNEQIRKLEARLSDYAEQVRTLQKIKEKLEIALEKHQDSSMRKFQEQNETFQANRARMAEGLALALARKDQEWSEKVDQLEKDKRFLTAQLQEMKNQSLNLFQRRDEMDELEGFQQQELSKVKHMLLKKEESLGKMEQELEARTRELSRTQEELVTSSQISLDLSQKLEELQRHYSALEEQRDHVTASKTGAENKITVLEQKEQELQAFIQQLSIDLQKVTAETQEKEKLITHLQEKVASLEKRLEQNLSGEEHVQELLKEKTLAEQNLEDTRQQLLAARSSQAKAINNLETRVKELEQSLQASEEELKRSGDVVAAREAQIRELAAANTESSRAQQQALALEQQQAERIHALETQLAGLGRARVADLTATEQELEEWSQREIVSVAMAQALEEVRKQREELQQQAADLTAMMGEKEQSLQEKMEVILQKEQEILQLKKGHDSALLQTRQLQSELEALQGLRAEEATATREDLLRLTGQERPLVLSASKPHVTSRARQDPEYQLPAVEGIPNGEMGAATDLGQLQKEKQDLEQQLLEKNKTIKQMQQRMLELKKTLQKELKIRPDNELFEVREKPGPEMSNLAPSVTNNADLTDAREINFEYLKHVVLKFMSCRESEAFHLIKAVSVLLNFSQEEENMLKETLEYKMSWFGSKPAPKGSIRPSISNPRTPWS", "length": 793, "header": "tr|A0AAA9TY13-1|A0AAA9TY13_BOVIN Computationally mapped isoform of Golgin subfamily A member 1 OS=Bos taurus OX=9913 GN=GOLGA1 PE=4 SV=1 CANONICAL=E1BFF9-1" }, "locus": { "chromosome": "11", "start_pos": 95910799, "end_pos": 95869963, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102629.1", "url": "https://www.ensembl.org/id/ENSBTAT00000102629.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103245.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103245.1" } ] } }, { "isoform_ac": "E1BFF9-1", "url": "https://www.uniprot.org/uniprotkb/E1BFF9/entry", "sequence": { "sequence": "MLRSDTPVPQTFGLHFSGNAASLDNWAFLGTCLGIPGCWPNNCCSGQALVISVGEPHSKMFAKLKKKIAEETAVAQRPGGATRIPRSVSKESVASMGADSGDDFASDGSSSREDLSSQLLRRNEQIRKLEARLSDYAEQVRTLQKIKEKLEIALEKHQDSSMRKFQEQNETFQANRARMAEGLALALARKDQEWSEKVDQLEKDKRFLTAQLQEMKNQSLNLFQRRDEMDELEGFQQQELSKVKHMLLKKEESLGKMEQELEARTRELSRTQEELVTSSQISLDLSQKLEELQRHYSALEEQRDHVTASKTGAENKITVLEQKEQELQAFIQQLSIDLQKVTAETQEKEKLITHLQEKVASLEKRLEQNLSGEEHVQELLKEKTLAEQNLEDTRQQLLAARSSQAKAINNLETRVKELEQSLQASEEELKRSGDVVAAREAQIRELAAANTESSRAQQQALALEQQQAERIHALETQLAGLGRARVADLTATEQELRKLEQENAALKESKNECECSLQHHQLELKKLKEEWSQREIVSVAMAQALEEVRKQREELQQQAADLTAMMGEKEQSLQEKMEVILQKEQEILQLKKGHDSALLQTRQLQSELEALQGLRAEEATATREDLLRLTGQERPLVLSASKPHVTSRARQDPEYQLPAVEGIPNGEMGAATDLGQLQKEKQDLEQQLLEKNKTIKQMQQRMLELKKTLQKELKIRPDNELFEVREKPGPEMSNLAPSVTNNADLTDAREINFEYLKHVVLKFMSCRESEAFHLIKAVSVLLNFSQEEENMLKETLEYKLALKAEALSLCQEGRQPIHHVVMMLDRQAFKTVPRRADPPASAVKSQLSEAGFFQLPFPVCKFGFR", "length": 865, "header": "tr|E1BFF9-1|E1BFF9_BOVIN Isoform 1 of Golgin subfamily A member 1 OS=Bos taurus OX=9913 GN=GOLGA1 PE=4 SV=2 CANONICAL=E1BFF9-1" }, "locus": { "chromosome": "11", "start_pos": 95910799, "end_pos": 95869468, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020327.7", "url": "https://www.ensembl.org/id/ENSBTAT00000020327.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020327.6", "url": "https://www.ensembl.org/id/ENSBTAP00000020327.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-6811440", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6811440", "resource": "Reactome", "description": "Retrograde transport at the Trans-Golgi-Network" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "E1BFF9", "url": "https://www.uniprot.org/uniprotkb/E1BFF9" } ], "pmid": "" }, { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "E1BFF9", "url": "https://www.uniprot.org/uniprotkb/E1BFF9" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "E1BFF9", "url": "https://www.uniprot.org/uniprotkb/E1BFF9" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "E1BFF9", "url": "https://www.uniprot.org/uniprotkb/E1BFF9" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "E1BFF9", "url": "https://www.uniprot.org/uniprotkb/E1BFF9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "transepithelial transport", "id": "GO:0070633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070633", "evidence": [ { "database": "UniProtKB", "id": "E1BFF9", "url": "https://www.uniprot.org/uniprotkb/E1BFF9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "molecular carrier activity", "id": "GO:0140104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140104", "evidence": [ { "database": "UniProtKB", "id": "E1BFF9", "url": "https://www.uniprot.org/uniprotkb/E1BFF9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 369, "end_pos": 371, "annotation": "n_glycosylation_sequon" }, { "start_pos": 692, "end_pos": 694, "annotation": "n_glycosylation_sequon" }, { "start_pos": 783, "end_pos": 785, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BFF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFF9" }, { "id": "PS50913", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50913" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GRIP", "eco_id": "ECO_0000259", "start_pos": 746, "end_pos": 795, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 169, "end_pos": 171 }, { "start_pos": 217, "end_pos": 219 }, { "start_pos": 369, "end_pos": 371 }, { "start_pos": 692, "end_pos": 694 }, { "start_pos": 783, "end_pos": 785 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BKI5-1", "uniprot_ac": "E1BKI5", "uniprot_id": "E1BKI5_BOVIN", "mass": { "chemical_mass": 21838.0, "monoisotopic_mass": 21838.0 }, "refseq": { "ac": "XP_005208869", "name": "angiopoietin-like protein 8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005208869" }, "gene_names": [ { "name": "ANGPTL8", "type": "recommended", "evidence": [ { "id": "E1BKI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKI5" } ] }, { "name": "ANGPTL8", "type": "synonym", "evidence": [ { "id": "XP_005208869", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005208869" } ] } ], "protein_names": [ { "name": "Angiopoietin like 8", "type": "synonym", "evidence": [ { "id": "E1BKI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKI5/entry#names_and_taxonomy" } ] }, { "name": "angiopoietin-like protein 8", "type": "synonym", "evidence": [ { "id": "XP_005208869", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005208869" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BKI5", "url": "https://www.uniprot.org/uniprotkb/E1BKI5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ANGPTL8", "url": "https://www.uniprot.org/uniprotkb/E1BKI5", "locus": { "chromosome": "7", "start_pos": 15662231, "end_pos": 15656028, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009570", "url": "https://www.ensembl.org/id/ENSBTAG00000009570" } ] } } ], "crossref": [ { "id": "E1BKI5", "url": "https://alphafold.ebi.ac.uk/entry/E1BKI5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000009570", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009570", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "101902412", "url": "https://www.ncbi.nlm.nih.gov/gene/101902412", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026614", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026614", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:101902412", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:101902412", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BKI5", "url": "https://www.orthodb.org/?gene=E1BKI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21463", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21463", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21463:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21463:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "R-BTA-8963889", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8963889", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005208869", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005208869", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BKI5", "url": "https://www.uniprot.org/uniprotkb/E1BKI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKI5-1", "url": "https://www.uniprot.org/uniprotkb/E1BKI5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPMLVLCLLCALAMTAQPALVGSMSGSEPAQQEELTLLFHGALQLSQALNGVYKATEAQLIKARNSLSLYGQVLGLLGKEVSQGQDAAQELRASLLEMQIEEDGLKLQAEATAQALGEVARGQQVLQEKMKQLEVQLKGVWLGHVRQEFEALKAHADEQSHIVWVLTGHVQRQKQEMMAQQQRLRQIQERLHMAALPA", "length": 198, 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The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [ "R-ALL-425425" ], "output_participant_list": [], "enzyme_list": [ "E1BHD3-1", "E1BPA4-1", "F1MPL2-1", "Q95323-1" ], "evidence": [ { "id": "R-BTA-1475017", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1475017" } ] }, { "id": "R-BTA-1475025", "name": "Carbonic anhydrase hydrates carbon dioxide (plasma membrane)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BHD3-1", "E1BPA4-1", "F1MPL2-1", "Q95323-1" ], "evidence": [ { "id": "R-BTA-1475025", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1475025" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-425425", "participant_name": "HCO3- [extracellular region]", "crossref": [ { "id": "17544", "database": "ChEBI", "url": "" }, { "id": "11533114", "database": "PubChem Substance", "url": "" }, { "id": "C00288", "database": "COMPOUND", "url": "" }, { "id": "ZINC000006827693", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "E1BHD3", "gene_name": "CA14", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "E1BHD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHD3" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "E1BHD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHD3" } ] } ] }, { "uniprot_ac": "E1BPA4", "gene_name": "CA9", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "E1BPA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA4" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "E1BPA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA4" } ] } ] }, { "uniprot_ac": "F1MPL2", "gene_name": "CA12", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "F1MPL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPL2" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "F1MPL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPL2" } ] } ] }, { "uniprot_ac": "Q95323", "gene_name": "CA4", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "Q95323", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95323" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "Q95323", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95323" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BHD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHD3" }, { "id": "PS51144", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51144" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-carbonic anhydrase", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 278, "start_aa": "Gln", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "4.2.1.1", "ec_name": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "4.2.1.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.1" }, { "id": "4.2.1.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=4.2.1.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 213, "end_pos": 215 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BIS5-1", "uniprot_ac": "E1BIS5", "uniprot_id": "E1BIS5_BOVIN", "mass": { "chemical_mass": 50007.0, "monoisotopic_mass": 50007.0 }, "refseq": { "ac": "NP_001179275", "name": "RCC1-like G exchanging factor-like protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179275" }, "gene_names": [ { "name": "RCC1L", "type": "recommended", "evidence": [ { "id": "E1BIS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIS5" } ] }, { "name": "RCC1L", "type": "synonym", "evidence": [ { "id": "NP_001179275", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179275" } ] } ], "protein_names": [ { "name": "RCC1-like G exchanging factor-like protein", "type": "recommended", "evidence": [ { "id": "E1BIS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIS5/entry#names_and_taxonomy" } ] }, { "name": "RCC1-like G exchanging factor-like protein", "type": "synonym", "evidence": [ { "id": "NP_001179275", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179275" } ] }, { "name": "Williams-Beuren syndrome chromosomal region 16 protein", "type": "synonym", "evidence": [ { "id": "NP_001179275", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179275" } ] } ], "function": [ { "annotation": "Guanine nucleotide exchange factor (GEF) for mitochondrial dynamin-related GTPase OPA1. Activates OPA1, by exchanging bound GDP for free GTP, and drives OPA1 and MFN1-dependent mitochondrial fusion. Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.", "evidence": [ { "database": "UniProtKB", "id": "E1BIS5", "url": "https://www.uniprot.org/uniprotkb/E1BIS5#function" }, { "database": "UniProtKB", "id": "ARBA00059435", "url": "https://www.uniprot.org/uniprotkb/ARBA00059435#function" }, { "database": "UniProtKB", "id": "A0AAA9SWQ5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWQ5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BIS5", "url": "https://www.uniprot.org/uniprotkb/E1BIS5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RCC1L", "url": "https://www.uniprot.org/uniprotkb/E1BIS5", "locus": { "chromosome": "25", "start_pos": 32669753, "end_pos": 32693531, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011753", "url": "https://www.ensembl.org/id/ENSBTAG00000011753" } ] } } ], "crossref": [ { "id": "E1BIS5", "url": "https://alphafold.ebi.ac.uk/entry/E1BIS5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011753", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011753", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "513273", "url": "https://www.ncbi.nlm.nih.gov/gene/513273", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000408", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000408", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009091", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009091", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058923", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058923", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:513273", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513273", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GSFCMAL", "url": "https://omabrowser.org/oma/group/GSFCMAL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BIS5", "url": "https://www.orthodb.org/?gene=E1BIS5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46337", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46337", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46337:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46337:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00415", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00415", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13540", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13540", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25390", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25390", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179275", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179275", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SWQ5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SWQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TYK3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TYK3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIS5", "url": "https://www.uniprot.org/uniprotkb/E1BIS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIS5-1", "url": "https://www.uniprot.org/uniprotkb/E1BIS5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVVTLAAVARLGRRLSGLGPGRGHWTAAGRSRSRREAAEAEADAPVFQYVGERATRADRIFVWGFSFSGALGVPTFVLPGSGPQPRAGSRPRRRIQPVPYRLELDQKISSAACGYGFTLLSSKTKDITKVWGMGLNKDSQLGFHRSRKDKTRGYEYVLEPSPVPLPLDRPQETRVLQVSCGRAHSLVLTDGEGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQVACGQDHSLFLTDQGEVYSCGWGADGQTGLGHYNITSTPTKLGGDLAGVNVVQVATYGDCCLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLPFSGVGQVKQAACGGTGCAVLNGEGHVFVWGYGILGKGPNLLETALPEMIPPTLFGLSEFNPGVQVSRIRCGLSHFAALTNRGELFVWGKNIRGCLGIGRLEDQYFPWRVTMPGEPMDVACGVDHMVTLARSFI", "length": 464, "header": "tr|E1BIS5-1|E1BIS5_BOVIN Isoform 1 of RCC1-like G exchanging factor-like protein OS=Bos taurus OX=9913 GN=RCC1L PE=4 SV=1 CANONICAL=E1BIS5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SWQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWQ5/entry", "sequence": { "sequence": "MAVVTLAAVARLGRRLSGLGPGRGHWTAAGRSRSRREAAEAEADAPVFQYVGERATRADRIFVWGFSFSGALGVPTFVLPGSGPQPRAGSRPRRRIQPVPYRLELDQKISSAACGYGFTLLSSKTKDITKVWGMGLNKDSQLGFHRSRKDKTRGYEYVLEPSPVPLPLDRPQETRVLQVSCGRAHSLVLTDGEGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQVACGQDHSLFLTDQGEVYSCGWGADGQTGLGHYNITSTPTKLGGDLAGVNVVQVATYGDCCLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLPFSGVGQVKQAACGGTGCAVLNGEGHVFVWGYGILGKGPNLLETALPEMIPPTLFGLSEFNPGVQVSRIRCGLSHFAALTSDYAWGAHGCGVWCGSYGDSGQVLHLNLLLDLLEPGPGLRTAWPAQPGQPQGSGWGPRGSGPAVRWAALPTAWSGVTGSAGGGSPSSPG", "length": 499, "header": "tr|A0AAA9SWQ5-1|A0AAA9SWQ5_BOVIN Computationally mapped isoform of RCC1-like G exchanging factor-like protein OS=Bos taurus OX=9913 GN=RCC1L PE=4 SV=1 CANONICAL=E1BIS5-1" }, "locus": { "chromosome": "25", "start_pos": 32693496, "end_pos": 32670258, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000098595.1", "url": "https://www.ensembl.org/id/ENSBTAT00000098595.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087670.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087670.1" } ] } }, { "isoform_ac": "A0AAA9TYK3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYK3/entry", "sequence": { "sequence": "MAVVTLAAVARLGRRLSGLGPGRGHWTAAGRSRSRREAAEAEADAPVFQYVGERATRADRIFVWGFSFSGALGVPTFVLPGSGPQPRAGSRPRRRIQPVPYRLELDQKISSAACGYGFTLLSSKTKDITKVWGMGLNKDSQLGFHRSRKDKTRGYEYVLEPSPVPLPLDRPQETRVLQVSCGRAHSLVLTDGEGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQVACGQDHSLFLTDQGEVYSCGWGADGQTGECPPVLALLRSGAGEAGCVWGHRLRGVKWRRTCFRLGLRNSWEGTKPLGNRSSRNDSTHSLWPVGVQPGSPGFPHSLRAQPLRRPDQPRRAVCVGQEHPRVPGNRSPGRPVLPVEGDYAWGAHGCGVWCGSYGDSGQVLHLNLLLDLLEPGPGLRTAWPAQPGQPQGSGWGPRGSGPAVRWAALPTAWSGVTGSAGGGSPSSPG", "length": 467, "header": "tr|A0AAA9TYK3-1|A0AAA9TYK3_BOVIN Computationally mapped isoform of RCC1 like OS=Bos taurus OX=9913 GN=RCC1L PE=4 SV=1 CANONICAL=E1BIS5-1" }, "locus": { "chromosome": "25", "start_pos": 32693496, "end_pos": 32670258, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104201.1", "url": "https://www.ensembl.org/id/ENSBTAT00000104201.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103702.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103702.1" } ] } }, { "isoform_ac": "E1BIS5-1", "url": "https://www.uniprot.org/uniprotkb/E1BIS5/entry", "sequence": { "sequence": "MAVVTLAAVARLGRRLSGLGPGRGHWTAAGRSRSRREAAEAEADAPVFQYVGERATRADRIFVWGFSFSGALGVPTFVLPGSGPQPRAGSRPRRRIQPVPYRLELDQKISSAACGYGFTLLSSKTKDITKVWGMGLNKDSQLGFHRSRKDKTRGYEYVLEPSPVPLPLDRPQETRVLQVSCGRAHSLVLTDGEGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQVACGQDHSLFLTDQGEVYSCGWGADGQTGLGHYNITSTPTKLGGDLAGVNVVQVATYGDCCLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLPFSGVGQVKQAACGGTGCAVLNGEGHVFVWGYGILGKGPNLLETALPEMIPPTLFGLSEFNPGVQVSRIRCGLSHFAALTNRGELFVWGKNIRGCLGIGRLEDQYFPWRVTMPGEPMDVACGVDHMVTLARSFI", "length": 464, "header": "tr|E1BIS5-1|E1BIS5_BOVIN Isoform 1 of RCC1-like G exchanging factor-like protein OS=Bos taurus OX=9913 GN=RCC1L PE=4 SV=1 CANONICAL=E1BIS5-1" }, "locus": { "chromosome": "25", "start_pos": 32693496, "end_pos": 32670449, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015608.7", "url": "https://www.ensembl.org/id/ENSBTAT00000015608.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015608.5", "url": "https://www.ensembl.org/id/ENSBTAP00000015608.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:513273", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513273", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0M5M7-1", "protein_name": "RCC1-like G exchanging factor-like protein", "gene_name": "Rcc1l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLAVARALLERRLSWPVPAREHWRPAGRSRSRREAAEAEADAPVFQYVGERAARADRVFVWGFSFSGALGVPSFVVPSSGPGPRAGLRPRRRIQPVPYRLELDHKISSAACGYGFTLLSSKTKDVTKVWGMGLNKDSQLGFHRSRKDKTRGYEYVLEPSPVPLPLDRPQETKVLQVSCGRAHSLVLTDREGVFSMGNNAHGQCGRKVVEDEVYSESHKVHRMQDFEGQVVQVVCGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSTPSKLGGDLAGVTVVQVATYGDCCLALSADGGVFGWGNSEYLQLASVTDSTQVNVPRCLPFSGVGKVKQVACGGTGCAILNEEGHVFVWGYGILGKGPNLSETALPEMIPPTLFGLTEFNPEVKVSQIRCGLSHFAALTNKGELFVWGKNIRGCLGIGRLEDQYFPWRENESMRGPGGGQSRTPAPHLPSPKPRD", "length": 463 }, "evidence": [ { "id": "E1BIS5", "url": "https://omabrowser.org/oma/group/E1BIS5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96I51-1", "protein_name": "RCC1-like G exchanging factor-like protein", "gene_name": "RCC1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALVALVAGARLGRRLSGPGLGRGHWTAAGRSRSRREAAEAEAEVPVVQYVGERAARADRVFVWGFSFSGALGVPSFVVPSSGPGPRAGARPRRRIQPVPYRLELDQKISSAACGYGFTLLSSKTADVTKVWGMGLNKDSQLGFHRSRKDKTRGYEYVLEPSPVSLPLDRPQETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDCCLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACGGTGCAVLNGEGHVFVWGYGILGKGPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGLSHFAALTNKGELFVWGKNIRGCLGIGRLEDQYFPWRVTMPGEPVDVACGVDHMVTLAKSFI", "length": 464 }, "evidence": [ { "id": "E1BIS5", "url": "https://omabrowser.org/oma/group/E1BIS5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CYF5-1", "protein_name": "RCC1-like G exchanging factor-like protein", "gene_name": "Rcc1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLAAARALRGPRPRWPTPAREHWTPAGRSRSRREAAEAEADVPVFQYVGERAARADRVFVWGFSFSGALGVPSFVVPSSGPGPRAGLRPRRRIQPVPYRLELDHKISSAACGYGFTLLSSKTKDVTKVWGMGLNKDSQLGFHRSRKDKTRGYEYVLEPSPVPLPLDRPQETKVLQVSCGRAHSLVLTDREGVFSMGNNSHGQCGRKVVEDEVYSESHKVHRMQDFDGQVVQVVCGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSTPSKLGGDLAGVTVVQVATYGDCCLALSADGGVFGWGNSEYLQLASVTDSTQVNVPRCLPFSGVGKVKQVACGGTGCAVLNAEGHVFVWGYGILGKGPKLLETAIPEMIPPTLFGLTEFNPEVQVSQIRCGLSHFAALTNKGELFVWGKNIRGCLGIGRLEDQYFPWRVTMPGEPVDVACGVDHMVTLAKSFI", "length": 461 }, "evidence": [ { "id": "E1BIS5", "url": "https://omabrowser.org/oma/group/E1BIS5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VPU0-1", "protein_name": "RCC1-like domain-containing protein", "gene_name": "Dmel\\CG3862", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLKTRGIVLGISRSYTAKAKRGVLAQDKSKIKEYSPKTTDSHEHRVYVWGFQETGALGLQTNVKKAKERYTEMVHHPTRLQFSNNNEITDVAAGYGFTVYAVNRDDGETLFGSGLNTDSQLGFQVKGNPNDPANLDVIIYPTAIKLPRVQGETDEDMRVKSMSAGRAHLVVLTQNGTIFTLGNNSYGQCGRSIIEEERYSKSALIHRISQEDICGKEDEVVQVECGQDHSMFLTKKGRIYTCGWGADGQTGQGNYHTAGQITLIGGDVEKEKIVRLSCSSDCVLALNEAGDAFGWGNSEYGQLDDSELAETQINIPRALKLTKSIGKIKDVAAGGSFCMALNDQGLVYTWGFGILGFGPFVEQTSKPQHLLPPLFGRNDFSNETTVVSIGCGVFHMGAVNSDGDLFMWGKNRFGHLGLGHKKDQFFPFKAAINGKVTKVAYGVDHTIALCKPFF", "length": 454 }, "evidence": [ { "id": "E1BIS5", "url": "https://omabrowser.org/oma/group/E1BIS5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "E1BIS5", "url": "https://www.uniprot.org/uniprotkb/E1BIS5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mitochondrial fusion", "id": "GO:0008053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008053", "evidence": [ { "database": "UniProtKB", "id": "E1BIS5", "url": "https://www.uniprot.org/uniprotkb/E1BIS5" } ], "pmid": "" }, { "name": "mitochondrial ribosome assembly", "id": "GO:0061668", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061668", "evidence": [ { "database": "UniProtKB", "id": "E1BIS5", "url": "https://www.uniprot.org/uniprotkb/E1BIS5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "E1BIS5", "url": "https://www.uniprot.org/uniprotkb/E1BIS5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BIS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIS5" }, { "id": "PF25390", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25390" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RCC1-like", "eco_id": "ECO_0000259", "start_pos": 58, "end_pos": 328, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 200, "end_pos": 202 }, { "start_pos": 268, "end_pos": 270 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BEC7-1", "uniprot_ac": "E1BEC7", "uniprot_id": "E1BEC7_BOVIN", "mass": { "chemical_mass": 19628.0, "monoisotopic_mass": 19628.0 }, "refseq": {}, "gene_names": [ { "name": "NDUFAF2", "type": "recommended", "evidence": [ { "id": "E1BEC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEC7" } ] } ], "protein_names": [ { "name": "NADH:ubiquinone oxidoreductase complex assembly factor 2", "type": "synonym", "evidence": [ { "id": "E1BEC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEC7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BEC7", "url": "https://www.uniprot.org/uniprotkb/E1BEC7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NDUFAF2", "url": "https://www.uniprot.org/uniprotkb/E1BEC7", "locus": { "chromosome": "20", "start_pos": 18209414, "end_pos": 18370943, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021607", "url": "https://www.ensembl.org/id/ENSBTAG00000021607" } ] } } ], "crossref": [ { "id": "E1BEC7", "url": "https://alphafold.ebi.ac.uk/entry/E1BEC7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021607", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021607", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "767961", "url": "https://www.ncbi.nlm.nih.gov/gene/767961", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052618", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052618", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HKTWAGQ", "url": "https://omabrowser.org/oma/group/HKTWAGQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BEC7", "url": "https://www.orthodb.org/?gene=E1BEC7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32470", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32470", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32470:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32470:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6799198", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6799198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9SXT9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SXT9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXT9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEC7", "url": "https://www.uniprot.org/uniprotkb/E1BEC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEC7-1", "url": "https://www.uniprot.org/uniprotkb/E1BEC7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGWSQRLFGVIRRALSKEVKEQVGTDRFGNKYYYIPEYKNWRGQTIREKRIVEAANKSEIDYEVGDIPTEWEAWIRKTRQTPPTMEEIMKNEKCREEIQMKSQDFYEKEKLLQEESNKELPPPVQTQIKGHASAPYFGKDEPSVSPTSTGKTFQPGSWMPHGDKGHSQ", "length": 168, "header": "tr|E1BEC7-1|E1BEC7_BOVIN Isoform 1 of NADH:ubiquinone oxidoreductase complex assembly factor 2 OS=Bos taurus OX=9913 GN=NDUFAF2 PE=3 SV=2 CANONICAL=E1BEC7-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SXT9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXT9/entry", "sequence": { "sequence": "MGWSQRLFGVIRRALSKEVKEQVGTDRFGNKYYYIPEYKNWRGQTIREKRIVEAANKSEIDYEVGDIPTEWEAWIRKTRQTPPTMEASSSWILVCQPLLSIGGFEIGIPVPWVHRDFLWDIQEIMKNEKCREEIQMKSQDFYEKEKLLQEESNKELPPPVQTQIKGHASAPYFGKDEPSVSPTSTGKTFQPGSWMPHGDKGHSQ", "length": 204, "header": "tr|A0AAA9SXT9-1|A0AAA9SXT9_BOVIN Computationally mapped isoform of NADH:ubiquinone oxidoreductase complex assembly factor 2 OS=Bos taurus OX=9913 GN=NDUFAF2 PE=3 SV=1 CANONICAL=E1BEC7-1" }, "locus": { "chromosome": "20", "start_pos": 18370904, "end_pos": 18210418, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000100054.1", "url": "https://www.ensembl.org/id/ENSBTAT00000100054.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089050.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089050.1" } ] } }, { "isoform_ac": "E1BEC7-1", "url": "https://www.uniprot.org/uniprotkb/E1BEC7/entry", "sequence": { "sequence": "MGWSQRLFGVIRRALSKEVKEQVGTDRFGNKYYYIPEYKNWRGQTIREKRIVEAANKSEIDYEVGDIPTEWEAWIRKTRQTPPTMEEIMKNEKCREEIQMKSQDFYEKEKLLQEESNKELPPPVQTQIKGHASAPYFGKDEPSVSPTSTGKTFQPGSWMPHGDKGHSQ", "length": 168, "header": "tr|E1BEC7-1|E1BEC7_BOVIN Isoform 1 of NADH:ubiquinone oxidoreductase complex assembly factor 2 OS=Bos taurus OX=9913 GN=NDUFAF2 PE=3 SV=2 CANONICAL=E1BEC7-1" }, "locus": { "chromosome": "20", "start_pos": 18370904, "end_pos": 18210418, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028793.5", "url": "https://www.ensembl.org/id/ENSBTAT00000028793.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028793.4", "url": "https://www.ensembl.org/id/ENSBTAP00000028793.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-6799198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6799198", "resource": "Reactome", "description": "Complex I biogenesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JZF6-1", "protein_name": "NADH:ubiquinone oxidoreductase complex assembly factor 2", "gene_name": "Ndufaf2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWWRGVVRSVWSALSREVREHVGTDHLGNKYYYVAEYKNWRGQTMREKRIVETANRTEVDYEAGDIPTEWEAWIRRKRKTPPTMEEILKNEKYREEIKIKSQDFYEKDKLGKETSEELLPSPTATQIKGHASAPYFGKEEPSVVPTSTGKTFQPGSWVPEDRKRQ", "length": 166 }, "evidence": [ { "id": "E1BEC7", "url": "https://omabrowser.org/oma/group/E1BEC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3GV17-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2", "gene_name": "Ndufaf2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGWWWSVLRSVWSVLSKEVREHVGTDHLGNKYYYIPKYKNWRGQTIREKRIVEAANRKELDYEAGDIPTEWEAWIRRTRKTPPTMEEILKNEKYREEIKIKSKDFYEKDKLSKETSEELLPAPAATQIKGHASAPHFGKEEPSVAPTSTGKTFQPGSWMPEDSKRQNQ", "length": 168 }, "evidence": [ { "id": "E1BEC7", "url": "https://omabrowser.org/oma/group/E1BEC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q59J78-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2", "gene_name": "Ndufaf2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSWWSGVWRSVWSALSREVREHVGTDHLGNKYYYVAEYKNWRGQTIREKRIVEAANRKEVDYEAGDIPTEWEAWIRRTRKTPPTMEEILKNEKYREEIKIKSQDFYEKDKLGKETSEELLPSPTATQVKGHASAPYFGREEPSVAPTSTGKTFQPGSWTPEDGKRQSQ", "length": 168 }, "evidence": [ { "id": "E1BEC7", "url": "https://omabrowser.org/oma/group/E1BEC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N183-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2", "gene_name": "NDUFAF2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGWSQDLFRALWRSLSREVKEHVGTDQFGNKYYYIPQYKNWRGQTIREKRIVEAANKKEVDYEAGDIPTEWEAWIRRTRKTPPTMEEILKNEKHREEIKIKSQDFYEKEKLLSKETSEELLPPPVQTQIKGHASAPYFGKEEPSVAPSSTGKTFQPGSWMPRDGKSHNQ", "length": 169 }, "evidence": [ { "id": "E1BEC7", "url": "https://omabrowser.org/oma/group/E1BEC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "R4GHM9-1", "protein_name": "NADH:ubiquinone oxidoreductase complex assembly factor 2", "gene_name": "NDUFAF2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGRAWQALRALRLRLLGPAKELVGTDQFGNKYYRVPQHQTGAGQIKPERRFVEAVNRQAYQYEMGDFPTEWEAWIRKKRKDPPTIEEILKNENYRQEMKQKVKEMYEKDKLLQTKEYKEGLVAEPIHTQVKGHASAPYYGKKEPSQDPTSTASTFQPGSWMPPGSDSSKKK", "length": 171 }, "evidence": [ { "id": "E1BEC7", "url": "https://omabrowser.org/oma/group/E1BEC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "E1BEC7", "url": "https://www.uniprot.org/uniprotkb/E1BEC7" } ], "pmid": "" }, { "name": "respiratory chain complex I", "id": "GO:0045271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045271", "evidence": [ { "database": "UniProtKB", "id": "E1BEC7", "url": "https://www.uniprot.org/uniprotkb/E1BEC7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mitochondrial respiratory chain complex I assembly", "id": "GO:0032981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032981", "evidence": [ { "database": "UniProtKB", "id": "E1BEC7", "url": "https://www.uniprot.org/uniprotkb/E1BEC7" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "E1BEC7", "url": "https://www.uniprot.org/uniprotkb/E1BEC7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "E1BEC7", "url": "https://www.uniprot.org/uniprotkb/E1BEC7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 56, "end_pos": 58 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BGI8-1", "uniprot_ac": "E1BGI8", "uniprot_id": "E1BGI8_BOVIN", "mass": { "chemical_mass": 58775.0, "monoisotopic_mass": 58775.0 }, "refseq": { "ac": "NP_001178326", "name": "DALR anticodon-binding domain-containing protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178326" }, "gene_names": [ { "name": "DALRD3", "type": "recommended", "evidence": [ { "id": "E1BGI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGI8" } ] }, { "name": "DALRD3", "type": "synonym", "evidence": [ { "id": "NP_001178326", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178326" } ] } ], "protein_names": [ { "name": "DALR anticodon binding domain containing 3", "type": "synonym", "evidence": [ { "id": "E1BGI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGI8/entry#names_and_taxonomy" } ] }, { "name": "DALR anticodon-binding domain-containing protein 3", "type": "synonym", "evidence": [ { "id": "NP_001178326", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178326" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BGI8", "url": "https://www.uniprot.org/uniprotkb/E1BGI8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DALRD3", "url": "https://www.uniprot.org/uniprotkb/E1BGI8", "locus": { "chromosome": "22", "start_pos": 50976484, "end_pos": 50972627, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018913", "url": "https://www.ensembl.org/id/ENSBTAG00000018913" } ] } } ], "crossref": [ { "id": "E1BGI8", "url": "https://alphafold.ebi.ac.uk/entry/E1BGI8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018913", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018913", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "526885", "url": "https://www.ncbi.nlm.nih.gov/gene/526885", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009080", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009080", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037380", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037380", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:526885", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:526885", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IFVMYNC", "url": "https://omabrowser.org/oma/group/IFVMYNC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BGI8", "url": "https://www.orthodb.org/?gene=E1BGI8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16043", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16043", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16043:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16043:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05746", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05746", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26758", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26758", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001178326", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178326", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TE30", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TE30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TE30-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TE30-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGI8", "url": "https://www.uniprot.org/uniprotkb/E1BGI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGI8-1", "url": "https://www.uniprot.org/uniprotkb/E1BGI8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLGVEETLGALNSALGPGGPVWFKETHARHLRARDFLAPRRALQARFGDDQVPEGVVHAIVGLQGPGVAPVLCCAPTPAGLALRLQRSVVFERVLCSVAAYAAPAAPTAPTPRIVLHCPALRGSPSALRLSQLRAVIVADHLARILQAHRVSVRRVPAVRDPHMTAFLQQLRVDWPEVSEKASTEALRNRAIAELSPAGYAGALPPGTLGRVCLKELMEERGRTAGYDPNVDSCLVTEDLLSLLAELQEAVQAGAVGSSLGLAAAPDAGADSYVVLHVVSCEEEFQQQKLDLLWWKLDHQAPLSQKHLVCGPVKVAGAPSTLTAPEYYELRHTQVCKVSSLKHGKDLEQDAAWTDIFRVLSVATVKFEMLSTAPQSQLLLALADSSISTKGSKSGTFVMYNCARLATLFEGYKCSVEQGLYPTFPPVSSLDFSLLRDEGEWLLLFNSILPFSDLLRQMAALTLTRTAPGLHVTARTETVCKFLVQLSMDFSSYYNRVHILGEPRPHLFGQMFARLQLLRAVREVLHAGLAMLGLPPLSHI", "length": 541, "header": "tr|E1BGI8-1|E1BGI8_BOVIN Isoform 1 of DALR anticodon binding domain containing 3 OS=Bos taurus OX=9913 GN=DALRD3 PE=4 SV=3 CANONICAL=E1BGI8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TE30-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TE30/entry", "sequence": { "sequence": "MRLGVEETLGALNSALGPGGPVWFKETHARHLRARDFLAPRRALQARFGDDQVPEGVVHAIVGLQGPGVAPVLCCAPTPAGLALRLQRSVVFERVLCSVAAYAAPAAPTAPTPRIVLHCPALRGSPSALRLSQLRAVIVADHLARILQAHRVSVRRVPAVRDPHMTAFLQQLRVDWPEVSEKASTEALRNRAIAELSPAGYAGALPPGTLGRVCLKELMEERGRTAGYDPNVDSCLVTEDLLSLLAELQEAVQAGAVGSSLGLAAAPDAGADSYVVLHVVSCEEEFQQQKLDLLWWKLDHQAPLSQKHLVCGPVKVAGAPSTLTAPEYYELRHTQVCKVSSLKHGKDLEQDAAWTDIFRVLSVATVKFEMLSTAPQSQLLLALADSSISTKGSKSGTFVMYNCARLATLFEGYKCSVEQGLYPTFPPVSSLDFSLLRDEGEWLLLFNSILPFSDLLRQMAALTLTRTAPGLHVTARTETVCKFLVQLSMDFSSYYNRVHILGVSAQLKGRWGRLVQGKQRMRPAASSSPPGASATLVWSDVCPSAASAGRARSAPRWAGHAGSPSAESHLRPQRP", "length": 575, "header": "tr|A0AAA9TE30-1|A0AAA9TE30_BOVIN Computationally mapped isoform of DALR anticodon binding domain containing 3 OS=Bos taurus OX=9913 GN=DALRD3 PE=4 SV=1 CANONICAL=E1BGI8-1" }, "locus": { "chromosome": "22", "start_pos": 50975480, "end_pos": 50972642, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129583.2", "url": "https://www.ensembl.org/id/ENSBTAT00000129583.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095164.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095164.1" } ] } }, { "isoform_ac": "E1BGI8-1", "url": "https://www.uniprot.org/uniprotkb/E1BGI8/entry", "sequence": { "sequence": "MRLGVEETLGALNSALGPGGPVWFKETHARHLRARDFLAPRRALQARFGDDQVPEGVVHAIVGLQGPGVAPVLCCAPTPAGLALRLQRSVVFERVLCSVAAYAAPAAPTAPTPRIVLHCPALRGSPSALRLSQLRAVIVADHLARILQAHRVSVRRVPAVRDPHMTAFLQQLRVDWPEVSEKASTEALRNRAIAELSPAGYAGALPPGTLGRVCLKELMEERGRTAGYDPNVDSCLVTEDLLSLLAELQEAVQAGAVGSSLGLAAAPDAGADSYVVLHVVSCEEEFQQQKLDLLWWKLDHQAPLSQKHLVCGPVKVAGAPSTLTAPEYYELRHTQVCKVSSLKHGKDLEQDAAWTDIFRVLSVATVKFEMLSTAPQSQLLLALADSSISTKGSKSGTFVMYNCARLATLFEGYKCSVEQGLYPTFPPVSSLDFSLLRDEGEWLLLFNSILPFSDLLRQMAALTLTRTAPGLHVTARTETVCKFLVQLSMDFSSYYNRVHILGEPRPHLFGQMFARLQLLRAVREVLHAGLAMLGLPPLSHI", "length": 541, "header": "tr|E1BGI8-1|E1BGI8_BOVIN Isoform 1 of DALR anticodon binding domain containing 3 OS=Bos taurus OX=9913 GN=DALRD3 PE=4 SV=3 CANONICAL=E1BGI8-1" }, "locus": { "chromosome": "22", "start_pos": 50975463, "end_pos": 50972642, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025168.7", "url": "https://www.ensembl.org/id/ENSBTAT00000025168.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025168.6", "url": "https://www.ensembl.org/id/ENSBTAP00000025168.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 109, "start_aa": "Thr", "end_pos": 109, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr109", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 112, "start_aa": "Thr", "end_pos": 112, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr112", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 78, "start_aa": "Thr", "end_pos": 78, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr78", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:526885", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:526885", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7H026-1", "protein_name": "DALR anticodon-binding domain-containing protein 3 isoform X1", "gene_name": "Dalrd3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MATGRLGVGETLEALNAAVGPGSPVWFKETNARHLRVRDFLAPRSALQARFRDGQVPERVFSAVTCLQGPGVAPVLRCAPTPAGLSLQLQRPAVFERVLGALASYATPAKPASPGPRLVLHCPALRCNPSALRLSQLRAVLVADHLTRTLRAHGVCVRSVPSVRDPHMATFLQKLRVDWPTASKSTSTETLRTCVLAELNSVSEEETLPPGVLGRLCLKELVQRRPVAGYDPGIDNCLVTEDMLSVLSELQEAVHHWPEGGYPGLDGDPDSGVEGCMVVHVVSCEEAFQQQKLDLLWQKLDDQAPHKQKHLVCGPVKVAGVPGTQMTAPEYYELRYAQVCKASALKHGGDLAQDPAWTKNFDVLSVATIKFEMLSTAPQNQLLLADSTISTKGTKSGTFVMYNCARLATLFEGYKQGMERGLYPAFPLVSSLDFSLLHDEGEWLLLFNSVLPFLDLLSQSVSLASTPGLHITVRTEMVCKFLVQLSMDFSSYYNRVHILGVSIQQKGVCGECGGHRIKTGRQEDKPGSFSFRNLGHTSLVRCLPAYSY", "length": 548 }, "evidence": [ { "id": "E1BGI8", "url": "https://omabrowser.org/oma/group/E1BGI8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1SKI7-1", "protein_name": "DALR anticodon binding domain containing 3", "gene_name": "DALRD3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTGVDVGEPRLWPSLGSQGPQPNPRPNQLPLPEVRPQYFRFCLFLPVAMSMGRLGVEETLAALNAALGPGGPVWYKETRARHLRARDFLAPRRALQARFEEGQVPKQVIHAIAGLQGPGVAPVLRCAPTPAGLALQLQRSAVFERVLGAVATYVAPAAHAALEPRVVLHCPALRGRPCALRLSQLRAVLVADHLARALHAHRVSVRLVPAVRDPHMLTFLQQLRVEWPAASGRARTVTEALRSRALAELTPAHDSGALPPGALGQVCLKELVDERGRRAGYDPNLDSCLVTEELLSLLAELQEAVQHWPEHSSLGLAAVSDTGADGCVVVHVVSCEEEFQQQKLDLLWWKLDDQAPLRQKHLVCGPVKVAGAPGTLTAPEYYELRHMQVCKASALKYGKDLTQDPAWTEIFRVLCVATIKFEMLSTAPQNQLLLALADNSISTKGTKSGTFVMYNCARLATLFEGYRCSVEKGLYPTFPPVSSLDFSLLHDEGEWLLLFNSILPFPDLLSHTGMLACTAPGLHITARTEMVCKFLVQLSMDFSSYYNRVHILGEPRPHLFGQMFARLQLLQAVSDVLHTGLAMLGLPPLSHI", "length": 592 }, "evidence": [ { "id": "E1BGI8", "url": "https://omabrowser.org/oma/group/E1BGI8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5D0E6-1", "protein_name": "DALR anticodon-binding domain-containing protein 3", "gene_name": "DALRD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATRRLGVGETLGALNAALGPGGPVWIKETRTRHLRSRDFLAPHRALQARFDDGQVPEHLLHALACLQGPGVAPVLRCAPTPAGLSLQLQRSAVFERVLSAVAAYATPASPASLGQRVLLHCPALRSSPCALRLSQLRTVLVADHLARALRAHGVCVRLVPAVRDPHMLTFLQQLRVDWPAASERASSHTLRSHALEELTSANDGRTLSPGILGRLCLKELVEEQGRTAGYDPNLDNCLVTEDLLSVLAELQEALWHWPEDSHPGLAGASDTGTGGCLVVHVVSCEEEFQQQKLDLLWQKLVDKAPLRQKHLICGPVKVAGAPGTLMTAPEYYEFRHTQVCKASALKHGGDLAQDPAWTEIFGVLSVATIKFEMLSTAPQSQLFLALADSSISTKGTKSGTFVMYNCARLATLFESYKCSMEQGLYPTFPPVSSLDFSLLHDEGEWLLLFNSILPFPDLLSRTAVLDCTAPGLHIAVRTEMICKFLVQLSMDFSSYYNRVHILGEPRPHLFGQMFVRLQLLRAVREVLHTGLAMLGLPPLSHI", "length": 543 }, "evidence": [ { "id": "E1BGI8", "url": "https://omabrowser.org/oma/group/E1BGI8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BGI8", "url": "https://www.uniprot.org/uniprotkb/E1BGI8" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "E1BGI8", "url": "https://www.uniprot.org/uniprotkb/E1BGI8" } ], "pmid": "" }, { "name": "arginine-tRNA ligase activity", "id": "GO:0004814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004814", "evidence": [ { "database": "UniProtKB", "id": "E1BGI8", "url": "https://www.uniprot.org/uniprotkb/E1BGI8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "arginyl-tRNA aminoacylation", "id": "GO:0006420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006420", "evidence": [ { "database": "UniProtKB", "id": "E1BGI8", "url": "https://www.uniprot.org/uniprotkb/E1BGI8" } ], "pmid": "" }, { "name": "tRNA C3-cytosine methylation", "id": "GO:0106217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106217", "evidence": [ { "database": "UniProtKB", "id": "E1BGI8", "url": "https://www.uniprot.org/uniprotkb/E1BGI8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BGI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGI8" }, { "id": "SM00836", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00836" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DALR anticodon binding", "eco_id": "ECO_0000259", "start_pos": 399, "end_pos": 541, "start_aa": "Val", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 78, 109, 112 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BHZ5-1", "uniprot_ac": "E1BHZ5", "uniprot_id": "E1BHZ5_BOVIN", "mass": { "chemical_mass": 76194.0, "monoisotopic_mass": 76194.0 }, "refseq": { "ac": "NP_001192742", "name": "TBC1 domain family member 25", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192742" }, "gene_names": [ { "name": "TBC1D25", "type": "recommended", "evidence": [ { "id": "E1BHZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHZ5" } ] }, { "name": "TBC1D25", "type": "synonym", "evidence": [ { "id": "NP_001192742", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192742" } ] } ], "protein_names": [ { "name": "TBC1 domain family member 25", "type": "recommended", "evidence": [ { "id": "E1BHZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHZ5/entry#names_and_taxonomy" } ] }, { "name": "TBC1 domain family member 25", "type": "synonym", "evidence": [ { "id": "NP_001192742", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192742" } ] } ], "function": [ { "annotation": "Acts as a GTPase-activating protein specific for RAB33B. Involved in the regulation of autophagosome maturation, the process in which autophagosomes fuse with endosomes and lysosomes.", "evidence": [ { "database": "UniProtKB", "id": "E1BHZ5", "url": "https://www.uniprot.org/uniprotkb/E1BHZ5#function" }, { "database": "UniProtKB", "id": "ARBA00060246", "url": "https://www.uniprot.org/uniprotkb/ARBA00060246#function" }, { "database": "UniProtKB", "id": "A0AAA9TGJ1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGJ1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BHZ5", "url": "https://www.uniprot.org/uniprotkb/E1BHZ5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TBC1D25", "url": "https://www.uniprot.org/uniprotkb/E1BHZ5", "locus": { "chromosome": "X", "start_pos": 86678020, "end_pos": 86663704, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009288", "url": "https://www.ensembl.org/id/ENSBTAG00000009288" } ] } } ], "crossref": [ { "id": "E1BHZ5", "url": "https://alphafold.ebi.ac.uk/entry/E1BHZ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000009288", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009288", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "515568", "url": "https://www.ncbi.nlm.nih.gov/gene/515568", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:515568", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515568", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PFERQTS", "url": "https://omabrowser.org/oma/group/PFERQTS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BHZ5", "url": "https://www.orthodb.org/?gene=E1BHZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22957", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22957", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22957:SF333", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22957:SF333", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8854214", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8854214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192742", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192742", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TGJ1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TGJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHZ5", "url": "https://www.uniprot.org/uniprotkb/E1BHZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHZ5-1", "url": "https://www.uniprot.org/uniprotkb/E1BHZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATASGSSDLAGSGAPSPGGGAQAAAAEEEEREVVRVRVKKCESFLPLEFRSFAVDPQITSLDVLQHILIRAFDLNGKKNFGISYLGRDRMGQEAYLSLLSDWDLSTAFATASKPYLHLRVDIRPTEDSPLLEDWDIISPKDVIGSDVLLAEKRSSLTTAALPFTQSIISQVGRTLSKVQQVLSWSYGEDVKPFKPPLSDAEFHTYLNHEGQLSRPEELRLRIYHGGVEPSLRKVVWRYLLNVYPDGLTGRERMDYMKRKSREYEQLKSEWAQRASPEDLEFIRSTVLKDVLRTDRAHPYYAGPEDGPHLRALHDLLTTYAVTHPQVSYCQGMSDLASPILAVMDHEGHAFVCFCGIMKRLAANFHPDGRAMATKFAHLKLLLRHADPDFYQYLQEAGADDLFFCYRWLLLELKREFAFDDALRMLEVTWSSLPPDPPEHEVELVGPPSLVVDMGFGSHRGRPMRQRHMLRPAGGGGGAFEDAVDHLTTSSQGPGGGGRLLRQASLDDLQQLRDRTGPRRDSLIQLPYPAALIGSKSLSEPLLNSSDPLLSPSSHPDSPSSSSPPSTQDASPAGDVAAGSPLMPEVGSPQDSGKSLPPPPPLGLPPPQEFGRGNPFMLFLCLAILLEHRDHIMRNGLDYNELAMHFDRLVRKHHLGRVLRRAKALFADYLQSEMWDSEEGAEATAPS", "length": 687, "header": "tr|E1BHZ5-1|E1BHZ5_BOVIN Isoform 1 of TBC1 domain family member 25 OS=Bos taurus OX=9913 GN=TBC1D25 PE=4 SV=3 CANONICAL=E1BHZ5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TGJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGJ1/entry", "sequence": { "sequence": "MFCSFHSMIILMKSDFQTPCFHQKIWQCHKKCVRKGDFSKKKCESFLPLEFRSFAVDPQITSLDVLQHILIRAFDLNGKKNFGISYLGRDRMGQEAYLSLLSDWDLSTAFATASKPYLHLRVDIRPTEDSPLLEDWDIISPKDVIGSDVLLAEKRSSLTTAALPFTQSIISQVGRTLSKVQQVLSWSYGEDVKPFKPPLSDAEFHTYLNHEGQLSRPEELRLRIYHGGVEPSLRKVVWRYLLNVYPDGLTGRERMDYMKRKSREYEQLKSEWAQRASPEDLEFIRSTVLKDVLRTDRAHPYYAGPEDGPHLRALHDLLTTYAVTHPQVSYCQGMSDLASPILAVMDHEGHAFVCFCGIMKRLAANFHPDGRAMATKFAHLKLLLRHADPDFYQYLQEAGADDLFFCYRWLLLELKREFAFDDALRMLEVTWSSLPPDPPEHEVELVGPPSLVVDMGFGSHRGRPMRQRHMLRPAGGGGGAFEDAVDHLTTSSQGPGGGGRLLRQASLDDLQQLRDRTGPRRDSLIQLPYPAALIGSKSLSEPLLNSSDPLLSPSSHPDSPSSSSPPSTQDASPAGDVAAGSPLMPEVGSPQDSGKSLPPPPPLGLPPPQEFGRGNPFMLFLCLAILLEHRDHIMRNGLDYNELAMHFDRLVRKHHLGRVLRRAKALFADYLQSEMWDSEEGAEATAPS", "length": 688, "header": "tr|A0AAA9TGJ1-1|A0AAA9TGJ1_BOVIN Computationally mapped isoform of TBC1 domain family member 25 OS=Bos taurus OX=9913 GN=TBC1D25 PE=4 SV=1 CANONICAL=E1BHZ5-1" }, "locus": { "chromosome": "X", "start_pos": 86677781, "end_pos": 86663753, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120289.1", "url": "https://www.ensembl.org/id/ENSBTAT00000120289.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097671.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097671.1" } ] } }, { "isoform_ac": "E1BHZ5-1", "url": "https://www.uniprot.org/uniprotkb/E1BHZ5/entry", "sequence": { "sequence": "MATASGSSDLAGSGAPSPGGGAQAAAAEEEEREVVRVRVKKCESFLPLEFRSFAVDPQITSLDVLQHILIRAFDLNGKKNFGISYLGRDRMGQEAYLSLLSDWDLSTAFATASKPYLHLRVDIRPTEDSPLLEDWDIISPKDVIGSDVLLAEKRSSLTTAALPFTQSIISQVGRTLSKVQQVLSWSYGEDVKPFKPPLSDAEFHTYLNHEGQLSRPEELRLRIYHGGVEPSLRKVVWRYLLNVYPDGLTGRERMDYMKRKSREYEQLKSEWAQRASPEDLEFIRSTVLKDVLRTDRAHPYYAGPEDGPHLRALHDLLTTYAVTHPQVSYCQGMSDLASPILAVMDHEGHAFVCFCGIMKRLAANFHPDGRAMATKFAHLKLLLRHADPDFYQYLQEAGADDLFFCYRWLLLELKREFAFDDALRMLEVTWSSLPPDPPEHEVELVGPPSLVVDMGFGSHRGRPMRQRHMLRPAGGGGGAFEDAVDHLTTSSQGPGGGGRLLRQASLDDLQQLRDRTGPRRDSLIQLPYPAALIGSKSLSEPLLNSSDPLLSPSSHPDSPSSSSPPSTQDASPAGDVAAGSPLMPEVGSPQDSGKSLPPPPPLGLPPPQEFGRGNPFMLFLCLAILLEHRDHIMRNGLDYNELAMHFDRLVRKHHLGRVLRRAKALFADYLQSEMWDSEEGAEATAPS", "length": 687, "header": "tr|E1BHZ5-1|E1BHZ5_BOVIN Isoform 1 of TBC1 domain family member 25 OS=Bos taurus OX=9913 GN=TBC1D25 PE=4 SV=3 CANONICAL=E1BHZ5-1" }, "locus": { "chromosome": "X", "start_pos": 86677781, "end_pos": 86664796, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012236.6", "url": "https://www.ensembl.org/id/ENSBTAT00000012236.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012236.6", "url": "https://www.ensembl.org/id/ENSBTAP00000012236.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:515568", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515568", "resource": "KEGG Pathway" }, { "id": "R-BTA-8854214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8854214", "resource": "Reactome", "description": "TBC/RABGAPs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A4T1-1", "protein_name": "TBC1 domain family member 25", "gene_name": "TBC1D25", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATATGSPDLAGSGAPPPGGGAQAAAAEEEEREVVRVRVKKCESFLPPEFRSFAVDPQITSLDVLQHILIRAFDLNGKKNFGISYLGRDRLGQEAYLSLLSDWDLSMAFATASKPYLHLRVDIRPTEDSPLLEDWDIISPKDVIGSDVLLAEKRSSLTTAALPFTQSILSQVGRTLSKVQQVLSWSYGEDVKPFKPPLSDAEFHTYLNHEGQLSRPEELRLRIYHGGVEPSLRKVVWRYLLNVYPDGLTGRERMDYMKRKSREYEQLKSEWAQRASPEDLEFIRSTVLKDVLRTDRAHPYYAGPEDGPHLRALHDLLTTYAVTHPQVSYCQGMSDLASPILAVMDHEGHAFVCFCGIMKRLAANFHPDGRAMATKFAHLKLLLRHADPDFYQYLQEAGADDLFFCYRWLLLELKREFAFDDALRMLEVTWSSLPPDPPEHEVELVGPPSLGADTGFGAHRGRPVRQRHMLRPAGGGGGSAFEDAVDHLAATSQGPGGSSGGRLLRQASLDDLQQLRDNTGPRRDALVQLPHPAALISSKSLSEPLLNSSDPLLSPSSRPDSPSSSSPPSTQDASPAGDAAVGSPLMPEAGSPQDPGKPLPPPPPLGLPPPQEFGRGNPFMLFLCLAILLEHRDHIMRNGLDYNELAMHFDRLVRKHHLGRVLRRAKALFADYLQSEVWDSEEGAEATAPS", "length": 690 }, "evidence": [ { "id": "E1BHZ5", "url": "https://omabrowser.org/oma/group/E1BHZ5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6ALA8-1", "protein_name": "TBC1 domain family member 25", "gene_name": "Tbc1d25", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATTSAASDLACSAAPSPVGGASAAAAVEEEEREVVRVRVKKCESFLSPEFRSFAVDPQITSLDVLQHILIRAFDLNGKKNFGISYLARDRLGQEAFLSLLSDWDLSTAFATASKPYLQLRVDIRPSEDSPLLEDWDIISPKDVIGSDVLLADKRSSLTTAALPFTQSILSQVGRTLSKVQQVLSWSYGEDVKPFKPPLSDAEFHTYLNHEGQLSRPEELRLRIYHGGVEPSLRKVVWRYLLNVYPDGLTGRERMDYMKRKSREYEQLKSEWAQRVNPEDLEFIRSTVLKDVLRTDRAHPYYAGPEDGPHLRALHDLLTTYAVTHPQVSYCQGMSDLASPILAVMDHEGHAFVCFCGIMKRLAANFHPDGRAMATKFAHLKLLLRHADPDFYQYLQEAGADDLFFCYRWLLLELKREFAFDDALRMLEVTWSSLPPDPPEHEVELVGPPSQVADTGFGSHRGRPVRQRHMLRPAGGGSSAFEDAVVHLATSSQGPSSGGRLLRQASLDGLQQLRDNMSPRKDLLVQLSHPATLISSKSLSEPLLNSPDPLLSSSSRPDSPSSSSPPSTQEASPSGDVAVGSPSMPEVGSPRDPGKSVPPPPPMGLPPPQEFGRGNPFMLFLCLAILLEHRDHIMRNGLDYNELAMHFDRLVRKHHLGRVLRRAKALFADYLQSEVWDSEEGAEATAPS", "length": 688 }, "evidence": [ { "id": "E1BHZ5", "url": "https://omabrowser.org/oma/group/E1BHZ5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1A5B6-1", "protein_name": "TBC1 domain family member 25", "gene_name": "Tbc1d25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRPPAQARWEGQGPTAPLRLRSGARWGRGRPHCWVYVRVRVTIGYHLDRDDSGGMATTSAASDSACSAAPPPVGGAQAAAAVEEEEREVVRVRVKKCESFLSPEFRSFAVDPQITSLDVLQHILIRAFDLNGKKNFGISYLARDRLGQETFLSLLSDWDLSTAFATASKPYLQLRVDIRPSEDSPLLEDWDIISPKDVIGSDVLLAEKRSSLTTAALPFTQSILSQVGRTLSKVQQVLSWSYGEDVKPFKPPLSDAEFHTYLNHEGQLSRPEELRLRIYHGGVEPSLRKVVWRYLLNVYPDGLTGRERMDYMKRKSREYEQLKSEWAQRVNPEDLEFIRSTVLKDVLRTDRAHPYYAGPEDGPHLRALHDLLTTYAVTHPQVSYCQGMSDLASPILAVMDHEGHAFVCFCGIMKRLAANFHPDGRAMATKFAHLKLLLRHADPDFYQYLQEAGADDLFFCYRWLLLELKREFAFDDALRMLEVTWSSLPPDPPEHEVELVGPPSQVADTGFGSHRGRPVRQRHMLRPAGGGGGAFEDAVVHLAASSQGPSGGGRLLRQASLDGLQQLRDNMGLRKDHLVQLSHPATLISSKSLSEPLLNSPDPLLSTSSRPDSPSSSSPPSTQEASPSGDIAVGSPLMQEVGSPRDPGKPVPPPPPMGLPPPQEFGRGNPFMLFLCLAILLEHRDHIMRNGLDYNELAMHFDRLVRKHHLGRVLRRAKALFADYLQSEVWDSEEGAEATAPS", "length": 742 }, "evidence": [ { "id": "E1BHZ5", "url": "https://omabrowser.org/oma/group/E1BHZ5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B0S696-1", "protein_name": "TBC1 domain family member 25", "gene_name": "tbc1d25", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVEEERGVVRVKVKKCEGVLPVEFRSFAVDPQITSLEVLQHILIRAFELNGKRNFGISYLSRDRAGVEVYVSLLSDWDLDAAFVSAAKPYLQLKMDIKPSEDSPVLEDWDIISPKDVIGSDQLQGEKRSLASAALPFTQSLLSQVGRTLSRVQQALSWSYGEEVKPFKPPLSDAEFHNYLNSQGQLSRPEELRLRIYHGGVESSLRKVVWRYLLNVYPDGLTGQERMDYMKRKTREYDQLKSEWTARVSSEELEFIRGNVLKDVLRTDRAHPYYAGSEDSPHLTALTDLLTTFAITHPQVSYCQGMSDIASPILAVMDNEAHAFICFCGIMKRLEGNFRPDGQLMSIKFQHLKLLLQYSDPEFYSYLVSKGADDLFFCYRWLLLELKREFAFDDALRMLEVTWSSLPPDPPETEVELLGPAFEADQSDGSHNVDMEEMEEKQTERQRRRHMLRPSREEADGERNLVMEEERGPRKEGEGEYDVESMVRNDIPAQPPSFEKQGSFGEFKYYNGRTEDSFEVNENDSSDPTLSPVQFQSAHSTLPFSVRQSTEESEDDPGEQEPLINNLTPSSPGQRDSPNGQAASPLSTLPSGLPNWKSSSNQSSNSASSWRTASPDALSKCTSSSSSGEKALSPDKPSGGFASSQPVLNGTGAQSPSVVPGKSLLASPSQGYNHSLLSSPVLSFGKSPSLPKAFSSNLPSPCRPTGSGVSSPNTNKPEGGGIKPCSLPPPQEFGKGNPFMLFLCLSILLEHRDHIIKNSLDYNELAMHFDRLVRRHNLGRILQRAKALFADYLQSEVWDSEEGDEVSLDSPTTAATSPQTPSTRPPFLNVQPSQGAFPNSTYNLANTIPSPTTPIALSPSAS", "length": 863 }, "evidence": [ { "id": "E1BHZ5", "url": "https://omabrowser.org/oma/group/E1BHZ5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3MII6-1", "protein_name": "TBC1 domain family member 25", "gene_name": "TBC1D25", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATASGASDLSGSGAPPPGVGAQAAAAAEEEEREVVRVRVKKCESFLPPEFRSFAVDPQITSLDVLQHILIRAFDLSGKKNFGISYLGRDRLGQEVYLSLLSDWDLSTAFATASKPYLQLRVDIRPSEDSPLLEDWDIISPKDVIGSDVLLAEKRSSLTTAALPFTQSILTQVGRTLSKVQQVLSWSYGEDVKPFKPPLSDAEFHTYLNHEGQLSRPEELRLRIYHGGVEPSLRKVVWRYLLNVYPDGLTGRERMDYMKRKSREYEQLKSEWAQRANPEDLEFIRSTVLKDVLRTDRAHPYYAGPEDGPHLRALHDLLTTYAVTHPQVSYCQGMSDLASPILAVMDHEGHAFVCFCGIMKRLAANFHPDGRAMATKFAHLKLLLRHADPDFYQYLQEAGADDLFFCYRWLLLELKREFAFDDALRMLEVTWSSLPPDPPEHEVELVGPPSQVADAGFGGHRGWPVRQRHMLRPAGGGGSTFEDAVDHLATASQGPGGGGRLLRQASLDGLQQLRDNMGSRRDPLVQLPHPAALISSKSLSEPLLNSPDPLLSSFSHPDSPSSSSPPSTQEASPTGDMAVGSPLMQEVGSPKDPGKSLPPVPPMGLPPPQEFGRGNPFMLFLCLAILLEHRDHIMRNGLDYNELAMHFDRLVRKHHLGRVLRRARALFADYLQSEVWDSEEGAEATAAS", "length": 688 }, "evidence": [ { "id": "E1BHZ5", "url": "https://omabrowser.org/oma/group/E1BHZ5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "E1BHZ5", "url": "https://www.uniprot.org/uniprotkb/E1BHZ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "E1BHZ5", "url": "https://www.uniprot.org/uniprotkb/E1BHZ5" } ], "pmid": "" }, { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "E1BHZ5", "url": "https://www.uniprot.org/uniprotkb/E1BHZ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "E1BHZ5", "url": "https://www.uniprot.org/uniprotkb/E1BHZ5" } ], "pmid": "" }, { "name": "regulation of autophagosome maturation", "id": "GO:1901096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901096", "evidence": [ { "database": "UniProtKB", "id": "E1BHZ5", "url": "https://www.uniprot.org/uniprotkb/E1BHZ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 544, "end_pos": 546, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BHZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHZ5" }, { "id": "PS50086", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50086" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rab-GAP TBC", "eco_id": "ECO_0000259", "start_pos": 227, "end_pos": 433, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 544, "end_pos": 546 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BFP1-1", "uniprot_ac": "E1BFP1", "uniprot_id": "E1BFP1_BOVIN", "mass": { "chemical_mass": 23029.0, "monoisotopic_mass": 23029.0 }, "refseq": { "ac": "NP_001179142", "name": "heme-binding protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179142" }, "gene_names": [ { "name": "HEBP2", "type": "recommended", "evidence": [ { "id": "E1BFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFP1" } ] }, { "name": "HEBP2", "type": "synonym", "evidence": [ { "id": "NP_001179142", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179142" } ] } ], "protein_names": [ { "name": "Heme-binding protein 2", "type": "recommended", "evidence": [ { "id": "E1BFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFP1/entry#names_and_taxonomy" } ] }, { "name": "Protein SOUL", "type": "synonym", "evidence": [ { "id": "E1BFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFP1/entry#names_and_taxonomy" } ] }, { "name": "heme-binding protein 2", "type": "synonym", "evidence": [ { "id": "NP_001179142", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179142" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BFP1", "url": "https://www.uniprot.org/uniprotkb/E1BFP1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HEBP2", "url": "https://www.uniprot.org/uniprotkb/E1BFP1", "locus": { "chromosome": "9", "start_pos": 76196894, "end_pos": 76189902, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000243", "url": "https://www.ensembl.org/id/ENSBTAG00000000243" } ] } } ], "crossref": [ { "id": "E1BFP1", "url": "https://alphafold.ebi.ac.uk/entry/E1BFP1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000243", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000243", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "509223", "url": "https://www.ncbi.nlm.nih.gov/gene/509223", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006917", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006917", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011256", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011256", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:509223", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509223", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YEIRTYH", "url": "https://omabrowser.org/oma/group/YEIRTYH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BFP1", "url": "https://www.orthodb.org/?gene=E1BFP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11220", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11220", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11220:SF70", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11220:SF70", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04832", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04832", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179142", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179142", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TLP0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TLP0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLP0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFP1", "url": "https://www.uniprot.org/uniprotkb/E1BFP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFP1-1", "url": "https://www.uniprot.org/uniprotkb/E1BFP1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEVLEPDSRAAEGSEAPVVETPGWEVPEDAGPQPGSYEVRHYGPAKWVSTAVESMDWDSAMQTGFTRLKSYLQGKNEKEMKIKMTAPVTSYVEPGSGPFSESTITISLYIPSEQQSDPPRPAESDVFIEDRAEMTVFVRSFDGFSSAQKNQEQLLTLASILREEGKVFDEKVYYTAGYNSPFKLLDRNNEVWLIQKNEPSKERE", "length": 205, "header": "tr|E1BFP1-1|E1BFP1_BOVIN Isoform 1 of Heme-binding protein 2 OS=Bos taurus OX=9913 GN=HEBP2 PE=1 SV=1 CANONICAL=E1BFP1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TLP0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLP0/entry", "sequence": { "sequence": "DGGDSQGKPDHAHGTRRRSGRPELPGSGSGSLRPLPVGAPQCSADSGLPRCAEVTRRLRGGDSGTRRRGGPERPGAAPFLAQLAGLFPGSVGAAHGRGAGARFPGSRRLGGPRGRDAGLGGPGGCWPPEMKIKMTAPVTSYVEPGSGPFSESTITISLYIPSEQQSDPPRPAESDVFIEDRAEMTVFVRSFDGFSSAQKNQEQLLTLASILREEGKVFDEKVYYTAGYNSPFKLLDRNNEVWLIQKNEPSKERE", "length": 254, "header": "tr|A0AAA9TLP0-1|A0AAA9TLP0_BOVIN Computationally mapped isoform of Heme-binding protein 2 OS=Bos taurus OX=9913 GN=HEBP2 PE=3 SV=1 CANONICAL=E1BFP1-1" }, "locus": { "chromosome": "9", "start_pos": 76196168, "end_pos": 76189904, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094761.1", "url": "https://www.ensembl.org/id/ENSBTAT00000094761.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099368.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099368.1" } ] } }, { "isoform_ac": "E1BFP1-1", "url": "https://www.uniprot.org/uniprotkb/E1BFP1/entry", "sequence": { "sequence": "MAEVLEPDSRAAEGSEAPVVETPGWEVPEDAGPQPGSYEVRHYGPAKWVSTAVESMDWDSAMQTGFTRLKSYLQGKNEKEMKIKMTAPVTSYVEPGSGPFSESTITISLYIPSEQQSDPPRPAESDVFIEDRAEMTVFVRSFDGFSSAQKNQEQLLTLASILREEGKVFDEKVYYTAGYNSPFKLLDRNNEVWLIQKNEPSKERE", "length": 205, "header": "tr|E1BFP1-1|E1BFP1_BOVIN Isoform 1 of Heme-binding protein 2 OS=Bos taurus OX=9913 GN=HEBP2 PE=1 SV=1 CANONICAL=E1BFP1-1" }, "locus": { "chromosome": "9", "start_pos": 76196168, "end_pos": 76190187, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000304.4", "url": "https://www.ensembl.org/id/ENSBTAT00000000304.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000304.3", "url": "https://www.ensembl.org/id/ENSBTAP00000000304.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:509223", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509223", "resource": "KEGG Pathway" }, { "id": "R-BTA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZHC4-1", "protein_name": "Heme-binding protein 2", "gene_name": "Hebp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEEPDLGVAEGSEEQAMEMPSWKAPENIDPQPGSYEIRHYGPAKWVSTCVESLDWDSAIQTGFTKLNGYIQGKNEKEMKIKLTAPVMSFVEPGSGPFSESTITISLYIPSEQQHDPPRPSESDVFIEDRGEMTVFVRSFDGFSSGQKNQEQLLTLANILREEGKVFNEKVFYTAGYSSPFRLLDRNNEVWLIQRNEPSDEDK", "length": 203 }, "evidence": [ { "id": "E1BFP1", "url": "https://omabrowser.org/oma/group/E1BFP1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9SHG8-1", "protein_name": "SOUL heme-binding family protein", "gene_name": "HBP1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATGLGFFKLSFLLSLLSGGSDLLGPDAESGVAQIGKFPPSCNRIECPSYELVHSGNGYEIRRYNNTVWVSTEPIPDISLVDATRTAFFQLFAYIQGKNEYHQKIEMTAPVISQVSPSDGPFCESSFTVSFYVPKKNQPDPAPSENLHIQKWNSRYVAVRQFSGFVSDDSIGEQAAALDSSLKGTAWANAIAKSKEDGGVGSDSAYTVAQYNSPFEFSGRVNEIWLPFELDV", "length": 232 }, "evidence": [ { "id": "E1BFP1", "url": "https://omabrowser.org/oma/group/E1BFP1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9WU63-1", "protein_name": "Heme-binding protein 2", "gene_name": "Hebp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEEPEPDLGVAEGSEDQALEMPSWKAPEDIDPQPGSYEIRHYGPAKWVSTCVESLDWDSAIQTGFTKLNGYIQGKNEKEMKIKLTAPVTSYVEPGSSPFSESTITISLYIPSEQQPDPPRPSESDVFIEDRAEMTVFVRSFDGFSSGQKNQEQLLTLANILREEGKVFNEKVFYTAGYSSPFQLLDRNNEVWLIQKNEPSVENK", "length": 205 }, "evidence": [ { "id": "E1BFP1", "url": "https://omabrowser.org/oma/group/E1BFP1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y5Z4-1", "protein_name": "Heme-binding protein 2", "gene_name": "HEBP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEPLQPDPGAAEDAAAQAVETPGWKAPEDAGPQPGSYEIRHYGPAKWVSTSVESMDWDSAIQTGFTKLNSYIQGKNEKEMKIKMTAPVTSYVEPGSGPFSESTITISLYIPSEQQFDPPRPLESDVFIEDRAEMTVFVRSFDGFSSAQKNQEQLLTLASILREDGKVFDEKVYYTAGYNSPVKLLNRNNEVWLIQKNEPTKENE", "length": 205 }, "evidence": [ { "id": "E1BFP1", "url": "https://omabrowser.org/oma/group/E1BFP1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "E1BFP1", "url": "https://www.uniprot.org/uniprotkb/E1BFP1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BFP1", "url": "https://www.uniprot.org/uniprotkb/E1BFP1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "E1BFP1", "url": "https://www.uniprot.org/uniprotkb/E1BFP1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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"table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "V6F977-1", "uniprot_ac": "V6F977", "uniprot_id": "V6F977_BOVIN", "mass": { "chemical_mass": 144038.0, "monoisotopic_mass": 144038.0 }, "refseq": { "ac": "XP_010810695", "name": "serine/threonine-protein kinase SIK3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010810695" }, "gene_names": [ { "name": "SIK3", "type": "recommended", "evidence": [ { "id": "V6F977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V6F977" } ] }, { "name": "SIK3", "type": "synonym", "evidence": [ { "id": "XP_010810695", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010810695" } ] } ], "protein_names": [ { "name": "Serine/threonine-protein kinase SIK3", "type": "recommended", "evidence": [ { "id": "V6F977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V6F977/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "V6F977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V6F977/entry#names_and_taxonomy" } ] }, { "name": "Salt-inducible kinase 3", "type": "synonym", "evidence": [ { "id": "V6F977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V6F977/entry#names_and_taxonomy" } ] }, { "name": "Serine/threonine-protein kinase QSK", "type": "synonym", "evidence": [ { "id": "V6F977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V6F977/entry#names_and_taxonomy" } ] }, { "name": "serine/threonine-protein kinase SIK3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_010810695", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010810695" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "V6F977", "url": "https://www.uniprot.org/uniprotkb/V6F977" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SIK3", "url": "https://www.uniprot.org/uniprotkb/V6F977", "locus": { "chromosome": "15", "start_pos": 27514715, "end_pos": 27778247, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015119", "url": "https://www.ensembl.org/id/ENSBTAG00000015119" } ] } } ], "crossref": [ { "id": "ENSBTAG00000015119", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015119", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14071", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14071", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14410", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14410", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "506539", "url": "https://www.ncbi.nlm.nih.gov/gene/506539", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034672", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034672", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057380", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057380", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:506539", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:506539", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HRYIYKD", "url": "https://omabrowser.org/oma/group/HRYIYKD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1MXE2", "url": "https://www.orthodb.org/?gene=F1MXE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "V6F977", "url": "https://www.orthodb.org/?gene=V6F977", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24346", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24346", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24346:SF42", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24346:SF42", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23312", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23312", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010810695", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010810695", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0P221", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P221", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P221-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P221-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MXE2", "url": "https://www.uniprot.org/uniprotkb/F1MXE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MXE2-1", "url": "https://www.uniprot.org/uniprotkb/F1MXE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "V6F977", "url": "https://www.uniprot.org/uniprotkb/V6F977", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "V6F977-1", "url": "https://www.uniprot.org/uniprotkb/V6F977-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAAASGAGGAAGAGAGGAGPAGRLLPPPAPGPPAAPAAVPPAAGPPRPPAPASRGPVPARIGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLKKIFREVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVAAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICKHKWMKLGDADPNFDRLIAECQQLKEERQMDPLNEDVLLAMENMGLDKERTLQSLRSDAYDHYSAIYSLLCDRHKRHKTLRVGVPPGMPRTMGFQPPVNLQAEQAGTTMNISVPQVQLINPENQIVEPDGAVNVDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKLLPGFPGVNPQAPFLQVAPNVNFMHNLLPMQNLQPTGQLEYKEQSLLQPPTLQLLNGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEAVQSSTYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLEKMGNNSSIKQLQQECEQLQKMYGGQIDERTLEKTQQQHMLYQQEQHHQILQQQIQDSICPPQPSPPLQAACENQPALLTHQLQRLRIQPSSPPPNHPNNHLFRQPSNSPPPMSSAMMQSHGATSSSQFQGFPSRSAIFQQQPENCSPPPSVALTCLGIQQPPQSQQVTIQVQEPVDMLSSMPGAAAASAGRGVSISPNTSQVQMQLRTSLMAALSYGHRPLSKQLSADSAEAHSLNVNRFSPANYDQAHLHPHLFSDQSRGSPSSYNPSSGAGLPPTQALKVPPLDQFPTFPPSAHQQPPHYTTSALQQALLSPTPPDYTRHQQVPHILQGLLSPRHSLTGHSDMRLPPAEFAQLIKRRQRQQQQQEYQELFRHMNQGDAGSLAPGLGGQSMTERQALPYQNADSYHHHHTSPQHLLQIRAQECISQVSSPTPTHSYAPQAALVHSESMEEECSCEGAKDGFPDRKSGNTLTKGCHDSPLLLSTGGPGDPESLLGTVNHAQELGIHPYRQPAAAFTRNKVSSRESVLGKCMDRSSPGQAMELPDHNGLGYPAHPSVSEHQRPRTLQRHHTIQNSDDAYVQLDNLPGMSLVAGKALSSARMSDAVLSQSSLMGSQQFQDGENEECGESLGGQEHPDLTDGSQHLNSSCYPSTCITDILLSYKHPEVSFSMEQAGV", "length": 1314, "header": "tr|V6F977-1|V6F977_BOVIN Isoform 1 of Serine/threonine-protein kinase SIK3 OS=Bos taurus OX=9913 GN=SIK3 PE=3 SV=1 CANONICAL=V6F977-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P221-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P221/entry", "sequence": { "sequence": "MKMLCHPHIIRLYQSLSHVRLFATPWTVACQTALSMGILQARILKWVAMPSFRGFSTQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVAAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICKHKWMKLGDADPNFDRLIAECQQLKEERQMDPLNEDVLLAMENMGLDKERTLQSLRSDAYDHYSAIYSLLCDRHKRHKTLRVGVPPGMPRTMGFQPPVNLQAEQAGTTMNISVPQVQLINPENQIVEPDGAVNVDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKLLPGFPGVNPQAPFLQVAPNVNFMHNLLPMQNLQPTGQLEYKEQSLLQPPTLQLLNGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEAVQRYLANRSKRHTLAMTNPTAEIPPDLQRQLGQQPFRSRVWPPHLVPDQHRSTYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLEKMGNNSSIKQLQQECEQLQKMYGGQIDERTLEKTQQQHMLYQQEQHHQILQQQIQDSICPPQPSPPLQAACENQPALLTHQLQRLRIQPSSPPPNHPNNHLFRQPSNSPPPMSSAMMQSHGATSSSQFQGFPSRSAIFQQQPENCSPPPSVALTCLGIQQPPQSQQVTIQVQEPVDMLSSMPGAAAASAGRGVSISPNTSQVQMQLRTSLMAALSYGHRPLSKQLSADSAEAHSLNVNRFSPANYDQAHLHPHLFSDQSRGSPSSYNPSSGAGLPPTQALKVPPLDQFPTFPPSAHQQPPHYTTSALQQALLSPTPPDYTRHQQVPHILQGLLSPRHSLTGHSDMRLPPAEFAQLIKRRQRQQQQQEYQELFRHMNQGDAGSLAPGLGGQSMTERQALPYQNADSYHHHHTSPQHLLQIRAQECISQVSSPTPTHSYAPQAALVHSESMEEECSCEGAKDGFPDRKSGNTLTKGCHDSPLLLSTGGPGDPESLLGTVNHAQELGIHPYRQPAAAFTRNKVSSRESVLGKCMDRSSPGQAMELPDHNGLGYPAHPSVSEHQRPRTLQRHHTIQNSDDAYVQLDNLPGMSLVAGKALSSARMSDAVLSQSSLMGSQQFQDGENEECGESLGGQEHPDLTDGSQHLNSSCYPSTCITDILLSYKHPEVSFSMEQAGV", "length": 1290, "header": "tr|A0ABI0P221-1|A0ABI0P221_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=SIK3 PE=3 SV=1 CANONICAL=V6F977-1" }, "locus": { "chromosome": "15", "start_pos": 27630660, "end_pos": 27514731, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152102.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152102.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105077.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105077.1" } ] } }, { "isoform_ac": "F1MXE2-1", "url": "https://www.uniprot.org/uniprotkb/F1MXE2/entry", "sequence": { "sequence": "MAAAAASGAGGAAGAGAGGAGPAGRLLPPPAPGPPAAPAAVPPAAGPPRPPAPASRGPVPARIGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLKKIFREVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVAAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICKHKWMKLGDADPNFDRLIAECQQLKEERQMDPLNEDVLLAMENMGLDKERTLQSLRSDAYDHYSAIYSLLCDRHKRHKTLRVGVPPGMPRTMGFQPPVNLQAEQAGTTMNISVPQVQLINPENQIVEPDGAVNVDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKLLPGFPGVNPQAPFLQVAPNVNFMHNLLPMQNLQPTGQLEYKEQSLLQPPTLQLLNGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEAVQRYLANRSKRHTLAMTNPTAEIPPDLQRQLGQQPFRSRVWPPHLVPDQHRSTYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLEKMGNNSSIKQLQQECEQLQKMYGGQIDERTLEKTQQQHMLYQQEQHHQILQQQIQDSICPPQPSPPLQAACENQPALLTHQLQRLRIQPSSPPPNHPNNHLFRQPSNSPPPMSSAMMQSHGATSSSQFQGFPSRSAIFQQQPENCSPPPSVALTCLGIQQPPQSQQVTIQVQEPVDMLSSMPGAAAASAGRGVSISPNTSQVQMQLRTSLMAALSYGHRPLSKQLSADSAEAHSLNVNRFSPANYDQAHLHPHLFSDQSRGSPSSYNPSSGAGLPPTQALKVPPLDQFPTFPPSAHQQPPHYTTSALQQALLSPTPPDYTRHQQVPHILQGLLSPRHSLTGHSDMRLPPAEFAQLIKRRQRQQQQQEYQELFRHMNQGDAGSLAPGLGGQSMTERQALPYQNADSYHHHHTSPQHLLQIRAQECISQVSSPTPTHSYAPQAALVHSESMEEECSCEGAKDGFPDRKSGNTLTKGCHDSPLLLSTGGPGDPESLLGTVNHAQELGIHPYRQPAAAFTRNKVSSRESVLGKCMDRSSPGQAMELPDHNGLGYPAHPSVSEHQRPRTLQRHHTIQNSDDAYVQLDNLPGMSLVAGKALSSARMSDAVLSQSSLMGSQQFQDGENEECGESLGGQEHPDLTDGSQHLNSSCYPSTCITDILLSYKHPEVSFSMEQAGV", "length": 1362, "header": "tr|F1MXE2-1|F1MXE2_BOVIN Computationally mapped isoform of Serine/threonine-protein kinase SIK3 OS=Bos taurus OX=9913 GN=SIK3 PE=3 SV=2 CANONICAL=V6F977-1" }, "locus": { "chromosome": "15", "start_pos": 27778086, "end_pos": 27514731, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020116.6", "url": "https://www.ensembl.org/id/ENSBTAT00000020116.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020116.5", "url": "https://www.ensembl.org/id/ENSBTAP00000020116.5" } ] } }, { "isoform_ac": "V6F977-1", "url": "https://www.uniprot.org/uniprotkb/V6F977/entry", "sequence": { "sequence": "MAAAAASGAGGAAGAGAGGAGPAGRLLPPPAPGPPAAPAAVPPAAGPPRPPAPASRGPVPARIGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLKKIFREVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVAAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICKHKWMKLGDADPNFDRLIAECQQLKEERQMDPLNEDVLLAMENMGLDKERTLQSLRSDAYDHYSAIYSLLCDRHKRHKTLRVGVPPGMPRTMGFQPPVNLQAEQAGTTMNISVPQVQLINPENQIVEPDGAVNVDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKLLPGFPGVNPQAPFLQVAPNVNFMHNLLPMQNLQPTGQLEYKEQSLLQPPTLQLLNGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEAVQSSTYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLEKMGNNSSIKQLQQECEQLQKMYGGQIDERTLEKTQQQHMLYQQEQHHQILQQQIQDSICPPQPSPPLQAACENQPALLTHQLQRLRIQPSSPPPNHPNNHLFRQPSNSPPPMSSAMMQSHGATSSSQFQGFPSRSAIFQQQPENCSPPPSVALTCLGIQQPPQSQQVTIQVQEPVDMLSSMPGAAAASAGRGVSISPNTSQVQMQLRTSLMAALSYGHRPLSKQLSADSAEAHSLNVNRFSPANYDQAHLHPHLFSDQSRGSPSSYNPSSGAGLPPTQALKVPPLDQFPTFPPSAHQQPPHYTTSALQQALLSPTPPDYTRHQQVPHILQGLLSPRHSLTGHSDMRLPPAEFAQLIKRRQRQQQQQEYQELFRHMNQGDAGSLAPGLGGQSMTERQALPYQNADSYHHHHTSPQHLLQIRAQECISQVSSPTPTHSYAPQAALVHSESMEEECSCEGAKDGFPDRKSGNTLTKGCHDSPLLLSTGGPGDPESLLGTVNHAQELGIHPYRQPAAAFTRNKVSSRESVLGKCMDRSSPGQAMELPDHNGLGYPAHPSVSEHQRPRTLQRHHTIQNSDDAYVQLDNLPGMSLVAGKALSSARMSDAVLSQSSLMGSQQFQDGENEECGESLGGQEHPDLTDGSQHLNSSCYPSTCITDILLSYKHPEVSFSMEQAGV", "length": 1314, "header": "tr|V6F977-1|V6F977_BOVIN Isoform 1 of Serine/threonine-protein kinase SIK3 OS=Bos taurus OX=9913 GN=SIK3 PE=3 SV=1 CANONICAL=V6F977-1" }, "locus": { "chromosome": "15", "start_pos": 27778086, "end_pos": 27514731, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066494.2", "url": "https://www.ensembl.org/id/ENSBTAT00000066494.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059537.1", "url": "https://www.ensembl.org/id/ENSBTAP00000059537.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1072, "start_aa": "Thr", "end_pos": 1072, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1072", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 585, "start_aa": "Thr", "end_pos": 585, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr585", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 955, "start_aa": "Thr", "end_pos": 955, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr955", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:506539", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:506539", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1T1S2-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "SIK3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVSSYNIKVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVAAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICKHKWMKLGDADPNFDRLIAECQQLKEERQMDPLNEDVLLAMEDMGLDKERTLQSLRSDAYDHYSAIYSLLCDRHKRHKTLRVGVPPSMPRAMAFQAPVNIQAEQAGTTMNISVPQVQLINPENQIVEPDGTVNLDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKLLPGFPGVNPQAPFLQVAPNMNFMHNLLPMQNLQPTGQLEYKEQSLLQPPTLQLLNGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEAVQRYLANRSKRHTLAMTNPTAEIPPDLQRQLGQQPFRSRVWPPHLVPDQHRSTYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLEKMGNNSSIKQLQQECEQLQKMYGGQIDERTLEKTQQQHMLYQQEQHHQILQQQIQDSICPPQPSPPLQAACENQPALLTHQLQRLRIQPSSPPPNHPNNHLFRQPSNSPPPMNSAMIQSHGAASPSQFQGFPSRSAVFQQQPENCSPPPNVALTCLGIQQPPQSQQVTIQVQEPVDMLSSMPGTAAGSAGRGVSVSPSASQVQMQHRTNLIAAFSYGHRPLSKQLSADSAEAHSLNVNRFSPANYDQAHLHPHLFSDQSRGSPSSYSPPTGVGFPPTQALKVPPLDQFPTFPPSAHPQSPHYTTSALQQALLSPTPPDYTRHQQVPHILQGLLSPRHSLTGHSDIRLPPAEFAQLIKRQQQQRQQQQQQQQEYQELLRHMNQGDAGSLAPGLGGQSMTERQALPYQNADSYHHHHHTSPQHLLQIRAQECISQASSASPTHAYAQQPALVHSESMEEECSCDGAKDGFPDRKSASTLAKGCHDSPLLLSTGGPGDPESLLGTVSHAQELGLHPYRQAAAAFPRNKVSSRESVIGNCMDRSSPGQAMELPDHNGLGYPAHPSVSEHHRPRTLQRHHTIQNSDDAYVQLDNLPGMSLVAGKALSSARMSDAVLSQSSLMGSQQFQDGENEECGEHLGAHEHADLTDGSQHLNSSCYPSTCITDILLSYKHPEVSFSMEQAGV", "length": 1247 }, "evidence": [ { "id": "V6F977", "url": "https://omabrowser.org/oma/group/V6F977/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6A0T3-1", "protein_name": "Serine/threonine-protein kinase SIK3", "gene_name": "Sik3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAAASGAGGVAVAGAGGAGPAGRLLPPPAAGPPAAPAAVPPAACPPRPTAPASRGSMAARIGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLKKIFREVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICRHRWMKLGDADPNFERLIAECQQLKEERQAEPLNDEVLLAMEDMGLDKERTLQSLRSDAYDHYSAIYSLLCDRHKKNKTLRPGALPSTPQAMTFQAPVNIQAEQTGTAMNISVPQVQLINPENQIIEPDGAVNLDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMDEMQKLLPGFPGANPQTPFLQVAPNMNFMHNLLPMQSLQPTGQLEYKEQSLLQPPTLQLLNGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEAVQSSTYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLERMGNSSSIKQLQQECEQLQKMYGGQVDERTLEKTQQQHMLYQQEQHHQILQQQIQDSICPPQPSPPLQAACENQPTLLTHQLQRLRIQPSSPPPNHPSNHLFRQPSNSPPPVSSAMISSHGATSPSQFQGLPSHGAIFQQQPENCSPPPSVALTCLGLQQASQSQPVTIQLQEPVDMLSNMAGTTAGSAGRGIPISPSASQIQMQHRTSLMAPFGYGHRPLSKQLSADSAEAHSLSMNRFSPANYDQAHLHPHLFSEQSRGPPSSYSPSTGVGFPPAQALRVPPLDQFPTFPPSAHQQPHYTTSALQQALLSPTPPDYTRHQQVPHILQGLLSPRHSLTGHSDIRLPPAEFAQLIKRQQQHRQQQQQQQQQQQQEYHELFRHMNQGDAVSLAPGLGGQNMTEHQALSYQNADSYHRHHTSPQHLLQIRAQDCISQGPLPTPTRGYARQSPLMHSESMEEDCLCEGVKEGFADKSSSTLTKGCHDSPLLLCTSGPGDPEPLLGTVSQARELGIHPYGHQPTATTFSRNKVPSRESVIGNCMERSSPGQAMELPDHNGLGYPARPLVSEHLRSRTLQRHHTIQNSDDAYVQLDTLPGMSLVAGKALSSARMSDAVLSQSSLMGSQQFQDEEDEECGVSLGHEHPALGDGSQHLNSRYPATCVTDIMLNHKHPEVSFSMEQAGV", "length": 1321 }, "evidence": [ { "id": "V6F977", "url": "https://omabrowser.org/oma/group/V6F977/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V1A7E9-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "SIK3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAAAAAAAASGAGGPPPAPRLPPAPPPPRPPGPARIGYYEIERTIGKGNFAVVKLATHLVTRAKVAIKIIDKTQLDDENLKKIFREVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVAAVNFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNIFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPSKRLSMDQICKHKWMKLGEADAEFDRLIAECQHLKTERQMEPLNEDVLLAMAEMGLDKERTIQSLRADAYDHYSAIYSLLCDRLKRHKNLRIAPSPSIPRTVTFPTSANIQQTEQAGNTMNINVPQVQLINPENQIVETDGTMNLDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKLLPGFPRVTPQAPFLQVTPNVNFMHNVLPRQNLQPTGQLEYKEQSLLQPPTLQLLNGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEAVQRYLANRSKRHTLAMTNPTAEIPPDLQRQLGQQSFRPRAWAPHLVPDQHRSIYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLEKMGNNSSIKQLQQECEQLQKMYGGHMDERTLEKTQQQHMLYQQEQHHQILHQQIQDCIRPPQPSPPLQAQCENQPALLTHQLQRLRIQPSSPPPNHPNNHLFRQPNSSPPPVSSSVLQPHGAASQSQFQGMPSHNTIFPQSGNCSPPPTMGLTCLALQQQSQAQQVTIQVQEPGDMVSNNLLQGASVAGQGMSSHTRGMSISPSANQIQMQHRANLMASLTYGHRQLSKQLSADSAESHSLNVYRNPPANYDQVHLHPHLFPEQPRVSPSNYSPSGGVGFPPAQQALKVPQLDQYPNFPQNAHQQQQHYTASALQQALLSPTPPDYSRHQQVPHILQGLLSPRHSLTGHTDMRLPQAEFAQLIKRRQQQQQQQQQQQEFQELFRHMSQGDAGNMGTSMGQSLSERQSLSLPYQSADTYHPQNSPQHLLKIRAQECIQQVPASVPPHGYVHQPALFHSESMEEDCACEGARDSFPDSKNSNTLTKGCHETPLLVNAGGHGDPESLLGTANHVQELGTHQYRHQPAAGFSRNKVPSRESVVGNCMDRSSPGQAMQVPDHNGLGYPARPASSEHPRPRTLQRHHTIQNSDDAYVQLDNLPGMSLMAGKALSSARMSDAVLSQSSLMASQQLRDRESDECGESLEGQEHPNLGDGNQHLNTSCYPSTCITDVLLSYKHPEVPFGMEQAGV", "length": 1349 }, "evidence": [ { "id": "V6F977", "url": "https://omabrowser.org/oma/group/V6F977/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q6P4S6-1", "protein_name": "Serine/threonine-protein kinase SIK3", "gene_name": "Sik3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAASGAGGVAVAGAGGAGPAGRLLPPPAAGPPAAPAAVPPAAVPARPTAPASRGSMAARIGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKSQLDEENLKKIFREVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICRHKWMKLGDADPNFDRLIAECQQLKEERQSDPLNDDVLLAMEDMGLDKERTLQSLRSDAYDHYSAIYSLLCDRHKKHKTLRPGALPSMPQAMTFQAPVNLQAEQTGTAMNLSVPQVQLINPENQIIEPDGAVNLDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKLLPGFPGVNPQGPFLQVAPNMNFTHNLLPMQSLQPTGQLEYKEQSLLQPPTLQLLNGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEAVQRYLANRSKRHTLAMTSPTAEIPPDLQRQLGQQSFRSRVWPPHLVPDQHRSTYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLEKMGNSSSIKQLQQECEQLQKMYGGQVDERTLEKTQQQHMLYQQEQHHQILQQQIQDSICPPQPSPPLQVACENQPALLTHQLQRLRIQPSSPPPNHPSNHLFRQPSNSPPPVSSAMITSHGATSPSQFQGLPSHGAIFQQQPENCSPPPSVALTCLGLQQASQSQPVTIQLQEPVDMLSNMAGTAAGSAGRSIPISPSASQIQIQHRASLMAPFSYGHRPLSKQLSADSAEAHSLNMNRFSPANYDQAHLHPHLFSDQSRGSPSSYSPSTGVGFPPTQALKVPPLDQFPTFPPSAQQQPPHYTTSALQQALLSPTPPDYPRHQQVPHILQGLLSPRHSLTGHSDIRLPPAEFAQLIKRQQQHRQQQQQQQQQQEYHELFRHMNQGDAVSLAPSLGGQNMTEQQALSYQNADSYHRHHTSPQHILQIRAQDCISQGPSPTPTHGYAHQPPLMHSESMEEDCLCEGLKEGFPDKSSSTLTKGCHNSPLLLCTSGPGDPEPLLGTVSQARELGIHPYGHQPTATTFSRNKVPSRESVLGNCLERSSPGQAMELPDHNGLGYPVRPLVSEHLRSRTLQRHHTIQNSDDAYVQLDTLPGMSLVAGKALSSARMSDAVLSQSSLMGSQQFQDEEDEECGVSLGHEHPGLGDGSQHLNSSRYPATCVTDIMLSHKHPEVSFSMEQAGV", "length": 1369 }, "evidence": [ { "id": "V6F977", "url": "https://omabrowser.org/oma/group/V6F977/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y2K2-5", "protein_name": "Serine/threonine-protein kinase SIK3", "gene_name": "SIK3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAAASGAGGAAGAGTGGAGPAGRLLPPPAPGSPAAPAAVSPAAGQPRPPAPASRGPMPARIGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLKKIFREVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICKHKWMKLGDADPNFDRLIAECQQLKEERQVDPLNEDVLLAMEDMGLDKEQTLQSLRSDAYDHYSAIYSLLCDRHKRHKTLRLGALPSMPRALAFQAPVNIQAEQAGTAMNISVPQVQLINPENQIVEPDGTLNLDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKLLPGFPGVNPQAPFLQVAPNVNFMHNLLPMQNLQPTGQLEYKEQSLLQPPTLQLLNGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEAVQSSTYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLEKMGNNSSIKQLQQECEQLQKMYGGQIDERTLEKTQQQHMLYQQEQHHQILQQQIQDSICPPQPSPPLQAACENQPALLTHQLQRLRIQPSSPPPNHPNNHLFRQPSNSPPPMSSAMIQPHGAASSSQFQGLPSRSAIFQQQPENCSSPPNVALTCLGMQQPAQSQQVTIQVQEPVDMLSNMPGTAAGSSGRGISISPSAGQMQMQHRTNLMATLSYGHRPLSKQLSADSAEAHSLNVNRFSPANYDQAHLHPHLFSDQSRGSPSSYSPSTGVGFSPTQALKVPPLDQFPTFPPSAHQQPPHYTTSALQQALLSPTPPDYTRHQQVPHILQGLLSPRHSLTGHSDIRLPPTEFAQLIKRQQQQRQQQQQQQQQQEYQELFRHMNQGDAGSLAPSLGGQSMTERQALSYQNADSYHHHTSPQHLLQIRAQECVSQASSPTPPHGYAHQPALMHSESMEEDCSCEGAKDGFQDSKSSSTLTKGCHDSPLLLSTGGPGDPESLLGTVSHAQELGIHPYGHQPTAAFSKNKVPSREPVIGNCMDRSSPGQAVELPDHNGLGYPARPSVHEHHRPRALQRHHTIQNSDDAYVQLDNLPGMSLVAGKALSSARMSDAVLSQSSLMGSQQFQDGENEECGASLGGHEHPDLSDGSQHLNSSCYPSTCITDILLSYKHPEVSFSMEQAGV", "length": 1321 }, "evidence": [ { "id": "V6F977", "url": "https://omabrowser.org/oma/group/V6F977/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "V6F977", "url": "https://www.uniprot.org/uniprotkb/V6F977" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "V6F977", "url": "https://www.uniprot.org/uniprotkb/V6F977" } ], "pmid": "" }, { "name": "tau-protein kinase activity", "id": "GO:0050321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050321", "evidence": [ { "database": "UniProtKB", "id": "V6F977", "url": "https://www.uniprot.org/uniprotkb/V6F977" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "V6F977", "url": "https://www.uniprot.org/uniprotkb/V6F977" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "V6F977", "url": "https://www.uniprot.org/uniprotkb/V6F977" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "V6F977", "url": "https://www.uniprot.org/uniprotkb/V6F977" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "V6F977", "url": "https://www.uniprot.org/uniprotkb/V6F977" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1284, "end_pos": 1286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" }, { "start_pos": 644, "end_pos": 646, "annotation": "n_glycosylation_sequon" }, { "start_pos": 645, "end_pos": 647, "annotation": "n_glycosylation_sequon" }, { "start_pos": 784, "end_pos": 786, "annotation": "n_glycosylation_sequon" }, { "start_pos": 838, "end_pos": 840, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", 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"id": "A0A3Q1MHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHM3" } ] } ] }, { "uniprot_ac": "A0A3Q1MI36", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MI36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MI36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI36" } ] } ] }, { "uniprot_ac": "A0A3Q1MKC7", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] } ] }, { "uniprot_ac": "A0A3Q1MLK5", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] } ] }, { "uniprot_ac": "A0A3Q1MNB4", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] } ] }, { "uniprot_ac": "A0A3Q1MRR6", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] } ] }, { "uniprot_ac": "A0A3Q1MRW3", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] } ] }, { "uniprot_ac": "A0A3Q1MS69", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] } ] }, { "uniprot_ac": "A0A3Q1MUZ6", "gene_name": "MARK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MW77", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] } ] }, { "uniprot_ac": "A0A3Q1MXI5", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] } ] }, { "uniprot_ac": "A0A3Q1N4A7", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] } ] }, { "uniprot_ac": "A0A3Q1N707", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] } ] }, { "uniprot_ac": "A0A3Q1N860", "gene_name": "RPS6KL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] } ] }, { "uniprot_ac": "A0A3Q1N9F5", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] } ] }, { "uniprot_ac": "A0A3Q1NBC4", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": 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"uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] } ] }, { "uniprot_ac": "Q3SYZ2", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] } ] }, { "uniprot_ac": "Q3SZJ2", "gene_name": "RIPK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": 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"activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] } ] }, { "uniprot_ac": "Q3T0P6", "gene_name": "PGK1", "activity": [ { "ec_number": "2.7.2.3", "activity": "(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP.", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.2.3", "activity": "", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": 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"Protein Classification", "Other" ] }, { "id": "PF14438", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14438", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010817742", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010817742", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MAS9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MAS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAS9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MR95", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MR95-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR95-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJ59", "url": "https://www.uniprot.org/uniprotkb/E1BJ59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJ59-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ59-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLKPQPPQQTSQPQQPPPTQQAVARRPPGGTSPPNGGLPGSLASTSAPPGPPAAASPCLGPAAAAGSGLRRGAEGILAPQPPAPQQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNNSRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKVSEPAGGPRREDIVDTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDDYDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLAREIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLAAREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSSRPSGEASVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPMGSAVPTSSASIPVTSAVGDPGVGSVSPASPKISLAPTDVKELPAKEPGRTLESQELSRIAAKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPETSLDPFPPRILKEEAKGKEKEVDGLLASEPLGSPVSSKAESVSDKEDKLPLPAAGGAEGPEQPPAPCPSQTGSPPVGLIKGDDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPPSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHAHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRIREFSLAGGIWHGRADGLQVGQDARVLGGE", "length": 1078, "header": "tr|E1BJ59-1|E1BJ59_BOVIN Isoform 1 of Ataxin 2 like OS=Bos taurus OX=9913 GN=ATXN2L PE=3 SV=2 CANONICAL=E1BJ59-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MAS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAS9/entry", "sequence": { "sequence": "MERGARLTVWPMGREGLGSELLPPRPSLASRRGAGWAGGRKEGLRGLRAGNLQRARSSRTCARMLCLMTRPFSSLGGQSTGKGPPQSPVFEGVYNNSRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKVSEPAGGPRREDIVDTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDDYDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLAREIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLAAREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSSRPSGEASVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPMGSAVPTSSASIPVTSAVGDPGVGSVSPASPKISLAPTDVKELPAKEPGRTLESQELSRIAAKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPETSLDPFPPRILKEEAKGKEKEVDGLLASEPLGSPVSSKAESVSDKEDKLPLPAAGGAEGPEQPPAPCPSQTGSPPVGLIKGDDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPPSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHAHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRIREFSLAGGIWHGRADGLQVGQDARVLGGE", "length": 1053, "header": "tr|A0A3Q1MAS9-1|A0A3Q1MAS9_BOVIN Computationally mapped isoform of Ataxin 2 like OS=Bos taurus OX=9913 GN=ATXN2L PE=3 SV=2 CANONICAL=E1BJ59-1" }, "locus": { "chromosome": "25", "start_pos": 25984898, "end_pos": 25975035, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072038.2", "url": "https://www.ensembl.org/id/ENSBTAT00000072038.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065709.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065709.2" } ] } }, { "isoform_ac": "A0A3Q1MR95-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR95/entry", "sequence": { "sequence": "MLKPQPPQQTSQPQQPPPTQQAVARRPPGGTSPPNGGLPGSLASTSAPPGPPAAASPCLGPAAAAGSGLRRGAEGILAPQPPAPQQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNNSRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKVSEPAGGPRREDIVDTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDDYDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLAREIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLAAREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSSRPSGEASVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPMGSAVPTSSASIPVTSAVGDPGVGSVSPASPKISLAPTDVKELPAKEPGRTLESQELSRIAAKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPETSLDPFPPRILKEEAKGKEKEVDGLLASEPLGSPVSSKAESVSDKEDKLPLPAAGGAEGPEQPPAPCPSQTGSPPVGLIKGDDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPPSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHAHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRILCRVGRSHSRRRQGLAPGSVLCFPPSSLSCDPAAPLPTASPALSDPDCLLT", "length": 1100, "header": "tr|A0A3Q1MR95-1|A0A3Q1MR95_BOVIN Computationally mapped isoform of Ataxin 2 like OS=Bos taurus OX=9913 GN=ATXN2L PE=3 SV=1 CANONICAL=E1BJ59-1" }, "locus": { "chromosome": "25", "start_pos": 25985608, "end_pos": 25974820, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077477.2", "url": "https://www.ensembl.org/id/ENSBTAT00000077477.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056890.1", "url": "https://www.ensembl.org/id/ENSBTAP00000056890.1" } ] } }, { "isoform_ac": "E1BJ59-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ59/entry", "sequence": { "sequence": "MLKPQPPQQTSQPQQPPPTQQAVARRPPGGTSPPNGGLPGSLASTSAPPGPPAAASPCLGPAAAAGSGLRRGAEGILAPQPPAPQQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNNSRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKVSEPAGGPRREDIVDTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDDYDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLAREIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLAAREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSSRPSGEASVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPMGSAVPTSSASIPVTSAVGDPGVGSVSPASPKISLAPTDVKELPAKEPGRTLESQELSRIAAKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPETSLDPFPPRILKEEAKGKEKEVDGLLASEPLGSPVSSKAESVSDKEDKLPLPAAGGAEGPEQPPAPCPSQTGSPPVGLIKGDDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPPSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHAHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRIREFSLAGGIWHGRADGLQVGQDARVLGGE", "length": 1078, "header": "tr|E1BJ59-1|E1BJ59_BOVIN Isoform 1 of Ataxin 2 like OS=Bos taurus OX=9913 GN=ATXN2L PE=3 SV=2 CANONICAL=E1BJ59-1" }, "locus": { "chromosome": "25", "start_pos": 25985608, "end_pos": 25975035, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000045493.4", "url": "https://www.ensembl.org/id/ENSBTAT00000045493.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000042875.3", "url": "https://www.ensembl.org/id/ENSBTAP00000042875.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 19, "start_aa": "Thr", "end_pos": 19, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr19", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:539507", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539507", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JYE0-1", "protein_name": "Ataxin 2-like", "gene_name": "Atxn2l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKPQPPQQTSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLPATAAPPGPPTVVSPCLGPAAAAGSGLRRGAESILAAPAPQQHQERPGAVAIGSVRGQTTGKGPPQSPVFEGVYNNSRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIVDTMVFKPSDVLLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDDYDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLAREIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLVSREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGGKTLSSPNNRPSGEASVPPTSAVGRMYPPRSPKSAAPAPVSASCPEPPIGSAVASSASIPVTSSVVDPGAGSISPASPKLSLAPTDVKELPTKEPSRSLEAQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSSETGLDPFPSRILKEEAKGKEKEVDGLLTSDPMGSPVSSKAESILDKEDKVPLAAVAGSEGPEQLQPPCPSQTGSPPVGLIKGDDKEEGPVTEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHGHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHPHQQLPHGFTNMAHVTQAHVQTGVTAAPPPHPGAPHPPQVMLLHPPQGHGGPPQGAVPPSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRILCRVGRSHSRRRQGLAPGSVLCFPPSSLSCDPAAPLPTASPALSDPDCLLT", "length": 1096 }, "evidence": [ { "id": "E1BJ59", "url": "https://omabrowser.org/oma/group/E1BJ59/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QA42-1", "protein_name": "Ataxin-2-like protein", "gene_name": "atxn2l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSFRRQNQPGPGGRKTSNGTSGSMASSVPGSNSNRPNPGRNRNSVKTPSQSPPVFEGVYNNSRMLHFLTAVVGSRCDVMVKNGSLYEGIFKTLSSRCELAVDAVHKVKNEEGDGGGGGGTAVHPRKEEITDTMIFGPSDLVTMICRDVDLNYATRDTFTDSAIGSSRLNGDHREKVLQRWDGGDSNGENFDLDADTANGWDASEMFRFNEETYGVKSTYDSSLSMYTVPLERGSSEGFRQREARAARLANEIEASSQYRHRVALENDEGRTDEDKFSAVVRDREREAAERERGRDSPGFSSAGSREGKYIPPQRAREREMGVSGRGERGGAVSTLPNRTNRPGPSSSSPRPLPSANSQALPPTDRNSSLSVRGGFSTHQSQSSTPTQSRPSEPGHSSPPSPHTLSHSLSHPQSLSDVARPVNGVSPKSQRTGQTNRNMRTSNSHSSPTVSRSPKPDAPPQDPLLTGSYLDPSSKPVGPTPLFPVDVNEILSKERMESPVGPQEGKSNKIPSVQQRSQISEELRKFGNTFRLQQNPKTLPTESTQANPAHNTQTDPAAPTEAKPAPPTTPNTELSAEERSRETNPEGPVTSTPPPATSISAPSGIGMQNPPAEGQTAGAPQPARTPGSEDGKPEAPERSEGMTDQVKKSTLNPNAKEFNPTKAPLSMVKPSATPTPPRPTPPSPTVVLQTQPGQGAVYNPQYLSYVSQVPIQIQGHSVQPQIPYSYMTAVSQGKYPRTKGSVVTPRPDHSSSAPPMIQAASAAGPPLVASPYPPSYLQYNQVIPAMPHYPGHQVYSMLQGGPRMLGSGGHPQALGPPGPQYPGQTEGPSAPQQGMYAPQSFSHHSGSIHPQPSSTPTGSQPPPQHPAPSPGQSGQSGPQPQSLYHSGPLSAPTPPNLPPGHSSPQASYSLQGYSLPGHQPLPHPYSSLGQLTQAHVPGALSGPHHTGGHGPPPVMLLHAAPQQGSGPQHGPPPQQGAHQHFTYLGPQVPVQAHNPQQIPYHPSGN", "length": 1004 }, "evidence": [ { "id": "E1BJ59", "url": "https://omabrowser.org/oma/group/E1BJ59/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q7TQH0-1", "protein_name": "Ataxin-2-like protein", "gene_name": "Atxn2l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLKPQPPQQTSQPQQPPPTQQAVARRSPGGTSPPNGGLPGPLTATAAPPGPPAAVSPCLGPAAAAGSGLRRGAESILAASAPPQHQERPGAVAIGSVRGQTTGKGPPQSPVFEGVYNNSRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIVDTMVFKPSDVLLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDDYDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLAREIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLVSREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGEASVPPTSAALPFLPVGRMYPPRSPKSAAPAPVSASCPEPPIGSAVASSASIPVTSSVVDPGAGSISPASPKLSLTPTDVKELPTKEPSRNLEAQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPETGLDPFPSRILKEEAKGKEKEVDGLLTSDPMGSPVSSKTESILDKEDKVPMAGVGGTEGPEQLPAPCPSQTGSPPVGLIKGDEKEEGPVTEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPAAEQPTPQALYATVHQSYPHHATQLHGHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHPHQQLPHGFTNMAHVTQAHVQTGVTAAPPPHPGAPHPPQVMLLHPPQGHGGPPQGAVPPSGVPALSASTPSPYPYIGHPQVQSHPSQQLPFHPPGN", "length": 1049 }, "evidence": [ { "id": "E1BJ59", "url": "https://omabrowser.org/oma/group/E1BJ59/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8SWR8-1", "protein_name": "Ataxin-2 homolog", "gene_name": "Atx2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNNNSKRKTRPTGGGASGGISRYNSNDNSLRPTNNKAGAGGGNGGAAVRPSAQGVYNNTFFMHSATALVGSVVEVRLRSGNIYEGVFRTFSGNFDIALELPACIKSKNLPEEGKVPKHIIFPADTVVTIVAKDFDSQYATAGAFQTDGAISDKCNGARPDEKELEPWDSGANGDIDIELDSAANGWDPNEMFRKNENTFGVTSTFDDSLASYTVPLDKGDSLEFKEAEAKAEKLAAEIENNPTCRDRLDLENGDEEALFAAVERPSTEQDQRGDRGDRERNDRDREREERDRDRDRDRGNKPRGAGDFQLRETMSSDRYITKQTRSITGPQLSHVGMSSQGSGRDRDTRGDGSMMMQSGGGSGQGGSTQSTAALMLAGGLKGVGPAPSANASADSSSKYSGGSMVKRKTVPQGGKVMRNNVPTGGSNVSVSQGGNGNSVGQNKGGYQPSMGMPSQYSYQGNSQIMHGSSQYRNQSHMGGANKLNGDSNANTNKPLPQRQMRQYQGSQSNSSLNYGGEPQSLGKPVHGSHGGHPGQNSNSPPLQTAGPQQQQQQQQQQQQQQQQQQPPQQQQHQNIQPQGQNTQPARQVRTRDNQMQELRQFGQDFQLAPSNTSPPQQQQQQQQQQQQHQVQQQQQRALQQSASPPQQQQQQQQQQQHVVLHQVPQTHLHQAALSQPHYVPQQQPQQAPLPQQQHVPHHMQQKAQQQQLVETQHQHVQKQHQSQPQVQQPPPQLLQDPSQQPLPIYHTMPPPQTSPVVVTSPVLLEQPPPQPMPVVQQQQTQQLATPKPEVSPAPPSSNTTTPTGIASTPTAGVIASAGSEKTTPAAPTPTSNSATVPTGTAATAGGATGTTPVVKKHVLNPSAKPFTPRGPSTPNPSRPHTPQTPVPMTNIYTTTGGHVPPAANQPIYVMQPQHPFPPQTHPQAGQPPRLRRSNYPPMAASQMHVSASAATGQPLITAGPIPQFIQYGHAPHQQQFQSHTYAPMQMRVYPDQPQQLQFMTQTPQSTTPSPGQPHQQFHPPPQPSPAGGGPQPAFTPPTQAATYQLMCVHPQSLLANHYFPPPTPQHPQQNQQQYQIVMQQHQPQ", "length": 1084 }, "evidence": [ { "id": "E1BJ59", "url": "https://omabrowser.org/oma/group/E1BJ59/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8WWM7-1", "protein_name": "Ataxin-2-like protein", "gene_name": "ATXN2L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNNSRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIVDTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDDYDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLAREIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRIREFSLAGGIWHGRAEGLQVGQDARVLGGE", "length": 1075 }, "evidence": [ { "id": "E1BJ59", "url": "https://omabrowser.org/oma/group/E1BJ59/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "E1BJ59", "url": "https://www.uniprot.org/uniprotkb/E1BJ59" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "E1BJ59", "url": "https://www.uniprot.org/uniprotkb/E1BJ59" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA metabolic process", "id": "GO:0016071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016071", "evidence": [ { "database": "UniProtKB", "id": "E1BJ59", "url": 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"E1BD67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BD67" }, { "id": "PF28174", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28174" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAAL1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 154, "end_pos": 415, "start_aa": "Ile", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BEJ7-1", "uniprot_ac": "E1BEJ7", "uniprot_id": "E1BEJ7_BOVIN", "mass": { "chemical_mass": 86555.0, "monoisotopic_mass": 86555.0 }, "refseq": { "ac": "NP_001179877", "name": "host cell factor 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179877" }, "gene_names": [ { "name": "HCFC2", "type": "recommended", "evidence": [ { "id": "E1BEJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEJ7" } ] }, { "name": "HCFC2", "type": "synonym", "evidence": [ { "id": "NP_001179877", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179877" } ] } ], "protein_names": [ { "name": "Host cell factor 2", "type": "recommended", "evidence": [ { "id": "E1BEJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEJ7/entry#names_and_taxonomy" } ] }, { "name": "C2 factor", "type": "synonym", "evidence": [ { "id": "E1BEJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEJ7/entry#names_and_taxonomy" } ] }, { "name": "host cell factor 2", "type": "synonym", "evidence": [ { "id": "NP_001179877", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179877" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BEJ7", "url": "https://www.uniprot.org/uniprotkb/E1BEJ7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HCFC2", "url": "https://www.uniprot.org/uniprotkb/E1BEJ7", "locus": { "chromosome": "5", "start_pos": 67761619, "end_pos": 67711441, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020933", "url": "https://www.ensembl.org/id/ENSBTAG00000020933" } ] } } ], "crossref": [ { "id": "E1BEJ7", "url": "https://alphafold.ebi.ac.uk/entry/E1BEJ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020933", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020933", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "505341", "url": "https://www.ncbi.nlm.nih.gov/gene/505341", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011043", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011043", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:505341", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505341", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VFKTLYC", "url": "https://omabrowser.org/oma/group/VFKTLYC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LXN7", "url": "https://www.orthodb.org/?gene=A0A3Q1LXN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BEJ7", "url": "https://www.orthodb.org/?gene=E1BEJ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46003:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46003:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13854", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13854", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9772755", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9772755", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179877", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179877", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LXN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LXN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXN7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJ49", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJ49-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TE25", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TE25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TE25-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TE25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWX1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWX1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWX1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P033", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P033", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P033-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P033-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEJ7", "url": "https://www.uniprot.org/uniprotkb/E1BEJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEJ7-1", "url": "https://www.uniprot.org/uniprotkb/E1BEJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPSLLNWRRVSSFTGPVPRARHGHRAVAIRELMIIFGGGNEGIADELHVYNTVTNQWFLPAVRGDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNELYELQASRWLWKKVKPHPPSSGLPPCPRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGIVPSPRESHTAVIYCKRDSGSPKMYVFGGMCGARLDDLWQLDLETMSWSKPETKGTVPLPRSLHTASVIGNKMYIFGGWVPHKGENIETSPHDCEWRCTSSFSYLNLDTAEWTTLVSDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSGRDGYKKALNSQVCCKDLWYLDTEKPPAPSQVQLIKATTNSFHVKWDEVPTVEGYLLQLNTDLPYQAVSSDPSASPNMQGVRMDPHRQGSNSIIPNSISDIVNSVKSEHTAVKGTSVKNKPDIKASTDSNASLHSSLAANASNHNSCVVDMLRKNEGPHTSANIGVLSSCLDLRTVIPETSVSSTVSSAQTMVTQQTIKTESSSTNGAVVKDETSLTTFSTKAEVDETCALPATKISRVEAHAATMPFSKETPSNPVAMVKAGERQWCDVGIFKNNTALVSQFYLLPKGKQSISKIGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRISKNVEGIHLSWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRPAIVFRISAKNEKGYGPATQVRWLQGNNKKAPLN", "length": 792, "header": "tr|E1BEJ7-1|E1BEJ7_BOVIN Isoform 1 of Host cell factor 2 OS=Bos taurus OX=9913 GN=HCFC2 PE=4 SV=1 CANONICAL=E1BEJ7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LXN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXN7/entry", "sequence": { "sequence": "MAAPSLLNWRRVSSFTGPVPRARHGHRAVAIRELMIIFGGGNEGIADELHVYNTVTNQWFLPAVRGDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNELYELQASRWLWKKVKPHPPSSGLPPCPRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGIVPSPRESHTAVIYCKRDSGSPKMYVFGGMCGARLDDLWQLDLETMSWSKPETKGTVPLPRSLHTASVIGNKMYIFGGWVPHKGENIETSPHDCEWRCTSSFSYLNLDTAEWTTLVSDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSGRDGYKKALNSQVCCKDLWYLDTEKPPAPSQVQLIKATTNSFHVKWDEVPTVEGYLLQLNTDLPYQAVSSDPSASPNMQGVRMDPHRQGSNSIIPNSISDIVNSVKSEHTAVKGTSVKNKPDIKASTDSNASLHSSLAANASNHNSCVVDMLRKNEGPHTSANIGVLSSCLDLRTVIPETSVSSTVSSAQTMVTQQTIKTESSSTNGAVVKDETSLTTFSTKAEVDETCALPATKISRVEAHAATMPFSKETPSNPVAMVKAGERQWCDVGIFKNNTALVSQFYLLPKGKQSISKIGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRISKNVEGIHLSWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRPAIVFRISAKNEKGYGPATQVRWLQGISWFHCLFESRINI", "length": 798, "header": "tr|A0A3Q1LXN7-1|A0A3Q1LXN7_BOVIN Computationally mapped isoform of Host cell factor 2 OS=Bos taurus OX=9913 GN=HCFC2 PE=4 SV=2 CANONICAL=E1BEJ7-1" }, "locus": { "chromosome": "5", "start_pos": 67754754, "end_pos": 67711448, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081561.3", "url": "https://www.ensembl.org/id/ENSBTAT00000081561.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061977.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061977.2" } ] } }, { "isoform_ac": "A0AAA9SJ49-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ49/entry", "sequence": { "sequence": "MAAPSLLNWRRVSSFTGPVPRARHGHRAVAIRELMIIFGGGNEGIADELHVYNTVTNQWFLPAVRGDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNELYELQASRWLWKKVKPHPPSSGLPPCPRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGIVPSPRESHTAVIYCKRDSGSPKMYVFGGMCGARLDDLWQLDLETMSWSKPETKGTVPLPRSLHTASVIGNKMYIFGGWVPHKGENIETSPHDCEWRCTSSFSYLNLDTAEWTTLVSDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSGRDGYKKALNSQVCCKDLWYLDTEKPPAPSQVQLIKATTNSFHVKWDEVPTVEGYLLQLNTDLPYQAVSSDPSASPNMQGVRMDPHRQGSNSIIPNSISDIVNSVKSEHTAVKGTSVKNKPDIKASTDSNASLHSSLAANASNHNSCVVDMLRKNEGPHTSANIGVLSSCLDLRTVIPETSVSSTVSSAQTMVTQQTIKTESSSTNGAVVKDETSLTTFSTKAEVDETCALPATKISRVEAHAATMPFSKETPSNPVAMVKAGERQWCDVGIFKNNTALVSQFYLLPKGKQSISKIGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRISKNVEGIHLSWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRPAIVFRISAKNEKGYGPATQVRWLQDI", "length": 785, "header": "tr|A0AAA9SJ49-1|A0AAA9SJ49_BOVIN Computationally mapped isoform of Host cell factor 2 OS=Bos taurus OX=9913 GN=HCFC2 PE=4 SV=1 CANONICAL=E1BEJ7-1" }, "locus": { "chromosome": "5", "start_pos": 67760934, "end_pos": 67711448, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000134260.1", "url": "https://www.ensembl.org/id/ENSBTAT00000134260.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082598.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082598.1" } ] } }, { "isoform_ac": "A0AAA9TE25-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TE25/entry", "sequence": { "sequence": "MAAPSLLNWRRVSSFTGPVPRARHGHRAVAIRELMIIFGGGNEGIADELHVYNTVTNQWFLPAVRGDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNELYELQASRWLWKKVKPHPPSSGLPPCPRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGIVPSPRESHTAVIYCKRDSGSPKMMYIFGGWVPHKGENIETSPHDCEWRCTSSFSYLNLDTAEWTTLVSDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSGRDGYKKALNSQVCCKDLWYLDTEKPPAPSQVQLIKATTNSFHVKWDEVPTVEGYLLQLNTDLPYQAVSSDPSASPNMQGVRMDPHRQGSNSIIPNSISDIVNSVKSEHTAVKGTSVKNKPDIKASTDSNASLHSSLAANASNHNSCVVDMLRKNEGPHTSANIGVLSSCLDLRTVIPETSVSSTVSSAQTMVTQQTIKTESSSTNGAVVKDETSLTTFSTKAEVDETCALPATKISRVEAHAATMPFSKETPSNPVAMVKAGERQWCDVGIFKNNTALVSQFYLLPKGKQSISKIGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRISKNVEGIHLSWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRPAIVFRISAKNEKGYGPATQVRWLQGNNKKAPLN", "length": 744, "header": "tr|A0AAA9TE25-1|A0AAA9TE25_BOVIN Computationally mapped isoform of Host cell factor C2 OS=Bos taurus OX=9913 GN=HCFC2 PE=4 SV=1 CANONICAL=E1BEJ7-1" }, "locus": { "chromosome": "5", "start_pos": 67753557, "end_pos": 67711448, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000088920.1", "url": "https://www.ensembl.org/id/ENSBTAT00000088920.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095024.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095024.1" } ] } }, { "isoform_ac": "A0ABI0NWX1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWX1/entry", "sequence": { "sequence": "MAAPSLLNWRRVSSFTGPVPRARHGHRAVAIRELMIIFGGGNEGIADELHVYNTVTNQWFLPAVRGDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNELYELQASRWLWKKVKPHPPSSGLPPCPRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGIVPSPRESHTAVIYCKRDSGSPKMYVFGGMCGARLDDLWQLDLETMSWSKPETKGTVPLPRSLHTASVIGNKMYIFGGWVPHKGENIETSPHDCEWRCTSSFSYLNLDTAEWTTLVSDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSGRDGYKKALNSQVCCKDLWYLDTEKPPAPSQVQLIKATTNSFHVKWDEVPTVEGYLLQLNTDLPYQAVSSDPSASPNMQGVRMDPHRQGSNSIIPNSISDIVNSVKSEHTAVKGTSVKNKPDIKASTDSNASLHSSLAANASNHNSCVVDMLRKNEGPHTSANIGVLSSCLDLRTVIPETSVSSTVSSAQTMVTQQTIKTESSSTNGAVVKDETSLTTFSTKAEVDETCALPATKISRVEAHAATMPFSIGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRISKNVEGIHLSWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRPAIVFRISAKNEKGYGPATQVRWLQGNNKKAPLN", "length": 746, "header": "tr|A0ABI0NWX1-1|A0ABI0NWX1_BOVIN Computationally mapped isoform of Host cell factor C2 OS=Bos taurus OX=9913 GN=HCFC2 PE=4 SV=1 CANONICAL=E1BEJ7-1" }, "locus": { "chromosome": "5", "start_pos": 67753557, "end_pos": 67711448, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154837.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154837.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106264.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106264.1" } ] } }, { "isoform_ac": "A0ABI0P033-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P033/entry", "sequence": { "sequence": "MAAPSLLNWRRVSSFTGPVPRARHGHRAVAIRELMIIFGGGNEGIADELHVYNTVTNQWFLPAVRGDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNELYELQASRWLWKKVKPHPPSSGLPPCPRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGIVPSPRESHTAVIYCKRDSGSPKMYVFGGMCGARLDDLWQLDLETMSWSKPETKGTVPLPRSLHTASVIGNKMYIFGGWVPHKGENIETSPHDCEWRCTSSFSYLNLDTAEWTTLVSDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSGRDGYKKALNSQVCCKDLWYLDTEKPPAPSQVQLIKATTNSFHVKWDEVPTVEGYLLQLNTDLPYQAVSSDPSASPNMQGVRMDPHRQGSNSIIPNSISDIVNSVKSEHTAVKGTSVKNKPDIKASTDSNASLHSSLAANASNHNSCVVDMLRKNEGPHTSANIGVLSSCLDLRTVIPETSVSSTVSSAQTMVTQQTIKTESSSTNGAVVKDETSLTTFSTKAEVDETCALPATKISRVEAHAATMPFSKETPSNPVAMVKAGERQWCDVGIFKNNTALVSQFYLLPKGKQSISKIGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRISKNVEGIHLSWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRPAIVFRISAKNEKGYGPATQVRWLQGLPRPRTGGKIDRNESQRTTFSHFICFRFNCCLL", "length": 817, "header": "tr|A0ABI0P033-1|A0ABI0P033_BOVIN Computationally mapped isoform of Host cell factor 2 OS=Bos taurus OX=9913 GN=HCFC2 PE=4 SV=1 CANONICAL=E1BEJ7-1" }, "locus": { "chromosome": "5", "start_pos": 67792939, "end_pos": 67711448, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140093.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140093.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104125.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104125.1" } ] } }, { "isoform_ac": "E1BEJ7-1", "url": "https://www.uniprot.org/uniprotkb/E1BEJ7/entry", "sequence": { "sequence": "MAAPSLLNWRRVSSFTGPVPRARHGHRAVAIRELMIIFGGGNEGIADELHVYNTVTNQWFLPAVRGDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNELYELQASRWLWKKVKPHPPSSGLPPCPRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGIVPSPRESHTAVIYCKRDSGSPKMYVFGGMCGARLDDLWQLDLETMSWSKPETKGTVPLPRSLHTASVIGNKMYIFGGWVPHKGENIETSPHDCEWRCTSSFSYLNLDTAEWTTLVSDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSGRDGYKKALNSQVCCKDLWYLDTEKPPAPSQVQLIKATTNSFHVKWDEVPTVEGYLLQLNTDLPYQAVSSDPSASPNMQGVRMDPHRQGSNSIIPNSISDIVNSVKSEHTAVKGTSVKNKPDIKASTDSNASLHSSLAANASNHNSCVVDMLRKNEGPHTSANIGVLSSCLDLRTVIPETSVSSTVSSAQTMVTQQTIKTESSSTNGAVVKDETSLTTFSTKAEVDETCALPATKISRVEAHAATMPFSKETPSNPVAMVKAGERQWCDVGIFKNNTALVSQFYLLPKGKQSISKIGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRISKNVEGIHLSWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRPAIVFRISAKNEKGYGPATQVRWLQGNNKKAPLN", "length": 792, "header": "tr|E1BEJ7-1|E1BEJ7_BOVIN Isoform 1 of Host cell factor 2 OS=Bos taurus OX=9913 GN=HCFC2 PE=4 SV=1 CANONICAL=E1BEJ7-1" }, "locus": { "chromosome": "5", "start_pos": 67753557, "end_pos": 67711448, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027882.6", "url": "https://www.ensembl.org/id/ENSBTAT00000027882.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027882.5", "url": "https://www.ensembl.org/id/ENSBTAP00000027882.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:505341", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505341", "resource": "KEGG Pathway" }, { "id": "R-BTA-9772755", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9772755", "resource": "Reactome", "description": "Formation of WDR5-containing histone-modifying complexes" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SRK9-1", "protein_name": "Host cell factor 2", "gene_name": "HCFC2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAPSLLNWRRVSSFTGPVPRARHGHRAVAIRELMIIFGGGNEGIADELHVYNTVTNQWFLPAVRGDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNELYELQASRWLWRKVKPHPPSSGLPPCPRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGIVPSPRESHTAVIYCRRDSGSPKMYVFGGMCGARLDDLWQLDLETMSWSKPETKGTVPLPRSLHTASVIGNKMYIFGGWVPHKGENIEASPHDCEWRCTSSFSYLNLDTAEWTTLVSDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSGRDGYKKALNSQVCCKDLWYLDTEKPPAPSQVQLIKATTNSFHVKWDEVPTVEGYLLQLNTDLPYQAPSSDSSASPNMQGVRMDPHRQGSNSIIPNSISDTMNSTKSEHTAMKGTSVKNKPDLKASTDSSAILHSSLATNASNHNSSVVDMLRKSEGPHTSADIGALSSCLDLRTVIPETSVSSTVSSAQTMVTQQTIKTESSSTNGAVVKDETSLTTFSTKSEVDETCALPAAKISRVETRAAATPFSKETTSNPVATVKAGERQWCDVGIFKNNTALVSQFYLLPKGKQSISKIGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRISKNVDGIHLSWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMKIYCGLKTSCIVTAGQLANAHIDYTSRPAIVFRISAKNEKGYGPATQVRWLQGNNKKAPLN", "length": 792 }, "evidence": [ { "id": "E1BEJ7", "url": "https://omabrowser.org/oma/group/E1BEJ7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5RKG2-1", "protein_name": "Host cell factor 2", "gene_name": "Hcfc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAPSLLNWRRVSSFTGPVPRARHGHRAVAIRELMIIFGGGNEGIADELHVYNTVTNQWFLPAVRGDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNELYELQASRWLWKKVKPQPPPSGLPPCPRLGHSFSLYGNKCYLFAGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSVPATKGTVPSPRESHTAVIYCKRDSGSPKMYVFGGMCGARLDDLWQLDLETMSWSKPETKGTVPLPRSLHTASVIGNKMYIFGGWVPHKGENTENSPHDCEWRCTSSFSYLNLDTAEWTTLVSDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSGRDGYKKALNSQVCCKDLWYLDTEKPPAPSQVQLIKATTNSFHVKWDEVPTVEGYLLQLNTDLTHQAASPDASAAPNTLGGRTDPHRQGSNSILHNSVSDPANCTKPEHTAVAARGMSLKSKPDSRAADSSVALHSPLAPNTSNNNSCMADMLWKSEVDEICALPATKISRVEAHAAATPFSKETPSNPVAILKAEQWCDVGIFKNNTALVSQFYLLPKGKQSMSKVGNADVPDYSLLKKQDLVPGTVYKFRVAAINGCGIGPFSKLSEFKTCIPGFPGAPSTVRISKNVEGIHLSWEPPTSPSGNILEYSAYLAIRTAQVQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRPAIVFRISAKNEKGYGPATQVRWLQGNSKKAPLS", "length": 723 }, "evidence": [ { "id": "E1BEJ7", "url": "https://omabrowser.org/oma/group/E1BEJ7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D968-1", "protein_name": "Host cell factor 2", "gene_name": "Hcfc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAPSLLNWRRVSSFTGPVPRARHGHRAVAIRELMIIFGGGNEGIADELHVYNTVTNQWFLPAVRGDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNELYELQASRWLWKKVKPQPPPSGFPPCPRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPATKGVVPSPRESHTAIIYCKKDSASPKMYVFGGMCGARLDDLWQLDLETMSWSKPETKGTVPLPRSLHTASVIGNKMYIFGGWVPHKGENPETSPHDCEWRCTSSFSYLNLDTAEWTTLVSDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSGRDGYKKALNSQVCCKDLWYLDTEKPPAPSQVQLIKATTNSFHVKWDEVPTVEGYLLQLNTDLTYQATSSDSSAAPSVLGGRMDPHRQGSNSTLHNSVSDTVNSTKTEHTAVRGTSLRSKPDSRAVDSSAALHSPLAPNTSNNSSWVTDMLRKNEVDEICALPATKISRVEVHAAATPFSKETPSNPVAILKAEQWCDVGIFKNNTALVSQFYLLPKGKQSMSKVGNADVPDYSLLKKQDLVPGTVYKFRVAAINGCGIGPLSKVSEFKTCTPGFPGAPSTVRISKNVDGIHLSWEPPTSPSGNILEYSAYLAIRTAQMQDNPSQLVFMRIYCGLKTSCTVTAGQLANAHIDYTSRPAIVFRISAKNEKGYGPATQVRWLQDQEKDVGPWF", "length": 722 }, "evidence": [ { "id": "E1BEJ7", "url": "https://omabrowser.org/oma/group/E1BEJ7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y5Z7-1", "protein_name": "Host cell factor 2", "gene_name": "HCFC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAPSLLNWRRVSSFTGPVPRARHGHRAVAIRELMIIFGGGNEGIADELHVYNTATNQWFLPAVRGDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNELYELQASRWLWKKVKPHPPPSGLPPCPRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGVVPSPRESHTAVIYCKKDSGSPKMYVFGGMCGARLDDLWQLDLETMSWSKPETKGTVPLPRSLHTASVIGNKMYIFGGWVPHKGENTETSPHDCEWRCTSSFSYLNLDTTEWTTLVSDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSGRDGYKKALNSQVCCKDLWYLDTEKPPAPSQVQLIKATTNSFHVKWDEVSTVEGYLLQLSTDLPYQAASSDSSAAPNMQGVRMDPHRQGSNNIVPNSINDTINSTKTEQPATKETSMKNKPDFKALTDSNAILYPSLASNASNHNSHVVDMLRKNEGPHTSANVGVLSSCLDVRTVIPETSVSSTVSSTQTMVTQQTIKTESSSTNGAVVKDETSLTTFSTKSEVDETYALPATKISRVETHATATPFSKETPSNPVATVKAGERQWCDVGIFKNNTALVSQFYLLPKGKQSISKVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRISKNVEGIHLSWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRPAIVFRISAKNEKGYGPATQVRWLQGNNKKAPLN", "length": 792 }, "evidence": [ { "id": "E1BEJ7", "url": "https://omabrowser.org/oma/group/E1BEJ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "X1WCP5-1", "protein_name": "Host cell factor 2", "gene_name": "hcfc2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MIKKGPLWKRVRSYAGPVPRARHGHRAVAIRELLVVFGGGNEGIATDLHVYNSVTKQWFLPAVRGDIPPGCAAHGFVCEGTRILVFGGMVEFGQYTNSLYELQASRWLWKKLKPRPPKNGSLPCPRIGHSFTLHANKCYLFGGMANDSEDPNGNIPRYLDDFYELELQAQSGVKGWNVPETKGGGPSARESHSSVVYCGKGGSSPRLYIFGGMCGDRLNDLWQLDIETMTWSLPPTRGQLPLPRSLHTSNVIGNKLYVFGGWVPIGEEEEALAADGVKWICTNSLSMLNFDTLTWHNLTPEEHQQGLVEQDENNADWPRARAGHCAVTVGSRLCIWSGRDGYKKYNNYQVCCKDLWYLETERPATPGAVFLVKSTISMLHVAWRPLLAAECYLLQLQPITSHHSTSAEPQTAPTPPPEPGDRRESVQKDAKSADVKIKREKDYSSQESPLSQKEKGKDGADIQPTERDISPEPSKQPETTKDWFDVGVFKTLFCEVTHYFLPSENGDMASVLSAQYTSSDTEWKLPGPHSFTGCEKQELDSGITYRFRVAGLNSCGLGDFSPISEFKTCQPGFPGAPSAVKITKGTDSVHISWEPPTSVSGKIMEYSMYLAVRKSRGNSLVERPGELAFIRIYRGTKTSCTVTEAQLSNAHIDCSARPAIVFRIAAKNDQGYGPATQIRWLQDASKLKPSVMPTDSSSSAAEPDTTCR", "length": 708 }, "evidence": [ { "id": "E1BEJ7", "url": "https://omabrowser.org/oma/group/E1BEJ7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ7", "url": "https://www.uniprot.org/uniprotkb/E1BEJ7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ7", "url": "https://www.uniprot.org/uniprotkb/E1BEJ7" } ], "pmid": "" }, { "name": "histone methyltransferase complex", "id": "GO:0035097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035097", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ7", "url": "https://www.uniprot.org/uniprotkb/E1BEJ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ7", "url": "https://www.uniprot.org/uniprotkb/E1BEJ7" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ7", "url": "https://www.uniprot.org/uniprotkb/E1BEJ7" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ7", "url": "https://www.uniprot.org/uniprotkb/E1BEJ7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "E1BEJ7", "url": "https://www.uniprot.org/uniprotkb/E1BEJ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 147, "end_pos": 149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 461, "end_pos": 463, "annotation": "n_glycosylation_sequon" }, { "start_pos": 471, "end_pos": 473, "annotation": "n_glycosylation_sequon" }, { "start_pos": 606, "end_pos": 608, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BEJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEJ7" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 583, "end_pos": 675, "start_aa": "Thr", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 147, "end_pos": 149 }, { "start_pos": 461, "end_pos": 463 }, { "start_pos": 471, "end_pos": 473 }, { "start_pos": 606, "end_pos": 608 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": 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"MAAPSAGFQYPLQPKEQMAADRGRRMLRGCGMHPDHQEALKKNRVVLAKELLLSELLEHLLEKDIITLEMREHIQAKTGSFGQNVELLNLLPKRGPQAFDAFCVALRETKQSHLEELLLRTLSGLQPVVPPLSCDYDLSLPFPVCESCTRHKRLHLSPDAVEHSLDHGDGPPCLQVKPCTPEFYQTHHHLAYRLQSRPRGLALVLSNVHFTGEKDLEFRSGGDVDHSTLVTLFKLLGYKVHVLLDQTAQEMQEKLQNFAQLPVHRVTDSCIVALLSHGVEGGVYGVDGKLLQLQEVFRLFDNANCPSLQNKPKMFFIQACRGDETDRGVDLQDGKNHDRSPKCEESDASREELLKMRLPTRSDMICGYACLRGTAAMRNTKRGSWYVEALTQVFSERACDMHVADMLVKVNALIKEREGYAPGTEFHRCKEMSEYCSTLCRHLYLFPGHPPT", "length": 452, "header": "tr|E1BJT6-1|E1BJT6_BOVIN Isoform 1 of Caspase-2 OS=Bos taurus OX=9913 GN=CASP2 PE=3 SV=3 CANONICAL=E1BJT6-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T831-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T831/entry", "sequence": { "sequence": "MAAPSAGFQYPLQPKEQMAADRGRRMLRGCGMHPDHQEALKKNRVVLAKELLLSELLEHLLEKDIITLEMREHIQAKTGSFGQNVELLNLLPKRGPQAFDAFCEALHA", "length": 108, "header": "tr|A0AAA9T831-1|A0AAA9T831_BOVIN Computationally mapped isoform of Caspase 2 OS=Bos taurus OX=9913 GN=CASP2 PE=4 SV=1 CANONICAL=E1BJT6-1" }, "locus": { "chromosome": "4", "start_pos": 106682809, "end_pos": 106677832, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135899.2", "url": "https://www.ensembl.org/id/ENSBTAT00000135899.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092967.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092967.1" } ] } }, { "isoform_ac": "E1BJT6-1", "url": "https://www.uniprot.org/uniprotkb/E1BJT6/entry", "sequence": { "sequence": "MAAPSAGFQYPLQPKEQMAADRGRRMLRGCGMHPDHQEALKKNRVVLAKELLLSELLEHLLEKDIITLEMREHIQAKTGSFGQNVELLNLLPKRGPQAFDAFCVALRETKQSHLEELLLRTLSGLQPVVPPLSCDYDLSLPFPVCESCTRHKRLHLSPDAVEHSLDHGDGPPCLQVKPCTPEFYQTHHHLAYRLQSRPRGLALVLSNVHFTGEKDLEFRSGGDVDHSTLVTLFKLLGYKVHVLLDQTAQEMQEKLQNFAQLPVHRVTDSCIVALLSHGVEGGVYGVDGKLLQLQEVFRLFDNANCPSLQNKPKMFFIQACRGDETDRGVDLQDGKNHDRSPKCEESDASREELLKMRLPTRSDMICGYACLRGTAAMRNTKRGSWYVEALTQVFSERACDMHVADMLVKVNALIKEREGYAPGTEFHRCKEMSEYCSTLCRHLYLFPGHPPT", "length": 452, "header": "tr|E1BJT6-1|E1BJT6_BOVIN Isoform 1 of Caspase-2 OS=Bos taurus OX=9913 GN=CASP2 PE=3 SV=3 CANONICAL=E1BJT6-1" }, "locus": { "chromosome": "4", "start_pos": 106693943, "end_pos": 106677832, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024166.8", "url": "https://www.ensembl.org/id/ENSBTAT00000024166.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024166.7", "url": "https://www.ensembl.org/id/ENSBTAP00000024166.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Relationship between group II caspase activity of bovine preimplantation embryos and capacity for hatching.", "journal": "The Journal of reproduction and development", "date": "2008-06", "authors": "Jousan Frank Dean, de Castro E Paula Luiz Augusto, Brad Amber Marie, Roth Zvi, Hansen Peter James", "evidence": [ { "database": "RefSeq", "id": "NP_001137576", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137576" } ], "reference": [ { "type": "PubMed", "id": "18277054", "url": "https://glygen.org/publication/PubMed/18277054" } ] }, { "title": "Coenzyme Q10 rescues ethanol-induced corneal fibroblast apoptosis through the inhibition of caspase-2 activation.", "journal": "The Journal of biological chemistry", "date": "2013-04-26", "authors": "Chen Chun-Chen, Liou Shiow-Wen, Chen Chi-Chih, Chen Wen-Chung, Hu Fung-Rong, Wang I-Jong, Lin Shing-Jong", "evidence": [ { "database": "RefSeq", "id": "NP_001137576", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137576" } ], "reference": [ { "type": "PubMed", "id": "23430247", "url": "https://glygen.org/publication/PubMed/23430247" } ] } ], "pathway": [ { "id": "bta:531419", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:531419", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "death domain binding", "id": "GO:0070513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070513", "evidence": [ { "database": "UniProtKB", "id": "E1BJT6", "url": "https://www.uniprot.org/uniprotkb/E1BJT6" } ], "pmid": "" }, { "name": "protease binding", "id": "GO:0002020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002020", "evidence": [ { "database": "UniProtKB", "id": "E1BJT6", "url": "https://www.uniprot.org/uniprotkb/E1BJT6" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "E1BJT6", "url": "https://www.uniprot.org/uniprotkb/E1BJT6" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1BJT6", "url": "https://www.uniprot.org/uniprotkb/E1BJT6" } ], "pmid": "" }, { "name": "cysteine-type endopeptidase activity", "id": "GO:0004197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004197", "evidence": [ { "database": "UniProtKB", "id": "E1BJT6", "url": "https://www.uniprot.org/uniprotkb/E1BJT6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "E1BJT6", "url": "https://www.uniprot.org/uniprotkb/E1BJT6" } ], "pmid": "" }, { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "E1BJT6", "url": "https://www.uniprot.org/uniprotkb/E1BJT6" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "E1BJT6", "url": "https://www.uniprot.org/uniprotkb/E1BJT6" } ], "pmid": "" }, { "name": "cellular response to mechanical stimulus", "id": "GO:0071260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071260", "evidence": [ { "database": "UniProtKB", "id": "E1BJT6", "url": "https://www.uniprot.org/uniprotkb/E1BJT6" } ], "pmid": "" }, { "name": "DNA damage response, signal transduction by p53 class mediator", "id": "GO:0030330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030330", "evidence": [ { "database": "UniProtKB", "id": "E1BJT6", "url": "https://www.uniprot.org/uniprotkb/E1BJT6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BJT6", "url": "https://www.uniprot.org/uniprotkb/E1BJT6" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "E1BJT6", "url": "https://www.uniprot.org/uniprotkb/E1BJT6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BJT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJT6" }, { "id": "PS50209", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50209" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CARD", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 121, "start_aa": "Met", "end_aa": "Thr", "glycosite_overlap": [] }, { "evidence": [ { "id": "E1BJT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJT6" }, { "id": "PS50207", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50207" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Caspase family p10", "eco_id": "ECO_0000259", "start_pos": 354, "end_pos": 447, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "E1BJT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJT6" }, { "id": "PS50208", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50208" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Caspase family p20", "eco_id": "ECO_0000259", "start_pos": 198, "end_pos": 324, "start_aa": "Pro", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.22.55", "ec_name": "Strict requirement for an Asp residue at P1, with 316-Asp being essential for proteolytic activity and has a preferred cleavage sequence of Val-Asp-Val-Ala-Asp-|-.", "evidence": [ { "id": "3.4.22.55", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.22.55" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1MCN2-1", "uniprot_ac": "F1MCN2", "uniprot_id": "F1MCN2_BOVIN", "mass": { "chemical_mass": 78157.0, "monoisotopic_mass": 78157.0 }, "refseq": {}, "gene_names": [ { "name": "SP3", "type": "recommended", "evidence": [ { "id": "F1MCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MCN2" } ] } ], "protein_names": [ { "name": "Sp3 transcription factor", "type": "synonym", "evidence": [ { "id": "F1MCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MCN2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1MCN2", "url": "https://www.uniprot.org/uniprotkb/F1MCN2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SP3", "url": "https://www.uniprot.org/uniprotkb/F1MCN2", "locus": { "chromosome": "2", "start_pos": 22854606, "end_pos": 22797247, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000176", "url": "https://www.ensembl.org/id/ENSBTAG00000000176" } ] } } ], "crossref": [ { "id": "F1MCN2", "url": "https://alphafold.ebi.ac.uk/entry/F1MCN2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000176", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000176", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22537", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22537", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "540766", "url": "https://www.ncbi.nlm.nih.gov/gene/540766", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540766", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540766", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-3232118", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3232118", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LST8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LST8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LST8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LST8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MCN2", "url": "https://www.uniprot.org/uniprotkb/F1MCN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MCN2-1", "url": "https://www.uniprot.org/uniprotkb/F1MCN2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTAPEKPVKQEEMAALDVDSGGGGGGHGEYLQQQQQHGNGAVAAAAAAAQTGDLASAQLGGAPNRWEVLSATPTTIKDEAGNLVQIPSAATSSGQYVLPLQNLQNQQIFSVAPGSDSSNGTVSNVQYQVIPQIQSSDGQQVQIGFTGSSDNGGINQESGQIQIIPGSNQTLLASGTPPANIQNLIPQTGQVQVQGVAIGGSSFPGQTQVVANVPLGLPGNITFVPINSVDLDSLGLSGSSQTMTAGINADGHLINTGQAMDSSDNSERTGERVSPDINETNTDTDLFVPTSSSSQLPVTIDSTGILQQNTNSLTTTSGQVHSSDLQGNYIQSPVSEETQAQNIQVSTAQPVVQHLQLQESQQPTSQAQIVQGITPQTIHGVQASGQNITQQALQNLQLQLNPGTFLIQAQTVTPSGQITWQTFQVQGVQNLQNLQIQNTAAQQITLTPVQTLTLGQVAAGGALSSTPVSLSTGQLPNLQTVTVNSIDSTGIQLHPGENADSPADIRIKEEEPDPEEWQLSGDSTLNTNDLTHLRVQVVDEEGDQQHQEGKRLRRVACTCPNCKEGGGRGTNLGKKKQHICHIPGCGKVYGKTSHLRAHLRWHSGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKKFVCPECSKRFMRSDHLAKHIKTHQNKKGIHSSSTVLASVEAARDDTLITAGGTTLILANIQQGSVSGIGTVNTSTTSNQDILTNTEIPLQLVTVSGNETME", "length": 738, "header": "tr|F1MCN2-1|F1MCN2_BOVIN Isoform 1 of Sp3 transcription factor OS=Bos taurus OX=9913 GN=SP3 PE=3 SV=3 CANONICAL=F1MCN2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LST8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LST8/entry", "sequence": { "sequence": "MTAPEKPVKQEEMAALDVDSGGGGGGHGEYLQQQQQHGNGAVAAAAAAAQDTQPSPLALLAATCSKIGPPSPGDDEEEAAAAAGAPAAAAAGATGDLASAQLGGAPNRWEVLSATPTTIKDEAGNLVQIPSAATSSGQYVLPLQNLQNQQIFSVAPGSDSSNGTVSNVQYQVIPQIQSSDGQQVQIGFTGSSDNGGINQESGQIQIIPGSNQTLLASGTPPANIQNLIPQTGQVQVQGVAIGGSSFPGQTQVVANVPLGLPGNITFVPINSVDLDSLGLSGSSQTMTAGINADGHLINTGQAMDSSDNSERTGERVSPDINETNTDTDLFVPTSSSSQLPVTIDSTGILQQNTNSLTTTSGQVHSSDLQGNYIQSPVSEETQAQNIQVSTAQPVVQHLQLQESQQPTSQAQIVQGITPQTIHGVQASGQNITQQALQNLQLQLNPGTFLIQAQTVTPSGQITWQTFQVQGVQNLQNLQIQNTAAQQITLTPVQTLTLGQVAAGGALSSTPVSLSTGQLPNLQTVTVNSIDSTGIQLHPGENADSPADIRIKEEEPDPEEWQLSGDSTLNTNDLTHLRVQVVDEEGDQQHQEGKRLRRVACTCPNCKEGGGRGTNLGKKKQHICHIPGCGKVYGKTSHLRAHLRWHSGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKKFVCPECSKRFMRSDHLAKHIKTHQNKKGIHSSSTVLASVEAARDDTLITAGGTTLILANIQQGSVSGIGTVNTSTTSNQDILTNTEIPLQLVTVSGNETME", "length": 781, "header": "tr|A0A3Q1LST8-1|F1MCN2_BOVIN Computationally mapped isoform of Sp3 transcription factor OS=Bos taurus OX=9913 GN=SP3 PE=3 SV=2 CANONICAL=F1MCN2-1" }, "locus": { "chromosome": "2", "start_pos": 22853602, "end_pos": 22797446, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082926.3", "url": "https://www.ensembl.org/id/ENSBTAT00000082926.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060342.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060342.2" } ] } }, { "isoform_ac": "F1MCN2-1", "url": "https://www.uniprot.org/uniprotkb/F1MCN2/entry", "sequence": { "sequence": "MTAPEKPVKQEEMAALDVDSGGGGGGHGEYLQQQQQHGNGAVAAAAAAAQTGDLASAQLGGAPNRWEVLSATPTTIKDEAGNLVQIPSAATSSGQYVLPLQNLQNQQIFSVAPGSDSSNGTVSNVQYQVIPQIQSSDGQQVQIGFTGSSDNGGINQESGQIQIIPGSNQTLLASGTPPANIQNLIPQTGQVQVQGVAIGGSSFPGQTQVVANVPLGLPGNITFVPINSVDLDSLGLSGSSQTMTAGINADGHLINTGQAMDSSDNSERTGERVSPDINETNTDTDLFVPTSSSSQLPVTIDSTGILQQNTNSLTTTSGQVHSSDLQGNYIQSPVSEETQAQNIQVSTAQPVVQHLQLQESQQPTSQAQIVQGITPQTIHGVQASGQNITQQALQNLQLQLNPGTFLIQAQTVTPSGQITWQTFQVQGVQNLQNLQIQNTAAQQITLTPVQTLTLGQVAAGGALSSTPVSLSTGQLPNLQTVTVNSIDSTGIQLHPGENADSPADIRIKEEEPDPEEWQLSGDSTLNTNDLTHLRVQVVDEEGDQQHQEGKRLRRVACTCPNCKEGGGRGTNLGKKKQHICHIPGCGKVYGKTSHLRAHLRWHSGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKKFVCPECSKRFMRSDHLAKHIKTHQNKKGIHSSSTVLASVEAARDDTLITAGGTTLILANIQQGSVSGIGTVNTSTTSNQDILTNTEIPLQLVTVSGNETME", "length": 738, "header": "tr|F1MCN2-1|F1MCN2_BOVIN Isoform 1 of Sp3 transcription factor OS=Bos taurus OX=9913 GN=SP3 PE=3 SV=3 CANONICAL=F1MCN2-1" }, "locus": { "chromosome": "2", "start_pos": 22853602, "end_pos": 22797446, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000201.7", "url": "https://www.ensembl.org/id/ENSBTAT00000000201.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000201.6", "url": "https://www.ensembl.org/id/ENSBTAP00000000201.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 413, "start_aa": "Thr", "end_pos": 413, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr413", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:540766", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540766", "resource": "KEGG Pathway" }, { "id": "R-BTA-3232118", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3232118", "resource": "Reactome", "description": "SUMOylation of transcription factors" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "F1MCN2", "url": "https://www.uniprot.org/uniprotkb/F1MCN2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1MCN2", "url": "https://www.uniprot.org/uniprotkb/F1MCN2" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "F1MCN2", "url": "https://www.uniprot.org/uniprotkb/F1MCN2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1MCN2", "url": "https://www.uniprot.org/uniprotkb/F1MCN2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1MCN2", "url": "https://www.uniprot.org/uniprotkb/F1MCN2" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "F1MCN2", "url": "https://www.uniprot.org/uniprotkb/F1MCN2" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1MCN2", "url": "https://www.uniprot.org/uniprotkb/F1MCN2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1MCN2", "url": "https://www.uniprot.org/uniprotkb/F1MCN2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1MCN2", "url": "https://www.uniprot.org/uniprotkb/F1MCN2" } ], "pmid": "" }, { "name": "transcription repressor complex", "id": "GO:0017053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017053", "evidence": [ { "database": "UniProtKB", "id": "F1MCN2", "url": "https://www.uniprot.org/uniprotkb/F1MCN2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1MCN2", "url": "https://www.uniprot.org/uniprotkb/F1MCN2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1MCN2", "url": "https://www.uniprot.org/uniprotkb/F1MCN2" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "F1MCN2", "url": "https://www.uniprot.org/uniprotkb/F1MCN2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 387, "end_pos": 389, "annotation": "n_glycosylation_sequon" }, { "start_pos": 709, "end_pos": 711, "annotation": "n_glycosylation_sequon" }, { "start_pos": 734, "end_pos": 736, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1MCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MCN2" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 578, "end_pos": 607, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 413 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 119, "end_pos": 121 }, { "start_pos": 168, "end_pos": 170 }, { "start_pos": 220, "end_pos": 222 }, { "start_pos": 278, "end_pos": 280 }, { "start_pos": 387, "end_pos": 389 }, { "start_pos": 709, "end_pos": 711 }, { "start_pos": 734, "end_pos": 736 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 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"crossref": [ { "id": "ENSBTAG00000020281", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020281", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "510366", "url": "https://www.ncbi.nlm.nih.gov/gene/510366", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:510366", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:510366", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1NL90", "url": "https://www.orthodb.org/?gene=A0A3Q1NL90", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BMB1", "url": "https://www.orthodb.org/?gene=E1BMB1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BQ19", "url": "https://www.orthodb.org/?gene=E1BQ19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MYK5", "url": "https://www.orthodb.org/?gene=G3MYK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18905", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18905", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18905:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18905:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27974", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27974", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059746815", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059746815", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MD39", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MD39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MD39-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MD39-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NL90", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NL90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NL90-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NL90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RV22", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RV22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RV22-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RV22-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S6S4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6S4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S6S4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6S4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMB1", "url": "https://www.uniprot.org/uniprotkb/E1BMB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMB1-1", "url": "https://www.uniprot.org/uniprotkb/E1BMB1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQ19", "url": "https://www.uniprot.org/uniprotkb/E1BQ19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQ19-1", "url": "https://www.uniprot.org/uniprotkb/E1BQ19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYK5", "url": "https://www.uniprot.org/uniprotkb/G3MYK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYK5-1", "url": "https://www.uniprot.org/uniprotkb/G3MYK5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDEAEQDQHEARLKELFDSFDTTGTGSLGQEELTDLCHMLSLEEVAPVLQETLLQDNLLGRVHFDQFKEALILILSRTLSNEEHFQEPDCTLEAQPKYVRGGKRYGRRSLPEFQESVEEFAEVTVIEPLGEEAQPSHIPASERSEHWKTQRSEEYEAEGQLRFWNPDDLKASQTGSLAPQDWIEEKLQEVCEDLGITRDGHLNRKKLVSICEQYGLQNVDGEMLEEVFHNLDPDGMMSVEDFFYGLFKNGKPLTPSASTPYRQLKRHISMQSFDESGRRTTAPSAMMSTIGFRVFSCLDDGMGYASVERILDTWQEEGIENSQEILKALDFSLDGNVNLTELTLALENELLVTKNSIHQAALASFKAEIRHLLERVDQMLREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYKERIAALKNEFRKEREQILQQVGKQRLELEQEIEKAKTEENYVRDRLALSLKENSRLENELLENAEKLAEYESLTNKLQRNLENVLAEKFGDLDPSSAEFFLQEERLTQMRNEYEQQCRLLQDQVDELQSELQEYRTQGKVSRLPLQNSLSEELDINSGCIEPDQGLGSEECNPLNMSIEAELVIEQMKEQHHRELCHLRLELEDKVNYYEKQLDETKVAFEKEQENMKLKCENEVHILEEQISDLKNKIAELQGQTEVLKEAQHVAICRHEEEKKQLQMKWDEEKAHVQEELRLEHEMALRARLEQVEESFNRERERLVQNGAWTEEKVRGLTQKLEQVHQEQLKSLVEKHILEKEELQKELLEKHQRELHEGREKMETECNRRTSQIEAQFQADCQKVTERYEHALRSLEVHYRHQLKELLDQQCEERSQWEFEKDELTQECAEAQEQLKETLQREKATSLVLTQEREMLEKTYKEHLNSMVVEREQLLQDLEDLRKVSESQQSLLSNQILELKSSHERELKDREQILCQAGTSEQLVSQRLEQLQREHDQERQEMMSKLLVMESVHRATCEKADRERAEMSTEISRLQNKIKEMEQVVSPPSRLQNSCQVIGGEEAEENGAMSLLQQGEQLLEENGDVLLSLQRAHERAVKENVKMATEISRLQQRLQKLEPESVMSSCLDEPATGLFGNSVEQTEPFLQPNRIKQAEGGTTQRILSDLQGDEVRDLESTGTSSGQRQVRVEESEASIESFSELENSEETRTETWDLKNQVGQLREQLMILRADCDRASEKKQDLLFDVSVLKKKLKMLERIPEASPKYKVLYEDASRENECLQEELRMMETRYDEALESNKELTSEMFRLQDELKKVEEMTDTFLSLEKSYKEIKRENEELHVLVLRLQGKIEKLRERAVLQCDCFSLWEAHLDNLEVGPDEKVFELNQTLDERVPNVMSVHHIIEEHLYQENQYLEQENTQLLEKVKAHEIAWLHGTLQTHRDKLGAQNQVVLEENTALLGLQDKHFQHQATIAELEREKKKLQELTRKLRERVTALVKQKDVPSQGEKEEELKAMMHDLQITCSEMQQKVELLRYESEKLQEENSILRNEITTLNEEDSISNLKLGKLSGSQEEMWQKIETVKQEKAAVQKMVENLKKQISELKTKNQQLDLENMKLSQKNSQNQKELQELNQRLAEMLSQKDKEPGHSACEEWEQEKSNLKEELEHCKLQSSTLVSSLEAELSEVKIQTHIVEQENLLLKDELEKVKQLCRCPDLSDFQQKISSILSHNEKLLKEKEALSEELNICVDKLAKSSLLEHRIATMKQEQKSWEHQSESLKSQLVASQEKVQNLEDTLQNVNLQMSRIKSDLRVTQQEKEALKQEVMSLHKQLQNASDKNWAPEIGIHPSGFHNQQQRLSWDKLDHLINEEQQLLWQENERVQTMVQNTKPELIHSREKVRQLESNLPSPKHQKHLNSSGTVKPTEQEKLSLKRECEQFQKERSPTNRKVSQMKSLERELETIHLENEGLKKKQVKLDEQLMEMQHLRSTVMLSPSPHAWELQLLQQQTCPVVPREQFLQLQRQLLQAERINQCLQEELENRTSETNTPQGNQEYLVTVMEERMLEVEQKLKLVKRLLQEKVNQLKEQLCKNTKADAIVKDLYVENAQLLKALEMTEQRQKTAEKKNYLLEEKIASLSNIVRNLTPAPLTSTPPLRS", "length": 2137, "header": "tr|E1BMB1-1|E1BMB1_BOVIN Isoform 1 of Ninein OS=Bos taurus OX=9913 GN=NIN PE=4 SV=3 CANONICAL=E1BMB1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MD39-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MD39/entry", "sequence": { "sequence": "MDEAEQDQHEARLKELFDSFDTTGTGSLGQEELTDLCHMLSLEEVAPVLQETLLQDNLLGRVHFDQFKEALILILSRTLSNEEHFQEPDCTLEAQPKYVRGGKRYGRRSLPEFQESVEEFAEVTVIEPLGEEAQPSHIPASERSEHWKTQRSEEYEAEGQLRFWNPDDLKASQTGSLAPQDWIEEKLQEVCEDLGITRDGHLNRKKLVSICEQYGLQNVDGEMLEEVFHNLDPDGMMSVEDFFYGLFKNGKPLTPSASTPYRQLKRHISMQSFDESGRRTTAPSAMMSTIGFRVFSCLDDGMGYASVERILDTWQEEGIENSQEILKALDFSLDGNVNLTELTLALENELLVTKNSIHQAALASFKAEIRHLLERVDQMLREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYKERIAALKNEFRKEREQILQQVGKQRLELEQEIEKAKTEENYVRDRLALSLKENSRLENELLENAEKLAEYESLTNKLQRNLENVLAEKFGDLDPSSAEFFLQEERLTQMRNEYEQQCRLLQDQVDELQSELQEYRTQGKVSRLPLQNSLSEELDINSGCIEPDQGLGSEECNPLNMSIEAELVIEQMKEQHHRELCHLRLELEDKVNYYEKQLDETKVAFEKEQENMKLKCENEVHILEEQISDLKNKIAELQGQTEVLKEAQHVAICRHEEEKKQLQMKWDEEKAHVQEELRLEHEMALRARLEQVEESFNRERERLVQNGAWTEEKVRGLTQKLEQVHQEQLKSLVEKHILEKEELQKELLEKHQRELHEGREKMETECNRRTSQIEAQFQADCQKVTERYEHALRSLEVHYRHQLKELLDQQCEERSQWEFEKDELTQECAEAQEQLKETLQREKATSLVLTQEREMLEKTYKEHLNSMVVEREQLLQDLEDLRKVSESQQSLLSNQILELKSSHERELKDREQILCQAGTSEQLVSQRLEQLQREHDQERQEMMSKLLVMESVHRATCEKADRERAEMSTEISRLQNKIKEMEQVVSPPSRLQNSCQVIGGEEAEENGAMSLLQQGEQLLEENGDVLLSLQRAHERAVKENVKMATEISRLQQRLQKLEPESVMSSCLDEPATGLFGNSVEQTEPFLQPNRIKQAEGGTTQRILSDLQGDEVRDLESTGTSSGQRQVRVEESEASIESFSELENSEETRTETWDLKNQVGQLREQLMILRADCDRASEKKQDLLFDVSVLKKKLKMLERIPEASPKYKVLYEDASRENECLQEELRMMETRYDEALESNKELTSEMFRLQDELKKVEEMTDTFLSLEKSYKEIKRENEELHVLVLRLQGKIEKLRERAVLQCDCFSLWEAHLDNLEVGPDEKVFELNQTLDERVPNVMSVHHIIEEHLYQENQYLEQENTQLLEKVKAHEIAWLHGTLQTHRDKLGAQNQVVLEENTALLGLQDKHFQHQATIAELEREKKKLQELTRKLRERVTALVKQKDVPSQGEKEEELKAMMHDLQITCSEMQQKVELLRYESEKLQEENSILRNEITTLNEEDSISNLKLGKLSGSQEEMWQKIETVKQEKAAVQKMVENLKKQISELKTKNQQLDLENMKLSQKNSQNQKELQELNQRLAEMLSQKDKEPGHSACEEWEQEKSNLKEELEHCKLQSSTLVSSLEAELSEVKIQTHIVEQENLLLKDELEKVKQLCRCPDLSDFQQKISSILSHNEKLLKEKEALSEELNICVDKLAKSSLLEHRIATMKQEQKSWEHQSESLKSQLVASQEKVQNLEDTLQNVNLQMSRIKSDLRVTQQEKEALKQEVMSLHKQLQNASDKNWAPEIGIHPSGFHNQQQRLSWDKLDHLINEEQQLLWQENERVQTMVQNTKPELIHSREKVRQLESNLPSPKHQKHLNSSGTVKPTEQEKLSLKRECEQFQKERSPTNRKVSQMKSLERELETIHLENEGLKKKQVKLDEQLMEMQHLRSTVMLSPSPHAWELQLLQQQTCPVVPREQFLQLQRQLLQAERINQCLQEELENRTSETNTPQALLPEQRAVHADSYRRIGHL", "length": 2050, "header": "tr|A0A3Q1MD39-1|A0A3Q1MD39_BOVIN Computationally mapped isoform of Ninein OS=Bos taurus OX=9913 GN=NIN PE=4 SV=1 CANONICAL=E1BMB1-1" }, "locus": { "chromosome": "10", "start_pos": 43690547, "end_pos": 43600100, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079287.2", "url": "https://www.ensembl.org/id/ENSBTAT00000079287.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068305.2", "url": "https://www.ensembl.org/id/ENSBTAP00000068305.2" } ] } }, { "isoform_ac": "A0A3Q1NL90-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NL90/entry", "sequence": { "sequence": "MDEAEQDQHEARLKELFDSFDTTGTGSLGQEELTDLCHMLSLEEVAPVLQETLLQDNLLGRVHFDQFKEALILILSRTLSNEEHFQEPDCTLEAQPKYVRGGKRYGRRSLPEFQESVEEFAEVTVIEPLGEEAQPSHIPASERSEHWKTQRSEEYEAEGQLRFWNPDDLKASQTGSLAPQDWIEEKLQEVCEDLGITRDGHLNRKKLVSICEQYGLQNVDGEMLEEVFHNLDPDGMMSVEDFFYGLFKNGKPLTPSASTPYRQLKRHISMQSFDESGRRTTAPSAMMSTIGFRVFSCLDDGMGYASVERILDTWQEEGIENSQEILKALDFSLDGNVNLTELTLALENELLVTKNSIHQAALASFKAEIRHLLERVDQMLREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYKERIAALKNEFRKEREQILQQVGKQRLELEQEIEKAKTEENYVRDRLALSLKENSRLENELLENAEKLAEYESLTNKLQRNLENVLAEKFGDLDPSSAEFFLQEERLTQMRNEYEQQCRLLQDQVDELQSELQEYRTQGKVSRLPLQNSLSEELDINSGCIEPDQGLGSEECNPLNMSIEAELVIEQMKEQHHRELCHLRLELEDKVNYYEKQLDETKVAFEKEQENMKLKCENEVHILEEQISDLKNKIAELQGQTEVLKEAQHVAICRHEEEKKQLQMKWDEEKAHVQEELRLEHEMALRARLEQVEESFNRERERLVQNGAWTEEKVRGLTQKLEQVHQEQLKSLVEKHILEKEELQKELLEKHQRELHEGREKMETECNRRTSQIEAQFQADCQKVTERYEHALRSLEVHYRHQLKELLDQQCEERSQWEFEKDELTQECAEAQEQLKETLQREKATSLVLTQEREMLEKTYKEHLNSMVVEREQLLQDLEDLRKVSESQQSLLSNQILELKSSHERELKDREQILCQAGTSEQLVSQRLEQLQREHDQERQEMMSKLLVMESVHRATCEKADRERAEMSTEISRLQNKIKEMEQVVSPPSRLQNSCQVIGGEEAEENGAMSLLQQGEQLLEENGDVLLSLQRAHERAVKENVKMATEISRLQQRLQKLEPESVMSSCLDEPATGLFGNSVEQTEPFLQPNRIKQAEGGTTQRILSDLQGDEVRDLESTGTSSGQRQVRVEESEASIESFSELENSEETRTETWDLKNQVGQLREQLMILRADCDRASEKKQDLLFDVSVLKKKLKMLERIPEASPKYKVLYEDASRENECLQEELRMMETRYDEALESNKELTSEMFRLQDELKKVEEMTDTFLSLEKSYKEIKRENEELHVLVLRLQGKIEKLRERAVLQCDCFSLWEAHLDNLEVGPDEKVFELNQTLDERVPNVMSVHHIIEEHLYQENQYLEQENTQLLEKVKAHEIAWLHGTLQTHRDKLGAQNQVVLEENTALLGLQDKHFQHQATIAELEREKKKLQELTRKLRERVTALVKQKDVPSQGEKEEELKAMMHDLQITCSEMQQKVELLRYESEKLQEENSILRNEITTLNEEDSISNLKLGKLSGSQEEMWQKIETVKQEKAAVQKMVENLKKQISELKTKNQQLDLENMKLSQKNSQNQKELQELNQRLAEMLSQKDKEPGHSACEEWEQEKSNLKEELEHCKLQSSTLVSSLEAELSEVKIQTHIVEQENLLLKDELEKVKQLCRCPDLSDFQQKISSILSHNEKLLKEKEALSEELNICVDKLAKSSLLEHRIATMKQEQKSWEHQSESLKSQLVASQEKVQNLEDTLQNVNLQMSRIKSDLRVTQQEKEALKQEVMSLHKQLQNASDKNWAPEIGIHPSGFHNQQQRLSWDKLDHLINEEQQLLWQENERVQTMVQNTKPELIHSREKVRQLESNLPSPKHQKHLNSSGTVKPTEQEKLSLKRECEQFQKERSPTNRKAHLGDIPGSVPDNHSKVSQMKSLERELETIHLENEGLKKKQVKLDEQLMEMQHLRSTVMLSPSPHAWELQLLQQQTCPVVPREQFLQLQRQLLQAERINQCLQEELENRTSETNTPQGNQEYLVTVMEERMLEVEQKLKLVKRLLQEKVNQLKEQVSFPGHICPPISPSALTPVLNSFIVTNLLTFIV", "length": 2117, "header": "tr|A0A3Q1NL90-1|E1BMB1_BOVIN Computationally mapped isoform of Ninein OS=Bos taurus OX=9913 GN=NIN PE=4 SV=3 CANONICAL=E1BMB1-1" }, "locus": { "chromosome": "10", "start_pos": 43690547, "end_pos": 43598074, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068471.3", "url": "https://www.ensembl.org/id/ENSBTAT00000068471.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073166.3", "url": "https://www.ensembl.org/id/ENSBTAP00000073166.3" } ] } }, { "isoform_ac": "A0AAA9RV22-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RV22/entry", "sequence": { "sequence": "MDEAEQDQHEARLKELFDSFDTTGTGSLGQEELTDLCHMLSLEEVAPVLQETLLQDNLLGRVHFDQFKEALILILSRTLSNEEHFQEPDCTLEAQPKYVRGGKRYGRRSLPEFQESVEEFAEVTVIEPLGEEAQPSHIPASERSEHWKTQRSEEYEAEGQLRFWNPDDLKASQTGSLAPQDWIEEKLQEVCEDLGITRDGHLNRKKLVSICEQYGLQNVDGEMLEEVFHNLDPDGMMSVEDFFYGLFKNGKPLTPSASTPYRQLKRHISMQSFDESGRRTTAPSAMMSTIGFRVFSCLDDGMGYASVERILDTWQEEGIENSQEILKALDFSLDGNVNLTELTLALENELLVTKNSIHQAALASFKAEIRHLLERVDQMLREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYKERIAALKNEFRKEREQILQQVGKQRLELEQEIEKAKTEENYVRDRLALSLKENSRLENELLENAEKLAEYESLTNKLQRNLENVLAEKFGDLDPSSAEFFLQEERLTQMRNEYEQQCRLLQDQVDELQSELQEYRTQGKVSRLPLQNSLSEELDINSGCIEPDQGLGSEECNPLNMSIEAELVIEQMKEQHHRELCHLRLELEDKVNYYEKQLDETKVAFEKEQENMKLKCENEVHILEEQISDLKNKIAELQGQTEVLKEAQHVAICRHEEEKKQLQMKWDEEKAHVQEELRLEHEMALRARLEQVEESFNRERERLVQNGAWTEEKVRGLTQKLEQVHQEQLKSLVEKHILEKEELQKELLEKHQRELHEGRYESEKLQEENSILRNEITTLNEEDSISNLKLGKLSGSQEEMWQKIETVKQEKAAVQKMVENLKKQISELKTKNQQLDLENMKLSQKNSQNQKELQELNQRLAEMLSQKDKEPGHSACEEWEQEKSNLKEELEHCKLQLCRCPDLSDFQQKISSILSHNEKLLKEKEALSEELNICVDKLAKSSLLEHRIATMKQEQKSWEHQSESLKSQLVASQEKVQNLEDTLQNVNLQMSRIKSDLRVTQQEKEALKQEVMSLHKQLQNASDKNWAPEIGIHPSGFHNQQQRLSWDKLDHLINEEQQLLWQENERVQTMVQNTKPELIHSREKVRQLESNLPSPKHQKHLNSSGTVKPTEQEKLSLKRECEQFQKERSPTNRKVSQMKSLERELETIHLENEGLKKKQVKLDEQLMENSVVGTSREGCSSLPEIVCEDAAPEVHCDA", "length": 1240, "header": "tr|A0AAA9RV22-1|A0AAA9RV22_BOVIN Computationally mapped isoform of Ninein OS=Bos taurus OX=9913 GN=NIN PE=4 SV=1 CANONICAL=E1BMB1-1" }, "locus": { "chromosome": "10", "start_pos": 43690547, "end_pos": 43601935, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129133.1", "url": "https://www.ensembl.org/id/ENSBTAT00000129133.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074828.1", "url": "https://www.ensembl.org/id/ENSBTAP00000074828.1" } ] } }, { "isoform_ac": "A0AAA9S6S4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6S4/entry", "sequence": { "sequence": "MDEAEQDQHEARLKELFDSFDTTGTGSLGQEELTDLCHMLSLEEVAPVLQETLLQDNLLGRVHFDQFKEALILILSRTLSNEEHFQEPDCTLEAQPKYVRGGKRYGRRSLPEFQESVEEFAEVTVIEPLGEEAQPSHIPASERSEHWKTQRSEEYEAEGQLRFWNPDDLKASQTGSLAPQDWIEEKLQEVCEDLGITRDGHLNRKKLVSICEQYGLQNVDGEMLEEVFHNLDPDGMMSVEDFFYGLFKNGKPLTPSASTPYRQLKRHISMQSFDESGRRTTAPSAMMSTIGFRVFSCLDDGMGYASVERILDTWQEEGIENSQEILKALDFSLDGNVNLTELTLALENELLVTKNSIHQAALASFKAEIRHLLERVDQMLREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYKERIAALKNEFRKEREQILQQVGKQRLELEQEIEKAKTEENYVRDRLALSLKENSRLENELLENAEKLAEYESLTNKLQRNLENVLAEKFGDLDPSSAEFFLQEERLTQMRNEYEQQCRLLQDQVDELQSELQEYRTQGKVSRLPLQNSLSEELDINSGCIEPDQGLGSEECNPLNMSIEAELVIEQMKEQHHRELCHLRLELEDKVNYYEKQLDETKVAFEKEQENMKLKCENEVHILEEQISDLKNKIAELQGQTEVLKEAQHVAICRHEEEKKQLQMKWDEEKAHVQEELRLEHEMALRARLEQVEESFNRERERLVQNGAWTEEKVRGLTQKLEQVHQEQLKSLVEKHILEKEELQKELLEKHQRELHEGRYESEKLQEENSILRNEITTLNEEDSISNLKLGKLSGSQEEMWQKIETVKQEKAAVQKMVENLKKQISELKTKNQQLDLENMKLSQKNSQNQKELQELNQRLAEMLSQKDKEPGHSACEEWEQEKSNLKEELEHCKLQSSTLVSSLEAELSEVKIQTHIVEQENLLLKDELEKVKQLAKSSLLEHRIATMKQEQKSWEHQSESLKSQLVASQEKVQNLEDTLQNVNLQMSRIKSDLRVTQQEKEALKQEVMSLHKQLQNASDKNWAPEIGIHPSGFHNQQQRLSWDKLDHLINEEQQLLWQENERVQTMVQNTKPELIHSREKVRQLESNLPSPKHQKHLNSSGTVKPTEQEKLSLKRECEQFQKERSPTNRKVSQMKSLERELETIHLENEGLKKKQVKLDEQLMENSVVGTSREGCSSLPEIVCEDAAPEVHCDA", "length": 1237, "header": "tr|A0AAA9S6S4-1|A0AAA9S6S4_BOVIN Computationally mapped isoform of Ninein OS=Bos taurus OX=9913 GN=NIN PE=4 SV=1 CANONICAL=E1BMB1-1" }, "locus": { "chromosome": "10", "start_pos": 43690547, "end_pos": 43601935, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089354.1", "url": "https://www.ensembl.org/id/ENSBTAT00000089354.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078991.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078991.1" } ] } }, { "isoform_ac": "E1BMB1-1", "url": "https://www.uniprot.org/uniprotkb/E1BMB1/entry", "sequence": { "sequence": 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"length": 2137, "header": "tr|E1BMB1-1|E1BMB1_BOVIN Isoform 1 of Ninein OS=Bos taurus OX=9913 GN=NIN PE=4 SV=3 CANONICAL=E1BMB1-1" }, "locus": { "chromosome": "10", "start_pos": 43690547, "end_pos": 43595832, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061216.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061216.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053270.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053270.3" } ] } }, { "isoform_ac": "E1BQ19-1", "url": "https://www.uniprot.org/uniprotkb/E1BQ19/entry", "sequence": { "sequence": "MDEAEQDQHEARLKELFDSFDTTGTGSLGQEELTDLCHMLSLEEVAPVLQETLLQDNLLGRVHFDQFKEALILILSRTLSNEEHFQEPASVGVSCQQAARVSGPLLNAHKLTHSLLIKDCTLEAQPKYVRGGKRYGRRSLPEFQESVEEFAEVTVIEPLGEEAQPSHIPASERSEHWKTQRSEEYEAEGQLRFWNPDDLKASQTGSLAPQDWIEEKLQEVCEDLGITRDGHLNRKKLVSICEQYGLQNVDGEMLEEVFHNLDPDGMMSVEDFFYGLFKNGKPLTPSASTPYRQLKRHISMQSFDESGRRTTAPSAMMSTIGFRVFSCLDDGMGYASVERILDTWQEEGIENSQEILKALDFSLDGNVNLTELTLALENELLVTKNSIHQAALASFKAEIRHLLERVDQMLREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYKERIAALKNEFRKEREQILQQVGKQRLELEQEIEKAKTEENYVRDRLALSLKENSRLENELLENAEKLAEYESLTNKLQRNLENVLAEKFGDLDPSSAEFFLQEERLTQMRNEYEQQCRLLQDQVDELQSELQEYRTQGKVSRLPLQNSLSEELDINSGCIEPDQGLGSEECNPLNMSIEAELVIEQMKEQHHRELCHLRLELEDKVNYYEKQLDETKVAFEKEQENMKLKCENEVHILEEQISDLKNKIAELQGQTEVLKEAQHVAICRHEEEKKQLQMKWDEEKAHVQEELRLEHEMALRARLEQVEESFNRERERLVQNGAWTEEKVRGLTQKLEQVHQEQLKSLVEKHILEKEELQKELLEKHQRELHEGREKMETECNRRTSQIEAQFQADCQKVTERYEHALRSLEVHYRHQLKELLDQQCEERSQWEFEKDELTQECAEAQEQLKETLQREKATSLVLTQEREMLEKTYKEHLNSMVVEREQLLQDLEDLRKVSESQQSLLSNQILELKSSHERELKDREQILCQAGTSEQLVSQRLEQLQREHDQERQEMMSKLLVMESVHRATCEKADRERAEMSTEISRLQNKIKEMEQVVSPPSRLQNSCQVIGGEEAEENGAMSLLQQGEQLLEENGDVLLSLQRAHERAVKENVKMATEISRLQQRLQKLEPESVMSSCLDEPATGLFGNSVEQTEPFLQPNRIKQAEGGTTQRILSDLQGDEVRDLESTGTSSGQRQVRVEESEASIESFSELENSEETRTETWDLKNQVGQLREQLMILRADCDRASEKKQDLLFDVSVLKKKLKMLERIPEASPKYKVLYEDASRENECLQEELRMMETRYDEALESNKELTSEMFRLQDELKKVEEMTDTFLSLEKSYKEIKRENEELHVLVLRLQGKIEKLRERAVLQCDCFSLWEAHLDNLEVGPDEKVFELNQTLDERVPNVMSVHHIIEEHLYQENQYLEQENTQLLEKVKAHEIAWLHGTLQTHRDKLGAQNQVVLEENTALLGLQDKHFQHQATIAELEREKKKLQELTRKLRERVTALVKQKDVPSQGEKEEELKAMMHDLQITCSEMQQKVELLRYESEKLQEENSILRNEITTLNEEDSISNLKLGKLSGSQEEMWQKIETVKQEKAAVQKMVENLKKQISELKTKNQQLDLENMKLSQKNSQNQKELQELNQRLAEMLSQKDKEPGHSACEEWEQEKSNLKEELEHCKLQSSTLVSSLEAELSEVKIQTHIVEQENLLLKDELEKVKQLCRCPDLSDFQQKISSILSHNEKLLKEKEALSEELNICVDKLAKSSLLEHRIATMKQEQKSWEHQSESLKSQLVASQEKVQNLEDTLQNVNLQMSRIKSDLRVTQQEKEALKQEVMSLHKQLQNASDKNWAPEIGIHPSGFHNQQQRLSWDKLDHLINEEQQLLWQENERVQTMVQNTKPELIHSREKVRQLESNLPSPKHQKHLNSSGTVKPTEQEKLSLKRECEQFQKERSPTNRKVSQMKSLERELETIHLENEGLKKKQVKLDEQLMEMQHLRSTVMLSPSPHAWELQLLQQQTCPVVPREQFLQLQRQLLQAERINQCLQEELENRTSETNTPQALLPEQRAVHADSYRRIGHL", "length": 2080, "header": "tr|E1BQ19-1|E1BQ19_BOVIN Computationally mapped isoform of Ninein OS=Bos taurus OX=9913 GN=NIN PE=4 SV=4 CANONICAL=E1BMB1-1" }, "locus": { "chromosome": "10", "start_pos": 43690547, "end_pos": 43600100, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027030.7", "url": "https://www.ensembl.org/id/ENSBTAT00000027030.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027030.7", "url": "https://www.ensembl.org/id/ENSBTAP00000027030.7" } ] } }, { "isoform_ac": "G3MYK5-1", "url": "https://www.uniprot.org/uniprotkb/G3MYK5/entry", "sequence": { "sequence": "MDEAEQDQHEARLKELFDSFDTTGTGSLGQEELTDLCHMLSLEEVAPVLQETLLQDNLLGRVHFDQFKEALILILSRTLSNEEHFQEPDCTLEAQPKYVRGGKRYGRRSLPEFQESVEEFAEVTVIEPLGEEAQPSHIPASERSEHWKTQRSEEYEAEGQLRFWNPDDLKASQTGSLAPQDWIEEKLQEVCEDLGITRDGHLNRKKLVSICEQYGLQNVDGEMLEEVFHNLDPDGMMSVEDFFYGLFKNGKPLTPSASTPYRQLKRHISMQSFDESGRRTTAPSAMMSTIGFRVFSCLDDGMGYASVERILDTWQEEGIENSQEILKALDFSLDGNVNLTELTLALENELLVTKNSIHQAALASFKAEIRHLLERVDQMLREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYKERIAALKNEFRKEREQILQQVGKQRLELEQEIEKAKTEENYVRDRLALSLKENSRLENELLENAEKLAEYESLTNKLQRNLENVLAEKFGDLDPSSAEFFLQEERLTQMRNEYEQQCRLLQDQVDELQSELQEYRTQGKVSRLPLQNSLSEELDINSGCIEPDQGLGSEECNPLNMSIEAELVIEQMKEQHHRELCHLRLELEDKVNYYEKQLDETKVAFEKEQENMKLKCENEVHILEEQISDLKNKIAELQGQTEVLKEAQHVAICRHEEEKKQLQMKWDEEKAHVQEELRLEHEMALRARLEQVEESFNRERERLVQNGAWTEEKVRGLTQKLEQVHQEQLKSLVEKHILEKEELQKELLEKHQRELHEGREKMETECNRRTSQIEAQFQADCQKVTERYEHALRSLEVHYRHQLKELLDQQCEERSQWEFEKDELTQECAEAQEQLKETLQREKATSLVLTQEREMLEKTYKEHLNSMVVEREQLLQDLEDLRKVSESQQSLLSNQILELKSSHERELKDREQILCQAGTSEQLVSQRLEQLQREHDQERQEMMSKLLVMESVHRATCEKADRERAEMSTEISRLQNKIKEMEQVVSPPSRLQNSCQVIGGEEAEENGAMSLLQQGEQLLEENGDVLLSLQRAHERAVKENVKMATEISRLQQRLQKLEPESVMSSCLDEPATGLFGNSVEQTEPFLQPNRIKQAEGGTTQRILSDLQGDEVRDLESTGTSSGQRQVRVEESEASIESFSELENSEETRTETWDLKNQVGQLREQLMILRADCDRASEKKQDLLFDVSVLKKKLKMLERIPEASPKYKVLYEDASRENECLQEELRMMETRYDEALESNKELTSEMFRLQDELKKVEEMTDTFLSLEKSYKEIKRENEELHVLVLRLQGKIEKLRERAVLQCDCFSLWEAHLDNLEVGPDEKVFELNQTLDERVPNVMSVHHIIEEHLYQENQYLEQENTQLLEKVKAHEIAWLHGTLQTHRDKLGAQNQVVLEENTALLGLQDKHFQHQATIAELEREKKKLQELTRKLRERVTALVKQKDVPSQGEKEEELKAMMHDLQITCSEMQQKVELLRYESEKLQEENSILRNEITTLNEEDSISNLKLGKLSGSQEEMWQKIETVKQEKAAVQKMVENLKKQISELKTKNQQLDLENMKLSQKNSQNQKELQELNQRLAEMLSQKDKEPGHSACEEWEQEKSNLKEELEHCKLQSSTLVSSLEAELSEVKIQTHIVEQENLLLKDELEKVKQLCRCPDLSDFQQKISSILSHNEKLLKEKEALSEELNICVDKLAKSSLLEHRIATMKQEQKSWEHQSESLKSQLVASQEKVQNLEDTLQNVNLQMSRIKSDLRVTQQEKEALKQEVMSLHKQLQNASDKNWAPEIGIHPSGFHNQQQRLSWDKLDHLINEEQQLLWQENERVQTMVQNTKPELIHSREKVRQLESNLPSPKHQKHLNSSGTVKPTEQEKLSLKRECEQFQKERSPTNRKVSQMKSLERELETIHLENEGLKKKQVKLDEQLMENSVVGTSREGCSSLPEIVCEDAAPEVHCDA", "length": 1993, "header": "tr|G3MYK5-1|G3MYK5_BOVIN Computationally mapped isoform of Ninein OS=Bos taurus OX=9913 GN=NIN PE=4 SV=2 CANONICAL=E1BMB1-1" }, "locus": { "chromosome": "10", "start_pos": 43690547, "end_pos": 43601935, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063401.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063401.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054640.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054640.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:510366", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:510366", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 13, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "E1BMB1", "url": "https://www.uniprot.org/uniprotkb/E1BMB1" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "E1BMB1", "url": "https://www.uniprot.org/uniprotkb/E1BMB1" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "E1BMB1", "url": "https://www.uniprot.org/uniprotkb/E1BMB1" } ], "pmid": "" }, { "name": "mitotic spindle pole", "id": "GO:0097431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097431", "evidence": [ { "database": "UniProtKB", "id": "E1BMB1", "url": "https://www.uniprot.org/uniprotkb/E1BMB1" } ], "pmid": "" }, { "name": "ciliary transition fiber", "id": "GO:0097539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097539", "evidence": [ { "database": "UniProtKB", "id": "E1BMB1", "url": "https://www.uniprot.org/uniprotkb/E1BMB1" } ], "pmid": "" }, { "name": "pericentriolar material", "id": "GO:0000242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000242", "evidence": [ { "database": "UniProtKB", "id": "E1BMB1", "url": "https://www.uniprot.org/uniprotkb/E1BMB1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BMB1", "url": "https://www.uniprot.org/uniprotkb/E1BMB1" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "E1BMB1", "url": "https://www.uniprot.org/uniprotkb/E1BMB1" } ], "pmid": "" }, { "name": "apical part of cell", "id": "GO:0045177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045177", "evidence": [ { "database": "UniProtKB", "id": "E1BMB1", "url": "https://www.uniprot.org/uniprotkb/E1BMB1" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "E1BMB1", "url": "https://www.uniprot.org/uniprotkb/E1BMB1" } ], "pmid": "" }, { "name": "cytoplasmic microtubule", "id": "GO:0005881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005881", "evidence": [ { "database": "UniProtKB", "id": "E1BMB1", "url": "https://www.uniprot.org/uniprotkb/E1BMB1" } ], "pmid": "" }, { "name": "axonal growth cone", "id": "GO:0044295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044295", "evidence": [ { "database": "UniProtKB", "id": "E1BMB1", "url": "https://www.uniprot.org/uniprotkb/E1BMB1" } ], "pmid": "" }, { "name": "centriolar subdistal appendage", "id": "GO:0120103", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120103", "evidence": [ { "database": "UniProtKB", "id": "E1BMB1", "url": "https://www.uniprot.org/uniprotkb/E1BMB1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "E1BMB1", "url": "https://www.uniprot.org/uniprotkb/E1BMB1" } ], "pmid": "" }, { "name": "microtubule minus-end binding", "id": "GO:0051011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051011", "evidence": [ { "database": "UniProtKB", "id": "E1BMB1", "url": "https://www.uniprot.org/uniprotkb/E1BMB1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "centrosome-templated microtubule nucleation", "id": "GO:0090222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090222", "evidence": [ { "database": "UniProtKB", "id": "E1BMB1", "url": "https://www.uniprot.org/uniprotkb/E1BMB1" } ], "pmid": "" }, { "name": "centrosome localization", "id": "GO:0051642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051642", "evidence": [ { "database": "UniProtKB", "id": "E1BMB1", "url": "https://www.uniprot.org/uniprotkb/E1BMB1" } ], "pmid": "" }, { "name": "microtubule anchoring at centrosome", "id": "GO:0034454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034454", "evidence": [ { "database": "UniProtKB", "id": "E1BMB1", "url": "https://www.uniprot.org/uniprotkb/E1BMB1" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "E1BMB1", "url": "https://www.uniprot.org/uniprotkb/E1BMB1" } ], "pmid": "" }, { "name": "centriole-centriole cohesion", "id": "GO:0010457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010457", "evidence": [ { "database": "UniProtKB", "id": "E1BMB1", "url": "https://www.uniprot.org/uniprotkb/E1BMB1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1368, "end_pos": 1370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1815, "end_pos": 1817, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1897, "end_pos": 1899, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2021, "end_pos": 2023, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2123, "end_pos": 2125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 602, "end_pos": 604, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1368, "end_pos": 1370 }, { "start_pos": 1815, "end_pos": 1817 }, { "start_pos": 1897, "end_pos": 1899 }, { "start_pos": 2021, "end_pos": 2023 }, { "start_pos": 2123, "end_pos": 2125 }, { "start_pos": 338, "end_pos": 340 }, { "start_pos": 602, "end_pos": 604 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1MDI4-1", "uniprot_ac": "F1MDI4", "uniprot_id": "F1MDI4_BOVIN", "mass": { "chemical_mass": 50903.0, "monoisotopic_mass": 50903.0 }, "refseq": {}, "gene_names": [ { "name": "BLNK", "type": "recommended", "evidence": [ { "id": "F1MDI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDI4" } ] } ], "protein_names": [ { "name": "B cell linker", "type": "synonym", "evidence": [ { "id": "F1MDI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDI4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1MDI4", "url": "https://www.uniprot.org/uniprotkb/F1MDI4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "BLNK", "url": "https://www.uniprot.org/uniprotkb/F1MDI4", "locus": { "chromosome": "26", "start_pos": 17515994, "end_pos": 17607169, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021358", "url": "https://www.ensembl.org/id/ENSBTAG00000021358" } ] } } ], "crossref": [ { "id": "F1MDI4", "url": "https://alphafold.ebi.ac.uk/entry/F1MDI4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021358", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021358", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09929", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09929", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "510393", "url": "https://www.ncbi.nlm.nih.gov/gene/510393", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ELLEDEX", "url": "https://omabrowser.org/oma/group/ELLEDEX/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M9A4", "url": "https://www.orthodb.org/?gene=A0A3Q1M9A4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MXN3", "url": "https://www.orthodb.org/?gene=A0A3Q1MXN3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1NIZ6", "url": "https://www.orthodb.org/?gene=A0A3Q1NIZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MDI4", "url": "https://www.orthodb.org/?gene=F1MDI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14098", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14098", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14098:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14098:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-983695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1M9A4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9A4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M9A4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9A4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MXN3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MXN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NIZ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NIZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NIZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NIZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SAW7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SAW7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T4N2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T4N2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T4N2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T4N2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TCU0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TCU0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCU0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MDI4", "url": "https://www.uniprot.org/uniprotkb/F1MDI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MDI4-1", "url": "https://www.uniprot.org/uniprotkb/F1MDI4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYAPESPADEEEQWSDDFDSDYENPDEHSDSEMYVLPAEEAGDDSYEPPPVEQETRTVHPALPFTRGEYVDNRSSQRQSPPFSKTLPSKPNWPSAKARLATSLPANTSLHKPQVPPKPKELLEDEADYVVPVEDEDENYIHPTEDSSVPSEKAPMVNRSIKPNNSSKSASPPGTAPGRKSGAWDSKSTSLPAAPSPLPRAGKKTAMPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQENMQSPVFPPPAQKAVHQKPIPLPRFPEGGSPTVDGPLPSFSSNSSLSEQEADVHCKPWYAGACDRKSAEEALYRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKTGEEYFGSVAEMIKNHQHNPLVLIDSQNNTKDSTRLKYAVKVS", "length": 459, "header": "tr|F1MDI4-1|F1MDI4_BOVIN Isoform 1 of B cell linker OS=Bos taurus OX=9913 GN=BLNK PE=4 SV=1 CANONICAL=F1MDI4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M9A4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9A4/entry", "sequence": { "sequence": "MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYAPESPADEEEQWSDDFDSDYENPDEHSDSEMYVLPAEEAGDDSYEPPPVEQETRTVHPALPFTRGEYVDNRSSQRQSPPFSKTLPSKPNWPSAKARLATSLPANTSLHKPQVPPKPKELLEDEADYVVPVEDEDENYIHPTEDSSVPSEKAPMVNRSIKPNNSSKSASPPGTAPGRKSGAWDSKSTSLPAAPSPLPRAGKKTAMPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQENMQSPVFPPPAQKAVHQKPIPLPRFPEGGSPTVDGPLPSFSSNSSLSEQEADVHCKPWYAGACDRKSAEEALYRSNKYFGSVAEMIKNHQHNPLVLIDSQNNTKDSTRLKYAVKVS", "length": 407, "header": "tr|A0A3Q1M9A4-1|A0A3Q1M9A4_BOVIN Computationally mapped isoform of B cell linker OS=Bos taurus OX=9913 GN=BLNK PE=4 SV=2 CANONICAL=F1MDI4-1" }, "locus": { "chromosome": "26", "start_pos": 17606961, "end_pos": 17516252, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085761.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085761.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070539.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070539.2" } ] } }, { "isoform_ac": "A0A3Q1MXN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXN3/entry", "sequence": { "sequence": "MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYAPESPADEEEQWSDDFTHRVHPPSGLDAHTFPQDTVQDSDYENPDEHSDSEMYVLPAEEAGDDSYEPPPVEQETRTVHPALPFTRGEYVDNRSSQRQSPPFSKTLPSKPNWPSAKARLATSLPANTSLHKPQVPPKPKELLEDEADYVVPVEDEDENYIHPTEDSSVPSEKAPMVNRSIKPNNSSKSASPPGTAPGRKSGAWDSKSTSLPAAPSPLPRAGKKTAMPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQENMQSPVFPPPAQKAVHQKPIPLPRFPEGGSPTVDGPLPSFSSNSSLSEQEADVHCKPWYAGACDRKSAEEALYRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKTGEEYFGSVAEMIKNHQHNPLVLIDSQNNTKDSTRLKYAVKVS", "length": 480, "header": "tr|A0A3Q1MXN3-1|F1MDI4_BOVIN Computationally mapped isoform of B cell linker OS=Bos taurus OX=9913 GN=BLNK PE=4 SV=1 CANONICAL=F1MDI4-1" }, "locus": { "chromosome": "26", "start_pos": 17606961, "end_pos": 17516252, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072550.2", "url": "https://www.ensembl.org/id/ENSBTAT00000072550.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060547.1", "url": "https://www.ensembl.org/id/ENSBTAP00000060547.1" } ] } }, { "isoform_ac": "A0A3Q1NIZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NIZ6/entry", "sequence": { "sequence": "MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYAPESPADEEEQWSDDFDSDYENPDEHSDSEMYVLPAEEAGDDSYEPPPVEQETRTVHPALPFTRGEYVDNRSSQRQSPPFSKTLPSKPNWPSAKARLATSLPANTSLHKPQVPPKPKELLEDEADYVVPVEDEDENYIHPTEDSSVPSEKGRKSGAWDSKSTSLPAAPSPLPRAGKKTAMPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQENMQSPVFPPPAQKAVHQKPIPLPRFPEGGSPTVDGPLPSFSSNSSLSEQEADVHCKPWYAGACDRKSAEEALYRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKTGEEYFGSVAEMIKNHQHNPLVLIDSQNNTKDSTRLKYAVKVS", "length": 435, "header": "tr|A0A3Q1NIZ6-1|A0A3Q1NIZ6_BOVIN Computationally mapped isoform of B cell linker OS=Bos taurus OX=9913 GN=BLNK PE=4 SV=2 CANONICAL=F1MDI4-1" }, "locus": { "chromosome": "26", "start_pos": 17606961, "end_pos": 17516252, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076556.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076556.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072046.2", "url": "https://www.ensembl.org/id/ENSBTAP00000072046.2" } ] } }, { "isoform_ac": "A0AAA9SAW7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAW7/entry", "sequence": { "sequence": "MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYAPESPADEEEQWSDDFDSDYENPDEHSDSEMYVLPAEEAGDDSYEPPPVEQETRTVHPALPFTRGEYVGRKSGAWDSKSTSLPAAPSPLPRAGKKTAMPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQENMQSPVFPPPAQKAVHQKPIPLPRFPEGGSPTVDGPLPSFSSNSSLSEQEADVHCKPWYAGACDRKSAEEALYRSNKYFGSVAEMIKNHQHNPLVLIDSQNNTKDSTRLKYAVKVS", "length": 301, "header": "tr|A0AAA9SAW7-1|A0AAA9SAW7_BOVIN Computationally mapped isoform of B cell linker OS=Bos taurus OX=9913 GN=BLNK PE=4 SV=1 CANONICAL=F1MDI4-1" }, "locus": { "chromosome": "26", "start_pos": 17606961, "end_pos": 17516252, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000126832.1", "url": "https://www.ensembl.org/id/ENSBTAT00000126832.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081048.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081048.1" } ] } }, { "isoform_ac": "A0AAA9T4N2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T4N2/entry", "sequence": { "sequence": "MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYAPDTCYLPNPK", "length": 63, "header": "tr|A0AAA9T4N2-1|A0AAA9T4N2_BOVIN Computationally mapped isoform of B cell linker OS=Bos taurus OX=9913 GN=BLNK PE=4 SV=1 CANONICAL=F1MDI4-1" }, "locus": { "chromosome": "26", "start_pos": 17606961, "end_pos": 17567737, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132042.1", "url": "https://www.ensembl.org/id/ENSBTAT00000132042.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092765.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092765.1" } ] } }, { "isoform_ac": "A0AAA9TCU0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCU0/entry", "sequence": { "sequence": "MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYAPESPADEEEQWSDDFDSDYENPDEHSDSEMYVLPAEEAGDDSYEPPPVEQETRTVHPALPFTRGTAPGRKSGAWDSKSTSLPAAPSPLPRAGKKTAMPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQENMQSPVFPPPAQKAVHQKPIPLPRFPEGGSPTVDGPLPSFSSNSSLSEQEADVHCKPWYAGACDRKSAEEALYRSNKYFGSVAEMIKNHQHNPLVLIDSQNNTKDSTRLKYAVKVS", "length": 301, "header": "tr|A0AAA9TCU0-1|A0AAA9TCU0_BOVIN Computationally mapped isoform of B cell linker OS=Bos taurus OX=9913 GN=BLNK PE=4 SV=1 CANONICAL=F1MDI4-1" }, "locus": { "chromosome": "26", "start_pos": 17606961, "end_pos": 17516252, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090158.1", "url": "https://www.ensembl.org/id/ENSBTAT00000090158.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095884.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095884.1" } ] } }, { "isoform_ac": "F1MDI4-1", "url": "https://www.uniprot.org/uniprotkb/F1MDI4/entry", "sequence": { "sequence": "MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYAPESPADEEEQWSDDFDSDYENPDEHSDSEMYVLPAEEAGDDSYEPPPVEQETRTVHPALPFTRGEYVDNRSSQRQSPPFSKTLPSKPNWPSAKARLATSLPANTSLHKPQVPPKPKELLEDEADYVVPVEDEDENYIHPTEDSSVPSEKAPMVNRSIKPNNSSKSASPPGTAPGRKSGAWDSKSTSLPAAPSPLPRAGKKTAMPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQENMQSPVFPPPAQKAVHQKPIPLPRFPEGGSPTVDGPLPSFSSNSSLSEQEADVHCKPWYAGACDRKSAEEALYRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKTGEEYFGSVAEMIKNHQHNPLVLIDSQNNTKDSTRLKYAVKVS", "length": 459, "header": "tr|F1MDI4-1|F1MDI4_BOVIN Isoform 1 of B cell linker OS=Bos taurus OX=9913 GN=BLNK PE=4 SV=1 CANONICAL=F1MDI4-1" }, "locus": { "chromosome": "26", "start_pos": 17606961, "end_pos": 17516252, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000056369.2", "url": "https://www.ensembl.org/id/ENSBTAT00000056369.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000051686.1", "url": "https://www.ensembl.org/id/ENSBTAP00000051686.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-983695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983695", "resource": "Reactome", "description": "Antigen activates B Cell Receptor (BCR) leading to generation of second messengers" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UGW7-1", "protein_name": "B cell linker", "gene_name": "BLNK", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDKLNKITVPASQKLRQLQKIVHDMKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVLPAEEAGDDSYEPPPAEQETRTVHPALPFTRGEYVDNRSSQRQSPPFSKTLPSKPSWPSAKARLVALPAAATLPAPTSLPKPQVPPKPKDLLEDEADYVVPVEDEDENYIHPTEDSSPPSEKAPMVNRSTKPNNSSKPASPPGTASGRSSGAWDSKSTSSPAAPSPLPRAGKKPAMQLKTTPVASQQNASSVCEERPIPAERHRGSSHRQENMQSPVFPPAQKPIHQKPIPLPRFPEGGSPTVDGPLPSFPSNSNLSEQEADVHCKPWYAGACDRKSAEEALYKSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYFGSVAEIIKNHQHSPLVLIDSQNNTKDSTRLKYAVKVS", "length": 463 }, "evidence": [ { "id": "F1MDI4", "url": "https://omabrowser.org/oma/group/F1MDI4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3GZU4-1", "protein_name": "B-cell linker protein isoform X1", "gene_name": "Blnk", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMDKIKKLKVKGPPSVPRRDYALDSPADEEERWSDDFDSDYENPDEHSDSEMYVMPAEETGDDSYEPPPAEQQTRVVHPALPFTRGEYVDNRSSQRHSPPFSKTLPSKPCWPSAKTRMTSTLPAPTCLQKPQIPPKPKDLLEDEADYVVPVEDHDENYIHPRESIPLPAEKAPMVNRSTKPNSCSKPMSPPGTVTGRNSGVWDSKSSLPAAPSPLPRAGKKTATPLKTTPVTSLPNASNVCEEKPVPAERHRGSSHRQDTVQSPVFPPTQKPIHQKPVPLPRFPEGGSPAVDGPLCSLSSNSTFADQEAELHGKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVAFFNKRVYNIPVRFIEATKQYALGKKKNGEEYFGSVVDIIQNHQHNPLVLIDSQNNTKDSTRLKYAVKVS", "length": 457 }, "evidence": [ { "id": "F1MDI4", "url": "https://omabrowser.org/oma/group/F1MDI4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q4KM52-1", "protein_name": "B-cell linker protein", "gene_name": "Blnk", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMDKIKKLKVKGPPSVPRRDYALDNPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEETGDDSYEPPPAEQQTRVVHPALPFTRGEYVDNRSSQRHSPPFSKTLPSKPSWPSAKARLASTLPAPNSLQKPQVPPKPKDLLEDEADYVVPVEDNDENYIHPRESSPLPAEKAPTVNRSTKPNSSSKHVSPPGTVAGRNSGVWDSKSSLPAAPSPLPRAGKKTATPLKTTPVPSLQNASNVCEEKPVPAERHRGSSHRQDTVQSPVFPPTQKPVLQKPVPLPRFTEGGSPAADGPVPSFPFNSTFADQEAELHGKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVAFFNKRVYNIPVRFIEATKQYALGKKKNGEEYFGSVVEIIKNHQHNPLVLIDSQNNTKDSTRLKYAVKVS", "length": 457 }, "evidence": [ { "id": "F1MDI4", "url": "https://omabrowser.org/oma/group/F1MDI4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8WV28-1", "protein_name": "B-cell linker protein", "gene_name": "BLNK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYFGSVAEIIRNHQHSPLVLIDSQNNTKDSTRLKYAVKVS", "length": 456 }, "evidence": [ { "id": "F1MDI4", "url": "https://omabrowser.org/oma/group/F1MDI4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QUN3-1", "protein_name": "B-cell linker protein", "gene_name": "Blnk", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMDKIKKLKVKGPPSVPRRDYALDSPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEETGDDSYEPPPAEQQTRVVHPALPFTRGEYVDNRSSQRHSPPFSKTLPSKPSWPSAKARLASTLPAPNSLQKPQVPPKPKDLLEDEADYVVPVEDNDENYIHPRESSPPPAEKAPMVNRSTKPNSSSKHMSPPGTVAGRNSGVWDSKSSLPAAPSPLPRAGKKPATPLKTTPVPPLPNASNVCEEKPVPAERHRGSSHRQDTVQSPVFPPTQKPVHQKPVPLPRFPEAGSPAADGPFHSFPFNSTFADQEAELLGKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVAFFNKRVYNIPVRFIEATKQYALGKKKNGEEYFGSVVEIVNSHQHNPLVLIDSQNNTKDSTRLKYAVKVS", "length": 457 }, "evidence": [ { "id": "F1MDI4", "url": "https://omabrowser.org/oma/group/F1MDI4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1MDI4", "url": "https://www.uniprot.org/uniprotkb/F1MDI4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1MDI4", "url": "https://www.uniprot.org/uniprotkb/F1MDI4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1MDI4", "url": "https://www.uniprot.org/uniprotkb/F1MDI4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "F1MDI4", "url": "https://www.uniprot.org/uniprotkb/F1MDI4" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "F1MDI4", "url": "https://www.uniprot.org/uniprotkb/F1MDI4" } ], "pmid": "" }, { "name": "B cell receptor signaling pathway", "id": "GO:0050853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050853", "evidence": [ { "database": "UniProtKB", "id": "F1MDI4", "url": "https://www.uniprot.org/uniprotkb/F1MDI4" } ], "pmid": "" }, { "name": "cell surface receptor protein tyrosine kinase signaling pathway", "id": "GO:0007169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007169", "evidence": [ { "database": "UniProtKB", "id": "F1MDI4", "url": "https://www.uniprot.org/uniprotkb/F1MDI4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "F1MDI4", "url": "https://www.uniprot.org/uniprotkb/F1MDI4" } ], "pmid": "" }, { "name": "SH2 domain binding", "id": "GO:0042169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042169", "evidence": [ { "database": "UniProtKB", "id": "F1MDI4", "url": "https://www.uniprot.org/uniprotkb/F1MDI4" } ], "pmid": "" }, { "name": "signaling adaptor activity", "id": "GO:0035591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035591", "evidence": [ { "database": "UniProtKB", "id": "F1MDI4", "url": "https://www.uniprot.org/uniprotkb/F1MDI4" } ], "pmid": "" }, { "name": "phospholipase binding", "id": "GO:0043274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043274", "evidence": [ { "database": "UniProtKB", "id": "F1MDI4", "url": "https://www.uniprot.org/uniprotkb/F1MDI4" } ], "pmid": "" }, { "name": "protein tyrosine kinase binding", "id": "GO:1990782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990782", "evidence": [ { "database": "UniProtKB", "id": "F1MDI4", "url": "https://www.uniprot.org/uniprotkb/F1MDI4" } ], "pmid": "" }, { "name": "molecular condensate scaffold activity", "id": "GO:0140693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140693", "evidence": [ { "database": "UniProtKB", "id": "F1MDI4", "url": "https://www.uniprot.org/uniprotkb/F1MDI4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 444, "end_pos": 446, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1MDI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDI4" }, { "id": "PS50001", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50001" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH2", "eco_id": "ECO_0000259", "start_pos": 349, "end_pos": 456, "start_aa": "Trp", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 }, { "start_pos": 156, "end_pos": 158 }, { "start_pos": 207, "end_pos": 209 }, { "start_pos": 213, "end_pos": 215 }, { "start_pos": 214, "end_pos": 216 }, { "start_pos": 268, "end_pos": 270 }, { "start_pos": 334, "end_pos": 336 }, { "start_pos": 444, "end_pos": 446 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BPJ0-1", "uniprot_ac": "E1BPJ0", "uniprot_id": "E1BPJ0_BOVIN", "mass": { "chemical_mass": 352547.0, "monoisotopic_mass": 352547.0 }, "refseq": { "ac": "XP_010803563", "name": "cilia- and flagella-associated protein 54 isoform X6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010803563" }, "gene_names": [ { "name": "CFAP54", "type": "recommended", "evidence": [ { "id": "E1BPJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPJ0" } ] }, { "name": "CFAP54", "type": "synonym", "evidence": [ { "id": "XP_010803563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010803563" } ] } ], "protein_names": [ { "name": "Cilia and flagella associated protein 54", "type": "synonym", "evidence": [ { "id": "E1BPJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPJ0/entry#names_and_taxonomy" } ] }, { "name": "cilia- and flagella-associated protein 54 isoform X6", "type": "synonym", "evidence": [ { "id": "XP_010803563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010803563" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BPJ0", "url": "https://www.uniprot.org/uniprotkb/E1BPJ0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CFAP54", "url": "https://www.uniprot.org/uniprotkb/E1BPJ0", "locus": { "chromosome": "5", "start_pos": 61065226, "end_pos": 60753133, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015792", "url": "https://www.ensembl.org/id/ENSBTAG00000015792" } ] } } ], "crossref": [ { "id": "ENSBTAG00000015792", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015792", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "787705", "url": "https://www.ncbi.nlm.nih.gov/gene/787705", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027912", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027912", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:787705", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:787705", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR33487", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33487", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33487:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33487:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14858", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14858", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010803563", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010803563", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1N6F8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N6F8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N6F8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N6F8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BPJ0", "url": "https://www.uniprot.org/uniprotkb/E1BPJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BPJ0-1", "url": "https://www.uniprot.org/uniprotkb/E1BPJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAQGTCSVSSPNVSPTSVSPPTPPPPSTGISKSTLVDSKASSLSPQSRSAGHEDLLPLAVFYGPLDAKNPLLASCEKEIQELLDFMKRKKALATTEEQKYEFHRLCATSLFNIWTKYAPRLPAAYYNEKLLKVGDSLCEMKEYKLALLQCYGRYLQEFSISFDENKADVNQFKTVFFPKGFGDKTAAHTFHALNGKNICNYQLVCDSDVNLQNKESVTHCLQILSSFRLIMQVALPQEHLCWIIFNGTIYIYTICRKLMIRGHSSKALEYLLWASICMESSVPLLSIRYLTWRATLYTAVCQCYYDCQAGVHGEAFARRALAKIDELRQLELMSSSQPQEESREYYREATIKMAVMIFKRGVFESRRKNKSFFRPKIRVNIKEAQTMPWPRTATEKLLEELFDSTASRFLAVLEALSDSNRRILQTGPVFTDEVEVRDVVSELFMAGKELLIMSNIGADGILDFPKAHLLELIIKKKNLISVNAAVKFIKLAFMYEEWSLFESAAGQLIDFLQRQDDPASKKAEKNLILLVAIEPLINVKRNKGLIFPFDNYKEGQVYVKKIAVHDTYVKSCGYSEDIFHLATTLYSCVCDSPQNAQPDKEIVVDMIMFLWQKCKLGMQRVTVSKNDYSKFTQKISTNKWLYLLWQINEIIHCYKMEDIDVVMVAEITLRLSEILESLGNPRRKFKKFLDVSLKRGTSEIFGGSKGSIDILPIIKKKPEEQLFMAYELLDKAIDGINLNCMLTALPNGSSVIDHCYATHNHYIDGDMCKPVTPNNFIMDLHLELIQAQHRIAVVLLDQLQVLQTPTVSKNTSTKGTEKLKKPASPDCFTELSVMNKIRKNKLSKAIYLMQKTLLIFEKDATCSSLQNYLTEAYSLIEKTESEQSIQYSYQKYVETAKRKKSRVPPPPILLSRTYRSVTLKPAPFVSDVKVCWYCILGRKAEGSYGKVRLNDNHLPNSGEAIPADGKSVFEVKGLETNEKYVFAVAAYCSKGKLIGDAIGETTKPILVYPPLSAVTTRMLLTQVAYQTGNYDLAKKVFSPVWDYFVASPPQGDQSIICLSNIMTITQRRLHSDILAESSSILLYLFLRNIFVTSDIKIKEENFFCDNIKGNEIFPSQQIARLIECERVLVALELSNYLNDSSYALQAVTQCYGLLAPIIYHNIVLVPVVQILIKCVVVLQGLPNVIHSKKHLASFESVQHMIACCIFYITKILRSWKEYDLAVMIINYGKKVLDISSGCKSLFGTTDLEEMQEEGSSKKSCKNKKPQQVLVPEKINEQLVLLETHLLKLTKQYITTELSGAEDPIFLYPIVLNWSVKGAVKEVMKFKQRPRFLEFFTQVMQKCMHDEKFQPMVEITNPVYDFLKRRNESLLGIKKLKYKDTLSKKVIKPVKKYRAAVVEIGKTTEMKQKKKAKRKETLREFLNKNPFISEMPEHERNKRADVRKVAHRFLVENLNPLILSYVKKKRFHQIFLEEMPWKAQMNLYLASAHFNLLLTKLGERTKIKFGSSPIMVSFRSCDPTMFSLYNSGTVLPTGRMTLENYKVMLDFLLTAKKRKAHLPSDAEEFLAFLNSKMSGENVSKTQTVYESDSQSGLSSKEKDRSANVGLLDHFMKIFLYCRRAMVLAHRGGYWTLLQNCCRALWNFTQELQILHKQAVDLYKTFPISQDSFLCISVLPFYLGAELLIDMLIELQNTDSIKTIDEKGEFSVPSCYGNIKNDNGGSSLTFEHPLDDVNVVDLKWIHDFVLKSLELVYQVEKWETLVSLAIQFNAVSHERYTEQVTPLLVYAQRQLLLQISKCKGPDISQQACVRYETEYKQKITCRNFIGIQLKINPPTNKGTAIGQRADVLRKLIYSEYSRAKELLCVPVDVTDTLRCFRETLEKSKYHNRSIRHSRKLLSLFLAQTQDVLQTSNQRSLHVQALHELGNLLIFAQKKRAAFKCWSQALDEIFRKEDVLHTWKEIGSSLTSATDGWSPPGSKDYSEELLSKGGIWGCLQGAVISAKIAQFIQTLDVEKRTNCCLLSALLFQGLLRTTLPHPKAERCYAQYEITQLLPGIELFSDRYRADICSVIASLYYVIRELHFAKQNLVILPLLALYQYFVSVICQDLVKNLEARILKIEVLTDLGFFSEAFHELSQIFYAKNTPSSVPTSCKPTGKMKLFQSFDSGKPLISKENLQALDDLINKGMPVILTTVSQQHLLNKFLVVKAYFFINVAATINCVPEQTMKPVGHGVMNEKSKPNLPNLKEMCLKDEGGSLCHLTKLKENFALSTLKSILLTEAEDRLNTLLSEMDHLSHKDLSQCSAGELEIVVEVRLQLAAIALQRHRAAYSAAIVFSTLKLLQDSKLFKKKVVEDDSENCTSSESYATESKDDNFLDPISLNSREYFNIHLWLRCRLALVTAFVAQIRGIGIVKENDITDYVSLINEVCVEAKAAGDRELQAEFLMQAVIIGLQEKHLKADIIKSLQEVIQLLEGHDFISPRSHLTLVRSMLLLDDLTKAEKFKETPFSKIEKLYLLTQSHNILIEQMITFGETIELPSSNTDYASPLLPLKNIYLPHVMLLAKTKMRIGHTVAKQVYYTSKKKDSSKWLPALHFFEIALKLARTSGTEEHEVEAEIFFQKGKIECQILMEEKPPTMQLESLFEAIQLSLRNDQNSGLIRDSYLEIALLFLHMRKLKSKLSVSPLMSIKALPRRHSSIKEPVVNKHEMYSLFAWIAIRAAAQVSEAVLAINLLIGKKNARTDTVSQGALSNIPEFASMDLLSSYTDYLLDNYQVVFQTGCTFSYVSEEIHEDVDSQKKNPIKVDITWILLLRYYIHLQRINNMSKLLASLKPGSGMSLPDDTLLTSLFNSGLILRQKEMHFFLKRFLQLYSSSCIDEFPKELFQVMEHPPVLEKVLYDSASKTGVTNASLCSDLSLKTVSSTLYGDVVPPVVATQALNKELCFQWYIPPLEKPPKETEPMVLLLYAYNMKPLNISDVASAACNCVYVGSFWVPLKRVISVHEKLSNLTQIAELSLPTTPKVTSNENLHEVEETEEKSIDAEMENMIIVCCNEIVSLFLGDEMATPLSEVPFDVSLPSIFSLERLFDLASGCIVSGGSLFNWVVSIIP", "length": 3104, "header": "tr|E1BPJ0-1|E1BPJ0_BOVIN Isoform 1 of Cilia and flagella associated protein 54 OS=Bos taurus OX=9913 GN=CFAP54 PE=4 SV=3 CANONICAL=E1BPJ0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1N6F8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N6F8/entry", "sequence": { "sequence": "MAAQGTCSVSSPNVSPTSVSPPTPPPPSTGISKSTLVDSKASSLSPQSRSAGHEDLLPLAVFYGPLDAKNPLLASCEKEIQELLDFMKRKKALATTEEQKYEFHRLCATSLFNIWTKYAPRLPAAYYNEKLLKVGDSLCEMKEYKLALLQCYGRYLQEFSISFDENKADVNQFKTVFFPKGFGDKTAAHTFHALNGKNICNYQLVCDSDVNLQNKESVTHCLQILSSFRLIMQVALPQEHLCWIIFNGTIYIYTICRKLMIRGHSSKALEYLLWASICMESSVPLLSIRYLTWRATLYTAVCQCYYDCQAGVHGEAFARRALAKIDELRQLELMSSSQPQEESREYYREATIKMAVMIFKRGVFESRRKNKSFFRPKIRVNIKEAQTMPWPRTATEKLLEELFDSTASRFLAVLEALSDSNRRILQTGPVFTDEVEVRDVVSELFMAGKELLIMSNIGADGILDFPKAHLLELIIKKKNLISVNAAVKFIKLAFMYEEWSLFESAAGQLIDFLQRQDDPASKKAEKNLILLVAIEPLINVKRNKGLIFPFDNYKEGQVYVKKIAVHDTYVKSCGYSEDIFHLATTLYSCVCDSPQNAQPDKEIVVDMIMFLWQKCKLGMQRVTVSKNDYSKFTQKISTNKWLYLLWQINEIIHCYKMEDIDVVMVAEITLRLSEILESLGNPRRKFKKFLDVSLKRGTSEIFGGSKGSIDILPIIKKKPEEQLFMAYELLDKAIDGINLNCMLTALPNGSSVIDHCYATHNHYIDGDMCKPVTPNNFIMDLHLELIQAQHRIAVVLLDQLQVLQTPTVSKNTSTKGTEKLKKPASPDCFTELSVMNKIRKNKLSKAIYLMQKTLLIFEKDATCSSLQNYLTEAYSLIEKTESEQSIQYSYQKYVETAKRKKSRVPPPPILLSRTYRSVTLKPAPFVSDVKVCWYCILGRKAEGSYGKVRLNDNHLPNSGEAIPADGKSVFEVKGLETNEKYVFAVAAYCSKGKLIGDAIGETTKPILVYPPLSAVTTRMLLTQVAYQTGNYDLAKKVFSPVWDYFVASPPQGDQSIICLSNIMTITQRRLHSDILAESSSILLYLFLRNIFVTSDIKIKEENFFCDNIKGNEIFPSQQIARLIECERVLVALELSNYLNDSSYALQAVTQCYGLLAPIIYHNIVLVPVVQILIKCVVVLQGLPNVIHSKKHLASFESVQHMIACCIFYITKILRSWKEYDLAVMIINYGKKVLDISSGCKSLFGTTDLEEMQEEGSSKKSCKNKKPQQVLVPEKINEQLVLLETHLLKLTKQYITTELSGAEDPIFLYPIVLNWSVKGAVKEVMKFKQRPRFLEFFTQVMQKCMHDEKFQPMVEITNPVYDFLKRRNESLLGIKKLKYKDTLSKKVIKPVKKYRAAVVEIGKTTEMKQKKKAKRKETLREFLNKNPFISEMPEHERNKRADVRKVAHRFLVENLNPLILSYVKKKRFHQIFLEEMPWKAQMNLYLASAHFNLLLTKLGERTKIKFGSSPIMVSFRSCDPTMFSLYNSGTVLPTGRMTLENYKVMLDFLLTAKKRKAHLPSDAEEFLAFLNSKMSGENVSKTQTVYESDSQSGLSSKEKDRSANVGLLDHFMKIFLYCRRAMVLAHRGGYWTLLQNCCRALWNFTQELQILHKQAVDLYKTFPISQDSFLCISVLPFYLGAELLIDMLIELQNTDSIKTIDEKGEFSVPSCYGNIKNDNGGSSLTFEHPLDDVNVVDLKWIHDFVLKSLELVYQVEKWETLVSLAIQFNAVSHERYTEQVTPLLVYAQRQLLLQISKCKGPDISQQACVRYETEYKQKITCRNFIGIQLKINPPTNKGTAIGQRADVLRKLIYSEYSRAKELLCVPVDVTDTLRCFRETLEKSKYHNRSIRHSRKLLSLFLAQTQGDKGGVNNLKFATGKVEFSMGTEEMHMPTPPDLSQEHFRVFSSVEKSKLPSSQLGLVISSYYETINVLQTSNQRSLHVQALHELGNLLIFAQKKRAAFKCWSQALDEIFRKEDVLHTWKEIGSSLTSATDGWSPPGSKDYSEELLSKGGIWGCLQGAVISAKIAQFIQTLDVEKRTNCCLLSALLFQGLLRTTLPHPKAERCYAQYEITQLLPGIELFSDRYRADICSVIASLYYVIRELHFAKQNLVILPLLALYQYFVSVICQDLVKNLEARILKIEVLTDLGFFSEAFHELSQIFYAKNTPSSVPTSCKPTGKMKLFQSFDSGKPLISKENLQALDDLINKGMPVILTTVSQQHLLNKFLVVKAYFFINVAATINCVPEQTMKPVGHGVMNEKSKPNLPNLKEMCLKDEGGSLCHLTKLKENFALSTLKSILLTEAEDRLNTLLSEMDHLSHKDLSQCSAGELEIVVEVRLQLAAIALQRHRAAYSAAIVFSTLKLLQDSKLFKKKVVEDDSENCTSSESYATESKDDNFLDPISLNSREYFNIHLWLRCRLALVTAFVAQIRGIGIVKENDITDYVSLINEVCVEAKAAGDRELQAEFLMQAVIIGLQEKHLKADIIKSLQEVIQLLEGHDFISPRSHLTLVRSMLLLDDLTKAEKFKETPFSKIEKLYLLTQSHNILIEQMITFGETIELPSSNTDYASPLLPLKNIYLPHVMLLAKTKMRIGHTVAKQVYYTSKKKDSSKWLPALHFFEIALKLARTSGTEEHEVEAEIFFQKGKIECQILMEEKPPTMQLESLFEAIQLSLRNDQNSGLIRDSYLEIALLFLHMRKLKSKLSVSPLMSIKALPRRHSSIKEPVVNKHEMYSLFAWIAIRAAAQVSEAVLAINLLIGKKNARTDTVSQGALSNIPEFASMDLLSSYTDYLLDNYQVVFQTGCTFSYVSEEIHEDVDSQKKNPIKVDITWILLLRYYIHLQRINNMSKLLASLKPGSGMSLPDDTLLTSLFNSGLILRQKEMHFFLKRFLQLYSSSCIDEFPKELFQVMEHPPVLEKVLYDSASKTGVTNASLCSDLSLKTVSSTLYGDVVPPVVATQALNKELCFQWYIPPLEKPPKETEPMVLLLYAYNMKPLNISDVASAACNCVYVGSFWVPLKRVISVHEKLSNLTQIAELSLPTTPKVTSNENLHEVEETEEKSIDAEMENMIIVCCNEIVSLFLGDEMATPLSEVPFDVSLPSIFSLERLFDLASGCIVSGGSLFNWVVSIIP", "length": 3169, "header": "tr|A0A3Q1N6F8-1|E1BPJ0_BOVIN Computationally mapped isoform of Cilia and flagella associated protein 54 OS=Bos taurus OX=9913 GN=CFAP54 PE=4 SV=2 CANONICAL=E1BPJ0-1" }, "locus": { "chromosome": "5", "start_pos": 61065017, "end_pos": 60753152, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084619.3", "url": "https://www.ensembl.org/id/ENSBTAT00000084619.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066048.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066048.2" } ] } }, { "isoform_ac": "E1BPJ0-1", "url": "https://www.uniprot.org/uniprotkb/E1BPJ0/entry", "sequence": { "sequence": "MAAQGTCSVSSPNVSPTSVSPPTPPPPSTGISKSTLVDSKASSLSPQSRSAGHEDLLPLAVFYGPLDAKNPLLASCEKEIQELLDFMKRKKALATTEEQKYEFHRLCATSLFNIWTKYAPRLPAAYYNEKLLKVGDSLCEMKEYKLALLQCYGRYLQEFSISFDENKADVNQFKTVFFPKGFGDKTAAHTFHALNGKNICNYQLVCDSDVNLQNKESVTHCLQILSSFRLIMQVALPQEHLCWIIFNGTIYIYTICRKLMIRGHSSKALEYLLWASICMESSVPLLSIRYLTWRATLYTAVCQCYYDCQAGVHGEAFARRALAKIDELRQLELMSSSQPQEESREYYREATIKMAVMIFKRGVFESRRKNKSFFRPKIRVNIKEAQTMPWPRTATEKLLEELFDSTASRFLAVLEALSDSNRRILQTGPVFTDEVEVRDVVSELFMAGKELLIMSNIGADGILDFPKAHLLELIIKKKNLISVNAAVKFIKLAFMYEEWSLFESAAGQLIDFLQRQDDPASKKAEKNLILLVAIEPLINVKRNKGLIFPFDNYKEGQVYVKKIAVHDTYVKSCGYSEDIFHLATTLYSCVCDSPQNAQPDKEIVVDMIMFLWQKCKLGMQRVTVSKNDYSKFTQKISTNKWLYLLWQINEIIHCYKMEDIDVVMVAEITLRLSEILESLGNPRRKFKKFLDVSLKRGTSEIFGGSKGSIDILPIIKKKPEEQLFMAYELLDKAIDGINLNCMLTALPNGSSVIDHCYATHNHYIDGDMCKPVTPNNFIMDLHLELIQAQHRIAVVLLDQLQVLQTPTVSKNTSTKGTEKLKKPASPDCFTELSVMNKIRKNKLSKAIYLMQKTLLIFEKDATCSSLQNYLTEAYSLIEKTESEQSIQYSYQKYVETAKRKKSRVPPPPILLSRTYRSVTLKPAPFVSDVKVCWYCILGRKAEGSYGKVRLNDNHLPNSGEAIPADGKSVFEVKGLETNEKYVFAVAAYCSKGKLIGDAIGETTKPILVYPPLSAVTTRMLLTQVAYQTGNYDLAKKVFSPVWDYFVASPPQGDQSIICLSNIMTITQRRLHSDILAESSSILLYLFLRNIFVTSDIKIKEENFFCDNIKGNEIFPSQQIARLIECERVLVALELSNYLNDSSYALQAVTQCYGLLAPIIYHNIVLVPVVQILIKCVVVLQGLPNVIHSKKHLASFESVQHMIACCIFYITKILRSWKEYDLAVMIINYGKKVLDISSGCKSLFGTTDLEEMQEEGSSKKSCKNKKPQQVLVPEKINEQLVLLETHLLKLTKQYITTELSGAEDPIFLYPIVLNWSVKGAVKEVMKFKQRPRFLEFFTQVMQKCMHDEKFQPMVEITNPVYDFLKRRNESLLGIKKLKYKDTLSKKVIKPVKKYRAAVVEIGKTTEMKQKKKAKRKETLREFLNKNPFISEMPEHERNKRADVRKVAHRFLVENLNPLILSYVKKKRFHQIFLEEMPWKAQMNLYLASAHFNLLLTKLGERTKIKFGSSPIMVSFRSCDPTMFSLYNSGTVLPTGRMTLENYKVMLDFLLTAKKRKAHLPSDAEEFLAFLNSKMSGENVSKTQTVYESDSQSGLSSKEKDRSANVGLLDHFMKIFLYCRRAMVLAHRGGYWTLLQNCCRALWNFTQELQILHKQAVDLYKTFPISQDSFLCISVLPFYLGAELLIDMLIELQNTDSIKTIDEKGEFSVPSCYGNIKNDNGGSSLTFEHPLDDVNVVDLKWIHDFVLKSLELVYQVEKWETLVSLAIQFNAVSHERYTEQVTPLLVYAQRQLLLQISKCKGPDISQQACVRYETEYKQKITCRNFIGIQLKINPPTNKGTAIGQRADVLRKLIYSEYSRAKELLCVPVDVTDTLRCFRETLEKSKYHNRSIRHSRKLLSLFLAQTQDVLQTSNQRSLHVQALHELGNLLIFAQKKRAAFKCWSQALDEIFRKEDVLHTWKEIGSSLTSATDGWSPPGSKDYSEELLSKGGIWGCLQGAVISAKIAQFIQTLDVEKRTNCCLLSALLFQGLLRTTLPHPKAERCYAQYEITQLLPGIELFSDRYRADICSVIASLYYVIRELHFAKQNLVILPLLALYQYFVSVICQDLVKNLEARILKIEVLTDLGFFSEAFHELSQIFYAKNTPSSVPTSCKPTGKMKLFQSFDSGKPLISKENLQALDDLINKGMPVILTTVSQQHLLNKFLVVKAYFFINVAATINCVPEQTMKPVGHGVMNEKSKPNLPNLKEMCLKDEGGSLCHLTKLKENFALSTLKSILLTEAEDRLNTLLSEMDHLSHKDLSQCSAGELEIVVEVRLQLAAIALQRHRAAYSAAIVFSTLKLLQDSKLFKKKVVEDDSENCTSSESYATESKDDNFLDPISLNSREYFNIHLWLRCRLALVTAFVAQIRGIGIVKENDITDYVSLINEVCVEAKAAGDRELQAEFLMQAVIIGLQEKHLKADIIKSLQEVIQLLEGHDFISPRSHLTLVRSMLLLDDLTKAEKFKETPFSKIEKLYLLTQSHNILIEQMITFGETIELPSSNTDYASPLLPLKNIYLPHVMLLAKTKMRIGHTVAKQVYYTSKKKDSSKWLPALHFFEIALKLARTSGTEEHEVEAEIFFQKGKIECQILMEEKPPTMQLESLFEAIQLSLRNDQNSGLIRDSYLEIALLFLHMRKLKSKLSVSPLMSIKALPRRHSSIKEPVVNKHEMYSLFAWIAIRAAAQVSEAVLAINLLIGKKNARTDTVSQGALSNIPEFASMDLLSSYTDYLLDNYQVVFQTGCTFSYVSEEIHEDVDSQKKNPIKVDITWILLLRYYIHLQRINNMSKLLASLKPGSGMSLPDDTLLTSLFNSGLILRQKEMHFFLKRFLQLYSSSCIDEFPKELFQVMEHPPVLEKVLYDSASKTGVTNASLCSDLSLKTVSSTLYGDVVPPVVATQALNKELCFQWYIPPLEKPPKETEPMVLLLYAYNMKPLNISDVASAACNCVYVGSFWVPLKRVISVHEKLSNLTQIAELSLPTTPKVTSNENLHEVEETEEKSIDAEMENMIIVCCNEIVSLFLGDEMATPLSEVPFDVSLPSIFSLERLFDLASGCIVSGGSLFNWVVSIIP", "length": 3104, "header": "tr|E1BPJ0-1|E1BPJ0_BOVIN Isoform 1 of Cilia and flagella associated protein 54 OS=Bos taurus OX=9913 GN=CFAP54 PE=4 SV=3 CANONICAL=E1BPJ0-1" }, "locus": { "chromosome": "5", "start_pos": 61065017, "end_pos": 60753152, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000043356.4", "url": "https://www.ensembl.org/id/ENSBTAT00000043356.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000040931.3", "url": "https://www.ensembl.org/id/ENSBTAP00000040931.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 23, "start_aa": "Thr", "end_pos": 23, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr23", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:787705", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:787705", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "E1BPJ0", "url": "https://www.uniprot.org/uniprotkb/E1BPJ0" } ], "pmid": "" }, { "name": "sperm flagellum assembly", "id": "GO:0120316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120316", "evidence": [ { "database": "UniProtKB", "id": "E1BPJ0", "url": "https://www.uniprot.org/uniprotkb/E1BPJ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1139, "end_pos": 1141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1313, "end_pos": 1315, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1367, "end_pos": 1369, "annotation": "n_glycosylation_sequon" }, { "start_pos": 13, "end_pos": 15, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1577, "end_pos": 1579, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1642, "end_pos": 1644, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1886, "end_pos": 1888, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2356, "end_pos": 2358, "annotation": "n_glycosylation_sequon" }, { "start_pos": 247, "end_pos": 249, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2819, "end_pos": 2821, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2904, "end_pos": 2906, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2970, "end_pos": 2972, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3003, "end_pos": 3005, "annotation": "n_glycosylation_sequon" }, { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" }, { "start_pos": 748, "end_pos": 750, "annotation": "n_glycosylation_sequon" }, { "start_pos": 811, "end_pos": 813, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 23 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1139, "end_pos": 1141 }, { "start_pos": 1313, "end_pos": 1315 }, { "start_pos": 1367, "end_pos": 1369 }, { "start_pos": 13, "end_pos": 15 }, { "start_pos": 1577, "end_pos": 1579 }, { "start_pos": 1642, "end_pos": 1644 }, { "start_pos": 1886, "end_pos": 1888 }, { "start_pos": 2356, "end_pos": 2358 }, { "start_pos": 247, "end_pos": 249 }, { "start_pos": 2819, "end_pos": 2821 }, { "start_pos": 2904, "end_pos": 2906 }, { "start_pos": 2970, "end_pos": 2972 }, { "start_pos": 3003, "end_pos": 3005 }, { "start_pos": 370, "end_pos": 372 }, { "start_pos": 748, "end_pos": 750 }, { "start_pos": 811, "end_pos": 813 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BND2-1", "uniprot_ac": "E1BND2", "uniprot_id": "E1BND2_BOVIN", "mass": { "chemical_mass": 97392.0, "monoisotopic_mass": 97392.0 }, "refseq": {}, "gene_names": [ { "name": "CEP104", "type": "recommended", "evidence": [ { "id": "E1BND2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BND2" } ] } ], "protein_names": [ { "name": "Centrosomal protein of 104 kDa", "type": "recommended", "evidence": [ { "id": "E1BND2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BND2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Required for ciliogenesis and for structural integrity at the ciliary tip.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFA0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFA0#function" }, { "database": "UniProtKB", "id": "ARBA00059645", "url": "https://www.uniprot.org/uniprotkb/ARBA00059645#function" }, { "database": "UniProtKB", "id": "E1BND2", "url": "https://www.uniprot.org/uniprotkb/E1BND2#function" }, { "database": "UniProtKB", "id": "A0A3Q1N7L6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N7L6#function" }, { "database": "UniProtKB", "id": "A0AAA9S0B6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0B6#function" }, { "database": "UniProtKB", "id": "A0AAA9TE48", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TE48#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BND2", "url": "https://www.uniprot.org/uniprotkb/E1BND2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CEP104", "url": "https://www.uniprot.org/uniprotkb/E1BND2", "locus": { "chromosome": "16", "start_pos": 49267318, "end_pos": 49228164, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020014", "url": "https://www.ensembl.org/id/ENSBTAG00000020014" } ] } } ], "crossref": [ { "id": "E1BND2", "url": "https://alphafold.ebi.ac.uk/entry/E1BND2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020014", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020014", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "785182", "url": "https://www.ncbi.nlm.nih.gov/gene/785182", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034085", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034085", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048738", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048738", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048739", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048739", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LFA0", "url": "https://www.orthodb.org/?gene=A0A3Q1LFA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1N7L6", "url": "https://www.orthodb.org/?gene=A0A3Q1N7L6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BND2", "url": "https://www.orthodb.org/?gene=E1BND2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13371", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13371", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13371:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13371:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21039", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21039", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21040", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21040", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LFA0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LFA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFA0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N7L6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N7L6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N7L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N7L6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0B6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0B6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0B6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0B6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TE48", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TE48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TE48-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TE48-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BND2", "url": "https://www.uniprot.org/uniprotkb/E1BND2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BND2-1", "url": "https://www.uniprot.org/uniprotkb/E1BND2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPHKIGFVVVSSSGHEDGFSARELMIHAPTVSGWRSPSYVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNVYNQVALVAVNIIGDPADFGDESNITSREKLIDHYLGHNAEDPALEGTCSGKSDYISPLDDLAFDMYQDPEVAQIIRRLDERKREAVQKERYDYAKKLKQAIADLQKVGERLGRYEVEKRCAVEKEDYDLAKEKKQQMERFRSRVYEQLQLHELVDAELMRRPLDLPLQPLACPSSPHHQPPMRSLPQPEERVSENRLADPFLQEKPSSHCLDVSPQRPTVDRPPPATDPPPKTHPDSLPYDERPLPVTRKQLGAAVSEAERRDVLGDEARRADTAGEPEPLTEKALREASSAVDVLGEALVAGAYSKTWSHREDALLTLHKQLTDTPVGTPKEDLKSTLRAAVFLVRRAIRDIVTPVFQASLKLLKMIITQYIPKHKLGRLETAHCVERTIPVLLTRTGDSSARLRVMASNFIQEIALFKEVKSLQVIPSYLVQPLKANSSTHLAMSQMALLARLLRDLGTEGAGFTVDSVMRFSVQALEHRVREVREAAVGMILDLYAQHRALVLEYLPPDDSTTRRNVLYKTIFEGFAKIDGRPTDAEMRAQKRAAAEEAEKRKKEEIRALQGQLAALKEMQAEVQEKESEATKAKNQDTQERKVAPPNAPEIPDNHYLDNLCIFCGERSESFTEEGLDLHYWKHCLMLTRCEHCRQVVEISSLTEHLLTECDQKDGFGRCYRCSEAVSKEELPRHVKTRDCNPAKSEKLANRCPLCHENFSPGEEAWKAHLMGPAGCTMNLRRTHVLHRTPVLPPGKGPAATRAGTSGSKVGSKIPTPKGGLSKGSSRTYTKR", "length": 867, "header": "tr|E1BND2-1|E1BND2_BOVIN Isoform 1 of Centrosomal protein of 104 kDa OS=Bos taurus OX=9913 GN=CEP104 PE=4 SV=2 CANONICAL=E1BND2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LFA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFA0/entry", "sequence": { "sequence": "MPHKIGFVVVSSSGHEDGFSARELMIHAPTVSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMIPSKVEFYISESLPEYFTPYQAERFRRLGYVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNVYNQVALVAVNIIGDPADFGDESNITSREKLIDHYLGHNAEDPALEGTCSGKSDYISPLDDLAFDMYQDPEVAQIIRRLDERKREAVQKERYDYAKKLKQAIADLQKVGERLGRYEVEKRCAVEKEDYDLAKEKKQQMERFRSRVYEQLQLHELVDAELMRRPLDLPLQPLACPSSPHHQPPMRSLPQPEERVSENRLADPFLQEKPSSHCLDVSPQRPTVDRPPPATDPPPKTHPDSLPYDERPLPVTRKQLGAAVSEAERRDVLGDEARRADTAGEPEPLTEKALREASSAVDVLGEALVAGAYSKTWSHREDALLTLHKQLTDTPVGTPKEDLKSTLRAAVFLVRRAIRDIVTPVFQASLKLLKMIITQYIPKHKLGRLETAHCVERTIPVLLTRTGDSSARLRVMASNFIQEIALFKEVKSLQVIPSYLVQPLKANSSTHLAMSQMALLARLLRDLGTEGAGFTVDSVMRFSVQALEHRVREVREAAVGMILDLYAQHRALVLEYLPPDDSTTRRNVLYKTIFEGFAKIDGRPTDAEMRAQKRAAAEEAEKRKKEEIRALQGQLAALKEMQAEVQEKESEATKAKNQDTQERKVAPPNAPEIPDNHYLDNLCIFCGERSESFTEEGLDLHYWKHCLMLTRCEHCRQVVEISSLTEHLLTECDQKDGFGRCYRCSEAVSKEELPRHVKTRDCNPAKSEKLANRCPLCHENFSPGEEVKAQPPPGQGPQDPRWEARSPPRRGA", "length": 883, "header": "tr|A0A3Q1LFA0-1|E1BND2_BOVIN Computationally mapped isoform of Centrosomal protein of 104 kDa OS=Bos taurus OX=9913 GN=CEP104 PE=4 SV=2 CANONICAL=E1BND2-1" }, "locus": { "chromosome": "16", "start_pos": 49266279, "end_pos": 49231883, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083185.3", "url": "https://www.ensembl.org/id/ENSBTAT00000083185.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056801.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056801.2" } ] } }, { "isoform_ac": "A0A3Q1N7L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N7L6/entry", "sequence": { "sequence": "MPHKIGFVVVSSSGHEDGFSARELMIHAPTVSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMIPSKVEFYISESLPEYFTPYQAERFRRLGYVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNVYNQVALVAVNIIGDPADFGDESNITSREKLIDHYLGHNAEDPALEGTCSGKSDYISPLDDLAFDMYQDPEVAQIIRRLDERKREAVQKERYDYAKKLKQAIADLQKMRRPLDLPLQPLACPSSPHHQPPMRSLPQPEERVSENRLADPFLQEKPSSHCLDVSPQRPTVDRPPPATDPPPKTHPDSLPYDERPLPVTRKQLGAAVSEAERRDVLGDEARRADTAGEPEPLTEKALREASSAVDVLGEALVAGAYSKTWSHREDALLTLHKQLTDTPVGTPKEDLKSTLRAAVFLVRRAIRDIVTPVFQASLKLLKMIITQYIPKHKLGRLETAHCVERTIPVLLTRTGDSSARLRVMASNFIQEIALFKEVKSLQVIPSYLVQPLKANSSTHLAMSQMALLARLLRDLGTEGAGFTVDSVMRFSVQALEHRVREVREAAVGMILDLYAQHRALVLEYLPPDDSTTRRNVLYKTIFEGFAKIDGRPTDAEMRAQKRAAAEEAEKRKKEEIRALQGQLAALKEMQAEVQEKESEATKAKNQDTQERKVAPPNAPEIPDNHYLDNLCIFCGERSESFTEEGLDLHYWKHCLMLTRCEHCRQVVEISSLTEHLLTECDQKDGFGRCYRCSEAVSKEELPRHVKTRDCNPAKSEKLANRCPLCHENFSPGEEAWKAHLMGPAGCTMNLRRTHVLHRTPVLPPGKGPAATRAGTSGSKVGSKIPTPKGGLSKGSSRTYTKR", "length": 873, "header": "tr|A0A3Q1N7L6-1|A0A3Q1N7L6_BOVIN Computationally mapped isoform of Centrosomal protein of 104 kDa OS=Bos taurus OX=9913 GN=CEP104 PE=4 SV=2 CANONICAL=E1BND2-1" }, "locus": { "chromosome": "16", "start_pos": 49266314, "end_pos": 49231883, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082802.3", "url": "https://www.ensembl.org/id/ENSBTAT00000082802.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066747.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066747.2" } ] } }, { "isoform_ac": "A0AAA9S0B6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0B6/entry", "sequence": { "sequence": "MPHKIGFVVVSSSGHEDGFSARELMIHAPTVSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMIPSKVEFYISESLPEYFTPYQAERFRRLGCVLSSSYVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNVYNQVALVAVNIIGDPADFGDESNITSREKLIDHYLGHNAEDPALEGTCSGKSDYISPLDDLAFDMYQDPEVAQIIRRLDERKREAVQKERYDYAKKLKQAIADLQKVGERLGRYEVEKRCAVEKEDYDLAKEKKQQMERFRSRVYEQLQLHELVDAELMRRPLDLPLQPLACPSSPHHQPPMRSLPQPEERVSENRLADPFLQEKPSSHCLDVSPQRPTVDRPPPATDPPPKTHPDSLPYDERPLPVTRKQLGAAVSEAERRDVLGDEARRADTAGEPEPLTEKALREASSAVDVLGEALVAGAYSKTWSHREDALLTLHKQLTDTPVGTPKEDLKSTLRAAVFLVRRAIRDIVTPVFQASLKLLKMIITQYIPKHKLGRLETAHCVERTIPVLLTRTGDSSARLRVMASNFIQEIALFKEVKSLQVIPSYLVQPLKANSSTHLAMSQMALLARLLRDLGTEGAGFTVDSVMRFSVQALEHRVREVREAAVGMILDLYAQHRALVLEYLPPDDSTTRRNVLYKTIFEGFAKIDGRPTDAEMRAQKRAAAEEAEKRKKEEIRALQGQLAALKEMQAEVQEKESEATKAKNQDTQERKVAPPNAPEIPDNHYLDNLCIFCGERSESFTEEGLDLHYWKHCLMLTRCEHCRQVVEISSLTEHLLTECDQKDGFGRCYRCSEAVSKEELPRHVKTRDCNPAKSEKLANRCPLCHENFSPGEEAWKAHLMGPAGCTMNLRRTHVLHRTPVLPPGKGPAATRAGTSGSKVGSKIPTPKGGLSKGSSRTYTKR", "length": 931, "header": "tr|A0AAA9S0B6-1|A0AAA9S0B6_BOVIN Computationally mapped isoform of Centrosomal protein of 104 kDa OS=Bos taurus OX=9913 GN=CEP104 PE=4 SV=1 CANONICAL=E1BND2-1" }, "locus": { "chromosome": "16", "start_pos": 49266314, "end_pos": 49231883, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000111457.2", "url": "https://www.ensembl.org/id/ENSBTAT00000111457.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078400.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078400.1" } ] } }, { "isoform_ac": "A0AAA9TE48-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TE48/entry", "sequence": { "sequence": "MPHKIGFVVVSSSGHEDGFSARELMIHAPTVSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMIPSKVEFYISESLPEYFTPYQAERFRRLGYVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNVYNQVALVAVNIIGDPADFGDESNITSREKLIDHYLGHNAEDPALEGTCSGKSDYISPLDDLAFDMYQDPEVAQIIRRLDERKREAVQKERYDYAKKLKQAIADLQKVGERLGRYEVEKRCAVEKEDYDLAKEKKQQMERFRSRVYEQLQLHELVDAELMRRPLDLPLQPLACPSSPHHQPPMRSLPQPEERVSENRLADPFLQEKPSSHCLDVSPQRPTVDRPPPATDPPPKTHVAGAYSKTWSHREDALLTLHKQLTDTPVGTPKEDLKSTLRAAVFLVRRAIRDIVTPVFQASLKLLKMIITQYIPKHKLGRLETAHCVERTIPVLLTRTGDSSARLRVMASNFIQEIALFKEVKSLQVIPSYLVQPLKANSSTHLAMSQMALLARLLRDLGTEGAGFTVDSVMRFSVQALEHRVREVREAAVGMILDLYAQHRALVLEYLPPDDSTTRRNVLYKTIFEGFAKIDGRPTDAEMRAQKRAAAEEAEKRKKEEIRALQGQLAALKEMQAEVQEKESEATKAKNQDTQERKVAPPNAPEIPDNHYLDNLCIFCGERSESFTEEGLDLHYWKHCLMLTRCEHCRQVVEISSLTEHLLTECDQKDGFGRCYRCSEAVSKEELPRHVKTRDCNPAKSEKLANRCPLCHENFSPGEEAWKAHLMGPAGCTMNLRRTHVLHRTPVLPPGKGPAATRAGTSGSKVGSKIPTPKGGLSKGSSRTYTKR", "length": 859, "header": "tr|A0AAA9TE48-1|A0AAA9TE48_BOVIN Computationally mapped isoform of Centrosomal protein of 104 kDa OS=Bos taurus OX=9913 GN=CEP104 PE=4 SV=1 CANONICAL=E1BND2-1" }, "locus": { "chromosome": "16", "start_pos": 49266314, "end_pos": 49231883, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000111466.2", "url": "https://www.ensembl.org/id/ENSBTAT00000111466.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096424.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096424.1" } ] } }, { "isoform_ac": "E1BND2-1", "url": "https://www.uniprot.org/uniprotkb/E1BND2/entry", "sequence": { "sequence": "MPHKIGFVVVSSSGHEDGFSARELMIHAPTVSGWRSPSYVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNVYNQVALVAVNIIGDPADFGDESNITSREKLIDHYLGHNAEDPALEGTCSGKSDYISPLDDLAFDMYQDPEVAQIIRRLDERKREAVQKERYDYAKKLKQAIADLQKVGERLGRYEVEKRCAVEKEDYDLAKEKKQQMERFRSRVYEQLQLHELVDAELMRRPLDLPLQPLACPSSPHHQPPMRSLPQPEERVSENRLADPFLQEKPSSHCLDVSPQRPTVDRPPPATDPPPKTHPDSLPYDERPLPVTRKQLGAAVSEAERRDVLGDEARRADTAGEPEPLTEKALREASSAVDVLGEALVAGAYSKTWSHREDALLTLHKQLTDTPVGTPKEDLKSTLRAAVFLVRRAIRDIVTPVFQASLKLLKMIITQYIPKHKLGRLETAHCVERTIPVLLTRTGDSSARLRVMASNFIQEIALFKEVKSLQVIPSYLVQPLKANSSTHLAMSQMALLARLLRDLGTEGAGFTVDSVMRFSVQALEHRVREVREAAVGMILDLYAQHRALVLEYLPPDDSTTRRNVLYKTIFEGFAKIDGRPTDAEMRAQKRAAAEEAEKRKKEEIRALQGQLAALKEMQAEVQEKESEATKAKNQDTQERKVAPPNAPEIPDNHYLDNLCIFCGERSESFTEEGLDLHYWKHCLMLTRCEHCRQVVEISSLTEHLLTECDQKDGFGRCYRCSEAVSKEELPRHVKTRDCNPAKSEKLANRCPLCHENFSPGEEAWKAHLMGPAGCTMNLRRTHVLHRTPVLPPGKGPAATRAGTSGSKVGSKIPTPKGGLSKGSSRTYTKR", "length": 867, "header": "tr|E1BND2-1|E1BND2_BOVIN Isoform 1 of Centrosomal protein of 104 kDa OS=Bos taurus OX=9913 GN=CEP104 PE=4 SV=2 CANONICAL=E1BND2-1" }, "locus": { "chromosome": "16", "start_pos": 49266314, "end_pos": 49231883, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000034094.6", "url": "https://www.ensembl.org/id/ENSBTAT00000034094.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000033995.4", "url": "https://www.ensembl.org/id/ENSBTAP00000033995.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "E1BND2", "url": "https://www.uniprot.org/uniprotkb/E1BND2" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "E1BND2", "url": "https://www.uniprot.org/uniprotkb/E1BND2" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "E1BND2", "url": "https://www.uniprot.org/uniprotkb/E1BND2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1BND2", "url": "https://www.uniprot.org/uniprotkb/E1BND2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 520, "end_pos": 522, "annotation": "n_glycosylation_sequon" }, { "start_pos": 793, "end_pos": 795, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BND2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BND2" }, { "id": "SM01349", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01349" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TOG", "eco_id": "ECO_0000259", "start_pos": 366, "end_pos": 619, "start_aa": "Ala", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 }, { "start_pos": 520, "end_pos": 522 }, { "start_pos": 793, "end_pos": 795 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1MHN4-1", "uniprot_ac": "F1MHN4", "uniprot_id": "F1MHN4_BOVIN", "mass": { "chemical_mass": 194809.0, "monoisotopic_mass": 194809.0 }, "refseq": { "ac": "XP_010815111", "name": "rapamycin-insensitive companion of mTOR isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010815111" }, "gene_names": [ { "name": "RICTOR", "type": "recommended", "evidence": [ { "id": "F1MHN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MHN4" } ] }, { "name": "RICTOR", "type": "synonym", "evidence": [ { "id": "XP_010815111", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010815111" } ] } ], "protein_names": [ { "name": "RPTOR independent companion of MTOR complex 2", "type": "synonym", "evidence": [ { "id": "F1MHN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MHN4/entry#names_and_taxonomy" } ] }, { "name": "rapamycin-insensitive companion of mTOR isoform X1", "type": "synonym", "evidence": [ { "id": "XP_010815111", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010815111" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1MHN4", "url": "https://www.uniprot.org/uniprotkb/F1MHN4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RICTOR", "url": "https://www.uniprot.org/uniprotkb/F1MHN4", "locus": { "chromosome": "20", "start_pos": 35498717, "end_pos": 35360041, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006697", "url": "https://www.ensembl.org/id/ENSBTAG00000006697" } ] } } ], "crossref": [ { "id": "ENSBTAG00000006697", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006697", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "527459", "url": "https://www.ncbi.nlm.nih.gov/gene/527459", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028268", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028268", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029451", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029451", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029453", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029453", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LHF6", "url": "https://www.orthodb.org/?gene=A0A3Q1LHF6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LYI0", "url": "https://www.orthodb.org/?gene=A0A3Q1LYI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MHN4", "url": "https://www.orthodb.org/?gene=F1MHN4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13298", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13298", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13298:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13298:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14663", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14663", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14664", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14664", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14665", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14665", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14666", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14666", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14668", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14668", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010815111", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010815111", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LHF6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LHF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHF6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LYI0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LYI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYI0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SLY8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SLY8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T6W4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T6W4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T6W4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T6W4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0L8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0L8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0L8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0L8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MHN4", "url": "https://www.uniprot.org/uniprotkb/F1MHN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MHN4-1", "url": "https://www.uniprot.org/uniprotkb/F1MHN4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAIGRGRSLKNLRIRGRNDSGEENVPLDLTREPSDNLREILQNVAKLQGVSNMRKLGHLNNFTKLLCDIGHSEEKLGFNYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKVLKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVANSLIAVGNDGLQERDRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKTRQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIINLCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQDSWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHISVRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFHEMKKRGPKPYSLHLDHIIQKAIATHQKRDQYLRAQKDIFVLKDTEEALLMNLRDSQVLQHKENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAKSKQLTVVGCQFTEFLLESEEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYFLFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKILTAATDACRLYATKHLRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACEDKANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVTKQLEKWHKEYNSKYVDLIEEQLNEALTTYRKPIDGDNYVRRSNQRLQRPHVYLPVHLYGQLVHHKTGCHLLEVQNIITELCHNVRTPDLDKWEEIKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCEVLSVRGTCVYVLGLIAKTKQGCDILKCHNWDAVRHSRKHLWPVVPDDVEQLCNELSSVPSTLSLNSESTSSRHNSESESAPSSMFIMEDDRFGSSSTSTFFLDINEDAEPAFYDRPGPIKDKNPFPFFASSKLVKNRILNSLTLPNKKHRSSSDPKGGKLSSENKTSNRRIRTLTEPSVDFNHSDDFTPISTVQKTLQLETSFVGNKHIEDTGSTPSIGENDLKFTKSLGTENHKENTSRERLVVESSSSSHMKIRSQSFNTDTTTSGISSMSSSPSRETVGVDATTVDTDCGSMSTVVSTKTVKTSHYLTPQSNHLSLSKSSSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADYNFSYTSSRDAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSRINFKKKHVGGIRSLRPTITNNFFRFMKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSSATYGSSDDYIGLALPVDINDIFQVKDIPYFQTKNIPPHDDRGARVFAHDVGGLPSGTGGLVKNSFHLLRQQMSLTEIMNSIHSDASLFLESTEDTGLQEHTDDNCLYCVCIEILGFQPSNQLSAICSHSDLQDIPYSDWCEQTIHNPLEVVPSKFSGISGCSDGVSQEGSASSTKSTELLLGVKTIPDDTPMCRILLRKEVLRLVINLSSSVSTKCHETGLLTIKEKYPQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQDVQFLQMHEEAEAVLATPPKQTIVDTSAES", "length": 1732, "header": "tr|F1MHN4-1|F1MHN4_BOVIN Isoform 1 of RPTOR independent companion of MTOR complex 2 OS=Bos taurus OX=9913 GN=RICTOR PE=3 SV=3 CANONICAL=F1MHN4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LHF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHF6/entry", "sequence": { "sequence": "MAAIGRGRSLKNLRIRGRNDSGEENVPLDLTREPSDNLREILQNVAKLQGVSNMRKLGHLNNFTKLLCDIGHSEEKLGFNYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKVLKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVANSLIAVGNDGLQERDRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKTRQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIINLCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQDSWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHISVRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFHEMKKRGPKPYSLHLDHIIQKAIATHQKRDQYLRAQKDIFVLKDTEEALLMNLRDSQVLQHKENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAKSKQLTVVGCQFTEFLLESEEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYFLFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKILTAATDACRLYATKHLRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACEDKANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVTKQLEKWHKEYNSKYVDLIEEQLNEALTTYRKPIDGDNYVRRSNQRLQRPHVYLPVHLYGQLVHHKTGCHLLEVQGNIGSSNWGLNLLQEENVIPDILKLAKQCEVLSVRGTCVYVLGLIAKTKQGCDILKCHNWDAVRHSRKHLWPVVPDDVEQLCNELSSVPSTLSLNSESTSSRHNSESESAPSSMFIMEDDRFGSSSTSTFFLDINEDAEPAFYDRPGPIKDKNPFPFFASSKLVKNRILNSLTLPNKKHRSSSDPKGGKLSSENKTSNRRIRTLTEPSVDFNHSDDFTPISTVQKTLQLETSFVGNKHIEDTGSTPSIGENDLKFTKSLGTENHKENTSRERLVVESSSSSHMKIRSQSFNTDTTTSGISSMSSSPSRETVGVDATTVDTDCGSMSTVVSTKTVKTSHYLTPQSNHLSLSKSSSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADYNFSYTSSRDAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSRFMKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSSATYGSSDDYIGLALPVDINDIFQVKDIPYFQTKNIPPHDDRGARVFAHDVGGLPSGTGGLVKNSFHLLRQQMSLTEIMNSIHSDASLFLESTEDTGLQEHTDDNCLYCVCIEILGFQPSNQLSAICSHSDLQDIPYSDWCEQTIHNPLEVVPSKFSGISGCSDGVSQEGSASSTKSTELLLGVKTIPDDTPMCRILLRKEVLRLVINLSSSVSTKCHETGLLTIKEKYPQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQDVQFLQMHEEAEAVLATPPKQTIVDTSAES", "length": 1677, "header": "tr|A0A3Q1LHF6-1|F1MHN4_BOVIN Computationally mapped isoform of RPTOR independent companion of MTOR complex 2 OS=Bos taurus OX=9913 GN=RICTOR PE=3 SV=2 CANONICAL=F1MHN4-1" }, "locus": { "chromosome": "20", "start_pos": 35494331, "end_pos": 35360881, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072725.2", "url": "https://www.ensembl.org/id/ENSBTAT00000072725.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058162.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058162.2" } ] } }, { "isoform_ac": "A0A3Q1LYI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYI0/entry", "sequence": { "sequence": "MAAIGRGRSLKNLRIRGRNDSGEENVPLDLTREPSDNLREILQNVAKLQGVSNMRKLGHLNNFTKLLCDIGHSEEKLGFNYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKVLKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVANSLIAVGNDGLQERDRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKTRQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIINLCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQDSWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHISVRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFHEMKKRGPKPYSLHLDHIIQKAIATHQKRDQYLRAQKDIFVLKDTEEALLMNLRDSQVLQHKENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAKSKQLTVVGCQFTEFLLESEEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYFLFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKILTAATDACRLYATKHLRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACEDKANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVTKQLEKWHKEYNSKYVDLIEEQLNEALTTYRKPIDGDNYVRRSNQRLQRPHVYLPVHLYGQLVHHKTGCHLLEVQNIITELCHNVRTPDLDKWEEIKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCEVLSVRGTCVYVLGLIAKTKQGCDILKCHNWDAVRHSRKHLWPVVPDDVEQLCNELSSVPSTLSLNSESTSSRHNSESESAPSSMFIMEDDRFGSSSTSTFFLDINEDAEPAFYDRPGPIKDKNPFPFFASSKLVKNRILNSLTLPNKKHRSSSDPKGGKLSSENKTSNRRIRTLTEPSVDFNHSDDFTPISTVQKTLQLETSFVGNKHIEDTGSTPSIGENDLKFTKSLGTENHKENTSRERLVVESSSSSHMKIRSQSFNTDTTTSGISSMSSSPSRETVGVDATTVDTDCGSMSTVVSTKTVKTSHYLTPQSNHLSLSKSSSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADYNFSYTSSRDAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSRFMKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSSATYGSSDDYIGLALPVDINDIFQVKDIPYFQTKNIPPHDDRGARVFAHDVGGLPSGTGESTEDTGLQEHTDDNCLYCVCIEILGFQPSNQLSAICSHSDLQDIPYSDWCEQTIHNPLEVVPSKFSGISGCSDGVSQEGSASSTKSTELLLGVKTIPDDTPMCRILLRKEVLRLVINLSSSVSTKCHETGLLTIKEKYPQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQDVQFLQMHEEAEAVLATPPKQTIVDTSAES", "length": 1677, "header": "tr|A0A3Q1LYI0-1|A0A3Q1LYI0_BOVIN Computationally mapped isoform of RPTOR independent companion of MTOR complex 2 OS=Bos taurus OX=9913 GN=RICTOR PE=3 SV=2 CANONICAL=F1MHN4-1" }, "locus": { "chromosome": "20", "start_pos": 35494331, "end_pos": 35360881, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082990.2", "url": "https://www.ensembl.org/id/ENSBTAT00000082990.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062317.2", "url": "https://www.ensembl.org/id/ENSBTAP00000062317.2" } ] } }, { "isoform_ac": "A0AAA9SLY8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY8/entry", "sequence": { "sequence": "MGFPSWEMPPPGGRAPEGRARRGAFHPPSKALSRSRIGILFPPRPGRNDSGEENVPLDLTREPSDNLREILQNVAKLQGVSNMRKLGHLNNFTKLLCDIGHSEEKLGFNYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKVLKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVANSLIAVGNDGLQERDRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKTRQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIINLCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQDSWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHISVRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFHEMKKRGPKPYSLHLDHIIQKAIATHQKRDQYLRAQKDIFVLKDTEEALLMNLRDSQVLQHKENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAKSKQLTVVGCQFTEFLLESEEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYFLFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKILTAATDACRLYATKHLRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACEDKANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVTKQLEKWHKEYNSKYVDLIEEQLNEALTTYRKPIDGDNYVRRSNQRLQRPHVYLPVHLYGQLVHHKTGCHLLEVQNIITELCHNVRTPDLDKWEEIKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCEVLSVRGTCVYVLGLIAKTKQGCDILKCHNWDAVRHSRKHLWPVVPDDVEQLCNELSSVPSTLSLNSESTSSRHNSESESAPSSMFIMEDDRFGSSSTSTFFLDINEDAEPAFYDRPGPIKDKNPFPFFASSKLVKNRILNSLTLPNKKHRSSSDPKGGKLSSENKTSNRRIRTLTEPSVDFNHSDDFTPISTVQKTLQLETSFVGNKHIEDTGSTPSIGENDLKFTKSLGTENHKENTSRERLVVESSSSSHMKIRSQSFNTDTTTSGISSMSSSPSRETVGVDATTVDTDCGSMSTVVSTKTVKTSHYLTPQSNHLSLSKSSSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADYNFSYTSSRDAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSRFMKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSSATYGSSDDYIGLALPVDINDIFQVKDIPYFQTKNIPPHDDRGARVFAHDVGGLPSGTGGLVKNSFHLLRQQMSLTEIMNSIHSDASLFLESTEDTGLQEHTDDNCLYCVCIEILGFQPSNQLSAICSHSDLQDIPYSDWCEQTIHNPLEVVPSKFSGISGCSDGVSQEGSASSTKSTELLLGVKTIPDDTPMCRILLRKEVLRLVINLSSSVSTKCHETGLLTIKEKYPQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQDVQFLQMHEEAEAVLATPPKQTIVDTSAES", "length": 1737, "header": "tr|A0AAA9SLY8-1|A0AAA9SLY8_BOVIN Computationally mapped isoform of RPTOR independent companion of MTOR complex 2 OS=Bos taurus OX=9913 GN=RICTOR PE=3 SV=1 CANONICAL=F1MHN4-1" }, "locus": { "chromosome": "20", "start_pos": 35494331, "end_pos": 35360604, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129872.2", "url": "https://www.ensembl.org/id/ENSBTAT00000129872.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084909.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084909.1" } ] } }, { "isoform_ac": "A0AAA9T6W4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T6W4/entry", "sequence": { "sequence": "MAAIGRGRSLKNLRIRGRNDSGEENVPLDLTREPSDNLREILQNVAKLQGVSNMRKLGHLNNFTKLLCDIGHSEEKLGFNYEDIIIWCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVANSLIAVGNDGLQERDRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKTRQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIINLCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQDSWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHISVRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFHEMKKRGPKPYSLHLDHIIQKAIATHQKRDQYLRAQKDIFVLKDTEEALLMNLRDSQVLQHKENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAKSKQLTVVGCQFTEFLLESEEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYFLFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKILTAATDACRLYATKHLRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACEDKANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVTKQLEKWHKEYNSKYVDLIEEQLNEALTTYRKPIDGDNYVRRSNQRLQRPHVYLPVHLYGQLVHHKTGCHLLEVQNIITELCHNVRTPDLDKWEEIKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCEVLSVRGTCVYVLGLIAKTKQGCDILKCHNWDAVRHSRKHLWPVVPDDVEQLCNELSSVPSTLSLNSESTSSRHNSESESAPSSMFIMEDDRFGSSSTSTFFLDINEDAEPAFYDRPGPIKDKNPFPFFASSKLVKNRILNSLTLPNKKHRSSSDPKGGKLSSENKTSNRRIRTLTEPSVDFNHSDDFTPISTVQKTLQLETSFVGNKHIEDTGSTPSIGENDLKFTKSLGTENHKENTSRERLVVESSSSSHMKIRSQSFNTDTTTSGISSMSSSPSRETVGVDATTVDTDCGSMSTVVSTKTVKTSHYLTPQSNHLSLSKSSSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADYNFSYTSSRDAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSRFMKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSSATYGSSDDYIGLALPVDINDIFQVKDIPYFQTKNIPPHDDRGARVFAHDVGGLPSGTGGLVKNSFHLLRQQMSLTEIMNSIHSDASLFLESTEDTGLQEHTDDNCLYCVCIEILGFQPSNQLSAICSHSDLQDIPYSDWCEQTIHNPLEVVPSKFSGISGCSDGVSQEGSASSTKSTELLLGVKTIPDDTPMCRILLRKEVLRLVINLSSSVSTKCHETGLLTIKEKYPQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQDVQFLQMHEEAEAVLATPPKQTIVDTSAES", "length": 1664, "header": "tr|A0AAA9T6W4-1|A0AAA9T6W4_BOVIN Computationally mapped isoform of RPTOR independent companion of MTOR complex 2 OS=Bos taurus OX=9913 GN=RICTOR PE=3 SV=1 CANONICAL=F1MHN4-1" }, "locus": { "chromosome": "20", "start_pos": 35494331, "end_pos": 35360881, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097271.1", "url": "https://www.ensembl.org/id/ENSBTAT00000097271.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092492.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092492.1" } ] } }, { "isoform_ac": "A0ABI0P0L8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0L8/entry", "sequence": { "sequence": "MAAIGRGRSLKNLRIREPSDNLREILQNVAKLQGVSNMRKLGHLNNFTKLLCDIGHSEEKLGFNYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKVLKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVANSLIAVGNDGLQERDRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKTRQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIINLCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQDSWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHISVRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFHEMKKRGPKPYSLHLDHIIQKAIATHQKRDQYLRAQKDIFVLKDTEEALLMNLRDSQVLQHKENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAKSKQLTVVGCQFTEFLLESEEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYFLFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKILTAATDACRLYATKHLRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACEDKANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVTKQLEKWHKEYNSKYVDLIEEQLNEALTTYRKPIDGDNYVRRSNQRLQRPHVYLPVHLYGQLVHHKTGCHLLEVQNIITELCHNVRTPDLDKWEEIKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCEVLSVRGTCVYVLGLIAKTKQGCDILKCHNWDAVRHSRKHLWPVVPDDVEQLCNELSSVPSTLSLNSESTSSRHNSESESAPSSMFIMEDDRFGSSSTSTFFLDINEDAEPAFYDRPGPIKDKNPFPFFASSKLVKNRILNSLTLPNKKHRSSSDPKGGKLSSENKTSNRRIRTLTEPSVDFNHSDDFTPISTVQKTLQLETSFVGNKHIEDTGSTPSIGENDLKFTKSLGTENHKENTSRERLVVESSSSSHMKIRSQSFNTDTTTSGISSMSSSPSRETVGVDATTVDTDCGSMSTVVSTKTVKTSHYLTPQSNHLSLSKSSSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADYNFSYTSSRDAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSRFMKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSSATYGSSDDYIGLALPVDINDIFQVKDIPYFQTKNIPPHDDRGARVFAHDVGGLPSGTGGLVKNSFHLLRQQMSLTEIMNSIHSDASLFLESTEDTGLQEHTDDNCLYCVCIEILGFQPSNQLSAICSHSDLQDIPYSDWCEQTIHNPLEVVPSKFSGISGCSDGVSQEGSASSTKSTELLLGVKTIPDDTPMCRILLRKEVLRLVINLSSSVSTKCHETGLLTIKEKYPQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQDVQFLQMHEEAEAVLATPPKQTIVDTSAES", "length": 1692, "header": "tr|A0ABI0P0L8-1|A0ABI0P0L8_BOVIN Computationally mapped isoform of RPTOR independent companion of MTOR complex 2 OS=Bos taurus OX=9913 GN=RICTOR PE=3 SV=1 CANONICAL=F1MHN4-1" }, "locus": { "chromosome": "20", "start_pos": 35494331, "end_pos": 35360881, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137866.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137866.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107744.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107744.1" } ] } }, { "isoform_ac": "F1MHN4-1", "url": "https://www.uniprot.org/uniprotkb/F1MHN4/entry", "sequence": { "sequence": 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"url": "https://www.uniprot.org/uniprotkb/F1MDC1/entry#names_and_taxonomy" } ] }, { "name": "ribosome-binding protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024856794", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024856794" } ] } ], "function": [ { "annotation": "Acts as a ribosome receptor and mediates interaction between the ribosome and the endoplasmic reticulum membrane.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LHT7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHT7#function" }, { "database": "UniProtKB", "id": "ARBA00053537", "url": "https://www.uniprot.org/uniprotkb/ARBA00053537#function" }, { "database": "UniProtKB", "id": "F1MDC1", "url": "https://www.uniprot.org/uniprotkb/F1MDC1#function" }, { "database": "UniProtKB", "id": "A0AAA9RXD6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXD6#function" }, { "database": "UniProtKB", "id": "A0AAA9S0L7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0L7#function" }, { "database": "UniProtKB", "id": "A0AAA9S5D2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5D2#function" }, { "database": "UniProtKB", "id": "A0AAA9SF38", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SF38#function" }, { "database": "UniProtKB", "id": "A0AAA9SIW4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIW4#function" }, { "database": "UniProtKB", "id": "A0AAA9SRN3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SRN3#function" }, { "database": "UniProtKB", "id": "A0AAA9U0D2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0D2#function" }, { "database": "UniProtKB", "id": "A0AAA9TMZ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMZ4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1MDC1", "url": "https://www.uniprot.org/uniprotkb/F1MDC1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RRBP1", "url": "https://www.uniprot.org/uniprotkb/F1MDC1", "locus": { "chromosome": "13", "start_pos": 37983813, "end_pos": 38032583, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015438", "url": "https://www.ensembl.org/id/ENSBTAG00000015438" } ] } } ], "crossref": [ { "id": "505941", "url": "https://www.ncbi.nlm.nih.gov/gene/505941", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007794", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007794", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040248", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040248", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LHT7", "url": "https://www.orthodb.org/?gene=A0A3Q1LHT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18939", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18939", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18939:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18939:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05104", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05104", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024856794", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024856794", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LHT7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LHT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHT7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RXD6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RXD6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXD6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0L7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0L7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0L7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0L7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S5D2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5D2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S5D2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5D2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SF38", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SF38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SF38-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SF38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SIW4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SIW4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SRN3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SRN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SRN3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SRN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TMZ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TMZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U0D2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0D2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U0D2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0D2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MDC1", "url": "https://www.uniprot.org/uniprotkb/F1MDC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MDC1-1", "url": "https://www.uniprot.org/uniprotkb/F1MDC1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTNHQKVEKKKKEKTVEKKGKTKKKEEKPNGKIPDHEPTPGVTILPKDPVWAPAVAVAPTSVQSPVVTAPVATVSAMPQEKLASSPKDKKKKEKKVAKVEPAVSSVVNSIQVLASKAAILEAAPKEVPMVVVSPVGAKGSAPATSSTQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKSEGAQNQGKKSEGAQNQGKKAEGAQNQGKKVEGAQNQGKKAEGAQNQGKKVEGAQNQGKKAEGAQNQGKKSEGAQNQGKKGEGAQNQGKKAEGAQNQGKKSEGAQNQGKKSEGTPNQSKKVEGAQNQGKKTEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKSEGAQNQGKKAEGTPNQGKKAEGAQNQGKKVEGAQNQGKKAEGNQNQGKKSEGTPNQGKKAEGGQNQGKKSEGAQNQGRKAEGAQNQGKKAEGAQNQGKKAEGNQNQGKKAEGNQNQGRKEQSTLDQGKMVEVVQNQSKKADGTPNQGKKAEGAQNQGRKAEGTPNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGRKVEAGQNQGKKADSVANQGTKVEGIANQGKKADGTPNQGKKAEGTSNQGKKSEGSPNQGKKVDASANQGKKAESAPTQGKNADMVQSQEAPKQEAPAKKKSGSKKKGEPGPPDANGTLHLPYKTLVSAVGSMVLSEGEAQRLMEILADKAGIVQDTWHKATQKGDPVVILKRQLEEKEKLLATEQEDAAVAKSKLRELNKELAAEKAKAAAGEAKVKKQLVAREQEITAVQARMQASYREHVKEVQQLQGKIRTLQEQLENGPSAQLARLQQENSILRDALNQATSQVESKQNTELAKLRQELGKVSKELVEKSEAVRQEEQQRKALEAKAAAVEKQVLQLQASHKESEEALQKRLDEVSRELCRAQSSHASLRADAEKAREQQQQMAELHGKLQSSEAEVRGKCEELRGLHGQLDEARAQNSQLTERIRSIEALLEASQAQDAQASRVEADQQQARLMELESQVWCLEKEATELREAVEQQKAKNNDLREKNWKAMEALASAEKSCEEKLRSLTQAKEESEKQLSLTEAQTKEALLALLPGLPTSTNQSYAEWLQELKENACLELSKRPQASPEPSDLAAKLREAEETQSGLQAECDQYRSILAETEAMLKALQKSVEEEEQVWKARVSAAEEELQESRVTVKHLEEVVEKLKGELESSDQVREHTWRLEAELEKHVAAASAECQSYAQEVAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQLSEMKSHVEDGDVAEAPRAEQDPAELKTQLERTEALLGDEQTRRQKLTAEFEEAQLVASQLQAELEKLRCTSALGSSEVEEAAQLKERLEKEKKLTGDLGRAATKLQELLKTTQEQLAKEKDTVQKLQERLDRPEDGSSKEGTSV", "length": 1551, "header": "tr|F1MDC1-1|F1MDC1_BOVIN Isoform 1 of Ribosome-binding protein 1 OS=Bos taurus OX=9913 GN=RRBP1 PE=1 SV=5 CANONICAL=F1MDC1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LHT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHT7/entry", "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTNHQKVEKKKKEKTVEKKGKTKKKEEKPNGKIPDHEPTPGVTILPKDPVWAPAVAVAPTSVQSPVVTAPVATVSAMPQEKLASSPKDKKKKEKKVAKVEPAVSSVVNSIQVLASKAAILEAAPKEVPMVVVSPVGAKGSAPATSSTQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKSEGAQNQGKKSEGAQNQGKKAEGAQNQGKKVEGAQNQGKKAEGAQNQGKKVEGAQNQGKKAEGAQNQGKKSEGAQNQGKKGEGAQNQGKKAEGAQNQGKKSEGAQNQGKKSEGTPNQSKKVEGAQNQGKKTEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKSEGAQNQGKKAEGTPNQGKKAEGAQNQGKKVEGAQNQGKKAEGNQNQGKKSEGTPNQGKKAEGGQNQGKKSEGAQNQGRKAEGAQNQGKKAEGAQNQGKKAEGNQNQGKKAEGNQNQGRKEQSTLDQGKMVEVVQNQSKKADGTPNQGKKAEGAQNQGRKAEGTPNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGRKVEAGQNQGKKADSVANQGTKVEGIANQGKKADGTPNQGKKAEGTSNQGKKSEGSPNQGKKVDASANQGKKAESAPTQGKNADMVQSQEAPKQEAPAKKKSGSKKKGEPGPPDANGTLHLPYKTLVSAVGSMVLSEGEAQRLMEILADKAGIVQDTWHKATQKGDPVVILKRQLEEKEKLLATEQEDAAVAKSKLRELNKELAAEKAKAAAGEAKVKKQLVAREQEITAVQARMQASYREHVKEVQQLQGKIRTLQEQLENGPSAQLARLQQENSILRDALNQATSQVESKQNTELAKLRQELGKVSKELVEKSEAVRQEEQQRKALEAKAAAVEKQVLQLQASHKESEEALQKRLDEVSRELCRAQSSHASLRADAEKAREQQQQMAELHGKLQSSEAEVRGKCEELRGLHGQLDEARAQNSQLTERIRSIEALLEASQAQDAQASRVEADQQQARLMELESQVWCLEKEATELREAVEQQKAKNNDLREKNWKAMEALASAEKSCEEKLRSLTQAKEESEKQLSLTEAQTKEALLALLPGLPTSTNQSYAEWLQELKENACLELSKRPQASPEPSDLAAKLREAEETQSGLQAECDQYRSILAETEAMLKALQKSVEEEEQVWKARVSAAEEELQESRVTVKHLEEVVEKLKGELESSDQLRQLLLESQSQLDAAKSEAQKQSDELALVRQQLSEMKSHVEDGDVAEAPRAEQDPAELKTQLERTEALLGDEQTRRQKLTAEFEEAQLVASQLQAELEKLRCTSALGSSEVEEAAQLKERLEKEKKLTGDLGRAATKLQELLKTTQEQLAKEKDTVQKLQERLDRPEDGSSKEGTSV", "length": 1519, "header": "tr|A0A3Q1LHT7-1|F1MDC1_BOVIN Computationally mapped isoform of Ribosome-binding protein 1 OS=Bos taurus OX=9913 GN=RRBP1 PE=1 SV=2 CANONICAL=F1MDC1-1" }, "locus": { "chromosome": "13", "start_pos": 38011390, "end_pos": 37984817, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069983.2", "url": "https://www.ensembl.org/id/ENSBTAT00000069983.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058395.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058395.2" } ] } }, { "isoform_ac": "A0AAA9RXD6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXD6/entry", "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTNHQKVEKKKKEKTVEKKGKTKKKEEKPNGKIPDHEPTPGVTILPKDPVWAPAVAVAPTSVQSPVVTAPVATVSAMPQEKLASSPKDKKKKEKKVAKVEPAVSSVVNSIQVLASKAAILEAAPKEVPMVVVSPVGAKGSAPATSSTQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKSEGAQNQGKKSEGAQNQGKKAEGAQNQGKKVEGAQNQGKKAEGAQNQGKKVEGAQNQGKKAEGAQNQGKKSEGAQNQGKKGEGAQNQGKKAEGAQNQGKKSEGTPNQSKKVEGAQNQGKKTEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGTPNQGKKAEGAQNQGKKVEGAQNQGKKAEGNQNQGKKSEGTPNQGKKAEGGQNQGKKSEGAQNQGRKAEGAQNQGKKAEGAQNQGKKAEGNQNQGKKAEGNQNQGRKEQSTLDQGKMVEVVQNQSKKADGTPNQGKKAEGAQNQGRKAEGTPNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGRKVEAGQNQGKKADSVANQGTKVEGIANQGKKADGTPNQGKKAEGTSNQGKKSEGSPNQGKKVDASANQGKKAESAPTQGKNADMVQSQEAPKQEAPAKKKSGSKKKGEPGPPDANGTLHLPYKTLVSAVGSMVLSEGEAQRLMEILADKAGIVQDTWHKATQKGDPVVILKRQLEEKEKLLATEQEDAAVAKSKLRELNKELAAEKAKAAAGEAKVKKQLVAREQEITAVQARMQASYREHVKEVQQLQGKIRTLQEQLENGPSAQLARLQQENSILRDALNQATSQVESKQNTELAKLRQELGKVSKELVEKSEAVRQEEQQRKALEAKAAAVEKQVLQLQASHKESEEALQKRLDEVSRELCRAQSSHASLRADAEKAREQQQQMAELHGKLQSSEAEVRGKCEELRGLHGQLDEARAQNSQLTERIRSIEALLEASQAQDAQASRVEADQQQARLMELESQVWCLEKEATELREAVEQQKAKNNDLREKNWKAMEALASAEKSCEEKLRSLTQAKEESEKQLSLTEAQTKEALLALLPGLPTSTNQSYAEWLQELKENACLELSKRPQASPEPSDLAAKLREAEETQSGLQAECDQYRSILAETEAMLKALQKSVEEEEQVWKARVSAAEEELQESRVTVKHLEEVVEKLKGELESSDQVREHTWRLEAELEKHVAAASAECQSYAQEVAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQLSEMKSHVEDGDVAEAPRAEQDPAELKTQLERTEALLGDEQTRRQKLTAEFEEAQLVASQLQAELEKLRCTSALGSSEVEEAAQLKERLEKEKKLTGDLGRAATKLQELLKTTQEQLAKEKDTVQKLQERLDRPEDGSSKEGTSV", "length": 1511, "header": "tr|A0AAA9RXD6-1|A0AAA9RXD6_BOVIN Computationally mapped isoform of Ribosome-binding protein 1 OS=Bos taurus OX=9913 GN=RRBP1 PE=1 SV=1 CANONICAL=F1MDC1-1" }, "locus": { "chromosome": "13", "start_pos": 38011390, "end_pos": 37984817, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124138.1", "url": "https://www.ensembl.org/id/ENSBTAT00000124138.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075809.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075809.1" } ] } }, { "isoform_ac": "A0AAA9S0L7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0L7/entry", "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTNHQKVEKKKKEKTVEKKGKTKKKEEKPNGKIPDHEPTPGVTILPKDPVWAPAVAVAPTSVQSPVVTAPVATVSAMPQEKLASSPKDKKKKEKKVAKVEPAVSSVVNSIQVLASKAAILEAAPKEVPMVVVSPVGAKGSAPATSSTQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKSEGAQNQGKKSEGAQNQGKKAEGAQNQGKKVEGAQNQGKKAEGAQNQGKKSEGAQNQGKKGEGAQNQGKKAEGAQNQGKKSEGAQNQGKKSEGTPNQSKKVEGAQNQGKKTEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKSEGAQNQGKKAEGTPNQGKKAEGAQNQGKKVEGAQNQGKKAEGNQNQGKKSEGTPNQGKKAEGGQNQGKKSEGAQNQGRKAEGAQNQGKKAEGAQNQGKKAEGNQNQGKKAEGNQNQGRKEQSTLDQGKMVEVVQNQSKKADGTPNQGKKAEGAQNQGRKAEGTPNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGRKVEAGQNQGKKADSVANQGTKVEGIANQGKKADGTPNQGKKAEGTSNQGKKSEGSPNQGKKVDASANQGKKAESAPTQGKNADMVQSQEAPKQEAPAKKKSGSKKKGEPGPPDANGTLHLPYKTLVSAVGSMVLSEGEAQRLMEILADKAGIVQDTWHKATQKGDPVVILKRQLEEKEKLLATEQEDAAVAKSKLRELNKELAAEKAKAAAGEAKVKKQLVAREQEITAVQARMQASYREHVKEVQQLQGKIRTLQEQLENGPSAQLARLQQENSILRDALNQATSQVESKQNTELAKLRQELGKVSKELVEKSEAVRQEEQQRKALEAKAAAVEKQVLQLQASHKESEEALQKRLDEVSRELCRAQSSHASLRADAEKAREQQQQMAELHGKLQSSEAEVRGKCEELRGLHGQLDEARAQNSQLTERIRSIEALLEASQAQDAQASRVEADQQQARLMELESQVWCLEKEATELREAVEQQKAKNNDLREKNWKAMEALASAEKSCEEKLRSLTQAKEESEKQLSLTEAQTKEALLALLPGLPTSTNQSYAEWLQELKENACLELSKRPQASPEPSDLAAKLREAEETQSGLQAECDQYRSILAETEAMLKALQKSVEEEEQVWKARVSAAEEELQESRVTVKHLEEVVEKLKGELESSDQVREHTWRLEAELEKHVAAASAECQSYAQEVAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQLSEMKSHVEDGDVAEAPRAEQDPAELKTQLERTEALLGDEQTRRQKLTAEFEEAQLVASQLQAELEKLRCTSALGSSEVEEAAQLKERLEKEKKLTGDLGRAATKLQELLKTTQEQLAKEKDTVQKLQERLDRPEDGSSKEGTSV", "length": 1531, "header": "tr|A0AAA9S0L7-1|A0AAA9S0L7_BOVIN Computationally mapped isoform of Ribosome-binding protein 1 OS=Bos taurus OX=9913 GN=RRBP1 PE=1 SV=1 CANONICAL=F1MDC1-1" }, "locus": { "chromosome": "13", "start_pos": 38011390, "end_pos": 37984817, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000088984.1", "url": "https://www.ensembl.org/id/ENSBTAT00000088984.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077178.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077178.1" } ] } }, { "isoform_ac": "A0AAA9S5D2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5D2/entry", "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTNHQKVEKKKKEKTVEKKGKTKKKEEKPNGKIPDHEPTPGVTILPKDPVWAPAVAVAPTSVQSPVVTAPVATVSAMPQEKLASSPKDKKKKEKKVAKVEPAVSSVVNSIQVLASKAAILEAAPKEVPMVVVSPVGAKGSAPATSSTQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKSEGAQNQGKKSEGAQNQGKKAEGAQNQGKKVEGAQNQGKKAEGAQNQGKKAEGAQNQGKKSEGAQNQGKKGEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKSEGAQNQGKKAEGTPNQGKKAEGAQNQGKKVEGAQNQGKKAEGNQNQGKKSEGTPNQGKKAEGGQNQGKKSEGAQNQGRKAEGAQNQGKKAEGAQNQGKKAEGNQNQGKKAEGNQNQGRKEQSTLDQGKMVEVVQNQSKKADGTPNQGKKAEGAQNQGRKAEGTPNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGRKVEAGQNQGKKADSVANQGTKVEGIANQGKKADGTPNQGKKAEGTSNQGKKSEGSPNQGKKVDASANQGKKAESAPTQGKNADMVQSQEAPKQEAPAKKKSGSKKKGEPGPPDANGTLHLPYKTLVSAVGSMVLSEGEAQRLMEILADKAGIVQDTWHKATQKGDPVVILKRQLEEKEKLLATEQEDAAVAKSKLRELNKELAAEKAKAAAGEAKVKKQLVAREQEITAVQARMQASYREHVKEVQQLQGKIRTLQEQLENGPSAQLARLQQENSILRDALNQATSQVESKQNTELAKLRQELGKVSKELVEKSEAVRQEEQQRKALEAKAAAVEKQVLQLQASHKESEEALQKRLDEVSRELCRAQSSHASLRADAEKAREQQQQMAELHGKLQSSEAEVRGKCEELRGLHGQLDEARAQNSQLTERIRSIEALLEASQAQDAQASRVEADQQQARLMELESQVWCLEKEATELREAVEQQKAKNNDLREKNWKAMEALASAEKSCEEKLRSLTQAKEESEKQLSLTEAQTKEALLALLPGLPTSTNQSYAEWLQELKENACLELSKRPQASPEPSDLAAKLREAEETQSGLQAECDQYRSILAETEAMLKALQKSVEEEEQVWKARVSAAEEELQESRVTVKHLEEVVEKLKGELESSDQVREHTWRLEAELEKHVAAASAECQSYAQEVAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQLSEMKSHVEDGDVAEAPRAEQDPAELKTQLERTEALLGDEQTRRQKLTAEFEEAQLVASQLQAELEKLRCTSALGSSEVEEAAQLKERLEKEKKLTGDLGRAATKLQELLKTTQEQLAKEKDTVQKLQERLDRPEDGSSKEGTSV", "length": 1491, "header": "tr|A0AAA9S5D2-1|A0AAA9S5D2_BOVIN Computationally mapped isoform of Ribosome-binding protein 1 OS=Bos taurus OX=9913 GN=RRBP1 PE=1 SV=1 CANONICAL=F1MDC1-1" }, "locus": { "chromosome": "13", "start_pos": 38011390, "end_pos": 37984817, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109356.1", "url": "https://www.ensembl.org/id/ENSBTAT00000109356.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080397.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080397.1" } ] } }, { "isoform_ac": "A0AAA9SF38-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SF38/entry", "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTNHQKVEKKKKEKTVEKKGKTKKKEEKPNGKIPDHEPTPGVTILPKDPVWAPAVAVAPTSVQSPVVTAPVATVSAMPQEKLASSPKDKKKKEKKVAKVEPAVSSVVNSIQVLASKAAILEAAPKEVPMVVVSPVGAKGSAPATSSTQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKSEGAQNQGKKSEGAQNQGKKAEGAQNQGKKVEGAQNQGKKAEGAQNQGKKVEGAQNQGKKAEGAQNQGKKSEGAQNQGKKGEGAQNQGKKAEGAQNQGKKSEGAQNQGKKSEGTPNQSKKVEGAQNQGKKTEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKSEGAQNQGKKAEGTPNQGKKAEGAQNQGKKVEGAQNQGKKAEGNQNQGKKSEGTPNQGKKAEGGQNQGKKSEGAQNQGRKAEGAQNQGKKAEGAQNQGKKAEGNQNQGKKAEGNQNQGRKEQSTLDQGKMVEVVQNQSKKADGTPNQGKKAEGAQNQGRKAEGTPNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGRKVEAGQNQGKKADSVANQGTKVEGIANQGKKADGTPNQGKKAEGTSNQGKKSEGSPNQGKKVDASANQGKKAESAPTQGKNADMVQSQEAPKQEAPAKKKSGSKKKGEPGPPDANGTLHLPYKTLVSAVGSMVLSEGEAQRLMEILADKAGIVQDTWHKATQKGDPVVILKRQLEEKEKLLATEQEDAAVAKSKLRELNKELAAEKAKAAAGEAKVKKQLVAREQEITAVQARMQASYREHVKEVQQLQGKIRTLQEQLENGPSAQLARLQQENSILRDALNQATSQVESKQNTELAKLRQELGKVSKELVEKSEAVRQEEQQRKALEAKAAAVEKQVLQLQASHKESEEALQKRLDEVSRELCRAQSSHASLRADAEKAREQQQQMAELHGKLQSSEAEVRGKCEELRGLHGQLDEARAQNSQLTERIRSIEALLEASQAQDAQASRVEADQQQARLMELESQVWCLEKEATELREAVEQQKAKNNDLREKNWKAMEALASAEKSCEEKLRSLTQAKEESEKQLSLTEAQTKEALLALLPGLPTSTNQSYAEWLQELKENACLELSKRPQASPEPSDLAAKLREAEETQSGLQAECDQYRSILAETEAMLKALQKSVEEEEQVWKARVSAAEEELQESRVTVKHLEEVVEKLKGELESSDQVREHTWRLEAELEKHVAAASAECQSYAQEVAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQLSEMKSHVEDGDVAEAPRAEQDPAELKTQLERTEALLGDEQTRRQKLTAEFEEAQLVASQLQAELEKLRCTSALGSSEVEEAAQLKERLEKEKKLTGDLGRAATKLQELLKTTQEQLAKEKDTVQKLQERLDRPEDGSSKEGTSV", "length": 1541, "header": "tr|A0AAA9SF38-1|A0AAA9SF38_BOVIN Computationally mapped isoform of Ribosome-binding protein 1 OS=Bos taurus OX=9913 GN=RRBP1 PE=1 SV=2 CANONICAL=F1MDC1-1" }, "locus": { "chromosome": "13", "start_pos": 38011390, "end_pos": 37984817, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000122852.2", "url": "https://www.ensembl.org/id/ENSBTAT00000122852.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081054.2", "url": "https://www.ensembl.org/id/ENSBTAP00000081054.2" } ] } }, { "isoform_ac": "A0AAA9SIW4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIW4/entry", "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTNHQKVEKKKKEKTVEKKGKTKKKEEKPNGKIPDHEPTPGVTILPKDPVWAPAVAVAPTSVQSPVVTAPVATVSAMPQEKLASSPKDKKKKEKKVAKVEPAVSSVVNSIQVLASKAAILEAAPKEVPMVVVSPVGAKGSAPATSSTQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKSEGAQNQGKKSEGAQNQGKKAEGAQNQGKKVEGAQNQGKKAEGAQNQGKKSEGAQNQGKKGEGAQNQGKKAEGAQNQGKKSEGAQNQGKKSEGTPNQSKKVEGAQNQGKKTEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKSEGAQNQGKKAEGTPNQGKKAEGAQNQGKKVEGAQNQGKKAEGNQNQGKKSEGTPNQGKKAEGGQNQGKKSEGAQNQGRKAEGAQNQGKKAEGAQNQGKKAEGNQNQGKKAEGNQNQGRKEQSTLDQGKMVEVVQNQSKKADGTPNQGKKAEGAQNQGRKAEGTPNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGRKVEAGQNQGKKADSVANQGTKVEGIANQGKKADGTPNQGKKAEGTSNQGKKSEGSPNQGKKVDASANQGKKAESAPTQGKNADMVQSQEAPKQEAPAKKKSGSKKKGEPGPPDANGTLHLPYKTLVSAVGSMVLSEGEAQRLMEILADKAGIVQDTWHKATQKGDPVVILKRQLEEKEKLLATEQEDAAVAKSKLRELNKELAAEKAKAAAGEAKVKKQLVAREQEITAVQARMQASYREHVKEVQQLQGKIRTLQEQLENGPSAQLARLQQENSILRDALNQATSQVESKQNTELAKLRQELGKVSKELVEKSEAVRQEEQQRKALEAKAAAVEKQVLQLQASHKESEEALQKRLDEVSRELCRAQSSHASLRADAEKAREQQQQMAELHGKLQSSEAEVRGKCEELRGLHGQLDEARAQNSQLTERIRSIEALLEASQAQDAQASRVEADQQQARLMELESQVWCLEKEATELREAVEQQKAKNNDLREKNWKAMEALASAEKSCEEKLRSLTQAKEESEKQLSLTEAQTKEALLALLPGLPTSTNQSYAEWLQELKENACLELSKRPQASPEPSDLAAKLREAEETQSGLQAECDQYRSILAETEAMLKALQKSVEEEEQVWKARVSAAEEELQESRVTVKHLEEVVEKLKGELESSDQVREHTWRLEAELEKHVAAASAECQSYAQEVAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQLSEMKSHVEDGDVAEAPRAEQDPAELKTQLERTEALLGDEQTRRQKLTAEFEEAQLVASQLQAELEKLRCTSALGSSEVEEAAQLKERLEKEKKLTGDLGRAATKLQELLKTTQEQLAKEKDTVQKLQERLDRPEDGSSKEGTSV", "length": 1511, "header": "tr|A0AAA9SIW4-1|A0AAA9SIW4_BOVIN Computationally mapped isoform of Ribosome-binding protein 1 OS=Bos taurus OX=9913 GN=RRBP1 PE=1 SV=2 CANONICAL=F1MDC1-1" }, "locus": { "chromosome": "13", "start_pos": 38011390, "end_pos": 37984817, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000092636.2", "url": "https://www.ensembl.org/id/ENSBTAT00000092636.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083733.2", "url": "https://www.ensembl.org/id/ENSBTAP00000083733.2" } ] } }, { "isoform_ac": "A0AAA9SRN3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SRN3/entry", "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTNHQKVEKKKKEKTVEKKGKTKKKEEKPNGKIPDHEPTPGVTILPKDPVWAPAVAVAPTSVQSPVVTAPVATVSAMPQEKLASSPKDKKKKEKKVAKVEPAVSSVVNSIQVLASKAAILEAAPKEVPMVVVSPVGAKGSAPATSSTQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKSEGAQNQGKKSEGAQNQGKKAEGAQNQGKKVEGAQNQGKKAEGAQNQGKKVEGAQNQGKKAEGAQNQGKKSEGAQNQGKKGEGAQNQGKKAEGAQNQGKKSEGAQNQGKKSEGTPNQSKKVEGAQNQGKKTEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKSEGAQNQGKKAEGTPNQGKKAEGAQNQGKKVEGAQNQGKKAEGNQNQGKKSEGTPNQGKKAEGGQNQGKKSEGAQNQGRKAEGAQNQGKKAEGAQNQGKKAEGNQNQGKKAEGNQNQGRKEQSTLDQGKMVEVVQNQSKKADGTPNQGKKAEGAQNQGRKAEGTPNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGRKVEAGQNQGKKADSVANQGTKVEGIANQGKKADGTPNQGKKAEGTSNQGKKSEGSPNQGKKVDASANQGKKAESAPTQGKNADMVQSQEAPKQEAPAKKKSGSKKKGEPGPPDANGTLHLPYKTLVSAVGSMVLSEGEAQRLMEILADKAGIVQDTWHKATQKGDPVVILKRQLEEKEKLLATEQEDAAVAKSKLRELNKELAAEKAKAAAGEAKVKKQLVAREQEITAVQARMQASYREHVKEVQQLQGKIRTLQEQLENGPSAQLARLQQENSILRDALNQATSQVESKQNTELAKLRQELGKVSKELVEKSEAVRQEEQQRKALEAKAAAVEKQVLQLQASHKESEEALQKRLDEVSRELCRAQSSHASLRADAEKAREQQQQMAELHGKLQSSEAEVRGKCEELRGLHGQLDEARAQNSQLTERIRSIEALLEASQAQDAQASRVEADQQQARLMELESQVWCLEKEATELREAVEQQKAKNNDLREKNWKAMEALASAEKSCEEKLRSLTQAKEESEKQLSLTEAQTKEALLALLPGLPTSTNQSYAEWLQELKENACLELSKRPQASPEPSDLAAKLREAEETQSGLQAECDQYRSILAETEAMLKALQKSVEEEEQVWKARVSAAEEELQESRVTVKHLEEVVEKLKGELESSDQVREHTWRLEAELEKHVAAASAECQSYAQEVAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQLSEMKSHVEDGDVAEAPRAEQDPAELKTQLERTEALLGDEQTRRQKLTAEFEEAQLVASQLQAELEKLRCTSALGSSEVEEAAQLKERLEKEKKLTGDLGRAATKLQELLKTTQEQLAKEKDTVQKLQERLDRPEDGSSKEGTSV", "length": 1531, "header": "tr|A0AAA9SRN3-1|A0AAA9SRN3_BOVIN Computationally mapped isoform of Ribosome-binding protein 1 OS=Bos taurus OX=9913 GN=RRBP1 PE=1 SV=2 CANONICAL=F1MDC1-1" }, "locus": { "chromosome": "13", "start_pos": 38011390, "end_pos": 37984817, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118215.2", "url": "https://www.ensembl.org/id/ENSBTAT00000118215.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085634.2", "url": "https://www.ensembl.org/id/ENSBTAP00000085634.2" } ] } }, { "isoform_ac": "A0AAA9TMZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMZ4/entry", "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTNHQKVEKKKKEKTVEKKGKTKKKEEKPNGKIPDHEPTPGVTILPKDPVWAPAVAVAPTSVQSPVVTAPVATVSAMPQEKLASSPKDKKKKEKKVAKVEPAVSSVVNSIQVLASKAAILEAAPKEVPMVVVSPVGAKGSAPATSSTQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKSEGAQNQGKKSEGAQNQGKKAEGAQNQGKKVEGAQNQGKKAEGAQNQGKKVEGAQNQGKKAEGAQNQGKKSEGAQNQGKKGEGAQNQGKKAEGAQNQGKKSEGTPNQSKKVEGAQNQGKKTEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKSEGAQNQGKKAEGTPNQGKKAEGAQNQGKKVEGAQNQGKKAEGNQNQGKKSEGTPNQGKKAEGGQNQGKKSEGAQNQGRKAEGAQNQGKKAEGAQNQGKKAEGNQNQGKKAEGNQNQGRKEQSTLDQGKMVEVVQNQSKKADGTPNQGKKAEGAQNQGRKAEGTPNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGRKVEAGQNQGKKADSVANQGTKVEGIANQGKKADGTPNQGKKAEGTSNQGKKSEGSPNQGKKVDASANQGKKAESAPTQGKNADMVQSQEAPKQEAPAKKKSGSKKKGEPGPPDANGTLHLPYKTLVSAVGSMVLSEGEAQRLMEILADKAGIVQDTWHKATQKGDPVVILKRQLEEKEKLLATEQEDAAVAKSKLRELNKELAAEKAKAAAGEAKVKKQLVAREQEITAVQARMQASYREHVKEVQQLQGKIRTLQEQLENGPSAQLARLQQENSILRDALNQATSQVESKQNTELAKLRQELGKVSKELVEKSEAVRQEEQQRKALEAKAAAVEKQVLQLQASHKESEEALQKRLDEVSRELCRAQSSHASLRADAEKAREQQQQMAELHGKLQSSEAEVRGKCEELRGLHGQLDEARAQNSQLTERIRSIEALLEASQAQDAQASRVEADQQQARLMELESQVWCLEKEATELREAVEQQKAKNNDLREKNWKAMEALASAEKSCEEKLRSLTQAKEESEKQLSLTEAQTKEALLALLPGLPTSTNQSYAEWLQELKENACLELSKRPQASPEPSDLAAKLREAEETQSGLQAECDQYRSILAETEAMLKALQKSVEEEEQVWKARVSAAEEELQESRVTVKHLEEVVEKLKGELESSDQVREHTWRLEAELEKHVAAASAECQSYAQEVAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQLSEMKSHVEDGDVAEAPRAEQDPAELKTQLERTEALLGDEQTRRQKLTAEFEEAQLVASQLQAELEKLRCTSALGSSEVEEAAQLKERLEKEKKLTGDLGRAATKLQELLKTTQEQLAKEKDTVQKLQERLDRPEDGSSKEGTSV", "length": 1541, "header": "tr|A0AAA9TMZ4-1|A0AAA9TMZ4_BOVIN Computationally mapped isoform of Ribosome-binding protein 1 OS=Bos taurus OX=9913 GN=RRBP1 PE=1 SV=1 CANONICAL=F1MDC1-1" }, "locus": { "chromosome": "13", "start_pos": 38011390, "end_pos": 37984817, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109246.1", "url": "https://www.ensembl.org/id/ENSBTAT00000109246.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098622.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098622.1" } ] } }, { "isoform_ac": "A0AAA9U0D2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0D2/entry", "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTNHQKVEKKKKEKTVEKKGKTKKKEEKPNGKIPDHEPTPGVTILPKDPVWAPAVAVAPTSVQSPVVTAPVATVSAMPQEKLASSPKDKKKKEKKVAKVEPAVSSVVNSIQVLASKAAILEAAPKEVPMVVVSPVGAKGSAPATSSTQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKSEGAQNQGKKSEGAQNQGKKAEGAQNQGKKVEGAQNQGKKAEGAQNQGKKSEGAQNQGKKGEGAQNQGKKAEGAQNQGKKSEGAQNQGKKAEGTPNQGKKAEGAQNQGKKAEGNQNQGKKSEGTPNQGKKAEGGQNQGKKSEGAQNQGRKAEGAQNQGKKAEGAQNQGKKAEGNQNQGKKAEGNQNQGRKEQSTLDQGKMVEVVQNQSKKADGTPNQGKKAEGAQNQGRKAEGTPNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGRKVEAGQNQGKKADSVANQGTKVEGIANQGKKADGTPNQGKKAEGTSNQGKKSEGSPNQGKKVDASANQGKKAESAPTQGKNADMVQSQEAPKQEAPAKKKSGSKKKGEPGPPDANGTLHLPYKTLVSAVGSMVLSEGEAQRLMEILADKAGIVQDTWHKATQKGDPVVILKRQLEEKEKLLATEQEDAAVAKSKLRELNKELAAEKAKAAAGEAKVKKQLVAREQEITAVQARMQASYREHVKEVQQLQGKIRTLQEQLENGPSAQLARLQQENSILRDALNQATSQVESKQNTELAKLRQELGKVSKELVEKSEAVRQEEQQRKALEAKAAAVEKQVLQLQASHKESEEALQKRLDEVSRELCRAQSSHASLRADAEKAREQQQQMAELHGKLQSSEAEVRGKCEELRGLHGQLDEARAQNSQLTERIRSIEALLEASQAQDAQASRVEADQQQARLMELESQVWCLEKEATELREAVEQQKAKNNDLREKNWKAMEALASAEKSCEEKLRSLTQAKEESEKQLSLTEAQTKEALLALLPGLPTSTNQSYAEWLQELKENACLELSKRPQASPEPSDLAAKLREAEETQSGLQAECDQYRSILAETEAMLKALQKSVEEEEQVWKARVSAAEEELQESRVTVKHLEEVVEKLKGELESSDQVREHTWRLEAELEKHVAAASAECQSYAQEVAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQLSEMKSHVEDGDVAEAPRAEQDPAELKTQLERTEALLGDEQTRRQKLTAEFEEAQLVASQLQAELEKLRCTSALGSSEVEEAAQLKERLEKEKKLTGDLGRAATKLQELLKTTQEQLAKEKDTVQKLQERLDRPEDGSSKEGTSV", "length": 1441, "header": "tr|A0AAA9U0D2-1|A0AAA9U0D2_BOVIN Computationally mapped isoform of Ribosome-binding protein 1 OS=Bos taurus OX=9913 GN=RRBP1 PE=1 SV=2 CANONICAL=F1MDC1-1" }, "locus": { "chromosome": "13", "start_pos": 38011390, "end_pos": 37984817, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102135.2", "url": "https://www.ensembl.org/id/ENSBTAT00000102135.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103365.2", "url": "https://www.ensembl.org/id/ENSBTAP00000103365.2" } ] } }, { "isoform_ac": "F1MDC1-1", "url": "https://www.uniprot.org/uniprotkb/F1MDC1/entry", "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTNHQKVEKKKKEKTVEKKGKTKKKEEKPNGKIPDHEPTPGVTILPKDPVWAPAVAVAPTSVQSPVVTAPVATVSAMPQEKLASSPKDKKKKEKKVAKVEPAVSSVVNSIQVLASKAAILEAAPKEVPMVVVSPVGAKGSAPATSSTQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKSEGAQNQGKKSEGAQNQGKKAEGAQNQGKKVEGAQNQGKKAEGAQNQGKKVEGAQNQGKKAEGAQNQGKKSEGAQNQGKKGEGAQNQGKKAEGAQNQGKKSEGAQNQGKKSEGTPNQSKKVEGAQNQGKKTEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKSEGAQNQGKKAEGTPNQGKKAEGAQNQGKKVEGAQNQGKKAEGNQNQGKKSEGTPNQGKKAEGGQNQGKKSEGAQNQGRKAEGAQNQGKKAEGAQNQGKKAEGNQNQGKKAEGNQNQGRKEQSTLDQGKMVEVVQNQSKKADGTPNQGKKAEGAQNQGRKAEGTPNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGRKVEAGQNQGKKADSVANQGTKVEGIANQGKKADGTPNQGKKAEGTSNQGKKSEGSPNQGKKVDASANQGKKAESAPTQGKNADMVQSQEAPKQEAPAKKKSGSKKKGEPGPPDANGTLHLPYKTLVSAVGSMVLSEGEAQRLMEILADKAGIVQDTWHKATQKGDPVVILKRQLEEKEKLLATEQEDAAVAKSKLRELNKELAAEKAKAAAGEAKVKKQLVAREQEITAVQARMQASYREHVKEVQQLQGKIRTLQEQLENGPSAQLARLQQENSILRDALNQATSQVESKQNTELAKLRQELGKVSKELVEKSEAVRQEEQQRKALEAKAAAVEKQVLQLQASHKESEEALQKRLDEVSRELCRAQSSHASLRADAEKAREQQQQMAELHGKLQSSEAEVRGKCEELRGLHGQLDEARAQNSQLTERIRSIEALLEASQAQDAQASRVEADQQQARLMELESQVWCLEKEATELREAVEQQKAKNNDLREKNWKAMEALASAEKSCEEKLRSLTQAKEESEKQLSLTEAQTKEALLALLPGLPTSTNQSYAEWLQELKENACLELSKRPQASPEPSDLAAKLREAEETQSGLQAECDQYRSILAETEAMLKALQKSVEEEEQVWKARVSAAEEELQESRVTVKHLEEVVEKLKGELESSDQVREHTWRLEAELEKHVAAASAECQSYAQEVAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQLSEMKSHVEDGDVAEAPRAEQDPAELKTQLERTEALLGDEQTRRQKLTAEFEEAQLVASQLQAELEKLRCTSALGSSEVEEAAQLKERLEKEKKLTGDLGRAATKLQELLKTTQEQLAKEKDTVQKLQERLDRPEDGSSKEGTSV", "length": 1551, "header": "tr|F1MDC1-1|F1MDC1_BOVIN Isoform 1 of Ribosome-binding protein 1 OS=Bos taurus OX=9913 GN=RRBP1 PE=1 SV=5 CANONICAL=F1MDC1-1" }, "locus": { "chromosome": "13", "start_pos": 38011390, "end_pos": 37984817, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061585.5", "url": "https://www.ensembl.org/id/ENSBTAT00000061585.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053740.5", "url": "https://www.ensembl.org/id/ENSBTAP00000053740.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 110, "start_aa": "Thr", "end_pos": 110, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr110", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "F1MDC1", "url": "https://www.uniprot.org/uniprotkb/F1MDC1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1MDC1", "url": "https://www.uniprot.org/uniprotkb/F1MDC1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1228, "end_pos": 1230, "annotation": "n_glycosylation_sequon" }, { "start_pos": 417, "end_pos": 419, "annotation": "n_glycosylation_sequon" }, { "start_pos": 617, "end_pos": 619, "annotation": "n_glycosylation_sequon" }, { "start_pos": 795, "end_pos": 797, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1MDC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC1" }, { "id": "PF05104", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05104" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ribosome receptor lysine/proline rich", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 167, "start_aa": "Met", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 110 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1228, "end_pos": 1230 }, { "start_pos": 417, "end_pos": 419 }, { "start_pos": 617, "end_pos": 619 }, { "start_pos": 795, "end_pos": 797 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"type": "synonym", "evidence": [ { "id": "XP_002686765", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002686765" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BQ00", "url": "https://www.uniprot.org/uniprotkb/E1BQ00" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DMTF1", "url": "https://www.uniprot.org/uniprotkb/E1BQ00", "locus": { "chromosome": "4", "start_pos": 33248656, "end_pos": 33298766, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020878", "url": "https://www.ensembl.org/id/ENSBTAG00000020878" } ] } } ], "crossref": [ { "id": "E1BQ00", "url": "https://alphafold.ebi.ac.uk/entry/E1BQ00", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020878", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020878", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00167", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00167", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "539676", "url": "https://www.ncbi.nlm.nih.gov/gene/539676", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051651", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051651", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539676", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539676", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LQCHTPR", "url": "https://omabrowser.org/oma/group/LQCHTPR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LII2", "url": "https://www.orthodb.org/?gene=A0A3Q1LII2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MF07", "url": "https://www.orthodb.org/?gene=A0A3Q1MF07", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MMR2", "url": "https://www.orthodb.org/?gene=A0A3Q1MMR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BQ00", "url": "https://www.orthodb.org/?gene=E1BQ00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46380", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46380", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46380:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46380:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00249", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00249", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20588", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20588", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002686765", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002686765", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LII2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LII2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LII2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LII2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MF07", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MF07-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MMR2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MMR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQ00", "url": "https://www.uniprot.org/uniprotkb/E1BQ00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQ00-1", "url": "https://www.uniprot.org/uniprotkb/E1BQ00-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTVEEDSDTVTVETVDSVTLTRDTDGNLILHCPHNEADEIDSEDSTEPPHKRLCLSSEDDQSIDDSTPCISVVALPLSENDQSFEVTMTATTEVADDEITEGTVTQIQILQNEQLDEISPLGNEEVSAVSQAWFTTKEDKDSLTNKGHKWKQGMWSKEEIDILMNNIERYLKARGIKDATEIIFEMSKDERKDFYRTIAWGLNRPLFAVYRRVLRMYDDRNHVGKYTPEEIEKLKELRIKHGNDWATIGAALGRSASSVKDRCRLMKDTCNTGKWTEEEEKRLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDEINLILRIAELDVADENDINWDLLAEGWSSVRSPQWLRSKWWTIKRQIANHKDVSFPVLIKGLKQLHENQKNNPTLLENKSGPGVPNSNSNSSVQHVQIRVARLEDNGAISPSPMTALQIPVQITHVSSADSAAATVDSETITLNSGTLQTFEILPSFHLQPTGTPGTYLLQTSSSQGLPLTLTASPTVTLAAAAPASPEQIIVHALSPEHLLNTSDVTVQCHAPRVIIQTVATEDIASSISQAELTVDSDIHSSDFPEPPDALEADTFPDEIHQPKITVEPSFNDAHISKFSDQNSTELMNSIMVRTEEEISVTHLKQEDEPSPLARAYVTEDLGSPTIEEQVHQTTIDDETILIVPSPHGFIQTSDVIDTESVLPLTTLTDPILQHHREESNIIGSSLGSPVSEDSKDVEDLVHCH", "length": 761, "header": "tr|E1BQ00-1|E1BQ00_BOVIN Isoform 1 of Cyclin-D-binding Myb-like transcription factor 1 OS=Bos taurus OX=9913 GN=DMTF1 PE=3 SV=1 CANONICAL=E1BQ00-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LII2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LII2/entry", "sequence": { "sequence": "MSTVEEDSDTVTVETVDSVTLTRDTDGNLILHCPHNEADEIDSEDSTEPPHKRLCLSSEDDQSIDDSTPCISVVALPLSENDQSFEVTMTATTEVADDEITEGTVTQIQARGIKDATEIIFEMSKDERKDFYRTIAWGLNRPLFAVYRRVLRMYDDRNHVGKYTPEEIEKLKELRIKHGNDWATIGAALGRSASSVKDRCRLMKDTCNTGKWTEEEEKRLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDEINLILRIAELDVADENDINWDLLAEGWSSVRSPQWLRSKWWTIKRQIANHKDVSFPVLIKGLKQLHENQKNNPTLLENKSGPGVPNSNSNSSVQHVQIRVARLEDNGAISPSPMTALQIPVQITHVSSADSAAATVDSETITLNSGTLQTFEILPSFHLQPTGTPGTYLLQTSSSQGLPLTLTASPTVTLAAAAPASPEQIIVHALSPEHLLNTSDVTVQCHAPRVIIQTVATEDIASSISQAELTVDSDIHSSDFPEPPDALEADTFPDEIHQPKITVEPSFNDAHISKFSDQNSTELMNSIMVRTEEEISVTHLKQEDEPSPLARAYVTEDLGSPTIEEQVHQTTIDDETILIVPSPHGFIQTSDVIDTESVLPLTTLTDPILQHHREESNIIGSSLGSPVSEDSKDVEDLVHCH", "length": 697, "header": "tr|A0A3Q1LII2-1|E1BQ00_BOVIN Computationally mapped isoform of Cyclin-D-binding Myb-like transcription factor 1 OS=Bos taurus OX=9913 GN=DMTF1 PE=3 SV=2 CANONICAL=E1BQ00-1" }, "locus": { "chromosome": "4", "start_pos": 33286857, "end_pos": 33249640, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073223.2", "url": "https://www.ensembl.org/id/ENSBTAT00000073223.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058855.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058855.2" } ] } }, { "isoform_ac": "A0A3Q1MF07-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF07/entry", "sequence": { "sequence": "MLLPCLHQQLINLSMSTVEEDSDTVTVETVDSVTLTRDTDGNLILHCPHNEADEIDSEDSTEPPHKRLCLSSEDDQSIDDSTPCISVVALPLSENDQSFEVTMTATTEVADDEITEGTVTQIQILQNEQLDEISPLGNEEVSAVSQAWFTTKEDKDSLTNKGHKWKQGMWSKEEIDILMNNIERYLKARGIKDATEIIFEMSKDERKDFYRTIAWGLNRPLFAVYRRVLRMYDDRNHVGKYTPEEIEKLKELRIKHGNDWATIGAALGRSASSVKDRCRLMKDTCNTGKWTEEEEKRLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDEINLILRIAELDVADENDINWDLLAEGWSSVRSPQWLRSKWWTIKRQIANHKDVSFPVLIKGLKQLHENQKNNPTLLENKSGPGVPNSNSNSSVQHVQIRVARLEDNGAISPSPMTALQIPVQITHVSSADSAAATVDSETITLNSGTLQTFEILPSFHLQPTGTPGTYLLQTSSSQGLPLTLTASPTVTLAAAAPASPEQIIVHALSPEHLLNTSDVTVQCHAPRVIIQTVATEDIASSISQAELTVDSDIHSSDFPEPPDALEADTFPDEIHQPKITVEPSFNDAHISKFSDQNSTELMNSIMVRTEEEISVTHLKQEDEPSPLARAYVTEDLGSPTIEEQVHQTTIDDETILIVPSPHGFIQTSDVIDTESVLPLTTLTDPILQHHREESNIIGSSLGSPVSEDSKDVEDLVHCH", "length": 775, "header": "tr|A0A3Q1MF07-1|A0A3Q1MF07_BOVIN Computationally mapped isoform of Cyclin-D-binding Myb-like transcription factor 1 OS=Bos taurus OX=9913 GN=DMTF1 PE=3 SV=2 CANONICAL=E1BQ00-1" }, "locus": { "chromosome": "4", "start_pos": 33296608, "end_pos": 33249640, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086376.2", "url": "https://www.ensembl.org/id/ENSBTAT00000086376.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072757.2", "url": "https://www.ensembl.org/id/ENSBTAP00000072757.2" } ] } }, { "isoform_ac": "A0A3Q1MMR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMR2/entry", "sequence": { "sequence": "MLLPCLHQQLINLSMSTVEEDSDTVTVETVDSVTLTRDTDGNLILHCPHNEADEIDSEDSTEPPHKRLCLSSEDDQSIDDSTPCISVVALPLSENDQSFEVTMTATTEVADDEITEGTVTQIQILQNEQLDEISPLGNEEVSAVSQAWFTTKEDKDSLTNKGHKWKQGMWSKEEIDILMNNIERYLKARGIKDATEIIFEMSKDERKDFYRTIAWGLNRPLFAVYRRVLRMYDDRNHVGKYTPEEIEKLKELRIKHGNDWATIGAALGRSASSVKDRCRLMKDTCNTGKWTEEEEKRLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDEINLILRIAELDVADENDINWDLLAEGWSSVRSPQWLRSKWWTIKRQIANHKDVSFPASADSAAATVDSETITLNSGTLQTFEILPSFHLQPTGTPGTYLLQTSSSQGLPLTLTASPTVTLAAAAPASPEQIIVHALSPEHLLNTSDVTVQCHAPRVIIQTVATEDIASSISQAELTVDSDIHSSDFPEPPDALEADTFPDEIHQPKITVEPSFNDAHISKFSDQNSTELMNSIMVRTEEEISVTHLKQEDEPSPLARAYVTEDLGSPTIEEQVHQTTIDDETILIVPSPHGFIQTSDVIDTESVLPLTTLTDPILQHHREESNIIGSSLGSPVSEDSKDVEDLVHCH", "length": 705, "header": "tr|A0A3Q1MMR2-1|A0A3Q1MMR2_BOVIN Computationally mapped isoform of Cyclin-D-binding Myb-like transcription factor 1 OS=Bos taurus OX=9913 GN=DMTF1 PE=3 SV=2 CANONICAL=E1BQ00-1" }, "locus": { "chromosome": "4", "start_pos": 33296608, "end_pos": 33249640, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082140.2", "url": "https://www.ensembl.org/id/ENSBTAT00000082140.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072466.2", "url": "https://www.ensembl.org/id/ENSBTAP00000072466.2" } ] } }, { "isoform_ac": "E1BQ00-1", "url": "https://www.uniprot.org/uniprotkb/E1BQ00/entry", "sequence": { "sequence": "MSTVEEDSDTVTVETVDSVTLTRDTDGNLILHCPHNEADEIDSEDSTEPPHKRLCLSSEDDQSIDDSTPCISVVALPLSENDQSFEVTMTATTEVADDEITEGTVTQIQILQNEQLDEISPLGNEEVSAVSQAWFTTKEDKDSLTNKGHKWKQGMWSKEEIDILMNNIERYLKARGIKDATEIIFEMSKDERKDFYRTIAWGLNRPLFAVYRRVLRMYDDRNHVGKYTPEEIEKLKELRIKHGNDWATIGAALGRSASSVKDRCRLMKDTCNTGKWTEEEEKRLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDEINLILRIAELDVADENDINWDLLAEGWSSVRSPQWLRSKWWTIKRQIANHKDVSFPVLIKGLKQLHENQKNNPTLLENKSGPGVPNSNSNSSVQHVQIRVARLEDNGAISPSPMTALQIPVQITHVSSADSAAATVDSETITLNSGTLQTFEILPSFHLQPTGTPGTYLLQTSSSQGLPLTLTASPTVTLAAAAPASPEQIIVHALSPEHLLNTSDVTVQCHAPRVIIQTVATEDIASSISQAELTVDSDIHSSDFPEPPDALEADTFPDEIHQPKITVEPSFNDAHISKFSDQNSTELMNSIMVRTEEEISVTHLKQEDEPSPLARAYVTEDLGSPTIEEQVHQTTIDDETILIVPSPHGFIQTSDVIDTESVLPLTTLTDPILQHHREESNIIGSSLGSPVSEDSKDVEDLVHCH", "length": 761, "header": "tr|E1BQ00-1|E1BQ00_BOVIN Isoform 1 of Cyclin-D-binding Myb-like transcription factor 1 OS=Bos taurus OX=9913 GN=DMTF1 PE=3 SV=1 CANONICAL=E1BQ00-1" }, "locus": { "chromosome": "4", "start_pos": 33286857, "end_pos": 33249640, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000033813.5", "url": "https://www.ensembl.org/id/ENSBTAT00000033813.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000033722.3", "url": "https://www.ensembl.org/id/ENSBTAP00000033722.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 508, "start_aa": "Thr", "end_pos": 508, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr508", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:539676", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539676", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5NYR7-1", "protein_name": "Cyclin-D-binding Myb-like transcription factor 1", "gene_name": "DMTF1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSTVEEESDTVTVETVNSVTLTQDTEGNLILHCPQNETDEVNSEDSTEPPHKRLCLSEDDQSLDDSAPCISVVAVPISENDQSFEVTMTATAEVAEDEINEGTVTQIQILQNEQLDEISPMGNEEVSAVSQAWFTTKEDKDSLTNKGHKWKQGMWSKEEIDILMSNIERYLKARGIKDATEIIFEMSKDERKDFYRTIAWGLNRPLFAVYRRVLRMYDDRNHVGKYTPEEIERLKELRIKHGNDWATIGAALGRSASSVKDRCRLMKDTCNTGKWTEEEEKRLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDEINLILRIAELEVSDENDINWDLLAEGWSSVRSPQWLRSKWWTIKRQIANHKDVSFPVLIKGLKQLHENQKNNPGHQLSENKSGGGLPNSNSSSGVQHVQIRVARLEENAGNTPGPVTALQIPVQITHVSSTDSPAATVDSETITLNSGTLQTFEILPSFHLQPTGTPGTYLLQTSSSQGLPLTLTTSPTMTLTAAAAPASPEQIIVHALSPEHLLNTSDNVTVQCHTPSVIIRTVAAEDISSSVTQAELTVDSDIQAADLTDPPDALETNSFPDDIHQSKLSDEEHSAYNEDDASKFSSRNSSELMDGVMVRTEEEISDASLKQEEDSHSDLPSTYVTEDLGSPTIEEQVDQPTIDDETVLIVPSSHGFIQTSDDIDSESVLPLTTLTDPILQHHGDGSHIIGSSLGSPDSEDSKDVEDLVSCH", "length": 767 }, "evidence": [ { "id": "E1BQ00", "url": "https://omabrowser.org/oma/group/E1BQ00/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A4X1SQ26-1", "protein_name": "Cyclin-D-binding Myb-like transcription factor 1", "gene_name": "DMTF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSTVEEDSDTVTVETVNSVTLTRDTDGNLILHCPQNEADEIDSEDSTEPPHKRLCLSSEDDQSIDDSTPCISVVALPLSENDQSFEVTMTATTEVADDEITEGTVTQIQILQNEQLDEISPLGNEEVSAVSQAWFTTKEDKDSLTNKGHKWKQGMWSKEEIDILMNNIERYLKARGIKDATEIIFEMSKDERKDFYRTIAWGLNRPLFAVYRRVLRMYDDRNHVGKYTPEEIEKLKELRIKHGNDWATIGAALGRSASSVKDRCRLMKDTCNTGKWTEEEEKRLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDEINLILRIAELDVADENDINWDLLAEGWSSVRSPQWLRSKWWTIKRQIANHKDVSFPVLIKGLKQLHENQKNNPTLLENKPGSGVPNSNSSSSVQHVQIRVARLEDNAAISPSPMTALQIPVQITHVSSADSPAATVDSETITLNSGTLQTFEILPSFHLQPTGTPGTYLLQTSSSQGLPLTLTASPTVTLTAAAPASPEQIIVHALSPEHLLNTSDNVTVQCHTPRVIIQTVATEDITSSISQAELTVDSDIHSSDFPEPPDALEADTFPDEIHQPKITVEPSFNDAHISKFSDQNSTELMNSVMVRTEEEISDSDLKQEDAPSPLARAYVTEDLESPTIEEQVDQTTIDDETILIVPSPHGFIQTSDVIDTESVLPLTTLTDPILQHHREESNIIGSSLGSPVSEDSKDVEDLVNCH", "length": 762 }, "evidence": [ { "id": "E1BQ00", "url": "https://omabrowser.org/oma/group/E1BQ00/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3I5J6-1", "protein_name": "Cyclin-D-binding Myb-like transcription factor 1", "gene_name": "Dmtf1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSTVEEDSDTVTVETVNSVTFTQDTDGNLILHCPQNDPDEIDSEDSAEPPHKRLCLSSEDDQSIDDSTPCISVVALPLSENDQSFEVTMTATTEVADDELSEGTVTQIQILQNDQLDEISPLGTEEVSAVSQAWFTTKEDKDSLTNKGHKWKQGMWSKEEIDILMNNIERYLKARGIKDATEIIFEMSKDERKDFYRTIAWGLNRPLFAVYRRVLRMYDDRNHVGKYTPEEIEKLKELRIKHGNDWATIGAALGRSASSVKDRCRLMKDTCNTGKWTEEEEKRLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDEINLILRIAELDVADENDINWDLLAEGWSSVRSPQWLRSKWWTIKRQIANHKDVSFPVLIKGLKQLHENQKNNPVLLENKSGSGVPNSNCNSSVQHVQIRVARLEDNTAISPSPMAALQIPVQITHVSSTDSPAASVDSETITLNSGTLQTFEILPSFHLQPTGTPGTYLLQTSSSQGLPLTLTTSPTVTLAAAAPASPEQIIVHALSPEHLLNTSDNVTVQCHTPRVIIQTVATEDIASSVSQAELTVGSDLHSSDFPEPPDALEADTFPDEIPQPKMTIQPSFNTHVSKFSDQNSTELMNSVMVRTEEEIADTDLKQEEPPADLASAYVTEDLESPTIVHQVHQTIDDETILIVPSPHGFIQASDVIDTESVLPLTTLTDPIFQHHQEESNIIGSSLGSPVSEDSKDVEDLVNCH", "length": 760 }, "evidence": [ { "id": "E1BQ00", "url": "https://omabrowser.org/oma/group/E1BQ00/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q66HG1-1", "protein_name": "Cyclin-D-binding Myb-like transcription factor 1", "gene_name": "Dmtf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSTVEEDSDTVTVETVNSVTFTQDTDGNLILHCPQNDPDEIDSEDSTEPPHKRLCLSSEDDQSIDDSTPCISVVALPLSENDQSFEVTMTATTEVADDELSEGTVTQIQILQNDQLDEMSPLGTEEVSAVSQAWFTTKEDKDSLTNKGHKWKQGMWSKEEIDILMNNIERYLKARGIKDATEIIFEMSKDERKDFYRTIAWGLNRPLFAVYRRVLRMYDDRNHVGKYTPEEIEKLKELRIKHGNDWATIGAALGRSASSVKDRCRLMKDTCNTGKWTEEEEKRLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDEINLILRIAELDVADENDINWDLLAEGWSSVRSPQWLRSKWWTIKRQIANHKDVSFPVLIKGLKQLHENQKNNPVLLENKSGSGVPNSNCNSSVQHVQIRVARLEDNTAISPSPMAALQIPVQITHVSSTDSPAASVDSETITLNSGTLQTFEILPSFHLQPTGTPGTYLLQTSSSQGLPLTLTTSPTVTLAAAAPASPEQIIVHALSPEHLLNTSDNVTVQCHTPRVIIQTVATEDITSSISQAELTADSDLHSSDFPEPPDALEADTFPDEIPRPKMTIQPSFNNAHVSKYSDQNSTELMNSVMVRTEEEIADTDLKQEPPSDLASAYVTEDLESPTIVHQVHQTIDDETILIVPSPHGFIQASDGIDAESVLPLTTLTDPIFQHHQEESNIIGSSLGSPVSEDSKDVEDLVNCH", "length": 760 }, "evidence": [ { "id": "E1BQ00", "url": "https://omabrowser.org/oma/group/E1BQ00/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6DG03-1", "protein_name": "Cyclin-D-binding Myb-like transcription factor 1", "gene_name": "dmtf1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNTGDVPATVTLESVNSVTFTQDTDGNIILHCPQNDGEDLGSDETTEPVHKRIRLSSEDGEDPQDSASTEYSVVTLPITDGDESFEVTMTATEMRDEELESDDLSETTGKDSSAQKKGEDVSAVSQAWFTTKEDKDTLVNKGHKWKQGMWSKEEIDLLMTNIELYLKNRGIQDPAEIIFEMSKEERKDFYRSIACGLNRPLFAVYRRVLRMYDNRNHVGKYTDEEINKLKELRQKHGNDWATIGSALGRSASSVKDRCRLMKDTCNTGKWTEEEERRLAEVVHELTGTEAGDVVTQGVSWASVAELVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDDINLVRRIAELEVEDENEINWDILASGWSSVRSPQWLRSKWWTIKRQVANHKELPFPVLLKGLQDVVEAPPSTMNKVVVVGSRSANASPSPVTALQIPVQIPVQITHVSSSDGSSGTSDSETITLNSGALQTFELLPSFHLQPTGTPGTYFLQTGTNQSLPLTLSANPTVTLTAAASPSSPDQIILHSLTTDTENVTVQMSHPGIIIQTVTSEDLADPLGQSELEGEQVLVKEEPSENQTNPAIEEPSEEQSKQGEKTLDSSKVVETVLMVPSPGSFIPTNEDISSDSVLPLGTLTDPILENQEEGSN", "length": 645 }, "evidence": [ { "id": "E1BQ00", "url": "https://omabrowser.org/oma/group/E1BQ00/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8CE22-1", "protein_name": "Cyclin-D-binding Myb-like transcription factor 1", "gene_name": "Dmtf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTVEEDSDTVTVETVNSVTFTQDTDGNLILHCPQNDPDEVDSEDSTEPPHKRLCLSSEDDQSIDDATPCISVVALPLSENDQSFEVTMTATTEVADDELSEGTVTQIQILQNDQLDEISPLGTEEVSAVSQAWFTTKEDKDSLTNKGHKWKQGMWSKEEIDILMNNIERYLKARGIKDATEIIFEMSKDERKDFYRTIAWGLNRPLFAVYRRVLRMYDDRNHVGKYTPEEIEKLKELRIKHGNDWATIGAALGRSASSVKDRCRLMKDTCNTGKWTEEEEKRLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDEINLILRIAELDVADENDINWDLLAEGWSSVRSPQWLRSKWWTIKRQIANHKDVSFPVLIKGLKQLHENQKNNPVLLENKSGSGVPNSNCNSSVQHVQIRVARLEDNTAISPSPMAALQIPVQITHVSSTDSPAASVDSETITLNSGTLQTFEILPSFHLQPTGTPGTYLLQTSSSQGLPLTLTTNPTVTLAAAAPASPEQIIVHALSPEHLLNTSDNVTVQCHTPRVIIQTVATEDITSSLSQEELTVDSDLHSSDFPEPPDALEADTFPDEIPRPKMTIQPSFNNAHVSKFSDQNSTELMNSVMVRTEEEIADTDLKQEEPPSDLASAYVTEDLESPTIVHQVHQTIDDETILIVPSPHGFIQASDVIDTESVLPLTTLTDPIFQHHQEASNIIGSSLGSPVSEDSKDVEDLVNCH", "length": 761 }, "evidence": [ { "id": "E1BQ00", "url": "https://omabrowser.org/oma/group/E1BQ00/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y222-1", "protein_name": "Cyclin-D-binding Myb-like transcription factor 1", "gene_name": "DMTF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSTVEEDSDTVTVETVNSVTLTQDTEGNLILHCPQNEADEIDSEDSIEPPHKRLCLSSEDDQSIDDSTPCISVVALPLSENDQSFEVTMTATTEVADDEVTEGTVTQIQILQNEQLDEISPLGNEEVSAVSQAWFTTKEDKDSLTNKGHKWKQGMWSKEEIDILMNNIERYLKARGIKDATEIIFEMSKDERKDFYRTIAWGLNRPLFAVYRRVLRMYDDRNHVGKYTPEEIEKLKELRIKHGNDWATIGAALGRSASSVKDRCRLMKDTCNTGKWTEEEEKRLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDEINLILRIAELDVADENDINWDLLAEGWSSVRSPQWLRSKWWTIKRQIANHKDVSFPVLIKGLKQLHENQKNNPTLLENKSGSGVPNSNTNSSVQHVQIRVARLEDNTAISSSPMAALQIPVQITHVSSADSPATVDSETITLNSGTLQTFEILPSFHLQPTGTPGTYLLQTSSSQGLPLTLTASPTVTLTAAAPASPEQIIVHALSPEHLLNTSDNVTVQCHTPRVIIQTVATEDITSSISQAELTVDSDIQSSDFPEPPDALEADTFPDEIHHPKMTVEPSFNDAHVSKFSDQNSTELMNSVMVRTEEEISDTDLKQEESPSDLASAYVTEGLESPTIEEQVDQTIDDETILIVPSPHGFIQASDVIDTESVLPLTTLTDPILQHHQEESNIIGSSLGSPVSEDSKDVEDLVNCH", "length": 760 }, "evidence": [ { "id": "E1BQ00", "url": "https://omabrowser.org/oma/group/E1BQ00/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BQ00", "url": "https://www.uniprot.org/uniprotkb/E1BQ00" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BQ00", "url": "https://www.uniprot.org/uniprotkb/E1BQ00" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BQ00", "url": "https://www.uniprot.org/uniprotkb/E1BQ00" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BQ00", "url": "https://www.uniprot.org/uniprotkb/E1BQ00" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BQ00", "url": "https://www.uniprot.org/uniprotkb/E1BQ00" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BQ00", "url": "https://www.uniprot.org/uniprotkb/E1BQ00" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BQ00", "url": "https://www.uniprot.org/uniprotkb/E1BQ00" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" }, { "start_pos": 434, "end_pos": 436, "annotation": "n_glycosylation_sequon" }, { "start_pos": 557, "end_pos": 559, "annotation": "n_glycosylation_sequon" }, { "start_pos": 639, "end_pos": 641, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BQ00-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 761, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BQ00-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BQ00" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BQ00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ00" }, { "id": "PS51294", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51294" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HTH myb-type", "eco_id": "ECO_0000259", "start_pos": 268, "end_pos": 333, "start_aa": "Lys", "end_aa": "Gln", "glycosite_overlap": [] }, { "evidence": [ { "id": "E1BQ00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ00" }, { "id": "PS50090", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50090" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myb-like", "eco_id": "ECO_0000259", "start_pos": 268, "end_pos": 329, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 508 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 422, "end_pos": 424 }, { "start_pos": 434, "end_pos": 436 }, { "start_pos": 557, "end_pos": 559 }, { "start_pos": 639, "end_pos": 641 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BMP4-1", "uniprot_ac": "E1BMP4", "uniprot_id": "E1BMP4_BOVIN", "mass": { "chemical_mass": 117415.0, "monoisotopic_mass": 117415.0 }, "refseq": {}, "gene_names": [ { "name": "BICRAL", "type": "recommended", "evidence": [ { "id": "E1BMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP4" } ] } ], "protein_names": [ { "name": "BICRA like chromatin remodeling complex associated protein", "type": "synonym", "evidence": [ { "id": "E1BMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMP4", "url": "https://www.uniprot.org/uniprotkb/E1BMP4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "BICRAL", "url": "https://www.uniprot.org/uniprotkb/E1BMP4", "locus": { "chromosome": "23", "start_pos": 16506078, "end_pos": 16414584, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014814", "url": "https://www.ensembl.org/id/ENSBTAG00000014814" } ] } } ], "crossref": [ { "id": "E1BMP4", "url": "https://alphafold.ebi.ac.uk/entry/E1BMP4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014814", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014814", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR015671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052438", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052438", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BMP4", "url": "https://www.orthodb.org/?gene=E1BMP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15572", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15572", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15572:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15572:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15249", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15249", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9933947", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9933947", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LJI8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LJI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJI8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TF23", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TF23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TF23-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TF23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TZQ6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TZQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U283", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U283", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U283-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U283-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMP4", "url": "https://www.uniprot.org/uniprotkb/E1BMP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMP4-1", "url": "https://www.uniprot.org/uniprotkb/E1BMP4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEFSKQEYWSGVRLPSSAPMLVVMDDDDDSCLLDLIGDPQALNYFLHGPSNKSSNEDLTNAGYSAANSNSIFANSSNADPKSALKAVSSQLGEGPSDGLPLSSSLQFLEDELESSPLPDLSEDQPFDILQKSLQEANITEQTLAEEAYLDASIGSSQQFAQAQLHPSSSASFTQASNVSNYSGQTLQPIGVTHVPVGTSFASNTVGVHHGFMHHVGISVPSQHLSNSSQISGSGQIQLIGSFGNQPSMMTINNLDGSQIILKGSGQQAPSNVSGGLLVHRQTPNGNSLFGNSSSSPVAQPVTVPFNSTNFQTSLPVHNIIIQRGLAPNSNKVPVNIQPKPIQMGQQNTYNVNNLGIQQHHVQQGISFASASSPQGSVVGPHMSVNIVNQQNTRKPVTSQSVSSAGGSIVIHSPMGQPHTPQSQFLIPTSLSVSSNSVHHVQTINGQLLQTQPSQLISGQVASEHVMLNRNSSNMLRTNQPYSGQMLNNQSAAVQLVSGQTFAASGSPVIVNHASPQIVGGQVPLQQASPTVLHLSPGQSSVSQGRPGFTTMPSVTSMAGPSRFPVSSSSTAHPSLGSAVQSGASGSNFTGDQLTQPNRTPGPVSVSHRLPVPSSKSTSTFSNTPGVGSQQQFFCQAQKKSLNQTSPISASKTTDGLRPAPMPGLLSTALPGQDSGSKVIPASLGTTQPQQEKVVGSPPGQPTVQVDGHPGGQKRPAAKQLTKGAFILQQLQRDQAHAVTPDKNQFRSLSDAVQRLLSYHVCQGSMPTEEDLRKVDSEFETVATQLLKRTQAMLNKYRCLLLEDAMRINPSAEMVMIDRMFNQEERASLSRDKRLALVDPEGFQADFCCSFKLDKAAHEMQFSRSDQHGGKTTSSVHLTAKAQSRDRAKAGLAEPMNHDQFHLVPNHIVVSAEGNISKKTDCLGRALKFDKVGSAQYRSASEEKTSRRDSAKGSECSPGPEGHRKNSSRPDHGPDSKLSSLLVDSQLEMTCNSSFQDKTLRNSPKNEVLHTDIMKGSGEPQPDLQLTKSLETTFKNILELKKAGRQSQSDPTVSGSVELDFPNFSPMASQENCLEKFIPDHSEGVVETDSILEAAVNSILEC", "length": 1101, "header": "tr|E1BMP4-1|E1BMP4_BOVIN Isoform 1 of BICRA like chromatin remodeling complex associated protein OS=Bos taurus OX=9913 GN=BICRAL PE=4 SV=2 CANONICAL=E1BMP4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LJI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJI8/entry", "sequence": { "sequence": "MQKRKNFSVVMDDDDDSCLLDLIGDPQALNYFLHGPSNKSSNEDLTNAGYSAANSNSIFANSSNADPKSALKAVSSQLGEGPSDGLPLSSSLQFLEDELESSPLPDLSEDQPFDILQKSLQEANITEQTLAEEAYLDASIGSSQQFAQAQLHPSSSASFTQASNVSNYSGQTLQPIGVTHVPVGTSFASNTVGVHHGFMHHVGISVPSQHLSNSSQISGSGQIQLIGSFGNQPSMMTINNLDGSQIILKGSGQQAPSNVSGGLLVHRQTPNGNSLFGNSSSSPVAQPVTVPFNSTNFQTSLPVHNIIIQRGLAPNSNKVPVNIQPKPIQMGQQNTYNVNNLGIQQHHVQQGISFASASSPQGSVVGPHMSVNIVNQQNTRKPVTSQSVSSAGGSIVIHSPMGQPHTPQSQFLIPTSLSVSSNSVHHVQTINGQLLQTQPSQLISGQVASEHVMLNRNSSNMLRTNQPYSGQMLNNQSAAVQLVSGQTFAASGSPVIVNHASPQIVGGQVPLQQASPTVLHLSPGQSSVSQGRPGFTTMPSVTSMAGPSRFPVSSSSTAHPSLGSAVQSGASGSNFTGDQLTQPNRTPGPVSVSHRLPVPSSKSTSTFSNTPGVGSQQQFFCQAQKKSLNQTSPISASKTTDGLRPAPMPGLLSTALPGQDSGSKVIPASLGTTQPQQEKVVGSPPGQPTVQVDGHPGGQKRPAAKQLTKGAFILQQLQRDQAHAVTPDKNQFRSLSDAVQRLLSYHVCQGSMPTEEDLRKVDSEFETVATQLLKRTQAMLNKYRCLLLEDAMRINPSAEMVMIDRMFNQEERASLSRDKRLALVDPEGFQADFCCSFKLDKAAHEMQFSRSDQHGGKTTSSVHLTAKAQSRDRAKAGLAEPMNHDQFHLVPNHIVVSAEGNISKKTDCLGRALKFDKVGSAQYRSASEEKTSRRDSAKGSECSPGPEGHRKNSSRPDHGPDSKLSSLLVDSQLEMTCNSSFQDKTLRNSPKNEVLHTDIMKGSGEPQPDLQLTKSLETTFKNILELKKAGRQSQSDPTVSGSVELDFPNFSPMASQENCLEKFIPDHSEGVVETDSILEAAVNSILEC", "length": 1088, "header": "tr|A0A3Q1LJI8-1|E1BMP4_BOVIN Computationally mapped isoform of BICRA like chromatin remodeling complex associated protein OS=Bos taurus OX=9913 GN=BICRAL PE=4 SV=1 CANONICAL=E1BMP4-1" }, "locus": { "chromosome": "23", "start_pos": 16503034, "end_pos": 16456751, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074456.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074456.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056696.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056696.2" } ] } }, { "isoform_ac": "A0AAA9TF23-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TF23/entry", "sequence": { "sequence": "MIPDENLNSIKGLNSTGTVVMDDDDDSCLLDLIGDPQALNYFLHGPSNKSSNEDLTNAGYSAANSNSIFANSSNADPKSALKAVSSQLGEGPSDGLPLSSSLQFLEDELESSPLPDLSEDQPFDILQKSLQEANITEQTLAEEAYLDASIGSSQQFAQAQLHPSSSASFTQASNVSNYSGQTLQPIGVTHVPVGTSFASNTVGVHHGFMHHVGISVPSQHLSNSSQISGSGQIQLIGSFGNQPSMMTINNLDGSQIILKGSGQQAPSNVSGGLLVHRQTPNGNSLFGNSSSSPVAQPVTVPFNSTNFQTSLPVHNIIIQRGLAPNSNKVPVNIQPKPIQMGQQNTYNVNNLGIQQHHVQQGISFASASSPQGSVVGPHMSVNIVNQQNTRKPVTSQSVSSAGGSIVIHSPMGQPHTPQSQFLIPTSLSVSSNSVHHVQTINGQLLQTQPSQLISGQVASEHVMLNRNSSNMLRTNQPYSGQMLNNQSAAVQLVSGQTFAASGSPVIVNHASPQIVGGQVPLQQASPTVLHLSPGQSSVSQGRPGFTTMPSVTSMAGPSRFPVSSSSTAHPSLGSAVQSGASGSNFTGDQLTQPNRTPGPVSVSHRLPVPSSKSTSTFSNTPGVGSQQQFFCQAQKKSLNQTSPISASKTTDGLRPAPMPGLLSTALPGQDSGSKVIPASLGTTQPQQEKVVGSPPGQPTVQVDGHPGGQKRPAAKQLTKGAFILQQLQRDQAHAVTPDKNQFRSLSDAVQRLLSYHVCQGSMPTEEDLRKVDSEFETVATQLLKRTQAMLNKYRCLLLEDAMRINPSAEMVMIDRMFNQEERASLSRDKRLALVDPEGFQADFCCSFKLDKAAHEMQFSRSDQHGGKTTSSVHLTAKAQSRDRAKAGLAEPMNHDQFHLVPNHIVVSAEGNISKKTDCLGRALKFDKVGSAQYRSASEEKTSRRDSAKGSECSPGPEGHRKNSSRPDHGPDSKLSSLLVDSQLEMTCNSSFQDKTLRNSPKNEVLHTDIMKGSGEPQPDLQLTKSLETTFKNILELKKAGRQSQSDPTVSGSVELDFPNFSPMASQENCLEKFIPDHSEGVVETDSILEAAVNSILEC", "length": 1098, "header": "tr|A0AAA9TF23-1|A0AAA9TF23_BOVIN Computationally mapped isoform of BICRA like chromatin remodeling complex associated protein OS=Bos taurus OX=9913 GN=BICRAL PE=4 SV=1 CANONICAL=E1BMP4-1" }, "locus": { "chromosome": "23", "start_pos": 16503034, "end_pos": 16466589, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116658.1", "url": "https://www.ensembl.org/id/ENSBTAT00000116658.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096714.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096714.1" } ] } }, { "isoform_ac": "A0AAA9TZQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZQ6/entry", "sequence": { "sequence": "MSSSNCCFLTCVQISQEAVVMDDDDDSCLLDLIGDPQALNYFLHGPSNKSSNEDLTNAGYSAANSNSIFANSSNADPKSALKAVSSQLGEGPSDGLPLSSSLQFLEDELESSPLPDLSEDQPFDILQKSLQEANITEQTLAEEAYLDASIGSSQQFAQAQLHPSSSASFTQASNVSNYSGQTLQPIGVTHVPVGTSFASNTVGVHHGFMHHVGISVPSQHLSNSSQISGSGQIQLIGSFGNQPSMMTINNLDGSQIILKGSGQQAPSNVSGGLLVHRQTPNGNSLFGNSSSSPVAQPVTVPFNSTNFQTSLPVHNIIIQRGLAPNSNKVPVNIQPKPIQMGQQNTYNVNNLGIQQHHVQQGISFASASSPQGSVVGPHMSVNIVNQQNTRKPVTSQSVSSAGGSIVIHSPMGQPHTPQSQFLIPTSLSVSSNSVHHVQTINGQLLQTQPSQLISGQVASEHVMLNRNSSNMLRTNQPYSGQMLNNQSAAVQLVSGQTFAASGSPVIVNHASPQIVGGQVPLQQASPTVLHLSPGQSSVSQGRPGFTTMPSVTSMAGPSRFPVSSSSTAHPSLGSAVQSGASGSNFTGDQLTQPNRTPGPVSVSHRLPVPSSKSTSTFSNTPGVGSQQQFFCQAQKKSLNQTSPISASKTTDGLRPAPMPGLLSTALPGQDSGSKVIPASLGTTQPQQEKVVGSPPGQPTVQVDGHPGGQKRPAAKQLTKGAFILQQLQRDQAHAVTPDKNQFRSLSDAVQRLLSYHVCQGSMPTEEDLRKVDSEFETVATQLLKRTQAMLNKYRCLLLEDAMRINPSAEMVMIDRMFNQEERASLSRDKRLALVDPEGFQADFCCSFKLDKAAHEMQFSRSDQHGGKTTSSVHLTAKAQSRDRAKAGLAEPMNHDQFHLVPNHIVVSAEGNISKKTDCLGRALKFDKVGSAQYRSASEEKTSRRDSAKGSECSPGPEGHRKNSSRPDHGPDSKLSSLLVDSQLEMTCNSSFQDKTLRNSPKNEVLHTDIMKGSGEPQPDLQLTKSLETTFKNILELKKAGRQSQSDPTVSGSVELDFPNFSPMASQENCLEKFIPDHSEGVVETDSILEAAVNSILEC", "length": 1098, "header": "tr|A0AAA9TZQ6-1|A0AAA9TZQ6_BOVIN Computationally mapped isoform of BICRA like chromatin remodeling complex associated protein OS=Bos taurus OX=9913 GN=BICRAL PE=4 SV=1 CANONICAL=E1BMP4-1" }, "locus": { "chromosome": "23", "start_pos": 16503034, "end_pos": 16460894, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000106203.1", "url": "https://www.ensembl.org/id/ENSBTAT00000106203.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102228.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102228.1" } ] } }, { "isoform_ac": "A0AAA9U283-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U283/entry", "sequence": { "sequence": "MEVVMDDDDDSCLLDLIGDPQALNYFLHGPSNKSSNEDLTNAGYSAANSNSIFANSSNADPKSALKAVSSQLGEGPSDGLPLSSSLQFLEDELESSPLPDLSEDQPFDILQKSLQEANITEQTLAEEAYLDASIGSSQQFAQAQLHPSSSASFTQASNVSNYSGQTLQPIGVTHVPVGTSFASNTVGVHHGFMHHVGISVPSQHLSNSSQISGSGQIQLIGSFGNQPSMMTINNLDGSQIILKGSGQQAPSNVSGGLLVHRQTPNGNSLFGNSSSSPVAQPVTVPFNSTNFQTSLPVHNIIIQRGLAPNSNKVPVNIQPKPIQMGQQNTYNVNNLGIQQHHVQQGISFASASSPQGSVVGPHMSVNIVNQQNTRKPVTSQSVSSAGGSIVIHSPMGQPHTPQSQFLIPTSLSVSSNSVHHVQTINGQLLQTQPSQLISGQVASEHVMLNRNSSNMLRTNQPYSGQMLNNQSAAVQLVSGQTFAASGSPVIVNHASPQIVGGQVPLQQASPTVLHLSPGQSSVSQGRPGFTTMPSVTSMAGPSRFPVSSSSTAHPSLGSAVQSGASGSNFTGDQLTQPNRTPGPVSVSHRLPVPSSKSTSTFSNTPGVGSQQQFFCQAQKKSLNQTSPISASKTTDGLRPAPMPGLLSTALPGQDSGSKVIPASLGTTQPQQEKVVGSPPGQPTVQVDGHPGGQKRPAAKQLTKGAFILQQLQRDQAHAVTPDKNQFRSLSDAVQRLLSYHVCQGSMPTEEDLRKVDSEFETVATQLLKRTQAMLNKYRCLLLEDAMRINPSAEMVMIDRMFNQEERASLSRDKRLALVDPEGFQADFCCSFKLDKAAHEMQFSRSDQHGGKTTSSVHLTAKAQSRDRAKAGLAEPMNHDQFHLVPNHIVVSAEGNISKKTDCLGRALKFDKVGSAQYRSASEEKTSRRDSAKGSECSPGPEGHRKNSSRPDHGPDSKLSSLLVDSQLEMTCNSSFQDKTLRNSPKNEVLHTDIMKGSGEPQPDLQLTKSLETTFKNILELKKAGRQSQSDPTVSGSVELDFPNFSPMASQENCLEKFIPDHSEGVVETDSILEAAVNSILEC", "length": 1082, "header": "tr|A0AAA9U283-1|A0AAA9U283_BOVIN Computationally mapped isoform of BICRA like chromatin remodeling complex associated protein OS=Bos taurus OX=9913 GN=BICRAL PE=4 SV=1 CANONICAL=E1BMP4-1" }, "locus": { "chromosome": "23", "start_pos": 16503034, "end_pos": 16414783, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096026.1", "url": "https://www.ensembl.org/id/ENSBTAT00000096026.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103526.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103526.1" } ] } }, { "isoform_ac": "E1BMP4-1", "url": "https://www.uniprot.org/uniprotkb/E1BMP4/entry", "sequence": { "sequence": "MEFSKQEYWSGVRLPSSAPMLVVMDDDDDSCLLDLIGDPQALNYFLHGPSNKSSNEDLTNAGYSAANSNSIFANSSNADPKSALKAVSSQLGEGPSDGLPLSSSLQFLEDELESSPLPDLSEDQPFDILQKSLQEANITEQTLAEEAYLDASIGSSQQFAQAQLHPSSSASFTQASNVSNYSGQTLQPIGVTHVPVGTSFASNTVGVHHGFMHHVGISVPSQHLSNSSQISGSGQIQLIGSFGNQPSMMTINNLDGSQIILKGSGQQAPSNVSGGLLVHRQTPNGNSLFGNSSSSPVAQPVTVPFNSTNFQTSLPVHNIIIQRGLAPNSNKVPVNIQPKPIQMGQQNTYNVNNLGIQQHHVQQGISFASASSPQGSVVGPHMSVNIVNQQNTRKPVTSQSVSSAGGSIVIHSPMGQPHTPQSQFLIPTSLSVSSNSVHHVQTINGQLLQTQPSQLISGQVASEHVMLNRNSSNMLRTNQPYSGQMLNNQSAAVQLVSGQTFAASGSPVIVNHASPQIVGGQVPLQQASPTVLHLSPGQSSVSQGRPGFTTMPSVTSMAGPSRFPVSSSSTAHPSLGSAVQSGASGSNFTGDQLTQPNRTPGPVSVSHRLPVPSSKSTSTFSNTPGVGSQQQFFCQAQKKSLNQTSPISASKTTDGLRPAPMPGLLSTALPGQDSGSKVIPASLGTTQPQQEKVVGSPPGQPTVQVDGHPGGQKRPAAKQLTKGAFILQQLQRDQAHAVTPDKNQFRSLSDAVQRLLSYHVCQGSMPTEEDLRKVDSEFETVATQLLKRTQAMLNKYRCLLLEDAMRINPSAEMVMIDRMFNQEERASLSRDKRLALVDPEGFQADFCCSFKLDKAAHEMQFSRSDQHGGKTTSSVHLTAKAQSRDRAKAGLAEPMNHDQFHLVPNHIVVSAEGNISKKTDCLGRALKFDKVGSAQYRSASEEKTSRRDSAKGSECSPGPEGHRKNSSRPDHGPDSKLSSLLVDSQLEMTCNSSFQDKTLRNSPKNEVLHTDIMKGSGEPQPDLQLTKSLETTFKNILELKKAGRQSQSDPTVSGSVELDFPNFSPMASQENCLEKFIPDHSEGVVETDSILEAAVNSILEC", "length": 1101, "header": "tr|E1BMP4-1|E1BMP4_BOVIN Isoform 1 of BICRA like chromatin remodeling complex associated protein OS=Bos taurus OX=9913 GN=BICRAL PE=4 SV=2 CANONICAL=E1BMP4-1" }, "locus": { "chromosome": "23", "start_pos": 16503034, "end_pos": 16441089, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019726.4", "url": "https://www.ensembl.org/id/ENSBTAT00000019726.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019726.3", "url": "https://www.ensembl.org/id/ENSBTAP00000019726.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-9933947", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9933947", "resource": "Reactome", "description": "Formation of the non-canonical BAF (ncBAF) complex" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "SWI/SNF complex", "id": "GO:0016514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016514", "evidence": [ { "database": "UniProtKB", "id": "E1BMP4", "url": "https://www.uniprot.org/uniprotkb/E1BMP4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "E1BMP4", "url": "https://www.uniprot.org/uniprotkb/E1BMP4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1062, "end_pos": 1064, "annotation": "n_glycosylation_sequon" }, { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 180, "end_pos": 182, "annotation": "n_glycosylation_sequon" }, { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 470, "end_pos": 472, "annotation": "n_glycosylation_sequon" }, { "start_pos": 488, "end_pos": 490, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" }, { "start_pos": 587, "end_pos": 589, "annotation": "n_glycosylation_sequon" }, { "start_pos": 597, "end_pos": 599, "annotation": "n_glycosylation_sequon" }, { "start_pos": 642, "end_pos": 644, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" }, { "start_pos": 914, "end_pos": 916, "annotation": "n_glycosylation_sequon" }, { "start_pos": 965, "end_pos": 967, "annotation": "n_glycosylation_sequon" }, { "start_pos": 991, "end_pos": 993, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP4" }, { "id": "PF15249", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15249" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GLTSCR protein conserved", "eco_id": "ECO_0000259", "start_pos": 733, "end_pos": 833, "start_aa": "Asp", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1062, "end_pos": 1064 }, { "start_pos": 137, "end_pos": 139 }, { "start_pos": 177, "end_pos": 179 }, { "start_pos": 180, "end_pos": 182 }, { "start_pos": 226, "end_pos": 228 }, { "start_pos": 271, "end_pos": 273 }, { "start_pos": 291, "end_pos": 293 }, { "start_pos": 306, "end_pos": 308 }, { "start_pos": 470, "end_pos": 472 }, { "start_pos": 488, "end_pos": 490 }, { "start_pos": 51, "end_pos": 53 }, { "start_pos": 587, "end_pos": 589 }, { "start_pos": 597, "end_pos": 599 }, { "start_pos": 642, "end_pos": 644 }, { "start_pos": 74, "end_pos": 76 }, { "start_pos": 914, "end_pos": 916 }, { "start_pos": 965, "end_pos": 967 }, { "start_pos": 991, "end_pos": 993 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BNI4-1", "uniprot_ac": "E1BNI4", "uniprot_id": "E1BNI4_BOVIN", "mass": { "chemical_mass": 56014.0, "monoisotopic_mass": 56014.0 }, "refseq": { "ac": "NP_001179786", "name": "membrane-bound 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[], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNI4", "url": "https://www.uniprot.org/uniprotkb/E1BNI4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MBOAT1", "url": "https://www.uniprot.org/uniprotkb/E1BNI4", "locus": { "chromosome": "23", "start_pos": 37834104, "end_pos": 37723893, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016519", "url": "https://www.ensembl.org/id/ENSBTAG00000016519" } ] } } ], "crossref": [ { "id": "E1BNI4", "url": "https://alphafold.ebi.ac.uk/entry/E1BNI4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016519", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016519", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "541284", "url": "https://www.ncbi.nlm.nih.gov/gene/541284", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049941", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049941", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:541284", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:541284", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YVVMQAA", "url": "https://omabrowser.org/oma/group/YVVMQAA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LKG6", "url": "https://www.orthodb.org/?gene=A0A3Q1LKG6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M2F2", "url": "https://www.orthodb.org/?gene=A0A3Q1M2F2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BNI4", "url": "https://www.orthodb.org/?gene=E1BNI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13906", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13906", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13906:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13906:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03062", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03062", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1482801", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1482801", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-1482839", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1482839", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179786", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179786", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LKG6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LKG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M2F2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2F2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M2F2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2F2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S1E7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1E7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S1E7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1E7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SKS9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SKS9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKS9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T5X3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5X3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T5X3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5X3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNI4", "url": "https://www.uniprot.org/uniprotkb/E1BNI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNI4-1", "url": "https://www.uniprot.org/uniprotkb/E1BNI4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQDGSGAYRTTGSTCLHPLSELLGIPLDQVNFVACQLSALCAAFWFRLYLSPGETSPAVRHAFATIFGIYFVIFCFGWYSVHLFVLVLMCYGIMVTASISNIHRYSFFVAMGYLTICHISRIYIFHYGILTTDFSGPLMIVTQKITTLAFQVHDGLGRRAEDLSSEQHRLAVKAKPSFLEYVSYLLNFMSVIAGPCNNFKDYVAFIEGRHTHMKLLEVNWKEKGFHSLPEPSPTGAVMHKLCVTLVSLLLFLTLTKTFPVTSLVDDWFVHEANFLTRLCYLYIVMQASKPKYYFAWTLADAVNNAAGFGFSGVDKNGNFSWDLLSNLNIWKIETATSFKMYVENWNIQTATWLKRVCYERVPWYPTVLTFILSALWHGVYPGYYFTFLTGILVTLAARTVRKNYRHYFLSSKALKAVYDIVTWAVTQLAVSYTVAPFVMLAVEPTISLYKSMYFYLHIISLLIILFLPIKPQAHNQRWPQTLNSLNKKMD", "length": 490, "header": "tr|E1BNI4-1|E1BNI4_BOVIN Isoform 1 of Membrane bound O-acyltransferase domain containing 1 OS=Bos taurus OX=9913 GN=MBOAT1 PE=4 SV=1 CANONICAL=E1BNI4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LKG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG6/entry", "sequence": { "sequence": "MQDGSGAYRTTGSTCLHPLSELLGIPLDQVNFVACQLSALCAAFWFRLYLSPGETSPAVRHAFATIFGIYFVIFCFGWYSVHLFVLVLMCYGIMVTASISNIHRPLMIVTQKITTLAFQVHDGLGRRAEDLSSEQHRLAVKAKPSFLEYVSYLLNFMSVIAGPCNNFKDYVAFIEGRHTHMKLLEVNWKEKGFHSLPEPSPTGAVMHKLCVTLVSLLLFLTLTKTFPVTSLVDDWFVHEANFLTRLCYLYIVMQASKPKYYFAWTLADAVNNAAGFGFSGVDKNGNFSWDLLSNLNIWKIETATSFKMYVENWNIQTATWLKRVCYERVPWYPTVLTFILSALWHGVYPGYYFTFLTGILVTLAARTVRKNYRHYFLSSKALKAVYDIVTWAVTQLAVSYTVAPFVMLAVEPTISLYKSMYFYLHIISLLIILFLPIKPQAHNQRWPQTLNSLNKKMD", "length": 458, "header": "tr|A0A3Q1LKG6-1|E1BNI4_BOVIN Computationally mapped isoform of Membrane bound O-acyltransferase domain containing 1 OS=Bos taurus OX=9913 GN=MBOAT1 PE=4 SV=1 CANONICAL=E1BNI4-1" }, "locus": { "chromosome": "23", "start_pos": 37833445, "end_pos": 37724094, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066356.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066356.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057140.1", "url": "https://www.ensembl.org/id/ENSBTAP00000057140.1" } ] } }, { "isoform_ac": "A0A3Q1M2F2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2F2/entry", "sequence": { "sequence": "MSRSGLTVNFVACQLSALCAAFWFRLYLSPGETSPAVRHAFATIFGIYFVIFCFGWYSVHLFVLVLMCYGIMVTASISNIHRYSFFVAMGYLTICHISRIYIFHYGILTTDFSGPLMIVTQKITTLAFQVHDGLGRRAEDLSSEQHRLAVKAKPSFLEYVSYLLNFMSVIAGPCNNFKDYVAFIEGRHTHMKLLEVNWKEKGFHSLPEPSPTGAVMHKLCVTLVSLLLFLTLTKTFPVTSLVDDWFVHEANFLTRLCYLYIVMQASKPKYYFAWTLADAVNNAAGFGFSGVDKNGNFSWDLLSNLNIWKIETATSFKMYVENWNIQTATWLKRVCYERVPWYPTVLTFILSALWHGVYPGYYFTFLTGILVTLAARTVRKNYRHYFLSSKALKAVYDIVTWAVTQLAVSYTVAPFVMLAVEPTISLYKSMYFYLHIISLLIILFLPIKPQAHNQRWPQTLNSLNKKMD", "length": 468, "header": "tr|A0A3Q1M2F2-1|A0A3Q1M2F2_BOVIN Computationally mapped isoform of Membrane bound O-acyltransferase domain containing 1 OS=Bos taurus OX=9913 GN=MBOAT1 PE=4 SV=1 CANONICAL=E1BNI4-1" }, "locus": { "chromosome": "23", "start_pos": 37833445, "end_pos": 37737153, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078086.3", "url": "https://www.ensembl.org/id/ENSBTAT00000078086.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063960.1", "url": "https://www.ensembl.org/id/ENSBTAP00000063960.1" } ] } }, { "isoform_ac": "A0AAA9S1E7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1E7/entry", "sequence": { "sequence": "MFLQKRSSEVLTPRWLDGITDPMEVNFVACQLSALCAAFWFRLYLSPGETSPAVRHAFATIFGIYFVIFCFGWYSVHLFVLVLMCYGIMVTASISNIHRYSFFVAMGYLTICHISRIYIFHYGILTTDFSGPLMIVTQKITTLAFQVHDGLGRRAEDLSSEQHRLAVKAKPSFLEYVSYLLNFMSVIAGPCNNFKDYVAFIEGRHTHMKLLEVNWKEKGFHSLPEPSPTGAVMHKLCVTLVSLLLFLTLTKTFPVTSLVDDWFVHEANFLTRLCYLYIVMQASKPKYYFAWTLADAVNNAAGFGFSGVDKNGNFSWDLLSNLNIWKIETATSFKMYVENWNIQTATWLKRVCYERVPWYPTVLTFILSALWHGVYPGYYFTFLTGILVTLAARTVRKNYRHYFLSSKALKAVYDIVTWAVTQLAVSYTVAPFVMLAVEPTISLYKSMYFYLHIISLLIILFLPIKPQAHNQRWPQTLNSLNKKMD", "length": 485, "header": "tr|A0AAA9S1E7-1|A0AAA9S1E7_BOVIN Computationally mapped isoform of Membrane bound O-acyltransferase domain containing 1 OS=Bos taurus OX=9913 GN=MBOAT1 PE=4 SV=2 CANONICAL=E1BNI4-1" }, "locus": { "chromosome": "23", "start_pos": 37833445, "end_pos": 37772115, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000106074.2", "url": "https://www.ensembl.org/id/ENSBTAT00000106074.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078816.2", "url": "https://www.ensembl.org/id/ENSBTAP00000078816.2" } ] } }, { "isoform_ac": "A0AAA9SKS9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKS9/entry", "sequence": { "sequence": "MFLQKRSSEVLTPRWLDGITDPMEVNFVACQLSALCAAFWFRLYLSPGETSPAVRHAFATIFGIYFVIFCFGWYSVHLFVLVLMCYGIMVTASISNIHRYSFFVAMGYLTICHISRIYIFHYGILTTDFSGPLMIVTQKITTLAFQVHDGLGRRAEDLSSEQHRLAVKAKPSFLEYVSYLLNFMSVIAGPCNNFKDYVAFIEGRHTHMKLLEVNWKEKGFHSLPEPSPTGAVMHKLCVTLVSLLLFLTLTKTFPVTSLVDDWFVHEANFLTRLCYLYIVMQASKPKYYFAWTLADAVNNAAGFGFSGVDKNGNFSWDLLSNLNIWKIETATSFKMYVENWNIQTATWLKRVCYERVPWYPTVLTFILSALWHGVYPGYYFTFLTGILVTLAARTVRKNYRHYFLSSKALKAVYDIVTWAVTQLAVSYTVAPFVMLAVEPTISLYKSALSSRSFYRD", "length": 456, "header": "tr|A0AAA9SKS9-1|A0AAA9SKS9_BOVIN Computationally mapped isoform of Membrane bound O-acyltransferase domain containing 1 OS=Bos taurus OX=9913 GN=MBOAT1 PE=4 SV=1 CANONICAL=E1BNI4-1" }, "locus": { "chromosome": "23", "start_pos": 37826657, "end_pos": 37772115, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000117852.1", "url": "https://www.ensembl.org/id/ENSBTAT00000117852.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085895.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085895.1" } ] } }, { "isoform_ac": "A0AAA9T5X3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5X3/entry", "sequence": { "sequence": "MQDGSGAYRTTGSTCLHPLSELLGIPLDQVNFVACQLSALCAAFWFRLYLSPGETSPAVRHAFATIFGIYFVIFCFGWYSVHLFVLVLMCYGIMVTASISNIHRYSFFVAMGYLTICHISRIYIFHYGILTTDFSGPLMIVTQKITTLAFQVHDGLGRRAEDLSSEQHRLAVKAKPSFLEYVSYLLNFMSVIAGPCNNFKDYVAFIEGRHTHMKLLEVNWKEKGFHSLPEPSPTGAVMHKLCVTLVSLLLFLTLTKTFPVTSLVDDWFVHEANFLTRLCYLYIVMQASKPKYYFAWTLADAVNNAAGFGFSGVDKNGNFSWDLLSNLNIWKIETATSFKMYVENWNIQTATWLKRVCYERVPWYPTVLTFILSALWHGVYPGYYFTFLTGILVTLAARTVRKNYRHYFLSSKALKAVYDIVTWAVTQLAVSYTVAPFVMLAVEPTISLYKHQDTLICIPKSDAWG", "length": 465, "header": "tr|A0AAA9T5X3-1|A0AAA9T5X3_BOVIN Computationally mapped isoform of Membrane bound O-acyltransferase domain containing 1 OS=Bos taurus OX=9913 GN=MBOAT1 PE=4 SV=1 CANONICAL=E1BNI4-1" }, "locus": { "chromosome": "23", "start_pos": 37825347, "end_pos": 37724094, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119268.1", "url": "https://www.ensembl.org/id/ENSBTAT00000119268.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093251.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093251.1" } ] } }, { "isoform_ac": "E1BNI4-1", "url": "https://www.uniprot.org/uniprotkb/E1BNI4/entry", "sequence": { "sequence": "MQDGSGAYRTTGSTCLHPLSELLGIPLDQVNFVACQLSALCAAFWFRLYLSPGETSPAVRHAFATIFGIYFVIFCFGWYSVHLFVLVLMCYGIMVTASISNIHRYSFFVAMGYLTICHISRIYIFHYGILTTDFSGPLMIVTQKITTLAFQVHDGLGRRAEDLSSEQHRLAVKAKPSFLEYVSYLLNFMSVIAGPCNNFKDYVAFIEGRHTHMKLLEVNWKEKGFHSLPEPSPTGAVMHKLCVTLVSLLLFLTLTKTFPVTSLVDDWFVHEANFLTRLCYLYIVMQASKPKYYFAWTLADAVNNAAGFGFSGVDKNGNFSWDLLSNLNIWKIETATSFKMYVENWNIQTATWLKRVCYERVPWYPTVLTFILSALWHGVYPGYYFTFLTGILVTLAARTVRKNYRHYFLSSKALKAVYDIVTWAVTQLAVSYTVAPFVMLAVEPTISLYKSMYFYLHIISLLIILFLPIKPQAHNQRWPQTLNSLNKKMD", "length": 490, "header": "tr|E1BNI4-1|E1BNI4_BOVIN Isoform 1 of Membrane bound O-acyltransferase domain containing 1 OS=Bos taurus OX=9913 GN=MBOAT1 PE=4 SV=1 CANONICAL=E1BNI4-1" }, "locus": { "chromosome": "23", "start_pos": 37833445, "end_pos": 37724094, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021975.8", "url": "https://www.ensembl.org/id/ENSBTAT00000021975.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021975.5", "url": "https://www.ensembl.org/id/ENSBTAP00000021975.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:541284", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:541284", "resource": "KEGG Pathway" }, { "id": "R-BTA-1482801", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1482801", "resource": "Reactome", "description": "Acyl chain remodelling of PS" }, { "id": "R-BTA-1482839", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1482839", "resource": "Reactome", "description": "Acyl chain remodelling of PE" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IZC9-1", "protein_name": "Lysophospholipid acyltransferase 1", "gene_name": "mboat1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDKKKNIDIAFKTTGCTWLSPVSDQVGVPLDQVNFIACQLFGLAAAFWFRLFLSPQRATPEVRHAVAAILGASSVMFCFGWYAVHIFILVLACYGIMIKASVRNVHRYTMVASIGYLTACQVSRVFIFDYGILSTDFSGPLMMITQKITSLAFQVYDGMGRKQEELKDDQRQLAVHSKPSLLEYLSYNINFLSVLVGPCSNYKDYEEFIKGQHVQHRLKRVKDGSLQQNGWDKVPEPSPVRTVITKVLVCVCCLLWFFIITRAFPIKYNVDPQFITEASFISRLAYAFVSIQAARPKFYFAWTLADAVHNAAGYGVSGVNERGEVSWDLVSNVRIWEIETATSFKSFIDNWNIQTGLWLKRVCYDRAPFYRTPLTFVLSAIWHGVYPGYYFTFITAIPITLAARSVRRNFRKYFLSSRQLKACYDVVTWGATQLTICYTVMPFLLLALEPTLKYYRSMYFHVHVISILAMILLPGKPKSFKPENHDLHSNNNVKED", "length": 496 }, "evidence": [ { "id": "E1BNI4", "url": "https://omabrowser.org/oma/group/E1BNI4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A481CBJ8-1", "protein_name": "Membrane bound O-acyltransferase domain containing 1", "gene_name": "MBOAT1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAEPPSSLSYRTTGSTCLHPLSELLGIPLDQVNFVACQLFALFAAFWFRIYLSPGKTSPDVRHAFATIFGIYFVIFCFGWYSLHLFVLVLMCYGLMVTASVSNIHRYSFFVAMGYLTICHISRIYIFHYGILTTDFSGPLMIVTQKITTLAFQVHDGLGRRAEDLSTEQHRLAVKAKPSFLEYLSYLLNFMSVIAGPCNNFKDYVAFIEGRHTHMKLLEVNWKEKGFHSLPEPSPTGAVIHKLCMTLVSLLLFLTLTKTFPVTCLVDDWFVHKANFLTRLCYLYVVMQASKPKYYFAWTLADAVNNAAGFGFSGVDKNGNFSWDLLSNLNIWKIETATSFKMYLENWNIQTATWLKRVCYERVPWYPTVLTFILSALWHGVYPGYYFTFLTGILVTLAARTVRNNYRHYFLSSKALKVLYDIVTWAVTQLAVSYTVAPFVMLAVEPTISLYKSMYFYLHIISLLIILFLPIKPQAHTQRRPPTLNSKKKTD", "length": 492 }, "evidence": [ { "id": "E1BNI4", "url": "https://omabrowser.org/oma/group/E1BNI4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1LV18-1", "protein_name": "Membrane bound O-acyltransferase domain containing 1", "gene_name": "Mboat1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAARSPASLSYRTTGSTCLHPLSQLLGIPLDQVNFVACQLLALSAAFWFRIYLRPGKASPEVRHTLATILGIYFVVFCFGWYAVHLFVLVLMCYGVMVTASVSNIHRYSFFVAMGYLTICHISRIYIFHYGILTTDFSGPLMIVTQKITTLAFQVHDGLGRKAEDLSAEQHRLAVKVKPSLLEYLSYHLNFMSVIAGPCNNFKDYVAFIEGRHIHMKLLEVNWKERGFQSLPEPSPTGAVIQKLCITLMSLLLFLTLSKSFPVTFLIDDWFVHKANFLSRLWYLYVVMQAAKPKYYFAWTLADAVHNAAGFGFSGIDADGNSCWDLLSNLNIWKIETATSFKMYLENWNIQTSTWLKCVCYERVPWYPTVLTFLLSALWHGVYPGYYFTFLTGVPVTLAARAVRNNYRHHFLASKARKVAYDVVTWAVTQLAVSYTAAPFVMLAVEPTISLYKSMFFFLHILCLLIILLLPVKPRQPQRQSQSPNSVKKKAD", "length": 492 }, "evidence": [ { "id": "E1BNI4", "url": "https://omabrowser.org/oma/group/E1BNI4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3GWW5-1", "protein_name": "Lysophospholipid acyltransferase 1 isoform X1", "gene_name": "Mboat1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAARPPVSLSYRTTGSTCLHPLSQLLGIPLDQVNFVACQLFALSAAFWFRIYLHPGKASPEVRHALATILGIYFVVFCFGWYAVHLFVLVLMCYGVMVTASISNIHRYSFLVAMGYLTICHISRIYIFHYGILTTDFSGPLMIVTQKITTLAFQIHDGLGRKAEDLSAEQHRLAVKVKPSLLEYLSYHLNFMSIIAGPCNNFKDYAAFIEGRHIHMKLLEVNWKQRGFHSLPEPSPSAAVIQKLCMTLMSLLLFLTLSKSFPVTFLIDDWFVHKANFLSRLWYLYVVMQAAKPKYYFAWTLADAVHNAAGFGFSGVDADGHFCWDLLSNLNIWKIETATSFKMYLENWNIQTSAWLKCVCYERVPWYPTVFTFVLSALWHGVYPGYYFTFLTGVPVTLAARAVRNNYRHHFLSSKARKVAYDVVTWAATQLAISYTAAPFVLLAVEPTISLYKSMFFFLHIVSLLIIFFLPIKPRQPQRQPQSANSVKKKVD", "length": 492 }, "evidence": [ { "id": "E1BNI4", "url": "https://omabrowser.org/oma/group/E1BNI4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8BH98-1", "protein_name": "Membrane-bound glycerophospholipid O-acyltransferase 1", "gene_name": "Mboat1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAARPPASLSYRTTGSTCLHPLSQLLGIPLDQVNFVACQLFALSAAFWFRIYLHPGKASPEVRHTLATILGIYFVVFCFGWYAVHLFVLVLMCYGVMVTASVSNIHRYSFFVAMGYLTICHISRIYIFHYGILTTDFSGPLMIVTQKITTLAFQVHDGLGRKAEDLSAEQHRLAVKAKPSLLEYLSYHLNFMSVIAGPCNNFKDYVAFIEGRHIHMKLLEVNWTQRGFQSLPEPSPMGAVIQKLCVTLMSLLLFLTLSKSFPVTFLIDDWFVHKANFLSRLWYLYVVMQAAKPKYYFAWTLADAVHNAAGFGFNGMDTDGKSRWDLLSNLNIWKIETATSFKMYLENWNIQTSTWLKCVCYERVPWYPTVLTFLLSALWHGVYPGYYFTFLTGVPVTLAARAVRNNYRHHFLSSKARKIAYDVVTWAVTQLAVSYTAAPFVMLAVEPTISLYKSVFFFLHIICLLIILFLPIKPHQPQRQSRSPNSVKKKAD", "length": 492 }, "evidence": [ { "id": "E1BNI4", "url": "https://omabrowser.org/oma/group/E1BNI4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E1BNI4", "url": "https://www.uniprot.org/uniprotkb/E1BNI4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BNI4", "url": "https://www.uniprot.org/uniprotkb/E1BNI4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "acyltransferase activity", "id": "GO:0016746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016746", "evidence": [ { "database": "UniProtKB", "id": "E1BNI4", "url": "https://www.uniprot.org/uniprotkb/E1BNI4" } ], "pmid": "" }, { "name": "1-acylglycerophosphoserine O-acyltransferase activity", "id": "GO:0106263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106263", "evidence": [ { "database": "UniProtKB", "id": "E1BNI4", "url": "https://www.uniprot.org/uniprotkb/E1BNI4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "phosphatidylserine acyl-chain remodeling", "id": "GO:0036150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036150", "evidence": [ { "database": "UniProtKB", "id": "E1BNI4", "url": "https://www.uniprot.org/uniprotkb/E1BNI4" } ], "pmid": "" }, { "name": "lipid modification", "id": "GO:0030258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030258", "evidence": [ { "database": "UniProtKB", "id": "E1BNI4", "url": "https://www.uniprot.org/uniprotkb/E1BNI4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNI4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 490, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNI4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNI4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BNU8-1", "uniprot_ac": "E1BNU8", "uniprot_id": "E1BNU8_BOVIN", "mass": { "chemical_mass": 41111.0, "monoisotopic_mass": 41111.0 }, "refseq": { "ac": "NP_001180105", "name": "epoxide hydrolase 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180105" }, "gene_names": [ { "name": "EPHX3", "type": "recommended", "evidence": [ { "id": "E1BNU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNU8" } ] }, { "name": "ABHD9", "type": 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"species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNU8", "url": "https://www.uniprot.org/uniprotkb/E1BNU8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "EPHX3", "url": "https://www.uniprot.org/uniprotkb/E1BNU8", "locus": { "chromosome": "7", "start_pos": 7898344, "end_pos": 7891255, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020090", "url": "https://www.ensembl.org/id/ENSBTAG00000020090" } ] } } ], "crossref": [ { "id": "E1BNU8", "url": "https://alphafold.ebi.ac.uk/entry/E1BNU8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020090", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020090", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "617882", "url": "https://www.ncbi.nlm.nih.gov/gene/617882", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000639", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000639", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:617882", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617882", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QNWFSWR", "url": "https://omabrowser.org/oma/group/QNWFSWR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LKN8", "url": "https://www.orthodb.org/?gene=A0A3Q1LKN8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BNU8", "url": "https://www.orthodb.org/?gene=E1BNU8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43329", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43329", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001180105", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180105", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LKN8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LKN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNU8", "url": "https://www.uniprot.org/uniprotkb/E1BNU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNU8-1", "url": "https://www.uniprot.org/uniprotkb/E1BNU8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPELVVTALLAPSRLTLKLLRAFMWSLVFSAALVAAAVYGCIALTHVMCRPRRGFLGRPRHTPPVCLSDPTLGEHCFLILRSSGLRLHYVSAGRGKGPLMLFLHGFPENWFSWRYQLREFQSRFHVVAVDLRGYGPSDAPKDVDCYTIDLLMADIQDVILGLGYSKCILVAHDWGALLAWNFSIYYPSLVERMVVVSAAPMSVYQDYSLHHIGQFFRSNYVFLFQLPWLPEKLLSMSDFQILKTTLTHRKRGIPQLTPSELEAFLYDFSQPGGLTGPLNYYRNIFRTFPLEPQELATPTLLLWGEKDPYFEQGLVEAISSRFVPGRLEAHILPGMGHWIPQTNPVEMHQYMWAFLQDLLD", "length": 360, "header": "tr|E1BNU8-1|E1BNU8_BOVIN Isoform 1 of Epoxide hydrolase 3 OS=Bos taurus OX=9913 GN=EPHX3 PE=3 SV=1 CANONICAL=E1BNU8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LKN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKN8/entry", "sequence": { "sequence": "MPELVVTALLAPSRLTLKLLRAFMWSLVFSAALVAAAVYGCIALTHVMCRPRRGFLGRPRHTPPVCLSDPTLGEHCFLILRSSGLRLHYVSAGRGKGPLMLFLHGFPENWFSWRYQLREFQSRFHVVAVDLRGYGPSDAPKDVDCYTIDLLMADIQDVILGLGYSKCILVAHDWGALLAWNFSIYYPSLVERMVVVSAAPMSVYQDYSLHHIGQFFRSNYVFLFQLPWLPEKLLSMSDFQILKTTLTHRKRGIPQLTPSELEAFLYDFSQPGGLTGPLNYYRNIFRWQPTRLPHPWDSPGKNTGVCCHFLLQCMKVKVKSLSRVRLFATSWTAAHQAPPSMGFARQEY", "length": 348, "header": "tr|A0A3Q1LKN8-1|E1BNU8_BOVIN Computationally mapped isoform of Epoxide hydrolase 3 OS=Bos taurus OX=9913 GN=EPHX3 PE=3 SV=2 CANONICAL=E1BNU8-1" }, "locus": { "chromosome": "7", "start_pos": 7898232, "end_pos": 7892281, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084729.3", "url": "https://www.ensembl.org/id/ENSBTAT00000084729.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060193.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060193.2" } ] } }, { "isoform_ac": "E1BNU8-1", "url": "https://www.uniprot.org/uniprotkb/E1BNU8/entry", "sequence": { "sequence": "MPELVVTALLAPSRLTLKLLRAFMWSLVFSAALVAAAVYGCIALTHVMCRPRRGFLGRPRHTPPVCLSDPTLGEHCFLILRSSGLRLHYVSAGRGKGPLMLFLHGFPENWFSWRYQLREFQSRFHVVAVDLRGYGPSDAPKDVDCYTIDLLMADIQDVILGLGYSKCILVAHDWGALLAWNFSIYYPSLVERMVVVSAAPMSVYQDYSLHHIGQFFRSNYVFLFQLPWLPEKLLSMSDFQILKTTLTHRKRGIPQLTPSELEAFLYDFSQPGGLTGPLNYYRNIFRTFPLEPQELATPTLLLWGEKDPYFEQGLVEAISSRFVPGRLEAHILPGMGHWIPQTNPVEMHQYMWAFLQDLLD", "length": 360, "header": "tr|E1BNU8-1|E1BNU8_BOVIN Isoform 1 of Epoxide hydrolase 3 OS=Bos taurus OX=9913 GN=EPHX3 PE=3 SV=1 CANONICAL=E1BNU8-1" }, "locus": { "chromosome": "7", "start_pos": 7895523, "end_pos": 7892281, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026765.7", "url": "https://www.ensembl.org/id/ENSBTAT00000026765.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026765.5", "url": "https://www.ensembl.org/id/ENSBTAP00000026765.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:617882", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617882", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A4W4-1", "protein_name": "Epoxide hydrolase 3", "gene_name": "Ephx3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCGGSLYPSRASVSSAGPVDPDSTVETQNKGGGLPAPAPPAQSSDHGSVVVPERKDMPEFVVTALLAPSRLSLKLLRALVMILVYLAALVAAFVYSCVALTNVLCHPRRGCCGRQRSAPECLRDPTLGEHCFLTLRSSGLRLHYVSAGRGNGPLMLFLHGFPENWFSWRYQLREFQSHFHVVAVDLRGYSPSDAPKDVDCYTVDLLLTDIKDIILGLGYSKCILVSHDWGAALAWDFSVYFPSLVDRMIVVSGPPMSVFQEYSTRHIGQLFRSNYIFLFQLPWLPEKLLSLSDFQILKSIFTHHKKGIPRLSPCELEAFLYPFSHPGGLSGPINYYRNVFRNFPLEPKELSKPTLLLWGEKDFSLQQGLVEAIESHFVPGRLESHILPGSGHWIPQSHPEEMHQYMWAFLQDLLG", "length": 415 }, "evidence": [ { "id": "E1BNU8", "url": "https://omabrowser.org/oma/group/E1BNU8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LC51-1", "protein_name": "Epoxide hydrolase 3", "gene_name": "EPHX3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPELVVTALLAPSRLTLKLLRAFMWSLVFSAALVAAAVYGCIALTHVLCRPRRGCCGRPRRTPPACLNDPTLGEHCFLTLKSSGVHLHYVSAGRGNGPLMLFLHGFPENWFSWRYQIREFQSHFHVVAVDLRGYGSSDAPSDMDCYTIDLLMADIQDVILGLGYSKCILVAHDWGALLAWNFSIYYPSLVERMVVVSAAPMSVYQDYSMRHISQFFRSNYVFLFQLPWLPEKLLSMSDFQILKTTLTHRKRGIPHLTPNELEAFLYDFSQPGGLTGPLNYYRNLFRNFPLEPQELATRTLLLWGEKDPYLEQGLVGAISSRFVPGRLEAHILPGVGHWIPQSNAEEMHQYMWTFLQDLLN", "length": 360 }, "evidence": [ { "id": "E1BNU8", "url": "https://omabrowser.org/oma/group/E1BNU8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3V1F8-1", "protein_name": "Epoxide hydrolase 3", "gene_name": "Ephx3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPEFVVTALLAPSRLSLKLLRALVMSLVYLAALVAAFVYSCIALTHVMCRPRRGCCGRQRLSPPECLRDPTLGEHCFLTLRVSVPPVKSSGLRLHYVSAGHGNGPLMLFLHGFPENWFSWRYQLREFQSHFHVVAVDMRGYSPSDAPKEVDCYTIDLLLDDIKDTILGLGYSKCILVSHDWGASLAWEFSIYYPSLVERMVVANGPPMSVIQEYSIHHIGQIFRSNYMFLFQLPWLPEKLLSMSDFQILKDTFTHRKNGIPGLTPSELEAFLYHFSQPGCLTGPINYYRNVFRNFPLEPKKLSTPTLLLWGEKDFAFQQGLVEAIGRHFVPGRLESHILPGSGHWIPQSHPQEMHQYMWAFLQDLLG", "length": 367 }, "evidence": [ { "id": "E1BNU8", "url": "https://omabrowser.org/oma/group/E1BNU8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H6B9-1", "protein_name": "Epoxide hydrolase 3", "gene_name": "EPHX3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPELVVTALLAPSRLSLKLLRAFMWSLVFSVALVAAAVYGCIALTHVLCRPRRGCCGRRRSASPACLSDPSLGEHGFLNLKSSGLRLHYVSAGRGNGPLMLFLHGFPENWFSWRYQLREFQSRFHVVAVDLRGYGPSDAPRDVDCYTIDLLLVDIKDVILGLGYSKCILVAHDWGALLAWHFSIYYPSLVERMVVVSGAPMSVYQDYSLHHISQFFRSHYMFLFQLPWLPEKLLSMSDFQILKTTLTHRKTGIPCLTPSELEAFLYNFSQPGGLTGPLNYYRNLFRNFPLEPQELTTPTLLLWGEKDTYLELGLVEAIGSRFVPGRLEAHILPGIGHWIPQSNPQEMHQYMWAFLQDLLD", "length": 360 }, "evidence": [ { "id": "E1BNU8", "url": "https://omabrowser.org/oma/group/E1BNU8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "epoxide hydrolase activity", "id": "GO:0004301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004301", "evidence": [ { "database": "UniProtKB", "id": "E1BNU8", "url": "https://www.uniprot.org/uniprotkb/E1BNU8" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "E1BNU8", "url": "https://www.uniprot.org/uniprotkb/E1BNU8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BNU8", "url": "https://www.uniprot.org/uniprotkb/E1BNU8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "epoxide metabolic process", "id": "GO:0097176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097176", "evidence": [ { "database": "UniProtKB", "id": "E1BNU8", "url": "https://www.uniprot.org/uniprotkb/E1BNU8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNU8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 360, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNU8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNU8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BNU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNU8" }, { "id": "PF00561", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00561" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AB hydrolase-1", "eco_id": "ECO_0000259", "start_pos": 98, "end_pos": 339, "start_aa": "Pro", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 181, "end_pos": 183 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1MF92-1", "uniprot_ac": "F1MF92", "uniprot_id": "F1MF92_BOVIN", "mass": { "chemical_mass": 173259.0, "monoisotopic_mass": 173259.0 }, "refseq": {}, "gene_names": [ { "name": "ZMYM4", "type": "recommended", "evidence": [ { "id": "F1MF92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF92" } ] }, { "name": "ZMYM6", "type": "recommended", "evidence": [ { "id": "F1MF92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF92" } ] }, { "name": "ZMYM4", "type": "synonym", "evidence": [ { "id": "F1MF92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF92" } ] } ], "protein_names": [ { "name": "Zinc finger MYM-type containing 4", "type": "synonym", "evidence": [ { "id": "F1MF92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF92/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1MF92", "url": "https://www.uniprot.org/uniprotkb/F1MF92" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZMYM6", "url": "https://www.uniprot.org/uniprotkb/F1MF92", "locus": { "chromosome": "3", "start_pos": 110694119, "end_pos": 110648534, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021948", "url": "https://www.ensembl.org/id/ENSBTAG00000021948" } ] } } ], "crossref": [ { "id": "F1MF92", "url": "https://alphafold.ebi.ac.uk/entry/F1MF92", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021023", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021023", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSBTAG00000021948", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021948", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "529962", "url": "https://www.ncbi.nlm.nih.gov/gene/529962", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "618234", "url": "https://www.ncbi.nlm.nih.gov/gene/618234", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010507", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010507", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011017", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011017", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021893", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021893", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051284", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051284", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:618234", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618234", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NLFCVLA", "url": "https://omabrowser.org/oma/group/NLFCVLA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LKZ2", "url": "https://www.orthodb.org/?gene=A0A3Q1LKZ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MF92", "url": "https://www.orthodb.org/?gene=F1MF92", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MHR5", "url": "https://www.orthodb.org/?gene=F1MHR5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45736", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45736", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45736:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45736:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45736:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45736:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06467", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06467", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12012", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12012", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24900", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24900", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27073", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27073", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LKZ2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LKZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LY03", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LY03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LY03-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LY03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MF92", "url": "https://www.uniprot.org/uniprotkb/F1MF92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MF92-1", "url": "https://www.uniprot.org/uniprotkb/F1MF92-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MHR5", "url": "https://www.uniprot.org/uniprotkb/F1MHR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MHR5-1", "url": "https://www.uniprot.org/uniprotkb/F1MHR5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEREVESGPRKRVGEFEQKTGAVFDEIVENCGGIMDTEMSEDIDHNLTPTLDSMSYGMPNQTGSENSLLDEDDYFLNSGDLAGIPVVGSDNEDEQDFSSKDNLVSSIHTDDSLEVERRVTQHESDNENEIQIQNKLKKDFPKQFDQVSVFKSIRKDFSLVRENSKETFSGKEKNRDLTYHEREKRLDKPHKELDSRLKSSFFDKAANQVEETLHTHLPQTPETNFRDSSYPFANKESIGSELGNSFASNIRIKEEPLDDEYDKAMAPQQGLLDRIKDEPDNAQEYSHGQQQKTQEGELKISAVFSVSGSPLAPQLTTGFQPSLASSGMNKMLPSVPATAVRVSCSGCKKILQKGQTAYQRKGSTQLFCSTLCLTGYTVPPARPPPPPTKKTCSSCSKDILNPKDVISAQFENTTTSKDFCSQSCLSTYELKRKPVVTINTNSISTKCSMCQKNAVIRHEVNYQNVVHKLCSDACFSKFRSANNLTMNCCENCGGYCYSGSGQCHMLQIEGQSKKFCSSTCVTAYKQKSAKITPCALCKSLRSSAEMIENTNSLGKTELFCSVNCLSAYRVKMVTSAGVQVQCNSCKTSAIPQYHLAMSDGSIRNFCSYSCVVAFQNLFNKPAGMNSSVVPLSQGQVIVSIPTGSTVSAGGGNTSAVSPTSISSSAAAGLQRLAAQSQHVGFARSVVKLKCQHCNRLFATKPELLDYKGKMFQFCGKNCSDEYKKINNVMAMCEYCKIEKIIKETVRFSGADKSFCSEGCKLLYKHDLAKRWGNHCKMCSYCLQTSPKLVQNNLGGKVEEFCCEECMSKYTVLLCQMAKCDGCKRQGKLSESLKWRGEMKHFCNLLCILMFCNQQSMCDPPSQNNAASISMVPAASAGPPSLRKDSTPVIANVVSLASAPAAQPTVNSNSVLQGAVPTVTAKIIGDASTQTDVLKLPPSQPPRLLKNKALLCKPITQTKATSCKPHTQNKECQTEDTPAQPQIIAVPVPVPVFVPVPLHLYTQYAPVPFGIPVPMPVPMLIPSSMGNEDKVTESIEDIKEKLPSHPFEADLLEMAEMIAEDEEKEKTLSQGESQTSEQELFLDTKIFEKDQGSTYSGDLESEAVSTPHSWEEELNHYALKSNTVQEADLEVKQFSKGETEQDLEADFPSESFDPLNKGQGIQVRSRTRRRHRDGFPQPRRRGRKKSIVSVEPRSLIQGAFQGCSVSGMTLKYMYGVNAWRNWVQWKNAKEEQGDLKCGGVEHASSSPCSDPLGSTQEHALSQESSEPGCKVRSIKLKEDILSCTFAELSLGLCQFIQEVRRPNGEKYDPDSILYLCLGIQQYLFENGRIDNIFTEPYSRFMIELTKLLKIWEPTILPNGYMFSRIEEEHLWECKQLGAYSPIVLLNTLLFFNTKYFQLRNVTEHLQLSFAHVMRRTRTLKYSTKMTYLRFFPPSQKQESEPDKLTIGKRKRNEDDDVPVGVEMAENTDNPLRCPVRLYEFYLSKCSESVKQRNDVFYLQPERSCVPNSPMWYSTFPIDPGTLDTMLTRILMVREVHEELAKAKSEDSDVELSD", "length": 1553, "header": "tr|F1MF92-1|F1MF92_BOVIN Isoform 1 of Zinc finger MYM-type containing 4 OS=Bos taurus OX=9913 GN=ZMYM6 PE=4 SV=4 CANONICAL=F1MF92-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LKZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKZ2/entry", "sequence": { "sequence": "MKEPLDGECGKALAPQQALLDKIKEEPDNAQEYIHASKPKAQESELKISAVFSVSDSPLAQQLTPGFQLSLASSGPNVSLPSVPAVALQVFCSGCKKMLYKGQTAFHKTGSTQLFCSTRCIIGHSSSVCLLPPPKKTCANCSKDILNPKDVITTQFENSSPSKDFCSQSCLSSYELKRKPVVTIYTNSISTKCSMCQKNADIRFEVKYQNVVHGLCSDACFSKFHSTNNLTMNCCENCGSYCYSSSGPCQSQKVFSSTSIMAYKQNSAQTPPYALGKSLRPSAEMIETTNDSGKTELFCSINCLSAYRVKTVTSSGVQVLCHSCKTSAVPQYHLAMSNGTIHSFCSSSCVVAFQNVFNKPKGANSSAVPVSQTQVIVSPPSGSAVSAGRGHTSAFSPRSVSGSVAASLQPPAQFQQVALTHRIVRLRCQHCNHLFATKPELLFYKGRMFLFCGKLCSDEYKKKNRVMAMCDYCKLQKIIKETVRFSGVDKPFCSEVCKFLSARDFGERWGSYCKMCSYCSQTSPNLVENRLEGKLEEFCCEDCMTKFTVLFYQMAKCDGCKRQGKLSESIKWRGNIKHFCNLFCVLEFCHRQQIMNDPFSQNKVNISKAHIASVALPAARTNTTPVITNVVSLAKISPAQPTGSGVSKGAVVTKEATKIIENGSVQTDAMKLLSSQSSKLLKNKALLCKPVTQTKATSCKPHTQHKECQTDLSMPNEKNDVELDSPPAKKKRIGFFQTYDAEYLKVGFIICPGSKESSPRPQCVICGEILSSENMKPANLSHHLKTKHSELENKPVDFFEEKSLEMECQNSALKKCLLVEKSLVKASYLIAFQIAASKKPFSIAEELIKPYLVEMCSEVLGSSAGDKMKTIPLSNNTIGHRIDELSADIEDQLIQKVRESKWFALQIDESSEISNTTLLLCYIRFIDYGCSDIKEELLCCIEIPCQMTGFEIFELINKYIDSKSLNWKHCVGLCTDGAASMTGRCSGLRAKIQEVATNTVAFTHCFIHREHLAAAKLSPCLHEILLQSAQILSFIKSNALNSRMLTILCEEMGSEHVNLPLHAEVRWISRGRILTRLFELRHEIEIFLNQKHSDLAKYFFDEEWVAKVAYLSDIFSLINGLNLSLQGTMTTLFNLYNKIDVLKKKLKTWLKRTQENDYDMFPSFSDFSSSSGLNMSSMAGVILEHLEGLSQMLNDCYPPEDDVRSGNLWIINPFTNHQKSNLTDLEEEKLAQLSSDLRLQSVFKSMSVTQFWINAKASYPELHEKAMRFLLPFSTIYLCDATFSALTESKQRNLLVSGPALRLAVTSLIPRIEKLVKEKE", "length": 1320, "header": "tr|A0A3Q1LKZ2-1|F1MF92_BOVIN Computationally mapped isoform of Zinc finger MYM-type containing 4 OS=Bos taurus OX=9913 GN=ZMYM6 PE=4 SV=1 CANONICAL=F1MF92-1" }, "locus": { "chromosome": "3", "start_pos": 110693252, "end_pos": 110649609, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070872.2", "url": "https://www.ensembl.org/id/ENSBTAT00000070872.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057417.1", "url": "https://www.ensembl.org/id/ENSBTAP00000057417.1" } ] } }, { "isoform_ac": "A0A3Q1LY03-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LY03/entry", "sequence": { "sequence": "MDIPHFISSVSSGQILELLPSLSHCGGIMDTEMSEDIDHNLTPTLDSMSYGMPNQTGSENSLLDEDDYFLNSGDLAGIPVVGSDNEDEQDFSSKDNLVSSIHTDDSLEVERRVTQHESDNENEIQIQNKLKKDFPKQFDQVSVFKSIRKDFSLVRENSKETFSGKEKNRDLTYHEREKRLDKPHKELDSRLKSSFFDKAANQVEETLHTHLPQTPETNFRDSSYPFANKESIGSELGNSFASNIRIKEEPLDDEYDKAMAPQQGLLDRIKDEPDNAQEYSHGQQQKTQEGELKISAVFSVSGSPLAPQLTTGFQPSLASSGMNKMLPSVPATAVRVSCSGCKKILQKGQTAYQRKGSTQLFCSTLCLTGYTVPPARPPPPPTKKTCSSCSKDILNPKDVISAQFENTTTSKDFCSQSCLSTYELKRKPVVTINTNSISTKCSMCQKNAVIRHEVNYQNVVHKLCSDACFSKFRSANNLTMNCCENCGGYCYSGSGQCHMLQIEGQSKKFCSSTCVTAYKQKSAKITPCALCKSLRSSAEMIENTNSLGKTELFCSVNCLSAYRVKMVTSAGVQVQCNSCKTSAIPQYHLAMSDGSIRNFCSYSCVVAFQNLFNKPAGMNSSVVPLSQGQVIVSIPTGSTVSAGGGNTSAVSPTSISSSAAAGLQRLAAQSQHVGFARSVVKLKCQHCNRLFATKPELLDYKGKMFQFCGKNCSDEYKKINNVMAMCEYCKIEKIIKETVRFSGADKSFCSEGCKLLYKHDLAKRWGNHCKMCSYCLQTSPKLVQNNLGGKVEEFCCEECMSKYTVLLCQMAKCDGCKRQGKLSESLKWRGEMKHFCNLLCILMFCNQQSMCDPPSQNNAASISMVPAASAGPPSLRKDSTPVIANVVSLASAPAAQPTVNSNSVLQGAVPTVTAKIIGDASTQTDVLKLPPSQPPRLLKNKALLCKPITQTKATSCKPHTQNKECQTEDTPAQPQIIAVPVPVPVFVPVPLHLYTQYAPVPFGIPVPMPVPMLIPSSMGNEDKVTESIEDIKEKLPSHPFEADLLEMAEMIAEDEEKEKTLSQGESQTSEQELFLDTKIFEKDQGSTYSGDLESEAVSTPHSWEEELNHYALKSNTVQEADLEVKQFSKGETEQDLEADFPSESFDPLNKGQGIQVRSRTRRRHRDGFPQPRRRGRKKSIVSVEPRSLIQGAFQGCSVSGMTLKYMYGVNAWRNWVQWKNAKEEQGDLKCGGVEHASSSPCSDPLGSTQEHALSQESSEPGCKVRSIKLKEDILSCTFAELSLGLCQFIQEVRRPNGEKYDPDSILYLCLGIQQYLFENGRIDNIFTEPYSRFMIELTKLLKIWEPTILPNGYMFSRIEEEHLWECKQLGAYSPIVLLNTLLFFNTKYFQLRNVTEHLQLSFAHVMRRTRTLKYSTKMTYLRFFPPSQKQESEPDKLTIGKRKRNEDDDVPVGVEMAENTDNPLRCPVRLYEFYLSKCSESVKQRNDVFYLQPERSCVPNSPMWYSTFPIDPGTLDTMLTRILMVREVHEELAKAKSEDSDVELSD", "length": 1546, "header": "tr|A0A3Q1LY03-1|A0A3Q1LY03_BOVIN Computationally mapped isoform of Zinc finger MYM-type containing 4 OS=Bos taurus OX=9913 GN=ZMYM4 PE=4 SV=1 CANONICAL=F1MF92-1" }, "locus": { "chromosome": "3", "start_pos": 110424802, "end_pos": 110330493, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084859.2", "url": "https://www.ensembl.org/id/ENSBTAT00000084859.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062143.2", "url": "https://www.ensembl.org/id/ENSBTAP00000062143.2" } ] } }, { "isoform_ac": "F1MF92-1", "url": "https://www.uniprot.org/uniprotkb/F1MF92/entry", "sequence": { "sequence": "MAEREVESGPRKRVGEFEQKTGAVFDEIVENCGGIMDTEMSEDIDHNLTPTLDSMSYGMPNQTGSENSLLDEDDYFLNSGDLAGIPVVGSDNEDEQDFSSKDNLVSSIHTDDSLEVERRVTQHESDNENEIQIQNKLKKDFPKQFDQVSVFKSIRKDFSLVRENSKETFSGKEKNRDLTYHEREKRLDKPHKELDSRLKSSFFDKAANQVEETLHTHLPQTPETNFRDSSYPFANKESIGSELGNSFASNIRIKEEPLDDEYDKAMAPQQGLLDRIKDEPDNAQEYSHGQQQKTQEGELKISAVFSVSGSPLAPQLTTGFQPSLASSGMNKMLPSVPATAVRVSCSGCKKILQKGQTAYQRKGSTQLFCSTLCLTGYTVPPARPPPPPTKKTCSSCSKDILNPKDVISAQFENTTTSKDFCSQSCLSTYELKRKPVVTINTNSISTKCSMCQKNAVIRHEVNYQNVVHKLCSDACFSKFRSANNLTMNCCENCGGYCYSGSGQCHMLQIEGQSKKFCSSTCVTAYKQKSAKITPCALCKSLRSSAEMIENTNSLGKTELFCSVNCLSAYRVKMVTSAGVQVQCNSCKTSAIPQYHLAMSDGSIRNFCSYSCVVAFQNLFNKPAGMNSSVVPLSQGQVIVSIPTGSTVSAGGGNTSAVSPTSISSSAAAGLQRLAAQSQHVGFARSVVKLKCQHCNRLFATKPELLDYKGKMFQFCGKNCSDEYKKINNVMAMCEYCKIEKIIKETVRFSGADKSFCSEGCKLLYKHDLAKRWGNHCKMCSYCLQTSPKLVQNNLGGKVEEFCCEECMSKYTVLLCQMAKCDGCKRQGKLSESLKWRGEMKHFCNLLCILMFCNQQSMCDPPSQNNAASISMVPAASAGPPSLRKDSTPVIANVVSLASAPAAQPTVNSNSVLQGAVPTVTAKIIGDASTQTDVLKLPPSQPPRLLKNKALLCKPITQTKATSCKPHTQNKECQTEDTPAQPQIIAVPVPVPVFVPVPLHLYTQYAPVPFGIPVPMPVPMLIPSSMGNEDKVTESIEDIKEKLPSHPFEADLLEMAEMIAEDEEKEKTLSQGESQTSEQELFLDTKIFEKDQGSTYSGDLESEAVSTPHSWEEELNHYALKSNTVQEADLEVKQFSKGETEQDLEADFPSESFDPLNKGQGIQVRSRTRRRHRDGFPQPRRRGRKKSIVSVEPRSLIQGAFQGCSVSGMTLKYMYGVNAWRNWVQWKNAKEEQGDLKCGGVEHASSSPCSDPLGSTQEHALSQESSEPGCKVRSIKLKEDILSCTFAELSLGLCQFIQEVRRPNGEKYDPDSILYLCLGIQQYLFENGRIDNIFTEPYSRFMIELTKLLKIWEPTILPNGYMFSRIEEEHLWECKQLGAYSPIVLLNTLLFFNTKYFQLRNVTEHLQLSFAHVMRRTRTLKYSTKMTYLRFFPPSQKQESEPDKLTIGKRKRNEDDDVPVGVEMAENTDNPLRCPVRLYEFYLSKCSESVKQRNDVFYLQPERSCVPNSPMWYSTFPIDPGTLDTMLTRILMVREVHEELAKAKSEDSDVELSD", "length": 1553, "header": "tr|F1MF92-1|F1MF92_BOVIN Isoform 1 of Zinc finger MYM-type containing 4 OS=Bos taurus OX=9913 GN=ZMYM6 PE=4 SV=4 CANONICAL=F1MF92-1" }, "locus": { "chromosome": "3", "start_pos": 110491162, "end_pos": 110330493, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000029263.7", "url": "https://www.ensembl.org/id/ENSBTAT00000029263.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000029263.7", "url": "https://www.ensembl.org/id/ENSBTAP00000029263.7" } ] } }, { "isoform_ac": "F1MHR5-1", "url": "https://www.uniprot.org/uniprotkb/F1MHR5/entry", "sequence": { "sequence": "MLNIVPCAVQQFEQKTGAVFDEIVENCGGIMDTEMSEDIDHNLTPTLDSMSYGMPNQTGSENSLLDEDDYFLNSGDLAGIPVVGSDNEDEQDFSSKDNLVSSIHTDDSLEVERRVTQHESDNENEIQIQNKLKKDFPKQFDQVSVFKSIRKDFSLVRENSKETFSGKEKNRDLTYHEREKRLDKPHKELDSRLKSSFFDKAANQVEETLHTHLPQTPETNFRDSSYPFANKESIGSELGNSFASNIRIKEEPLDDEYDKAMAPQQGLLDRIKDEPDNAQEYSHGQQQKTQEGELKISAVFSVSGSPLAPQLTTGFQPSLASSGMNKMLPSVPATAVRVSCSGCKKILQKGQTAYQRKGSTQLFCSTLCLTGYTVPPARPPPPPTKKTCSSCSKDILNPKDVISAQFENTTTSKDFCSQSCLSTYELKRKPVVTINTNSISTKCSMCQKNAVIRHEVNYQNVVHKLCSDACFSKFRSANNLTMNCCENCGGYCYSGSGQCHMLQIEGQSKKFCSSTCVTAYKQKSAKITPCALCKSLRSSAEMIENTNSLGKTELFCSVNCLSAYRVKMVTSAGVQVQCNSCKTSAIPQYHLAMSDGSIRNFCSYSCVVAFQNLFNKPAGMNSSVVPLSQGQVIVSIPTGSTVSAGGGNTSAVSPTSISSSAAAGLQRLAAQSQHVGFARSVVKLKCQHCNRLFATKPELLDYKGKMFQFCGKNCSDEYKKINNVMAMCEYCKIEKIIKETVRFSGADKSFCSEGCKLLYKHDLAKRWGNHCKMCSYCLQTSPKLVQNNLGGKVEEFCCEECMSKYTVLLCQMAKCDGCKRQGKLSESLKWRGEMKHFCNLLCILMFCNQQSMCDPPSQNNAASISMVPAASAGPPSLRKDSTPVIANVVSLASAPAAQPTVNSNSVLQGAVPTVTAKIIGDASTQTDVLKLPPSQPPRLLKNKALLCKPITQTKATSCKPHTQNKECQTEDTPAQPQIIAVPVPVPVFVPVPLHLYTQYAPVPFGIPVPMPVPMLIPSSMGNEDKVTESIEDIKEKLPSHPFEADLLEMAEMIAEDEEKEKTLSQGESQTSEQELFLDTKIFEKDQGSTYSGDLESEAVSTPHSWEEELNHYALKSNTVQEADLEVKQFSKGETEQDLEADFPSESFDPLNKGQGIQVRSRTRRRHRDGFPQPRRRGRKKSIVSVEPRSLIQGAFQGCSVSGMTLKYMYGVNAWRNWVQWKNAKEEQGDLKCGGVEHASSSPCSDPLGSTQEHALSQESSEPGCKVRSIKLKEDILSCTFAELSLGLCQFIQEVRRPNGEKYDPDSILYLCLGIQQYLFENGRIDNIFTEPYSRFMIELTKLLKIWEPTILPNGYMFSRIEEEHLWECKQLGAYSPIVLLNTLLFFNTKYFQLRNVTEHLQLSFAHVMRRTRTLKYSTKMTYLRFFPPSQKQESEPDKLTIGKRKRNEDDDVPVGVEMAENTDNPLRCPVRLYEFYLSKCSESVKQRNDVFYLQPERSCVPNSPMWYSTFPIDPGTLDTMLTRILMVREVHEELAKAKSEDSDVELSD", "length": 1548, "header": "tr|F1MHR5-1|F1MHR5_BOVIN Computationally mapped isoform of Zinc finger MYM-type containing 4 OS=Bos taurus OX=9913 GN=ZMYM4 PE=4 SV=3 CANONICAL=F1MF92-1" }, "locus": { "chromosome": "3", "start_pos": 110478550, "end_pos": 110330493, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027998.7", "url": "https://www.ensembl.org/id/ENSBTAT00000027998.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027998.7", "url": "https://www.ensembl.org/id/ENSBTAP00000027998.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:618234", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618234", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2N4R2-1", "protein_name": "Zinc finger MYM-type protein 6 isoform X1", "gene_name": "Zmym6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKEPLDGECDKAMAQHGLLDKIKEEPDNAQEYGLQESELKISAVFSANDTSLGFQLGPLSPGSNTSFPSVPAAHVFCSGCKKLLHKTGCAQLFCSKECIIRYSSAVCLSPQPKRTCTHCSKDILNPMDVITTKVEDASSCKDFCSQLCLSSYELKKPVVTVYTSGVSTKCRMCQKVTDNLSQKPLYALGNSLKPFAEVNEITNDPGKTELFCSINCLSAYRIKTVISSGLQVLCHSCKTAAVPQYHVAMSDGTICSFCSSNCVLAFQNVFNKPEGTNSSLAPVSLGQEVINTPLQSTVSEGKGAPVSSFSGPISRPAADALETLAKQSQQIALTHSFMRLKCQHCNHLFARKPELLFYKGRMFLFCGKVCSEEYKRKNKVMALCDYCKIYKIIKDIVRFSGVDKPFCSEVCKSLSAQDFAERWANCCKMCSYCLQTSANFVESRLEGRLQVFCGEECMTKFTALFYQTAKCDGCKRQGKLSESLKWRGNIKYFCNLFCVLKFCHHYSVNDPVHKKVLLLPKSVSVIIPKAQTALTALPSPRIATTPVITSVISLAKLPALQPTKNVNSDLTGAGPKEAAKIIGNGNALADAERLQSLPPPMLQKNKGILCRPVTQTKATSCRPHTHHVECQTDFPLQNEKNEEPDSPPAKKKRMDFFQTYDAEYIKFGFIICSGSKESSPRAQCVICGEILPRESVMPVSLSNHLKAKHSELENKPVDFFEEKSLEMECQDSPLNKCLLVEESLVKASYLIAFQIAARKKPFSIAEELIKPYLVEMCSEVLGSSAGDKMKTIPLSNNTIECRINTLSADIEDQLVQKLRDSRWFALQIDESPETSDVTLLLCYVRFIDYDCDDVKEEFLFCTEMPSPSTDLQVFELISKYIDSRSLNWNHCVGFCTDGAASMTDRRSCLKSKIQEITKNTVVFTHCFIHREHLAAEKLSPGLHEILLQSAQILSFVKNSASDSKMLTVLCEEMGSELVNLPLSAELRWLSRGRILTRLFELRQEIEILLNQKHSDLARYFHDKEWVAKLAYLADMFSLINKLNSGLQGTMATLFNLYNKVDIFKRKLKAWLKRTQENDYDMFPLFSEFLDSSGVSVESITSMIVEHLQGLSQIFHDCYPPEEDLRLGNLWLIDPFASHQNNNLTDSEEEKLAALSSDTSLRSAYKSMSVTQFWVRAKTSHPELHEKAVKLLLPFSTFCLCDATFSALTASKQRNLLGFGPALRLAVTSLVPRIEKLVKEKE", "length": 1241 }, "evidence": [ { "id": "F1MF92", "url": "https://omabrowser.org/oma/group/F1MF92/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4AEF5-1", "protein_name": "Zinc finger MYM-type containing 6", "gene_name": "Zmym6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKEPLDGGCDKAMAQQGLLDRIKEEPDDAHEYGPQESELKISAVFSASDTSLGFQVGLPSPGLSASFPAVPAAQVFCFGCKQLLRKGQPTYRKAGSAQLFCSMGCVITFSSAVCVPPLPKRTCAHCSKDILNPMDVITTQFENSSLCKEFCSQSCLFSYELKKPVVTIYTSGISAKCSMCQKGTDNLAPKPLYALGNSSRLSAEMIETTNDSGRTELFCSINCLSAYRIKTVISSGIQVLCHSCKTAAVPQYHLAMSNGTICSFCSSNCVLAFQNVFNKPKGRNSSLAPISQGQEVLSAPMQSAVSARKEAPAPSFSSPISNPAAAALETLAKESHQIALTLSFLKLTCLQCSLLFATKPELLFYKGRMFMFCGKACCDEYKRQNKVKALCDYCKLQKTIEDTVRFSGVDKPFCSEVCKVLSARDFGERWGNYCKTCSYCLQTSANFVENQLEGKLQVFCCEDCMSKFTALLYQTARCDACKRQGKLSESLKWRGNIKYFCNLFCVLKFCHQYSANDPIPQRKVFVLPKPAQVIIPKVQTAMTALPSPKIATTPVITSVTSLAKIPALQPSRNTNSVCTDAGPTEATKIIGNGSKPAAAERLQSPQAPKLLKNKGILCKPVTQTKATSCRPHTHHVACQTDSPLPDGKNEEYDSPPAKRRRVDFFHTCNADYIKFGFIICSGSKESSPSPQCVICGEILPSESVMPVSLSNHLKAKHSDLENKPIDFFEEKSLEMECQNSSLKKCLLVEESLVKASYLIAFQIAARNKPFSIAEELIKPYLVEMCSEVLGSSAGDKMKTIPLSNSTIGCRIKKLSEDIEDQLLQKVRESRWFALQVDESSEVTDVPLLLCYVRFVDYDCGDVKEELLFCTEMPSPSTDLKVFELINQYIDSRSLHWNHCVGFCTDGAASLTDECSHLRSKIQEIAKNTVTFTHCFIHREHLAAEKLSPCLHEILLQLSQILSFVKNSASDSRMLTILCEEVGSGHVSLPLSAEVRWLARGRILTRLFELRHEIEIFLNQKHSDLARYFHDEEWVAKLAYLADIFSLINKLNSSLQGTMTTFFSLYNKVEIFKKRLKMWLKRAQENDYDMFPLFSEFLDSSDVSVRNIASIICEHLEGLSQVFHDCYPPEKDLRSGNLWLLNPFASYQDNNLTDSEEENLAALSSDTRFQSVHKSMSVTQFWVNAKTSYPELHEKAMKLLLPFSSTCLCDAAFSALTASKQRDLRTYSPSLRLAVTSLVPRIDKLAKEKD", "length": 1249 }, "evidence": [ { "id": "F1MF92", "url": "https://omabrowser.org/oma/group/F1MF92/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O95789-3", "protein_name": "Zinc finger MYM-type protein 6", "gene_name": "ZMYM6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKEPLDGECGKAVVPQQELLDKIKEEPDNAQEYGCVQQPKTQESKLKIGGVSSVNERPIAQQLNPGFQLSFASSGPSVLLPSVPAVAIKVFCSGCKKMLYKGQTAYHKTGSTQLFCSTRCITRHSSPACLPPPPKKTCTNCSKDILNPKDVITTRFENSYPSKDFCSQSCLSSYELKKKPVVTIYTKSISTKCSMCQKNADTRFEVKYQNVVHGLCSDACFSKFHSTNNLTMNCCENCGSYCYSSSGPCQSQKVFSSTSVTAYKQNSAQIPPYALGKSLRPSAEMIETTNDSGKTELFCSINCLSAYRVKTVTSSGVQVSCHSCKTSAIPQYHLAMSNGTIYSFCSSSCVVAFQNVFSKPKGTNSSAVPLSQGQVVVSPPSSRSAVSIGGGNTSAVSPSSIRGSAAASLQPLAEQSQQVALTHTVVKLKCQHCNHLFATKPELLFYKGKMFLFCGKNCSDEYKKKNKVVAMCDYCKLQKIIKETVRFSGVDKPFCSEVCKFLSARDFGERWGNYCKMCSYCSQTSPNLVENRLEGKLEEFCCEDCMSKFTVLFYQMAKCDGCKRQGKLSESIKWRGNIKHFCNLFCVLEFCHQQIMNDCLPQNKVNISKAKTAVTELPSARTDTTPVITSVMSLAKIPATLSTGNTNSVLKGAVTKEAAKIIQDESTQEDAMKFPSSQSSQPSRLLKNKGISCKPVTQTKATSCKPHTQHKECQTDLPMPNEKNDAELDSPPSKKKRLGFFQTYDTEYLKVGFIICPGSKESSPRPQCVICGEILSSENMKPANLSHHLKTKHSELENKPVDFFEQKSLEMECQNSSLKKCLLVEKSLVKASYLIAFQTAASKKPFSIAEELIKPYLVEMCSEVLGSSAGDKMKTIPLSNVTIQHRIDELSADIEDQLIQKVRESKWFALQIDESSEISNITLLLCYIRFIDYDCRDVKEELLFCIEMPTQITGFEIFELINKYIDSKSLNWKHCVGLCTDGAASMTGRYSGLKAKIQEVAMNTAAFTHCFIHRERLVAEKLSPCLHKILLQSAQILSFIKSNALNSRMLTILCEEMGSEHVSLPLHAEVRWISRGRMLKRLFELRHEIEIFLSQKHSDLAKYFHDEEWVGKLAYLSDIFSLINELNLSLQGTLTTFFNLCNKIDVFKRKLKMWLKRTQENDYDMFPSFSEFSNSSGLNMTDITRIIFEHLEGLSQVFSDCFPPEQDLRSGNLWIIHPFMNHQNNNLTDFEEEKLTELSSDLGLQALFKSVSVTQFWINAKTSYPELHERAMKFLLPFSTVYLCDAAFSALTESKQKNLLGSGPALRLAVTSLIPRIEKLVKEKE", "length": 1325 }, "evidence": [ { "id": "F1MF92", "url": "https://omabrowser.org/oma/group/F1MF92/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1MF92", "url": "https://www.uniprot.org/uniprotkb/F1MF92" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1MF92", "url": "https://www.uniprot.org/uniprotkb/F1MF92" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1400, "end_pos": 1402, "annotation": "n_glycosylation_sequon" }, { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" }, { "start_pos": 484, "end_pos": 486, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" }, { "start_pos": 626, "end_pos": 628, "annotation": "n_glycosylation_sequon" }, { "start_pos": 653, "end_pos": 655, "annotation": "n_glycosylation_sequon" }, { "start_pos": 718, "end_pos": 720, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1MF92-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1553, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1MF92-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1MF92" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1MF92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF92" }, { "id": "SM00746", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00746" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TRASH", "eco_id": "ECO_0000259", "start_pos": 345, "end_pos": 381, "start_aa": "Cys", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1400, "end_pos": 1402 }, { "start_pos": 413, "end_pos": 415 }, { "start_pos": 47, "end_pos": 49 }, { "start_pos": 484, "end_pos": 486 }, { "start_pos": 61, "end_pos": 63 }, { "start_pos": 626, "end_pos": 628 }, { "start_pos": 653, "end_pos": 655 }, { "start_pos": 718, "end_pos": 720 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1MET1-1", "uniprot_ac": "F1MET1", "uniprot_id": "F1MET1_BOVIN", "mass": { "chemical_mass": 38276.0, "monoisotopic_mass": 38276.0 }, "refseq": { "ac": "NP_001039690", "name": "membrane progestin receptor delta", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039690" }, "gene_names": [ { "name": "PAQR6", "type": "recommended", "evidence": [ { "id": "F1MET1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MET1" } ] }, { "name": "PAQR6", "type": "synonym", "evidence": [ { "id": "NP_001039690", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039690" } ] } ], "protein_names": [ { "name": "Progestin and adipoQ receptor family member 6", "type": "synonym", "evidence": [ { "id": "F1MET1", "database": 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"https://www.uniprot.org/uniprotkb/A0A3Q1LL02/entry", "sequence": { "sequence": "MDQSLSMGELSSPRSTWRCRATMLSLKLPQLLRVHQVPRVFWEDGIMSGYRRPTSSALDCVLSSFQMTNETVNIWTHFLPTWYFLWRLLALAAGLGFRSEPYHWPLLVFLLPACLYPFASCCAHTFSSMSPRVRHICYFLDYGALSLYSLGCAFPYAAYSMPASWLHSRLHQLFVPAAALNSFLCTGLSCYSRFPELESPGLSKILRSAAFIYPFLFDNLPLFYRLGLCWGRGRSCGQEALSTSHGYHLFCALLTGFLFASHLPERLAPGRFDYIGHSHQLFHICAVLGTHFQLEAVLTDMGSRRAWLATQEPPLGLAGTVATLGLAVAGNLLIIAAFTASLFRAPSTCTLLQGGSLERGTKAKLQ", "length": 366, "header": "tr|A0A3Q1LL02-1|F1MET1_BOVIN Computationally mapped isoform of Progestin and adipoQ receptor family member 6 OS=Bos taurus OX=9913 GN=PAQR6 PE=3 SV=1 CANONICAL=F1MET1-1" }, "locus": { "chromosome": "3", "start_pos": 14550390, "end_pos": 14547497, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081487.3", "url": "https://www.ensembl.org/id/ENSBTAT00000081487.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060413.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060413.2" } ] } }, { "isoform_ac": "F1MET1-1", "url": "https://www.uniprot.org/uniprotkb/F1MET1/entry", "sequence": { "sequence": "MLSLKLPQLLRVHQVPRVFWEDGIMSGYRRPTSSALDCVLSSFQMTNETVNIWTHFLPTWYFLWRLLALAAGLGFRSEPYHWPLLVFLLPACLYPFASCCAHTFSSMSPRVRHICYFLDYGALSLYSLGCAFPYAAYSMPASWLHSRLHQLFVPAAALNSFLCTGLSCYSRFPELESPGLSKILRSAAFIYPFLFDNLPLFYRLGLCWGRGRSCGQEALSTSHGYHLFCALLTGFLFASHLPERLAPGRFDYIGHSHQLFHICAVLGTHFQLEAVLTDMGSRRAWLATQEPPLGLAGTVATLGLAVAGNLLIIAAFTASLFRAPSTCTLLQGGSLERGTKAKLQ", "length": 344, "header": "tr|F1MET1-1|F1MET1_BOVIN Isoform 1 of Progestin and adipoQ receptor family member 6 OS=Bos taurus OX=9913 GN=PAQR6 PE=3 SV=3 CANONICAL=F1MET1-1" }, "locus": { "chromosome": "3", "start_pos": 14550390, "end_pos": 14547778, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012414.8", "url": "https://www.ensembl.org/id/ENSBTAT00000012414.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012414.6", "url": "https://www.ensembl.org/id/ENSBTAP00000012414.6" } ] } } ], 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"Rat" }, { "uniprot_canonical_ac": "A0A8M6YTQ0-1", "protein_name": "Membrane progestin receptor delta isoform X1", "gene_name": "paqr6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKKVTLFPAWRGAGEGHGWGWAQCVRWEAGEGGPSRGLECPLWCVLCRGGRDRLKQACQIGRGALRLPTDMLSLRLPQLFDIHQVPKVFREDGIMSGYRHPRSSALDCILSSFQMTNETVNIWTHFLPTWYFLWRFSVLCSSLDFVTDSYTWPLLVYMLLICLYPFTSSCAHTFSTMSAEARHICYFFDYGALSLYSLGCAISYGSYAMPDSWVNSWLHQHFVTIGICNSLFCTSMSCYTRFIELQFPHKSKILRTSAFVVPFLFDSFPLFYRLLSCCWGSCSPSEALASHSYHLLFAFLTCFLFASHLPERLAPGRFDYIGHSHQLFHICAVVGTHFQMEAALSDMASRKDWLISYSGLPTFQGTMGALALGVLLNLAIIGVFSASLIQTPRQSTSHPHQE", "length": 402 }, "evidence": [ { "id": "F1MET1", "url": "https://omabrowser.org/oma/group/F1MET1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6TCG5-1", "protein_name": "Membrane progestin receptor delta", "gene_name": "Paqr6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSLKMPQLLRVHQVPRVFWEEGIMSGYRCPTSSALDCVLSSFQMTNETVNIWTHFLPTWYFLWRLLALGSPGFRADPYHLPLLVFLLPACLYPFASCCAHTFSSMSPRARHICYFLDYGALSLYSLGCAFPYAAYSMPASWLHSRLHQLFVPAAALNSFLCTGLSCYSRFPELEYPGFSKALRTAAFAYPFLFDNLPLFYRLRLCWGGAHSCGRDALSSNHGYHLLCALLSGFLFAARLPERLAPGRFDYIGHSHQLFHICAVLGTHFQLEAVLADMGSRRAWLAVQEPTLGLGATVATLSLAVIGNLFIIAAFTASLLRMPGPCPLLQGSPLEEGLQAKQQ", "length": 343 }, "evidence": [ { "id": "F1MET1", "url": "https://omabrowser.org/oma/group/F1MET1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6TCH4-1", "protein_name": "Membrane progestin receptor delta", "gene_name": "PAQR6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSLKLPQLLQVHQVPRVFWEDGIMSGYRRPTSSALDCVLSSFQMTNETVNIWTHFLPTWYFLWRLLALAGGPGFRAEPYHWPLLVFLLPACLYPFASCCAHTFSSMSPRMRHICYFLDYGALSLYSLGCAFPYAAYSMPASWLHGHLHQFFVPAAALNSFLCTGLSCYSRFLELESPGLSKVLRTGAFAYPFLFDNLPLFYRLGLCWGRGHGCGQEALSTSHGYHLFCALLTGFLFASHLPERLAPGRFDYIGHSHQLFHICAVLGTHFQLEAVLADMGSRRAWLATQEPALGLAGTVATLVLAAAGNLLIIAAFTATLLRAPSTCPLLQGGPLEGGTQAKQQ", "length": 344 }, "evidence": [ { "id": "F1MET1", "url": "https://omabrowser.org/oma/group/F1MET1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1MET1", "url": "https://www.uniprot.org/uniprotkb/F1MET1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1MET1", "url": "https://www.uniprot.org/uniprotkb/F1MET1" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "F1MET1", "url": "https://www.uniprot.org/uniprotkb/F1MET1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1MET1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 344, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1MET1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1MET1" } ], 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1MG25-1", "uniprot_ac": "F1MG25", "uniprot_id": "F1MG25_BOVIN", "mass": { "chemical_mass": 244933.0, "monoisotopic_mass": 244933.0 }, "refseq": { "ac": "XP_010800301", "name": "bromodomain adjacent to zinc finger domain protein 2B isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010800301" }, "gene_names": [ { "name": "BAZ2B", "type": "recommended", "evidence": [ { "id": "F1MG25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG25" } ] }, { "name": "BAZ2B", "type": "synonym", "evidence": [ { "id": "XP_010800301", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010800301" } ] } ], "protein_names": [ { "name": "Bromodomain adjacent to zinc finger domain protein 2B", "type": "recommended", "evidence": [ { "id": "F1MG25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG25/entry#names_and_taxonomy" } ] }, { "name": "bromodomain adjacent to zinc finger domain protein 2B isoform X2", "type": "synonym", "evidence": [ { "id": "XP_010800301", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010800301" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1MG25", "url": "https://www.uniprot.org/uniprotkb/F1MG25" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "BAZ2B", "url": "https://www.uniprot.org/uniprotkb/F1MG25", "locus": { "chromosome": "2", "start_pos": 37045806, "end_pos": 36715262, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020654", "url": "https://www.ensembl.org/id/ENSBTAG00000020654" } ] } } ], "crossref": [ { "id": "F1MG25", "url": "https://alphafold.ebi.ac.uk/entry/F1MG25", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020654", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020654", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01397", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01397", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05503", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05503", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15630", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15630", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "535498", "url": "https://www.ncbi.nlm.nih.gov/gene/535498", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001487", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001487", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001739", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001739", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016177", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016177", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018501", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018501", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028941", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028941", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037374", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037374", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LLX5", "url": "https://www.orthodb.org/?gene=A0A3Q1LLX5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BNJ5", "url": "https://www.orthodb.org/?gene=E1BNJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MCP3", "url": "https://www.orthodb.org/?gene=F1MCP3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MG25", "url": "https://www.orthodb.org/?gene=F1MG25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45915", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45915", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45915:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45915:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00439", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00439", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01429", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01429", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02791", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02791", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15613", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15613", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010800301", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010800301", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LLX5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LLX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T048", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T048", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T048-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T048-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TEY1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TEY1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNJ5", "url": "https://www.uniprot.org/uniprotkb/E1BNJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNJ5-1", "url": "https://www.uniprot.org/uniprotkb/E1BNJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MCP3", "url": "https://www.uniprot.org/uniprotkb/F1MCP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MCP3-1", "url": "https://www.uniprot.org/uniprotkb/F1MCP3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MG25", "url": "https://www.uniprot.org/uniprotkb/F1MG25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MG25-1", "url": "https://www.uniprot.org/uniprotkb/F1MG25-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESGERLPSSTASSATPTSSSIPSVASSVSKGGLSTGAASLSSTINPCGHLFRAAGDQPFNLSTVSSAFPMVSHPVFGLHSASSGHSEFGGLGTLGTPTALAAHPQLASFPGAEWWRTTDVHTRAGAAFFPPLLGIPPLFAPPAQNHDSSSFHSRTSGKSNRNGPEKGVNGSINGNSTSSVSGINTSVLSTTASSSVGQTKSVSSGGGNRKCNQEQNKTQPLDARADKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEDQSIEESEDDDSDSETEAQQKSNNQVLLHGVSDPKAEGQKATEKAQEKRIHQPLPLLSESQTHSSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVSNVKPLSLVNQAKKETYMKLIVPSPDVLKAGNKNTSEESSSLTSELRSKREQYKQTFPAQLKKQESSKSLKKVIAALSNPKPTSSSPAHPKQTLENSNPNPFLTNALLGNHQPNGVIQSVIQEAPLALTTKTKMQSKINENIATASSTPFSSPVNLSTSGRRTPGSQTTVIPSPSPILHSQGKEKAVSNNVNTVKTQPHSHPAQSLVEQFRGTDSDILSSKDSEDSNEDEEEDDEEDEEDEEDDDSDDSQSESDSNSESDTEGSEEDDDDDKDQDESDSDTEGEKTSMKLNKTASSVKSPSISLTAHSTPRNLHIAKAPGSAPAALCSESQSPAFLGTPSSTLTSSPHSGTSKRRRVTDERELHIPLEYGWQRETRIRNFGGRLQGEVAYYAPCGKKLRQYPEVIKYLSRNGIMDISRDNFSFSAKIRVGDFYEARDGPQGMQWCLLKEEDVIPRIRAMEGRRGRPPNPDRQRAREESRIRRRKGRPPNVGSTEFLDNTDAKLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIIAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQELERHRLDMERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKLEQRRLELEMAKELKKPNEDMCLADQKPLPELPRIPGLVLSGSTFSDCLMVVQFLRNFGKVLGFDVNIDVPNLSVLQEGLLNIGDSMGEVQDLLVRLLSAAVCDPGLITGYKAKTALGEHLLNVGVNRDNVSEILQIFMEAHCGQTELTESLKTKAFQAHTPAQKASVLAFLINELACSKSVVSEIDKNIDYMSNLRRDKWVVEGKLRKLRIIHAKKTGKRDTSGGIDLGEEQHPLGTPTPGRKRRRKGGDSDYDDDDDDDSDDQADEDDEDEEDKEDKKGKKTEICEDEDEGDQAASVEELEKQIEKLSKQQSQYRRKLFDASHSLRSMMFGQDRYRRRYWILPQCGGIFVEGMESGEGLEEIAKEREKLKKAKSIQIKEEIFETSEHTLNCSNPDHCEQKEDTKEKDNPNLFLQKPGSFSKLSKLLEVAKMPAESDVMTPKPNSSANGCTLSYQNSGKQSLGSIQSTATQSNTEKTDSNNLFSTSSSGPGKFYSPLPNDQLLKTLTEKNRQWFSLLPRTPCDDTSLTHASMSTASSVTPQSQPLSKSPSPAPAPLLGSSAQNPVGLNPFALSPLQVKSGVSVMGLQFCGWPAGVLTSNIPFTSPLPNLGSGLGLSEGNSNTFVTPNVAPSKSESPVPQNEKVSSTQPAAVEVAKPVDFPSPKPIPEEMQFGWWRIIDPEDLKALLKVLHLRGIREKALQKQIQKHLDYITQACIKNKDVAIIELNENEENQVTRDIVENWSIEEQAMEMDLNILQQVEDLERRVASASLQVKGWMCPEPASEREDLVYFEHKSFSKLCKEHDGEFTGEEEGSAHALERKSDNPLDIAVTRLADLERNIERRYLKSPLSTTIQIKLDNVGTVTVPAPAPSVSGDGDGIEEDIAPGLRVWRRALSEARSAAQVALCIQQLQKSIAWEKSIMKVYCQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACIAKASGQTLKIKKLHVKGKKSESKKGKKVTLTGDTEDEDSASTSSSLKRGVKDLKKRKMEENSSINISKQESFTSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHSMRKYFEKKWTDTFKVS", "length": 2211, "header": "tr|F1MG25-1|F1MG25_BOVIN Isoform 1 of Bromodomain adjacent to zinc finger domain protein 2B OS=Bos taurus OX=9913 GN=BAZ2B PE=3 SV=4 CANONICAL=F1MG25-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LLX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLX5/entry", "sequence": { "sequence": "MESGERLPSSTASSATPTSSSIPSVASSVSKGGLSTGAASLSSTINPCGHLFRAAGDQPFNLSTVSSAFPMVSHPVFGLHSASSGHSEFGGLGTLGTPTALAAHPQLASFPGAEWWRTTDVHTRAGAAFFPPLLGIPPLFAPPAQNHDSSSFHSRTSGKSNRNGPEKGVNGSINGNSTSSVSGINTSVLSTTASSSVGQTKSVSSGGGNRKCNQEQNKTQPLDARADKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEDQSIEESEDDDSDSETEAQQKSNNQVLLHGVSDPKAEGQKATEKAQEKRIHQPLPLLSESQTHSSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVSNVKPLSLVNQAKKETYMKLIVPSPDVLKAGNKNTSEESSSLTSELRSKREQYKQTFPAQLKKQESSKSLKKVIAALSNPKPTSSSPAHPKQTLENSNPNPFLTNALLGNHQPNGVIQSVIQEAPLALTTKTKMQSKINENIATASSTPFSSPVNLSTSGRRTPGSQTTVIPSPSPILHSQGKEKAVSNNVNTVKTQPHSHPAQSLVEQFRGTDSDILSSKDSEDSNEDEEEDDEEDEEDEEDDDSDDSQSESDSNSESDTEGSEEDDDDDKDQDESDSDTEGEKTSMKLNKTASSVKSPSISLTAHSTPRNLHIAKAPGSAPAALCSESQSPAFLGTPSSTLTSSPHSGTSKRRRVTDERELHIPLEYGWQRETRIRNFGGRLQGEVAYYAPCGKKLRQYPEVIKGMQWCLLKEEDVIPRIRAMEGRRGRPPNPDRQRAREESRIRRRKGRPPNVGSTEFLDNTDAKLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIIAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQELERHRLDMERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKLEQRRLELEMAKELKKPNEDMCLADQKPLPELPRIPGLVLSGSTFSDCLMVVQFLRNFGKVLGFDVNIDVPNLSVLQEGLLNIGDSMGEVQDLLVRLLSAAVCDPGLITGYKAKTALGEHLLNVGVNRDNVSEILQIFMEAHCGQTELTESLKTKAFQAHTPAQKASVLAFLINELACSKSVVSEIDKNIDYMSNLRRDKWVVEGKLRKLRIIHAKKTGKRDTSGGIDLGEEQHPLGTPTPGRKRRRKGGDSDYDDDDDDDSDDQADEDDEDEEDKEDKKGKKTEICEDEDEGDQAASVEELEKQIEKLSKQQSQYRRKLFDASHSLRSMMFGQDRYRRRYWILPQCGGIFVEGMESGEGLEEIAKEREKLKKAKSIQIKEEIFETSEHTLNCSNPDHCEQKEDTKEKDNPNLFLQKPGSFSKLSKLLEVAKMPAESDVMTPKPNSSANGCTLSYQNSGKQSLGSIQSTATQSNTEKTDSNNLFSTSSSGPGKFYSPLPNDQLLKTLTEKNRQWFSLLPRTPCDDTSLTHASMSTASSVTPQSQPLSKSPSPAPAPLLGSSAQNPVGLNPFALSPLQVKSGVSVMGLQFCGWPAGVLTSNIPFTSPLPNLGSGLGLSEGNSNTFVTPNVAPSKSESPVPQNEKVSSTQPAAVEVAKPVDFPSPKPIPEEMQFGWWRIIDPEDLKALLKVLHLRGIREKALQKQIQKHLDYITQACIKNKDVAIIELNENEENQVTRDIVENWSIEEQAMEMDLNILQQVEDLERRVASASLQVKGWMCPEPASEREDLVYFEHKSFSKLCKEHDGEFTGEEEGSAHALERKSDNPLDIAVTRLADLERNIERRYLKSPLSTTIQIKLDNVGTVTVPAPAPSVSGDGDGIEEDIAPGLRVWRRALSEARSAAQVALCIQQLQKSIAWEKSIMKVYCQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACIAKASGQTLKIKKLHVKGKKSESKKGKKVTLTGDTEDEDSASTSSSLKRGVKDLKKRKMEENSSINISKQESFTSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHSMRKYFEKKWTDTFKVS", "length": 2177, "header": "tr|A0A3Q1LLX5-1|F1MG25_BOVIN Computationally mapped isoform of Bromodomain adjacent to zinc finger domain protein 2B OS=Bos taurus OX=9913 GN=BAZ2B PE=3 SV=2 CANONICAL=F1MG25-1" }, "locus": { "chromosome": "2", "start_pos": 37045756, "end_pos": 36893457, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074575.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074575.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060837.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060837.2" } ] } }, { "isoform_ac": "A0AAA9T048-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T048/entry", "sequence": { "sequence": "MLYYMESGERLPSSTASSATPTSSSIPSVASSVSKGGLSTGAASLSSTINPCGHLFRAAGDQPFNLSTVSSAFPMVSHPVFGLHSASSGHSEFGGLGTLGTPTALAAHPQLASFPGAEWWRTTDVHTRAGAAFFPPLLGIPPLFAPPAQNHDSSSFHSRTSGKSNRNGPEKGVNGSINGNSTSSVSGINTSVLSTTASSSVGQTKSVSSGGGNRKCNQEQNKTQPLDARADKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEDQSIEESEDDDSDSETEAQQKSNNQVLLHGVSDPKAEGQKATEKAQEKRIHQPLPLLSESQTHSSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVSNVKPLSLVNQAKKETYMKLIVPSPDVLKAGNKNTSEESSSLTSELRSKREQYKQTFPAQLKKQESSKSLKKVIAALSNPKPTSSSPAHPKQTLENSNPNPFLTNALLGNHQPNGVIQSVIQEAPLALTTKTKMQSKINENIATASSTPFSSPVNLSTSGRRTPGSQTTVIPSPSPILHSQGKEKAVSNNVNTVKTQPHSHPAQSLVEQFRGTDSDILSSKDSEDSNEDEEEDDEEDEEDEEDDDSDDSQSGTSKRRRVTDERELHIPLEYGWQRETRIRNFGGRLQGEVAYYAPCGKKLRQYPEVIKGMQWCLLKEEDVIPRIRAMEGRRGRPPNPDRQRAREESRIRRRKGRPPNVGSTEFLDNTDAKLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIIAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKLEQRRLELEMAKELKKPNEDMCLADQKPLPELPRIPGLVLSGSTFSDCLMVVQFLRNFGKVLGFDVNIDVPNLSVLQEGLLNIGDSMGEVQDLLVRLLSAAVCDPGLITGYKAKTALGEHLLNVGVNRDNVSEILQIFMEAHCGQTELTESLKTKAFQAHTPAQKASVLAFLINELACSKSVVSEIDKNIDYMSNLRRDKWVVEGKLRKLRIIHAKKTGKRDTSGGIDLGEEQHPLGTPTPGRKRRRKGGDSDYDDDDDDDSDDQADEDDEDEEDKEDKKGKKTEICEDEDEGDQAASVEELEKQIEKLSKQQSQYRRKLFDASHSLRSMMFGQDRYRRRYWILPQCGGIFVEGMESGEGLEEIAKEREKLKKAKSIQIKEEIFETSEHTLNCSNPDHCEQKEDTKEKDNPNLFLQKPGSFSKLSKLLEVAKMPAESDVMTPKPNSSANGCTLSYQNSGKQSLGSIQSTATQSNTEKTDSNNLFSTSSSGPGKFYSPLPNDQLLKTLTEKNRQWFSLLPRTPCDDTSLTHASMSTASSVTPQSQPLSKSPSPAPAPLLGSSAQNPVGLNPFALSPLQVKSGVSVMGLQFCGWPAGVLTSNIPFTSPLPNLGSGLGLSEGNSNTFVTPNVAPSKSESPVPQNEKVSSTQPAAVEVAKPVDFPSPKPIPEEMQFGWWRIIDPEDLKALLKVLHLRGIREKALQKQIQKHLDYITQACIKNKDVAIIELNENEENQVTRDIVENWSIEEQAMEMDLNILQQVEDLERRVASASLQVKGWMCPEPASEREDLVYFEHKSFSKLCKEHDGEFTGEEEGSAHALERKSDNPLDIAVTRLADLERNIERRYLKSPLSTTIQIKLDNVGTVTVPAPAPSVSGDGDGIEEDIAPGLRVWRRALSEARSAAQVALCIQQLQKSIAWEKSIMKVYCQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACIAKASGQTLKIKKLHVKGKKSESKKGKKVTLTGDTEDEDSASTSSSLKRGVKDLKKRKMEENSSINISKQESFTSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHSMRKYFEKKWTDTFKVS", "length": 2074, "header": "tr|A0AAA9T048-1|A0AAA9T048_BOVIN Computationally mapped isoform of Bromodomain adjacent to zinc finger domain protein 2B OS=Bos taurus OX=9913 GN=BAZ2B PE=3 SV=1 CANONICAL=F1MG25-1" }, "locus": { "chromosome": "2", "start_pos": 37045756, "end_pos": 36846975, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000111854.1", "url": "https://www.ensembl.org/id/ENSBTAT00000111854.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091060.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091060.1" } ] } }, { "isoform_ac": "A0AAA9TEY1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEY1/entry", "sequence": { "sequence": "MESGERLPSSTASSATPTSSSIPSVASSVSKGGLSTGAASLSSTINPCGHLFRAAGDQPFNLSTVSSAFPMVSHPVFGLHSASSGHSEFGGLGTLGTPTALAAHPQLASFPGAEWWRTTDVHTRAGAAFFPPLLGIPPLFAPPAQNHDSSSFHSRTSGKSNRNGPEKGVNGSINGNSTSSVSGINTSVLSTTASSSVGQTKSVSSGGGNRKCNQEQNKTQPLDARADKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEDQSIEESEDDDSDSETEAQQKSNNQVLLHGVSDPKAEGQKATEKAQEKRIHQPLPLLSESQTHSSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVSNVKPLSLVNQAKKETYMKLIVPSPDVLKAGNKNTSEESSSLTSELRSKREQYKQTFPAQLKKQESSKSLKKVIAALSNPKPTSSSPAHPKQTLENSNPNPFLTNALLGNHQPNGVIQSVIQEAPLALTTKTKMQSKINENIATASSTPFSSPVNLSTSGRRTPGSQTTVIPSPSPILHSQGKEKAVSNNVNTVKTQPHSHPAQSLVEQFRGTDSDILSSKDSEDSNEDEEEDDEEDEEDEEDDDSDDSQSGTSKRRRVTDERELHIPLEYGWQRETRIRNFGGRLQGEVAYYAPCGKKLRQYPEVIKYLSRNGIMDISRDNFSFSAKIRVGDFYEARDGPQGMQWCLLKEEDVIPRIRAMEGRRGRPPNPDRQRAREESRIRRRKGRPPNVGSTEFLDNTDAKLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIIAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQELERHRLDMERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKLEQRRLELEMAKELKKPNEDMCLADQKPLPELPRIPGLVLSGSTFSDCLMVVQFLRNFGKVLGFDVNIDVPNLSVLQEGLLNIGDSMGEVQDLLVRLLSAAVCDPGLITGYKAKTALGEHLLNVGVNRDNVSEILQIFMEAHCGQTELTESLKTKAFQAHTPAQKASVLAFLINELACSKSVVSEIDKNIDYMSNLRRDKWVVEGKLRKLRIIHAKKTGKRDTSGGIDLGEEQHPLGTPTPGRKRRRKGGDSDYDDDDDDDSDDQADEDDEDEEDKEDKKGKKTEICEDEDEGDQAASVEELEKQIEKLSKQQSQYRRKLFDASHSLRSMMFGQDRYRRRYWILPQCGGIFVEGMESGEGLEEIAKEREKLKKAKSIQIKEEIFETSEHTLNCSNPDHCEQKEDTKEKDNPNLFLQKPGSFSKLSKLLEVAKMPAESDVMTPKPNSSANGCTLSYQNSGKQSLGSIQSTATQSNTEKTDSNNLFSTSSSGPGKFYSPLPNDQLLKTLTEKNRQWFSLLPRTPCDDTSLTHASMSTASSVTPQSQPLSKSPSPAPAPLLGSSAQNPVGLNPFALSPLQVKSGVSVMGLQFCGWPAGVLTSNIPFTSPLPNLGSGLGLSEGNSNTFVTPNVAPSKSESPVPQNEKVSSTQPAAVEVAKPVDFPSPKPIPEEMQFGWWRIIDPEDLKALLKVLHLRGIREKALQKQIQKHLDYITQACIKNKDVAIIELNENEENQVTRDIVENWSIEEQAMEMDLNILQQVEDLERRVASASLQVKGWMCPEPASEREDLVYFEHKSFSKLCKEHDGEFTGEEEGSAHALERKSDNPLDIAVTRLADLERNIERRYLKSPLSTTIQIKLDNVGTVTVPAPAPSVSGDGDGIEEDIAPGLRVWRRALSEARSAAQVALCIQQLQKSIAWEKSIMKVYCQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACIAKASGQTLKIKKLHVKGKKSESKKGKKVTLTGDTEDEDSASTSSSLKRGVKDLKKRKMEENSSINISKQESFTSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHSMRKYFEKKWTDTFKVS", "length": 2113, "header": "tr|A0AAA9TEY1-1|A0AAA9TEY1_BOVIN Computationally mapped isoform of Bromodomain adjacent to zinc finger domain protein 2B OS=Bos taurus OX=9913 GN=BAZ2B PE=3 SV=1 CANONICAL=F1MG25-1" }, "locus": { "chromosome": "2", "start_pos": 37045756, "end_pos": 36893457, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132754.1", "url": "https://www.ensembl.org/id/ENSBTAT00000132754.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095395.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095395.1" } ] } }, { "isoform_ac": "E1BNJ5-1", "url": "https://www.uniprot.org/uniprotkb/E1BNJ5/entry", "sequence": { "sequence": "MESGERLPSSTASSATPTSSSIPSVASSVSKGGLSTGAASLSSTINPCGHLFRAAGDQPFNLSTVSSAFPMVSHPVFGLHSASSGHSEFGGLGTLGTPTALAAHPQLASFPGAEWWRTTDVHTRAGAAFFPPLLGIPPLFAPPAQNHDSSSFHSRTSGKSNRNGPEKGVNGSINGNSTSSVSGINTSVLSTTASSSVGQTKSVSSGGGNRKCNQEQNKTQPLDARADKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEDQSIEESEDDDSDSETEAQQKSNNQVLLHGVSDPKAEGQKATEKAQEKRIHQPLPLLSESQTHSSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVSNVKPLSLVNQAKKETYMKLIVPSPDVLKAGNKNTSEESSSLTSELRSKREQYKQTFPAQLKKQESSKSLKKVIAALSNPKPTSSSPAHPKQTLENSNPNPFLTNALLGNHQPNGVIQSVIQEAPLALTTKTKMQSKINENIATASSTPFSSPVNLSTSGRRTPGSQTTVIPSPSPILHSQGKEKAVSNNVNTVKTQPHSHPAQSLVEQFRGTDSDILSSKDSEDSNEDEEEDDEEDEEDEEDDDSDDSQSESDSNSESDTEGSEEDDDDDKDQDESDSDTEGEKTSMKLNKTASSVKSPSISLTAHSTPRNLHIAKAPGSAPAALCSESQSPAFLGTPSSTLTSSPHSGTSKRRRVTDERELHIPLEYGWQRETRIRNFGGRLQGEVAYYAPCGKKLRQYPEVIKYLSRNGIMDISRDNFSFSAKIRVGDFYEARDGPQGMQWCLLKEEDVIPRIRAMEGRRGRPPNPDRQRAREESRIRRRKGRPPNVGSTEFLDNTDAKLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIIAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKLEQRRLELEMAKELKKPNEDMCLADQKPLPELPRIPGLVLSGSTFSDCLMVVQFLRNFGKVLGFDVNIDVPNLSVLQEGLLNIGDSMGEVQDLLVRLLSAAVCDPGLITGYKAKTALGEHLLNVGVNRDNVSEILQIFMEAHCGQTELTESLKTKAFQAHTPAQKASVLAFLINELACSKSVVSEIDKNIDYMSNLRRDKWVVEGKLRKLRIIHAKKTGKRDTSGGIDLGEEQHPLGTPTPGRKRRRKGGDSDYDDDDDDDSDDQADEDDEDEEDKEDKKGKKTEICEDEDEGDQAASVEELEKQIEKLSKQQSQYRRKLFDASHSLRSMMFGQDRYRRRYWILPQCGGIFVEGMESGEGLEEIAKEREKLKKAKSIQIKEEIFETSEHTLNCSNPDHCEQKEDTKEKDNPNLFLQKPGSFSKLSKLLEVAKMPAESDVMTPKPNSSANGCTLSYQNSGKQSLGSIQSTATQSNTEKTDSNNLFSTSSSGPGKFYSPLPNDQLLKTLTEKNRQWFSLLPRTPCDDTSLTHASMSTASSVTPQSQPLSKSPSPAPAPLLGSSAQNPVGLNPFALSPLQVKSGVSVMGLQFCGWPAGVLTSNIPFTSPLPNLGSGLGLSEGNSNTFVTPNVAPSKSESPVPQNEKVSSTQPAAVEVAKPVDFPSPKPIPEEMQFGWWRIIDPEDLKALLKVLHLRGIREKALQKQIQKHLDYITQACIKNKDVAIIELNENEENQVTRDIVENWSIEEQAMEMDLNILQQVEDLERRVASASLQVKGWMCPEPASEREDLVYFEHKSFSKLCKEHDGEFTGEEEGSAHALERKSDNPLDIAVTRLADLERNIERRYLKSPLSTTIQIKLDNVGTVTVPAPAPSVSGDGDGIEEDIAPGLRVWRRALSEARSAAQVALCIQQLQKSIAWEKSIMKVYCQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACIAKASGQTLKIKKLHVKGKKSESKKGKKVTLTGDTEDEDSASTSSSLKRGVKDLKKRKMEENSSINISKQESFTSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHSMRKYFEKKWTDTFKVS", "length": 2202, "header": "tr|E1BNJ5-1|E1BNJ5_BOVIN Computationally mapped isoform of Bromodomain adjacent to zinc finger domain protein 2B OS=Bos taurus OX=9913 GN=BAZ2B PE=3 SV=4 CANONICAL=F1MG25-1" }, "locus": { "chromosome": "2", "start_pos": 37045756, "end_pos": 36893457, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061234.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061234.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053510.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053510.4" } ] } }, { "isoform_ac": "F1MCP3-1", "url": "https://www.uniprot.org/uniprotkb/F1MCP3/entry", "sequence": { "sequence": "MESGERLPSSTASSATPTSSSIPSVASSVSKGGLSTGAASLSSTINPCGAEWWRTTDVHTRAGAAFFPPLLGIPPLFAPPAQNHDSSSFHSRTSGKSNRNGPEKGVNGSINGNSTSSVSGINTSVLSTTASSSVGQTKSVSSGGGNRKCNQEQNKTQPLDARADKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEDQSIEESEDDDSDSETEAQQKSNNQVLLHGVSDPKAEGQKATEKAQEKRIHQPLPLLSESQTHSSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVSNVKPLSLVNQAKKETYMKLIVPSPDVLKAGNKNTSEESSSLTSELRSKREQYKQTFPAQLKKQESSKSLKKVIAALSNPKPTSSSPAHPKQTLENSNPNPFLTNALLGNHQPNGVIQSVIQEAPLALTTKTKMQSKINENIATASSTPFSSPVNLSTSGRRTPGSQTTVIPSPSPILHSQGKEKAVSNNVNTVKTQPHSHPAQSLVEQFRGTDSDILSSKDSEDSNEDEEEDDEEDEEDEEDDDSDDSQSGTSKRRRVTDERELHIPLEYGWQRETRIRNFGGRLQGEVAYYAPCGKKLRQYPEVIKYLSRNGIMDISRDNFSFSAKIRVGDFYEARDGPQGMQWCLLKEEDVIPRIRAMEGRRGRPPNPDRQRAREESRIRRRKGRPPNVGSTEFLDNTDAKLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIIAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKLEQRRLELEMAKELKKPNEDMCLADQKPLPELPRIPGLVLSGSTFSDCLMVVQFLRNFGKVLGFDVNIDVPNLSVLQEGLLNIGDSMGEVQDLLVRLLSAAVCDPGLITGYKAKTALGEHLLNVGVNRDNVSEILQIFMEAHCGQTELTESLKTKAFQAHTPAQKASVLAFLINELACSKSVVSEIDKNIDYMSNLRRDKWVVEGKLRKLRIIHAKKTGKRDTSGGIDLGEEQHPLGTPTPGRKRRRKGGDSDYDDDDDDDSDDQADEDDEDEEDKEDKKGKKTEICEDEDEGDQAASVEELEKQIEKLSKQQSQYRRKLFDASHSLRSMMFGQDRYRRRYWILPQCGGIFVEGMESGEGLEEIAKEREKLKKAKSIQIKEEIFETSEHTLNCSNPDHCEQKEDTKEKDNPNLFLQKPGSFSKLSKLLEVAKMPAESDVMTPKPNSSANGCTLSYQNSGKQSLGSIQSTATQSNTEKTDSNNLFSTSSSGPGKFYSPLPNDQLLKTLTEKNRQWFSLLPRTPCDDTSLTHASMSTASSVTPQSQPLSKSPSPAPAPLLGSSAQNPVGLNPFALSPLQVKSGVSVMGLQFCGWPAGVLTSNIPFTSPLPNLGSGLGLSEGNSNTFVTPNVAPSKSESPVPQNEKVSSTQPAAVEVAKPVDFPSPKPIPEEMQFGWWRIIDPEDLKALLKVLHLRGIREKALQKQIQKHLDYITQACIKNKDVAIIELNENEENQVTRDIVENWSIEEQAMEMDLNILQQVEDLERRVASASLQVKGWMCPEPASEREDLVYFEHKSFSKLCKEHDGEFTGEEEGSAHALERKSDNPLDIAVTRLADLERNIERRYLKSPLSTTIQIKLDNVGTVTVPAPAPSVSGDGDGIEEDIAPGLRVWRRALSEARSAAQVALCIQQLQKSIAWEKSIMKVYCQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACIAKASGQTLKIKKLHVKGKKSESKKGKKVTLTGDTEDEDSASTSSSLKRGVKDLKKRKMEENSSINISKQESFTSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHSMRKYFEKKWTDTFKVS", "length": 2041, "header": "tr|F1MCP3-1|F1MCP3_BOVIN Computationally mapped isoform of Bromodomain adjacent to zinc finger domain protein 2B OS=Bos taurus OX=9913 GN=BAZ2B PE=3 SV=5 CANONICAL=F1MG25-1" }, "locus": { "chromosome": "2", "start_pos": 37045756, "end_pos": 36893457, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000046021.6", "url": "https://www.ensembl.org/id/ENSBTAT00000046021.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000043353.6", "url": "https://www.ensembl.org/id/ENSBTAP00000043353.6" } ] } }, { "isoform_ac": "F1MG25-1", "url": "https://www.uniprot.org/uniprotkb/F1MG25/entry", "sequence": { "sequence": "MESGERLPSSTASSATPTSSSIPSVASSVSKGGLSTGAASLSSTINPCGHLFRAAGDQPFNLSTVSSAFPMVSHPVFGLHSASSGHSEFGGLGTLGTPTALAAHPQLASFPGAEWWRTTDVHTRAGAAFFPPLLGIPPLFAPPAQNHDSSSFHSRTSGKSNRNGPEKGVNGSINGNSTSSVSGINTSVLSTTASSSVGQTKSVSSGGGNRKCNQEQNKTQPLDARADKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEDQSIEESEDDDSDSETEAQQKSNNQVLLHGVSDPKAEGQKATEKAQEKRIHQPLPLLSESQTHSSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVSNVKPLSLVNQAKKETYMKLIVPSPDVLKAGNKNTSEESSSLTSELRSKREQYKQTFPAQLKKQESSKSLKKVIAALSNPKPTSSSPAHPKQTLENSNPNPFLTNALLGNHQPNGVIQSVIQEAPLALTTKTKMQSKINENIATASSTPFSSPVNLSTSGRRTPGSQTTVIPSPSPILHSQGKEKAVSNNVNTVKTQPHSHPAQSLVEQFRGTDSDILSSKDSEDSNEDEEEDDEEDEEDEEDDDSDDSQSESDSNSESDTEGSEEDDDDDKDQDESDSDTEGEKTSMKLNKTASSVKSPSISLTAHSTPRNLHIAKAPGSAPAALCSESQSPAFLGTPSSTLTSSPHSGTSKRRRVTDERELHIPLEYGWQRETRIRNFGGRLQGEVAYYAPCGKKLRQYPEVIKYLSRNGIMDISRDNFSFSAKIRVGDFYEARDGPQGMQWCLLKEEDVIPRIRAMEGRRGRPPNPDRQRAREESRIRRRKGRPPNVGSTEFLDNTDAKLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIIAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQELERHRLDMERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKLEQRRLELEMAKELKKPNEDMCLADQKPLPELPRIPGLVLSGSTFSDCLMVVQFLRNFGKVLGFDVNIDVPNLSVLQEGLLNIGDSMGEVQDLLVRLLSAAVCDPGLITGYKAKTALGEHLLNVGVNRDNVSEILQIFMEAHCGQTELTESLKTKAFQAHTPAQKASVLAFLINELACSKSVVSEIDKNIDYMSNLRRDKWVVEGKLRKLRIIHAKKTGKRDTSGGIDLGEEQHPLGTPTPGRKRRRKGGDSDYDDDDDDDSDDQADEDDEDEEDKEDKKGKKTEICEDEDEGDQAASVEELEKQIEKLSKQQSQYRRKLFDASHSLRSMMFGQDRYRRRYWILPQCGGIFVEGMESGEGLEEIAKEREKLKKAKSIQIKEEIFETSEHTLNCSNPDHCEQKEDTKEKDNPNLFLQKPGSFSKLSKLLEVAKMPAESDVMTPKPNSSANGCTLSYQNSGKQSLGSIQSTATQSNTEKTDSNNLFSTSSSGPGKFYSPLPNDQLLKTLTEKNRQWFSLLPRTPCDDTSLTHASMSTASSVTPQSQPLSKSPSPAPAPLLGSSAQNPVGLNPFALSPLQVKSGVSVMGLQFCGWPAGVLTSNIPFTSPLPNLGSGLGLSEGNSNTFVTPNVAPSKSESPVPQNEKVSSTQPAAVEVAKPVDFPSPKPIPEEMQFGWWRIIDPEDLKALLKVLHLRGIREKALQKQIQKHLDYITQACIKNKDVAIIELNENEENQVTRDIVENWSIEEQAMEMDLNILQQVEDLERRVASASLQVKGWMCPEPASEREDLVYFEHKSFSKLCKEHDGEFTGEEEGSAHALERKSDNPLDIAVTRLADLERNIERRYLKSPLSTTIQIKLDNVGTVTVPAPAPSVSGDGDGIEEDIAPGLRVWRRALSEARSAAQVALCIQQLQKSIAWEKSIMKVYCQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACIAKASGQTLKIKKLHVKGKKSESKKGKKVTLTGDTEDEDSASTSSSLKRGVKDLKKRKMEENSSINISKQESFTSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHSMRKYFEKKWTDTFKVS", "length": 2211, "header": "tr|F1MG25-1|F1MG25_BOVIN Isoform 1 of Bromodomain adjacent to zinc finger domain protein 2B OS=Bos taurus OX=9913 GN=BAZ2B PE=3 SV=4 CANONICAL=F1MG25-1" }, "locus": { "chromosome": "2", "start_pos": 37045756, "end_pos": 36893457, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027534.7", "url": "https://www.ensembl.org/id/ENSBTAT00000027534.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027534.7", "url": "https://www.ensembl.org/id/ENSBTAP00000027534.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1293, "start_aa": "Thr", "end_pos": 1293, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1293", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1MG25", "url": "https://www.uniprot.org/uniprotkb/F1MG25" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1MG25", "url": "https://www.uniprot.org/uniprotkb/F1MG25" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", 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"database": "Ensembl Peptide", "id": "ENSBTAP00000056782.1", "url": "https://www.ensembl.org/id/ENSBTAP00000056782.1" } ] } }, { "isoform_ac": "F1MED5-1", "url": "https://www.uniprot.org/uniprotkb/F1MED5/entry", "sequence": { "sequence": "MRSGLTEARKEGREVQLRFLREAAAATTATRPALAPCTRCNAQTVLLGGAGGGGGGGRRREFSAMNLRGLFQDFNPSKFLIYACLLLFSVLLALRLDGIIQWSYWAVFAPIWLWKLMVIVGASVGTGVWARNPQYRAEGETCVEFKAMLIAVGIHLLLLMFEVLVCDRIERGSHFWLLVFMPLFFVSPVSVAACVWGFRHDRSLELEILCSVNILQFIFIALRLDKIIHWPWLVVCVPLWILMSFLCLVVLYYIVWSVLFLRSMDVIAEQRRTHITMALSWMTIVVPLLTFEILLVHKLDGHNAFSCIPIFVPLWLSLITLMATTFGQKGGNHWWFGIRKDFCQFLLEICPFLREYGNISYDLHHEGSEETEETPVPEPPKIAPMFRKKTRVVITQSPGKYVLPPPKLNIEMPD", "length": 414, "header": "tr|F1MED5-1|F1MED5_BOVIN Isoform 1 of Transmembrane protein 185A OS=Bos taurus OX=9913 GN=TMEM185A PE=4 SV=2 CANONICAL=F1MED5-1" }, "locus": { "chromosome": "X", "start_pos": 32141748, "end_pos": 32101229, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008956.5", "url": "https://www.ensembl.org/id/ENSBTAT00000008956.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008956.4", "url": "https://www.ensembl.org/id/ENSBTAP00000008956.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287ANX0-1", "protein_name": "Transmembrane protein 185A", "gene_name": "TMEM185A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNLRGLFQDFNPSKFLIYACLLLFSVLLALRLDGIIQWSYWAVFAPIWLWKLMVIVGASVGTGVWARNPQYRAEGETCVEFKAMLIAVGIHLLLLMFEVLVCDRIERGSHFWLLVFMPLFFVSPVSVAACVWGFRHDRSLELEILCSVNILQFIFIALRLDKIIHWPWLVVCVPLWILMSFLCLVVLYYIVWSVLFLRSMDVLAEQRRTHITMALSWMTIVVPLLTFEILLVHKLDGHNAFSCIPIFVPLWLSLITLMATTFGQKGGNHWWFGIRKDFCQFLLEVFPFLREYGNISYDLHHEENEETEETPVPEPPKIAPMFRKKARVVITQSPGKYVLPPPKLNIEMPD", "length": 350 }, "evidence": [ { "id": "F1MED5", "url": "https://omabrowser.org/oma/group/F1MED5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A2AF53-1", "protein_name": "Transmembrane protein 185A", "gene_name": "Tmem185a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNLRGLFQDFNPSKFLIYACLLLFSVLLALRLDGIIQWSYWAVFAPIWLWKLMVIVGASVGTGVWARNPQYRAEGETCVEFKAMLIAVGIHLLLLMFEVLVCDRIERGSHFWLLVFMPLFFVSPVSVAACVWGFRHDRSLELEILCSVNILQFIFIALRLDKIIHWPWLVVCVPLWILMSFLCLVVLYYIVWSVLFLRSMDVIAEQRRTHITMALSWMTIVVPLLTFEILLVHKLDGHNAFSCIPIFVPLWLSLITLMATTFGQKGGNHWWFGIRKDFCQFLLEIFPFLREYGNISYDLHHEDSEETEETPVPEPPKIAPMFRKKARVVITQSPGKYVLPPPKLNIEMPD", "length": 350 }, "evidence": [ { "id": "F1MED5", "url": "https://omabrowser.org/oma/group/F1MED5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZWX2-1", "protein_name": "Transmembrane protein 185A", "gene_name": "Tmem185a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNLRGLFQDFNPSKFLIYACLLLFSVLLALRLDGIIQWSYWAVFAPIWLWKLMVIVGASVGTGVWARNPQYRAEGETCVEFKAMLIAVGIHLLLLMFEVLVCDRIERGSHFWLLVFMPLFFVSPVSVAACVWGFRHDRSLELEILCSVNILQFIFIALRLDKIIHWPWLVVCVPLWILMSFLCLVVLYYIVWSVLFLRSMDVIAEQRRTHITMALSWMTIVVPLLTFEILLVHKLDGHNAFSCIPIFVPLWLSLITLMATTFGQKGGNHWWFGIRKDFCQFLLEIFPFLREYGNISYDLHHEDSEETEETPVPEPPKIAPMFRKKARVVITQSPGKYVLPPPKLNIEMPD", "length": 350 }, "evidence": [ { "id": "F1MED5", "url": "https://omabrowser.org/oma/group/F1MED5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7SYC7-1", "protein_name": "Transmembrane protein 185-like", "gene_name": "", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNLRGVFQDFNPSKFLIYACLLLFSVLLSLRLDGIIQWSYWAVFAPIWLWKLMVIIGASVGTGVWAHNPQYRAEGETCVEFKAMLIAVGIHLLLLTFEVLVCERVERASIPYWLLVFMPLFFVSPVSVAACVWGFRHDRSLELEILCSVNILQFIFIALKLDGIISWPWLVVCVPLWILMSFLCLVVLYYIVWSVLFLRSMDVIAEQRRTHITMAISWMTIVVPLLTFEILLVHKLDNHYSPNYVPVFVPLWVSLVTLMVTTFGQKGGNHWWFGIRKDFCQFLLELFPFLREYGNISYDLHHEDSDMSEELPIHEVPKIPTMFRKKTGVVITQSPGKYFVPPPKLCIDMPD", "length": 351 }, "evidence": [ { "id": "F1MED5", "url": "https://omabrowser.org/oma/group/F1MED5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8NFB2-1", "protein_name": "Transmembrane protein 185A", "gene_name": "TMEM185A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNLRGLFQDFNPSKFLIYACLLLFSVLLALRLDGIIQWSYWAVFAPIWLWKLMVIVGASVGTGVWARNPQYRAEGETCVEFKAMLIAVGIHLLLLMFEVLVCDRIERGSHFWLLVFMPLFFVSPVSVAACVWGFRHDRSLELEILCSVNILQFIFIALRLDKIIHWPWLVVCVPLWILMSFLCLVVLYYIVWSVLFLRSMDVIAEQRRTHITMALSWMTIVVPLLTFEILLVHKLDGHNAFSCIPIFVPLWLSLITLMATTFGQKGGNHWWFGIRKDFCQFLLEIFPFLREYGNISYDLHHEDNEETEETPVPEPPKIAPMFRKKARVVITQSPGKYVLPPPKLNIEMPD", "length": 350 }, "evidence": [ { "id": "F1MED5", "url": "https://omabrowser.org/oma/group/F1MED5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VWK7-1", "protein_name": "Transmembrane protein 185B", "gene_name": "Dmel\\CG14194", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNLESLFRDFNPCKFIVHCSLFIFVTLFALRLDNYIDWPYWAIFTPLWIWKCTAILGAIVGAIVWCRYPHYRLEGDAYTQFKAMLISLALHLILLMFELLACDKLTSDRHLWVLVFIPLIFGSVVSVGACVWAVKHDRSFELELFLAVNALQFVSLPLKLDRFVYWNWDVVFVPMWIVICLSLVSVLYNIIFCGIMMRTPEVSLQQKKAALNAAVGNICTVLPLLCFQVVICDKLDGELKFPYIVVFSPLLVSILALIVLSSSAKGGNMWWFGIRKSFSQFLLSAMPFLQEYGNISYHPETHSNAAQSMPLDAASSSTSMAASEQLHEFHKHDKKSKKGAKNDILKPVVPFVSIDLPD", "length": 358 }, "evidence": [ { "id": "F1MED5", "url": "https://omabrowser.org/oma/group/F1MED5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "F1MED5", "url": "https://www.uniprot.org/uniprotkb/F1MED5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 358, "end_pos": 360, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1MED5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 414, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1MED5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1MED5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 358, "end_pos": 360 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BM95-1", "uniprot_ac": "E1BM95", "uniprot_id": "E1BM95_BOVIN", "mass": { "chemical_mass": 86324.0, "monoisotopic_mass": 86324.0 }, "refseq": {}, "gene_names": [ { "name": "SCLT1", "type": "recommended", "evidence": [ { "id": "E1BM95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM95" } ] } ], "protein_names": [ { "name": "Sodium channel and clathrin linker 1", "type": "synonym", "evidence": [ { "id": "E1BM95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM95/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BM95", "url": "https://www.uniprot.org/uniprotkb/E1BM95" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SCLT1", "url": "https://www.uniprot.org/uniprotkb/E1BM95", "locus": { "chromosome": "17", "start_pos": 28933511, "end_pos": 28706473, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013611", "url": "https://www.ensembl.org/id/ENSBTAG00000013611" } ] } } ], "crossref": [ { "id": "E1BM95", "url": "https://alphafold.ebi.ac.uk/entry/E1BM95", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000013611", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013611", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "534830", "url": "https://www.ncbi.nlm.nih.gov/gene/534830", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:534830", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534830", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR35970", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35970", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35970:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35970:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF28159", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28159", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LMI2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LMI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RV34", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RV34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RV34-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RV34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T1Z7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1Z7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T1Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1Z7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T232", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T232", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T232-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T232-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TU57", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TU57-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU57-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM95", "url": "https://www.uniprot.org/uniprotkb/E1BM95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM95-1", "url": "https://www.uniprot.org/uniprotkb/E1BM95-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATEIDFLRDQNQRLNETLRRYQMENFFKYSTVQKGVFKGDGDDTLENSAADQSFLVPLITEYDKHLEELNGQLKYYQKQMGEMKLQFENVTKENERLHNELKDAVVAKQLQALPFGTEMGNEIYTDDETVRNLQEQLKLASQEKAQAVELWQTVSQELYKLQKLYQEHMTEAQIHVLESQKQKDQLTSFQQLTKHLHVTNENVELTNQHFLTTVTEQSAEIEQLRKQLRQAKLDLRVAAAKVEELTKVTEDLQGQMQKKEEDMVSAQGREEASDRRLQQLQSSIKQLEARLSVAVQEATQIRAERTHLEEQTRALQAKCSELEDEKYEAIVRARNSMQLLEEANLQKNQIIFPSVIRIQFSSVTQLYQILCNPMDCIMPGFPVHHQLLELAQTHVHQALLEEKQKQEAIEEMKKTVSQIVKDASLRTRTAIINTRKQYNIQISQLTEELSALQMECAEKQDQIERAIREKKAVEEELEKIYREGRINENDYRKLEEMHQRCLVAERSKDDLQLRLKTAENKIKQLEINSSEEISRCQEMIQKLQNILESERENCGFVSEQRLKLQQENEQLQKQTEDLRKIALEVQKKAKLKISTMEHEFSIKEHAFEVQLREMEDSNRNSTVELRHLLATTQKAANRWKEETKKLTESAEIRINNLKSELSRQKLHTQELLSQLEMANEKVVENEKLILEHQEKSNRLQRRLSEAEQRAASASQQLSVMTVQRRRAASMMNLENV", "length": 737, "header": "tr|E1BM95-1|E1BM95_BOVIN Isoform 1 of Sodium channel and clathrin linker 1 OS=Bos taurus OX=9913 GN=SCLT1 PE=4 SV=4 CANONICAL=E1BM95-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LMI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMI2/entry", "sequence": { "sequence": "MATEIDFLRDQNQRLNETLRRYQMENFFKYSTVQKGVFKGDGDDTLENSAADQSFLVPLITEYDKHLEELNGQLKYYQKQMGEMKLQFENVTKENERLHNELKDAVVAKQLQALPFGTEMGNEIYTDDETVRNLQEQLKLASQEKAQAVELWQTVSQELYKLQKLYQEHMTEAQIHVLESQKQKDQLTSFQQLTKHLHVTNENVELTNQHFLTTVTEQSAEIEQLRKQLRSELSRQKLHTQELLSQLEMANEKVVENEKLILEHQEKSNRLQRRLSEAEQRAASASQQLSVMTVQRRRAASMMNLENV", "length": 308, "header": "tr|A0A3Q1LMI2-1|E1BM95_BOVIN Computationally mapped isoform of Sodium channel and clathrin linker 1 OS=Bos taurus OX=9913 GN=SCLT1 PE=4 SV=2 CANONICAL=E1BM95-1" }, "locus": { "chromosome": "17", "start_pos": 28932795, "end_pos": 28706672, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079572.3", "url": "https://www.ensembl.org/id/ENSBTAT00000079572.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058076.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058076.2" } ] } }, { "isoform_ac": "A0AAA9RV34-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RV34/entry", "sequence": { "sequence": "MATEIDFLRDQNQRLNETLRRYQMENFFKYSTVQKGVFKGDGDDTLENSAADQSFLVPLITEYDKHLEELNGQLKYYQAQ", "length": 80, "header": "tr|A0AAA9RV34-1|A0AAA9RV34_BOVIN Computationally mapped isoform of Sodium channel and clathrin linker 1 OS=Bos taurus OX=9913 GN=SCLT1 PE=4 SV=1 CANONICAL=E1BM95-1" }, "locus": { "chromosome": "17", "start_pos": 28745283, "end_pos": 28706672, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000099664.2", "url": "https://www.ensembl.org/id/ENSBTAT00000099664.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076087.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076087.1" } ] } }, { "isoform_ac": "A0AAA9T1Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1Z7/entry", "sequence": { "sequence": "MATEIDFLRDQNQRLNETLRRYQMENFFKYSTVQVCTFSYAFWPSRCSLIHEFKQALGFGDGQKGVFKGDGDDTLENSAADQSFLVPLITEYDKHLEELNGQLKYYQKQMGEMKLQFENVTKENERLHNELKDAVVAKQLQALPFGTEMGNEIYTDDETVRNLQEQLKLASQEKAQAVELWQTVSQELYKLQKLYQEHMTEAQIHVLESQKQKDQLTSFQQLTKHLHVTNENVELTNQHFLTTVTEQSAEIEQLRKQLRQAKLDLRVAAAKVEELTKVTEDLQGQMQKKEEDMVSAQGREEASDRRLQQLQSSIKQLEARLSVAVQEATQIRAERTHLEEQTRALQAKCSELEDEKYEAIVRARNSMQLLEEANLQKNQALLEEKQKQEAIEEMKKTVSQIVKDASLRTRTAIINTRKQYNIQISQLTEELSALQMECAEKQDQIERAIREKKAVEEELEKIYREGRINENDYRKLEEMHQRCLVAERSKDDLQLRLKTAENKIKQLEINSSEEISRCQEMIQKLQNILESERENCGFVSEQRLKLQQENEQLQKQTEDLRKIALEVQKKAKLKISTMEHEFSIKEHAFEVQLREMEDSNRNSTVELRHLLATTQKAANRWKEETKKLTESAEIRINNLKSELSRQKLHTQELLSQLEMANEKVVENEKLILEHQEKSNRLQRRLSEAEQRAASASQQLSVMTVQRRRAASMMNLENV", "length": 718, "header": "tr|A0AAA9T1Z7-1|A0AAA9T1Z7_BOVIN Computationally mapped isoform of Sodium channel and clathrin linker 1 OS=Bos taurus OX=9913 GN=SCLT1 PE=4 SV=1 CANONICAL=E1BM95-1" }, "locus": { "chromosome": "17", "start_pos": 28932795, "end_pos": 28706672, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097033.2", "url": "https://www.ensembl.org/id/ENSBTAT00000097033.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090645.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090645.1" } ] } }, { "isoform_ac": "A0AAA9T232-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T232/entry", "sequence": { "sequence": "MATEIDFLRDQNQRLNETLRRYQMENFFKYSTVQKGVFKGDGDDTLENSAADQSFLVPLITEYDKHLEELNGQLKYYQKQMGEMKLQFENVTKENERLHNELKDAVVAKQLQALPFGTEMGNEIYTDDETVRNLQEQLKLASQEKAQAVELWQTVSQELYKLQKLYQEHMTEAQIHVLESQKQKDQLTSFQQLTKHLHVTNENVELTNQHFLTTVTEQSAEIEQLRKQLRQAKLDLRVAAAKVEELTKVTEDLQGQMQKKEEDMVSAQGREEASDRRLQQLQSSIKQLEARLSVAVQEATQIRAERTHLEEQTRALQAKCSELEDEKYEAIVRARNSMQLLEEANLQKNQIINTRKQYNIQISQLTEELSALQMECAEKQDQIERAIREKKAVEEELEKIYREGRINENDYRKLEEMHQRCLVAERSKDDLQLRLKTAENKIKQLEINSSEEISRCQEMIQKLQNILESERENCGFVSEQRLKLQQENEQLQKQTEDLRKIALEVQKKAKLKISTMEHEFSIKEHAFEVQLREMEDSNRNSTVELRHLLATTQKAANRWKEETKKLTESAEIRINNLKSELSRQKLHTQELLSQLEMANEKVVENEKLILEHQEKSNRLQRRLSEAEQRAASASQQLSVMTVQRRRAASMMNLENV", "length": 656, "header": "tr|A0AAA9T232-1|A0AAA9T232_BOVIN Computationally mapped isoform of Sodium channel and clathrin linker 1 OS=Bos taurus OX=9913 GN=SCLT1 PE=4 SV=1 CANONICAL=E1BM95-1" }, "locus": { "chromosome": "17", "start_pos": 28932795, "end_pos": 28706672, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130095.2", "url": "https://www.ensembl.org/id/ENSBTAT00000130095.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090687.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090687.1" } ] } }, { "isoform_ac": "A0AAA9TU57-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU57/entry", "sequence": { "sequence": "MATEIDFLRDQNQRLNETLRRYQMENFFKYSTVQKGVFKGDGDDTLENSAADQSFLVPLITEYDKHLEELNGQLKYYQKQMGEMKLQFENVTKENERSELSRQKLHTQELLSQLEMANEKVVENEKLILEHQEKSNRLQRRLSEAEQRAASASQQLSVMTVQRRRAASMMNLENV", "length": 175, "header": "tr|A0AAA9TU57-1|A0AAA9TU57_BOVIN Computationally mapped isoform of Sodium channel and clathrin linker 1 OS=Bos taurus OX=9913 GN=SCLT1 PE=4 SV=1 CANONICAL=E1BM95-1" }, "locus": { "chromosome": "17", "start_pos": 28932795, "end_pos": 28706672, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089509.2", "url": "https://www.ensembl.org/id/ENSBTAT00000089509.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100631.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100631.1" } ] } }, { "isoform_ac": "E1BM95-1", "url": "https://www.uniprot.org/uniprotkb/E1BM95/entry", "sequence": { "sequence": "MATEIDFLRDQNQRLNETLRRYQMENFFKYSTVQKGVFKGDGDDTLENSAADQSFLVPLITEYDKHLEELNGQLKYYQKQMGEMKLQFENVTKENERLHNELKDAVVAKQLQALPFGTEMGNEIYTDDETVRNLQEQLKLASQEKAQAVELWQTVSQELYKLQKLYQEHMTEAQIHVLESQKQKDQLTSFQQLTKHLHVTNENVELTNQHFLTTVTEQSAEIEQLRKQLRQAKLDLRVAAAKVEELTKVTEDLQGQMQKKEEDMVSAQGREEASDRRLQQLQSSIKQLEARLSVAVQEATQIRAERTHLEEQTRALQAKCSELEDEKYEAIVRARNSMQLLEEANLQKNQIIFPSVIRIQFSSVTQLYQILCNPMDCIMPGFPVHHQLLELAQTHVHQALLEEKQKQEAIEEMKKTVSQIVKDASLRTRTAIINTRKQYNIQISQLTEELSALQMECAEKQDQIERAIREKKAVEEELEKIYREGRINENDYRKLEEMHQRCLVAERSKDDLQLRLKTAENKIKQLEINSSEEISRCQEMIQKLQNILESERENCGFVSEQRLKLQQENEQLQKQTEDLRKIALEVQKKAKLKISTMEHEFSIKEHAFEVQLREMEDSNRNSTVELRHLLATTQKAANRWKEETKKLTESAEIRINNLKSELSRQKLHTQELLSQLEMANEKVVENEKLILEHQEKSNRLQRRLSEAEQRAASASQQLSVMTVQRRRAASMMNLENV", "length": 737, "header": "tr|E1BM95-1|E1BM95_BOVIN Isoform 1 of Sodium channel and clathrin linker 1 OS=Bos taurus OX=9913 GN=SCLT1 PE=4 SV=4 CANONICAL=E1BM95-1" }, "locus": { "chromosome": "17", "start_pos": 28932795, "end_pos": 28706672, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061229.5", "url": "https://www.ensembl.org/id/ENSBTAT00000061229.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053288.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053288.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:534830", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534830", "resource": "KEGG Pathway" }, { "id": "R-BTA-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "clustering of voltage-gated sodium channels", "id": "GO:0045162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045162", "evidence": [ { "database": "UniProtKB", "id": "E1BM95", "url": "https://www.uniprot.org/uniprotkb/E1BM95" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "E1BM95", "url": "https://www.uniprot.org/uniprotkb/E1BM95" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "E1BM95", "url": "https://www.uniprot.org/uniprotkb/E1BM95" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "E1BM95", "url": "https://www.uniprot.org/uniprotkb/E1BM95" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "E1BM95", "url": "https://www.uniprot.org/uniprotkb/E1BM95" } ], "pmid": "" }, { "name": "ciliary transition fiber", "id": "GO:0097539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097539", "evidence": [ { "database": "UniProtKB", "id": "E1BM95", "url": "https://www.uniprot.org/uniprotkb/E1BM95" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" }, { "start_pos": 529, "end_pos": 531, "annotation": "n_glycosylation_sequon" }, { "start_pos": 621, "end_pos": 623, "annotation": "n_glycosylation_sequon" }, { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BM95-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 737, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BM95-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BM95" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 16, "end_pos": 18 }, { "start_pos": 529, "end_pos": 531 }, { "start_pos": 621, "end_pos": 623 }, { "start_pos": 90, "end_pos": 92 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1MAV7-1", "uniprot_ac": "F1MAV7", "uniprot_id": "F1MAV7_BOVIN", "mass": { "chemical_mass": 31592.0, "monoisotopic_mass": 31592.0 }, "refseq": {}, "gene_names": [ { "name": "TMEM45A", "type": "recommended", "evidence": [ { "id": "F1MAV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAV7" } ] } ], "protein_names": [ { "name": "Transmembrane protein 45A", "type": "synonym", "evidence": [ { "id": "F1MAV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAV7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1MAV7", "url": "https://www.uniprot.org/uniprotkb/F1MAV7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TMEM45A", "url": "https://www.uniprot.org/uniprotkb/F1MAV7", "locus": { "chromosome": "1", "start_pos": 45061337, "end_pos": 44948291, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004459", "url": "https://www.ensembl.org/id/ENSBTAG00000004459" } ] } } ], "crossref": [ { "id": "F1MAV7", "url": "https://alphafold.ebi.ac.uk/entry/F1MAV7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004459", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004459", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "509461", "url": "https://www.ncbi.nlm.nih.gov/gene/509461", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042127", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042127", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LMS3", "url": "https://www.orthodb.org/?gene=A0A3Q1LMS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MAV7", "url": "https://www.orthodb.org/?gene=F1MAV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16007", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16007", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16007:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16007:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04819", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04819", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LMS3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LMS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMS3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S5M9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5M9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S5M9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5M9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SMT4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SMT4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T2I8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2I8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T2I8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2I8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MAV7", "url": "https://www.uniprot.org/uniprotkb/F1MAV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MAV7-1", "url": "https://www.uniprot.org/uniprotkb/F1MAV7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNFKGHALPGSFFFILGIWWTIKYILKYAFKKQKRTSYLDSKALFHRAEMLEGIVIVGMTLTGILGEQFYPGGPHLTLYDYKEGQWVQLLSWQHFTMYFFFGLLGVTNILSSTVVSLPASFSKLMLSNALFVEAFVFYNHIHGREMLDIFVHKLLVLVVFSTGVIAFMELFAQTSITVELLRTSLFLLQGSWFWQIGFILYPPSGGPAWDLMDHDNVMFLSICFCWHYATAISIVGAIYVFVTWLVKSRFTRFCPSEVGLLKNAEREPESEEEM", "length": 275, "header": "tr|F1MAV7-1|F1MAV7_BOVIN Isoform 1 of Transmembrane protein 45A OS=Bos taurus OX=9913 GN=TMEM45A PE=3 SV=1 CANONICAL=F1MAV7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LMS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMS3/entry", "sequence": { "sequence": "MGNFKGHALPGSFFFILGIWWTIKYILKYAFKKQKRTSYLDSKALFHRAEMLEGIVIVGMTLTGILGEQFYPGGPHLTLYDYKEGQWVQLLSWQHFTMYFFFGLLGVTNILSSTVVSLPASFSKLMLSNALFVEAFVFYNHIHGREMLDIFVHKLLVLVVFSTGVIAFMELFAQTSITVELLRTSLFLLQGSWFWQIGFILYPPSGGPAWDLMDHDNVMFLSICFCWHYATAISIVGAIYVFVTWLTSGPHLLRGCAASKNKASIQAISLPHVSSHPEPKEDYCLFLFQKPSDH", "length": 294, "header": "tr|A0A3Q1LMS3-1|F1MAV7_BOVIN Computationally mapped isoform of Transmembrane protein 45A OS=Bos taurus OX=9913 GN=TMEM45A PE=3 SV=1 CANONICAL=F1MAV7-1" }, "locus": { "chromosome": "1", "start_pos": 45057113, "end_pos": 45033538, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074340.3", "url": "https://www.ensembl.org/id/ENSBTAT00000074340.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061201.1", "url": "https://www.ensembl.org/id/ENSBTAP00000061201.1" } ] } }, { "isoform_ac": "A0AAA9S5M9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5M9/entry", "sequence": { "sequence": "MTPLRLWSREETEETVMGNFKGHALPGSFFFILGIWWTIKYILKYAFKKQKRTSYLDSKALFHRAEMLEGIVIVGMTLTGILGEQFYPGGPHLTLYDYKEGQWVQLLSWQHFTMYFFFGLLGVTNILSSTVVSLPASFSKLMLSNALFVEAFVFYNHIHGREMLDIFVHKLLVLVVFSTGVIAFMELFAQTSITVELLRTSLFLLQGSWFWQIGFILYPPSGGPAWDLMDHDNVMFLSICFCWHYATAISIVGAIYVFVTWLVKSRFTRFCPSEVGLLKNAEREPESEEEM", "length": 291, "header": "tr|A0AAA9S5M9-1|A0AAA9S5M9_BOVIN Computationally mapped isoform of Transmembrane protein 45A OS=Bos taurus OX=9913 GN=TMEM45A PE=3 SV=2 CANONICAL=F1MAV7-1" }, "locus": { "chromosome": "1", "start_pos": 45061011, "end_pos": 44979491, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000100253.2", "url": "https://www.ensembl.org/id/ENSBTAT00000100253.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077477.2", "url": "https://www.ensembl.org/id/ENSBTAP00000077477.2" } ] } }, { "isoform_ac": "A0AAA9SMT4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT4/entry", "sequence": { "sequence": "MRWLDVITDMNLVMGNFKGHALPGSFFFILGIWWTIKYILKYAFKKQKRTSYLDSKALFHRAEMLEGIVIVGMTLTGILGEQFYPGGPHLTLYDYKEGQWVQLLSWQHFTMYFFFGLLGVTNILSSTVVSLPASFSKLMLSNALFVEAFVFYNHIHGREMLDIFVHKLLVLVVFSTGVIAFMELFAQTSITVELLRTSLFLLQGSWFWQIGFILYPPSGGPAWDLMDHDNVMFLSICFCWHYATAISIVGAIYVFVTWLVKSRFTRFCPSEVGLLKNAEREPESEEEM", "length": 288, "header": "tr|A0AAA9SMT4-1|A0AAA9SMT4_BOVIN Computationally mapped isoform of Transmembrane protein 45A OS=Bos taurus OX=9913 GN=TMEM45A PE=3 SV=1 CANONICAL=F1MAV7-1" }, "locus": { "chromosome": "1", "start_pos": 45061011, "end_pos": 45027654, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103610.2", "url": "https://www.ensembl.org/id/ENSBTAT00000103610.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085284.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085284.1" } ] } }, { "isoform_ac": "A0AAA9T2I8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2I8/entry", "sequence": { "sequence": "MVFMGNFKGHALPGSFFFILGIWWTIKYILKYAFKKQKRTSYLDSKALFHRAEMLEGIVIVGMTLTGILGEQFYPGGPHLTLYDYKEGQWVQLLSWQHFTMYFFFGLLGVTNILSSTVVSLPASFSKLMLSNALFVEAFVFYNHIHGREMLDIFVHKLLVLVVFSTGVIAFMELFAQTSITVELLRTSLFLLQGSWFWQIGFILYPPSGGPAWDLMDHDNVMFLSICFCWHYATAISIVGAIYVFVTWLVKSRFTRFCPSEVGLLKNAEREPESEEEM", "length": 278, "header": "tr|A0AAA9T2I8-1|A0AAA9T2I8_BOVIN Computationally mapped isoform of Transmembrane protein 45A OS=Bos taurus OX=9913 GN=TMEM45A PE=3 SV=2 CANONICAL=F1MAV7-1" }, "locus": { "chromosome": "1", "start_pos": 45061011, "end_pos": 44967334, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116729.2", "url": "https://www.ensembl.org/id/ENSBTAT00000116729.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089874.2", "url": "https://www.ensembl.org/id/ENSBTAP00000089874.2" } ] } }, { "isoform_ac": "F1MAV7-1", "url": "https://www.uniprot.org/uniprotkb/F1MAV7/entry", "sequence": { "sequence": "MGNFKGHALPGSFFFILGIWWTIKYILKYAFKKQKRTSYLDSKALFHRAEMLEGIVIVGMTLTGILGEQFYPGGPHLTLYDYKEGQWVQLLSWQHFTMYFFFGLLGVTNILSSTVVSLPASFSKLMLSNALFVEAFVFYNHIHGREMLDIFVHKLLVLVVFSTGVIAFMELFAQTSITVELLRTSLFLLQGSWFWQIGFILYPPSGGPAWDLMDHDNVMFLSICFCWHYATAISIVGAIYVFVTWLVKSRFTRFCPSEVGLLKNAEREPESEEEM", "length": 275, "header": "tr|F1MAV7-1|F1MAV7_BOVIN Isoform 1 of Transmembrane protein 45A OS=Bos taurus OX=9913 GN=TMEM45A PE=3 SV=1 CANONICAL=F1MAV7-1" }, "locus": { "chromosome": "1", "start_pos": 45061011, "end_pos": 45033538, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005845.6", "url": "https://www.ensembl.org/id/ENSBTAT00000005845.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005845.3", "url": "https://www.ensembl.org/id/ENSBTAP00000005845.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1MAV7", "url": "https://www.uniprot.org/uniprotkb/F1MAV7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1MAV7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 275, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1MAV7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1MAV7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1MBQ4-1", "uniprot_ac": "F1MBQ4", "uniprot_id": "F1MBQ4_BOVIN", "mass": { "chemical_mass": 69324.0, "monoisotopic_mass": 69324.0 }, "refseq": { "ac": "XP_010816107", "name": "protein DENND6A isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010816107" }, "gene_names": [ { "name": "DENND6A", "type": "recommended", "evidence": [ { "id": "F1MBQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBQ4" } ] }, { "name": "DENND6A", "type": "synonym", "evidence": [ { "id": "XP_010816107", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010816107" } ] } ], "protein_names": [ { "name": "DENN domain containing 6A", "type": "synonym", "evidence": [ { "id": "F1MBQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBQ4/entry#names_and_taxonomy" } ] }, { "name": "protein DENND6A isoform X2", "type": "synonym", "evidence": [ { "id": "XP_010816107", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010816107" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1MBQ4", "url": "https://www.uniprot.org/uniprotkb/F1MBQ4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DENND6A", "url": "https://www.uniprot.org/uniprotkb/F1MBQ4", "locus": { "chromosome": "22", "start_pos": 43603656, "end_pos": 43531077, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018433", "url": "https://www.ensembl.org/id/ENSBTAG00000018433" } ] } } ], "crossref": [ { "id": "F1MBQ4", "url": "https://alphafold.ebi.ac.uk/entry/F1MBQ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018433", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018433", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "537662", "url": "https://www.ncbi.nlm.nih.gov/gene/537662", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018307", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018307", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024224", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024224", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13677", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13677", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13677:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13677:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09794", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09794", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8876198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_010816107", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010816107", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LMV8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LMV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RWA7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RWA7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2P6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2P6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2P6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2P6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MBQ4", "url": "https://www.uniprot.org/uniprotkb/F1MBQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MBQ4-1", "url": "https://www.uniprot.org/uniprotkb/F1MBQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALRGLAGSGPGSRGPLDEAVAADKEREAPAVVVAGATPEDDEEDEGRSRGLLRWDGFSAWLHCVCVVGFDLELGQAVEVIYPQHSRLTDKEKTNICYLSFPDSNSGCLGDTQFCFRFRQSSGRRVSLHCLLDQFDKDLPVYLKKDPAYFYGYVYFRQVRDKTLKRGYFQKSLVLISKLPYIHFFHTVLKQIAPEYFEKNEPYLEAACNDVDRWPAPVPGKTLYLPIMGVVMKVRIPTCHDKPGTTQIVQLTQQGDAHISVILPTVHEVDLFRCFCPVFLHSQMLWELVLLGEPLVVMAPSPSESSETVLALVNCISPLKYFSDFRPYFTIHDSEFKEYTTRTQAPPSVILGVTNPFFAKTLQHWPHIIRIGDLKPAGEIPKQVKVKKLKNLKTLDSKPGVYTSYKPYLNRDEDIIKQLQKGVQQKRPSEAQSVILRRYFLELTQSFIIPLERYVASLMPLQKSISPWKSPPQLRQFLPEEFMKTLEKTGPQLTSRIKGDWIGLYRHFLKSPNFDGWFKTRRKEMTQKLEALHLEALCEEDLLLWTQKHTEVETVDLVLKLKNKLVFLIQPHPAECTSWNKQLQNHLLLLLLSRFSRVRLCVTP", "length": 604, "header": "tr|F1MBQ4-1|F1MBQ4_BOVIN Isoform 1 of DENN domain containing 6A OS=Bos taurus OX=9913 GN=DENND6A PE=3 SV=4 CANONICAL=F1MBQ4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LMV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV8/entry", "sequence": { "sequence": "MITCAAAPPRPGPSPAAATAPAAPARSPAPSAARSSVEAARTARGRRMALRGLAGSGPGSRGPLDEAVAADKEREAPAVVVAGATPEDDEEDEGRSRGLLRWDGFSAWLHCVCVVGFDLELGQAVEVIYPQHSRLTDKEKTNICYLSFPDSNSGCLGDTQFCFRFRQSSGRRVSLHCLLDQFDKDLPVYLKKDPAYFYGYVYFRQVRDKTLKRGYFQKSLVLISKLPYIHFFHTVLKQIAPEYFEKNEPYLEAACNDVDRWPAPVPGKTLYLPIMGVVMKVRIPTCHDKPGTTQIVQLTQQGDAHISVILPTVHEVDLFRCFCPVFLHSQMLWELVLLGEPLVVMAPSPSESSETVLALVNCISPLKYFSDFRPYFTIHDSEFKEYTTRTQAPPSVILGVTNPFFAKTLQHWPHIIRIGDLKPAGEIPKQVKVKKLKNLKTLDSKPGVYTSYKPYLNRDEDIIKQLQKGVQQKRPSEAQSVILRRYFLELTQSFIIPLERYVASLMPLQKSISPWKSPPQLRQFLPEEFMKTLEKTGPQLTSRIKGDWIGLYRHFLKSPNFDGWFKTRRKEMTQKLEALHLEALCEEDLLLWTQKHTEVETVDLVLKLKNKLGDISRGG", "length": 619, "header": "tr|A0A3Q1LMV8-1|F1MBQ4_BOVIN Computationally mapped isoform of DENN domain containing 6A OS=Bos taurus OX=9913 GN=DENND6A PE=3 SV=2 CANONICAL=F1MBQ4-1" }, "locus": { "chromosome": "22", "start_pos": 43593089, "end_pos": 43531245, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087251.2", "url": "https://www.ensembl.org/id/ENSBTAT00000087251.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061254.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061254.2" } ] } }, { "isoform_ac": "A0AAA9RWA7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWA7/entry", "sequence": { "sequence": "MALRGLAGSGPGSRGPLDEAVAADKEREAPAVVVAGATPEDDEEDEGRSRGLLRWDGFSAWLHCVCVVGFDLELGQAVEIRRIDRVVMKTAAAAAAAKSLQSCPTLCDPIDVSPPGSPIPGILQVIYPQHSRLTDKEKTNICYLSFPDSNSGCLGDTQFCFRFRQSSGRRVSLHCLLDQFDKDLPVYLKKDPAYFYGYVYFRQVRDKTLKRGYFQKSLVLISKLPYIHFFHTVLKQIAPEYFEKNEPYLEAACNDVDRWPAPVPGKTLYLPIMGVVMKVRIPTCHDKPGTTQIVQLTQQGDAHISVILPTVHEVDLFRCFCPVFLHSQMLWELVLLGEPLVVMAPSPSESSETVLALVNCISPLKYFSDFRPYFTIHDSEFKEYTTRTQAPPSVILGVTNPFFAKTLQHWPHIIRIGDLKPAGEIPKQVKVKKLKNLKTLDSKPGVYTSYKPYLNRDEDIIKQLQKGVQQKRPSEAQSVILRRYFLELTQSFIIPLERYVASLMPLQKSISPWKSPPQLRQFLPEEFMKTLEKTGPQLTSRIKGDWIGLYRHFLKSPNFDGWFKTRRKEMTQKLEALHLEALCEEDLLLWTQKHTEVETVDLVLKLKNKLLQADREHLPVKPDTMEKLRTHIDAIILALPEDLQGILLKTSMT", "length": 653, "header": "tr|A0AAA9RWA7-1|A0AAA9RWA7_BOVIN Computationally mapped isoform of DENN domain containing 6A OS=Bos taurus OX=9913 GN=DENND6A PE=3 SV=1 CANONICAL=F1MBQ4-1" }, "locus": { "chromosome": "22", "start_pos": 43577586, "end_pos": 43531386, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000108615.1", "url": "https://www.ensembl.org/id/ENSBTAT00000108615.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075398.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075398.1" } ] } }, { "isoform_ac": "A0ABI0P2P6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2P6/entry", "sequence": { "sequence": "MITCAAAPPRPGPSPAAATAPAAPARSPAPSAARSSVEAARTARGRRMALRGLAGSGPGSRGPLDEAVAADKEREAPAVVVAGATPEDDEEDEGRSRGLLRWDGFSAWLHCVCVVGFDLELGQAVEVIYPQHSRLTDKEKTNICYLSFPDSNSGCLGDTQFCFRFRQSSGRRVSLHCLLDQFDKDLPVYLKKDPAYFYGYVYFRQVRDKTLKRGYFQKSLVLISKLPYIHFFHTVLKQIAPEYFEKNEPYLEAACNDVDRWPAPVPGKTLYLPIMGVVMKVRIPTCHDKPGTTQIVQLTQQGDAHISVILPTVHEVDLFRCFCPVFLHSQMLWELVLLGEPLVVMAPSPSESSETVLALVNCISPLKYFSDFRPYFTIHDSEFKEYTTRTQAPPSVILGVTNPFFAKTLQHWPHIIRIGDLKPAGEIPKQVKVKKLKNLKTLDSKPGVYTSYKPYLNRDEDIIKQLQKGVQQKRPSEAQSVILRRYFLELTQSFIIPLERYVASLMPLQKSISPWKSPPQLRQFLPEEFMKTLEKTGPQLTSRIKGDWIGLYRHFLKSPNFDGWFKTRRKEMTQKLEALHLEALCEEDLLLWTQKHTEVETVDLVLKLKNKLLQADREHLPVKPDTMEKLRTHIDAIILALPEDLQGILLKTSMT", "length": 655, "header": "tr|A0ABI0P2P6-1|A0ABI0P2P6_BOVIN Computationally mapped isoform of DENN domain containing 6A OS=Bos taurus OX=9913 GN=DENND6A PE=3 SV=1 CANONICAL=F1MBQ4-1" }, "locus": { "chromosome": "22", "start_pos": 43577586, "end_pos": 43531245, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148615.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148615.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105350.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105350.1" } ] } }, { "isoform_ac": "F1MBQ4-1", "url": "https://www.uniprot.org/uniprotkb/F1MBQ4/entry", "sequence": { "sequence": "MALRGLAGSGPGSRGPLDEAVAADKEREAPAVVVAGATPEDDEEDEGRSRGLLRWDGFSAWLHCVCVVGFDLELGQAVEVIYPQHSRLTDKEKTNICYLSFPDSNSGCLGDTQFCFRFRQSSGRRVSLHCLLDQFDKDLPVYLKKDPAYFYGYVYFRQVRDKTLKRGYFQKSLVLISKLPYIHFFHTVLKQIAPEYFEKNEPYLEAACNDVDRWPAPVPGKTLYLPIMGVVMKVRIPTCHDKPGTTQIVQLTQQGDAHISVILPTVHEVDLFRCFCPVFLHSQMLWELVLLGEPLVVMAPSPSESSETVLALVNCISPLKYFSDFRPYFTIHDSEFKEYTTRTQAPPSVILGVTNPFFAKTLQHWPHIIRIGDLKPAGEIPKQVKVKKLKNLKTLDSKPGVYTSYKPYLNRDEDIIKQLQKGVQQKRPSEAQSVILRRYFLELTQSFIIPLERYVASLMPLQKSISPWKSPPQLRQFLPEEFMKTLEKTGPQLTSRIKGDWIGLYRHFLKSPNFDGWFKTRRKEMTQKLEALHLEALCEEDLLLWTQKHTEVETVDLVLKLKNKLVFLIQPHPAECTSWNKQLQNHLLLLLLSRFSRVRLCVTP", "length": 604, "header": "tr|F1MBQ4-1|F1MBQ4_BOVIN Isoform 1 of DENN domain containing 6A OS=Bos taurus OX=9913 GN=DENND6A PE=3 SV=4 CANONICAL=F1MBQ4-1" }, "locus": { "chromosome": "22", "start_pos": 43603524, "end_pos": 43531386, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024525.7", "url": "https://www.ensembl.org/id/ENSBTAT00000024525.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024525.6", "url": "https://www.ensembl.org/id/ENSBTAP00000024525.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "F1MBQ4", "url": "https://www.uniprot.org/uniprotkb/F1MBQ4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "F1MBQ4", "url": "https://www.uniprot.org/uniprotkb/F1MBQ4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of cell-cell adhesion mediated by cadherin", "id": "GO:2000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000049", "evidence": [ { "database": "UniProtKB", "id": "F1MBQ4", "url": "https://www.uniprot.org/uniprotkb/F1MBQ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1MBQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBQ4" }, { "id": "PS50211", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50211" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UDENN", "eco_id": "ECO_0000259", "start_pos": 63, "end_pos": 528, "start_aa": "His", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1MFI4-1", "uniprot_ac": "F1MFI4", "uniprot_id": "F1MFI4_BOVIN", "mass": { "chemical_mass": 70833.0, "monoisotopic_mass": 70833.0 }, "refseq": {}, "gene_names": [ { "name": "CRTAC1", "type": "recommended", "evidence": [ { "id": "F1MFI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFI4" } ] } ], "protein_names": [ { "name": "Cartilage acidic protein 1", "type": "synonym", "evidence": [ { "id": "F1MFI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFI4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1MFI4", "url": "https://www.uniprot.org/uniprotkb/F1MFI4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CRTAC1", "url": "https://www.uniprot.org/uniprotkb/F1MFI4", "locus": { "chromosome": "26", "start_pos": 19004535, "end_pos": 19170819, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008102", "url": "https://www.ensembl.org/id/ENSBTAG00000008102" } ] } } ], "crossref": [ { "id": "F1MFI4", "url": "https://alphafold.ebi.ac.uk/entry/F1MFI4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008102", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008102", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100139581", "url": "https://www.ncbi.nlm.nih.gov/gene/100139581", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011519", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011519", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013517", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013517", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027039", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027039", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LN98", "url": "https://www.orthodb.org/?gene=A0A3Q1LN98", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MFI4", "url": "https://www.orthodb.org/?gene=F1MFI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16026", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16026", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16026:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16026:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07593", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07593", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13517", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13517", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LN98", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LN98-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN98-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9THC0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9THC0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THC0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MFI4", "url": "https://www.uniprot.org/uniprotkb/F1MFI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MFI4-1", "url": "https://www.uniprot.org/uniprotkb/F1MFI4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASADPGMFQVFLFLLLLWFLPLTEGSQGAEPMFTAVTNSVLPPDYDSNPTQLNYGVAVTDVDRDGDFEIVVAGYNGPNLVLKYDRAQKRLVNIAMDERSSPYYALRDRQGNAIGVTACDIDGDGREEIYFLNTNNAFSGVATYTDKLFKFRNNRWEDILSDEVNVARGVASLFAGRSVACVDRKGSGRYSIYIANYAYGNVGPDALIEMDPEASDLSRGILALRDVAAEAGVSKYTGGRGVSVGPILSSSASDIFCDNENGPNFLFHNRGDGTFVDAAASAGVDDPHQHGRGVALADFNRDGKVDIVYGNWNGPHRLYLQMSAHGKVRFRDIASPKFSMPSPVRTVIAADFDNDQELEVFFNNFAHRSSSANRLFRVIHREHGDPLIEELNPGDALEPEGRGTGGVVTDFDGDGMLDLILSHGESMAQPLSVFRGNQGFSNNWLRVVPRTRFGAFARGAKVVLYTKKSGAHLRIIDGGSGYLCEMEPVAHFGLGKDEASSVEVTWPDGKMASRNVASSEMNSVLEIPYPRDDDRPQDPASLECGQGFSQQENGHCADTNECIQFPFVCPRDKPVCVNTYGSYRCRTNKRCSRGYEPNEDGTACVGTLGQSPAPRPTAPTTAAAAAAAATAARAAAAAPVLVDGDLDLGVKEGCK", "length": 656, "header": "tr|F1MFI4-1|F1MFI4_BOVIN Isoform 1 of Cartilage acidic protein 1 OS=Bos taurus OX=9913 GN=CRTAC1 PE=4 SV=4 CANONICAL=F1MFI4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LN98-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN98/entry", "sequence": { "sequence": "MAASADPGMFQVFLFLLLLWFLPLTEGSQGAEPMFTAVTNSVLPPDYDSNPTQLNYGVAVTDVDRDGDFEIVVAGYNGPNLVLKYDRAQKRLVNIAMDERSSPYYALRDRQGNAIGVTACDIDGDGREEIYFLNTNNAFSGVATYTDKLFKFRNNRWEDILSDEVNVARGVASLFAGRSVACVDRKGSGRYSIYIANYAYGNVGPDALIEMDPEASDLSRGILALRDVAAEAGVSKYTGGRGVSVGPILSSSASDIFCDNENGPNFLFHNRGDGTFVDAAASAGVDDPHQHGRGVALADFNRDGKVDIVYGNWNGPHRLYLQMSAHGKVRFRDIASPKFSMPSPVRTVIAADFDNDQELEVFFNNFAHRSSSANRLFRVIHREHGDPLIEELNPGDALEPEGRGTGGVVTDFDGDGMLDLILSHGESMAQPLSVFRGNQGFSNNWLRVVPRTRFGAFARGAKVVLYTKKSGAHLRIIDGGSGYLCEMEPVAHFGLGKDEASSVEVTWPDGKMASRNVASSEMNSVLEIPYPRDDDRPQDPASLECGQGFSQQENGHCADTNECIQFPFVCPRDKPVCVNTYGSYRCRTNKRCSRGYEPNEDGTACVASLTPSEESR", "length": 616, "header": "tr|A0A3Q1LN98-1|F1MFI4_BOVIN Computationally mapped isoform of Cartilage acidic protein 1 OS=Bos taurus OX=9913 GN=CRTAC1 PE=4 SV=1 CANONICAL=F1MFI4-1" }, "locus": { "chromosome": "26", "start_pos": 19170684, "end_pos": 19019456, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084335.1", "url": "https://www.ensembl.org/id/ENSBTAT00000084335.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058434.1", "url": "https://www.ensembl.org/id/ENSBTAP00000058434.1" } ] } }, { "isoform_ac": "A0AAA9THC0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THC0/entry", "sequence": { "sequence": "MAASADPGMFQVFLFLLLLWFLPLTEGSQGAEPMFTAVTNSVLPPDYDSNPTQLNYGVAVTDVDRDGDFEIVVAGYNGPNLVLKYDRAQKRLVNIAMDERSSPYYALRDRQGNAIGVTACDIDGDGREEIYFLNTNNAFSGVATYTDKLFKFRNNRWEDILSDEVNVARGVASLFAGRSVACVDRKGSGRYSIYIANYAYGNVGPDALIEMDPEASDLSRGILALRDVAAEAGVSKYTGGRGVSVGPILSSSASDIFCDNENGPNFLFHNRGDGTFVDAAASAGVDDPHQHGRGVALADFNRDGKVDIVYGNWNGPHRLYLQMSAHGKVRFRDIASPKFSMPSPVRTVIAADFDNDQELEVFFNNFAHRSSSANRLFRVIHREHGDPLIEELNPGDALEPEGRGTGGVVTDFDGDGMLDLILSHGESMAQPLSVFRGNQGFSNNWLRVVPRTRFGAFARGAKVVLYTKKSGAHLRIIDGGSGYLCEMEPVAHFGLGKDEASSVEVTWPDGKMASRNVASSEMNSVLEIPYPRDDDRPQDPASLECGQGFSQQENGHCADTNECIQFPFVCPRDKPVCVNTYGSYRCRTNKRCSRGYEPNEDGTACVAQVAFLASLTPSEESR", "length": 622, "header": "tr|A0AAA9THC0-1|A0AAA9THC0_BOVIN Computationally mapped isoform of Cartilage acidic protein 1 OS=Bos taurus OX=9913 GN=CRTAC1 PE=4 SV=1 CANONICAL=F1MFI4-1" }, "locus": { "chromosome": "26", "start_pos": 19170684, "end_pos": 19019456, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109047.1", "url": "https://www.ensembl.org/id/ENSBTAT00000109047.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097641.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097641.1" } ] } }, { "isoform_ac": "F1MFI4-1", "url": "https://www.uniprot.org/uniprotkb/F1MFI4/entry", "sequence": { "sequence": "MAASADPGMFQVFLFLLLLWFLPLTEGSQGAEPMFTAVTNSVLPPDYDSNPTQLNYGVAVTDVDRDGDFEIVVAGYNGPNLVLKYDRAQKRLVNIAMDERSSPYYALRDRQGNAIGVTACDIDGDGREEIYFLNTNNAFSGVATYTDKLFKFRNNRWEDILSDEVNVARGVASLFAGRSVACVDRKGSGRYSIYIANYAYGNVGPDALIEMDPEASDLSRGILALRDVAAEAGVSKYTGGRGVSVGPILSSSASDIFCDNENGPNFLFHNRGDGTFVDAAASAGVDDPHQHGRGVALADFNRDGKVDIVYGNWNGPHRLYLQMSAHGKVRFRDIASPKFSMPSPVRTVIAADFDNDQELEVFFNNFAHRSSSANRLFRVIHREHGDPLIEELNPGDALEPEGRGTGGVVTDFDGDGMLDLILSHGESMAQPLSVFRGNQGFSNNWLRVVPRTRFGAFARGAKVVLYTKKSGAHLRIIDGGSGYLCEMEPVAHFGLGKDEASSVEVTWPDGKMASRNVASSEMNSVLEIPYPRDDDRPQDPASLECGQGFSQQENGHCADTNECIQFPFVCPRDKPVCVNTYGSYRCRTNKRCSRGYEPNEDGTACVGTLGQSPAPRPTAPTTAAAAAAAATAARAAAAAPVLVDGDLDLGVKEGCK", "length": 656, "header": "tr|F1MFI4-1|F1MFI4_BOVIN Isoform 1 of Cartilage acidic protein 1 OS=Bos taurus OX=9913 GN=CRTAC1 PE=4 SV=4 CANONICAL=F1MFI4-1" }, "locus": { "chromosome": "26", "start_pos": 19170684, "end_pos": 19004535, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000010659.7", "url": "https://www.ensembl.org/id/ENSBTAT00000010659.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000010659.7", "url": "https://www.ensembl.org/id/ENSBTAP00000010659.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F1MFI4", "url": "https://www.uniprot.org/uniprotkb/F1MFI4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "F1MFI4", "url": "https://www.uniprot.org/uniprotkb/F1MFI4" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "F1MFI4", "url": "https://www.uniprot.org/uniprotkb/F1MFI4" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "F1MFI4", "url": "https://www.uniprot.org/uniprotkb/F1MFI4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of synapse assembly", "id": "GO:0051963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051963", "evidence": [ { "database": "UniProtKB", "id": "F1MFI4", "url": "https://www.uniprot.org/uniprotkb/F1MFI4" } ], "pmid": "" }, { "name": "axonal fasciculation", "id": "GO:0007413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007413", "evidence": [ { "database": "UniProtKB", "id": "F1MFI4", "url": "https://www.uniprot.org/uniprotkb/F1MFI4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1MFI4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 656, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1MFI4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1MFI4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1MFI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFI4" }, { "id": "SM00179", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00179" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like calcium-binding", "eco_id": "ECO_0000259", "start_pos": 559, "end_pos": 606, "start_aa": "Asp", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1MI51-1", "uniprot_ac": "F1MI51", "uniprot_id": "F1MI51_BOVIN", "mass": { "chemical_mass": 108366.0, "monoisotopic_mass": 108366.0 }, "refseq": { "ac": "XP_002690456", "name": "SUMO-interacting motif-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002690456" }, "gene_names": [ { "name": "SIMC1", "type": "recommended", "evidence": [ { "id": "F1MI51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI51" } ] }, { "name": "SIMC1", "type": "synonym", "evidence": [ { "id": "XP_002690456", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002690456" } ] } ], "protein_names": [ { "name": "SUMO interacting motifs containing 1", "type": "synonym", "evidence": [ { "id": "F1MI51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI51/entry#names_and_taxonomy" } ] }, { "name": "SUMO-interacting motif-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002690456", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002690456" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1MI51", "url": "https://www.uniprot.org/uniprotkb/F1MI51" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SIMC1", "url": "https://www.uniprot.org/uniprotkb/F1MI51", "locus": { "chromosome": "10", "start_pos": 5025395, "end_pos": 5109596, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000034998", "url": "https://www.ensembl.org/id/ENSBTAG00000034998" } ] } } ], "crossref": [ { "id": "F1MI51", "url": "https://alphafold.ebi.ac.uk/entry/F1MI51", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000034998", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000034998", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100336733", "url": "https://www.ncbi.nlm.nih.gov/gene/100336733", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR052119", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052119", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100336733", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100336733", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VMQSPRD", "url": "https://omabrowser.org/oma/group/VMQSPRD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1MI51", "url": "https://www.orthodb.org/?gene=F1MI51", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23187", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23187", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23187:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23187:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_002690456", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002690456", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPE6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPE6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MI51", "url": "https://www.uniprot.org/uniprotkb/F1MI51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MI51-1", "url": "https://www.uniprot.org/uniprotkb/F1MI51-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDFIVISDDSGSESSGGTRPSRARRLRRALSRTPGALPRRTVDFIDLTRETRPRAKDRSGLCVIDLTGSEEENRPIATLDLTLEPVAPSQKEPASLQACASLCSKETVEGWVDRSSRPAARRVINSDPVDLDLLEETAFEGPQPPMSISGDSVYPVEPNCSSTIFKGDLSFLASLQPSSNIHSLPQTSNNSSSSNQRIPLPCPQQDVPYPPQALPCPLQALPCPLQALPCPPRASSCPPRALSCPSQTMQYQLQTLSRLPQEELCPPQDMAYPQNVPGPQQGMPSPPHGSSWHPQRSLSPPQHSLGPPQDAPAPPQKISYLEDVSHLQDVPQSLEDMPQTPQDMPQSSGDMPLSPVSIPQSPRDMPPSLVSMPQPPADVSQSPVNAPPSPGDASPSPGDVPPSPGDAPPSPASVPHSSREVSCLSGDALRSPGDMSRSLVDMPPTVGQLAHLPKIRPASPQNDIQNHDTPMDVSAPSSPSSSPSPQSPEFETSLEKVPWLSVTENPARKERSLSEPVNPGCALIQTQIPQGGLYNRPCLHRLKYFLRPPVHHLFFQTLIPDKDTRENKGQKLEPIPHRRLRMVTNTIEENFPLGTVQFLMDFVSPQHYPPREIVAHIIQKILLSGSETLDVLKEAYMLLMKIQQLHPANAKTVEWDWKLLAYVMEEEGQNLPGRVFFLRYVVQTLEDDFQQILRKQRQHLQQAIASTVLSCDKQPHNVRDVIKWLIRAVTEDRLIQPPNENQTSPGKGILKTSSSHPSSQPNLTKNANQLIICQLQRMLSIAVEVDRTPTCSSNKIAEMMFGFVLDIPERSQREMFFTTMESHLLRCKVLEIIFLHSCETPTRLPLSLAQALYFLNHSTSLLKCQSDKTQWQKWDELVEHLQFLLSSYQHVLREHLRSSVIDRKDLIIKRIKPKPQQGDDISVVDVEKQIEAFRSRLVRMLGEPLVPQLQDKVHLLRLLLFFAADLNPDSEASP", "length": 975, "header": "tr|F1MI51-1|F1MI51_BOVIN Isoform 1 of SUMO interacting motifs containing 1 OS=Bos taurus OX=9913 GN=SIMC1 PE=4 SV=3 CANONICAL=F1MI51-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LPE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPE6/entry", "sequence": { "sequence": "MEDFIVISDDSGSESSGGTRPSRARRLRRALSRTPGALPRRTVDFIDLTRETRPRAKDRSGLCVIDLTGSEEENRPIATLDLTLEPVAPSQKEPASLQACASLCSKETVEGWVDRSSRPAARRVINSDPVDLDLLEETAFEGPQPPMSISGDSVYPVEPNCSSTIFKGDLSFLASLQPSSNIHSLPQTSNNSSSSNQRIPLPCPQQDVPYPPQALPCPLQALPCPLQALPCPPRASSCPPRALSCPSQTMQYQLQTLSRLPQEELCPPQDMAYPQNVPGPQQGMPSPPHGSSWHPQRSLSPPQHSLGPPQDAPAPPQKISYLEDVSHLQDVPQSLEDMPQTPQDMPQSSGDMPLSPVSIPQSPRDMPPSLVSMPQPPADVSQSPVNAPPSPGDASPSPGDVPPSPGDAPPSPASVPHSSREVSCLSGDALRSPGDMSRSLVDMPPTVGQLAHLPKIRPASPQNDIQNHDTPMDVSAPSSPSSSPSPQSPEFETSLEKVPWLSVTENPARKERSLSEPVNPGCALIQTQIPQGGLYNRPCLHRLKYFLRPPVHHLFFQTLIPDKDTRENKGQKLEPIPHRRLRMVTNTIEENFPLGTVQFLMDFVSPQHYPPREIVAHIIQKILLSGSETLDVLKEAYMLLMKIQQLHPANAKTVEWDWKLLAYVMEEEGQNLPGRVFFLRYVVQTLEDDFQQILRKQRQHLQQAIASTVLSCDKQPHNVRDVIKWLIRAVTEDRLIQPPNENQTSPGKGILKTSSSHPSSQPNLTKNANQLIICQLQRMLSIAVEVDRTPTCSSNKIAEMMFGFVLDIPERSQREMFFTTMESHLLRCKVLEIIFLHSCETPTRLPLSLAQALYFLNHSTSLLKCQSDKTQWQKWDELVEHLQFLLSSYQHVLRVQLQETRKDIAGIAALKEKNSHSIFVTVHMTVVLTVLSVV", "length": 934, "header": "tr|A0A3Q1LPE6-1|F1MI51_BOVIN Computationally mapped isoform of SUMO interacting motifs containing 1 OS=Bos taurus OX=9913 GN=SIMC1 PE=4 SV=2 CANONICAL=F1MI51-1" }, "locus": { "chromosome": "10", "start_pos": 5109397, "end_pos": 5040048, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077309.2", "url": "https://www.ensembl.org/id/ENSBTAT00000077309.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058882.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058882.2" } ] } }, { "isoform_ac": "F1MI51-1", "url": "https://www.uniprot.org/uniprotkb/F1MI51/entry", "sequence": { "sequence": "MEDFIVISDDSGSESSGGTRPSRARRLRRALSRTPGALPRRTVDFIDLTRETRPRAKDRSGLCVIDLTGSEEENRPIATLDLTLEPVAPSQKEPASLQACASLCSKETVEGWVDRSSRPAARRVINSDPVDLDLLEETAFEGPQPPMSISGDSVYPVEPNCSSTIFKGDLSFLASLQPSSNIHSLPQTSNNSSSSNQRIPLPCPQQDVPYPPQALPCPLQALPCPLQALPCPPRASSCPPRALSCPSQTMQYQLQTLSRLPQEELCPPQDMAYPQNVPGPQQGMPSPPHGSSWHPQRSLSPPQHSLGPPQDAPAPPQKISYLEDVSHLQDVPQSLEDMPQTPQDMPQSSGDMPLSPVSIPQSPRDMPPSLVSMPQPPADVSQSPVNAPPSPGDASPSPGDVPPSPGDAPPSPASVPHSSREVSCLSGDALRSPGDMSRSLVDMPPTVGQLAHLPKIRPASPQNDIQNHDTPMDVSAPSSPSSSPSPQSPEFETSLEKVPWLSVTENPARKERSLSEPVNPGCALIQTQIPQGGLYNRPCLHRLKYFLRPPVHHLFFQTLIPDKDTRENKGQKLEPIPHRRLRMVTNTIEENFPLGTVQFLMDFVSPQHYPPREIVAHIIQKILLSGSETLDVLKEAYMLLMKIQQLHPANAKTVEWDWKLLAYVMEEEGQNLPGRVFFLRYVVQTLEDDFQQILRKQRQHLQQAIASTVLSCDKQPHNVRDVIKWLIRAVTEDRLIQPPNENQTSPGKGILKTSSSHPSSQPNLTKNANQLIICQLQRMLSIAVEVDRTPTCSSNKIAEMMFGFVLDIPERSQREMFFTTMESHLLRCKVLEIIFLHSCETPTRLPLSLAQALYFLNHSTSLLKCQSDKTQWQKWDELVEHLQFLLSSYQHVLREHLRSSVIDRKDLIIKRIKPKPQQGDDISVVDVEKQIEAFRSRLVRMLGEPLVPQLQDKVHLLRLLLFFAADLNPDSEASP", "length": 975, "header": "tr|F1MI51-1|F1MI51_BOVIN Isoform 1 of SUMO interacting motifs containing 1 OS=Bos taurus OX=9913 GN=SIMC1 PE=4 SV=3 CANONICAL=F1MI51-1" }, "locus": { "chromosome": "10", "start_pos": 5109397, "end_pos": 5026399, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020753.7", "url": "https://www.ensembl.org/id/ENSBTAT00000020753.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020753.6", "url": "https://www.ensembl.org/id/ENSBTAP00000020753.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100336733", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100336733", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E9Q6E9-1", "protein_name": "SUMO-interacting motif-containing protein 1", "gene_name": "Simc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDFIVISDDSGSESSAGTRSGRARRLRRALSRTPGALPRRTVDFIDLTRENRARTKDRNGLCVIDLTRNEEENRPIATLDLTLEPVASSQKEPTSLQTCTSLSGKEVMEAHEDRGSQPAAQRIINNDPVDLDLLEENLFEGSRPPTSISQDSVYPPEPNCSSITYKGDLSFLTSLQLSSDVSSFSSTSNQRASLPCPQQDVPCQSQGLLCPLQALSCPQTASPCPPRASSCPPQALSCPPQALSCPSQTLQCQLQALPQPPQEVPCSTQNVPCPQQNMPSTPQGLSWHPRHTLYPYQDTLGLPQDVPGRPQNMSYPQDVTQLQDMPWSLHDMPLSLQDVLQSLQDVPPLLGDVPPSPEVMQLPGYVTQTSRDVIQSPAGVTQSLGSMMQSPGSVTQSLRSVMQSSGSVTQSLRSVMQSSGSVTQSLRSVMQSSGSVMQSPGGVTQSLRSVTQSPGGVMQSPGGVMQSPRDVMQSPRDVMQSPRDVMQSPRGVTQSLGSMMQSPGGVMQSLRSVMQSSGGVTQSLRSVMQSPGGVMQSPGGVTQSPRGMIKSPGMMLSPGDVIQSLNSVPQSSRDRMQSAGHVPSASGDAIQSPGGMSPTSRDRMQSPGGVSLATEDSIQLPGGVPLSSDVIQSQGGVPLSSKDRMQSPGGVPPSSGDMIQSQGGVPQSLGDAIQSAGGVPQSSGDAIQSPGGVSLATGDSIQLPGGVPLSSGDVIQSQGGVPRSSRDRMQSPGGVPPSSGGVIQSPGGVSPASGDAIQSPGSVLPASGDAIQSAGGVLLASGDAIQSPRSVPQSPSGTLRSPGNMSESLGDTPNLSGDVSNSPQALLDLARDRPKSSPNDVQNRDTPMDISASSSSSCSANPQSRQSEFKLDKVPWLTITDSSARREKSLPQLANPGSAQIQGQIPQVGVYNRPCLHRLKYFLRPPVHHLFFQTLIPDKDTRESKGQKLEPIPHRRLRMVTNTIEENFPLGTVQFLMDFVSPQHYPPREIVAHIVQKILLSGSETVDVLKEAYMLLMKIQQLHPANAKTVEWDWKLLTYVMEEEGQTLPGRVLFLRYVVQTLEDDFQQILRRQRQHLQQSIANTVLSCDKQPHNVRDVIKWLVKAVTENELTPPQDETQTSPRTGVLKTSSDHLSPRPNQNKNTNQLIVCQLQRMLSIAVEVDRTPTCSSNKIAEMMFGFVLDIPERSQREMFFTTMESHLLRCKVLEIIFLHSCETPTRLPLSLAQTLYFLNNSTSLLKCQSDKTQWQTWDELVEHLQFLLSSYQHVLREHLRSSVIDRKDLIIKRIKPKPQQGDDITVLDVEKQIEAFRSRLVHILGEPLVPQLQDKVHLLKLLLFYAADLNPDTEPASEH", "length": 1354 }, "evidence": [ { "id": "F1MI51", "url": "https://omabrowser.org/oma/group/F1MI51/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LWT0-1", "protein_name": "SUMO-interacting motif-containing protein 1", "gene_name": "Simc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDFIVISDDSGSESSAGTRSGRARRLRRALSRTPGALPRRTVDFIDLTRETRTRAKDRNGLCVIDLTRSEEENRPIATLDLTLEPVASSQKEPPSLQTCTNLSGKEMIEAQGDRGTQPAAQRVINNDPVDLDLLEENMFEGSRPPTSISQDSVYPPEPNCSSITYKGDLSFLTSLQLSSDVSPFSSTSNNSSSSSNQRTSLPCPQQDVPCQSQGLLCSLQALSYPLRGSPCPPRASSCPPQALSCPPQALSSLSCPSQTVQCQLQALPQPPQEVPCSTQNVPCPQQNIPSTPQDLPWHPRHPLYPSQDTLGLPQDVPGRPQNVSYPQDMTQLQDMPWSLQDMPLSLQDVLQSLQDVPPLLGDVPQSPEVMQLPGYMTQSSRNVIQSSAGVIRSSGGVMQPSGCMMQPSGGVTQSLRSAIQSSGGVMQSSGVTQSLRSVMQSSGGVMQSSGVTQSSGGVTWSLRSVMQSSGCMMQSPGGVMLSAGDMMQSSGGATRSLRSMMQSSGCMMQSPGGVTQSSGSVMQSLRNVIQSSGGVTQSSGGVIQSSSGVPQSLRDRMQSPGSVSQSSGDVIQSPRGASPASGDVIKSQGGMPRSLRDRMQSPGGVPQSSEDVIQSAGGVSPASGDAIQSPGGVSPASGDAMQSSGGVTPSLGDVPQSSGGVSPASGDAMQSPGGVTPSLGDAMQSPGGVSPASGDAMQSPGGVSPSLGDVPQSPGNMLESLGNTPNLSGDVSHVPQELLDLAKGRPKLSLNAVQNRHSPMTISAPSSPSCSANPLSQQSEFSSEKRPWLTVSNSSAREERSLPQSATPGSAQIQGQIAQAGVYNRPCLHRLKYFLRPPVHHLFFQTLIPDKDTRESKGQKLEPIPHRRLRMVTNTIEENFPLGTVQFLMDFVSPQHYPPREIVAHIIQKILLSGSETVDVLKEAYMLLMKIQQLHPANAKTVEWDWKLLTYVMEEEGQTLPGRVLFLRYVVQTLEDDFQQILRRQRQHLQQSIANTVLSCDKQPHNVRDVIKWLVKAVTENALTPPQDETQTSPGPGVLKTSSDHLSPQPNLARNTNQLIVCQLQRMLSIAVEVDRTPTCSSNKIAEMMFGFVLDIPERSQREMFFTTMESHLLRCKVLEIIFLHSCETPTRLPLSLAQALYFLNNSTSLLKCQSDKSQWQTWDELVEHLQFLLSSYQHVLREHLRSSVIDRKDLIIKRIKPKPQQGDDITVVDVEKQIEAFRSRLVHILGEPLVPQLQDKVHLLKLLLFYAADLNPDTEPASER", "length": 1266 }, "evidence": [ { "id": "F1MI51", "url": "https://omabrowser.org/oma/group/F1MI51/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8NDZ2-1", "protein_name": "SUMO-interacting motif-containing protein 1", "gene_name": "SIMC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPASASGEDLRKLPTMAEVNGEQDFIDLTRETRPRTKDRSGLYVIDLTRAEGENRPIATLDLTLEPVTPSQKEPTSLQTCASLSGKAVMEGHVDRSSQPTARRIINSDPVDLDLVEENTFVGPPPATSISGGSVYPTEPNCSSATFTGNLSFLASLQLSSDVSSLSPTSNNSRSSSSSSNQKAPLPCPQQDVSRPPQALPCPLRPLPCPPRASPCPPRASSCPPRALSCPSQTMQCQLPALTHPPQEVPCPRQNIPGPPQDSLGLPQDVPGLPQSILHPQDVAYLQDMPRSPGDVPQSPSDVSPSPDAPQSPGGMPHLPGDVLHSPGDMPHSSGDVTHSPRDIPHLPGDRPDFTQNDVQNRDMPMDISALSSPSCSPSPQSETPLEKVPWLSVMETPARKEISLSEPAKPGSAHVQSRTPQGGLYNRPCLHRLKYFLRPPVHHLFFQTLIPDKDTRENKGQKLEPIPHRRLRMVTNTIEENFPLGTVQFLMDFVSPQHYPPREIVAHIIQKILLSGSETVDVLKEAYMLLMKIQQLHPANAKTVEWDWKLLTYVMEEEGQTLPGRVLFLRYVVQTLEDDFQQTLRRQRQHLQQSIANMVLSCDKQPHNVRDVIKWLVKAVTEDGLTQPPNGNQTSSGTGILKASSSHPSSQPNLTKNTNQLIVCQLQRMLSIAVEVDRTPTCSSNKIAEMMFGFVLDIPERSQREMFFTTMESHLLRCKVLEIIFLHSCETPTRLPLSLAQALYFLNNSTSLLKCQSDKSQWQTWDELVEHLQFLLSSYQHVLREHLRSSVIDRKDLIIKRIKPKPQQGDDITVVDVEKQIEAFRSRLIQMLGEPLVPQLQDKVHLLKLLLFYAADLNPDAEPFQKGWSGS", "length": 872 }, "evidence": [ { "id": "F1MI51", "url": "https://omabrowser.org/oma/group/F1MI51/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "peptidase inhibitor activity", "id": "GO:0030414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030414", "evidence": [ { "database": "UniProtKB", "id": "F1MI51", "url": "https://www.uniprot.org/uniprotkb/F1MI51" } ], "pmid": "" }, { "name": "SUMO polymer binding", "id": "GO:0032184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032184", "evidence": [ { "database": "UniProtKB", "id": "F1MI51", "url": "https://www.uniprot.org/uniprotkb/F1MI51" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "sarcomere", "id": "GO:0030017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030017", "evidence": [ { "database": "UniProtKB", "id": "F1MI51", "url": "https://www.uniprot.org/uniprotkb/F1MI51" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "F1MI51", "url": "https://www.uniprot.org/uniprotkb/F1MI51" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 742, "end_pos": 744, "annotation": "n_glycosylation_sequon" }, { "start_pos": 763, "end_pos": 765, "annotation": "n_glycosylation_sequon" }, { "start_pos": 857, "end_pos": 859, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1MI51-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 975, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1MI51-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1MI51" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 160, "end_pos": 162 }, { "start_pos": 190, "end_pos": 192 }, { "start_pos": 191, "end_pos": 193 }, { "start_pos": 742, "end_pos": 744 }, { "start_pos": 763, "end_pos": 765 }, { "start_pos": 857, "end_pos": 859 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1MBS9-1", "uniprot_ac": "F1MBS9", "uniprot_id": "F1MBS9_BOVIN", "mass": { "chemical_mass": 71640.0, "monoisotopic_mass": 71640.0 }, "refseq": {}, "gene_names": [ { "name": "CDC40", "type": "recommended", "evidence": [ { "id": "F1MBS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBS9" } ] } ], "protein_names": [ { "name": "Pre-mRNA-processing factor 17", "type": "recommended", "evidence": [ { "id": "F1MBS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBS9/entry#names_and_taxonomy" } ] }, { "name": "Cell division cycle 40 homolog", "type": "synonym", "evidence": [ { "id": "F1MBS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBS9/entry#names_and_taxonomy" } ] }, { "name": "PRP17 homolog", "type": "synonym", "evidence": [ { "id": "F1MBS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBS9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1MBS9", "url": "https://www.uniprot.org/uniprotkb/F1MBS9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CDC40", "url": "https://www.uniprot.org/uniprotkb/F1MBS9", "locus": { "chromosome": "9", "start_pos": 39988950, "end_pos": 40037607, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000409", "url": "https://www.ensembl.org/id/ENSBTAG00000000409" } ] } } ], "crossref": [ { "id": "F1MBS9", "url": "https://alphafold.ebi.ac.uk/entry/F1MBS9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000409", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000409", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032847", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032847", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LQ78", "url": "https://www.orthodb.org/?gene=A0A3Q1LQ78", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MBS9", "url": "https://www.orthodb.org/?gene=F1MBS9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43979", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43979", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43979:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43979:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-159236", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-159236", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LQ78", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQ78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LQ78-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQ78-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MBS9", "url": "https://www.uniprot.org/uniprotkb/F1MBS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MBS9-1", "url": "https://www.uniprot.org/uniprotkb/F1MBS9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNQPFRGGVKEGPACPAPPLAPNYNPHGASSTSRRAARRECSTWRPQGPGLHRLSVAVMSAAIAALAASYGSGSGSESDSDSEGGRCSLPAADSLMHLTKSSSDKPSLAVAVDSAPEVAVKEDLETGVHLDPAVKEVQYNPTYETMFAPEFGPENPFRTQQMAAPRNMLSGYAEPAHINDFMFEQQRRTFATYGYALDPSLDNHQVSTKYIGSVEEAEKNQGLTVFETGQKKIEKRKKFKENDASNIDGFLGPWAKYVDEKDVAKPSEEEQKELDEITAKRQKKGKQEEEKPGEEKTILHVKEMYDYQGRSYLHIPQDVGVNLRSTVPPEKCYLPKKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGDRRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKVCIGAVWHPHETSKVITCGWDGLIKLWD", "length": 637, "header": "tr|F1MBS9-1|F1MBS9_BOVIN Isoform 1 of Pre-mRNA-processing factor 17 OS=Bos taurus OX=9913 GN=CDC40 PE=4 SV=2 CANONICAL=F1MBS9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LQ78-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQ78/entry", "sequence": { "sequence": "MDCSLPGVHGIFQATFHLLEDLETGVHLDPAVKEVQYNPTYETMFAPEFGPENPFRTQQMAAPRNMLSGYAEPAHINDFMFEQQRRTFATYGYALDPSLDNHQVSTKYIGSVEEAEKNQGLTVFETGQKKIEKRKKFKENDASNIDGFLGPWAKYVDEKDVAKPSEEEQKELDEITAKRQKKGKQEEEKPGEEKTILHVKEMYDYQGRSYLHIPQDVGVNLRSTVPPEKCYLPKKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGDRRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKVCIGAVWHPHETSKVITCGWDGLIKLWD", "length": 535, "header": "tr|A0A3Q1LQ78-1|F1MBS9_BOVIN Computationally mapped isoform of Pre-mRNA-processing factor 17 OS=Bos taurus OX=9913 GN=CDC40 PE=4 SV=2 CANONICAL=F1MBS9-1" }, "locus": { "chromosome": "9", "start_pos": 40028973, "end_pos": 39990722, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086664.2", "url": "https://www.ensembl.org/id/ENSBTAT00000086664.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059117.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059117.2" } ] } }, { "isoform_ac": "F1MBS9-1", "url": "https://www.uniprot.org/uniprotkb/F1MBS9/entry", "sequence": { "sequence": "MNQPFRGGVKEGPACPAPPLAPNYNPHGASSTSRRAARRECSTWRPQGPGLHRLSVAVMSAAIAALAASYGSGSGSESDSDSEGGRCSLPAADSLMHLTKSSSDKPSLAVAVDSAPEVAVKEDLETGVHLDPAVKEVQYNPTYETMFAPEFGPENPFRTQQMAAPRNMLSGYAEPAHINDFMFEQQRRTFATYGYALDPSLDNHQVSTKYIGSVEEAEKNQGLTVFETGQKKIEKRKKFKENDASNIDGFLGPWAKYVDEKDVAKPSEEEQKELDEITAKRQKKGKQEEEKPGEEKTILHVKEMYDYQGRSYLHIPQDVGVNLRSTVPPEKCYLPKKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGDRRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKVCIGAVWHPHETSKVITCGWDGLIKLWD", "length": 637, "header": "tr|F1MBS9-1|F1MBS9_BOVIN Isoform 1 of Pre-mRNA-processing factor 17 OS=Bos taurus OX=9913 GN=CDC40 PE=4 SV=2 CANONICAL=F1MBS9-1" }, "locus": { "chromosome": "9", "start_pos": 40037408, "end_pos": 39990722, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000526.7", "url": "https://www.ensembl.org/id/ENSBTAT00000000526.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000526.6", "url": "https://www.ensembl.org/id/ENSBTAP00000000526.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-159236", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-159236", "resource": "Reactome", "description": "Transport of Mature mRNA derived from an Intron-Containing Transcript" }, { "id": "R-BTA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-BTA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "F1MBS9", "url": "https://www.uniprot.org/uniprotkb/F1MBS9" } ], "pmid": "" }, { "name": "embryonic brain development", "id": "GO:1990403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990403", "evidence": [ { "database": "UniProtKB", "id": "F1MBS9", "url": "https://www.uniprot.org/uniprotkb/F1MBS9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "F1MBS9", "url": "https://www.uniprot.org/uniprotkb/F1MBS9" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": 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"overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1MBS9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1MBS9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", 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"MALRPGSGAGGGGAAGAGTGAAGGGSFMFPVASGLRPPQAGLMPMQQQGFPMVSVMQPNMQGMIGMNYSSQMSQGPIAMQAGIPMGPIPAGGMPYLGQAPFLGMRPPGPQYTPDMQKQFAEEQQKRFEQQQKLLEEERKRRQFEEQKQKLRLLSSVKPKTGEKSRDDALEAIKGNLDGFSRDAKMHPTPASHPKKPDYPTSSHSTKTVSPSPAFLDEEEFSDFMQGPVEVPTCGPSSTSQPFQSFHSTTPLGQLHVQKAGAQPLPPGSSLEEKLLVSCDLSTSGQEQIKFNTSEVGHKALGPGSSKNHPSLMASNGGAVDGRVSGTTTAEAAKTSDQNLCIEESGVGVFPSQDPVQPRMPPWIYNESLVPDAYKKILETTMTPTGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYAVLAMIAATQRGVPAMSPDALNQFPAAPVPTLSGFPVTLPAAVSQPTGMPSGPAGSMPLTLGQPVMGINLVGPVGGAAAQASSGFMSAYAANQVVKPEDDDFQDFQDASKSGSLDDSFSDFQELPASSKSNNSQHGNSAPSLLMPLPGTKASASMDKYAVFKGIAADKPSENTVPFGEPGDKYSAFRELEQTAENKSLGENFAEFRSAGTDDGFTDFKTADSISPLEPPAKDKPFPATFPSGATQQKPQTQVKNPLNLADLDMFSSVTCSNEKPLSFSAAFSVSKPVSTRPQPAGSAAPSAALVSTKTAGLADDFGEFNLFGEYSSPASVGEQDDFADFMAFSNSSVSSEQKADDKYEALKEEASPGPLTSSTGIAGKSGQNSAATSTKYDVFKQLSLEGSGLGGEELKDSTSSGKSDDDFADFHSSKFSSVNSDKSLGEKAVAFRHTKEDSASVKSLDLPSLGGSSVGKEDSEDALSVQFDMKLADVGGELKHVMSDSSLDLPTVSGQHPPAADIEDLKYAAFGTYSSSFAVSTLTSSDWSDRDDASQGRKLSPFVLSAGSGASAAASVLQKKETSFGSSENLTVASLSKVTTFASEDPLPETTFLPFANFKDVIPQASEPKEYESGDFRDFARQDLPVGERSQEAMCLSPASSSASHDTPKECTDDFGEFQSEKPKISKFDFLVANSQGKMKSSEEMIKNELATFDLSVQGSHKRSLSLGDKEISRSSPSPALEQPFRDRSNTLSEKPALPVIRDKYKDLTGEVEENERYAYEWQRCLGSALEVIKKANDTLNGISSSSVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQQLLKDIDKVWNNLIGFMSLATLTPDENSLDFSSCMLRPGIKNAQELACGVCLLNVDSRSRKEEKPAEEHPKKAFNSETDSFKLAYGGHQYHASCANFWINCVEPKPPGLILPDLL", "length": 1385, "header": "tr|F1MI41-1|F1MI41_BOVIN Isoform 1 of Synergin gamma OS=Bos taurus OX=9913 GN=SYNRG PE=4 SV=2 CANONICAL=F1MI41-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LQK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQK6/entry", "sequence": { "sequence": "MALRPGSGAGGGGAAGAGTGAAGGGSFMFPVASGLRPPQAGLMPMQQQGFPMVSVMQPNMQGMIGMNYSSQMSQGPIAMQAGIPMGPIPAGGMPYLGQAPFLGMRPPGPQYTPDMQKQFAEEQQKRFEQQQKLLEEERKRRQFEEQKQKLRLLSSVKPKTGEKSRDDALEAIKGNLDGFSRDAKMHPTPASHPKKPGVGVFPSQDPVQPRMPPWIYNESLVPDAYKKILETTMTPTGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYAVLAMIAATQVVKPEDDDFQDFQDASKSGSLDDSFSDFQELPASSKSNNSQHGNSAPSLLMPLPGTKASASMDKYAVFKGIAADKPSENTVPFGEPGDKYSAFRELEQTAENKSLGENFAEFRSAGTDDGFTDFKTADSISPLEPPAKDKPFPATFPSGATQQKPQTQVKNPLNLADLDMFSSVTCSNEKPLSFSAAFSVSKPVSTRPQPAGSAAPSAALVSTKTAGLADDFGEFNLFGEYSSPASVGEQDDFADFMAFSNSSVSSEQKADDKYEALKEEASPGPLTSSTGIAGKSGQNSAATSTKYDVFKQLSLEGSGLGGEELKDSTSSGKSDDDFADFHSSKFSSVNSDKSLGEKAVAFRHTKEDSASVKSLDLPSLGGSSVGKEDSEDALSVQFDMKLADVGGELKHVMSDSSLDLPTVSGQHPPAAAGSGASAAASVLQKKETSFGSSENLTVASLSKVTTFASEDPLPETTFLPFANFKDVIPQASEPKEYESGDFRDFARQDLPVGERSQEAMCLSPASSSASHDTPKECTDDFGEFQSEKPKISKFDFLVANSQGKMKSSEEMIKNELATFDLSVQGSHKRSLSLGDKEISRSSPSPALEQPFRDRSNTLSEKPALPVIRDKYKDLTGEVEENERYAYEWQRCLGSALEVIKKANDTLNGISSSSVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQQLLKDIDKVWNNLIGFMSLATLTPDENSLDFSSCMLRPGIKNAQELACGVCLLNVDSRSRKEEKPAEEHPKKAFNSETDSFKLAYGGHQYHASCANFWINCVEPKPPGLILPDLL", "length": 1109, "header": "tr|A0A3Q1LQK6-1|F1MI41_BOVIN Computationally mapped isoform of Synergin gamma OS=Bos taurus OX=9913 GN=SYNRG PE=4 SV=3 CANONICAL=F1MI41-1" }, "locus": { "chromosome": "19", "start_pos": 13895850, "end_pos": 13812909, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081179.3", "url": "https://www.ensembl.org/id/ENSBTAT00000081179.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059276.3", "url": "https://www.ensembl.org/id/ENSBTAP00000059276.3" } ] } }, { "isoform_ac": "A0A3Q1LQS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQS1/entry", "sequence": { "sequence": "MSWISNMCFMFPVASGLRPPQAGLMPMQQQGFPMVSVMQPNMQGMIGMNYSSQMSQGPIAMQAGIPMGPIPAGGMPYLGQAPFLGMRPPGPQYTPDMQKQFAEEQQKRFEQQQKLLEEERKRRQFEEQKQKLRLLSSVKPKTGEKSRDDALEAIKGNLDGFSRDAKMHPTPASHPKKPDYPTSSHSTKTVSPSPAFLDEEEFSDFMQGPVEVPTCGPSSTSQPFQSFHSTTPLGQLHVQKAGAQPLPPGVGVFPSQDPVQPRMPPWIYNESLVPDAYKKILETTMTPTGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYAVLAMIAATQRGVPAMSPDALNQFPAAPVPTLSGFPVTLPAAVSQPTGMPSGPAGSMPLTLGQPVMGINLVGPVGGAAAQASSGFMSAYAANQVVKPEDDDFQDFQDASKSGSLDDSFSDFQELPASSKSNNSQHGNSAPSLLMPLPGTKASASMDKYAVFKGIAADKPSENTVPFGEPGDKYSAFRELEQTAENKSLGENFAEFRSAGTDDGFTDFKTADSISPLEPPAKDKPFPATFPSGATQQKPQTQVKNPLNLADLDMFSSVTCSNEKPLSFSAAFSVSKPVSTRPQPAGSAAPSAALVSTKTAGLADDFGEFNLFGEYSSPASVGEQDDFADFMAFSNSSVSSEQKADDKYEALKEEASPGPLTSSTGIAGKSGQNSAATSTKYDVFKQLSLEGSGLGGEELKDSTSSGKSDDDFADFHSSKFSSVNSDKSLGEKAVAFRHTKEDSASVKSLDLPSLGGSSVGKEDSEDALSVQFDMKLADVGGELKHVMSDSSLDLPTVSGQHPPAADIEDLKYAAFGTYSSSFAVSTLTSSDWSDRDDASQGRKLSPFVLSAGSGASAAASVLQKKETSFGSSENLTVASLSKVTTFASEDPLPETTFLPFANFKDVIPQASEPKEYESGDFRDFARQDLPVGERSQEAMCLSPASSSASHDTPKECTDDFGEFQSEKPKISKFDFLVANSQGKMKSSEEMIKNELATFDLSVQGSHKRSLSLGDKEISRSSPSPALEQPFRDRSNTLSEKPALPVIRDKYKDLTGEVEENERYAYEWQRCLGSALEVIKKANDTLNGISSSSVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQQLLKDIDKVWNNLIGFMSLATLTPDENSLDFSSCMLRPGIKNAQELACGVCLLNVDSRSRAFNSETDSFKLAYGGHQYHASCANFWINCVEPKPPGLILPDLL", "length": 1277, "header": "tr|A0A3Q1LQS1-1|F1MI41_BOVIN Computationally mapped isoform of Synergin gamma OS=Bos taurus OX=9913 GN=SYNRG PE=4 SV=2 CANONICAL=F1MI41-1" }, "locus": { "chromosome": "19", "start_pos": 13889903, "end_pos": 13812909, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072903.2", "url": "https://www.ensembl.org/id/ENSBTAT00000072903.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057352.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057352.2" } ] } }, { "isoform_ac": "A0A3Q1MI81-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI81/entry", "sequence": { "sequence": "MSWISNMCFMFPVASGLRPPQAGLMPMQQQGFPMVSVMQPNMQGMIGMNYSSQMSQGPIAMQAGIPMGPIPAGGMPYLGQAPFLGMRPPGPQYTPDMQKQFAEEQQKRFEQQQKLLEEERKRRQFEEQKQKLRLLSSVKPKTGEKSRDDALEAIKGNLDGFSRDAKMHPTPASHPKKPDYPTSSHSTKTVSPSPAFLDEEEFSDFMQGPVEVPTCGPSSTSQPFQSFHSTTPLGQLHVQKAGAQPLPPGVGVFPSQDPVQPRMPPWIYNESLVPDAYKKILETTMTPTGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYAVLAMIAATQRGVPAMSPDALNQFPAAPVPTLSGFPVTLPAAVSQPTGMPSGPAGSMPLTLGQPVMGINLVGPVGGAAAQASSGFMSAYAANQVVKPEDDDFQDFQDASKSGSLDDSFSDFQELPASSKSNNSQHGNSAPSLLMPLPGTKASASMDKYAVFKGIAADKPSENTVPFGEPGDKYSAFRELEQTAENKSLGENFAEFRSAGTDDGFTDFKTADSISPLEPPAKDKPFPATFPSGATQQKPQTQVKNPLNLADLDMFSSVTCSNEKPLSFSAAFSVSKPVSTRPQPAGSAAPSAALVSTKTAGLADDFGEFNLFGEYSSPASVGEQDDFADFMAFSNSSVSSEQKADDKYEALKEEASPGPLTSSTGIAGKSGQNSAATSTKYDVFKQLSLEGSGLGGEELKDSTSSGKSDDDFADFHSSKFSSVNSDKSLGEKAVAFRHTKEDSASVKSLDLPSLGGSSVGKEDSEDALSVQFDMKLADVGGELKHVMSDSSLDLPTVSGQHPPAADIEDLKYAAFGTYSSSFAVSTLTSSDWSDRDDASQGRKLSPFVLSAGSGASAAASVLQKKETSFGSSENLTVASLSKVTTFASEDPLPETTFLPFANFKDVIPQASEPKEYESGDFRDFARQDLPVGERSQEAMCLSPASSSASHDTPKECTDDFGEFQSEKPKISKFDFLVANSQGKMKSSEEMIKNELATFDLSVQGSHKRSLSLGDKEISRSSPSPALEQPFRDRSNTLSEKPALPVIRDKYKDLTGEVEENERYAYEWQRCLGSALEVIKKANDTLNGISSSSVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQQLLKDIDKVWNNLIGFMSLATLTPDENSLDFSSCMLRPGIKNAQELACGVCLLNVDSRSRKEEKPAEEHPKKAFNSETDSFKLAYGGHQYHASCANFWINCVEPKPPGLILPDLL", "length": 1289, "header": "tr|A0A3Q1MI81-1|A0A3Q1MI81_BOVIN Computationally mapped isoform of Synergin gamma OS=Bos taurus OX=9913 GN=SYNRG PE=4 SV=2 CANONICAL=F1MI41-1" }, "locus": { "chromosome": "19", "start_pos": 13889903, "end_pos": 13812909, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076587.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076587.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074002.2", "url": "https://www.ensembl.org/id/ENSBTAP00000074002.2" } ] } }, { "isoform_ac": "A0A3Q1MIN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIN9/entry", "sequence": { "sequence": "MALRPGSGAGGGGAAGAGTGAAGGGSFMFPVASGLRPPQAGLMPMQQQGFPMVSVMQPNMQGMIGMNYSSQMSQGPIAMQAGIPMGPIPAGGMPYLGQAPFLGMRPPGPQYTPDMQKQFAEEQQKRFEQQQKLLEEERKRRQFEEQKQKLRLLSSVKPKTGEKSRDDALEAIKGNLDGFSRDAKMHPTPASHPKKPGSSLEEKLLVSCDLSTSGQEQIKFNTSEVGHKALGPGSSKNHPSLMASNGGAVDGRVSGTTTAEAAKTSDQNLCIEESGVGVFPSQDPVQPRMPPWIYNESLVPDAYKKILETTMTPTGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYAVLAMIAATQRGVPAMSPDALNQFPAAPVPTLSGFPVTLPAAVSQPTGMPSGPAGSMPLTLGQPVMGINLVGPVGGAAAQASSGFMSAYAANQVVKPEDDDFQDFQDASKSGSLDDSFSDFQELPASSKSNNSQHGNSAPSLLMPLPGTKASASMDKYAVFKGIAADKPSENTVPFGEPGDKYSAFRELEQTAENKSLGENFAEFRSAGTDDGFTDFKTADSISPLEPPAKDKPFPATFPSGATQQKPQTQVKNPLNLADLDMFSSVTCSNEKPLSFSAAFSVSKPVSTRPQPAGSAAPSAALVSTKTAGLADDFGEFNLFGEYSSPASVGEQDDFADFMAFSNSSVSSEQKADDKYEALKEEASPGPLTSSTGIAGKSGQNSAATSTKYDVFKQLSLEGSGLGGEELKDSTSSGKSDDDFADFHSSKFSSVNSDKSLGEKAVAFRHTKEDSASVKSLDLPSLGGSSVGKEDSEDALSVQFDMKLADVGGELKHVMSDSSLDLPTVSGQHPPAADIEDLKYAAFGTYSSSFAVSTLTSSDWSDRDDASQGRKLSPFVLSAGSGASAAASVLQKKETSFGSSENLTVASLSKVTTFASEDPLPETTFLPFANFKDVIPQASEPKEYESGDFRDFARQDLPVGERSQEAMCLSPASSSASHDTPKECTDDFGEFQSEKPKISKFDFLVANSQGKMKSSEEMIKNELATFDLSVQGSHKRSLSLGDKEISRSSPSPALEQPFRDRSNTLSEKPALPVIRDKYKDLTGEVEENERYAYEWQRCLGSALEVIKKANDTLNGISSSSVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQQLLKDIDKVWNNLIGFMSLATLTPDENSLDFSSCMLRPGIKNAQELACGVCLLNVDSRSRAFNSETDSFKLAYGGHQYHASCANFWINCVEPKPPGLILPDLL", "length": 1303, "header": "tr|A0A3Q1MIN9-1|A0A3Q1MIN9_BOVIN Computationally mapped isoform of Synergin gamma OS=Bos taurus OX=9913 GN=SYNRG PE=4 SV=2 CANONICAL=F1MI41-1" }, "locus": { "chromosome": "19", "start_pos": 13895850, "end_pos": 13812909, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076983.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076983.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070601.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070601.2" } ] } }, { "isoform_ac": "A0A3Q1MYN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MYN7/entry", "sequence": { "sequence": "MALRPGSGAGGGGAAGAGTGAAGGGSFMFPVASGLRPPQAGLMPMQQQGFPMVSVMQPNMQGMIGMNYSSQMSQGPIAMQAGIPMGPIPAGGMPYLGQAPFLGMRPPGPQYTPDMQKQFAEEQQKRFEQQQKLLEEERKRRQFEEQKQKLRLLSSVKPKTGEKSRDDALEAIKGNLDGFSRDAKMHPTPASHPKKPGVGVFPSQDPVQPRMPPWIYNESLVPDAYKKILETTMTPTGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYAVLAMIAATQRGVPAMSPDALNQFPAAPVPTLSGFPVTLPAAVSQPTGMPSGPAGSMPLTLGQPVMGINLVGPVGGAAAQASSGFMSAYAANQVVKPEDDDFQDFQDASKSGSLDDSFSDFQELPASSKSNNSQHGNSAPSLLMPLPGTKASASMDKYAVFKGIAADKPSENTVPFGEPGDKYSAFRELEQTAENKSLGENFAEFRSAGTDDGFTDFKTADSISPLEPPAKDKPFPATFPSGATQQKPQTQVKNPLNLADLDMFSSVTCSNEKPLSFSAAFSVSKPVSTRPQPAGSAAPSAALVSTKTAGLADDFGEFNLFGEYSSPASVGEQDDFADFMAFSNSSVSSEQKADDKYEALKEEASPGPLTSSTGIAGKSGQNSAATSTKYDVFKQLSLEGSGLGGEELKDSTSSGKSDDDFADFHSSKFSSVNSDKSLGEKAVAFRHTKEDSASVKSLDLPSLGGSSVGKEDSEDALSVQFDMKLADVGGELKHVMSDSSLDLPTVSGQHPPAADIEDLKYAAFGTYSSSFAVSTLTSSDWSDRDDASQGRKLSPFVLSAGSGASAAASVLQKKETSFGSSENLTVASLSKVTTFASEDPLPETTFLPFANFKDVIPQASEPKEYESGDFRDFARQDLPVGERSQEAMCLSPASSSASHDTPKECTDDFGEFQSEKPKISKFDFLVANSQGKMKSSEEMIKNELATFDLSVQGSHKRSLSLGDKEISRSSPSPALEQPFRDRSNTLSEKPALPVIRDKYKDLTGEVEENERYAYEWQRCLGSALEVIKKANDTLNGISSSSVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQQLLKDIDKVWNNLIGFMSLATLTPDENSLDFSSCMLRPGIKNAQELACGVCLLNVDSRSRAFNSETDSFKLAYGGHQYHASCANFWINCVEPKPPGLILPDLL", "length": 1225, "header": "tr|A0A3Q1MYN7-1|A0A3Q1MYN7_BOVIN Computationally mapped isoform of Synergin gamma OS=Bos taurus OX=9913 GN=SYNRG PE=4 SV=2 CANONICAL=F1MI41-1" }, "locus": { "chromosome": "19", "start_pos": 13895850, "end_pos": 13812909, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077558.2", "url": "https://www.ensembl.org/id/ENSBTAT00000077558.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061200.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061200.2" } ] } }, { "isoform_ac": "A0A3Q1N3D4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N3D4/entry", "sequence": { "sequence": "MSATCFMFPVASGLRPPQAGLMPMQQQGFPMVSVMQPNMQGMIGMNYSSQMSQGPIAMQAGIPMGPIPAGGMPYLGQAPFLGMRPPGPQYTPDMQKQFAEEQQKRFEQQQKLLEEERKRRQFEEQKQKLRLLSSVKPKTGEKSRDDALEAIKGNLDGFSRDAKMHPTPASHPKKPDYPTSSHSTKTVSPSPAFLDEEEFSDFMQGPVEVPTCGPSSTSQPFQSFHSTTPLGQLHVQKAGAQPLPPGSSLEEKLLVSCDLSTSGQEQIKFNTSEVGHKALGPGSSKNHPSLMASNGGAVDGRVSGTTTAEAAKTSDQNLCIEESGVGVFPSQDPVQPRMPPWIYNESLVPDAYKKILETTMTPTGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYAVLAMIAATQRGVPAMSPDALNQFPAAPVPTLSGFPVTLPAAVSQPTGMPSGPAGSMPLTLGQPVMGINLVGPVGGAAAQASSGFMSAYAANQVVKPEDDDFQDFQDASKSGSLDDSFSDFQELPASSKSNNSQHGNSAPSLLMPLPGTKASASMDKYAVFKGIAADKPSENTVPFGEPGDKYSAFRELEQTAENKSLGENFAEFRSAGTDDGFTDFKTADSISPLEPPAKDKPFPATFPSGATQQKPQTQVKNPLNLADLDMFSSVTCSNEKPLSFSAAFSVSKPVSTRPQPAGSAAPSAALVSTKTAGLADDFGEFNLFGEYSSPASVGEQDDFADFMAFSNSSVSSEQKADDKYEALKEEASPGPLTSSTGIAGKSGQNSAATSTKYDVFKQLSLEGSGLGGEELKDSTSSGKSDDDFADFHSSKFSSVNSDKSLGEKAVAFRHTKEDSASVKSLDLPSLGGSSVGKEDSEDALSVQFDMKLADVGGELKHVMSDSSLDLPTVSGQHPPAADIEDLKYAAFGTYSSSFAVSTLTSSDWSDRDDASQGRKLSPFVLSAGSGASAAASVLQKKETSFGSSENLTVASLSKVTTFASEDPLPETTFLPFANFKDVIPQASEPKEYESGDFRDFARQDLPVGERSQEAMCLSPASSSASHDTPKECTDDFGEFQSEKPKISKFDFLVANSQGKMKSSEEMIKNELATFDLSVQGSHKRSLSLGDKEISRSSPSPALEQPFRDRSNTLSEKPALPVIRDKYKDLTGEVEENERYAYEWQRCLGSALEVIKKANDTLNGISSSSVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQQLLKDIDKVWNNLIGFMSLATLTPDENSLDFSSCMLRPGIKNAQELACGVCLLNVDSRSRKEEKPAEEHPKKAFNSETDSFKLAYGGHQYHASCANFWINCVEPKPPGLILPDLL", "length": 1364, "header": "tr|A0A3Q1N3D4-1|A0A3Q1N3D4_BOVIN Computationally mapped isoform of Synergin gamma OS=Bos taurus OX=9913 GN=SYNRG PE=4 SV=2 CANONICAL=F1MI41-1" }, "locus": { "chromosome": "19", "start_pos": 13895060, "end_pos": 13812909, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067614.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067614.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063966.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063966.2" } ] } }, { "isoform_ac": "A0AAA9TA43-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TA43/entry", "sequence": { "sequence": "MSATCQPTVHQQMSWISNMCFMFPVASGLRPPQAGLMPMQQQGFPMVSVMQPNMQGMIGMNYSSQMSQGPIAMQAGIPMGPIPAGGMPYLGQAPFLGMRPPGPQYTPDMQKQFAEEQQKRFEQQQKLLEEERKRRQFEEQKQKLRLLSSVKPKTGEKSRDDALEAIKGNLDGFSRDAKMHPTPASHPKKPDYPTSSHSTKTVSPSPAFLDEEEFSDFMQGPVEVPTCGPSSTSQPFQSFHSTTPLGQLHVQKAGAQPLPPGVGVFPSQDPVQPRMPPWIYNESLVPDAYKKILETTMTPTGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYAVLAMIAATQRGVPAMSPDALNQFPAAPVPTLSGFPVTLPAAVSQPTGMPSGPAGSMPLTLGQPVMGINLVGPVGGAAAQASSGFMSAYAANQVVKPEDDDFQDFQDASKSGSLDDSFSDFQELPASSKSNNSQHGNSAPSLLMPLPGTKASASMDKYAVFKGIAADKPSENTVPFGEPGDKYSAFRELEQTAENKSLGENFAEFRSAGTDDGFTDFKTADSISPLEPPAKDKPFPATFPSGATQQKPQTQVKNPLNLADLDMFSSVTCSNEKPLSFSAAFSVSKPVSTRPQPAGSAAPSAALVSTKTAGLADDFGEFNLFGEYSSPASVGEQDDFADFMAFSNSSVSSEQKADDKYEALKEEASPGPLTSSTGIAGKSGQNSAATSTKYDVFKQLSLEGSGLGGEELKDSTSSGKSDDDFADFHSSKFSSVNSDKSLGEKAVAFRHTKEDSASVKSLDLPSLGGSSVGKEDSEDALSVQFDMKLADVGGELKHVMSDSSLDLPTVSGQHPPAADIEDLKYAAFGTYSSSFAVSTLTSSDWSDRDDASQGRKLSPFVLSAGSGASAAASVLQKKETSFGSSENLTVASLSKVTTFASEDPLPETTFLPFANFKDVIPQASEPKEYESGDFRDFARQDLPVGERSQEAMCLSPASSSASHDTPKECTDDFGEFQSEKPKISKFDFLVANSQGKMKSSEEMIKNELATFDLSVQGSHKRSLSLGDKEISRSSPSPALEQPFRDRSNTLSEKPALPVIRDKYKDLTGEVEENERYAYEWQRCLGSALEVIKKANDTLNGISSSSVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQQLLKDIDKVWNNLIGFMSLATLTPDENSLDFSSCMLRPGIKNAQELACGVCLLNVDSRSRAFNSETDSFKLAYGGHQYHASCANFWINCVEPKPPGLILPDLL", "length": 1289, "header": "tr|A0AAA9TA43-1|A0AAA9TA43_BOVIN Computationally mapped isoform of Synergin gamma OS=Bos taurus OX=9913 GN=SYNRG PE=4 SV=1 CANONICAL=F1MI41-1" }, "locus": { "chromosome": "19", "start_pos": 13895060, "end_pos": 13812909, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133730.1", "url": "https://www.ensembl.org/id/ENSBTAT00000133730.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095574.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095574.1" } ] } }, { "isoform_ac": "A0AAA9TQK4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQK4/entry", "sequence": { "sequence": 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"length": 1373, "header": "tr|A0AAA9TQK4-1|A0AAA9TQK4_BOVIN Computationally mapped isoform of Synergin gamma OS=Bos taurus OX=9913 GN=SYNRG PE=4 SV=1 CANONICAL=F1MI41-1" }, "locus": { "chromosome": "19", "start_pos": 13895850, "end_pos": 13812909, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128498.1", "url": "https://www.ensembl.org/id/ENSBTAT00000128498.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100866.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100866.1" } ] } }, { "isoform_ac": "A0AAA9U0I4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0I4/entry", "sequence": { "sequence": "MALRPGSGAGGGGAAGAGTGAAGGGSFMFPVASGLRPPQAGLMPMQQQGFPMVSVMQPNMQGMIGMNYSSQMSQGPIAMQAGIPMGPIPAGGMPYLGQAPFLGMRPPGPQYTPDMQKQFAEEQQKRFEQQQKLLEEERKRRQFEEQKQKLRLLSSVKPKTGEKSRDDALEAIKGNLDGFSRDAKMHPTPASHPKKPDYPTSSHSTKTVSPSPAFLDEEEFSDFMQGPVEVPTCGPSSTSQPFQSFHSTTPLGQLHVQKAGAQPLPPGVGVFPSQDPVQPRMPPWIYNESLVPDAYKKILETTMTPTGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYAVLAMIAATQRGVPAMSPDALNQFPAAPVPTLSGFPVTLPAAVSQPTGMPSGPAGSMPLTLGQPVMGINLVGPVGGAAAQASSGFMSAYAANQVVKPEDDDFQDFQDASKSGSLDDSFSDFQELPASSKSNNSQHGNSAPSLLMPLPGTKASASMDKYAVFKGIAADKPSENTVPFGEPGDKYSAFRELEQTAENKSLGENFAEFRSAGTDDGFTDFKTADSISPLEPPAKDKPFPATFPSGATQQKPQTQVKNPLNLADLDMFSSVTCSNEKPLSFSAAFSVSKPVSTRPQPAGSAAPSAALVSTKTAGLADDFGEFNLFGEYSSPASVGEQDDFADFMAFSNSSVSSEQKADDKYEALKEEASPGPLTSSTGIAGKSGQNSAATSTKYDVFKQLSLEGSGLGGEELKDSTSSGKSDDDFADFHSSKFSSVNSDKSLGEKAVAFRHTKEDSASVKSLDLPSLGGSSVGKEDSEDALSVQFDMKLADVGGELKHVMSDSSLDLPTVSGQHPPAADIEDLKYAAFGTYSSSFAVSTLTSSDWSDRDDASQGRKLSPFVLSAGSGASAAASVLQKKETSFGSSENLTVASLSKVTTFASEDPLPETTFLPFANFKDVIPQASEPKEYESGDFRDFARQDLPVGERSQEAMCLSPASSSASHDTPKECTDDFGEFQSEKPKISKFDFLVANSQGKMKSSEEMIKNELATFDLSVQGSHKRSLSLGDKEISRSSPSPALEQPFRDRSNTLSEKPALPVIRDKYKDLTGEVEENERYAYEWQRCLGSALEVIKKANDTLNGISSSSVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQQLLKDIDKVWNNLIGFMSLATLTPDENSLDFSSCMLRPGIKNAQELACGVCLLNVDSRSRAFNSETDSFKLAYGGHQYHASCANFWINCVEPKPPGLILPDLL", "length": 1295, "header": "tr|A0AAA9U0I4-1|A0AAA9U0I4_BOVIN Computationally mapped isoform of Synergin gamma OS=Bos taurus OX=9913 GN=SYNRG PE=4 SV=1 CANONICAL=F1MI41-1" }, "locus": { "chromosome": "19", "start_pos": 13895850, "end_pos": 13812909, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123000.1", "url": "https://www.ensembl.org/id/ENSBTAT00000123000.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102582.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102582.1" } ] } }, { "isoform_ac": "F1MI41-1", "url": "https://www.uniprot.org/uniprotkb/F1MI41/entry", "sequence": { "sequence": "MALRPGSGAGGGGAAGAGTGAAGGGSFMFPVASGLRPPQAGLMPMQQQGFPMVSVMQPNMQGMIGMNYSSQMSQGPIAMQAGIPMGPIPAGGMPYLGQAPFLGMRPPGPQYTPDMQKQFAEEQQKRFEQQQKLLEEERKRRQFEEQKQKLRLLSSVKPKTGEKSRDDALEAIKGNLDGFSRDAKMHPTPASHPKKPDYPTSSHSTKTVSPSPAFLDEEEFSDFMQGPVEVPTCGPSSTSQPFQSFHSTTPLGQLHVQKAGAQPLPPGSSLEEKLLVSCDLSTSGQEQIKFNTSEVGHKALGPGSSKNHPSLMASNGGAVDGRVSGTTTAEAAKTSDQNLCIEESGVGVFPSQDPVQPRMPPWIYNESLVPDAYKKILETTMTPTGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYAVLAMIAATQRGVPAMSPDALNQFPAAPVPTLSGFPVTLPAAVSQPTGMPSGPAGSMPLTLGQPVMGINLVGPVGGAAAQASSGFMSAYAANQVVKPEDDDFQDFQDASKSGSLDDSFSDFQELPASSKSNNSQHGNSAPSLLMPLPGTKASASMDKYAVFKGIAADKPSENTVPFGEPGDKYSAFRELEQTAENKSLGENFAEFRSAGTDDGFTDFKTADSISPLEPPAKDKPFPATFPSGATQQKPQTQVKNPLNLADLDMFSSVTCSNEKPLSFSAAFSVSKPVSTRPQPAGSAAPSAALVSTKTAGLADDFGEFNLFGEYSSPASVGEQDDFADFMAFSNSSVSSEQKADDKYEALKEEASPGPLTSSTGIAGKSGQNSAATSTKYDVFKQLSLEGSGLGGEELKDSTSSGKSDDDFADFHSSKFSSVNSDKSLGEKAVAFRHTKEDSASVKSLDLPSLGGSSVGKEDSEDALSVQFDMKLADVGGELKHVMSDSSLDLPTVSGQHPPAADIEDLKYAAFGTYSSSFAVSTLTSSDWSDRDDASQGRKLSPFVLSAGSGASAAASVLQKKETSFGSSENLTVASLSKVTTFASEDPLPETTFLPFANFKDVIPQASEPKEYESGDFRDFARQDLPVGERSQEAMCLSPASSSASHDTPKECTDDFGEFQSEKPKISKFDFLVANSQGKMKSSEEMIKNELATFDLSVQGSHKRSLSLGDKEISRSSPSPALEQPFRDRSNTLSEKPALPVIRDKYKDLTGEVEENERYAYEWQRCLGSALEVIKKANDTLNGISSSSVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQQLLKDIDKVWNNLIGFMSLATLTPDENSLDFSSCMLRPGIKNAQELACGVCLLNVDSRSRKEEKPAEEHPKKAFNSETDSFKLAYGGHQYHASCANFWINCVEPKPPGLILPDLL", "length": 1385, "header": "tr|F1MI41-1|F1MI41_BOVIN Isoform 1 of Synergin gamma OS=Bos taurus OX=9913 GN=SYNRG PE=4 SV=2 CANONICAL=F1MI41-1" }, "locus": { "chromosome": "19", "start_pos": 13895850, "end_pos": 13812909, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000013601.6", "url": "https://www.ensembl.org/id/ENSBTAT00000013601.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000013601.5", "url": "https://www.ensembl.org/id/ENSBTAP00000013601.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "clathrin coat of trans-Golgi network vesicle", "id": "GO:0030130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030130", "evidence": [ { "database": "UniProtKB", "id": "F1MI41", "url": "https://www.uniprot.org/uniprotkb/F1MI41" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1009, "end_pos": 1011, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1217, "end_pos": 1219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 365, "end_pos": 367, "annotation": "n_glycosylation_sequon" }, { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 557, "end_pos": 559, "annotation": "n_glycosylation_sequon" }, { "start_pos": 621, "end_pos": 623, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" }, { "start_pos": 770, "end_pos": 772, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1MI41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI41" }, { "id": "PS50031", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50031" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EH", "eco_id": "ECO_0000259", "start_pos": 365, "end_pos": 476, "start_aa": "Asn", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1009, "end_pos": 1011 }, { "start_pos": 1217, "end_pos": 1219 }, { "start_pos": 291, "end_pos": 293 }, { "start_pos": 365, "end_pos": 367 }, { "start_pos": 413, "end_pos": 415 }, { "start_pos": 557, "end_pos": 559 }, { "start_pos": 621, "end_pos": 623 }, { "start_pos": 67, "end_pos": 69 }, { "start_pos": 770, "end_pos": 772 } ] }, 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BPK9-1", "uniprot_ac": "E1BPK9", "uniprot_id": "E1BPK9_BOVIN", "mass": { "chemical_mass": 138176.0, "monoisotopic_mass": 138176.0 }, "refseq": { "ac": "XP_024841016", "name": "autism susceptibility gene 2 protein isoform X8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024841016" }, "gene_names": [ { "name": "AUTS2", "type": "recommended", "evidence": [ { "id": "E1BPK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPK9" } ] }, { "name": "AUTS2", "type": "synonym", "evidence": [ { "id": "XP_024841016", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024841016" } ] } ], "protein_names": [ { "name": "Activator of transcription and developmental regulator AUTS2", "type": "synonym", "evidence": [ { "id": "E1BPK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPK9/entry#names_and_taxonomy" } ] }, { "name": "autism susceptibility gene 2 protein isoform X8", "type": "synonym", "evidence": [ { "id": "XP_024841016", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024841016" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BPK9", "url": "https://www.uniprot.org/uniprotkb/E1BPK9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "AUTS2", "url": "https://www.uniprot.org/uniprotkb/E1BPK9", "locus": { "chromosome": "25", "start_pos": 29783195, "end_pos": 30996953, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002083", "url": "https://www.ensembl.org/id/ENSBTAG00000002083" } ] } } ], "crossref": [ { "id": "E1BPK9", "url": "https://alphafold.ebi.ac.uk/entry/E1BPK9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002083", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002083", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "615936", "url": "https://www.ncbi.nlm.nih.gov/gene/615936", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR023246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:615936", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:615936", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR14429", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14429", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14429:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14429:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15336", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15336", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8939243", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8939243", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024841016", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024841016", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LQL9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LQL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQL9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MDX4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MDX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SD94", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SD94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SD94-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SD94-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BPK9", "url": "https://www.uniprot.org/uniprotkb/E1BPK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BPK9-1", "url": "https://www.uniprot.org/uniprotkb/E1BPK9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRAPSLASSSGSDKEDNGKPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTPLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKGLRQLKPGQNSCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLFNTVIVNKDPELGVGALPHHDGHDAGPIVPKVSGLERSQEKSQDCGKEPLFEPVVLKDARPQVPPPPPQPQAEPPPRAPSPDPASGPRAEPPPPPPRPGAQPPPAPPEAQPQPAPPQAPRPPRPQSPGPLPPQVLPPAQAHPSAQSLPQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVPGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHALPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKTSNPIDVATRPGTVPHTLLQKDPRLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHSNFLTPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSVFGHKDGPSVQSFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPAPVLPVSTLGHGRSSSEQIRGHLSTEAREKDKCKDREREHSESRKDLGTDEHKAKEGPLAEKDGHGHEGRTAGEEAKQLARVPSPYARAPAADSARPGSAASRDAEPRKGEPAYENPKKSAEVKVKEERKEDHDLPPEAPPTHRSSEPPPPPPPPSSSAGVHPGPLASMPVAVGMPGIHPMNSISGLDRTRMMTPFMGLSPIPGGERFPYPSFHWDPIRDPLRDPYRELDIHRRDPLGRDFLLRNDPLHRLSTPRLYEADRSFRDREPHDYNHHHHHHHHHPLAVDPRREHERGAHLDERERLHVLREDYEHPRLHPVHPASLDGHLPHPGLLTPGLPSMHYPRISPTAGHQNGLLNKTPPTAALSAPPPLISTLGGRPVSPRRTTPLSAEIRERPPSHTLKDIEAR", "length": 1263, "header": "tr|E1BPK9-1|E1BPK9_BOVIN Isoform 1 of Activator of transcription and developmental regulator AUTS2 OS=Bos taurus OX=9913 GN=AUTS2 PE=4 SV=4 CANONICAL=E1BPK9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LQL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQL9/entry", "sequence": { "sequence": "MDGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRAPSLASSSGSDKEDNGKPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTPLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKGLRQLKPGQNSCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLFNTVIVNKDPELGVGALPHHDGHDAGPIVPKVSGLERSQEKSQDCGKEPLFEPVVLKDARPQVPPPPPQPQAEPPPRAPSPDPASGPRAEPPPPPPRPGAQPPPAPPEAQPQPAPPQAPRPPRPQSPGPLPPQVLPPAQAHPSAQSLPQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVPGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHALPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHSNFLTPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSVFGHKDGPSVQSFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPAPVLPVSTLGHGRSSSEQIRGHLSTEAREKDKCKDREREHSESRKDLGTDEHKAKEGPLAEKDGHGHEGRTAGEEAKQLARVPSPYARAPAADSARPGSAASRDAEPRKGEPAYENPKKSAEVKVKEERKEDHDLPPEAPPTHRSSEPPPPPPPPSSSAGVHPGPLASMPVAVGMPGIHPMNSISGLDRTRMMTPFMGLSPIPGGERFPYPSFHWDPIRDPLRDPYRELDIHRRDPLGRDFLLRNDPLHRLSTPRLYEADRSFRDREPHDYNHHHHHHHHHPLAVDPRREHERGAHLDERERLHVLREDYEHPRLHPVHPASLDGHLPHPGLLTPGLPSMHYPRISPTAGHQNGLLNKTPPTAALSAPPPLISTLGGRPVSPRRTTPLSAEIRERPPSHTLKDIEAR", "length": 1239, "header": "tr|A0A3Q1LQL9-1|E1BPK9_BOVIN Computationally mapped isoform of Activator of transcription and developmental regulator AUTS2 OS=Bos taurus OX=9913 GN=AUTS2 PE=4 SV=2 CANONICAL=E1BPK9-1" }, "locus": { "chromosome": "25", "start_pos": 30996754, "end_pos": 29784199, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083495.2", "url": "https://www.ensembl.org/id/ENSBTAT00000083495.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057276.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057276.2" } ] } }, { "isoform_ac": "A0A3Q1MDX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDX4/entry", "sequence": { "sequence": "MFAPPTALPPPPPLTSGSLQVPGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHALPPTAIMPTPAPPMLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKTSNPIDVATRPGTVPHTLLQKDPRLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHSNFLTPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSVFGHKDGPSVQSFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPAPVLPVSTLGHGRSSSEQIRGHLSTEAREKDKCKDREREHSESRKDLGTDEHKAKEGPLAEKDGHGHEGRTAGEEAKQLARVPSPYARAPAADSARPGSAASRDAEPRKGEPAYENPKKSAEVKVKEERKEDHDLPPEAPPTHRSSEPPPPPPPPSSSAGVHPGPLASMPVAVGMPGIHPMNSISGLDRTRMMTPFMGLSPIPGGERFPYPSFHWDPIRDPLRDPYRELDIHRRDPLGRDFLLRNDPLHRLSTPRLYEADRSFRDREPHDYNHHHHHHHHHPLAVDPRREHERGAHLDERERLHVLREDYEHPRLHPVHPASLDGHLPHPGLLTPGLPSMHYPRISPTAGHQNGLLNKTPPTAALSAPPPLISTLGGRPVSPRRTTPLSAEIRERPPSHTLKDIEAR", "length": 791, "header": "tr|A0A3Q1MDX4-1|A0A3Q1MDX4_BOVIN Computationally mapped isoform of Activator of transcription and developmental regulator AUTS2 OS=Bos taurus OX=9913 GN=AUTS2 PE=4 SV=1 CANONICAL=E1BPK9-1" }, "locus": { "chromosome": "25", "start_pos": 29812883, "end_pos": 29784199, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067784.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067784.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069166.1", "url": "https://www.ensembl.org/id/ENSBTAP00000069166.1" } ] } }, { "isoform_ac": "A0AAA9SD94-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SD94/entry", "sequence": { "sequence": "MDGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRAPSLASSSGSDKEDNGKPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTPLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKGLRQLKPGQNSCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLFNTVIVNKDPELGVGALPHHDGHDAGPIVPKVSGLERSQEKSQDCGKEPLFEPVVLKDARPQVPPPPPQPQAEPPPRAPSPDPASGPRAEPPPPPPRPGAQPPPAPPEAQPQPAPPQAPRPPRPQSPGPLPPQVLPPAQAHPSAQSLPQPLSAYNSSSLSLNSLRRRSRQTWRAQVTSLFVSIGVAPVGRVAGTGSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVPGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHALPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKTSNPIDVATRPGTVPHTLLQKDPRLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHSNFLTPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSVFGHKDGPSVQSFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPAPVLPVSTLGHGRSSSEQIRGHLSTEAREKDKCKDREREHSESRKDLGTDEHKAKEGPLAEKDGHGHEGRTAGEEAKQLARVPSPYARAPAADSARPGSAASRDAEPRKGEPAYENPKKSAEVKVKEERKEDHDLPPEAPPTHRSSEPPPPPPPPSSSAGVHPGPLASMPVAVGMPGIHPMNSISGLDRTRMMTPFMGLSPIPGGERFPYPSFHWDPIRDPLRDPYRELDIHRRDPLGRDFLLRNDPLHRLSTPRLYEADRSFRDREPHDYNHHHHHHHHHPLAVDPRREHERGAHLDERERLHVLREDYEHPRLHPVHPASLDGHLPHPGLLTPGLPSMHYPRISPTAGHQNGLLNKTPPTAALSAPPPLISTLGGRPVSPRRTTPLSAEIRERPPSHTLKDIEAR", "length": 1293, "header": "tr|A0AAA9SD94-1|A0AAA9SD94_BOVIN Computationally mapped isoform of Activator of transcription and developmental regulator AUTS2 OS=Bos taurus OX=9913 GN=AUTS2 PE=4 SV=1 CANONICAL=E1BPK9-1" }, "locus": { "chromosome": "25", "start_pos": 30996754, "end_pos": 29784199, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000117208.1", "url": "https://www.ensembl.org/id/ENSBTAT00000117208.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080295.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080295.1" } ] } }, { "isoform_ac": "E1BPK9-1", "url": "https://www.uniprot.org/uniprotkb/E1BPK9/entry", "sequence": { "sequence": "MDGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRAPSLASSSGSDKEDNGKPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTPLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKGLRQLKPGQNSCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLFNTVIVNKDPELGVGALPHHDGHDAGPIVPKVSGLERSQEKSQDCGKEPLFEPVVLKDARPQVPPPPPQPQAEPPPRAPSPDPASGPRAEPPPPPPRPGAQPPPAPPEAQPQPAPPQAPRPPRPQSPGPLPPQVLPPAQAHPSAQSLPQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVPGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHALPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKTSNPIDVATRPGTVPHTLLQKDPRLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHSNFLTPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSVFGHKDGPSVQSFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPAPVLPVSTLGHGRSSSEQIRGHLSTEAREKDKCKDREREHSESRKDLGTDEHKAKEGPLAEKDGHGHEGRTAGEEAKQLARVPSPYARAPAADSARPGSAASRDAEPRKGEPAYENPKKSAEVKVKEERKEDHDLPPEAPPTHRSSEPPPPPPPPSSSAGVHPGPLASMPVAVGMPGIHPMNSISGLDRTRMMTPFMGLSPIPGGERFPYPSFHWDPIRDPLRDPYRELDIHRRDPLGRDFLLRNDPLHRLSTPRLYEADRSFRDREPHDYNHHHHHHHHHPLAVDPRREHERGAHLDERERLHVLREDYEHPRLHPVHPASLDGHLPHPGLLTPGLPSMHYPRISPTAGHQNGLLNKTPPTAALSAPPPLISTLGGRPVSPRRTTPLSAEIRERPPSHTLKDIEAR", "length": 1263, "header": "tr|E1BPK9-1|E1BPK9_BOVIN Isoform 1 of Activator of transcription and developmental regulator AUTS2 OS=Bos taurus OX=9913 GN=AUTS2 PE=4 SV=4 CANONICAL=E1BPK9-1" }, "locus": { "chromosome": "25", "start_pos": 30996754, "end_pos": 29784199, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002697.7", "url": "https://www.ensembl.org/id/ENSBTAT00000002697.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002697.7", "url": "https://www.ensembl.org/id/ENSBTAP00000002697.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1204, "start_aa": "Thr", "end_pos": 1204, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1204", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 557, "start_aa": "Thr", "end_pos": 557, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr557", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 804, "start_aa": "Thr", "end_pos": 804, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr804", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:615936", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:615936", "resource": "KEGG Pathway" }, { "id": "R-BTA-8939243", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8939243", "resource": "Reactome", "description": "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "E1BPK9", "url": "https://www.uniprot.org/uniprotkb/E1BPK9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BPK9", "url": "https://www.uniprot.org/uniprotkb/E1BPK9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1213, "end_pos": 1215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 436, "end_pos": 438, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 557, 804, 1204 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1213, "end_pos": 1215 }, { "start_pos": 394, "end_pos": 396 }, { "start_pos": 436, "end_pos": 438 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"uniprot_ac": "F1MIE5", "uniprot_id": "F1MIE5_BOVIN", "mass": { "chemical_mass": 37403.0, "monoisotopic_mass": 37403.0 }, "refseq": { "ac": "NP_001178287", "name": "SLAM family member 7 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178287" }, "gene_names": [ { "name": "SLAMF7", "type": "recommended", "evidence": [ { "id": "F1MIE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIE5" } ] }, { "name": "SLAMF7", "type": "synonym", "evidence": [ { "id": "NP_001178287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178287" } ] } ], "protein_names": [ { "name": "SLAM family member 7 precursor", "type": "synonym", "evidence": [ { "id": "NP_001178287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178287" } ] }, { "name": "SLAM family member 7", "type": "synonym", "evidence": [ { "id": "F1MIE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIE5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "The SLAMF-AS2 isoforms are expressed the lowest levels among the three transcripts in both normal and infected mammary tissues.", "evidence": [ { "database": "RefSeq", "id": "NP_001178287", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178287" }, { "database": "PubMed", "id": "21769477", "url": "https://glygen.org/publication/PubMed/21769477" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1MIE5", "url": "https://www.uniprot.org/uniprotkb/F1MIE5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SLAMF7", "url": "https://www.uniprot.org/uniprotkb/F1MIE5", "locus": { "chromosome": "3", "start_pos": 8848948, "end_pos": 8864962, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001197", "url": "https://www.ensembl.org/id/ENSBTAG00000001197" } ] } } ], "crossref": [ { "id": "F1MIE5", "url": "https://alphafold.ebi.ac.uk/entry/F1MIE5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001197", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001197", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "790164", "url": "https://www.ncbi.nlm.nih.gov/gene/790164", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015631", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015631", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:790164", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:790164", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DSIVWIF", "url": "https://omabrowser.org/oma/group/DSIVWIF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1MIE5", "url": "https://www.orthodb.org/?gene=F1MIE5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12080", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12080", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12080:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12080:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-198933", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-198933", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001178287", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178287", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LRJ7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LRJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SN84", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SN84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SN84-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SN84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZQ6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MIE5", "url": "https://www.uniprot.org/uniprotkb/F1MIE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MIE5-1", "url": "https://www.uniprot.org/uniprotkb/F1MIE5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGAPACFIFLLCQLTGPAASGIPKKLVGAIGGSVIFPLNLSVNLVDSIIWVFNSTTLVTIQPKTAGKKALVIVTQKRNLERVNFPHEGYSLKLSRLKKNDSGIYRVEIHSSTLQDPLTQEYELHVYEYLSKPKVVIGLQENKNGTCVTNLTCSMEHGEEDVTYSWKSLDQTTNESHRGSILPISWRWEKSDMTFICMASNPISSNSSNPIFAQNLCEGAAGGQAPYVVLYVLLSFFLLCSLALVLIIFIIQRERKKEIIEEKKELDTHQKTLPFPPIPEEMPEYDTISTFNGTIPEENPANTIYSTVHIAPKVTEPYSLPMLSDTPTASIYNNVM", "length": 336, "header": "tr|F1MIE5-1|F1MIE5_BOVIN Isoform 1 of SLAM family member 7 OS=Bos taurus OX=9913 GN=SLAMF7 PE=4 SV=2 CANONICAL=F1MIE5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LRJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRJ7/entry", "sequence": { "sequence": "MLGAPACFIFLLCQLTGPAASGIPKKLVGAIGGSVIFPLNLSVNLVDSIIWVFNSTTLVTIQPKTAGKKALVIVTQKRNLERVNFPHEGYSLKLSRLKKNDSGIYRVEIHSSTLQDPLTQEYELHVYEYLSKPKVVIGLQENKNGTCVTNLTCSMEHGEEDVTYSWKSLDQTTNESHRGSILPISWRWEKSDMTFICMASNPISSNSSNPIFAQNLCEGAAGGQAPYVVLYVLLSFFLLCSLALVLIIFIIQRERKKGHYSRGKPSQYHLFHCAHSPKGNRTLLPAHVVRYTNGIYL", "length": 297, "header": "tr|A0A3Q1LRJ7-1|F1MIE5_BOVIN Computationally mapped isoform of SLAM family member 7 OS=Bos taurus OX=9913 GN=SLAMF7 PE=4 SV=1 CANONICAL=F1MIE5-1" }, "locus": { "chromosome": "3", "start_pos": 8864930, "end_pos": 8849903, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079658.2", "url": "https://www.ensembl.org/id/ENSBTAT00000079658.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059774.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059774.2" } ] } }, { "isoform_ac": "A0AAA9SN84-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SN84/entry", "sequence": { "sequence": "MLGAPACFIFLLCQLTEYLSKPKVVIGLQENKNGTCVTNLTCSMEHGEEDVTYSWKSLDQTTNESHRGSILPISWRWEKSDMTFICMASNPISSNSSNPIFAQNLCEGHYSRGKPSQYHLFHCAHSPKGNRTLLPAHVVRYTNGIYL", "length": 147, "header": "tr|A0AAA9SN84-1|A0AAA9SN84_BOVIN Computationally mapped isoform of SLAM family member 7 OS=Bos taurus OX=9913 GN=SLAMF7 PE=4 SV=1 CANONICAL=F1MIE5-1" }, "locus": { "chromosome": "3", "start_pos": 8864930, "end_pos": 8849903, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105733.1", "url": "https://www.ensembl.org/id/ENSBTAT00000105733.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085429.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085429.1" } ] } }, { "isoform_ac": "A0AAA9SZQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZQ6/entry", "sequence": { "sequence": "MLGAPACFIFLLCQLTEYLSKPKVVIGLQENKNGTCVTNLTCSMEHGEEDVTYSWKSLDQTTNESHRGSILPISWRWEKSDMTFICMASNPISSNSSNPIFAQNLCEEIIEEKKELDTHQKTLPFPPIPEEMPEYDTISTFNGTIPEENPANTIYSTVHIAPKVTEPYSLPMLSDTPTASIYNNVM", "length": 186, "header": "tr|A0AAA9SZQ6-1|A0AAA9SZQ6_BOVIN Computationally mapped isoform of SLAM family member 7 OS=Bos taurus OX=9913 GN=SLAMF7 PE=4 SV=1 CANONICAL=F1MIE5-1" }, "locus": { "chromosome": "3", "start_pos": 8864930, "end_pos": 8849890, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119015.1", "url": "https://www.ensembl.org/id/ENSBTAT00000119015.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091956.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091956.1" } ] } }, { "isoform_ac": "F1MIE5-1", "url": "https://www.uniprot.org/uniprotkb/F1MIE5/entry", "sequence": { "sequence": "MLGAPACFIFLLCQLTGPAASGIPKKLVGAIGGSVIFPLNLSVNLVDSIIWVFNSTTLVTIQPKTAGKKALVIVTQKRNLERVNFPHEGYSLKLSRLKKNDSGIYRVEIHSSTLQDPLTQEYELHVYEYLSKPKVVIGLQENKNGTCVTNLTCSMEHGEEDVTYSWKSLDQTTNESHRGSILPISWRWEKSDMTFICMASNPISSNSSNPIFAQNLCEGAAGGQAPYVVLYVLLSFFLLCSLALVLIIFIIQRERKKEIIEEKKELDTHQKTLPFPPIPEEMPEYDTISTFNGTIPEENPANTIYSTVHIAPKVTEPYSLPMLSDTPTASIYNNVM", "length": 336, "header": "tr|F1MIE5-1|F1MIE5_BOVIN Isoform 1 of SLAM family member 7 OS=Bos taurus OX=9913 GN=SLAMF7 PE=4 SV=2 CANONICAL=F1MIE5-1" }, "locus": { "chromosome": "3", "start_pos": 8864930, "end_pos": 8849890, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001585.6", "url": "https://www.ensembl.org/id/ENSBTAT00000001585.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001585.5", "url": "https://www.ensembl.org/id/ENSBTAP00000001585.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Alternative splicing and mRNA expression analysis of bovine SLAMF7 gene in healthy and mastitis mammary tissues.", "journal": "Molecular biology reports", "date": "2012-04", "authors": "Ju Zhihua, Wang Changfa, Li Qiuling, Hou Minghai, Gao Shuai, Hou Qinlei, Li Jianbin, Huang Jinming, Zhong Jifeng", "evidence": [ { "database": "RefSeq", "id": "NP_001178287", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178287" } ], "reference": [ { "type": "PubMed", "id": "21769477", "url": "https://glygen.org/publication/PubMed/21769477" } ] } ], "pathway": [ { "id": "bta:790164", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:790164", "resource": "KEGG Pathway" }, { "id": "R-BTA-198933", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-198933", "resource": "Reactome", "description": "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061I653-1", "protein_name": "SLAM family member 7", "gene_name": "Slamf7", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGFSTFIIFTSVLCQLPVTATSGPLKEVVGALGGSVTFTVSFPEKQIDTVIWTFNTFTVAIVNKDNAKVLQNPKKEKILFPDGSYSMKLSQLKKNDSGVYRAEIHSTSLQSPFTQEYVLYVYETLSAPKVTTDEQPSKNGSCTTKLTCSVEEEGDNVTYSWKAIGQGAHELHDGAILPISWKLGEKEKTLICMARNPISHSSSNPVLARNLCEDTANLDKSSPRFILYTLPVAIVFSLTLIIAFAVRTEKGKGSKKDTERVDNFCPLEENTEYATIPYINERSLEDDAANTLYSTVQIPKAVKSPSYLPAEPPMWRQLSFENII", "length": 325 }, "evidence": [ { "id": "F1MIE5", "url": "https://omabrowser.org/oma/group/F1MIE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A0G2K5F6-1", "protein_name": "SLAM family member 7", "gene_name": "Slamf7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARFSTHIIFTSVLCQLTVTAASGTPKEVAGALDGSVTFTLNTTEVKVDSVVWTFKTLFLAIINKNGTIKSQSYEERIVFLDRHSMKLSQLKKNDSGDYRAEIHIASNSLSSPFMQEYVLHVHEHLSRPKVNTDSQSSKDGTCILNLTCSVERGGENVTYSWKAVGQTVDEFHDSANLSISWRLGEKDKTIICTARNPVSSSSSTPLLAQKLCKDAAKDLNSPRVLKYILCVTLVLVLFCILLVTILFRWIPKGKGFEEDKKRVDGHQEMSNSCPHLENTDYDTIPYTEKTRPEEDAPNTLYSTVQIPKVVKSPSSPPAMPHPPRSLSFENVI", "length": 333 }, "evidence": [ { "id": "F1MIE5", "url": "https://omabrowser.org/oma/group/F1MIE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BHK6-1", "protein_name": "SLAM family member 7", "gene_name": "Slamf7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARFSTYIIFTSVLCQLTVTAASGTLKKVAGALDGSVTFTLNITEIKVDYVVWTFNTFFLAMVKKDGVTSQSSNKERIVFPDGLYSMKLSQLKKNDSGAYRAEIYSTSSQASLIQEYVLHVYKHLSRPKVTIDRQSNKNGTCVINLTCSTDQDGENVTYSWKAVGQGDNQFHDGATLSIAWRSGEKDQALTCMARNPVSNSFSTPVFPQKLCEDAATDLTSLRGILYILCFSAVLILFAVLLTIFHTTWIKKGKGCEEDKKRVDRHQEMPDLCPHLEENADYDTIPYTEKRRPEEDAPNTFYSTVQIPKVVKSPSSLPAKPLVPRSLSFENVI", "length": 333 }, "evidence": [ { "id": "F1MIE5", "url": "https://omabrowser.org/oma/group/F1MIE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NQ25-1", "protein_name": "SLAM family member 7", "gene_name": "SLAMF7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGSPTCLTLIYILWQLTGSAASGPVKELVGSVGGAVTFPLKSKVKQVDSIVWTFNTTPLVTIQPEGGTIIVTQNRNRERVDFPDGGYSLKLSKLKKNDSGIYYVGIYSSSLQQPSTQEYVLHVYEHLSKPKVTMGLQSNKNGTCVTNLTCCMEHGEEDVIYTWKALGQAANESHNGSILPISWRWGESDMTFICVARNPVSRNFSSPILARKLCEGAADDPDSSMVLLCLLLVPLLLSLFVLGLFLWFLKRERQEEYIEEKKRVDICRETPNICPHSGENTEYDTIPHTNRTILKEDPANTVYSTVEIPKKMENPHSLLTMPDTPRLFAYENVI", "length": 335 }, "evidence": [ { "id": "F1MIE5", "url": "https://omabrowser.org/oma/group/F1MIE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1MIE5", "url": "https://www.uniprot.org/uniprotkb/F1MIE5" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "F1MIE5", "url": "https://www.uniprot.org/uniprotkb/F1MIE5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "F1MIE5", "url": "https://www.uniprot.org/uniprotkb/F1MIE5" } ], "pmid": "" }, { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "F1MIE5", "url": "https://www.uniprot.org/uniprotkb/F1MIE5" } ], "pmid": "" }, { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "F1MIE5", "url": "https://www.uniprot.org/uniprotkb/F1MIE5" } ], "pmid": "" }, { "name": "T cell activation", "id": "GO:0042110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042110", "evidence": [ { "database": "UniProtKB", "id": "F1MIE5", "url": "https://www.uniprot.org/uniprotkb/F1MIE5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1MIE5", "url": "https://www.uniprot.org/uniprotkb/F1MIE5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 292, "end_pos": 294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1MIE5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 336, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1MIE5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1MIE5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1MIE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIE5" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 133, "end_pos": 213, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], 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"E1BM57-1", "url": "https://www.uniprot.org/uniprotkb/E1BM57/entry", "sequence": { "sequence": "MTRFWVCIAGAGFFLALLVLHSRFCASRLPPHLHLAFKISWRAEEILYRLDVDWPKYSEYFTGATFCVAVDSLNGLVYVGQRGDNIPKVLVFTEDGYFLRSWNYTVDTPHGIFAASTPQEKSVWITDVGSGFYGHTIKKYNSFGDLVQVLGTPGKKGTGLNPLQFDNPAELHVDDTGDIYIVDGDGGLNNRLIKLSQDFMILWLRGENGTGPAKFNIPHSVTVDSTGRVWVADRGNKRLQVFDKDTGDWLGEWKNCFSEEGPSAVRFTPDGKYVVVAQLNLSRLLILAAPPVGNIGDCFVVSTIQLADQVSPHLLEVSRETGAVYVAEIGAKQVQKYIPVNSKLLERWDLD", "length": 351, "header": "tr|E1BM57-1|E1BM57_BOVIN Isoform 1 of NHL repeat-containing protein 3 OS=Bos taurus OX=9913 GN=NHLRC3 PE=4 SV=2 CANONICAL=E1BM57-1" }, "locus": { "chromosome": "12", "start_pos": 23218941, "end_pos": 23211329, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014541.6", "url": "https://www.ensembl.org/id/ENSBTAT00000014541.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014541.5", "url": "https://www.ensembl.org/id/ENSBTAP00000014541.5" } ] } } ], "glycosylation": [], 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"expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1MB66", "url": "https://www.uniprot.org/uniprotkb/F1MB66" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "C11H2orf78", "url": "https://www.uniprot.org/uniprotkb/F1MB66", "locus": { "chromosome": "11", "start_pos": 10833575, "end_pos": 10837538, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000039878", "url": "https://www.ensembl.org/id/ENSBTAG00000039878" } ] } } ], "crossref": [ { "id": "F1MB66", "url": "https://alphafold.ebi.ac.uk/entry/F1MB66", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000039878", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000039878", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR027898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040292", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040292", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QDFCFQP", "url": "https://omabrowser.org/oma/group/QDFCFQP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1MB66", "url": "https://www.orthodb.org/?gene=F1MB66", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31466", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31466", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31466:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31466:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15442", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15442", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1MB66", "url": "https://www.uniprot.org/uniprotkb/F1MB66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MB66-1", "url": "https://www.uniprot.org/uniprotkb/F1MB66-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "LTENFQNPSALGTQNSLQLSLPAVSNAASLTESVCTFSRVSAPALSSAWLLPAGSDTSFQPLMSSAYLYQHSSTTMLSGVTGQSQLSTSAASYPGVFEWNITGSTERKSSSLGDFTVTVIDQDTAVSSMSMAAQYDKTSDINSKVPLYPSLSASLVQGTPSQIPNQGHSLSLPHQGGSQVYYYHQGTLGPLLSEELGPRLQSYGSVSYAGSRTSAQPEMVMVLKEIQPTNILPPASTSGVYYSVSAQPITDTGFQGEMENSLGLQPPSQTFCLSETSEFPRSCISRNIQILESNPPLELGDVSRIAPVQSASNLLALPPAPSQEQTENKNLDDMKTKFSKPLDDLLASIDPLSQEEQLVSENVNLGKNSLSFEDLGTLENGFESSSGFADIATLVEDIHLPQFFHSLKDLDQVQEKPNVIKAPSDQPRKNKHKASESVSDAPKAKIQPKDPECPFGGEVIICNAAVSDKAPVNTAKQPNSKTQNTATSRTNKTKSHGQEKTKRTRENKKAEENKPSGNKVKAEEKPSVPKMKRKKNQPDFSQENFKKPRSCLGMHMLESVQVFHALGKKSDQKTGLNSSRVLGNSSNPKDPQPSPAIKSWLNTPCEGKGPEKTPVKAQKPDDSAEKECLSPSQYELPPPGKVKLVPLPFPTLDKPQARPVPRRPQSLASYRPAVAYPAWPGSTNSAQPAAVNASRPAPASLPGPAKPAQTTVTNPTRPGLTKPTQPSVPQSAAPRPVPYRTSSCTSLQRESVPPAVTKHQSPPKPQTQFLLQDFCFQPIPWRKPNVPEPVMSKPITKEQRPEREAMKRKAQLERENAAKYTSLGKVQYFIEREKEMEIARYYGYAM", "length": 846, "header": "tr|F1MB66-1|F1MB66_BOVIN Isoform 1 of Chromosome 11 C2orf78 homolog OS=Bos taurus OX=9913 GN=C11H2orf78 PE=4 SV=3 CANONICAL=F1MB66-1" }, "isoforms": [ { "isoform_ac": "F1MB66-1", "url": "https://www.uniprot.org/uniprotkb/F1MB66/entry", "sequence": { "sequence": "LTENFQNPSALGTQNSLQLSLPAVSNAASLTESVCTFSRVSAPALSSAWLLPAGSDTSFQPLMSSAYLYQHSSTTMLSGVTGQSQLSTSAASYPGVFEWNITGSTERKSSSLGDFTVTVIDQDTAVSSMSMAAQYDKTSDINSKVPLYPSLSASLVQGTPSQIPNQGHSLSLPHQGGSQVYYYHQGTLGPLLSEELGPRLQSYGSVSYAGSRTSAQPEMVMVLKEIQPTNILPPASTSGVYYSVSAQPITDTGFQGEMENSLGLQPPSQTFCLSETSEFPRSCISRNIQILESNPPLELGDVSRIAPVQSASNLLALPPAPSQEQTENKNLDDMKTKFSKPLDDLLASIDPLSQEEQLVSENVNLGKNSLSFEDLGTLENGFESSSGFADIATLVEDIHLPQFFHSLKDLDQVQEKPNVIKAPSDQPRKNKHKASESVSDAPKAKIQPKDPECPFGGEVIICNAAVSDKAPVNTAKQPNSKTQNTATSRTNKTKSHGQEKTKRTRENKKAEENKPSGNKVKAEEKPSVPKMKRKKNQPDFSQENFKKPRSCLGMHMLESVQVFHALGKKSDQKTGLNSSRVLGNSSNPKDPQPSPAIKSWLNTPCEGKGPEKTPVKAQKPDDSAEKECLSPSQYELPPPGKVKLVPLPFPTLDKPQARPVPRRPQSLASYRPAVAYPAWPGSTNSAQPAAVNASRPAPASLPGPAKPAQTTVTNPTRPGLTKPTQPSVPQSAAPRPVPYRTSSCTSLQRESVPPAVTKHQSPPKPQTQFLLQDFCFQPIPWRKPNVPEPVMSKPITKEQRPEREAMKRKAQLERENAAKYTSLGKVQYFIEREKEMEIARYYGYAM", "length": 846, "header": "tr|F1MB66-1|F1MB66_BOVIN Isoform 1 of Chromosome 11 C2orf78 homolog OS=Bos taurus OX=9913 GN=C11H2orf78 PE=4 SV=3 CANONICAL=F1MB66-1" }, "locus": { "chromosome": "11", "start_pos": 10837538, "end_pos": 10833578, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000054996.3", "url": "https://www.ensembl.org/id/ENSBTAT00000054996.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000051973.3", "url": "https://www.ensembl.org/id/ENSBTAP00000051973.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A6NCI8-1", "protein_name": "Uncharacterized protein C2orf78", "gene_name": "C2orf78", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHWLASATQTSASIVSSSLLSAVDVSSSLTMSEYFQNTSLPGTANSRQFSLPVVSNAAFLTGSISNFSRASAPAISSAWLQPSASGTSFQPLMGSAYLYQHSSTTMLSGVTGQSHICTSAASYPGVFEWDSTASTVKKSSSLRDFTVTVIDQNTAVSSMSMTAQYYKTSDTNTMVPLYPSLSASLVQGTLTQIPNQQGHNLSLPCQIGSQVYYYNQGTLGPQLSCLQSYGSVSYTGYRASAHQPEMVMVLKEVQPTNVLPPVSTSGMYYSVSSQPITETSVQVMETSLGMDTSLGLQSPSQTFCLPQTPEFSKSFSSRNTQTLESNPSPELGDISITPVQSPTNLLTLSPAPSQEKNENENLDEIKTNLSKPLDVHQILIGNQDPPLLPVEIPDIHPLLACIDPLGQEEQPGSENANLRNKSLSLEDQGIFENGIESSSDLADITTWVEDTYLPPIFSSLQDLDQPESPSAKKAKDTSAIKVNQVQEKSCVIKGHSDQVRKNKHKASEPIQGAPKAKIQPKNPECLLEREVVVGSATVSNSASVNKAKHSSNKPHKAASSRISKTKSHGQEKTKGNRKNSSKKSEESKQSGKKVKVEEKQTIPNMKRKKNQPELSQKTLKKPRSSLGMHMLESVQVFHALGKKIDMKTGFSSSRTLGSSSNTQNRQPFPALKPWLDIQHEGKGPEKIQVKAQKLDGSAEKECTSPSHSELPPPGKVKLIPLPFLTLDQPQARHVSRRPNPLASRRPAVAYPARPDSTNSAQSNAVNPSRPAPTNTSLTGPATPAQPISAKATQPSSANPTQPTVPQSAASRPSAYKTSSCSSLQREPVSTAVTSLRSLPKPQNQFLIQDFSLQPRPWRKPTVPEPVMSTPITEEQRPEREAMKRKAQQERENAAKYTSLGKVQFFIERERDMEIAEYYGYTI", "length": 922 }, "evidence": [ { "id": "F1MB66", "url": "https://omabrowser.org/oma/group/F1MB66/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F1LTK0-1", "protein_name": "Similar to human chromosome 2 open reading frame 78", "gene_name": "C1h2orf78", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSENFQSSPFFGTERARQLSLPVLSNSTQSAGRVCNISRVSTPDMNSPWLLPSASSTSLQPLMGNAYLNPHAGTTMLTVLTEQGQISTSAPSYPGALKWDFPGSRDGREEALQGVNVTIIDQDTTLSSLAITNQCDKILDPSAIVPFYPTLSASFVQVTPPQMPNQGYSLAPSYQDGSSQVYYYEHNSLGPLIAGEFGQCLQAHGSMPYPGSQTSAIQPEMVMVLKEIQPRNVQIPLFTSAFSYSTSAQSNSLPVVQMETSLGLPPSGQTHCQLQSPELYSTCAQVSQIRPSAVNGDRALTAPIHSPSEFLALPPAPSLEQTENKNVNEINDEFLKTLDAYEGTKENQDTSIVTLAHPDLQQPLQCADTEGLRPKSASDIAHLEGISMGPKKLGGLENEIRSSFDFKDISTLEADIQLPQLLNTLTDIDQDQACENWKVISGPSDQVRKNKHKSSEPLEGAPQAKIQHQDLVEGEASVCVAGTSNKAIENMAKHLEGKAPKVAANKNKRGRKQGQEKPSGPENNSKKTDELKQSRKRVKAEEKPTVPKTKRKRNPPELSQTSFKKPRTHLGMHMLESVQVFHPLGKKSEKKPGISSLGSLRTFTSNKDPGPSPVTTAVLNMSCEGQGPPKSPRKTQIAESSASKECPSQSQYELPPAGKVKLVPLPFPTLDKPQARPISRKPLSLASHRPTTVHPVQPHSHSAQLTTHRPSQLAPVSTSSMASTKPASPISSSATGPSGTNLIQSSAVPQVATSRPVPHRASSHTSFQRELVSAAKNKVPSPPKPQTQYLLQDFSRQPIPWKKVDILGPVVSQPITKEQRPEREAMKRRAQQERENAVKNTATGKLQLFLQREKDMEISQYYGYAM", "length": 866 }, "evidence": [ { "id": "F1MB66", "url": "https://omabrowser.org/oma/group/F1MB66/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "W4VSN8-1", "protein_name": "Predicted gene 5114", "gene_name": "Gm5114", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSENLQSSPFFGTESTLHPSLPLLSNSIQPAGTVCNFSRVSTPDVSSAWLLPSASSTSLQPLMGNAYLNPHAGTTMLTVLTEQGQISTSAPSYPGALKWDCTGSTHRREDALQDFNMTLIDQDTTLSSLAVTNQCDKILDPNVIVPFYPTLPASFVQVTPPQMLSQEYSLAPSYQEGSQVYYYEHNNLGPLITGEFGQCLQPHGSVSYPGSQTSVLQPEKVMVLQEIQPRNIQIPLFTSAFSYSTSAQSMPDNGLPVVQMEMSLGLPPSGQTHCQLQSPELCNTSVQVSQIRPPAVNGDRALTAPIHSPSQFLALCPAPSLEQSENKTMPEIKEGTKENQDTPILTLEHPDLQQPLHCTDTESLRQKPDSDNAHLGCIYMGPKELVGLEKEIGSSFDFKDITRFGADIQLPQLLNTLTDIDQDQSCENWRVTSGPSDQVRKNKHKSFELLEGDPQAKIQHWDLVEGEGAVGVAGASDRAIDNMAKHPEGKDPKVPPSKNRRARKQRQERPSVPENTSKKTEELKQSRNRVKAEEKPTIPKTKRKRNPPELSQNSFKKPRSNLAMHMLESVQVFHPLGKKIEKKTGISSFGGLRTSTNNKDPGPSSVTTTVLNMPGEGQGPPKSPGKLQRAESSVDKDCLSPSQYELPPAGKVKLVPLPFPTLDKPQSRPASRKPLSLALRRPTTVYPVQPHSHSAQPTTLRPAQPPPVSSSLIASAKPAPPISSSATGPNVTNPNQSSAVNQLATSRPVPYRASSHTSFQRELVSAARNKVPSPPKPQTQYLLHDFSRQPIPWKKVDILGPVVSQPITKEQRPEREAMKRRAQQERENAVKNPSTGKLQIFLQRERDMEISQYYGYAM", "length": 858 }, "evidence": [ { "id": "F1MB66", "url": "https://omabrowser.org/oma/group/F1MB66/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 491, "end_pos": 493, "annotation": "n_glycosylation_sequon" }, { "start_pos": 577, "end_pos": 579, "annotation": "n_glycosylation_sequon" }, { "start_pos": 584, "end_pos": 586, "annotation": "n_glycosylation_sequon" }, { "start_pos": 692, "end_pos": 694, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB66" }, { "id": "PF15442", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15442" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF4629", "eco_id": "ECO_0000259", "start_pos": 423, "end_pos": 570, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 100, "end_pos": 102 }, { "start_pos": 491, "end_pos": 493 }, { "start_pos": 577, "end_pos": 579 }, { "start_pos": 584, "end_pos": 586 }, { "start_pos": 692, "end_pos": 694 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BLU4-1", "uniprot_ac": "E1BLU4", "uniprot_id": "E1BLU4_BOVIN", "mass": { "chemical_mass": 221236.0, "monoisotopic_mass": 221236.0 }, "refseq": { "ac": "XP_010806816", "name": "CASP8-associated protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010806816" }, "gene_names": [ { "name": "CASP8AP2", "type": "recommended", "evidence": [ { "id": "E1BLU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLU4" } ] }, { "name": "CASP8AP2", "type": "synonym", "evidence": [ { "id": "XP_010806816", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010806816" } ] } ], "protein_names": [ { "name": "CASP8-associated protein 2", "type": "recommended", "evidence": [ { "id": "E1BLU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLU4/entry#names_and_taxonomy" } ] }, { "name": "CASP8-associated protein 2", "type": "synonym", "evidence": [ { "id": "XP_010806816", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010806816" } ] }, { "name": "FLICE-associated huge protein", "type": "synonym", "evidence": [ { "id": "E1BLU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLU4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Participates in TNF-induced blockade of glucocorticoid receptor (GR) transactivation at the nuclear receptor coactivator level, upstream and independently of NF-kappa-B. Suppresses both NCOA2- and NCOA3-induced enhancement of GR transactivation. Involved in TNF-induced activation of NF-kappa-B via a TRAF2-dependent pathway. Acts as a downstream mediator for CASP8-induced activation of NF-kappa-B. Required for the activation of CASP8 in FAS-mediated apoptosis. Involved for histone gene transcription and progression through S phase: required for the generation of mature histone mRNAs following the 3' end cleavage of histone pre-mRNAs.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1M7C3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7C3#function" }, { "database": "UniProtKB", "id": "ARBA00094258", "url": "https://www.uniprot.org/uniprotkb/ARBA00094258#function" }, { "database": "UniProtKB", "id": "A0AAA9S3W8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3W8#function" }, { "database": "UniProtKB", "id": "E1BLU4", "url": "https://www.uniprot.org/uniprotkb/E1BLU4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BLU4", "url": "https://www.uniprot.org/uniprotkb/E1BLU4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CASP8AP2", "url": "https://www.uniprot.org/uniprotkb/E1BLU4", "locus": { "chromosome": "9", "start_pos": 60368616, "end_pos": 60403731, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011313", "url": "https://www.ensembl.org/id/ENSBTAG00000011313" } ] } } ], "crossref": [ { "id": "ENSBTAG00000011313", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011313", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12202", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12202", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "505138", "url": "https://www.ncbi.nlm.nih.gov/gene/505138", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039674", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039674", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049257", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049257", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:505138", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505138", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HEKCKQQ", "url": "https://omabrowser.org/oma/group/HEKCKQQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BLU4", "url": "https://www.orthodb.org/?gene=E1BLU4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15489", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15489", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15489:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15489:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-3899300", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3899300", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_010806816", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010806816", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M7C3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7C3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M7C3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7C3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S3W8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3W8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S3W8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3W8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLU4", "url": "https://www.uniprot.org/uniprotkb/E1BLU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLU4-1", "url": "https://www.uniprot.org/uniprotkb/E1BLU4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAADDDNGDGTSLFDVFSASPLKNNDEGSLDIYAGLDSAGSDSASKSSVPSRNCLDLYEEILTEEGTAKEATYNDLQAEYGKCQLQMKELMKKFKEIQTQNFSLKNENQSLKKNISALIKTARVEINRKDEEINNLHQRLSEFPHFRNNHKTSRTSDLVKTKDLKSRSPHLDDSSKTDHRVKSDVSKDVHYSTSLPNHEKEGKSHCEKKSTLHLPTSVEKHSTNGIWSRFHYQVGESNSNEDHRRGRKDSRHSQYNRGTDRIRKDLSTSYGDGEPRNTEASQRLQGHPEKYGKGEPKAESKTAKLKSNTDLDYKNERISSSWEKESSRDKSHTRLESQSDKKLERQSERSQNVNRRELKSQDKEERKVDQKSKSVGKGQDHWRRSERAVLPHSKNEPSKSSHNSNKYHLEERRGWEDCKRDRAVSNHSFQEGRCPSSLLASRTHKHIDSTEVDSVHQRENAPFRAERHRTEEKRKRERENKEENKHIRNEDRVPPGHLQKTNKETKKTTADLKRQNEPKNGKGEVSNNDVSEGANNKEPAVRAESALNEPQNKDLKLSFMEKLNLTLSPAKKQPVSQDNQHTITDPPQSCDICDSESLVQAKTVTCVPSVSDHITEETKSELLEPKDALTAAFQPRTSISERKVEENSLSVASVENTVPCDTPICGTETSFSAPVEMEPSESSLSSSTEMKQTVNGARAAVPVKIDIVQTNVSQNVGLELDSKRNGDLNSCSISEEAEMKEAFSTNVTKSSESILQPSVEETDILPAVLSEGGTPKLEPSLVDPPLVENKSCHLDPCLPRETPESSLQQTELMDDTVEVGETNSVYHDDENSVLSIDFNQLRPIPEAISPLNSPVRPVAKVLRLESASQVPLYNNNHKDVFLPNSAHSTSMSQSDLNKENQKPICKSDKFAEADSHKNSSLDELEEGEIISDNEKPEPQRSFDKSAKPRASTEVQNTKTSPESRKSSVRLDKDNRKISSMKMHQTKSRWNRRRSESSRSSKTEKKERSMSTSSLEKIVPIIVTPSSVREIMHMLRMIRKHVRKNYMKFKVKFSLIQFHRIIESAILSFTSLIKYLDLSKISKSVTTLQKNLCDVIESKLKQVKKNGIVDRLFEQQLPDMKKKLWKFVDEQLDYLFTKLKKIFVKFCDSMNVGSDSDEGKLEKKSKEKARSSHCQKGNINNLGKEMLKEKSPKSEDYGSSKYSVGCKKSEEKHQEQKNSNSNTIKHDIKKTANTSFDNMKNPQSEAHSLEPNCLSTPKPGKIEGSATEDAQTSQLVPLKPERSFEILTEQQASSLTFNLVSDAQMGEIFKSLLQGSDLLDNSVNCNEKSEWELKTPEKQLLESLKCESIPACTTEELVSGVVSPCPKIISDDNWSLLSSEKGPSLSSGLSLPVHPDVLDENCMFEVSTNIALSKDNVCGSEKSKPYISSILLEDLAVSLTVPSPLKSDGHLSFLKPEALSNSTPEEVISAHFSEDALLEEEDASEQDIHLALESDNSSSKSSCSSSWTSRPVAPGFQYHPNLPMHAVIMEKSNDHFIVKIRRAAPSTSPTLVQNTVADEYLPRVEKEADEAVEEEYISCQNRVFKSVEELKNSSKNVDGRLVHEEQDCVIQTEVPDIYEFLKDASGKVSQSTEEAEECLKLHQVWEPKVPESIEELPPVEEIPHSVEDHLPSTCIDLTKDPVTETKKLGELVKVTVLNIDQLGCSGSSVDQNAPVLDNMQPETVDTFIDLTQDVSSDSKNEGNHPAIVVEDLGCPVICVDEDNSKEENVQVANRPLECIIEEACIDLTLEASSLDEVKKDDLNSESALNSNSSELPGMLDNPHKKRRNLSDLNPSSQKKQRKETDLTSREKTKKITQDSGENGNAHRRKASKKKAPSVTKDPSSLKESPGTKDASAASATSFTSLSAKNVIKKKGEIIVSWTRNDDREILLECQKKGPSLKTFTHLAAKLNKNPYQVSERFQQLMKLFEKSKCR", "length": 1973, "header": "tr|E1BLU4-1|E1BLU4_BOVIN Isoform 1 of CASP8-associated protein 2 OS=Bos taurus OX=9913 GN=CASP8AP2 PE=4 SV=1 CANONICAL=E1BLU4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M7C3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7C3/entry", "sequence": { "sequence": "MSGAPRKPRSSEAASGFSLQIPLWSFERIREGAGARTSAASPLKNNDEGSLDIYAGLDSAGSDSASKSSVPSRNCLDLYEEILTEEGTAKEATYNDLQAEYGKCQLQMKELMKKFKEIQTQNFSLKNENQSLKKNISALIKTARVEINRKDEEINNLHQRLSEFPHFRNNHKTSRTSDLVKTKDLKSRSPHLDDSSKTDHRVKSDVSKDVHYSTSLPNHEKEGKSHCEKKSTLHLPTSVEKHSTNGIWSRFHYQVGESNSNEDHRRGRKDSRHSQYNRGTDRIRKDLSTSYGDGEPRNTEASQRLQGHPEKYGKGEPKAESKTAKLKSNTDLDYKNERISSSWEKESSRDKSHTRLESQSDKKLERQSERSQNVNRRELKSQDKEERKVDQKSKSVGKGQDHWRRSERAVLPHSKNEPSKSSHNSNKYHLEERRGWEDCKRDRAVSNHSFQEGRCPSSLLASRTHKHIDSTEVDSVHQRENAPFRAERHRTEEKRKRERENKEENKHIRNEDRVPPGHLQKTNKETKKTTADLKRQNEPKNGKGEVSNNDVSEGANNKEPAVRAESALNEPQNKDLKLSFMEKLNLTLSPAKKQPVSQDNQHTITDPPQSCDICDSESLVQAKTVTCVPSVSDHITEETKSELLEPKDALTAAFQPRTSISERKVEENSLSVASVENTVPCDTPICGTETSFSAPVEMEPSESSLSSSTEMKQTVNGARAAVPVKIDIVQTNVSQNVGLELDSKRNGDLNSCSISEEAEMKEAFSTNVTKSSESILQPSVEETDILPAVLSEGGTPKLEPSLVDPPLVENKSCHLDPCLPRETPESSLQQTELMDDTVEVGETNSVYHDDENSVLSIDFNQLRPIPEAISPLNSPVRPVAKVLRLESASQVPLYNNNHKDVFLPNSAHSTSMSQSDLNKENQKPICKSDKFAEADSHKNSSLDELEEGEIISDNEKPEPQRSFDKSAKPRASTEVQNTKTSPESRKSSVRLDKDNRKISSMKMHQTKSRWNRRRSESSRSSKTEKKERSMSTSSLEKIVPIIVTPSSVREIMHMLRMIRKHVRKNYMKFKVKFSLIQFHRIIESAILSFTSLIKYLDLSKISKSVTTLQKNLCDVIESKLKQVKKNGIVDRLFEQQLPDMKKKLWKFVDEQLDYLFTKLKKIFVKFCDSMNVGSDSDEGKLEKKSKEKARSSHCQKGNINNLGKEMLKEKSPKSEDYGSSKYSVGCKKSEEKHQEQKNSNSNTIKHDIKKTANTSFDNMKNPQSEAHSLEPNCLSTPKPGKIEGSATEDAQTSQLVPLKPERSFEILTEQQASSLTFNLVSDAQMGEIFKSLLQGSDLLDNSVNCNEKSEWELKTPEKQLLESLKCESIPACTTEELVSGVVSPCPKIISDDNWSLLSSEKGPSLSSGLSLPVHPDVLDENCMFEVSTNIALSKDNVCGSEKSKPYISSILLEDLAVSLTVPSPLKSDGHLSFLKPEALSNSTPEEVISAHFSEDALLEEEDASEQDIHLALESDNSSSKSSCSSSWTSRPVAPGFQYHPNLPMHAVIMEKSNDHFIVKIRRAAPSTSPTLVQNTVADEYLPRVEKEADEAVEEEYISCQNRVFKSVEELKNSSKNVDGRLVHEEQDCVIQTEVPDIYEFLKDASGKVSQSTEEAEECLKLHQVWEPKVPESIEELPPVEEIPHSVEDHLPSTCIDLTKDPVTETKKLGELVKVTVLNIDQLGCSGSSVDQNAPVLDNMQPETVDTFIDLTQDVSSDSKNEGNHPAIVVEDLGCPVICVDEDNSKEENVQVANRPLECIIEEACIDLTLEASSLDEVKKDDLNSESALNSNSSELPGMLDNPHKKRRNLSDLNPSSQKKQRKETDLTSREKTKKITQDSGENGNAHRRKASKKKAPSVTKDPSSLKESPGTKDASAASATSFTSLSAKNVIKKKGEIIVSWTRNDDREILLECQKKGPSLKTFTHLAAKLNKNPYQVSERFQQLMKLFEKSKCR", "length": 1994, "header": "tr|A0A3Q1M7C3-1|A0A3Q1M7C3_BOVIN Computationally mapped isoform of CASP8-associated protein 2 OS=Bos taurus OX=9913 GN=CASP8AP2 PE=4 SV=1 CANONICAL=E1BLU4-1" }, "locus": { "chromosome": "9", "start_pos": 60403447, "end_pos": 60371213, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068923.2", "url": "https://www.ensembl.org/id/ENSBTAT00000068923.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064301.2", "url": "https://www.ensembl.org/id/ENSBTAP00000064301.2" } ] } }, { "isoform_ac": "A0AAA9S3W8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3W8/entry", "sequence": { "sequence": "MAADDDNGDGTSLFDVFSDSASKSSVPSRNCLDLYEEILTEEGTAKEATYNDLQAEYGKCQLQMKELMKKFKEIQTQNFSLKNENQSLKKNISALIKTARVEINRKDEEINNLHQRLSEFPHFRNNHKTSRTSDLVKTKDLKSRSPHLDDSSKTDHRVKSDVSKDVHYSTSLPNHEKEGKSHCEKKSTLHLPTSVEKHSTNGIWSRFHYQVGESNSNEDHRRGRKDSRHSQYNRGTDRIRKDLSTSYGDGEPRNTEASQRLQGHPEKYGKGEPKAESKTAKLKSNTDLDYKNERISSSWEKESSRDKSHTRLESQSDKKLERQSERSQNVNRRELKSQDKEERKVDQKSKSVGKGQDHWRRSERAVLPHSKNEPSKSSHNSNKYHLEERRGWEDCKRDRAVSNHSFQEGRCPSSLLASRTHKHIDSTEVDSVHQRENAPFRAERHRTEEKRKRERENKEENKHIRNEDRVPPGHLQKTNKETKKTTADLKRQNEPKNGKGEVSNNDVSEGANNKEPAVRAESALNEPQNKDLKLSFMEKLNLTLSPAKKQPVSQDNQHTITDPPQSCDICDSESLVQAKTVTCVPSVSDHITEETKSELLEPKDALTAAFQPRTSISERKVEENSLSVASVENTVPCDTPICGTETSFSAPVEMEPSESSLSSSTEMKQTVNGARAAVPVKIDIVQTNVSQNVGLELDSKRNGDLNSCSISEEAEMKEAFSTNVTKSSESILQPSVEETDILPAVLSEGGTPKLEPSLVDPPLVENKSCHLDPCLPRETPESSLQQTELMDDTVEVGETNSVYHDDENSVLSIDFNQLRPIPEAISPLNSPVRPVAKVLRLESASQVPLYNNNHKDVFLPNSAHSTSMSQSDLNKENQKPICKSDKFAEADSHKNSSLDELEEGEIISDNEKPEPQRSFDKSAKPRASTEVQNTKTSPESRKSSVRLDKDNRKISSMKMHQTKSRWNRRRSESSRSSKTEKKERSMSTSSLEKIVPIIVTPSSVREIMHMLRMIRKHVRKNYMKFKVKFSLIQFHRIIESAILSFTSLIKYLDLSKISKSVTTLQKNLCDVIESKLKQVKKNGIVDRLFEQQLPDMKKKLWKFVDEQLDYLFTKLKKIFVKFCDSMNVGSDSDEGKLEKKSKEKARSSHCQKGNINNLGKEMLKEKSPKSEDYGSSKYSVGCKKSEEKHQEQKNSNSNTIKHDIKKTANTSFDNMKNPQSEAHSLEPNCLSTPKPGKIEGSATEDAQTSQLVPLKPERSFEILTEQQASSLTFNLVSDAQMGEIFKSLLQGSDLLDNSVNCNEKSEWELKTPEKQLLESLKCESIPACTTEELVSGVVSPCPKIISDDNWSLLSSEKGPSLSSGLSLPVHPDVLDENCMFEVSTNIALSKDNVCGSEKSKPYISSILLEDLAVSLTVPSPLKSDGHLSFLKPEALSNSTPEEVISAHFSEDALLEEEDASEQDIHLALESDNSSSKSSCSSSWTSRPVAPGFQYHPNLPMHAVIMEKSNDHFIVKIRRAAPSTSPTLVQNTVADEYLPRVEKEADEAVEEEYISCQNRVFKSVEELKNSSKNVDGRLVHEEQDCVIQTEVPDIYEFLKDASGKVSQSTEEAEECLKLHQVWEPKVPESIEELPPVEEIPHSVEDHLPSTCIDLTKDPVTETKKLGELVKVTVLNIDQLGCSGSSVDQNAPVLDNMQPETVDTFIDLTQDVSSDSKNEGNHPAIVVEDLGCPVICVDEDNSKEENVQVANRPLECIIEEACIDLTLEASSLDEVKKDDLNSESALNSNSSELPGMLDNPHKKRRNLSDLNPSSQKKQRKETDLTSREKTKKITQDSGENGNAHRRKASKKKAPSVTKDPSSLKESPGTKDASAASATSFTSLSAKNVIKKKGEIIVSWTRNDDREILLECQKKGPSLKTFTHLAAKLNKNPYQVSERFQQLMKLFEKSKCR", "length": 1950, "header": "tr|A0AAA9S3W8-1|A0AAA9S3W8_BOVIN Computationally mapped isoform of CASP8-associated protein 2 OS=Bos taurus OX=9913 GN=CASP8AP2 PE=4 SV=1 CANONICAL=E1BLU4-1" }, "locus": { "chromosome": "9", "start_pos": 60388967, "end_pos": 60371213, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127450.1", "url": "https://www.ensembl.org/id/ENSBTAT00000127450.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079803.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079803.1" } ] } }, { "isoform_ac": "E1BLU4-1", "url": "https://www.uniprot.org/uniprotkb/E1BLU4/entry", "sequence": { "sequence": "MAADDDNGDGTSLFDVFSASPLKNNDEGSLDIYAGLDSAGSDSASKSSVPSRNCLDLYEEILTEEGTAKEATYNDLQAEYGKCQLQMKELMKKFKEIQTQNFSLKNENQSLKKNISALIKTARVEINRKDEEINNLHQRLSEFPHFRNNHKTSRTSDLVKTKDLKSRSPHLDDSSKTDHRVKSDVSKDVHYSTSLPNHEKEGKSHCEKKSTLHLPTSVEKHSTNGIWSRFHYQVGESNSNEDHRRGRKDSRHSQYNRGTDRIRKDLSTSYGDGEPRNTEASQRLQGHPEKYGKGEPKAESKTAKLKSNTDLDYKNERISSSWEKESSRDKSHTRLESQSDKKLERQSERSQNVNRRELKSQDKEERKVDQKSKSVGKGQDHWRRSERAVLPHSKNEPSKSSHNSNKYHLEERRGWEDCKRDRAVSNHSFQEGRCPSSLLASRTHKHIDSTEVDSVHQRENAPFRAERHRTEEKRKRERENKEENKHIRNEDRVPPGHLQKTNKETKKTTADLKRQNEPKNGKGEVSNNDVSEGANNKEPAVRAESALNEPQNKDLKLSFMEKLNLTLSPAKKQPVSQDNQHTITDPPQSCDICDSESLVQAKTVTCVPSVSDHITEETKSELLEPKDALTAAFQPRTSISERKVEENSLSVASVENTVPCDTPICGTETSFSAPVEMEPSESSLSSSTEMKQTVNGARAAVPVKIDIVQTNVSQNVGLELDSKRNGDLNSCSISEEAEMKEAFSTNVTKSSESILQPSVEETDILPAVLSEGGTPKLEPSLVDPPLVENKSCHLDPCLPRETPESSLQQTELMDDTVEVGETNSVYHDDENSVLSIDFNQLRPIPEAISPLNSPVRPVAKVLRLESASQVPLYNNNHKDVFLPNSAHSTSMSQSDLNKENQKPICKSDKFAEADSHKNSSLDELEEGEIISDNEKPEPQRSFDKSAKPRASTEVQNTKTSPESRKSSVRLDKDNRKISSMKMHQTKSRWNRRRSESSRSSKTEKKERSMSTSSLEKIVPIIVTPSSVREIMHMLRMIRKHVRKNYMKFKVKFSLIQFHRIIESAILSFTSLIKYLDLSKISKSVTTLQKNLCDVIESKLKQVKKNGIVDRLFEQQLPDMKKKLWKFVDEQLDYLFTKLKKIFVKFCDSMNVGSDSDEGKLEKKSKEKARSSHCQKGNINNLGKEMLKEKSPKSEDYGSSKYSVGCKKSEEKHQEQKNSNSNTIKHDIKKTANTSFDNMKNPQSEAHSLEPNCLSTPKPGKIEGSATEDAQTSQLVPLKPERSFEILTEQQASSLTFNLVSDAQMGEIFKSLLQGSDLLDNSVNCNEKSEWELKTPEKQLLESLKCESIPACTTEELVSGVVSPCPKIISDDNWSLLSSEKGPSLSSGLSLPVHPDVLDENCMFEVSTNIALSKDNVCGSEKSKPYISSILLEDLAVSLTVPSPLKSDGHLSFLKPEALSNSTPEEVISAHFSEDALLEEEDASEQDIHLALESDNSSSKSSCSSSWTSRPVAPGFQYHPNLPMHAVIMEKSNDHFIVKIRRAAPSTSPTLVQNTVADEYLPRVEKEADEAVEEEYISCQNRVFKSVEELKNSSKNVDGRLVHEEQDCVIQTEVPDIYEFLKDASGKVSQSTEEAEECLKLHQVWEPKVPESIEELPPVEEIPHSVEDHLPSTCIDLTKDPVTETKKLGELVKVTVLNIDQLGCSGSSVDQNAPVLDNMQPETVDTFIDLTQDVSSDSKNEGNHPAIVVEDLGCPVICVDEDNSKEENVQVANRPLECIIEEACIDLTLEASSLDEVKKDDLNSESALNSNSSELPGMLDNPHKKRRNLSDLNPSSQKKQRKETDLTSREKTKKITQDSGENGNAHRRKASKKKAPSVTKDPSSLKESPGTKDASAASATSFTSLSAKNVIKKKGEIIVSWTRNDDREILLECQKKGPSLKTFTHLAAKLNKNPYQVSERFQQLMKLFEKSKCR", "length": 1973, "header": "tr|E1BLU4-1|E1BLU4_BOVIN Isoform 1 of CASP8-associated protein 2 OS=Bos taurus OX=9913 GN=CASP8AP2 PE=4 SV=1 CANONICAL=E1BLU4-1" }, "locus": { "chromosome": "9", "start_pos": 60388967, "end_pos": 60369229, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015037.7", "url": "https://www.ensembl.org/id/ENSBTAT00000015037.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015037.5", "url": "https://www.ensembl.org/id/ENSBTAP00000015037.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:505138", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505138", "resource": "KEGG Pathway" }, { "id": "R-BTA-3899300", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3899300", "resource": "Reactome", "description": "SUMOylation of transcription cofactors" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XIV3-1", "protein_name": "CASP8-associated protein 2", "gene_name": "CASP8AP2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAADEDGLGLFDTRCAAEASPFKEGDESSVDIYDGLDNGLTVPDNSAPNSTPAGNSLNLFDEILIEEGTAKEASYNELQAEYGKCQQQIKELMKKLKEIQAQNIILQNENQALKKNISALIKTARVEINRKDEEISNLHQRLSEFPSHRSSFTRANLPGSTNGRCSEMCKTKDYKFRSSDLGDSIKADHRMKNDCSKDTYHSYSSHSVENGKSSSDKRNTPHAVRYPPEELCSNGTHTCPPNHDHSSNKDNKKEKKETKSDEEYSRRNVNKYKREVHQSTGNSGICNNTDSEERNSDPHQKLKAHSEKTSKNELQQKNQSIKVKCSPSTERKVEKSVSSWDKQTTGKDRCQARGELYAGERSLNVTKKDIKMHDKDEKNSSQKIKPNEKLQEQSRRSGRGNSPYSKNEHSKSLHESRKCRVEESRTGRDIDCKRDRGANDHSSREGRSSPSNSSSREHKYARFKENSSRYEWETAHSKSEKHRTEEKRKRERENQDENRHSRSERKVTKEISHQSAKKSKRDTDIKSERNKSYKSEETPGVTDSLKDHKFPQNKNHSVMKNKDLKLSFMEKLNLTLSPAKKQCLSPPDGLKVPSQMATDEGTTELTLHANMVDSGHLVNCGAAEQMNLTLEVPDTATKISVEPTLPVSVSSENEALKVTAADPAQSEALSAVTTCEVSSETLQEPVVDHIQSQALLGAAKVPIPDEMPAETLSAGAAAEACDPVELETSAVSVTDTNHPEASSQEVAGSVAQYENLSVTVCVMHSDNVPAAEMGQSKLDSEGMGTLPESALEKEEDEIWLAAGKKNSSAHQDSQNLVLCNLEAKSSADLESCDAADDTNETKRESSVEVVKDGDHLTVENLEPPAEEKAVCAISMNASQSPDRTVLNNIDVPLADQNACDVEPDLTDIGTTASSSITSEMYPRTKEKEPNPVPVDDDSSILSIDLNHLRHIPKAISPLNSPIRPLAKALKIESPCKGLVKSYNKDLIPEGTVVICPSKNLSKEVNKENQKPLSLSDAHIEIESQLSISSDEIEEGEIISSDEDEEKSKSEGHSENPQKSRPKTSPETRNLTSSPRNQKNKTIHCNEDNGKIVSVKVSTKNRAKHKNQTFRSSKEMKKNKTVSITCLEKIVQVIIEPSNVQEIMQMLRAIRKQMRKNYMKFKVHFPVQHFHRIIESAIINFTSLIKHLNFSKMSTSGETLKLNICDIIESKLKQVKKNAIVDRLFEQQVLDMKKRLWKFVDEQLDYLFEKVKRILVKQCDVIKLENESEEGKLERTGKQNHKISHKNDVQRSRKKSLKVRSQKPQEYILCNQSVDYQRPKCHHEKNKTDAPKAAFTKCLNSIDNTRNSQTKVQLTKENNLQYSLTPLKGIKHEKEGFQQFRDANKSDLSYDLLTEQQASTLTFNLVSDAQMGEIFKSLLQGSDLLEKSGSNIDRHDWEFRTPEKQFSDNHKCKTNTSELVQRIAPKEVHVESRSVEDISWAVVSPIRAPSLTSRLQMSVDPDVLDESCMFEVPTGATSCREDECSLQKSKSFVSSILLEDLAVSLTIPSPLKSDAHLSFLKSENNSSSTPECVLSAHYSEDALLEGEDATEQDIHLALESDNSSSRSSCSSSWTSRPVIPGFPCRSSLPMQAVIMEKSNDHFIVKIRRAVPSITPASDQMALVKEARASSTKNEKEEMRNGGKGRDRQSSIATTLQEPVKPDLLKMDQLSYVSIRKEQSPALPHPLKESQSSAGKEETTLLLGPRRKTSDVDSCDTESPSEGSEQPQTHKLEVSENIDGTSVGSQASFPVGCSVESDLTAESVKKTSCFAVESPANKRSQQVSTGNSEIRDKKELEECSDAFIDLTEDLSNETIAGECNLEEKSTLDTDGSCQISIDDKTSKKRKKETVEENSNLKRQRKETESADEGSNGSDVKSEGINSGQKQSQSKNNVLHQNKDSSPLSSGASSPGLYAKNIIKKKGEVVVSWTRNDDREILLECQRKGPSSKTFVSLATRLNKSPNQVSERFKQLMKLFKKSKCK", "length": 2019 }, "evidence": [ { "id": "E1BLU4", "url": "https://omabrowser.org/oma/group/E1BLU4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A7V6-1", "protein_name": "CASP8-associated protein 2", "gene_name": "Casp8ap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAADDDNGDGTGLFDVCPASPLKNNDEGSLDIYAGLDSTVSDSTARSCVSFRNCLDLYEEILTEEGTAKEATYSDLQIEYGKCQQQMKDLMKRFKEIQTQNLNLKNENQSLKKNISALIKTARVEINRKDEEINHLHQRLSEFPHFRNNHKTARTKDSRSKSPHLDNCSKTDHGVKSDVQKDIHPNTSQPNLEKEGKSHSEAQNSLHLSTGIEKHCTNNVWSRSPYQVSEGNSNEDNRRGRNGVRHSQGSRGTDRTQKDLNSSCNDGEPRDKEAASRLHGNPEKHGSSEARAENKISEIKSSTGLGNKSERSASSWEKETSRERPHTRVEPQNDKNLERQNERLQNTHRKELQSQDKAERKGDVKFKPAGEEQGHRGRVDRALPPHSKNDMKYYGFNKYHPEERRGREDGKRDRGMSSHGFQDRRCSSSLSSNRNSKYPHSKEVSVAHQWENTPFKAERHRTEDRRKRERENKEESRHVKSDKKSPPEHLQRTHKDTKKSTANGKRQTEQKHGKGPVSTSELSKGTDNRECTMKVENGPNEAKGKDLKLSFMEKLNLTLSPAKKQPVCQDNEHQIIGVPKPSGVCDSQSLEKTETVACLPSVSEQDREEPKSELPEPKEALSATSQPRTSIPENKVKEENRLLFKSVENTVPCELLACGTEISFPAPVEIEQARCLVQSMEVEETCAGARAAASVVMRVLPEHASEDFSQELGTKRHDDINSCDISEGGKKKVVLSPKAAAASESHLEPVVEEPSISPVNCSGDNNPKLEPSLEERPKVENKSSPLEPCLPKEMFVPSPQKTELIDHKIDTGESNSVYQDDDNSVLSIDFNNLRPIPEPISPLNSPVRPVSKVLSMESSCTIPLYDSSHKDEFPSNSTLSTFKSQSDLNKENEKPVPKLDKCSEAESCKNLSVDELEEGEIRSDDEESVAQKRLEKSARPRTSTEVPPGKISPGSRRSTVHVHKDNGRTVVKLPRDRITWSQRSNESRPSNTERKSKTMSISSLEKILPLILAPSSVWEVMHMLRLLGKHVRKNYMKFKIKFSLTQFHRIIESAILSFTSLIRYLDLSKICKSVSTLQKSLCDVIESNLKQVKKNGIVDRLFEQQQTDMKKKLWKFVDEQLDYLFEKLKKILLKFCDSVKHENDSSEGKLGKKYKERAQHSNCQKKKMDNKEIRREKVLKSENTVNFKSSLGCEKFEEKHQDQNKTNTTTVKHDVKRTFSTCTDNNTKNSECKEQFLGMNCPSTPRPGETEGNVEEGTPAAQHACVKSERGFEILTEQQASSLTFNLVSDAQMGEIFKSLLQGSDLLDTGGTEKAEWELKTPEKQLLESLKCESAPACTTEELVSEAASLCPKVISDDNWSLLSSEKGPSLSSGLSLPVHPDVLDENCMFEVSSNLALSKDNVYSSEKSKPCISSILLEDLAVSLTVPSPLKSDGHLSFLKPEVLSTSTPEEVISAHFSEDALLEEEDASEQDIHLALESDNSSSKSSCSSWTSRSVASGFQYHPNLPMHAVIMEKSNDHFIVKIRRATPSTSPGLKHGMVAEESLTPLPRTGKEADGAAEKEPTLFQSTVLNPVQDLENSDKSIDKSKPTHEDQNSIVQTQVPDIYEFLKDASNKVVHCDQVVDDCFKLHQVWEPKVSESLQELPSMEKNAHSVDDHLPNTHIDLTKDPATETKSLELMDVTVLDIDHLEHSKPNLDQDAQITCTSLQHDAVDAFIDLTHDVSNESKNESNEPVLTVEGVGCQVICIDDDNHKEGKVGKVNSSLECTVEETCIDLTSESAGSFEVKRHTLKSEPPSKSDCLELPETLGNGHKKRKNSPAVSHSSQKKQRKDMDLSSEKTKRLSPNSDRTGDAHRKHGSKKREPAVSDTSLSSEVNPEVKGSTAPLATFPGSLSAKNVIKKKGEIIVSWTRNDDREILLECQKRMPSLKTFTHLAVKLNKNPNQVSERFQQLKKLFEKSKCR", "length": 1962 }, "evidence": [ { "id": "E1BLU4", "url": "https://omabrowser.org/oma/group/E1BLU4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UKL3-1", "protein_name": "CASP8-associated protein 2", "gene_name": "CASP8AP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAADDDNGDGTSLFDVFSASPLKNNDEGSLDIYAGLDSAVSDSASKSCVPSRNCLDLYEEILTEEGTAKEATYNDLQVEYGKCQLQMKELMKKFKEIQTQNFSLINENQSLKKNISALIKTARVEINRKDEEISNLHQRLSEFPHFRNNHKTARTFDTVKTKDLKSRSPHLDDCSKTDHRAKSDVSKDVHHSTSLPNLEKEGKPHSDKRSTSHLPTSVEKHCTNGVWSRSHYQVGEGSSNEDSRRGRKDIRHSQFNRGTERVRKDLSTGCGDGEPRILEASQRLQGHPEKYGKGEPKTESKSSKFKSNSDSDYKGERINSSWEKETPGERSHSRVDSQSDKKLERQSERSQNINRKEVKSQDKEERKVDQKPKSVVKDQDHWRRSERASLPHSKNEITFSHNSSKYHLEERRGWEDCKRDKSVNSHSFQDGRCPSSLSNSRTHKNIDSKEVDAMHQWENTPLKAERHRTEDKRKREQESKEENRHIRNEKRVPTEHLQKTNKETKKTTTDLKKQNEPKTDKGEVLDNGVSEGADNKELAMKAESGPNETKNKDLKLSFMKKLNLTLSPAKKQPVSQDNQHKITDIPKSSGVCDSESSMQVKTVAYVPSISEHILGEAAVSEHTMGETKSTLLEPKVALLAVTEPRIGISETNKEDENSLLVRSVDNTMHCEEPICGTETSFPSPMEIQQTESLFPSTGMKQTINNGRAAAPVVMDVLQTDVSQNFGLELDTKRNDNSDYCGISEGMEMKVALSTTVSETTESILQPSIEEADILPIMLSEDNNPKFEPSVIVTPLVESKSCHLEPCLPKETLDSSLQQTELMDHRMATGETNSVYHDDDNSVLSIDLNHLRPIPEAISPLNSPVRPVAKVLRNESPPQVPVYNNSHKDVFLPNSAHSTSKSQSDLNKENQKPIYKSDKCTEADTCKNSPLDELEEGEIRSDSETSKPQESFEKNSKRRVSADVRKSKTIPRRGKSTVCLDKDSRKTHVRIHQTNNKWNKRPDKSSRSSKTEKKDKVMSTSSLEKIVPIIAVPSSEQEIMHMLRMIRKHVRKNYMKFKAKFSLIQFHRIIESAILSFTSLIKHLNLHKISKSVTTLQKNLCDIIESKLKQVKKNGIVDRLFEQQLPDMKKKLWKFVDDQLDYLFAKLKKILVCDSKSFGRDSDEGKLEKTSKQNAQYSNSQKRSVDNSNRELLKEKLSKSEDPVHYKSLVGCKKSEENYQDQNNSSINTVKHDIKKNFNICFDNIKNSQSEERSLEVHCPSTPKSEKNEGSSIEDAQTSQHATLKPERSFEILTEQQASSLTFNLVSDAQMGEIFKSLLQGSDLLDSSVNCTEKSEWELKTPEKQLLETLKCESIPACTTEELVSGVASPCPKMISDDNWSLLSSEKGPSLSSGLSLPVHPDVLDESCMFEVSTNLPLSKDNVCSVEKSKPCVSSILLEDLAVSLTVPSPLKSDGHLSFLKPDMSSSSTPEEVISAHFSEDALLEEEDASEQDIHLALESDNSSSKSSCSSSWTSRSVAPGFQYHPNLPMHAVIMEKSNDHFIVKIRRATPSTSSGLKQSMMPDELLTSLPRHGKEADEGPEKEYISCQNTVFKSVEELENSNKNVDGSKSTHEEQSSMIQTQVPDIYEFLKDASDKMGHSDEVADECFKLHQVWETKVPESIEELPSMEEISHSVGEHLPNTYVDLTKDPVTETKNLGEFIEVTVLHIDQLGCSGGNLNQSAQILDNSLQADTVGAFIDLTQDASSEAKSEGNHPALAVEDLGCGVIQVDEDNCKEEKAQVANRPLKCIVEETYIDLTTESPSSCEVKKDELKSEPGSNCDNSELPGTLHNSHKKRRNISDLNHPHKKQRKETDLTNKEKTKKPTQDSCENTEAHQKKASKKKAPPVTKDPSSLKATPGIKDSSAALATSTSLSAKNVIKKKGEIIILWTRNDDREILLECQKRGPSFKTFAYLAAKLDKNPNQVSERFQQLMKLFEKSKCR", "length": 1982 }, "evidence": [ { "id": "E1BLU4", "url": "https://omabrowser.org/oma/group/E1BLU4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WUF3-1", "protein_name": "CASP8-associated protein 2", "gene_name": "Casp8ap2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAADDDNGDGTGLFDVCPASPLKNNDEGSLDIYAGLDSAVSDSTARSCVSFRNCLDLYEEILTEEGTAKEATYNDLQIEYGKCQQQMKDLMKRFKEIQTQNLNLKNENQSLKKNISALIKTARVEINRKDEEINHLHQRLSEFPHFRNNHKTARTKDSQSTSPHLDDCSKTDHGVKSDVQKDVHPNTAQPNLEKEGKSHSEAQNPLHLSTGVEKHCANNVWSRSPYQVGEGNSNEDNRRGRSGTRHSQCSRGTDRTQKDLHSSCNDSEPRDKEANSRLQGHPEKHGNSEARTESKISESKSSTGMGYKSERSASSWEKETSRERPHTRVESQHDKNLEKQNERLQNMHRKELPSQDKTERKVDVKFKPAGEEQGHRGRVDRALPPHPKNDVKHYGFNKYHPEERRGREDCKRDRGMNSHGFQDRRCSSFLSSNRNSKYPHSKEVSVAHQWENTPFKAERHRTEDRRKRERENKEESRHVKSDKKSPPEHLQRTHKDTKKSTADGKRQTEPKHGKGAVSNSELSKGTDSKEGATKVESGPNEAKGKDLKLSFMEKLNLTLSPAKKQPACQDNPHQITGVPEPSGTCDSRSLETTGTVACLPSGSEHNREETKSELPEPKEALLATSQLRISIPENKMKEEKRLLFKSVENTVPCELLACGTEISLPAPVEIEQARCLLGSVEVEETCGGARTAASVVMHVLPEHASEDASQELDTKRHDGINACAISEGVKTKVILSPKAAAASESHLAPLVEEPSISLVNCSGDNNPKLEPSLEERPIVETKSCPLESCLPKETFVPSPQKTELIDHKIETGESNSVYQDDDNSVLSIDFNNLRPIPDPISPLNSPVRPVCKVVSMESSCAIPLYDSSHKDEFPSNSTLSTFKSQSDLNKENEKPVPKFDKCSEADSCKHLSLDELEEGEIRSDDEESVAQKRLEKSARPRVSAEVQPGKSSPGSRRSTVHVHKDNGRTAVKLPRDRLTWSKRSSESRPSNTERKSKTMSISSLEKILPLILVPSSLWEVMHMLRLLGKHVRKNYMKFKIKFSLTQFHRIIESAILSFTSLVKCLDLSKICKSVSTLQKSLCEVIESNLKQVKKNGIVDRLFEQQQTDMKKKLWKFVDEQLDYLFEKLKKILLKFCDSVNFENENSEGKLGKKYKERTQHSNCQKKKMDNKEIRREKVLKSENTVNFKSSLGCEKSEEKHQDQNKTNASIVKHDVKRTFSTCSDNTKNAECKEQFLEKSCPSTPRPGKDEGHTEEEAQAAQHASAKSERSFEILTEQQASSLTFNLVSDAQMGEIFKSLLQGSDLLDTSGTEKAEWELKTPEKQLLESLKCESAPACATEELVSEGASLCPKVISDDNWSLLSSEKGPSLSSGLSLPVHPDVLDENCMFEVSSNTALGKDNVYSSEKSKPCISSILLEDLAVSLTVPSPLKSDGHLSFLKPEVLSTSTPEEVISAHFSEDALLEEEDASEQDIHLALESDNSSSKSSCSSWTSRSVASGFQYHPNLPMHAVIMEKSNDHFIVKIRRATPSTSPGLKHGVVAEESLTSLPRTGKEAGVATEKEPNLFQSTVLKPVKDLENTDKNIDKSKLTHEEQNSIVQTQVPDIYEFLKDASNKVVHCDQVVDDCFKLHQVWEPKVSENLQELPSMEKIPHSLDNHLPDTHIDLTKDSATETKSLGELMEVTVLNVDHLECSQTNLDQDAEITCSSLQPDTIDAFIDLTHDASSESKNEGSEPVLAVEGMGCQVICIDEDTNKEGKMGRANSPLESIVEETCIDLTSESPGSCEIKRHNLKSEPPSKLDCLELPETLGNGHKKRKNSPGVSHSSQKKQRKDIDLSSEKTQRLSPNSDRNGDAHRKQASKKREPAVNETSLSSEASPEVKGSTAVLAASPASLSAKNVIKKKGEIIVSWTRNDDREILLECQKRMPSLKTFTYLAVKLNKNPNQVSERFQQLKKLFEKSKCR", "length": 1962 }, "evidence": [ { "id": "E1BLU4", "url": "https://omabrowser.org/oma/group/E1BLU4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "E1BLU4", "url": "https://www.uniprot.org/uniprotkb/E1BLU4" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "E1BLU4", "url": "https://www.uniprot.org/uniprotkb/E1BLU4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BLU4", "url": "https://www.uniprot.org/uniprotkb/E1BLU4" } ], "pmid": "" }, { "name": "extrinsic apoptotic signaling pathway via death domain receptors", "id": "GO:0008625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008625", "evidence": [ { "database": "UniProtKB", "id": "E1BLU4", "url": "https://www.uniprot.org/uniprotkb/E1BLU4" } ], "pmid": "" }, { "name": "Fas signaling pathway", "id": "GO:0036337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036337", "evidence": [ { "database": "UniProtKB", "id": "E1BLU4", "url": "https://www.uniprot.org/uniprotkb/E1BLU4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "E1BLU4", "url": "https://www.uniprot.org/uniprotkb/E1BLU4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1232, "end_pos": 1234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1372, "end_pos": 1374, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1460, "end_pos": 1462, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1495, "end_pos": 1497, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1591, "end_pos": 1593, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1810, "end_pos": 1812, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1827, "end_pos": 1829, "annotation": "n_glycosylation_sequon" }, { "start_pos": 426, "end_pos": 428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 564, "end_pos": 566, "annotation": "n_glycosylation_sequon" }, { "start_pos": 711, "end_pos": 713, "annotation": "n_glycosylation_sequon" }, { "start_pos": 746, "end_pos": 748, "annotation": "n_glycosylation_sequon" }, { "start_pos": 789, "end_pos": 791, "annotation": "n_glycosylation_sequon" }, { "start_pos": 918, "end_pos": 920, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 108, "end_pos": 110 }, { "start_pos": 114, "end_pos": 116 }, { "start_pos": 1232, "end_pos": 1234 }, { "start_pos": 1372, "end_pos": 1374 }, { "start_pos": 1460, "end_pos": 1462 }, { "start_pos": 1495, "end_pos": 1497 }, { "start_pos": 1591, "end_pos": 1593 }, { "start_pos": 1810, "end_pos": 1812 }, { "start_pos": 1827, "end_pos": 1829 }, { "start_pos": 426, "end_pos": 428 }, { "start_pos": 564, "end_pos": 566 }, { "start_pos": 711, "end_pos": 713 }, { "start_pos": 746, "end_pos": 748 }, { "start_pos": 789, "end_pos": 791 }, { "start_pos": 918, "end_pos": 920 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKWLNKYFSLGNSKTKSPPQPPRPDYREQRRRGERPSQPPQAVPQAPAAASASCGTAAASCFSASSGSLPDDSGSTSDLIRAYRAQKERDFEDPYNGPGSSLRKLRAMCRLDYCGGGEPGGSQRAFSASSASGAAGCCCASSGAGAAASSSSSSGSPHLYRSSSERRPATPAEVRYISPKHRLIKVESAAGCAGDPPGGACSGGRTWSPTACGGKKLLNKCGASAAEESGAGKKDKVTIADDYSDPFDAKNDLKSKTGKGESAGYMEPYEAQRIMTEFQRQESVRSQHKGIQLYDTPYEPEGQSVDSDSESTISPRLRESKLPQDDDRPADEYDQPWEWNRVTIPALAAQFNGSEKRQSSPSPSRDRRRQLRAPGGGFKPIKHGSPEFCGILGERVDPAVPLEKQIWYHGAISRGDAENLLRLCKECSYLVRNSQTSRHDYSLSLKSNQGFMHMKLAKTKEKYVLGQNSPPFDSVPEVIHYYTTRKLPIKGAEHLSLLYPVAVRTL", "length": 507, "header": "tr|E1BLY9-1|E1BLY9_BOVIN Isoform 1 of SH2 domain containing adaptor protein B OS=Bos taurus OX=9913 GN=SHB PE=4 SV=1 CANONICAL=E1BLY9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TK77-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TK77/entry", "sequence": { "sequence": "MAKWLNKYFSLGNSKTKSPPQPPRPDYREQRRRGERPSQPPQAVPQAPAAASASCGTAAASCFSASSGSLPDDSGSTSDLIRAYRAQKERDFEDPYNGPGSSLRKLRAMCRLDYCGGGEPGGSQRAFSASSASGAAGCCCASSGAGAAASSSSSSGSPHLYRSSSERRPATPAEVRYISPKHRLIKVESAAGCAGDPPGGACSGGRTWSPTACGGKKLLNKCGASAAEESGAGKKDKVTIADDYSDPFDAKNDLKSKTGKGESAGYMEPYEAQRIMTEFQRQESVRSQHKGIQLYDTPYEPEGQSVDSDSESTISPRLRESKLPQDDDRPADEYDQPWEWNRVTIPALAAQFNGSEKRQSSPSPSRDRRRQLRAPGGGFKPIKHGSPEFCGILGERVDPAVPLEKQIWYHGAISRGDAENLLRLCKECSYLVRNSQTSRHDYSLSLKIEEDEKEQGAWGLVPISERPGPCNQKSLESSRSKPWLSHERNRRRKGKGPSQGPAASCWWSPDVSTPIQGYYPSEAP", "length": 524, "header": "tr|A0AAA9TK77-1|A0AAA9TK77_BOVIN Computationally mapped isoform of SH2 domain containing adaptor protein B OS=Bos taurus OX=9913 GN=SHB PE=4 SV=1 CANONICAL=E1BLY9-1" }, "locus": { "chromosome": "8", "start_pos": 62143954, "end_pos": 62020895, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097619.1", "url": "https://www.ensembl.org/id/ENSBTAT00000097619.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098777.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098777.1" } ] } }, { "isoform_ac": "A0AAA9U0Q6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0Q6/entry", "sequence": { "sequence": "MAKWLNKYFSLGNSKTKSPPQPPRPDYREQRRRGERPSQPPQAVPQAPAAASASCGTAAASCFSASSGSLPDDSGSTSDLIRAYRAQKERDFEDPYNGPGSSLRKLRAMCRLDYCGGGEPGGSQRAFSASSASGAAGCCCASSGAGAAASSSSSSGSPHLYRSSSERRPATPAEVRYISPKHRLIKVESAAGCAGDPPGGACSGGRTWSPTACGGKKLLNKCGASAAEESGAGKKDKVTIADDYSDPFDAKNDLKSKTGKGESAGYMEPYEAQRIMTEFQRQESVRSQHKGIQLYDTPYEPEGQSVDSDSESTISPRLRESKLPQDDDRPADEYDQPWEWNRVTIPALAAQFNGSEKRQSSPSPSRDRRRQLRAPGGGFKPIKHGSPEFCGILGERVDPAVPLEKQIWYHGAISRGDAENLLRLCKECSYLVRNSQTSRHDYSLSLKSNQGFMHMKLAKTKEKYVLGQNSPPFDSVPEVIHYYTTRKLPIKGAEHLSLLYPVAGRGGSSRVAALCSPAVRNSHLCTGPQFSPPGPPWCWEPSAGVLRAQKAPESHLPSGVCVSVCVCVCVCVCVCVCVCVCARAYWWKNTTTHRCKPTNPLLVTQCNH", "length": 608, "header": "tr|A0AAA9U0Q6-1|A0AAA9U0Q6_BOVIN Computationally mapped isoform of SH2 domain containing adaptor protein B OS=Bos taurus OX=9913 GN=SHB PE=4 SV=1 CANONICAL=E1BLY9-1" }, "locus": { "chromosome": "8", "start_pos": 62143954, "end_pos": 62008789, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104818.1", "url": "https://www.ensembl.org/id/ENSBTAT00000104818.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102683.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102683.1" } ] } }, { "isoform_ac": "E1BLY9-1", "url": "https://www.uniprot.org/uniprotkb/E1BLY9/entry", "sequence": { "sequence": "MAKWLNKYFSLGNSKTKSPPQPPRPDYREQRRRGERPSQPPQAVPQAPAAASASCGTAAASCFSASSGSLPDDSGSTSDLIRAYRAQKERDFEDPYNGPGSSLRKLRAMCRLDYCGGGEPGGSQRAFSASSASGAAGCCCASSGAGAAASSSSSSGSPHLYRSSSERRPATPAEVRYISPKHRLIKVESAAGCAGDPPGGACSGGRTWSPTACGGKKLLNKCGASAAEESGAGKKDKVTIADDYSDPFDAKNDLKSKTGKGESAGYMEPYEAQRIMTEFQRQESVRSQHKGIQLYDTPYEPEGQSVDSDSESTISPRLRESKLPQDDDRPADEYDQPWEWNRVTIPALAAQFNGSEKRQSSPSPSRDRRRQLRAPGGGFKPIKHGSPEFCGILGERVDPAVPLEKQIWYHGAISRGDAENLLRLCKECSYLVRNSQTSRHDYSLSLKSNQGFMHMKLAKTKEKYVLGQNSPPFDSVPEVIHYYTTRKLPIKGAEHLSLLYPVAVRTL", "length": 507, "header": "tr|E1BLY9-1|E1BLY9_BOVIN Isoform 1 of SH2 domain containing adaptor protein B OS=Bos taurus OX=9913 GN=SHB PE=4 SV=1 CANONICAL=E1BLY9-1" }, "locus": { "chromosome": "8", "start_pos": 62143954, "end_pos": 62009396, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000034285.6", "url": "https://www.ensembl.org/id/ENSBTAT00000034285.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000034182.4", "url": "https://www.ensembl.org/id/ENSBTAP00000034182.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:538275", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538275", "resource": "KEGG Pathway" }, { "id": "R-BTA-4420097", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4420097", "resource": "Reactome", "description": "VEGFA-VEGFR2 Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZN31-1", "protein_name": "SH2 domain containing adaptor protein B", "gene_name": "Shb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKWLNKYFSLGNSKTKSPPQPPRPDYREQRRRGERREQPPQAVPQACSASSASCGSAAACFSASSGSLPDDSGSTSDLIRAYRAQKERDFEDPYNGPGSSLRKLRAMCRLDYCGGGGDPGGGQRAFTAAAGAAGCCCAAAGAGAAASSSSSSGSPHLYRSSSERRPATPAEVRYISPKHRLIKVESAGAAGDPPGGVCSGGRTWSPTTCGGKKLLNKCAAEETGAGQKDKVTIADDYSDPFDAKNDLKSKAGKGESAGYMEPYEAQRIMTEFQRQESVRSQHKGIQLYDTPYEPEGQSVDSDSESTVSLRLRESKLPQDDDRPADEYDQPWEWNRVTIPALAAQFNGNEKRQSSPSPSRDRRRQLRAPGGGFKPIKHGSPEFCGILGERVDPTIPLEKQIWYHGAISRSDAENLLRLCKECSYLVRNSQTSKHDYSLSLKSNQGFMHMKLAKTKDKYVLGQNSPPFDSVPEVIHYYTTRKLPIKGAEHLSLLYPVAVRTL", "length": 501 }, "evidence": [ { "id": "E1BLY9", "url": "https://omabrowser.org/oma/group/E1BLY9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1ST57-1", "protein_name": "SH2 domain containing adaptor protein B", "gene_name": "SHB", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAKWLNKYFSLGNSKTKSPPQPPRPDYREQRRRGERPSQPPQAVPQAPAAASASCGTAAASCFSASSGSLPDDSGSTSDLIRAYRAQKERDFEDPYNGPGSSLRKLRAMCRLDYCGGGEPGGGQRAFSASSASGASGCCCASSGAGAAASSSSSSGSPHLYRSSSERRPATPAEVRYISPKHRLIKVESAAGGAGDPPGGACSGGRTWSPTACGGKKLLNKCGASATEESSAGKKDKVTIADDYSDPFDAKNDLKNKAGKGESAGYMEPYEAQRIMTEFQRQESVRSQHKGIQLYDTPYEPEGQSVDSDSESTVSPRLRESKLPQDDDRPADEYDQPWEWNRVTIPALAAQFNGNEKRQSSPSPSRDRRRQLRAPGGGFKPIKHGSPEFCGILGERVDPSVPLEKQIWYHGAISRGDAENLLRLCKECSYLVRNSQTSRHDYSLSLKSNQGFMHMKLAKTKEKYVLGQNSPPFDSVPEVIHYYTTRKLPIKGAEHLSLLYPVAVRTL", "length": 507 }, "evidence": [ { "id": "E1BLY9", "url": "https://omabrowser.org/oma/group/E1BLY9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q15464-1", "protein_name": "SH2 domain-containing adapter protein B", "gene_name": "SHB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKWLNKYFSLGNSKTKSPPQPPRPDYREQRRRGERPSQPPQAVPQASSAASASCGPATASCFSASSGSLPDDSGSTSDLIRAYRAQKERDFEDPYNGPGSSLRKLRAMCRLDYCGGSGEPGGVQRAFSASSASGAAGCCCASSGAGAAASSSSSSGSPHLYRSSSERRPATPAEVRYISPKHRLIKVESAAGGGAGDPLGGACAGGRTWSPTACGGKKLLNKCAASAAEESGAGKKDKVTIADDYSDPFDAKNDLKSKAGKGESAGYMEPYEAQRIMTEFQRQESVRSQHKGIQLYDTPYEPEGQSVDSDSESTVSPRLRESKLPQDDDRPADEYDQPWEWNRVTIPALAAQFNGNEKRQSSPSPSRDRRRQLRAPGGGFKPIKHGSPEFCGILGERVDPAVPLEKQIWYHGAISRGDAENLLRLCKECSYLVRNSQTSKHDYSLSLRSNQGFMHMKLAKTKEKYVLGQNSPPFDSVPEVIHYYTTRKLPIKGAEHLSLLYPVAVRTL", "length": 509 }, "evidence": [ { "id": "E1BLY9", "url": "https://omabrowser.org/oma/group/E1BLY9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6PD21-1", "protein_name": "SH2 domain-containing adapter protein B", "gene_name": "Shb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKWLNKYFSLGNSKTKSPPQPPRPDYREQRRRGERREQPPQAVPQACSASSASCGSAAACFSASSGSLPDDSGSTSDLIRAYRAQKERDFEDPYNGPGSSLRKLRAMCRLDYCGGGGGGDPGGGQRAFTAAAGAAGCCCAAAGAGAAASSSSSSGSPHLYRSSSERRPTTPAEVRYISPKHRLIKVESASAAGDPPGGVCSGGRTWSPTTCGGKKLLNKCSAEETGAGQKDKVTIADDYSDPFDAKSDLKSKAGKGESAGYMEPYEAQRIMTEFQRQESVRSQHKGIQLYDTPYEPEGQSVDSDSESTVSLRLRESKLPQDDDRPADEYDQPWEWNRVTIPALAAQFNGNEKRQSSPSPSRDRRRQLRAPGGGFKPIKHGSPEFCGILGERVDPTIPLEKQIWYHGAISRSDAENLLRLCKECSYLVRNSQTSKHDYSLSLKSNQGFMHMKLAKTKEKYVLGQNSPPFDSVPEVIHYYTTRKLPIKGAEHLSLLYPVAVRTL", "length": 503 }, "evidence": [ { "id": "E1BLY9", "url": "https://omabrowser.org/oma/group/E1BLY9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "R4GGM0-1", "protein_name": "SH2 domain containing adaptor protein B", "gene_name": "SHB", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAKWLNKYFSLGNNKTKSPPQPPRPDYREKRNGAGGAPRPDGPPHLHRHQHHTSPGFPHRHLRDDTSELLRAYRAQKDRDFEDPYSGPGSSLRKLRALCRPEPCAPDEPGPAAPRAFSSASCGAAASAPAGSPLLARSQSERRPGTPPEVRYISPRHRLIRVEIGDGGRFGRGGEQLAASAPAKEKVLIADDYSDPFDAKSELNKMVKGENTGYMEPYEAQRIMTEFQKQEGMKTHQKNMQLYDTPYEPEGSGVESDSESVVSQRLRESKLPQDDDRPADEYDQPWEWNKVTIPALAAQFNGSEKRQASPSSSNDQRRQLRAPGRGFKPIKHGSPEFCGILGERIDPTVPLEKQIWYHGAISRTDAENLLRLCKECSYLVRNSQTSKHDYSLSLKSSQGFMHMKLTKTKEKYILGQNSPPFDSVPEVIHYYTTKKLPIKGAEHLSLLYPVAVRTL", "length": 455 }, "evidence": [ { "id": "E1BLY9", "url": "https://omabrowser.org/oma/group/E1BLY9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phosphotyrosine residue binding", "id": "GO:0001784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001784", "evidence": [ { "database": "UniProtKB", "id": "E1BLY9", "url": "https://www.uniprot.org/uniprotkb/E1BLY9" } ], "pmid": "" }, { "name": "signaling receptor complex adaptor activity", "id": "GO:0030159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030159", "evidence": [ { "database": "UniProtKB", "id": "E1BLY9", "url": "https://www.uniprot.org/uniprotkb/E1BLY9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "E1BLY9", "url": "https://www.uniprot.org/uniprotkb/E1BLY9" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "E1BLY9", "url": "https://www.uniprot.org/uniprotkb/E1BLY9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BLY9", "url": "https://www.uniprot.org/uniprotkb/E1BLY9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 353, "end_pos": 355, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BLY9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 507, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BLY9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BLY9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BLY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLY9" }, { "id": "PS50001", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50001" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH2", "eco_id": "ECO_0000259", "start_pos": 408, "end_pos": 502, "start_aa": "Trp", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 353, "end_pos": 355 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BLZ7-1", "uniprot_ac": "E1BLZ7", "uniprot_id": "E1BLZ7_BOVIN", "mass": { "chemical_mass": 21648.0, "monoisotopic_mass": 21648.0 }, "refseq": { "ac": "NP_001178127", "name": "low-density lipoprotein receptor class A domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178127" }, "gene_names": [ { "name": "LDLRAD1", "type": "recommended", "evidence": [ { "id": "E1BLZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLZ7" } ] }, { "name": "LDLRAD1", "type": "synonym", "evidence": [ { "id": "NP_001178127", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178127" } ] } ], "protein_names": [ { "name": "Low density lipoprotein receptor class A domain containing 1", "type": "synonym", "evidence": [ { "id": "E1BLZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLZ7/entry#names_and_taxonomy" } ] }, { "name": "low-density lipoprotein receptor class A domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001178127", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178127" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BLZ7", "url": "https://www.uniprot.org/uniprotkb/E1BLZ7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LDLRAD1", "url": "https://www.uniprot.org/uniprotkb/E1BLZ7", "locus": { "chromosome": "3", "start_pos": 92221924, "end_pos": 92211210, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000024195", "url": "https://www.ensembl.org/id/ENSBTAG00000024195" } ] } } ], "crossref": [ { "id": "E1BLZ7", "url": "https://alphafold.ebi.ac.uk/entry/E1BLZ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000024195", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000024195", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "784181", "url": "https://www.ncbi.nlm.nih.gov/gene/784181", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002172", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002172", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050685", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050685", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051221", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051221", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057430", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057430", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:784181", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:784181", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MCRDMPQ", "url": "https://omabrowser.org/oma/group/MCRDMPQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR22722", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22722", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22722:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22722:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24270", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24270", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25241", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25241", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001178127", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178127", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9RSR4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RSR4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSR4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T736", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T736", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T736-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T736-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLZ7", "url": "https://www.uniprot.org/uniprotkb/E1BLZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLZ7-1", "url": "https://www.uniprot.org/uniprotkb/E1BLZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNKIFPQGDANGSAAAGSKALPGGEANCSPCCCSRRGACLSAFLMLLLTALAALIALVAILGPPPRTPGAQACVTQTNRTGFLCDDRSSCIPASSVCDGVRACAHGEDEEEALCRGVPQSLSGFLVAHCGDPASWIYSDQMCDGINNCGDCSDELSPVTTCPPCGPGWWRCPSTVFRYCSCIPRSLCRDHVQHCFDWSDEYSCPGP", "length": 206, "header": "tr|E1BLZ7-1|E1BLZ7_BOVIN Isoform 1 of Low density lipoprotein receptor class A domain containing 1 OS=Bos taurus OX=9913 GN=LDLRAD1 PE=4 SV=2 CANONICAL=E1BLZ7-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RSR4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSR4/entry", "sequence": { "sequence": "MNKIFPQGDANGSAAAGSKALPGGEGGVPQSLSGFLVAHCGDPASWIYSDQMCDGINNCGDCSDELSPVTTCPPCGPGWWRCPSTVFRYCSCIPRSLCRDHVQHCFDWSDEYSCPGP", "length": 117, "header": "tr|A0AAA9RSR4-1|A0AAA9RSR4_BOVIN Computationally mapped isoform of Low density lipoprotein receptor class A domain containing 1 OS=Bos taurus OX=9913 GN=LDLRAD1 PE=4 SV=1 CANONICAL=E1BLZ7-1" }, "locus": { "chromosome": "3", "start_pos": 92220920, "end_pos": 92211535, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000121298.1", "url": "https://www.ensembl.org/id/ENSBTAT00000121298.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075728.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075728.1" } ] } }, { "isoform_ac": "A0AAA9T736-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T736/entry", "sequence": { "sequence": "MNKIFPQGDANGSAAAGSKALPGGEGAQACVTQTNRTGFLCDDRSSCIPASSVCDGVRACAHGEDEEEALCRGVPQSLSGFLVAHCGDPASWIYSDQMCDGINNCGDCSDELSPVTTCPPCGPGWWRCPSTVFRYCSCIPRSLCRDHVQHCFDWSDEYSCPGP", "length": 163, "header": "tr|A0AAA9T736-1|A0AAA9T736_BOVIN Computationally mapped isoform of Low density lipoprotein receptor class A domain containing 1 OS=Bos taurus OX=9913 GN=LDLRAD1 PE=4 SV=1 CANONICAL=E1BLZ7-1" }, "locus": { "chromosome": "3", "start_pos": 92220920, "end_pos": 92211535, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000107734.1", "url": "https://www.ensembl.org/id/ENSBTAT00000107734.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092416.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092416.1" } ] } }, { "isoform_ac": "E1BLZ7-1", "url": "https://www.uniprot.org/uniprotkb/E1BLZ7/entry", "sequence": { "sequence": "MNKIFPQGDANGSAAAGSKALPGGEANCSPCCCSRRGACLSAFLMLLLTALAALIALVAILGPPPRTPGAQACVTQTNRTGFLCDDRSSCIPASSVCDGVRACAHGEDEEEALCRGVPQSLSGFLVAHCGDPASWIYSDQMCDGINNCGDCSDELSPVTTCPPCGPGWWRCPSTVFRYCSCIPRSLCRDHVQHCFDWSDEYSCPGP", "length": 206, "header": "tr|E1BLZ7-1|E1BLZ7_BOVIN Isoform 1 of Low density lipoprotein receptor class A domain containing 1 OS=Bos taurus OX=9913 GN=LDLRAD1 PE=4 SV=2 CANONICAL=E1BLZ7-1" }, "locus": { "chromosome": "3", "start_pos": 92220920, "end_pos": 92211535, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000043254.4", "url": "https://www.ensembl.org/id/ENSBTAT00000043254.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000040841.3", "url": "https://www.ensembl.org/id/ENSBTAP00000040841.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:784181", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:784181", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1A2C1-1", "protein_name": "Low density lipoprotein receptor class A domain containing 1", "gene_name": "LDLRAD1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNKTHPQRNGDVTTFDSAKSSSEEQGCCRPRCARLCCPPRQACVVLLLLAAIAAIMGLAIALGLQPRALVNRPCVATHNWTGFLCNDRVTCIPASQVCDGTANCRNGEDEQEKLCGDLPRSLPAYLVFHCGNPEYWVYADQRCNGMNDCGDCSDEMGRLAACPPCGPAWWSCSPVHYEYCSCVPRALCRDGVQHCLSWSDEYLCRP", "length": 206 }, "evidence": [ { "id": "E1BLZ7", "url": "https://omabrowser.org/oma/group/E1BLZ7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3YYZ1-1", "protein_name": "Low density lipoprotein receptor class A domain containing 1", "gene_name": "Ldlrad1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVGCERAEFCPACFWFLGQADAESNITTRRKARPGDEGCGPLCCSRRGACLSVGLLLLLAMLAALLAVATILGHPPRTPETHSCVTLANRTGFLCHDRRHCIPAHAVCDGIRTCPHGEDEAESLCRDVPQSLPSFLLTTCGDPDSWIYSDQKCDGVNNCGDCSDELSPVTTCPPCGPGWWRCSPTVFKYCSCVPRDLCRDSVQHCSDWSDEYSCPGP", "length": 218 }, "evidence": [ { "id": "E1BLZ7", "url": "https://omabrowser.org/oma/group/E1BLZ7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4A460-1", "protein_name": "Low density lipoprotein receptor class A domain containing 1", "gene_name": "Ldlrad1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVGAMNKICPQADAESNMTTGRKTRPGGEGCGPLCYSRRGACLSVFLLLLLAMLAALLLIVTILGHPQRTPEPHSCVTLANRTGFLCHDRRYCIPAHAVCDGIRTCPHGEDEAENLCRDLPKSLPSFLLTTCGNPDSWIYSDQKCDGTNNCGDCSDELSPVTACPPCGPGWWYCTPTVFRYCSCVPRVLCRDGVQHCSDWSDEYSCPGP", "length": 210 }, "evidence": [ { "id": "E1BLZ7", "url": "https://omabrowser.org/oma/group/E1BLZ7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5T700-1", "protein_name": "Low-density lipoprotein receptor class A domain-containing protein 1", "gene_name": "LDLRAD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNKVFPQGENGYTAAESKAHPGGEAGGGHLCCSRRGACLSASLLLLLATVAALIALVTILGLPSCTPGAQACITLTNRTGFLCHDQRSCIPASGVCDGVRTCTHGEDEDESLCRDVPQSLPHFLVAHCGDPASWIYSDQKCDGTNNCGDCSDELSPVTVCPPCGPGWWRCPSTFFKYCDCIPRHLCRDHVQHCSDWSDEYACPGP", "length": 205 }, "evidence": [ { "id": "E1BLZ7", "url": "https://omabrowser.org/oma/group/E1BLZ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BLZ7", "url": "https://www.uniprot.org/uniprotkb/E1BLZ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "E1BLZ7", "url": "https://www.uniprot.org/uniprotkb/E1BLZ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BLZ7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 206, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BLZ7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BLZ7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BLZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLZ7" }, { "id": "PF25241", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25241" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LDLRAD1-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 162, "end_pos": 201, "start_aa": "Pro", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 11, "end_pos": 13 }, { "start_pos": 27, "end_pos": 29 }, { "start_pos": 78, "end_pos": 80 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BM04-1", "uniprot_ac": "E1BM04", "uniprot_id": "E1BM04_BOVIN", "mass": { "chemical_mass": 67498.0, "monoisotopic_mass": 67498.0 }, "refseq": {}, "gene_names": [ { "name": "TBKBP1", "type": "recommended", "evidence": [ { "id": "E1BM04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM04" } ] } ], "protein_names": [ { "name": "TBK1 binding protein 1", "type": "synonym", "evidence": [ { "id": "E1BM04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM04/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BM04", "url": "https://www.uniprot.org/uniprotkb/E1BM04" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TBKBP1", "url": "https://www.uniprot.org/uniprotkb/E1BM04", "locus": { "chromosome": "19", "start_pos": 38746990, "end_pos": 38764622, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011280", "url": "https://www.ensembl.org/id/ENSBTAG00000011280" } ] } } ], "crossref": [ { "id": "E1BM04", "url": "https://alphafold.ebi.ac.uk/entry/E1BM04", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011280", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011280", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21965", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21965", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR024581", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024581", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041641", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041641", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051891", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051891", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BM04", "url": "https://www.orthodb.org/?gene=E1BM04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14432", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14432", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14432:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14432:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12845", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12845", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BM04", "url": "https://www.uniprot.org/uniprotkb/E1BM04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM04-1", "url": "https://www.uniprot.org/uniprotkb/E1BM04-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESMFEDDISILTQEALGPSEVWLDAPGDPSLGEDMCSASHFALITAYGDIKERLGGLERENATLRRRLKVYEIKYPLISDFGEEHGFSLYEIKDGSLLEVEKVSLQQRLNQFQHELQKNKEQEEQLGEMIQAYEKLCVEKSDLETELGEMRALVETHLRQICGLEQQLRQQQGLRDVDFPSLSPPPAPAPPCADLDLHYLALRGGSSLSHAGWPGATPSMSELERRRLEEALEAAQGEARGAQLREEQLQAECERLQGELKQLQETRAQDLASNQSERDMAWVKRVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQARSGGQRHSPLSQRHSPAPQCPSHSPPARAAPPCPPCQSPVPQRRSPGPPCPSPQQRRSPASPSCPSPVPQRRSPVPPPCQSPSPQRRSPGPTCPAPQPRPPPPPPPGERTLAERAYAKPPSHHVKAGFQGRRSYSEMAEGAGYAGASPPWLQAEAATLPKPRAYGGELYGPGRPLSPRRAFEGIRLRFEKQPSEEEEWAVPASPPSPEAGAIRCASFCAGFPVPESPAATAYAHAEHAQSWPSINLLMETVGSDILSCPLCQLGFPVGYPDDALIKHIDSHLENSKI", "length": 614, "header": "tr|E1BM04-1|E1BM04_BOVIN Isoform 1 of TBK1 binding protein 1 OS=Bos taurus OX=9913 GN=TBKBP1 PE=4 SV=3 CANONICAL=E1BM04-1" }, "isoforms": [ { "isoform_ac": "E1BM04-1", "url": "https://www.uniprot.org/uniprotkb/E1BM04/entry", "sequence": { "sequence": "MESMFEDDISILTQEALGPSEVWLDAPGDPSLGEDMCSASHFALITAYGDIKERLGGLERENATLRRRLKVYEIKYPLISDFGEEHGFSLYEIKDGSLLEVEKVSLQQRLNQFQHELQKNKEQEEQLGEMIQAYEKLCVEKSDLETELGEMRALVETHLRQICGLEQQLRQQQGLRDVDFPSLSPPPAPAPPCADLDLHYLALRGGSSLSHAGWPGATPSMSELERRRLEEALEAAQGEARGAQLREEQLQAECERLQGELKQLQETRAQDLASNQSERDMAWVKRVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQARSGGQRHSPLSQRHSPAPQCPSHSPPARAAPPCPPCQSPVPQRRSPGPPCPSPQQRRSPASPSCPSPVPQRRSPVPPPCQSPSPQRRSPGPTCPAPQPRPPPPPPPGERTLAERAYAKPPSHHVKAGFQGRRSYSEMAEGAGYAGASPPWLQAEAATLPKPRAYGGELYGPGRPLSPRRAFEGIRLRFEKQPSEEEEWAVPASPPSPEAGAIRCASFCAGFPVPESPAATAYAHAEHAQSWPSINLLMETVGSDILSCPLCQLGFPVGYPDDALIKHIDSHLENSKI", "length": 614, "header": "tr|E1BM04-1|E1BM04_BOVIN Isoform 1 of TBK1 binding protein 1 OS=Bos taurus OX=9913 GN=TBKBP1 PE=4 SV=3 CANONICAL=E1BM04-1" }, "locus": { "chromosome": "19", "start_pos": 38762591, "end_pos": 38748413, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000043249.5", "url": "https://www.ensembl.org/id/ENSBTAT00000043249.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000040836.5", "url": "https://www.ensembl.org/id/ENSBTAP00000040836.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 218, "start_aa": "Thr", "end_pos": 218, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr218", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 419, "start_aa": "Thr", "end_pos": 419, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr419", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BM04", "url": "https://www.uniprot.org/uniprotkb/E1BM04" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BM04", "url": "https://www.uniprot.org/uniprotkb/E1BM04" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BM04-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 614, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BM04-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BM04" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BM04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM04" }, { "id": "PS51905", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51905" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBZ1-type", "eco_id": "ECO_0000259", "start_pos": 582, "end_pos": 608, "start_aa": "Ile", "end_aa": "His", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 218, 419 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 275, "end_pos": 277 }, { "start_pos": 62, "end_pos": 64 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BM11-1", "uniprot_ac": "E1BM11", "uniprot_id": "E1BM11_BOVIN", "mass": { "chemical_mass": 30672.0, "monoisotopic_mass": 30672.0 }, "refseq": { "ac": "NP_001192723", "name": "SLAM family member 8 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192723" }, "gene_names": [ { "name": "SLAMF8", "type": "recommended", "evidence": [ { "id": "E1BM11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM11" } ] }, { "name": "SLAMF8", "type": "synonym", "evidence": [ { "id": "NP_001192723", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192723" } ] } ], "protein_names": [ { "name": "SLAM family member 8 precursor", "type": "synonym", "evidence": [ { "id": "NP_001192723", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192723" } ] }, { "name": "SLAM family member 8", "type": "synonym", "evidence": [ { "id": "E1BM11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM11/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BM11", "url": "https://www.uniprot.org/uniprotkb/E1BM11" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SLAMF8", "url": "https://www.uniprot.org/uniprotkb/E1BM11", "locus": { "chromosome": "3", "start_pos": 9850404, "end_pos": 9860647, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016698", "url": "https://www.ensembl.org/id/ENSBTAG00000016698" } ] } } ], "crossref": [ { "id": "E1BM11", "url": "https://alphafold.ebi.ac.uk/entry/E1BM11", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016698", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016698", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "514609", "url": "https://www.ncbi.nlm.nih.gov/gene/514609", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015631", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015631", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:514609", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514609", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RREGTMD", "url": "https://omabrowser.org/oma/group/RREGTMD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BM11", "url": "https://www.orthodb.org/?gene=E1BM11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12080", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12080", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12080:SF92", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12080:SF92", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001192723", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192723", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BM11", "url": "https://www.uniprot.org/uniprotkb/E1BM11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM11-1", "url": "https://www.uniprot.org/uniprotkb/E1BM11-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVWSLWSLLLWEALLPMVIASAQVQGQVGGSALLVADHPPGFQVREAIWRSLWPSEELLATFFRGSPETLYHSRFLGRAQLHTNLSLELRPLESGDSGNFSVLLVDKQGRARTQTLQLKVYDAVPRPVVKVFIAVSGDAQPPKTCHVFLSCRAPNTSDITYSWRREGTVDLDMEPAGLFTDGQVLSVSLGPGDKGVAYSCIVSNPVSWDLATVTPWESCHRQAAPGRASYKDVLLVVVPVSLLLILAGLSAWHWGPWSGKKKKDVCADEVDQETESPLV", "length": 280, "header": "tr|E1BM11-1|E1BM11_BOVIN Isoform 1 of SLAM family member 8 OS=Bos taurus OX=9913 GN=SLAMF8 PE=4 SV=1 CANONICAL=E1BM11-1" }, "isoforms": [ { "isoform_ac": "E1BM11-1", "url": "https://www.uniprot.org/uniprotkb/E1BM11/entry", "sequence": { "sequence": "MAVWSLWSLLLWEALLPMVIASAQVQGQVGGSALLVADHPPGFQVREAIWRSLWPSEELLATFFRGSPETLYHSRFLGRAQLHTNLSLELRPLESGDSGNFSVLLVDKQGRARTQTLQLKVYDAVPRPVVKVFIAVSGDAQPPKTCHVFLSCRAPNTSDITYSWRREGTVDLDMEPAGLFTDGQVLSVSLGPGDKGVAYSCIVSNPVSWDLATVTPWESCHRQAAPGRASYKDVLLVVVPVSLLLILAGLSAWHWGPWSGKKKKDVCADEVDQETESPLV", "length": 280, "header": "tr|E1BM11-1|E1BM11_BOVIN Isoform 1 of SLAM family member 8 OS=Bos taurus OX=9913 GN=SLAMF8 PE=4 SV=1 CANONICAL=E1BM11-1" }, "locus": { "chromosome": "3", "start_pos": 9860578, "end_pos": 9851064, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022199.5", "url": "https://www.ensembl.org/id/ENSBTAT00000022199.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022199.4", "url": "https://www.ensembl.org/id/ENSBTAP00000022199.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:514609", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514609", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2R3H8-1", "protein_name": "SLAM family member 8", "gene_name": "SLAMF8", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MCWILVVEGAHLPLWSMAVWSLWSLLLCEALFPVVVTSVQVQGQVGGSALLVAERPPGFQVREAIWRCLWPSEELLATFFRDSLETLYHSRFLGRTQLHSNLSLELRPLESGDSGNFSVLLVDKEGRAWTQTLQLKVYDAVPRPVVQVFIAISGDAQPLKTCQVFLSCWAPNISDITYSWRREGTLDLGVEPGELFMDRQLLSVSLGPGDKGVAYSCIVSNPVSWDLATVTPWESCHREAAPGKASYKDALLVVVPVLLLLILAGLSAWCWGPCSGKKKDACADEVAPETENPLVGGP", "length": 298 }, "evidence": [ { "id": "E1BM11", "url": "https://omabrowser.org/oma/group/E1BM11/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZS24-1", "protein_name": "SLAM family member 8", "gene_name": "Slamf8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKEGRSEVTAGLLPIVVISVQVLSKVGDSGLLVAECPPGFQVREAIWRSLWPSEELLATFFRGSLETLYHSRFLGRVQLYDNLSLELGPLRTGDSGNFSVLMVDTGGQTWTQTLHLKVYDAVPKPEVQVFTAATEEAQPLNTCQVFLSCWAPNISDITYSWRREGTMDFNGELRSLFSNGQVLSVSLGLGDKDVAFTCIASNPVSWDMTTVTPWESCHHEAASSGKASYKDVLLVVMPITLFLILAGLFGAWHHGLCSAGKRKDACTDRALPETESAVA", "length": 280 }, "evidence": [ { "id": "E1BM11", "url": "https://omabrowser.org/oma/group/E1BM11/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9P0V8-1", "protein_name": "SLAM family member 8", "gene_name": "SLAMF8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVMRPLWSLLLWEALLPITVTGAQVLSKVGGSVLLVAARPPGFQVREAIWRSLWPSEELLATFFRGSLETLYHSRFLGRAQLHSNLSLELGPLESGDSGNFSVLMVDTRGQPWTQTLQLKVYDAVPRPVVQVFIAVERDAQPSKTCQVFLSCWAPNISEITYSWRRETTMDFGMEPHSLFTDGQVLSISLGPGDRDVAYSCIVSNPVSWDLATVTPWDSCHHEAAPGKASYKDVLLVVVPVSLLLMLVTLFSAWHWCPCSGKKKKDVHADRVGPETENPLVQDLP", "length": 285 }, "evidence": [ { "id": "E1BM11", "url": 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"https://www.uniprot.org/uniprotkb/E1BM11" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BM11-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 280, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BM11-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BM11" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BM11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM11" }, { "id": "PS50835", "database": "PROSITE", "url": 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"evidence": [ { "id": "XP_003587496", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003587496" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BM37", "url": "https://www.uniprot.org/uniprotkb/E1BM37" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CNTD1", "url": "https://www.uniprot.org/uniprotkb/E1BM37", "locus": { "chromosome": "19", "start_pos": 42837827, "end_pos": 42828310, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019912", "url": "https://www.ensembl.org/id/ENSBTAG00000019912" } ] } } ], "crossref": [ { "id": "E1BM37", "url": "https://alphafold.ebi.ac.uk/entry/E1BM37", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000019912", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019912", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20541", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20541", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100847608", "url": "https://www.ncbi.nlm.nih.gov/gene/100847608", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR036915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100847608", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100847608", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR21615", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21615", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21615:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21615:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_003587496", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003587496", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BM37", "url": "https://www.uniprot.org/uniprotkb/E1BM37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM37-1", "url": "https://www.uniprot.org/uniprotkb/E1BM37-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRPERPRLSSLSDFRFGAVATETIEDTLLHLAQQNEQAVQEAAGRMGSFRETRIVEFVFLLSEQWCLEKSVSYQAVEILERFMVKQAENICRQATIQLRGKTEPQNWRALKEQLFNKFILRLVSCVQLASKLSFHYKIISNVTVLNFLRTLGYLHTKEELLESELDVLKSLNFQINLPTPLAYVEMLLEVLGYNGCLVPATQLHATCLILLDLVYLLHEPVYESLLRASIENSTPSQLQGEKFVSVKEDFMLLAVGIIAASAFIQNHECWSQVMGHLQSITGIALESIAEFSYAILTHSVGASTPGQQQPVPPHLVARPPRSALPSTHEAGGICQI", "length": 337, "header": "tr|E1BM37-1|E1BM37_BOVIN Isoform 1 of Cyclin N-terminal domain containing 1 OS=Bos taurus OX=9913 GN=CNTD1 PE=4 SV=4 CANONICAL=E1BM37-1" }, "isoforms": [ { "isoform_ac": "E1BM37-1", "url": "https://www.uniprot.org/uniprotkb/E1BM37/entry", "sequence": { "sequence": "MDRPERPRLSSLSDFRFGAVATETIEDTLLHLAQQNEQAVQEAAGRMGSFRETRIVEFVFLLSEQWCLEKSVSYQAVEILERFMVKQAENICRQATIQLRGKTEPQNWRALKEQLFNKFILRLVSCVQLASKLSFHYKIISNVTVLNFLRTLGYLHTKEELLESELDVLKSLNFQINLPTPLAYVEMLLEVLGYNGCLVPATQLHATCLILLDLVYLLHEPVYESLLRASIENSTPSQLQGEKFVSVKEDFMLLAVGIIAASAFIQNHECWSQVMGHLQSITGIALESIAEFSYAILTHSVGASTPGQQQPVPPHLVARPPRSALPSTHEAGGICQI", "length": 337, "header": "tr|E1BM37-1|E1BM37_BOVIN Isoform 1 of Cyclin N-terminal domain containing 1 OS=Bos taurus OX=9913 GN=CNTD1 PE=4 SV=4 CANONICAL=E1BM37-1" }, "locus": { "chromosome": "19", "start_pos": 42836823, "end_pos": 42828509, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026529.8", "url": "https://www.ensembl.org/id/ENSBTAT00000026529.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026529.7", "url": "https://www.ensembl.org/id/ENSBTAP00000026529.7" } ] } } ], 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"https://www.ebi.ac.uk/QuickGO/term/GO:0007131", "evidence": [ { "database": "UniProtKB", "id": "E1BM37", "url": "https://www.uniprot.org/uniprotkb/E1BM37" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BM37-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 337, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BM37-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BM37" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BM47-1", "uniprot_ac": "E1BM47", "uniprot_id": "E1BM47_BOVIN", "mass": { "chemical_mass": 180805.0, "monoisotopic_mass": 180805.0 }, "refseq": { "ac": "XP_015314563", "name": "maestro heat-like repeat-containing protein family member 2B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015314563" }, "gene_names": [ { "name": "MROH2B", "type": "recommended", "evidence": [ { "id": "E1BM47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM47" } ] }, { "name": "MROH2B", "type": "synonym", "evidence": [ { "id": "XP_015314563", "database": "RefSeq", "url": 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"id": "PTHR23120", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23120", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23120:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23120:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23210", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23210", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23221", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23221", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015314563", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015314563", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MVM1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MVM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MVM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MVM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTY4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTY4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM47", "url": "https://www.uniprot.org/uniprotkb/E1BM47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM47-1", "url": "https://www.uniprot.org/uniprotkb/E1BM47-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEDMDESAEILGDINLTLGMLNKEDNISKEDIYGHLASIIQNTDILDDAIVQRLIYYASKDMRDDNILREIRMLAGEVLVSLAAHDFNSVMYEVQSNFRILELPNEFVVLALAELATSYVSQSIPFMMMTLLTMQTMLRLTEEERMKGAFCVALEKFSRAIYKYVNHWRDFPYPRLDANRLSDKIFMLFRYIMDKWASTTSPTQILAIIKAHGPTVSLLLHREDLCEYALGQVPWLLNQYKDKEIDFHVTQSLRQILTAAVLYDVSLPKALRKAIFINLLRQVCRVPEPPEKENETEASNCFLILAHSNPADLMDFFDEQMRNNNEAIRMGILTLLRSAINAEEPKLRDHVTSIEKAVKVVMGDLSIKVRNSTLLLIQTMCEKCYIEAREGWPLIDYIFTQFSMSNKNLEKPIKPNSQETEKGETSIREISLEVLKTLDPLVIGMPQVLWPRILTFVVPAEYTGTLKYLFNIIRILFMAEERKKKNAKESTALVISTGTVKLPSPQQLLARLLVISMLASVGKLRGAGAIGLLKILPEIIHPNLVELWKTRIPELLQPLEGKNSSIVLWETMLLQLLKESLWKISDVAWTIQLSRDFNQQMDSYSNTSVEKKFLWKALGTTLASCQDVDFVSSQIKEFLAAPHHLGDQRQGITSILGYCAEKHFEVVLKVLKTFQDREKFFMNRCKGIFSGKKSLSKTDVMVIYGAVALHAPKSQLLTRLDQDIVSQVLFLYGQCSRVLGMSVANKDMDLQMSFTRSITEIGIAVQDAEDETFKFSYKEVLLGYMLDFIRDEPLDSLASPIRWKALIAIRYLSKLKPQLSLNDHLNILEENIRRLLPLPPLEKLRNEGETDKDKEHIQFLYERSMDALGKLLRTMMWDNMKAEDCQEMFNLLRMWLVSQKDWERERAFQITAKVLTNDVEAPENFKIGSLLGLLAPHSCDTLPSIRQAAASSAIGLFSIKGVHLEVERLQDLQEGLQCDDVQVQIKISSKIAKIVSKLIPSEEMLVFLEETLDGLESLNPPCTKACGVWMITALKEQGATLEDQLLEILGVIYHHMPVLRQKEESFQFMLEAISQIASFHMDAVVANLLQKPLPFDRDTKTLWKSLAENPASSGKLLRALVDKLENELEDDLARIEAISVACAVYEVVLTGTPVSSLYPELFALLLKLVSCTLGQKMPTSALSRRRRVMPQGERQQIADPCRLSTTTLKCVQAQAMREGLTKESDEGDNVWTLLSSPSTHHIGVCALARSMAVWQHGIIRDITEQLLPSLTSSSENYRITGTAFFSELMKEPVLWKHGNLREVLVLMDQSAWDSNPILRQMAIRGLGNTASGAPHKVKKHKQMMLESVIRGLYHLARTEVVCESLKALKKILDLLTDRDVSFYFKEIVLQTRTFFEDEQDDVRLTAILLFENLASLTGRRWKIFFAEEIKKSMISFLLHLWDPNPKIGTACRDVLIICIPFLGLQELYGVLDHLLDVQDLPRARDFYRQFCMKLSKRNQEILWILHTHSFTFFSSSWETIRSAAIKLTDAIVLNLTYRYVELVDREQLTTQLQALRQDPCISVQRAAEAATQTLLRRCKEISVHL", "length": 1586, "header": "tr|E1BM47-1|E1BM47_BOVIN Isoform 1 of Maestro heat like repeat family member 2B OS=Bos taurus OX=9913 GN=MROH2B PE=4 SV=3 CANONICAL=E1BM47-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MVM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MVM1/entry", "sequence": { "sequence": "MAEDMDESAEILGDINLTLGMLNKEDNISKEDIYGHLASIIQNTDILDDAIVQRLIYYASKDMRDDNILREIRMLAGEVLVSLAAHDFNSVMYEVQSNFRILELPNEFVVLALAELATSYVSQSIPFMMMTLLTMQTMLRLTEEERMKGAFCVALEKFSRAIYKYVNHWRDFPYPRLDANRLSDKIFMLFRYIMDKWASTTSPTQILAIIKAHGPTVSLLLHREDLCEYALGQVPWLLNQYKDKEIDFHVTQSLRQILTAAVLYDVSLPKALRKAIFINLLRQVCRVPEPPEKENETEASNCFLILAHSNPADLMDFFDEQMRNNNEAIRMGILTLLRSAINAEEPKLRDHVTSIEKAVKVVMGDLSIKVRNSTLLLIQTMCEKCYIEAREGWPLIDYIFTQFSMSNKNLEKPIKPNSQETEKGETSIREISLEVLKTLDPLVIGMPQVLWPRILTFVVPAEYTGTLKYLFNIIRILFMAEERKKKNAKESTALVISTGTVKLPSPQQLLARLLVISMLASVGKLRGAGAIGLLKILPEIIHPNLVELWKTRIPELLQPLEGKNSSIVLWETMLLQLLKESLWKISDVAWTIQLSRDFNQQMDSYSNTSVEKKFLWKALGTTLASCQDVDFVSSQIKEFLAAPHHLGDQRQGITSILGYCAEKHFEVVLKVLKTFQDREKFFMNRCKGIFSGKKSLSKTDVMVIYGAVALHAPKSQLLTRLDQDIVSQVLFLYGQCSRVLGMSVANKDMDLQMSFTRSITEIGIAVQDAEDETFKFSYKEVLLGYMLDFIRDEPLDSLASPIRWKALIAIRYLSKLKPQLSLNDHLNILEENIRRLLPLPPLEKLRNEGETDKDKEHIQFLYERSMDALGKLLRTMMWDNMKAEDCQEMFNAPENFKIGSLLGLLAPHSCDTLPSIRQAAASSAIGLFSIKGVHLEVERLQDLQEGLQCDDVQVQIKISSKIAKIVSKLIPSEEMLVFLEETLDGLESLNPPCTKACGVWMITALKEQGATLEDQLLEILGVIYHHMPVLRQKEESFQFMLEAISQIASFHMDAVVANLLQKPLPFDRDTKTLWKSLAENPASSGKLLRALVDKLENELEDDLARIEAISVACAVYEVVLTGTPVSSLYPELFALLLKLVSCTLGQKMPTSALSRRRRVMPQGERQQIADPCRLSTTTLKCVQAQAMREGLTKESDEGDNVWTLLSSPSTHHIGVCALARSMAVWQHGIIRDITEQLLPSLTSSSENYRITGTAFFSELMKEPVLWKHGNLREVLVLMDQSAWDSNPILRQMAIRGLGNTASGAPHKVKKHKQMMLESVIRGLYHLARTEVVCESLKALKKILDLLTDRDVSFYFKEIVLQTRTFFEDEQDDVRLTAILLFENLASLTGRRWKIFFAEEIKKSMISFLLHLWDPNPKIGTACRDVLIICIPFLGLQELYGVLDHLLDVQDLPRARDFYRQFCMKLSKRNQEILWILHTHSFTFFSSSWETIRSAAIKLTDAIVLNLTYRYVELVDREQLTTQLQALRQDPCISVQRAAEAATQTLLRRCKEISVHL", "length": 1556, "header": "tr|A0A3Q1MVM1-1|A0A3Q1MVM1_BOVIN Computationally mapped isoform of Maestro heat like repeat family member 2B OS=Bos taurus OX=9913 GN=MROH2B PE=4 SV=3 CANONICAL=E1BM47-1" }, "locus": { "chromosome": "20", "start_pos": 33514929, "end_pos": 33442058, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075600.3", "url": "https://www.ensembl.org/id/ENSBTAT00000075600.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059128.3", "url": "https://www.ensembl.org/id/ENSBTAP00000059128.3" } ] } }, { "isoform_ac": "A0AAA9TTY4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTY4/entry", "sequence": { "sequence": "MRLKLRRQHFGHLLGRTDSLEKILMLGKIEGRRRGRQRMTGVSIMDSMDMSLSKLRETLKDRCAAVHGVAERRTALSDRTANNSNDPSEDIYGHLASIIQNTDILDDAIVQRLIYYASKDMRDDNILREIRMLAGEVLVSLAAHDFNSVMYEVQSNFRILELPNEFVVLALAELATSYVSQSIPFMMMTLLTMQTMLRLTEEERMKGAFCVALEKFSRAIYKYVNHWRDFPYPRLDANRLSDKIFMLFRYIMDKWASTTSPTQILAIIKAHGPTVSLLLHREDLCEYALGQVPWLLNQYKDKEIDFHVTQSLRQILTAAVLYDVSLPKALRKAIFINLLRQVCRVPEPPEKENETEASNCFLILAHSNPADLMDFFDEQMRNNNEAIRMGILTLLRSAINAEEPKLRDHVTSIEKAVKVVMGDLSIKVRNSTLLLIQTMCEKCYIEAREGWPLIDYIFTQFSMSNKNLEKPIKPNSQETEKGETSIREISLEVLKTLDPLVIGMPQVLWPRILTFVVPAEYTGTLKYLFNIIRILFMAEERKKKNAKESTALVISTGTVKLPSPQQLLARLLVISMLASVGKLRGAGAIGLLKILPEIIHPNLVELWKTRIPELLQPLEGKNSSIVLWETMLLQLLKESLWKISDVAWTIQLSRDFNQQMDSYSNTSVEKKFLWKALGTTLASCQDVDFVSSQIKEFLAAPHHLGDQRQGITSILGYCAEKHFEVVLKVLKTFQDREKFFMNRCKGIFSGKKSLSKTDVMVIYGAVALHAPKSQLLTRLDQDIVSQVLFLYGQCSRVLGMSVANKDMDLQMSFTRSITEIGIAVQDAEDETFKFSYKEVLLGYMLDFIRDEPLDSLASPIRWKALIAIRYLSKLKPQLSLNDHLNILEENIRRLLPLPPLEKLRNEGETDKDKEHIQFLYERSMDALGKLLRTMMWDNMKAEDCQEMFNLLRMWLVSQKDWERERAFQITAKVLTNDVEAPENFKIGSLLGLLAPHSCDTLPSIRQAAASSAIGLFSIKGVHLEVERLQDLQEGLQCDDVQVQIKISSKIAKIVSKLIPSEEMLVFLEETLDGLESLNPPCTKACGVWMITALKEQGATLEDQLLEILGVIYHHMPVLRQKEESFQFMLEAISQIASFHMDAVVANLLQKPLPFDRDTKTLWKSLAENPASSGKLLRALVDKLENELEDDLARIEAISVACAVYEVVLTGTPVSSLYPELFALLLKLVSCTLGQKMPTSALSRRRRVMPQGERQQIADPCRLSTTTLKCVQAQAMREGLTKESDEGDNVWTLLSSPSTHHIGVCALARSMAVWQHGIIRDITEQLLPSLTSSSENYRITGTAFFSELMKEPVLWKHGNLREVLVLMDQSAWDSNPILRQMAIRGLGNTASGAPHKVKKHKQMMLESVIRGLYHLARTEVVCESLKALKKILDLLTDRDVSFYFKEIVLQTRTFFEDEQDDVRLTAILLFENLASLTGRRWKIFFAEEIKKSMISFLLHLWDPNPKIGTACRDVLIICIPFLGLQELYGVLDHLLDVQDLPRARDFYRQFCMKLSKRNQEILWILHTHSFTFFSSSWETIRSAAIKLTDAIVLNLTYRYVELVDREQLTTQLQALRQDPCISVQRAAEAATQTLLRRCKEISVHL", "length": 1644, "header": "tr|A0AAA9TTY4-1|A0AAA9TTY4_BOVIN Computationally mapped isoform of Maestro heat like repeat family member 2B OS=Bos taurus OX=9913 GN=MROH2B PE=4 SV=1 CANONICAL=E1BM47-1" }, "locus": { "chromosome": "20", "start_pos": 33514929, "end_pos": 33443816, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000121118.2", "url": "https://www.ensembl.org/id/ENSBTAT00000121118.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100549.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100549.1" } ] } }, { "isoform_ac": "E1BM47-1", "url": "https://www.uniprot.org/uniprotkb/E1BM47/entry", "sequence": { "sequence": "MAEDMDESAEILGDINLTLGMLNKEDNISKEDIYGHLASIIQNTDILDDAIVQRLIYYASKDMRDDNILREIRMLAGEVLVSLAAHDFNSVMYEVQSNFRILELPNEFVVLALAELATSYVSQSIPFMMMTLLTMQTMLRLTEEERMKGAFCVALEKFSRAIYKYVNHWRDFPYPRLDANRLSDKIFMLFRYIMDKWASTTSPTQILAIIKAHGPTVSLLLHREDLCEYALGQVPWLLNQYKDKEIDFHVTQSLRQILTAAVLYDVSLPKALRKAIFINLLRQVCRVPEPPEKENETEASNCFLILAHSNPADLMDFFDEQMRNNNEAIRMGILTLLRSAINAEEPKLRDHVTSIEKAVKVVMGDLSIKVRNSTLLLIQTMCEKCYIEAREGWPLIDYIFTQFSMSNKNLEKPIKPNSQETEKGETSIREISLEVLKTLDPLVIGMPQVLWPRILTFVVPAEYTGTLKYLFNIIRILFMAEERKKKNAKESTALVISTGTVKLPSPQQLLARLLVISMLASVGKLRGAGAIGLLKILPEIIHPNLVELWKTRIPELLQPLEGKNSSIVLWETMLLQLLKESLWKISDVAWTIQLSRDFNQQMDSYSNTSVEKKFLWKALGTTLASCQDVDFVSSQIKEFLAAPHHLGDQRQGITSILGYCAEKHFEVVLKVLKTFQDREKFFMNRCKGIFSGKKSLSKTDVMVIYGAVALHAPKSQLLTRLDQDIVSQVLFLYGQCSRVLGMSVANKDMDLQMSFTRSITEIGIAVQDAEDETFKFSYKEVLLGYMLDFIRDEPLDSLASPIRWKALIAIRYLSKLKPQLSLNDHLNILEENIRRLLPLPPLEKLRNEGETDKDKEHIQFLYERSMDALGKLLRTMMWDNMKAEDCQEMFNLLRMWLVSQKDWERERAFQITAKVLTNDVEAPENFKIGSLLGLLAPHSCDTLPSIRQAAASSAIGLFSIKGVHLEVERLQDLQEGLQCDDVQVQIKISSKIAKIVSKLIPSEEMLVFLEETLDGLESLNPPCTKACGVWMITALKEQGATLEDQLLEILGVIYHHMPVLRQKEESFQFMLEAISQIASFHMDAVVANLLQKPLPFDRDTKTLWKSLAENPASSGKLLRALVDKLENELEDDLARIEAISVACAVYEVVLTGTPVSSLYPELFALLLKLVSCTLGQKMPTSALSRRRRVMPQGERQQIADPCRLSTTTLKCVQAQAMREGLTKESDEGDNVWTLLSSPSTHHIGVCALARSMAVWQHGIIRDITEQLLPSLTSSSENYRITGTAFFSELMKEPVLWKHGNLREVLVLMDQSAWDSNPILRQMAIRGLGNTASGAPHKVKKHKQMMLESVIRGLYHLARTEVVCESLKALKKILDLLTDRDVSFYFKEIVLQTRTFFEDEQDDVRLTAILLFENLASLTGRRWKIFFAEEIKKSMISFLLHLWDPNPKIGTACRDVLIICIPFLGLQELYGVLDHLLDVQDLPRARDFYRQFCMKLSKRNQEILWILHTHSFTFFSSSWETIRSAAIKLTDAIVLNLTYRYVELVDREQLTTQLQALRQDPCISVQRAAEAATQTLLRRCKEISVHL", "length": 1586, "header": "tr|E1BM47-1|E1BM47_BOVIN Isoform 1 of Maestro heat like repeat family member 2B OS=Bos taurus OX=9913 GN=MROH2B PE=4 SV=3 CANONICAL=E1BM47-1" }, "locus": { "chromosome": "20", "start_pos": 33514929, "end_pos": 33442058, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002589.6", "url": "https://www.ensembl.org/id/ENSBTAT00000002589.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002589.5", "url": "https://www.ensembl.org/id/ENSBTAP00000002589.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:518808", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:518808", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BM47", "url": "https://www.uniprot.org/uniprotkb/E1BM47" } ], "pmid": "" }, { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "E1BM47", "url": "https://www.uniprot.org/uniprotkb/E1BM47" } ], "pmid": "" }, { "name": "sperm midpiece", "id": "GO:0097225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097225", "evidence": [ { "database": "UniProtKB", "id": "E1BM47", "url": "https://www.uniprot.org/uniprotkb/E1BM47" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling adaptor activity", "id": "GO:0035591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035591", "evidence": [ { "database": "UniProtKB", "id": "E1BM47", "url": "https://www.uniprot.org/uniprotkb/E1BM47" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cAMP/PKA signal transduction", "id": "GO:0141156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141156", "evidence": [ { "database": "UniProtKB", "id": "E1BM47", "url": "https://www.uniprot.org/uniprotkb/E1BM47" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1535, "end_pos": 1537, "annotation": "n_glycosylation_sequon" }, { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" }, { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" }, { "start_pos": 295, "end_pos": 297, "annotation": "n_glycosylation_sequon" }, { "start_pos": 372, "end_pos": 374, "annotation": "n_glycosylation_sequon" }, { "start_pos": 564, "end_pos": 566, "annotation": "n_glycosylation_sequon" }, { "start_pos": 607, "end_pos": 609, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BM47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM47" }, { "id": "PF23210", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23210" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MROH2B-like HEAT-repeats", "eco_id": "ECO_0000259", "start_pos": 221, "end_pos": 879, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": [] }, { "evidence": [ { "id": "E1BM47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM47" }, { "id": "PF23221", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23221" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MROH2B-like N-terminal HEAT-repeats", "eco_id": "ECO_0000259", "start_pos": 19, "end_pos": 216, "start_aa": "Leu", "end_aa": "Thr", "glycosite_overlap": [] }, { "evidence": [ { "id": "E1BM47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM47" }, { "id": "PF21047", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21047" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Maestro-like HEAT-repeats", "eco_id": "ECO_0000259", "start_pos": 903, "end_pos": 1118, "start_aa": "Trp", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "E1BM47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM47" }, { "id": "PF23227", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23227" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Maestro/Maestro-like HEAT-repeats", "eco_id": "ECO_0000259", "start_pos": 1305, "end_pos": 1575, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1535, "end_pos": 1537 }, { "start_pos": 16, "end_pos": 18 }, { "start_pos": 27, "end_pos": 29 }, { "start_pos": 295, "end_pos": 297 }, { "start_pos": 372, "end_pos": 374 }, { "start_pos": 564, "end_pos": 566 }, { "start_pos": 607, "end_pos": 609 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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"MLTTLWLLLCFALPVHESPFPISCPNHKHCQLALLSNNDIILHCNAPGAQWQFLTPLKTTWANNSTTNLNMVTMLNGNLLIKNPLPSHTGIYNCNDKDGKKVMRYEIDFQDVVTLHITHKDLDQKPLQNESLSLSSKQFVFTHWEPWQDCNRCGEPGERKRLGYCYIQESLENPMPCWLYLGDEKLWSSRLRPEMQVETCHIPCSAKYVIFDNFQLRNKVGSAWLTCPLGSIYRPVLWEANNLSLTWKDQLSGKSISTIMDSSNGGSWLQVFQSAIYRCFVQQELMAQFNSKVSVDPLKFLVPEKSKQQPEAEKTRKENANSVLKGLNVMMLVGTVLTVLGCLFKQFRFSQSRKRNKMFLVK", "length": 362, "header": "tr|E1BM49-1|E1BM49_BOVIN Isoform 1 of Family with sequence similarity 187 member B OS=Bos taurus OX=9913 GN=FAM187B PE=4 SV=3 CANONICAL=E1BM49-1" }, "locus": { "chromosome": "18", "start_pos": 45941600, "end_pos": 45936353, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002585.7", "url": "https://www.ensembl.org/id/ENSBTAT00000002585.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002585.7", "url": "https://www.ensembl.org/id/ENSBTAP00000002585.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], 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} ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BM64-1", "uniprot_ac": "E1BM64", "uniprot_id": "E1BM64_BOVIN", "mass": { "chemical_mass": 108414.0, "monoisotopic_mass": 108414.0 }, "refseq": { "ac": "NP_001193035", "name": "dystrophin-related protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193035" }, "gene_names": [ { "name": "DRP2", "type": "recommended", "evidence": [ { "id": "E1BM64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM64" } ] }, { "name": "DRP2", "type": "synonym", "evidence": [ { "id": "NP_001193035", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193035" } ] } ], "protein_names": [ { "name": "Dystrophin related protein 2", "type": "synonym", "evidence": [ { "id": "E1BM64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM64/entry#names_and_taxonomy" } ] 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"MQPMVMQGCPYTLPRCHKWREADNFHHSRSLRSTCPQPQVRAAAATPAPPHNGAGVPCLSPKLFNGSVVAARTLEPPAMNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVVLVQQEKETHAAFMEDVKSRGPYIYSVLESAQAFLSQHPFDELEEPRSESKDTSPRQRIQNLSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELNATLTQAEGVRATWEPIGDLFIDSLPEHIQALKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMENSRALEQINIRWKQLQVSVGERLKQLQDAHRDFGPGSQHFLSSSVQVPWERAISPNKVPYYINHQAQTTCWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQASEHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKTGIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEPSVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTIAEQVKHQTKCSICRQCPIKGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFRSKHYFSKHPQRGYLPVQSVLEADYNETPASSPMLPHADTHSRIEHFASRLAEMESQNCSFFNDSLSPDDSIDEDQYLLRHSSPVTDREPAFRQQAPHNMATGSKGELEKILAHLEDENRILQGELRRLKWQHEEATEVPALTEGSAEVAQGHCNEELLAEARILRQHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPIESNGNGSAGSSLASSPQQSEGSHPQEKGQTTPDTEAADDVGLKSQDVSLCLEDIMEKLRHAFPSVRSSDVTANTLLAS", "length": 957, "header": "tr|E1BM64-1|E1BM64_BOVIN Isoform 1 of Dystrophin related protein 2 OS=Bos taurus OX=9913 GN=DRP2 PE=4 SV=3 CANONICAL=E1BM64-1" }, "isoforms": [ { "isoform_ac": "E1BM64-1", "url": "https://www.uniprot.org/uniprotkb/E1BM64/entry", "sequence": { "sequence": "MQPMVMQGCPYTLPRCHKWREADNFHHSRSLRSTCPQPQVRAAAATPAPPHNGAGVPCLSPKLFNGSVVAARTLEPPAMNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVVLVQQEKETHAAFMEDVKSRGPYIYSVLESAQAFLSQHPFDELEEPRSESKDTSPRQRIQNLSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELNATLTQAEGVRATWEPIGDLFIDSLPEHIQALKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMENSRALEQINIRWKQLQVSVGERLKQLQDAHRDFGPGSQHFLSSSVQVPWERAISPNKVPYYINHQAQTTCWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQASEHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKTGIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEPSVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTIAEQVKHQTKCSICRQCPIKGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFRSKHYFSKHPQRGYLPVQSVLEADYNETPASSPMLPHADTHSRIEHFASRLAEMESQNCSFFNDSLSPDDSIDEDQYLLRHSSPVTDREPAFRQQAPHNMATGSKGELEKILAHLEDENRILQGELRRLKWQHEEATEVPALTEGSAEVAQGHCNEELLAEARILRQHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPIESNGNGSAGSSLASSPQQSEGSHPQEKGQTTPDTEAADDVGLKSQDVSLCLEDIMEKLRHAFPSVRSSDVTANTLLAS", "length": 957, "header": "tr|E1BM64-1|E1BM64_BOVIN Isoform 1 of Dystrophin related protein 2 OS=Bos taurus OX=9913 GN=DRP2 PE=4 SV=3 CANONICAL=E1BM64-1" }, "locus": { "chromosome": "X", "start_pos": 50942397, "end_pos": 50913544, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002564.7", "url": "https://www.ensembl.org/id/ENSBTAT00000002564.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002564.6", "url": "https://www.ensembl.org/id/ENSBTAP00000002564.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 46, "start_aa": "Thr", "end_pos": 46, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr46", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:537422", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:537422", "resource": "KEGG Pathway" }, { "id": "R-BTA-9913351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9913351", "resource": "Reactome", "description": "Formation of the dystrophin-glycoprotein complex (DGC)" } ], "orthologs": [ { "uniprot_canonical_ac": "Q05AA6-1", "protein_name": "Dystrophin-related protein 2", "gene_name": "Drp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQPLVMQGCPYTLPRCHEWHAADRFHHSSSLRNTCPQPQVRAAVTIPAPPWDGAGDPCLSPKLLNGTVGATGPLEPSAMNLCWNEIKKKSHNLRARLEAFSDLSGKLQLPLREIIDWLSQKDEELSAQLPLQGDVALVQQEKETHAAFMEEVKSKGPYISSVLESAQAFLSQHPFEELEESQSESKDTSPRQRIQNLSRFVWKQATVASELWEKLTARCVDQHRHIEHTLEHLLEIQGAMEELSSTLTQAEGVRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPVKDGVKLVNDLAHQLAISDVHLSMENSRALEQINIRWKQLQVSVAERLKQLQDAHRDFGPGSQHFLSTSVQVPWERAISPNKVPYYINHQAQTTCWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQASEHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKTGIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGALLHEAIQVPRQLGEVAAFGGSNVEPSVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTIAEQVKHQTKCSICRQCPIKGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFRSKQYFSKHPQRGYLPVQSVLESDCSETPASSPMLPHADTHSRIEHFASRLAEMESQNCSFFNDSLSPDDSIDEDQYLLRHSSPITDREPAFGQQAPCSMATESKGELEKILAHLEDENRILQGELRRLKWQHEEAAEAPTLVEGSAEATPDHRNEELLAEARILRQHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPSESDGNGSAGSSLASSPRQSEGSHPREKGQTTPDTEVADDVGSKSQDVSLCLEDIMEKLRHAFPSVRSSDVTANTLLAS", "length": 957 }, "evidence": [ { "id": "E1BM64", "url": "https://omabrowser.org/oma/group/E1BM64/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q13474-1", "protein_name": "Dystrophin-related protein 2", "gene_name": "DRP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQPMVMQGCPYTLPRCHDWQAADQFHHSSSLRSTCPHPQVRAAVTSPAPPQDGAGVPCLSLKLLNGSVGASGPLEPPAMNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNLSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMENSQALEQINVRWKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQVPWERAISPNKVPYYINHQAQTTCWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQASEHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKTGIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEPSVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTIAEQVKHQTKCSICRQCPIKGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFRSKHYFSKHPQRGYLPVQSVLEADYSETPASSPMWPHADTHSRIEHFASRLAEMESQNCSFFNDSLSPDDSIDEDQYLLRHSSPITDREPAFGQQAPCSVATESKGELQKILAHLEDENRILQGELRRLKWQHEEAAEAPSLADGSTEAATDHRNEELLAEARILRQHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPTESDGSGSAGSSLASSPQQSEGSHPREKGQTTPDTEAADDVGSKSQDVSLCLEDIMEKLRHAFPSVRSSDVTANTLLAS", "length": 957 }, "evidence": [ { "id": "E1BM64", "url": "https://omabrowser.org/oma/group/E1BM64/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9EPA0-1", "protein_name": "Dystrophin-related protein 2", "gene_name": "Drp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQPLVMQGCPYTLPRCHEWHAADRFHHSSSLRNTCPQPQVRAAVTIPAPPWDGAGDPCLSPKLLNGSVGAVGPLEPSAMNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALVQQEKETHAAFMEEVKSKGPYIYSVLESAQAFLSQHPFEELEESHSESKDTSPRQRIQNLSRFVWKQATVASELWEKLTARCVDQHRHIEHTLEHLLEIQGAMEELSSTLTQAEGVRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPVKDGVKLVNDLAHQLAISDVHLSMENSRALEQINVRWKQLQVSVAERLKQLQDAHRDFGPGSQHFLSTSVQVPWERAISPNKVPYYINHQAQTTCWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQASEHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKTGIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGALLHEAIQVPRQLGEVAAFGGSNVEPSVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTVAEQVKHQTKCSICRQCPIKGFRYRSLKQFNVDICQTCFLTGKASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFRSKQYFSKHPQRGYLPVQSVLESDCSETPASSPMLPHADTHSRIEHFASRLAEMESQNCSFFNDSLSPDDSIDEDQYLLRHSSPITDREPAFGQQAPCSMATESKGELEKILAHLEDENRILQGELRRLKWQHEEAVEAPTLAEGSAEATPDHRNEELLAEARILRQHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPTESDGNGSAGSSLASSPRQSEGSHPREKGQTTPDTEAADDVGSKSQDVSLCLEDIMEKLRHAFPSVRSSDVTANTLLAS", "length": 957 }, "evidence": [ { "id": "E1BM64", "url": "https://omabrowser.org/oma/group/E1BM64/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BM64", "url": "https://www.uniprot.org/uniprotkb/E1BM64" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "E1BM64", "url": "https://www.uniprot.org/uniprotkb/E1BM64" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BM64", "url": "https://www.uniprot.org/uniprotkb/E1BM64" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "synaptic signaling", "id": "GO:0099536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099536", "evidence": [ { "database": "UniProtKB", "id": "E1BM64", "url": "https://www.uniprot.org/uniprotkb/E1BM64" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" }, { "start_pos": 703, "end_pos": 705, "annotation": "n_glycosylation_sequon" }, { "start_pos": 735, "end_pos": 737, "annotation": "n_glycosylation_sequon" }, { "start_pos": 740, "end_pos": 742, "annotation": "n_glycosylation_sequon" }, { "start_pos": 884, "end_pos": 886, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BM64-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 957, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BM64-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BM64" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BM64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM64" }, { "id": "PS50020", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50020" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WW", "eco_id": "ECO_0000259", "start_pos": 352, "end_pos": 385, "start_aa": "Ser", "end_aa": "Met", "glycosite_overlap": [] }, { "evidence": [ { "id": "E1BM64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM64" }, { "id": "PS50135", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50135" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ZZ-type", "eco_id": "ECO_0000259", "start_pos": 605, "end_pos": 661, "start_aa": "Lys", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 46 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 196, "end_pos": 198 }, { "start_pos": 244, "end_pos": 246 }, { "start_pos": 65, "end_pos": 67 }, { "start_pos": 703, "end_pos": 705 }, { "start_pos": 735, "end_pos": 737 }, { "start_pos": 740, "end_pos": 742 }, { "start_pos": 884, "end_pos": 886 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BM85-1", "uniprot_ac": "E1BM85", "uniprot_id": "E1BM85_BOVIN", "mass": { "chemical_mass": 83788.0, "monoisotopic_mass": 83788.0 }, "refseq": { "ac": "XP_010807351", "name": "immunoglobulin superfamily DCC subclass member 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010807351" }, "gene_names": [ { "name": "IGDCC3", "type": "recommended", "evidence": [ { "id": "E1BM85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM85" } ] }, { "name": "IGDCC3", "type": "synonym", "evidence": [ { "id": "XP_010807351", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010807351" } ] } ], "protein_names": [ { "name": "Immunoglobulin superfamily DCC subclass member 3", "type": "recommended", "evidence": [ { "id": "E1BM85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM85/entry#names_and_taxonomy" } ] }, { "name": "Putative neuronal cell adhesion molecule", "type": "synonym", "evidence": [ { "id": "E1BM85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM85/entry#names_and_taxonomy" } ] }, { "name": "immunoglobulin superfamily DCC subclass member 3", "type": "synonym", "evidence": [ { "id": "XP_010807351", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010807351" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BM85", "url": "https://www.uniprot.org/uniprotkb/E1BM85" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "IGDCC3", "url": "https://www.uniprot.org/uniprotkb/E1BM85", "locus": { "chromosome": "10", "start_pos": 12269523, "end_pos": 12311904, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008828", "url": "https://www.ensembl.org/id/ENSBTAG00000008828" } ] } } ], "crossref": [ { "id": "E1BM85", "url": "https://alphafold.ebi.ac.uk/entry/E1BM85", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008828", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008828", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "529830", "url": "https://www.ncbi.nlm.nih.gov/gene/529830", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:529830", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:529830", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BM85", "url": "https://www.orthodb.org/?gene=E1BM85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44170", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44170", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44170:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44170:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010807351", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010807351", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BM85", "url": "https://www.uniprot.org/uniprotkb/E1BM85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM85-1", "url": "https://www.uniprot.org/uniprotkb/E1BM85-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASRAAPPRRRPRLLLPLLPLLLLPAPSDGLGHSAELAFAVEPSDDIAVPGQPVMLGCKVEGIPPVRITWRKNGVELADSTHSTVLANGSLMIRHFLLDGGGSPSDEGDYECVAQNRFGLVVSRKARIQAATMSDFHVHPQATVGEEGGVARFQCQIHGLPKPLITWEKNRVPIDTDNERYTLLPKGVLQITGLRAEDSGVFHCVASNIASVRVSHGARLTVTGSGSGAYKEPTILVGPENLTLTVHQTAVLECVATGNPRPIVSWSRLDGRPIGVEGIQVLGTGNLIISDVTVQHSGVYVCAANRPGTRVRRTAQGRLVVQAPAEFVQHPQSISRPVGTTAMFTCQAQGEPPPHVTWLKNGRVLGPGGHVRLKNNNSTLTISGIGPEDEAIYQCVAENSAGSSQASARLTVLWAEGLPGPPLNVQAVSVSSTEVRVSWTEPLVNTREIIGYVLHIRKAADPPELEYQEAVSKSTFQHLVSDLEPSTAYSFYIKAYTPRGASSASAPTLVSTLGEAPAPPPLSVRVLGSSTLQLLWEPWPRLAQHEGGFKLFYRPASKASFTGPILLPGAVSSYNLSQLDPTAVYEVKLLAYNQHGDGNATVRFVSLRGAAERTALSPPCDCRKEEATNQTSTTGIVIGIHIGVTCIIFCVLFLLFGQRGRVLLCKDVENQLSPPQGPRSQRDPGILALNGAGRAERAQLGRDGKRVDVKELEQLFPRAGAVQPHPRPTDPEAPALCEETQLSMLPLQGFSLLEEMPLEALPPQDVGPGLLSEGPAAQPAPSGP", "length": 785, "header": "tr|E1BM85-1|E1BM85_BOVIN Isoform 1 of Immunoglobulin superfamily DCC subclass member 3 OS=Bos taurus OX=9913 GN=IGDCC3 PE=3 SV=4 CANONICAL=E1BM85-1" }, "isoforms": [ { "isoform_ac": "E1BM85-1", "url": "https://www.uniprot.org/uniprotkb/E1BM85/entry", "sequence": { "sequence": "MAASRAAPPRRRPRLLLPLLPLLLLPAPSDGLGHSAELAFAVEPSDDIAVPGQPVMLGCKVEGIPPVRITWRKNGVELADSTHSTVLANGSLMIRHFLLDGGGSPSDEGDYECVAQNRFGLVVSRKARIQAATMSDFHVHPQATVGEEGGVARFQCQIHGLPKPLITWEKNRVPIDTDNERYTLLPKGVLQITGLRAEDSGVFHCVASNIASVRVSHGARLTVTGSGSGAYKEPTILVGPENLTLTVHQTAVLECVATGNPRPIVSWSRLDGRPIGVEGIQVLGTGNLIISDVTVQHSGVYVCAANRPGTRVRRTAQGRLVVQAPAEFVQHPQSISRPVGTTAMFTCQAQGEPPPHVTWLKNGRVLGPGGHVRLKNNNSTLTISGIGPEDEAIYQCVAENSAGSSQASARLTVLWAEGLPGPPLNVQAVSVSSTEVRVSWTEPLVNTREIIGYVLHIRKAADPPELEYQEAVSKSTFQHLVSDLEPSTAYSFYIKAYTPRGASSASAPTLVSTLGEAPAPPPLSVRVLGSSTLQLLWEPWPRLAQHEGGFKLFYRPASKASFTGPILLPGAVSSYNLSQLDPTAVYEVKLLAYNQHGDGNATVRFVSLRGAAERTALSPPCDCRKEEATNQTSTTGIVIGIHIGVTCIIFCVLFLLFGQRGRVLLCKDVENQLSPPQGPRSQRDPGILALNGAGRAERAQLGRDGKRVDVKELEQLFPRAGAVQPHPRPTDPEAPALCEETQLSMLPLQGFSLLEEMPLEALPPQDVGPGLLSEGPAAQPAPSGP", "length": 785, "header": "tr|E1BM85-1|E1BM85_BOVIN Isoform 1 of Immunoglobulin superfamily DCC subclass member 3 OS=Bos taurus OX=9913 GN=IGDCC3 PE=3 SV=4 CANONICAL=E1BM85-1" }, "locus": { "chromosome": "10", "start_pos": 12311903, "end_pos": 12270527, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000048688.4", "url": "https://www.ensembl.org/id/ENSBTAT00000048688.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000045681.4", "url": "https://www.ensembl.org/id/ENSBTAP00000045681.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:529830", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:529830", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BM85", "url": "https://www.uniprot.org/uniprotkb/E1BM85" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "E1BM85", "url": "https://www.uniprot.org/uniprotkb/E1BM85" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 377, "end_pos": 379, "annotation": "n_glycosylation_sequon" }, { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" }, { "start_pos": 576, "end_pos": 578, "annotation": "n_glycosylation_sequon" }, { "start_pos": 600, "end_pos": 602, "annotation": "n_glycosylation_sequon" }, { "start_pos": 630, "end_pos": 632, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BM85-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 785, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BM85-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BM85" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BM85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM85" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 422, "end_pos": 516, "start_aa": "Pro", "end_aa": "Glu", "glycosite_overlap": [] }, { "evidence": [ { "id": "E1BM85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM85" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 21, "end_pos": 135, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 242, "end_pos": 244 }, { "start_pos": 377, "end_pos": 379 }, { "start_pos": 378, "end_pos": 380 }, { "start_pos": 576, "end_pos": 578 }, { "start_pos": 600, "end_pos": 602 }, { "start_pos": 630, "end_pos": 632 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BM88-1", "uniprot_ac": "E1BM88", "uniprot_id": "E1BM88_BOVIN", "mass": { "chemical_mass": 57778.0, "monoisotopic_mass": 57778.0 }, "refseq": { "ac": "NP_001422079", "name": "T-cell activation inhibitor, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422079" }, "gene_names": [ { "name": "TCAIM", "type": "recommended", "evidence": [ { "id": "E1BM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM88" } ] }, { "name": "C22H3orf23", "type": "synonym", "evidence": [ { "id": "NP_001422079", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422079" } ] }, { "name": "TCAIM", "type": "synonym", "evidence": [ { "id": "NP_001422079", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422079" } ] } ], "protein_names": [ { "name": "T cell activation inhibitor, mitochondrial", "type": "synonym", "evidence": [ { "id": "E1BM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM88/entry#names_and_taxonomy" } ] }, { "name": "T-cell activation inhibitor, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001422079", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422079" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BM88", "url": "https://www.uniprot.org/uniprotkb/E1BM88" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TCAIM", "url": "https://www.uniprot.org/uniprotkb/E1BM88", "locus": { "chromosome": "22", "start_pos": 16309668, "end_pos": 16271889, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016622", "url": "https://www.ensembl.org/id/ENSBTAG00000016622" } ] } } ], "crossref": [ { "id": "E1BM88", "url": "https://alphafold.ebi.ac.uk/entry/E1BM88", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016622", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016622", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "515010", "url": "https://www.ncbi.nlm.nih.gov/gene/515010", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027986", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027986", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028031", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028031", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KLHISHY", "url": "https://omabrowser.org/oma/group/KLHISHY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BM88", "url": "https://www.orthodb.org/?gene=E1BM88", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31596", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31596", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31596:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31596:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14687", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14687", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14688", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14688", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001422079", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422079", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SNF4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SNF4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNF4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM88", "url": "https://www.uniprot.org/uniprotkb/E1BM88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM88-1", "url": "https://www.uniprot.org/uniprotkb/E1BM88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MIL8", "url": "https://www.uniprot.org/uniprotkb/F1MIL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MIL8-1", "url": "https://www.uniprot.org/uniprotkb/F1MIL8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFCHLRPVRRLCPGKILPYCFLLSRALSGAEAVNALRPFYFAVHPDFFGQHPREREVNENSLKRLSAYLENLQKPGFKSLKPTQLVFYVRETDQNPSDGQEHFSTSGFRAVKFTLHTRDLLSTVLYILNSCSLSIEHVQSLNTNVHSQPLKEAKRTSDRPIKWDKSYYSFTGFKDPDEDLEQVWRTETTLTSWLDNNGESAVKKLKNSLPLRQELDRLKDELSHQLQLSDIRWQRSWGIAHRCSQLHSLGRLAQQNLETLKNAKGCTIIFTDRSGMSAVGHVMLGTMDVHHHWTKLFERLPSYFDLQRRLTHLEDQISYLLGGIQVVYIEELQPVLTLEEYYSLLDVFYNRLLKSRIPFHPRSLRGLQMILNSDRYAPSLHELGHFNIPVLCDPANLQWFILTKAQQARENMKKREELKVIENELMQASTKKFCLEKFYKEPSVSSIQMVDCCKRLLEQSLPYLQGMHLCISHFYSVMQDGDLCIPWNWKNGEAIK", "length": 496, "header": "tr|E1BM88-1|E1BM88_BOVIN Isoform 1 of T cell activation inhibitor, mitochondrial OS=Bos taurus OX=9913 GN=TCAIM PE=4 SV=1 CANONICAL=E1BM88-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SNF4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNF4/entry", "sequence": { "sequence": "MFCHLRPVRRLCPGKILPYCFLLSRALSGAEAVNALRPFYFAVHPDFFGQHPRERVDIRKVFQWLNS", "length": 67, "header": "tr|A0AAA9SNF4-1|A0AAA9SNF4_BOVIN Computationally mapped isoform of T cell activation inhibitor, mitochondrial OS=Bos taurus OX=9913 GN=TCAIM PE=4 SV=1 CANONICAL=E1BM88-1" }, "locus": { "chromosome": "22", "start_pos": 16286866, "end_pos": 16280834, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000088757.2", "url": "https://www.ensembl.org/id/ENSBTAT00000088757.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087853.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087853.1" } ] } }, { "isoform_ac": "E1BM88-1", "url": "https://www.uniprot.org/uniprotkb/E1BM88/entry", "sequence": { "sequence": "MFCHLRPVRRLCPGKILPYCFLLSRALSGAEAVNALRPFYFAVHPDFFGQHPREREVNENSLKRLSAYLENLQKPGFKSLKPTQLVFYVRETDQNPSDGQEHFSTSGFRAVKFTLHTRDLLSTVLYILNSCSLSIEHVQSLNTNVHSQPLKEAKRTSDRPIKWDKSYYSFTGFKDPDEDLEQVWRTETTLTSWLDNNGESAVKKLKNSLPLRQELDRLKDELSHQLQLSDIRWQRSWGIAHRCSQLHSLGRLAQQNLETLKNAKGCTIIFTDRSGMSAVGHVMLGTMDVHHHWTKLFERLPSYFDLQRRLTHLEDQISYLLGGIQVVYIEELQPVLTLEEYYSLLDVFYNRLLKSRIPFHPRSLRGLQMILNSDRYAPSLHELGHFNIPVLCDPANLQWFILTKAQQARENMKKREELKVIENELMQASTKKFCLEKFYKEPSVSSIQMVDCCKRLLEQSLPYLQGMHLCISHFYSVMQDGDLCIPWNWKNGEAIK", "length": 496, "header": "tr|E1BM88-1|E1BM88_BOVIN Isoform 1 of T cell activation inhibitor, mitochondrial OS=Bos taurus OX=9913 GN=TCAIM PE=4 SV=1 CANONICAL=E1BM88-1" }, "locus": { "chromosome": "22", "start_pos": 16307973, "end_pos": 16280834, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022111.7", "url": "https://www.ensembl.org/id/ENSBTAT00000022111.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022111.4", "url": "https://www.ensembl.org/id/ENSBTAP00000022111.4" } ] } }, { "isoform_ac": "F1MIL8-1", "url": "https://www.uniprot.org/uniprotkb/F1MIL8/entry", "sequence": { "sequence": "MFCHLRPVRRLCPGKILPYCFLLSRALSGAEAVNALRPFYFAVHPDFFGQHPREREVNENSLKRLSAYLENLQKPGFKSLKPTQLVFYVRETDQNPSDGQEHFSTSGFRAVKFTLHTRDLLSTVLYILNSCSLSIEHVQSLNTNVHSQPLKEAKRTSDRPIKWDKSYYSFTGFKDPDEDLEQVWRTETTLTSWLDNNGESAVKKLKNSLPLRQELDRLKDELSHQLQLSDIRWQRSWGIAHRCSQLHSLGRLAQQNLETLKNAKAF", "length": 266, "header": "tr|F1MIL8-1|F1MIL8_BOVIN Computationally mapped isoform of T cell activation inhibitor, mitochondrial OS=Bos taurus OX=9913 GN=TCAIM PE=4 SV=1 CANONICAL=E1BM88-1" }, "locus": { "chromosome": "22", "start_pos": 16302838, "end_pos": 16280834, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000047486.3", "url": "https://www.ensembl.org/id/ENSBTAT00000047486.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000044691.2", "url": "https://www.ensembl.org/id/ENSBTAP00000044691.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287ADZ0-1", "protein_name": "T cell activation inhibitor, mitochondrial", "gene_name": "TCAIM", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFCHLRPMRRLCLGKIFPYWFLCSRALSGAEAVNALRPFYFAVHPDFFGQHPREREVNENSLKRLSAYLENLQKPGSKSLKPTQLMFYVRETDQNSSEGQEHFTTSGFRAVKFTLHTRDLLSTVLYILNSCSLSVEHIQSSNTNVHSQPLKKAQRMSDRPIKWDKSYYSFTGFKDPDEDLEQVWRMETTLTSWLDNNGKSAVKKLKNSLPLRKELSRLKDELSHQLELSDIRWQRSWGIAHRCSQLHSLGRLAQQNLETLKNAKGCTIIFTDRSGMSAVGHVMLGTMDVHHHWTKLFERLPSYFDLQRRLMLLEDQISYLLGGIQVVYIEELQPVLTLEEYYSLLDVFYNRLSKSRIPFHPRSLRGLQMILNSDRYAPSLHELGHFNIPTLCDLANLQWFILTKAQQARENMKRKEELKVMEHELMQASTKKFSLEKFYKEPSVSSMQMVDCCQRLLEQSLPYLQGMHLCVSHFYSVMQDGDLAFLGIGRVEKPLNNTEICIPF", "length": 504 }, "evidence": [ { "id": "E1BM88", "url": "https://omabrowser.org/oma/group/E1BM88/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P0DKR2-1", "protein_name": "T-cell activation inhibitor, mitochondrial", "gene_name": "Tcaim", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLGSWRAFSEMFCHLRPWRRFCLRKVLPPWLHYSRALSGAEAINALRPFYFAVHPDFFGQHPREREVNENSLKRLSVYLENLQKPGFKSLKPTQLTFYIREKTAQNSSEGQEPVSTTGFRAVRFTLHSSDLLSTVLYILNSCSLPVEHVQSLNTNVHSQPLKEATGMPDRPIKWHRSYYSFTGFKDPDEDLEHVSRVETTLTSWLGSNGKGAVKKLKNSLPLRKELDRLKNELSELLQLSDIRWQRGWGVAHRCSQLHSLSRLAQQNLEPLQNAKGCTIVFTDRSGMSALGHVMLGTMDVHHHWTRLFESLPNYFDLQRRMSALEDQISHLLGGIQVVYIEELQPALTLDEYYSLLDTFYNQLQRSRAPPRPQSLSGLQMILSRYAPSLHELGHFNIPALSDPASLQSFMRTKAQQARENMRRREKLKVIENELIQASTRKFSLEKLYKEPSISSRQMVDCCKRLLEQSLPYLHGMHLCVSHFYSVMQDGDLCIPWNWKKGEAMK", "length": 505 }, "evidence": [ { "id": "E1BM88", "url": "https://omabrowser.org/oma/group/E1BM88/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66JZ4-1", "protein_name": "T-cell activation inhibitor, mitochondrial", "gene_name": "TCAIM", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFCHLRPLRRFGLRKVLPHWLHYSRALSGAEAINALRPFYFAVHPDFFGQHPREREVNENSLKRLSVYLENLQKPGFKSLKPTQLTFYIREKTAQNSSEGQEPISTTGFRAVRFTLHSSDLLSTVLYILNSCSLPVEHVQSLNTNVHSQPLKEATGMPDRPIKWHRSYYSFTGFKDPDEDLTHVSRVETTLTSWLGSNGKGAVKKLRNSLPLRKELDRLKNELSELLQLSDIRWQRGWGVAHRCSQLHSLSRLAQQNPGPLQNVKGCTVVFTDRSGMSALGHVMLGTMDVHHHWTRLFESLPSYFDLQRRMSALEAQISNLLGGIQVVYIEELQPALTLDQYYSLLHTFYNQLLRSRVPPHPHPQSLSGLQMILSSDRYAPSLHELGHFDIPALSDPASLQSFMRTKAQQARENMTRREKLKVMENELIQASTKQFSLEKLYKEPSISSRQMVDCCKRLLEQSLPYLHGMHLCVSHFYSVMQDGDLCIPWNWKKGEAMK", "length": 499 }, "evidence": [ { "id": "E1BM88", "url": "https://omabrowser.org/oma/group/E1BM88/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N3R3-1", "protein_name": "T-cell activation inhibitor, mitochondrial", "gene_name": "TCAIM", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFCHLRPMRRLCLEKIFPHWFPFSRALSGAEAVNALRPFYFAVHPDFFGQHPVEREINENSLKRLSVYLENLQKPGFKSLKPTQLTFYVRETDQSSSDGQEPFSTSGFRAVKFTLHTRDLLSTVLYILNSCSLSVEHIQSLNTNMHTQPLKEAKRMPDRPIKWDKSYYSFTGFKDPDEDLEQVSRVETTLTSWLDNNGKSAVKKLKNSLPLRKELDRLKDELSHQLQLSDIRWQRSWGIAHRCSQLHSLSRLAQQNLETLKKAKGCTIIFTDRSGMSAVGHVMLGTMDVHHHWTKLFERLPSYFDLQRRLMILEDQISYLLGGIQVVYIEELQPVLTLEEYYSLLDVFYNRLLKSRILFHPRSLRGLQMILNSDRYAPSLHELGHFNIPTLCDPANLQWFILTKAQQARENMKRKEELKVIENELIQASTKKFSLEKLYKEPSISSIQMVDCCKRLLEQSLPYLHGMHLCISHFYSVMQDGDLCIPWNWKNGEAIK", "length": 496 }, "evidence": [ { "id": "E1BM88", "url": "https://omabrowser.org/oma/group/E1BM88/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VRT6-1", "protein_name": "T-cell activation inhibitor, mitochondrial", "gene_name": "Dmel\\CG13295", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSMSLGSKIRKLVTSRRHFLLLRRSLNQDLTTALRPFYFAVHPDFFAQHPEQRNTNENSLKLLSEHLEALYERRQRSGDTQVLKFYVRTSSDADKRDSFKLIQIRTDWQSTRDPKTFIQGLLESCNLSTEYVKNIKAQPEPPKTSGLDFKPSHDYHYDMEFAEFETQLKNERASKRPVLTTWLEENAGTAKQRSKETADLQAEIDKLKKMLVEKLELQDARYECGWNIEHYRGCLKTLERLSNTHLLEMASLKGRIVVFAPFTGISLEGHVMLFTGDVLSTWIDFIKNIPHHDAYLKVVPVYERTLSQVLLNIQIGRRKFMPKQQASGYASYLMKVTTSLSDYLGKQKYPPEWPKTLKEFTIVVESEAGPLMVSPTGQFITPATCPGSILVDFISVNLELARERMKKYAQDKHIEQELMDSCIKQLQLQSLTKDDAITPDKMITSLRDLYQLQLKELQGCKLHITHYYSVLTDGVVCIPWDFLQR", "length": 485 }, "evidence": [ { "id": "E1BM88", "url": "https://omabrowser.org/oma/group/E1BM88/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "E1BM88", "url": "https://www.uniprot.org/uniprotkb/E1BM88" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BM88-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 496, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BM88-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BM88" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM88" }, { "id": "PF14687", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14687" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF4460", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 133, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "E1BM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM88" }, { "id": "PF14688", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14688" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF4461", "eco_id": "ECO_0000259", "start_pos": 188, "end_pos": 490, "start_aa": "Thr", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BM99-1", "uniprot_ac": "E1BM99", "uniprot_id": "E1BM99_BOVIN", "mass": { "chemical_mass": 152632.0, "monoisotopic_mass": 152632.0 }, "refseq": {}, "gene_names": [ { "name": "ABCC12", "type": "recommended", "evidence": [ { "id": "E1BM99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM99" } ] } ], "protein_names": [ { "name": "ATP-binding cassette sub-family C member 12", "type": "recommended", "evidence": [ { "id": "E1BM99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM99/entry#names_and_taxonomy" } ] }, { "name": "Multidrug resistance-associated protein 9", "type": "synonym", "evidence": [ { "id": "E1BM99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM99/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Probable transporter, its substrate specificity is unknown.", "evidence": [ { "database": "UniProtKB", "id": "E1BM99", "url": "https://www.uniprot.org/uniprotkb/E1BM99#function" }, { "database": "UniProtKB", "id": "ARBA00055586", "url": "https://www.uniprot.org/uniprotkb/ARBA00055586#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BM99", "url": "https://www.uniprot.org/uniprotkb/E1BM99" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ABCC12", "url": "https://www.uniprot.org/uniprotkb/E1BM99", "locus": { "chromosome": "18", "start_pos": 16485763, "end_pos": 16546635, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000044191", "url": "https://www.ensembl.org/id/ENSBTAG00000044191" } ] } } ], "crossref": [ { "id": "ENSBTAG00000044191", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000044191", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03244", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03244", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03250", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03250", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18592", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18592", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18599", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18599", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BM99", "url": "https://www.orthodb.org/?gene=E1BM99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24223", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24223", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24223:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24223:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00664", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00664", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9S355", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S355", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S355-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S355-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SBK3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SBK3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM99", "url": "https://www.uniprot.org/uniprotkb/E1BM99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM99-1", "url": "https://www.uniprot.org/uniprotkb/E1BM99-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGDGPYLISDLDRRGQRRSFTERYDPSLKTMIPVRPYARLAPNPVDDAGLLSFATFSWLTPVMVRGYQHTLTVDTLPPLSLYDSSDTNAKRFRILWDEEVERMGPEKASLGRVVWKFQRTRVLMDIVVNILCIIMAAIGPTVIIHQILQQTESVSRKVWIGVGLCAALFTTEFTKVLFWALAWAINYRTAIRLKVAVSTLVFENLVSFKMLTHISVGEVLNILSSDSYSLFEAALFCPLPATIPILMAVCAVYAFFILGPTALIGISVYLLFIPIQMFLAKLNSAFRRSAISVTDKRVQTMNEFLTCIKLIKMYAWEKSFTNTIRGIRKKERKLLEKAGFVQSGNSALAPIASTIAIVLTFTCHILLRRKLTAPVAFSVIAMFNVMKFSIAILPFSVKAAAEANVSLRRMKKILIAKSPPSYITQPEDPDTVLLLANATLTWEQETSRKSGLKKMQNQKKHFLKKQRPEAYNLSPSAQGAPDEEERHDSPKSVLHNISFVVRKGKILGICGNVGSGKSSLIAALLGQMQLQQGIVAVNGTLAYVSQQAWIFHGNVRENILFGEKYDHQRYQHAVRVCALQEDLSSLPYGDLTEIGERGLNLSGGQRQRISLARAIYSNHEIYLLDDPLSAVDAHVGKHVFEECIKKALRGKTVVLVTHQLQFLESCDEVILLEDGEICEKGTHKELMEERGRYAKLIHNLRGLQFKDPEHMYDAAAVEALKESPFERNEDAGTIILAPGDEKREGKESETESEFVDIKVPPHQLIQTESPREGTVTWKTYHTYIKASGGYLLSLFVVSFFLLMIGSSAFSSWWLGVWLDKGSQMKCGPHSNMSTCEVGMVLADSGLRVYQWVYPGSMVSILVFGITKGFMFTKTTLMASSSLHDRVFDKILESPMSFFDRTPTGRLMNRFSKDMDELDVRLPFHAENFLQQFFMVLFILMILAAVFPAVLLVLAILAVGFFILLRVFHRGIQELKKVENISRSPWFSHITSSMQGLGTIHAYNRREDCVSNHLLYFNCALRWFALRMDVLMNIVTFIVALLVTLSFSSISASSKGLSLSYIIQLSGLLQVCVRTGTETQAKFTSVELLREYISTCVPERTHRLKVGTCPHDWPSHGEITFRDYQMRYRDDSPLVLNGLNLNIQSGQTVGIVGRTGSGKSSLGMALFRLVEPTGGTILIDGVDICTVDLEDLRTKLTVIPQDPVLFVGTVRYNLDPFESHSDEMLWQVLERTFMRDTIMKLPEKLQAEVTENGENFSVGERQLLCMARALLRDSKIILLDEATASMDSKTDTLVQNTIKDAFKDCTVLTIAHRLNTVLNCDRVLVMENGKVVEFDKPEVLAEKPGSAFSMLLAAENKVRI", 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subfamily C member 12 OS=Bos taurus OX=9913 GN=ABCC12 PE=4 SV=1 CANONICAL=E1BM99-1" }, "locus": { "chromosome": "18", "start_pos": 16546587, "end_pos": 16518279, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000111480.1", "url": "https://www.ensembl.org/id/ENSBTAT00000111480.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080353.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080353.1" } ] } }, { "isoform_ac": "A0AAA9SBK3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBK3/entry", "sequence": { "sequence": "MRYRDDSPLVLNGLNLNIQSGQTVGIVGRTGSGKSSLGMALFRLVEPTGGTILIDGVDICTVDLEDLRTKLTVIPQDPVLFIMKLPEKLQAEVTENGENFSVGERQLLCMARALLRDSKIILLDEATASMDSKTDTLVQNTIKDAFKDCTVLTIAHRLNTVLNCDRVLVMENGKVVEFDKPEVLAEKPGSAFSMLLAAENKVRI", "length": 204, "header": "tr|A0AAA9SBK3-1|A0AAA9SBK3_BOVIN Computationally mapped isoform of ATP binding cassette subfamily C member 12 OS=Bos taurus OX=9913 GN=ABCC12 PE=4 SV=1 CANONICAL=E1BM99-1" }, "locus": { "chromosome": "18", "start_pos": 16491659, "end_pos": 16485775, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000095554.1", "url": "https://www.ensembl.org/id/ENSBTAT00000095554.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082773.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082773.1" } ] } }, { "isoform_ac": "E1BM99-1", "url": "https://www.uniprot.org/uniprotkb/E1BM99/entry", "sequence": { "sequence": "MVGDGPYLISDLDRRGQRRSFTERYDPSLKTMIPVRPYARLAPNPVDDAGLLSFATFSWLTPVMVRGYQHTLTVDTLPPLSLYDSSDTNAKRFRILWDEEVERMGPEKASLGRVVWKFQRTRVLMDIVVNILCIIMAAIGPTVIIHQILQQTESVSRKVWIGVGLCAALFTTEFTKVLFWALAWAINYRTAIRLKVAVSTLVFENLVSFKMLTHISVGEVLNILSSDSYSLFEAALFCPLPATIPILMAVCAVYAFFILGPTALIGISVYLLFIPIQMFLAKLNSAFRRSAISVTDKRVQTMNEFLTCIKLIKMYAWEKSFTNTIRGIRKKERKLLEKAGFVQSGNSALAPIASTIAIVLTFTCHILLRRKLTAPVAFSVIAMFNVMKFSIAILPFSVKAAAEANVSLRRMKKILIAKSPPSYITQPEDPDTVLLLANATLTWEQETSRKSGLKKMQNQKKHFLKKQRPEAYNLSPSAQGAPDEEERHDSPKSVLHNISFVVRKGKILGICGNVGSGKSSLIAALLGQMQLQQGIVAVNGTLAYVSQQAWIFHGNVRENILFGEKYDHQRYQHAVRVCALQEDLSSLPYGDLTEIGERGLNLSGGQRQRISLARAIYSNHEIYLLDDPLSAVDAHVGKHVFEECIKKALRGKTVVLVTHQLQFLESCDEVILLEDGEICEKGTHKELMEERGRYAKLIHNLRGLQFKDPEHMYDAAAVEALKESPFERNEDAGTIILAPGDEKREGKESETESEFVDIKVPPHQLIQTESPREGTVTWKTYHTYIKASGGYLLSLFVVSFFLLMIGSSAFSSWWLGVWLDKGSQMKCGPHSNMSTCEVGMVLADSGLRVYQWVYPGSMVSILVFGITKGFMFTKTTLMASSSLHDRVFDKILESPMSFFDRTPTGRLMNRFSKDMDELDVRLPFHAENFLQQFFMVLFILMILAAVFPAVLLVLAILAVGFFILLRVFHRGIQELKKVENISRSPWFSHITSSMQGLGTIHAYNRREDCVSNHLLYFNCALRWFALRMDVLMNIVTFIVALLVTLSFSSISASSKGLSLSYIIQLSGLLQVCVRTGTETQAKFTSVELLREYISTCVPERTHRLKVGTCPHDWPSHGEITFRDYQMRYRDDSPLVLNGLNLNIQSGQTVGIVGRTGSGKSSLGMALFRLVEPTGGTILIDGVDICTVDLEDLRTKLTVIPQDPVLFVGTVRYNLDPFESHSDEMLWQVLERTFMRDTIMKLPEKLQAEVTENGENFSVGERQLLCMARALLRDSKIILLDEATASMDSKTDTLVQNTIKDAFKDCTVLTIAHRLNTVLNCDRVLVMENGKVVEFDKPEVLAEKPGSAFSMLLAAENKVRI", "length": 1360, "header": "tr|E1BM99-1|E1BM99_BOVIN Isoform 1 of ATP-binding cassette sub-family C member 12 OS=Bos taurus OX=9913 GN=ABCC12 PE=3 SV=4 CANONICAL=E1BM99-1" }, "locus": { "chromosome": "18", "start_pos": 16546587, "end_pos": 16485775, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000060942.4", "url": "https://www.ensembl.org/id/ENSBTAT00000060942.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053282.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053282.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 142, "start_aa": "Thr", "end_pos": 142, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr142", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BM99", "url": "https://www.uniprot.org/uniprotkb/E1BM99" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "E1BM99", "url": "https://www.uniprot.org/uniprotkb/E1BM99" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "E1BM99", "url": "https://www.uniprot.org/uniprotkb/E1BM99" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BM99", "url": "https://www.uniprot.org/uniprotkb/E1BM99" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E1BM99", "url": "https://www.uniprot.org/uniprotkb/E1BM99" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "E1BM99", "url": "https://www.uniprot.org/uniprotkb/E1BM99" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1255, "end_pos": 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"RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179900" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMB5", "url": "https://www.uniprot.org/uniprotkb/E1BMB5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RGS18", "url": "https://www.uniprot.org/uniprotkb/E1BMB5", "locus": { "chromosome": "16", "start_pos": 13120994, "end_pos": 13151444, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013064", "url": "https://www.ensembl.org/id/ENSBTAG00000013064" } ] } } ], "crossref": [ { "id": "E1BMB5", "url": "https://alphafold.ebi.ac.uk/entry/E1BMB5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000013064", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013064", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "613624", "url": "https://www.ncbi.nlm.nih.gov/gene/613624", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:613624", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613624", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TFFKLMH", "url": "https://omabrowser.org/oma/group/TFFKLMH/", 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"https://www.uniprot.org/uniprotkb/E1BMC2" }, { "id": "PS00960", "database": "PROSITE", "url": "https://prosite.expasy.org/PS00960" }, { "id": "PS01203", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01203" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Anti-proliferative protein", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 62, "start_aa": "Tyr", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BMD0-1", "uniprot_ac": "E1BMD0", "uniprot_id": "E1BMD0_BOVIN", "mass": { "chemical_mass": 59853.0, "monoisotopic_mass": 59853.0 }, "refseq": { "ac": "XP_024833285", "name": "DDB1- and CUL4-associated factor 17 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024833285" }, "gene_names": [ { "name": "DCAF17", "type": "recommended", "evidence": [ { "id": "E1BMD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMD0" } ] }, { "name": "DCAF17", "type": "synonym", "evidence": [ { "id": "XP_024833285", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024833285" } ] } ], "protein_names": [ { "name": "DDB1 and CUL4 associated factor 17", "type": "synonym", "evidence": [ { "id": "E1BMD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMD0/entry#names_and_taxonomy" } ] }, { "name": "DDB1- and CUL4-associated factor 17 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024833285", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024833285" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMD0", "url": "https://www.uniprot.org/uniprotkb/E1BMD0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DCAF17", "url": "https://www.uniprot.org/uniprotkb/E1BMD0", "locus": { "chromosome": "2", "start_pos": 25002407, "end_pos": 25028982, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007683", "url": "https://www.ensembl.org/id/ENSBTAG00000007683" } ] } } ], "crossref": [ { "id": "E1BMD0", "url": "https://alphafold.ebi.ac.uk/entry/E1BMD0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007683", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007683", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "614170", "url": "https://www.ncbi.nlm.nih.gov/gene/614170", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031620", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031620", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:614170", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614170", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IQEMNCC", "url": "https://omabrowser.org/oma/group/IQEMNCC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BMD0", "url": "https://www.orthodb.org/?gene=E1BMD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3N245", "url": "https://www.orthodb.org/?gene=G3N245", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14815", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14815", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14815:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14815:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15802", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15802", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024833285", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024833285", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SXA7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SXA7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T786", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T786", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T786-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T786-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMD0", "url": "https://www.uniprot.org/uniprotkb/E1BMD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMD0-1", "url": "https://www.uniprot.org/uniprotkb/E1BMD0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N245", "url": "https://www.uniprot.org/uniprotkb/G3N245", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N245-1", "url": "https://www.uniprot.org/uniprotkb/G3N245-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPSQKPNVCGRLSRRALGFFSRDAGMVQRTNLGILRALVCQESTKFKNVWTTHSKSPIAYERGRIYFNNYRCCISSVASEPRKLYEMPRCSKSEKIEDALLWECPVGEMLPSPSDYKSSLIALTAHNWLLRISATTGKVLEKIYLASYCKFRYLSWDTPQEVIAVKSAQNKSSTLARQAGIQQPVLLYLAVFHVLPFSLIGILEINKKIFGNVTDATLSHGILIVMYSSGLVRLYSFQAITKQFMQQKLDLGCACRWGGTTGTVGEAPFGIPCNIKITDTPPLLFEVSSLENAFQIGGHPWHYIITPNKKKQKGVFHICALKDNSLAKNGIQEMECCSLESDWIYFHPDASGRIIHVGPNQVKVLKLSEVENNSAQHQISEDFVILANRERNKNENLPTVTASGRVVKRSFTILDDDPEQETFKIVDYEDELDLLSVVAVTQIDAEGKAHLDFHCNEYGTLLKSIPLMESWDVTYSHEVYFDRDLVLHIEQKPSRVFSCYVYQMVCDPGEEEETTDKRNKTDHNNFTF", "length": 529, "header": "tr|E1BMD0-1|E1BMD0_BOVIN Isoform 1 of DDB1 and CUL4 associated factor 17 OS=Bos taurus OX=9913 GN=DCAF17 PE=4 SV=4 CANONICAL=E1BMD0-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SXA7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXA7/entry", "sequence": { "sequence": "MGRVITALKLGESTKFKNVWTTHSKSPIAYERGRIYFNNYRCCISSVASEPRKLYEMPRCSKSEKIEDALLWECPVGEMLPSPSDYKSSLIALTAHNWLLRISATTGKVLEKIYLASYCKFRYLSWDTPQEVIAVKSAQNKSSTLARQAGIQQPVLLYLAVFHVLPFSLIGILEINKKIFGNVTDATLSHGILIVMYSSGLVRLYSFQAITKQFMQQKLDLGCACRWGGTTGTVGEAPFGIPCNIKITDTPPLLFEVSSLENAFQIGGHPWHYIITPNKKKQKGVFHICALKDNSLAKNGIQEMECCSLESDWIYFHPDASGRIIHVGPNQVKVLKLSEVENNSAQHQISEDFVILANRERNKNENLPTVTASGRVVKRSFTILDDDPEQETFKIVDYEDELDLLSVVAVTQIDAEGKAHLDFHCNEYGTLLKSIPLMESWDVTYSHEVYFDRDLVLHIEQKPSRVFSCYVYQMVCDPGEEEETTDKRNKTDHNNFTF", "length": 498, "header": "tr|A0AAA9SXA7-1|A0AAA9SXA7_BOVIN Computationally mapped isoform of DDB1 and CUL4 associated factor 17 OS=Bos taurus OX=9913 GN=DCAF17 PE=4 SV=1 CANONICAL=E1BMD0-1" }, "locus": { "chromosome": "2", "start_pos": 25028555, "end_pos": 25003764, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109338.1", "url": "https://www.ensembl.org/id/ENSBTAT00000109338.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091098.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091098.1" } ] } }, { "isoform_ac": "A0AAA9T786-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T786/entry", "sequence": { "sequence": "MGPSQKPNVCGRLSRRALGFFSRDAGMVQRTNLGILRALVCQESTKFKNVWTTHSKSPIAYERGRIYFNNYRCCISSVASEPRKLYEMPRCSKSEKIEDALLWECPVGEMLPSPSDYKSSLIALTAHNWLLRISATTGKVLEKIYLASYCKFRYLSWDTPQEVIAVKSAQNKSSTLARQAGIQQPVLLYLAVFHVLPFSLIGILEINKKIFGNVTDATLSHGILIVMYSSGLVRLYSFQAITKQFMQQKLDLGCACRWGGTTGTVGEAPFGIPCNIKITDTPPLLFEVSSLENAFQIGGHPWHYIITPNKKKQKGVFHICALKDNSLAKNGIQEMECCSLESDWIYFHPDASGRIIHVGPNQVKVLKLSEVENNSAQHQISEDFVILANRERNKNENLPTVTASGRVVKRSFTILDDDPEQETFKIVDYEDELDLLSVVAVTQIDAEGKAHLDFHCNEYGTLLKSIPLMESWDVTYSHEVYFDRDLVLHIEQKPSRVFSCYVYQMDGMEF", "length": 510, "header": "tr|A0AAA9T786-1|A0AAA9T786_BOVIN Computationally mapped isoform of DDB1 and CUL4 associated factor 17 OS=Bos taurus OX=9913 GN=DCAF17 PE=4 SV=1 CANONICAL=E1BMD0-1" }, "locus": { "chromosome": "2", "start_pos": 25028815, "end_pos": 25003411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000117324.1", "url": "https://www.ensembl.org/id/ENSBTAT00000117324.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094621.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094621.1" } ] } }, { "isoform_ac": "E1BMD0-1", "url": "https://www.uniprot.org/uniprotkb/E1BMD0/entry", "sequence": { "sequence": "MGPSQKPNVCGRLSRRALGFFSRDAGMVQRTNLGILRALVCQESTKFKNVWTTHSKSPIAYERGRIYFNNYRCCISSVASEPRKLYEMPRCSKSEKIEDALLWECPVGEMLPSPSDYKSSLIALTAHNWLLRISATTGKVLEKIYLASYCKFRYLSWDTPQEVIAVKSAQNKSSTLARQAGIQQPVLLYLAVFHVLPFSLIGILEINKKIFGNVTDATLSHGILIVMYSSGLVRLYSFQAITKQFMQQKLDLGCACRWGGTTGTVGEAPFGIPCNIKITDTPPLLFEVSSLENAFQIGGHPWHYIITPNKKKQKGVFHICALKDNSLAKNGIQEMECCSLESDWIYFHPDASGRIIHVGPNQVKVLKLSEVENNSAQHQISEDFVILANRERNKNENLPTVTASGRVVKRSFTILDDDPEQETFKIVDYEDELDLLSVVAVTQIDAEGKAHLDFHCNEYGTLLKSIPLMESWDVTYSHEVYFDRDLVLHIEQKPSRVFSCYVYQMVCDPGEEEETTDKRNKTDHNNFTF", "length": 529, "header": "tr|E1BMD0-1|E1BMD0_BOVIN Isoform 1 of DDB1 and CUL4 associated factor 17 OS=Bos taurus OX=9913 GN=DCAF17 PE=4 SV=4 CANONICAL=E1BMD0-1" }, "locus": { "chromosome": "2", "start_pos": 25028815, "end_pos": 25003764, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000010105.7", "url": "https://www.ensembl.org/id/ENSBTAT00000010105.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000010105.7", "url": "https://www.ensembl.org/id/ENSBTAP00000010105.7" } ] } }, { "isoform_ac": "G3N245-1", "url": "https://www.uniprot.org/uniprotkb/G3N245/entry", "sequence": { "sequence": "MGPSQKPNVCGRLSRRALGFFSRDAGMVQRTNLGILRALVCQESTKFKNVWTTHSKSPIAYERGRIYFNNYRCCISSVASEPRKLYEMPRCSKSEKIEDALLWECPVGEMLPSPSDYKSSLIALTAHNWLLRISATTGKVLEKIYLASYCKFRYLSWDTPQEVIAVKSAQNKSSTLARQAGIQQPVLLYLAVFHVLPFSLIGILEINKKIFGNVTDATLSHGILIVMYSSGLVRLYSFQAITKQFMQQKLDLGCACRWGGTTGTVGEAPFGIPCNIKITDTPPLLFEVSSLENAFQIGGHPWHYIITPNKKKQKGVFHICALKDNSLNENLPTVTASGRVVKRSFTILDDDPEQETFKIVDYEDELDLLSVVAVTQIDAEGKAHLDFHCNEYGTLLKSIPLMESWDVTYSHEVYFDRDLVLHIEQKPSRVFSCYVYQMVCDPGEEEETTDKRNKTDHNNFTF", "length": 462, "header": "tr|G3N245-1|G3N245_BOVIN Computationally mapped isoform of DDB1 and CUL4 associated factor 17 OS=Bos taurus OX=9913 GN=DCAF17 PE=4 SV=2 CANONICAL=E1BMD0-1" }, "locus": { "chromosome": "2", "start_pos": 25028815, "end_pos": 25003764, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064596.2", "url": "https://www.ensembl.org/id/ENSBTAT00000064596.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055950.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055950.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:614170", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614170", "resource": "KEGG Pathway" }, { "id": "R-BTA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8951664", "resource": "Reactome", "description": "Neddylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D0URK7-1", "protein_name": "DDB1 and CUL4 associated factor 17", "gene_name": "DCAF17", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGPSQKPNVCCRLSRRALGFFSRDAGVVQRTNLGILRALVCQESTKFKNVWTTHSKSPIAYERGRIYFDNYRCCVSSVASEPRKLYEMPKCSKSEKIEDALLWECPVGEMLPNSSDYKSSLIALTAHNWLLRISATTGKVLEKIYLASYCKFRYLSWDTPQEVIAIKSAQNKSSALARQAGIQQPVLLYLAVFHVLPFSLIGILEINKKIFGNVTDATLSHGILIVMYSSGLVRLYSFQAITEQFMQQKLDLGCACRWGGTTGTVGEAPFGIPCNIKITDTPPLLFEVSSLENAFQIGGHPWHYIITPNKKKQKGVFHICALKDNSLAKNGIQEMECCSLESDWIYFHPDASGRIIHVGPNQVKVLKLSEVENNSAQHQISEDFVILANREKNKNENLPTVTASGRVVKKSFNLLDDDPEQETFKIVDYEDELDLLSVVAVTQIDAEGKAHLDFHCNEYGTLLKSIPLVESWDVTYSHEVYFDRDLVLHIEQKPSRVFSCYVYQMVCDHGDEEETTNRSCKKDCGNFKF", "length": 529 }, "evidence": [ { "id": "E1BMD0", "url": "https://omabrowser.org/oma/group/E1BMD0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "B1H299-1", "protein_name": "DDB1- and CUL4-associated factor 17", "gene_name": "Dcaf17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRTRKANVCPRLSRRALGFYTRDAGVVQRTNLGILRALVCQESTKFKNVWTTHSKSPIAYERGRIYFDNYRCCVSSVASEPRKLYEMPKCSKSEKIEDALLWECPVGEILPDPSDYKSSLIALTAHNWLLRISATTGEILEKIYLASYCKFRYLSWDTPQEVIAVKSAQNKGSAAARQAGTQPPVLLYLAVFRVLPFSLVGILEINRKVFENVTDATLSHGILIVMYSSGLVRLYSFQAIIEQFMQQKLDLGCACSQGGTTGTVGEAPFGIPCNVKITDSPPPLFEVSSLENAFQIGGHPWHYIITPNKKKQKGVFHICALKDNSLAKNGIQEMECCSLESDWIYFHPDASGRIIHVGPNQVKVLKLSEVENNSSQHQISEDFVIWANREDRKENLITVTASGRVVKRNVNLLDDDPEQETFKVVDYEDELNLLSVVAVTQIDAEGKAHLDFHCNEYGTLLKSIPLVESWDVVCITTGTLSCKGFLYKRHLLGHVLVSPDSPVP", "length": 505 }, "evidence": [ { "id": "E1BMD0", "url": "https://omabrowser.org/oma/group/E1BMD0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3GUA9-1", "protein_name": "DDB1- and CUL4-associated factor 17 isoform X1", "gene_name": "Dcaf17", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGPTPKANVCRRLSRRALGFFARDAGVVQRTNLGILRALVCQESTKFKNVWTTHSKSPIAYERGRIYFDNYRCCVSSVASEPRKLYEMPKCSKSEKIEDALLWECPVGEILPNPSDYKSSLIALTAHNWLLRISATTGEILEKIYLASYCKFRYLSWDTPQEVIAVKSAQNKGSAVARQVGTQQPVLLYLAVFRVLPFSLVGILEINKKVFANVTDATLSHGILIVMYSSGLVRLYSFQAIIEQFMQQKLDLGCACSQGGTTGTVGEAPFGIPCNVKITDSPCPLFEVSSLENAFQIGGHPWHYIITPNKKKQKGVFHICALKDNSLAKNGIQEMECCSLESDWIYFHPDASGRIIHVGPNQVKVLKLSEVENNSSQHQISEDFVIWANREDRNENLITVTASGRVVKRNVNLLDDDPEQETFKIVDYEDELDLLSVVAVTQIDAEGKAHLDFHCNEYGTLLKSIPLVESWDVTYSHEVYFDRDLVLHIEQKPNRVFSCYVYQMVCDPGEEEDIVNRSD", "length": 519 }, "evidence": [ { "id": "E1BMD0", "url": "https://omabrowser.org/oma/group/E1BMD0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3TUL7-1", "protein_name": "DDB1- and CUL4-associated factor 17", "gene_name": "Dcaf17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRTRKANVCRRLSRRALGFYARDAGVVQRTNLGILRALVCQESTKFKNVWTTHSKSPIAYERGRIYFDNYRCCVSSVASEPRKLYEMPKCSKSEKIEDALLWECPVGDILPDPSDYKSSLIALTAHNWLLRISATTGEVLEKIYLASYCKFRYLSWDTPQEVIAVKSAQNKGSAAARQAGTSPPVLLYLAVFRVLPFSLVGILEINKKVFENVTDATLSHGILIVMYSSGLVRLYSFQAIIEQFMQQKLDLGCACSQGGTTGTVGEAPFGIPCNVKITDSPPPLFEVSSLENAFQIGGHPWHYIITPNKKKQKGVFHICALKDNSLAKNGIQEMECCSLESDWIYFHPDASGRIIHVGPNQVKVLKLSEVENDSSQHQISEDFVIWAKREDRKENLITVTASGRVVKRNVSLLDDDPEQETFKIVDYEDELDLLSVVAVTQIDAEGKAHLDFHCNEYGTLLKSIPLVESWDVTYSHEVYFDRDLVLHIEQKPNRVFSCYVYQMVCDPGEEEEAVNRSG", "length": 519 }, "evidence": [ { "id": "E1BMD0", "url": "https://omabrowser.org/oma/group/E1BMD0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5H9S7-1", "protein_name": "DDB1- and CUL4-associated factor 17", "gene_name": "DCAF17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGPTRKPNVCSRLSRRALGCFSRDAGVVQRTNLGILRALVCQESTKFKNVWTTHSRSPIAYERGRIYFDNYRRCVSSVASEPRKLYEMPKCSKSEKIEDALLWECPVGDILPNSSDYKSSLIALTAHNWLLRISATTGKILEKIYLAPYCKFRYLSWDTPQEVIAVKSAQNRGSAVARQAGIQQHVLLYLAVFRVLPFSLVGILEINKKIFGNVTDATLSHGILIVMYSSGLVRLYSFQTIAEQFMQQKLDLGCACRWGGTTGTVGEAPFGIPCNIKITDMPPLLFEVSSLENAFQIGGHPWHYIVTPNKKKQKGVFHICALKDNSLAKNGIQEMDCCSLESDWIYFHPDASGRIIHVGPNQVKVLKLTEIENNSSQHQISEDFVILANRENHKNENVLTVTASGRVVKKSFNLLDDDPEQETFKIVDYEDELDLLSVVAVTQIDAEGKAHLDFHCNEYGTLLKSIPLVESWDVTYSHEVYFDRDLVLHIEQKPNRVFSCYVYQMICDTGEEEETINRSC", "length": 520 }, "evidence": [ { "id": "E1BMD0", "url": "https://omabrowser.org/oma/group/E1BMD0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BMD0", "url": "https://www.uniprot.org/uniprotkb/E1BMD0" } ], "pmid": "" }, { "name": "Cul4-RING E3 ubiquitin ligase complex", "id": "GO:0080008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080008", "evidence": [ { "database": "UniProtKB", "id": "E1BMD0", "url": "https://www.uniprot.org/uniprotkb/E1BMD0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "E1BMD0", "url": "https://www.uniprot.org/uniprotkb/E1BMD0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 373, "end_pos": 375, "annotation": "n_glycosylation_sequon" }, { "start_pos": 520, "end_pos": 522, "annotation": "n_glycosylation_sequon" }, { "start_pos": 526, "end_pos": 528, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMD0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 529, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMD0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMD0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 171, "end_pos": 173 }, { "start_pos": 213, "end_pos": 215 }, { "start_pos": 373, "end_pos": 375 }, { "start_pos": 520, "end_pos": 522 }, { "start_pos": 526, "end_pos": 528 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BMD2-1", "uniprot_ac": "E1BMD2", "uniprot_id": "E1BMD2_BOVIN", "mass": { "chemical_mass": 39295.0, "monoisotopic_mass": 39295.0 }, "refseq": { "ac": "NP_001179463", "name": "homeobox protein Mohawk", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179463" }, "gene_names": [ { "name": "MKX", "type": "recommended", "evidence": [ { "id": "E1BMD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMD2" } ] }, { "name": "MKX", "type": "synonym", "evidence": [ { "id": "NP_001179463", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179463" } ] } ], "protein_names": [ { "name": "Mohawk homeobox", "type": "synonym", "evidence": [ { "id": "E1BMD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMD2/entry#names_and_taxonomy" } ] }, { "name": "homeobox protein Mohawk", "type": "synonym", "evidence": [ { "id": "NP_001179463", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179463" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMD2", "url": "https://www.uniprot.org/uniprotkb/E1BMD2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MKX", "url": "https://www.uniprot.org/uniprotkb/E1BMD2", "locus": { "chromosome": "13", "start_pos": 36892825, "end_pos": 36823229, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007678", "url": "https://www.ensembl.org/id/ENSBTAG00000007678" } ] } } ], "crossref": [ { "id": "E1BMD2", "url": "https://alphafold.ebi.ac.uk/entry/E1BMD2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007678", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007678", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "521239", "url": "https://www.ncbi.nlm.nih.gov/gene/521239", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:521239", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:521239", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TSTAMMG", "url": "https://omabrowser.org/oma/group/TSTAMMG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BMD2", "url": "https://www.orthodb.org/?gene=E1BMD2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11211", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11211", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11211:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11211:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179463", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179463", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M4Z3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4Z3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M4Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4Z3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMD2", "url": "https://www.uniprot.org/uniprotkb/E1BMD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMD2-1", "url": "https://www.uniprot.org/uniprotkb/E1BMD2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNTIVFNKLSGAVLFEDRGAPERDRGGRPYGGVLDSPHARPEVGITDGPPLKDNLGLRHRRTGARQNGGKVRHKRQALQDMARPLKQWLYKHRDNPYPTKTEKILLALGSQMTLVQVSNWFANARRRLKNTVRQPDLSWALRIKLYNKYVQGNAERLSVSSDDSCSEDGENPPRNHMNDGGYNNPVHHPVIKSESSVIKAGVRPESRASEDYVSPPKYKSSLLNRYLNDSLRHVMVTNAAMMGKTRQRNHSGSFSSNEFEEELVSPSSSETEGNFVYRTDTLENGSNKGDSAATRKGPSKDDTYWKEINAAMALTNLAQGKDKPQGTTSCIIQKSSHIAEVKTVKVPLVPQF", "length": 352, "header": "tr|E1BMD2-1|E1BMD2_BOVIN Isoform 1 of Mohawk homeobox OS=Bos taurus OX=9913 GN=MKX PE=3 SV=2 CANONICAL=E1BMD2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M4Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4Z3/entry", "sequence": { "sequence": "MNTIVFNKLSGAVLFEDRGAPERDRGGRPYGGVLDSPHARPEVGITDGPPLKDNLGLRHRRTGARQNGGKVRHKRQALQDMARPLKQWLYKHRDNPYPTKTEKILLALGSQMTLVQVSNWFANARRRLKNTVRQPDLSWALRIKLYNKYVQGNAERLSVSSDDSCSEDGENPPRNHMNDGGYNNPVHHPVIKSESSVIKAGVRPESRASEDYVSPPKYKSSLLNRYLNDSLRHVMVTNAAMMGKTRQRNHSGSFSSNEFEEELVSPSSSETEGNFVYRTDCTAAAARSLQLCPTLCDPKDGSPPGSPVPGILQARTLEWVAISFSNA", "length": 327, "header": "tr|A0A3Q1M4Z3-1|A0A3Q1M4Z3_BOVIN Computationally mapped isoform of Mohawk homeobox OS=Bos taurus OX=9913 GN=MKX PE=3 SV=1 CANONICAL=E1BMD2-1" }, "locus": { "chromosome": "13", "start_pos": 36851562, "end_pos": 36825943, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067860.3", "url": "https://www.ensembl.org/id/ENSBTAT00000067860.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065316.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065316.2" } ] } }, { "isoform_ac": "E1BMD2-1", "url": "https://www.uniprot.org/uniprotkb/E1BMD2/entry", "sequence": { "sequence": "MNTIVFNKLSGAVLFEDRGAPERDRGGRPYGGVLDSPHARPEVGITDGPPLKDNLGLRHRRTGARQNGGKVRHKRQALQDMARPLKQWLYKHRDNPYPTKTEKILLALGSQMTLVQVSNWFANARRRLKNTVRQPDLSWALRIKLYNKYVQGNAERLSVSSDDSCSEDGENPPRNHMNDGGYNNPVHHPVIKSESSVIKAGVRPESRASEDYVSPPKYKSSLLNRYLNDSLRHVMVTNAAMMGKTRQRNHSGSFSSNEFEEELVSPSSSETEGNFVYRTDTLENGSNKGDSAATRKGPSKDDTYWKEINAAMALTNLAQGKDKPQGTTSCIIQKSSHIAEVKTVKVPLVPQF", "length": 352, "header": "tr|E1BMD2-1|E1BMD2_BOVIN Isoform 1 of Mohawk homeobox OS=Bos taurus OX=9913 GN=MKX PE=3 SV=2 CANONICAL=E1BMD2-1" }, "locus": { "chromosome": "13", "start_pos": 36892346, "end_pos": 36825943, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000010101.8", "url": "https://www.ensembl.org/id/ENSBTAT00000010101.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000010101.5", "url": "https://www.ensembl.org/id/ENSBTAP00000010101.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:521239", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:521239", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZUL2-1", "protein_name": "Mohawk homeobox", "gene_name": "Mkx", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNTIVFNKLGGAVIFDDRGTPDRERGSRPYGGVLDNPHTGPEVGIPDGPPLKDNLSLRHRRTGARPGGKVRHKRQALQDMARPLKQWLYKHRDNPYPTKTEKILLALGSQMTLVQVSNWFANARRRLKNTVRQPDLSWALRIKLYNKYVQGNAERLSVSSADDSCSEDGENPPRTHMNEEGYSTPAHHTVIKGESSAIKAGGRPESRAAEDYVSPPKYKSSLLNRYLNDSLRHVMATSTAMMGKTRRRNHSGSFSSNEFEEELVSPSSSETEGTFVYRTDTPDIGSTKGDKGDSTANRRGPSKDDTHWKEINAAMALTNLAQGKDEAQGTTTSCIIQKSSHIAEVKTVKLPLVQHF", "length": 356 }, "evidence": [ { "id": "E1BMD2", "url": "https://omabrowser.org/oma/group/E1BMD2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H3P0-1", "protein_name": "Homeobox protein Mohawk", "gene_name": "Mkx", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNTIVFNKLGGAVLFEDRGTPERERGSRPYGGVLDNPHTRPEVGIPDGPPLKDNLGLRHRRTGVRQNGGKVRHKRQALQDMARPLKQWLYKHRDNPYPTKTEKILLALGSQMTLVQVSNWFANARRRLKNTVRQPDLSWALRIKLYNKYVQGNAERLSVSSDDSCSEDGENPPRNHMNEAGYSTPAHHTVIKGESSVIKAGVRPESRAAEDYVSPPKYKSSLLNRYLNDSLRHVMATSTAMMGKTRQRNHSGSFSSNEFEEELVSPSSSETEGNFVYRTDTLDIGSNKGDSAANRRGPSKDDTYWKEINAAMALTNLAQGKDEVQGTTSCIIQKSSHIAEVKTVKLPLAQRF", "length": 352 }, "evidence": [ { "id": "E1BMD2", "url": "https://omabrowser.org/oma/group/E1BMD2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8BIA3-1", "protein_name": "Homeobox protein Mohawk", "gene_name": "Mkx", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTIVFNKLGGAVLFEDRGTPDRERGSRTFSGFLDNPHTGPEVGIPDGPPLKDNLSLRHRRTGARQNGGKVRHKRQALQDMARPLKQWLYKHRDNPYPTKTEKILLALGSQMTLVQVSNWFANARRRLKNTVRQPDLSWALRIKLYNKYVQGNAERLSVSSDGDSCSEDGENPPRNHMNEEGYSTPAHHTVIKGESSAIKAGGRPESRAAEDYVSPPKYKSSLLNRYLNDSLRHVMATSTAMMGKTRRRNHSGSFSSNEFEEELVSPSSSETEGTFVYRTDTPDIGSTKGDSAANRRGPSKDDTYWKEINAAMALTNLAQGKDEVQGTTSCIIQKSSHIAEVKTVKLPLVQRF", "length": 353 }, "evidence": [ { "id": "E1BMD2", "url": "https://omabrowser.org/oma/group/E1BMD2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IYA7-1", "protein_name": "Homeobox protein Mohawk", "gene_name": "MKX", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNTIVFNKLSGAVLFEDGGASERERGGRPYSGVLDSPHARPEVGIPDGPPLKDNLGLRHRRTGARQNGGKVRHKRQALQDMARPLKQWLYKHRDNPYPTKTEKILLALGSQMTLVQVSNWFANARRRLKNTVRQPDLSWALRIKLYNKYVQGNAERLSVSSDDSCSEDGENPPRTHMNEGGYNTPVHHPVIKSENSVIKAGVRPESRASEDYVAPPKYKSSLLNRYLNDSLRHVMATNTTMMGKTRQRNHSGSFSSNEFEEELVSPSSSETEGNFVYRTDTLENGSNKGESAANRKGPSKDDTYWKEINAAMALTNLAQGKDKLQGTTSCIIQKSSHIAEVKTVKVPLVQQF", "length": 352 }, "evidence": [ { "id": "E1BMD2", "url": "https://omabrowser.org/oma/group/E1BMD2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "E1BMD2", "url": "https://www.uniprot.org/uniprotkb/E1BMD2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BMD2", "url": "https://www.uniprot.org/uniprotkb/E1BMD2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "E1BMD2", "url": "https://www.uniprot.org/uniprotkb/E1BMD2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BMD2", "url": "https://www.uniprot.org/uniprotkb/E1BMD2" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BMD2", "url": "https://www.uniprot.org/uniprotkb/E1BMD2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BMD2", "url": "https://www.uniprot.org/uniprotkb/E1BMD2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 228, "end_pos": 230, "annotation": "n_glycosylation_sequon" }, { "start_pos": 249, "end_pos": 251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMD2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 352, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMD2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMD2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BMD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMD2" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Nucleotide_Binding_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000256", "start_pos": 71, "end_pos": 132, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 228, "end_pos": 230 }, { "start_pos": 249, "end_pos": 251 }, { "start_pos": 284, "end_pos": 286 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BMD6-1", "uniprot_ac": "E1BMD6", "uniprot_id": "E1BMD6_BOVIN", "mass": { "chemical_mass": 65715.0, "monoisotopic_mass": 65715.0 }, "refseq": { "ac": "NP_001179520", "name": "lipoma-preferred partner", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179520" }, "gene_names": [ { "name": "LPP", "type": "recommended", "evidence": [ { "id": "E1BMD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMD6" } ] }, { "name": "LPP", "type": "synonym", "evidence": [ { "id": "NP_001179520", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179520" } ] } ], "protein_names": [ { "name": "LIM domain containing preferred translocation partner in lipoma", "type": "synonym", "evidence": [ { "id": "E1BMD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMD6/entry#names_and_taxonomy" } ] }, { "name": "lipoma-preferred partner", "type": "synonym", "evidence": [ { "id": "NP_001179520", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179520" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMD6", "url": "https://www.uniprot.org/uniprotkb/E1BMD6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LPP", "url": "https://www.uniprot.org/uniprotkb/E1BMD6", "locus": { "chromosome": "1", "start_pos": 78452386, "end_pos": 79136219, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000044001", "url": "https://www.ensembl.org/id/ENSBTAG00000044001" } ] } } ], "crossref": [ { "id": "E1BMD6", "url": "https://alphafold.ebi.ac.uk/entry/E1BMD6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000044001", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000044001", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09350", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09350", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09356", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09356", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09436", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09436", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "524132", "url": "https://www.ncbi.nlm.nih.gov/gene/524132", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:524132", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:524132", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GGMDYTY", "url": "https://omabrowser.org/oma/group/GGMDYTY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BMD6", "url": "https://www.orthodb.org/?gene=E1BMD6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24207", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24207", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24207:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24207:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179520", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179520", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1NJ09", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NJ09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NJ09-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NJ09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U1Y4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1Y4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U1Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1Y4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMD6", "url": "https://www.uniprot.org/uniprotkb/E1BMD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMD6-1", "url": "https://www.uniprot.org/uniprotkb/E1BMD6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSHPSWLPPKSTAEPLGHVSARMETTHSFGTPSISVSTQQPPKKFAPVVAPKPKYNPYKQPGGEGDFLPPPPPPLDDSSALPSGSGNFPPPPPLDDNAFRGQGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRPPQGTTSSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTMKPQPAPQAGPIPVAPIGTLKPQPQPVPASYTTASTPSRPTFNVQVKSAQPSSHYMAAPSPGQFYGSGPGAQGYNTQPVPMSGQGPPPSTRGGMDYAYVPPPGLQPEPGYGYAPNQGRYYEPYCAVGPGYGGKNDSDPSYGQQGHPNTWKREQGYTPSGPGNQNPAGMYPVAGPKKTYITDPVPAPCVPPLQPKGGPAGSMGPPAAPSSFRPEDELEHLTKKMLYDMENPPTDEYFGRCARCGENVVGEGTGCTAMDQVFHVDCFTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCSVCSKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVHCYRCEDCGGLLSEGDNQGCYPLDGHILCKTCNSARIRVLTAKASTDL", "length": 614, "header": "tr|E1BMD6-1|E1BMD6_BOVIN Isoform 1 of LIM domain containing preferred translocation partner in lipoma OS=Bos taurus OX=9913 GN=LPP PE=3 SV=1 CANONICAL=E1BMD6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1NJ09-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NJ09/entry", "sequence": { "sequence": "MQASRSGDFLPPPPPPLDDSSALPSGSGNFPPPPPLDDNAFRGQGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRPPQGTTSSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTMKPQPAPQAGPIPVAPIGTLKPQPQPVPASYTTASTPSRPTFNVQVKSAQPSSHYMAAPSPGQFYGSGPGAQGYNTQPVPMSGQGPPPSTRGGMDYAYVPPPGLQPEPGYGYAPNQGRYYEPYCAVGPGYGGKNDSDPSYGQQGHPNTWKREQGYTPSGPGNQNPAGMYPVAGPKKTYITDPVPAPCVPPLQPKGGPAGSMGPPAAPSSFRPEDELEHLTKKMLYDMENPPTDEYFGRCARCGENVVGEGTGCTAMDQVFHVDCFTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCSVCSKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVHCYRCEDCGGLLSEGDNQGCYPLDGHILCKTCNSARIRVLTAKASTDL", "length": 556, "header": "tr|A0A3Q1NJ09-1|A0A3Q1NJ09_BOVIN Computationally mapped isoform of LIM domain containing preferred translocation partner in lipoma OS=Bos taurus OX=9913 GN=LPP PE=1 SV=1 CANONICAL=E1BMD6-1" }, "locus": { "chromosome": "1", "start_pos": 78937736, "end_pos": 78452730, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070743.2", "url": "https://www.ensembl.org/id/ENSBTAT00000070743.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072067.2", "url": "https://www.ensembl.org/id/ENSBTAP00000072067.2" } ] } }, { "isoform_ac": "A0AAA9U1Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1Y4/entry", "sequence": { "sequence": "MERKGAGTPNNLKSTSYSVQLLHAEPERVMVSGIAKCVCLPLSAASVSLIVLAFLFHETVLELRLVYYSQCCCLALFSSMALRDFLPPPPPPLDDSSALPSGSGNFPPPPPLDDNAFRGQGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRPPQGTTSSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTMKPQPAPQAGPIPVAPIGTLKPQPQPVPASYTTASTPSRPTFNVQVKSAQPSSHYMAAPSPGQFYGSGPGAQGYNTQPVPMSGQGPPPSTRGGMDYAYVPPPGLQPEPGYGYAPNQGRYYEPYCAVGPGYGGKNDSDPSYGQQGHPNTWKREQGYTPSGPGNQNPAGMYPVAGPKKTYITDPVPAPCVPPLQPKGGPAGSMGPPAAPSSFRPEDELEHLTKKMLYDMENPPTDEYFGRCARCGENVVGEGTGCTAMDQVFHVDCFTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCSVCSKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVHCYRCEDCGGLLSEGDNQGCYPLDGHILCKTCNSARIRVLTAKASTDL", "length": 632, "header": "tr|A0AAA9U1Y4-1|A0AAA9U1Y4_BOVIN Computationally mapped isoform of LIM domain containing preferred translocation partner in lipoma OS=Bos taurus OX=9913 GN=LPP PE=1 SV=1 CANONICAL=E1BMD6-1" }, "locus": { "chromosome": "1", "start_pos": 78936586, "end_pos": 78452730, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093766.1", "url": "https://www.ensembl.org/id/ENSBTAT00000093766.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103332.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103332.1" } ] } }, { "isoform_ac": "E1BMD6-1", "url": "https://www.uniprot.org/uniprotkb/E1BMD6/entry", "sequence": { "sequence": "MSHPSWLPPKSTAEPLGHVSARMETTHSFGTPSISVSTQQPPKKFAPVVAPKPKYNPYKQPGGEGDFLPPPPPPLDDSSALPSGSGNFPPPPPLDDNAFRGQGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRPPQGTTSSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTMKPQPAPQAGPIPVAPIGTLKPQPQPVPASYTTASTPSRPTFNVQVKSAQPSSHYMAAPSPGQFYGSGPGAQGYNTQPVPMSGQGPPPSTRGGMDYAYVPPPGLQPEPGYGYAPNQGRYYEPYCAVGPGYGGKNDSDPSYGQQGHPNTWKREQGYTPSGPGNQNPAGMYPVAGPKKTYITDPVPAPCVPPLQPKGGPAGSMGPPAAPSSFRPEDELEHLTKKMLYDMENPPTDEYFGRCARCGENVVGEGTGCTAMDQVFHVDCFTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCSVCSKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVHCYRCEDCGGLLSEGDNQGCYPLDGHILCKTCNSARIRVLTAKASTDL", "length": 614, "header": "tr|E1BMD6-1|E1BMD6_BOVIN Isoform 1 of LIM domain containing preferred translocation partner in lipoma OS=Bos taurus OX=9913 GN=LPP PE=3 SV=1 CANONICAL=E1BMD6-1" }, "locus": { "chromosome": "1", "start_pos": 78952922, "end_pos": 78452730, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061134.3", "url": "https://www.ensembl.org/id/ENSBTAT00000061134.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053242.2", "url": "https://www.ensembl.org/id/ENSBTAP00000053242.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:524132", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:524132", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D1N3M6-1", "protein_name": "LIM domain containing preferred translocation partner in lipoma", "gene_name": "LPP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSHPSWLPPKSTAEPLGHVPARMETTHSFGTPSISVSTQQPPKKFAPVVAPKPKYNPYKQPGGEGDFPPPPPPPLDDSSALPSGSGNFPPPPPLDDGAFRAQGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRPPQGSTSSATASPPVSTPVTGHKRMVIPNQPPLTATKKSTLKPQPAPQAGPIPVAPIGTLKPQPQPVPASYTTASTPSRPTFNVQVKSAQPSSHYMATPSPGQFYGPGPGAQGYNTHTVPMSAQGPPPSARGGMDYAFIPPPGLQPEPGYGYAPNQGRYYEAYCPAGPGYGGKSDSDPAYGQQGHPNAWKREQGYAPSGTVNQNPAGMYPVAGPKKTYITDPVSAPCAPPLQPKGGQTGPLGPPAAPPSFRPEDELEHLTKKMLYDMENPPADEYFGRCARCGENVVGEGTGCTAMDQVFHVDCFTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCSVCSKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVHCYRCEDCGGLLSEGDNQGCYPLDGHILCKTCNSARIRVLTAKASTDL", "length": 615 }, "evidence": [ { "id": "E1BMD6", "url": "https://omabrowser.org/oma/group/E1BMD6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5F464-1", "protein_name": "Lipoma-preferred partner homolog", "gene_name": "LPP", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSHPSWLPPKSTNEPVGHVTARMETTHAFGTPSISVSTQQTPKKFAPVVAPKPKYNPYKQPGGDGDFLPPPPPPVDDLGNITSQGAFPPPPPLDDVAFNVQVNPGGKTLEERRSSLDAEIDSLTSILADLESSSPYKPRIQQGSGTSSSAATTPSVSTPVTGHKRMIIPNQPPLTATKKSTAKGPGQPAPIPVTPIGTLKPQPVPASYTTASTPSRPTFNVQVRTAQPSPHYQPPGPQPTHYGSLGPGQPYAAPPARPPGAQQYGSPQPRGPDYGYAPPPARPSEPSYGYAPQQGRYQDPYYGGYGGRNGSEAPYMPQSTWKVEPAYPSSNTVGQAPPGMYQHPGPKKTYITDPVLAPQPLQQKSGYPSSGPTSSTPAFRPEDELEHLTKKMLYDMENPPSDDYFGRCARCGENVVGEGTGCTAMDQVFHVECFTCMMCNNKLRGQPFYAVEKKAYCEPCYINTLEQCSVCAKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGNIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVQCYRCEDCGGLLSEGDNQGCYPLDGHILCKTCNSARIQALTAKASTDL", "length": 604 }, "evidence": [ { "id": "E1BMD6", "url": "https://omabrowser.org/oma/group/E1BMD6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q5XI07-1", "protein_name": "Lipoma-preferred partner homolog", "gene_name": "Lpp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHPSWLPPRSTGEPLGHVPARMETTHSFGTPSISVSTQQPPKKFAPVVAPKPKYNPYKQPGGEGDFLPPPPPPLEDPGTIPSGSGHFPPPPPLDEGAFIVQRGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRAPPGSSSSIASPPVSTPVTGHKRMVIPQQPPLTATKKSATKPQAIPIPVTPIGTLKPQPQPVPASYSTASTSSRPAFNVQVKSAQPSTHYMTGSSSGQMYGPGSRSYNTQQVPLSAQCPPPTTCAGTDYAYIPPSGQQAESGFGYTSNQGRYFEPFFAACPSYGGRNEADPAYGQQVQPNTWKREPGYAAPGAGNQNQPGMYSVSGPKKTYITDPVSAPCAPPVQPKERLVKNQKVLQNVVDDRVHGLRKSGFPAPMGPPSVPPSFRPEDELEHLTKKMLYDMENPPADDYFGRCARCGENVVGEGTGCTAMDQVFHVDCFTCMVCDIKLRGQPFYAVEKKAYCEPCYINTLEQCSVCSKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDACGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVHCYRCEDCGGLLSEGDNQGCYPLDGHILCKSCNSARIRVLTAKASTDL", "length": 632 }, "evidence": [ { "id": "E1BMD6", "url": "https://omabrowser.org/oma/group/E1BMD6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BFW7-1", "protein_name": "Lipoma-preferred partner homolog", "gene_name": "Lpp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSHPSWLPPKSTGEPLGHVPARMETTHSFGNPSISVSTQQPPKKYAPVVAPKPKYNPYKQPGGEGDLLPPPPPPLEDPGTIPPGPGHFPPPPPLDEGAFKVQQGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRPPQGSASSIASPPVSTPVTGHKRMVIPQQPPLTATKKSATKPQPAPQAAPIPVTPIGTLKPQPQPVPASYTTASTSSRPTFNVQVKSAQPSPHYMAGPSSGQIYGPGPRGYNNQPVPVSGQCPPPPTCVGTDYAYIPPSGHPPESGYGYTSNQGRYYEPYYAAGPSYGGRSEGDTAYGQQVQPNTWKREAAYAPPASGNQNHPGMYPVSGPKKTYITDPVSAPCAPPLQPKGGYPGPMGPPSIPPSFRPEDELEHLTKKMLYDMENPPADDYFGRCARCGENVVGEGTGCTAMDQVFHVDCFTCIVCDVKLRGQPFYAVEKKAYCEPCYINTLEQCSVCSKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDACGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVHCYRCEDCGGLLSEGDNQGCYPLDGHILCKTCNSARIRVLTAKASTDL", "length": 613 }, "evidence": [ { "id": "E1BMD6", "url": "https://omabrowser.org/oma/group/E1BMD6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q93052-1", "protein_name": "Lipoma-preferred partner", "gene_name": "LPP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSHPSWLPPKSTGEPLGHVPARMETTHSFGNPSISVSTQQPPKKFAPVVAPKPKYNPYKQPGGEGDFLPPPPPPLDDSSALPSISGNFPPPPPLDEEAFKVQGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRPPQSSTGSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTLKPQPAPQAGPIPVAPIGTLKPQPQPVPASYTTASTSSRPTFNVQVKSAQPSPHYMAAPSSGQIYGSGPQGYNTQPVPVSGQCPPPSTRGGMDYAYIPPPGLQPEPGYGYAPNQGRYYEGYYAAGPGYGGRNDSDPTYGQQGHPNTWKREPGYTPPGAGNQNPPGMYPVTGPKKTYITDPVSAPCAPPLQPKGGHSGQLGPSSVAPSFRPEDELEHLTKKMLYDMENPPADEYFGRCARCGENVVGEGTGCTAMDQVFHVDCFTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCNVCSKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVHCYRCEDCGGLLSEGDNQGCYPLDGHILCKTCNSARIRVLTAKASTDL", "length": 612 }, "evidence": [ { "id": "E1BMD6", "url": "https://omabrowser.org/oma/group/E1BMD6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BMD6", "url": "https://www.uniprot.org/uniprotkb/E1BMD6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BMD6", "url": "https://www.uniprot.org/uniprotkb/E1BMD6" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "E1BMD6", "url": "https://www.uniprot.org/uniprotkb/E1BMD6" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "E1BMD6", "url": "https://www.uniprot.org/uniprotkb/E1BMD6" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "E1BMD6", "url": "https://www.uniprot.org/uniprotkb/E1BMD6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BMD6", "url": "https://www.uniprot.org/uniprotkb/E1BMD6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BMD6", "url": "https://www.uniprot.org/uniprotkb/E1BMD6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BMD6", "url": "https://www.uniprot.org/uniprotkb/E1BMD6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "E1BMD6", "url": "https://www.uniprot.org/uniprotkb/E1BMD6" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "E1BMD6", "url": "https://www.uniprot.org/uniprotkb/E1BMD6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMD6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 614, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMD6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMD6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 313, "end_pos": 315 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BME0-1", "uniprot_ac": "E1BME0", "uniprot_id": "E1BME0_BOVIN", "mass": { "chemical_mass": 35783.0, "monoisotopic_mass": 35783.0 }, "refseq": { "ac": "NP_001193123", "name": "mitochondrial uncoupling protein 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193123" }, "gene_names": [ { "name": "SLC25A27", "type": "recommended", "evidence": [ { "id": "E1BME0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BME0" } ] }, { "name": "SLC25A27", "type": "synonym", "evidence": [ { "id": "NP_001193123", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193123" } ] } ], "protein_names": [ { "name": "Mitochondrial uncoupling protein 4", "type": "recommended", "evidence": [ { "id": "E1BME0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BME0/entry#names_and_taxonomy" } ] }, { "name": "mitochondrial uncoupling protein 4", "type": "synonym", "evidence": [ { "id": "NP_001193123", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193123" } ] } ], "function": [ { "annotation": "Facilitates proton transport across the inner mitochondrial membrane and may dissipate excessive proton gradient associated with oxidative and metabolic stress at neuronal synapses. Regulates glutamate-induced proton conductance in astrocytes, shifting the energy metabolism toward aerobic glycolysis and lactate transfer to neurons for ATP synthesis. Can transport chloride ions with lower efficiency. The transport mechanism remains to be elucidated.", "evidence": [ { "database": "UniProtKB", "id": "E1BME0", "url": "https://www.uniprot.org/uniprotkb/E1BME0#function" }, { "database": "UniProtKB", "id": "ARBA00053533", "url": "https://www.uniprot.org/uniprotkb/ARBA00053533#function" }, { "database": "UniProtKB", "id": "A0AAA9S8Q3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8Q3#function" }, { "database": "UniProtKB", "id": "A0AAA9TG98", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TG98#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BME0", "url": "https://www.uniprot.org/uniprotkb/E1BME0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SLC25A27", "url": "https://www.uniprot.org/uniprotkb/E1BME0", "locus": { "chromosome": "23", "start_pos": 19905207, "end_pos": 19878544, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016302", "url": "https://www.ensembl.org/id/ENSBTAG00000016302" } ] } } ], "crossref": [ { "id": "E1BME0", "url": "https://alphafold.ebi.ac.uk/entry/E1BME0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016302", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016302", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "536813", "url": "https://www.ncbi.nlm.nih.gov/gene/536813", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050391", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050391", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:536813", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536813", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FPFWKAV", "url": "https://omabrowser.org/oma/group/FPFWKAV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BME0", "url": "https://www.orthodb.org/?gene=E1BME0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45618", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45618", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-167826", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-167826", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001193123", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193123", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29823", "url": "https://www.rhea-db.org/rhea/29823", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "34979", "url": "https://www.rhea-db.org/rhea/34979", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9S8Q3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8Q3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S8Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8Q3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T9R3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T9R3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T9R3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T9R3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TG98", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TG98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TG98-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TG98-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BME0", "url": "https://www.uniprot.org/uniprotkb/E1BME0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BME0-1", "url": "https://www.uniprot.org/uniprotkb/E1BME0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTPDDAERLSPLAQRWPRACKFLLSGCAATVAELATFPLDLTKTRLQIQGEAALARLGDGATESAPYRGMVRTALGIVQEEGFLKLWQGVTPAIYRHIVYSGGRMVTYEHLREVVFGKSEDKHYPLWKSVIGGMMAGVVGQFLANPTDLVKVQMQMEGKRKLEGKPLRFRGVHHAFAKILAEGGIRGLWAGWVPNIQRAALVNMGDLTTYDTVKHYLVLNTPLEDNIVTHGLSSLCSGLVASILGTPADVIKSRIMNQPRDKQGRGLLYKSSTDCLIQAVQGEGFLSLYKGFLPSWLRMTPWSLVFWLTYEKIREMSGVSPF", "length": 323, "header": "tr|E1BME0-1|E1BME0_BOVIN Isoform 1 of Mitochondrial uncoupling protein 4 OS=Bos taurus OX=9913 GN=SLC25A27 PE=3 SV=1 CANONICAL=E1BME0-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S8Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8Q3/entry", "sequence": { "sequence": "MSTPDDAERLSPLAQRWPRACKFLLSGCAATVAELATFPLDLTKTRLQIQGEAALARLGDGATESAPYRGMVRTALGIVQEEGFLKLWQGVTPAIYRHIVYSGGRMVTYEHLREVVFGKSEDKHYPLWKSVIGGMMAGVVGQFLANPTDLVKVQMQMEGKRKLEGKPLRFRGVHHAFAKILAEGGIRGLWAGWVPNIQRAALVNMGDLTTYDTVKHYLVLNTPLEDNIVTHGLSSLCSGLVASILGTPADVIKSRIMNQPRDKQGRGLLYKSSTDCLIQAVQGEGFLSLYKGFLPSWLRMDLSVEAC", "length": 307, "header": "tr|A0AAA9S8Q3-1|A0AAA9S8Q3_BOVIN Computationally mapped isoform of Mitochondrial uncoupling protein 4 OS=Bos taurus OX=9913 GN=SLC25A27 PE=3 SV=1 CANONICAL=E1BME0-1" }, "locus": { "chromosome": "23", "start_pos": 19898750, "end_pos": 19878744, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119723.1", "url": "https://www.ensembl.org/id/ENSBTAT00000119723.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079737.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079737.1" } ] } }, { "isoform_ac": "A0AAA9T9R3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T9R3/entry", "sequence": { "sequence": "MSTPDDAERLSPLAQRWPRACKFLLSGCAATVAELATFPLDLTKTRLQIQGEAALARLGDGATESAPYRGMVRTALGIVQEEGFLKLWQGVTPAIYRHIVYSGGRMVTYEHLREVVFGKSEDKHYPLWKSVIGGMMAGVVGQFLANPTDLVKVQMQMEGKRKLEGKPLRFRGVHHAFAKILAEGGIRGLWAGWVPNIQRAALVNMGDLTTYDTVKHYLVLNTPLEDNIVTHGLSSNLIGSHKTTQ", "length": 245, "header": "tr|A0AAA9T9R3-1|A0AAA9T9R3_BOVIN Computationally mapped isoform of Solute carrier family 25 member 27 OS=Bos taurus OX=9913 GN=SLC25A27 PE=3 SV=1 CANONICAL=E1BME0-1" }, "locus": { "chromosome": "23", "start_pos": 19900759, "end_pos": 19878744, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094529.1", "url": "https://www.ensembl.org/id/ENSBTAT00000094529.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092652.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092652.1" } ] } }, { "isoform_ac": "A0AAA9TG98-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TG98/entry", "sequence": { "sequence": "MSTPDDAERLSPLAQRWPRACKFLLSGCAATVAELATFPLDLTKTRLQIQGEAALARLGDGATESAPYRGMVRTALGIVQEEGFLKLWQGVTPAIYRHIVYSGGRMVTYEHLREVVFGKSEDKHYPLWKSVIGGMMAGVVGQFLANPTDLVKVQMQMEGKRKLEGKPLRFRGVHHAFAKILAEGGIRGLWAGWVPNIQRAALVNMGDLTTYDTVKHYLVLNTPLEDNIVTHGLSSLCSGLVASILGTPADVIKSRIMNQPRDKQGRGLLYKSSTDCLIQAVQGEGFLSLYKGFLPSWLRMPQTLGISGWIATVMGKGCNCQIGELQQKLRRKRDTGADQTGCVMGMDDVEWKKVSGCCDCQQQQDPL", "length": 367, "header": "tr|A0AAA9TG98-1|A0AAA9TG98_BOVIN Computationally mapped isoform of Mitochondrial uncoupling protein 4 OS=Bos taurus OX=9913 GN=SLC25A27 PE=3 SV=1 CANONICAL=E1BME0-1" }, "locus": { "chromosome": "23", "start_pos": 19905071, "end_pos": 19878744, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104249.1", "url": "https://www.ensembl.org/id/ENSBTAT00000104249.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097202.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097202.1" } ] } }, { "isoform_ac": "E1BME0-1", "url": "https://www.uniprot.org/uniprotkb/E1BME0/entry", "sequence": { "sequence": "MSTPDDAERLSPLAQRWPRACKFLLSGCAATVAELATFPLDLTKTRLQIQGEAALARLGDGATESAPYRGMVRTALGIVQEEGFLKLWQGVTPAIYRHIVYSGGRMVTYEHLREVVFGKSEDKHYPLWKSVIGGMMAGVVGQFLANPTDLVKVQMQMEGKRKLEGKPLRFRGVHHAFAKILAEGGIRGLWAGWVPNIQRAALVNMGDLTTYDTVKHYLVLNTPLEDNIVTHGLSSLCSGLVASILGTPADVIKSRIMNQPRDKQGRGLLYKSSTDCLIQAVQGEGFLSLYKGFLPSWLRMTPWSLVFWLTYEKIREMSGVSPF", "length": 323, "header": "tr|E1BME0-1|E1BME0_BOVIN Isoform 1 of Mitochondrial uncoupling protein 4 OS=Bos taurus OX=9913 GN=SLC25A27 PE=3 SV=1 CANONICAL=E1BME0-1" }, "locus": { "chromosome": "23", "start_pos": 19900545, "end_pos": 19878744, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021691.5", "url": "https://www.ensembl.org/id/ENSBTAT00000021691.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021691.3", "url": "https://www.ensembl.org/id/ENSBTAP00000021691.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 92, "start_aa": "Thr", "end_pos": 92, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr92", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:536813", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536813", "resource": "KEGG Pathway" }, { "id": "R-BTA-167826", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-167826", "resource": "Reactome", "description": "The fatty acid cycling model" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7KFA5-1", "protein_name": "Mitochondrial uncoupling protein 4", "gene_name": "Slc25a27", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSVPEEEETLLPLTQRWPRTSKFLLSGCAATVAELATFPLDLTKTRLQMQGEAALARLGDGATESAPYRGMVRTALGIVQEEGFLKLWQGVTPAIYRHVVYSGGRMVTYEHLREVVFGKSEDKHYPLWKSVIGGMMAGVIGQFLANPTDLVKVQMQMEGKRKLEGKPLRFRGVHHAFAKILAEGGIRGLWAGWVPNIQRAALVNMGDLTTYDTVKHYLVLNTPLEENIATHGLSSLCSGLVASILGTPADVIKSRIMNQPRDKQGRGLLYKSSTDCLIQAVQGEGFLSLYKGFLPSWLRMEDTLLHRNCNLQGAALSISMKTKFSLTPLFF", "length": 331 }, "evidence": [ { "id": "E1BME0", "url": "https://omabrowser.org/oma/group/E1BME0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LSK2-1", "protein_name": "Mitochondrial uncoupling protein 4", "gene_name": "SLC25A27", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSAPEDEERLLPLAQRWPRASKFLLSGCAATVAELATFPLDLTKTRLQIQGEAALARLGHGAREAAPYRGMVRTALGIVQEEGFLKLWQGVTPAIYRHIVYSGGRMVTYEHLREVVFGKGEDKHYPLWKSVIGGMMAGVVGQFLANPTDLVKVQMQMEGKRKLEGKPLRFRGVHHAFAKILAEGGVRGLWAGWVPNIQRAALVNMGDLTTYDTVKHYLVLNTPLEDNIMTHGLSSLCSGLVASILGTPADVIKSRIMNQPRDKQGRGLLYKSSTDCLVQAVQGEGFMSLYKGFLPSWLRMTPWSLVFWLTYEKIREMSGVSPF", "length": 323 }, "evidence": [ { "id": "E1BME0", "url": "https://omabrowser.org/oma/group/E1BME0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O95847-1", "protein_name": "Mitochondrial uncoupling protein 4", "gene_name": "SLC25A27", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVPEEEERLLPLTQRWPRASKFLLSGCAATVAELATFPLDLTKTRLQMQGEAALARLGDGARESAPYRGMVRTALGIIEEEGFLKLWQGVTPAIYRHVVYSGGRMVTYEHLREVVFGKSEDEHYPLWKSVIGGMMAGVIGQFLANPTDLVKVQMQMEGKRKLEGKPLRFRGVHHAFAKILAEGGIRGLWAGWVPNIQRAALVNMGDLTTYDTVKHYLVLNTPLEDNIMTHGLSSLCSGLVASILGTPADVIKSRIMNQPRDKQGRGLLYKSSTDCLIQAVQGEGFMSLYKGFLPSWLRMTPWSMVFWLTYEKIREMSGVSPF", "length": 323 }, "evidence": [ { "id": "E1BME0", "url": "https://omabrowser.org/oma/group/E1BME0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D6D0-1", "protein_name": "Mitochondrial uncoupling protein 4", "gene_name": "Slc25a27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPIAEEEKLLPLTQRWPRTSKFLLSGCAATVAELATFPLDLTKTRLQMQGEAALARLGDGAVDSAPYRGMVRTALGIVQEEGFLKLWQGVTPAIYRHVVYSGGRMVTYEHLREVVFGKSEDKHYPLWKSVIGGMMAGVIGQFLANPTDLVKVQMQMEGKRRLEGKPLRFRGVHHAFAKILAEGGIRGLWAGWIPNIQRAALVNMGDLTTYDTVKHYLVLNTPLEDNISTHGLSSLCSGLVASILGTPADVIKSRIMNQPRDKQGRGLLYKSSADCLIQAVQGEGFLSLYKGFLPSWLRMTPWSMVFWLTYEKIREMSGVSPF", "length": 322 }, "evidence": [ { "id": "E1BME0", "url": "https://omabrowser.org/oma/group/E1BME0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VX14-1", "protein_name": "Uncoupling protein 4A, isoform B", "gene_name": "Ucp4A", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAAKTDESSPAVASSTSSNPAPSSGRHQLRPVKFDYADSFACTYIVSVVAASIAELATYPLDLTKTRLQIQGEGAAHSAGKSNMQYRGMVATAFGIAREEGALKLWQGVTPALYRHVVYSGVRICSYDLMRKEFTQNGTQALPVWKSALCGVTAGAVAQWLASPADLVKVQIQMEGRRRLMGEPPRVHSAGHAFRQIVQRGGIKGLWKGSIPNVQRAALVNLGDLTTYDTIKHLIMNRLQMPDCHTVHVLASVCAGFVAAIMGTPADVVKTRIMNQPTDENGRGLLYRGSVDCLRQTVSKEGFVALYKGFLPCWIRMAPWSLTFWLSFEQIRKMIGASGY", "length": 340 }, "evidence": [ { "id": "E1BME0", "url": "https://omabrowser.org/oma/group/E1BME0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9XI74-1", "protein_name": "Mitochondrial uncoupling protein 3", "gene_name": "PUMP3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MERSRVTREAPTGTRILLASLSAMVAESVTFPIDLTKTRMQLHGSGSASGAHRIGAFGVVSEIARKEGVIGLYKGLSPAIIRHLFYTPIRIIGYENLKGLIVRSETNNSESLPLATKALVGGFSGVIAQVVASPADLVKVRMQADGRLVSQGLKPRYSGPIEAFTKILQSEGVKGLWKGVLPNIQRAFLVNMGELACYDHAKHFVIDKKIAEDNIFAHTLASIMSGLASTSLSCPADVVKTRMMNQGENAVYRNSYDCLVKTVKFEGIRALWKGFFPTWARLGPWQFVFWVSYEKFRLLAGISSF", "length": 305 }, "evidence": [ { "id": "E1BME0", "url": "https://omabrowser.org/oma/group/E1BME0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "E1BME0", "url": "https://www.uniprot.org/uniprotkb/E1BME0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "response to cold", "id": "GO:0009409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009409", "evidence": [ { "database": "UniProtKB", "id": "E1BME0", "url": "https://www.uniprot.org/uniprotkb/E1BME0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "E1BME0", "url": "https://www.uniprot.org/uniprotkb/E1BME0" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "E1BME0", "url": "https://www.uniprot.org/uniprotkb/E1BME0" } ], "pmid": "" }, { "name": "proton transmembrane transporter activity", "id": "GO:0015078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015078", "evidence": [ { "database": "UniProtKB", "id": "E1BME0", "url": "https://www.uniprot.org/uniprotkb/E1BME0" } ], "pmid": "" }, { "name": "chloride transmembrane transporter activity", "id": "GO:0015108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015108", "evidence": [ { "database": "UniProtKB", "id": "E1BME0", "url": "https://www.uniprot.org/uniprotkb/E1BME0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29823", "name": "", "equation": "chloride(in) = chloride(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MN01-1", "Q5E9B7-1", "Q9XSA7-1", "P35071-1", "P35526-1" ], "evidence": [ { "id": "29823", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29823" } ] }, { "id": "34979", "name": "", "equation": "H(+)(in) = H(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "34979", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/34979" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "F1MN01", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] } ] }, { "uniprot_ac": "P35071", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "P35071", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35071" } ] } ] }, { "uniprot_ac": "P35526", "gene_name": "CLIC5", "activity": [ { "ec_number": "1.8.-.-", "activity": "", "evidence": [ { "id": "P35526", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35526" } ] } ] }, { "uniprot_ac": "Q5E9B7", "gene_name": "CLIC1", "activity": [ { "ec_number": "1.8.-.-", "activity": "", "evidence": [ { "id": "Q5E9B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9B7" } ] }, { "ec_number": "1.8.5.1", "activity": "L-dehydroascorbate + 2 glutathione = glutathione disulfide + L-ascorbate.", "evidence": [ { "id": "Q5E9B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9B7" } ] } ] }, { "uniprot_ac": "Q9XSA7", "gene_name": "CLIC4", "activity": [ { "ec_number": "1.8.-.-", "activity": "", "evidence": [ { "id": "Q9XSA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XSA7" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BME0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 323, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BME0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BME0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 92 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"length": 278, "header": "tr|E1BMH7-1|E1BMH7_BOVIN Isoform 1 of Coiled-coil domain containing 198 OS=Bos taurus OX=9913 GN=CCDC198 PE=4 SV=4 CANONICAL=E1BMH7-1" }, "isoforms": [ { "isoform_ac": "E1BMH7-1", "url": "https://www.uniprot.org/uniprotkb/E1BMH7/entry", "sequence": { "sequence": "MGLSHSKPHPRVTKVVPLQNKEEETPLAGPVDFAFTQNLEENSLYSFARLQDRNKALEGQLPPLRETWYGRYSEGPRAMYFDFPLEQQETSIIKRHPPRRLQKLEPIDLPQVITSERLLNQQEARRTHKAKQELEKKMQTLMYPSGKRQYLHKMQMLEMNRKRQEAQVELKKSLHKEPRTNKQKQRDHKAKKILQSIPRNDDGDFLTLLPDETLSRSLGNTQNADFLEHQARNDHCPRKIGKMEIWLREQEARGELLWDSSSSDSDESGKVEKKKEHW", "length": 278, "header": "tr|E1BMH7-1|E1BMH7_BOVIN Isoform 1 of Coiled-coil domain containing 198 OS=Bos taurus OX=9913 GN=CCDC198 PE=4 SV=4 CANONICAL=E1BMH7-1" }, "locus": { "chromosome": "10", "start_pos": 69853174, "end_pos": 69824357, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000043680.5", "url": "https://www.ensembl.org/id/ENSBTAT00000043680.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000041234.5", "url": "https://www.ensembl.org/id/ENSBTAP00000041234.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BMH7", "url": "https://www.uniprot.org/uniprotkb/E1BMH7" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "E1BMH7", "url": "https://www.uniprot.org/uniprotkb/E1BMH7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "energy homeostasis", "id": "GO:0097009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097009", "evidence": [ { "database": "UniProtKB", "id": "E1BMH7", "url": "https://www.uniprot.org/uniprotkb/E1BMH7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMH7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 278, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMH7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMH7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BMJ6-1", "uniprot_ac": "E1BMJ6", "uniprot_id": "E1BMJ6_BOVIN", "mass": { "chemical_mass": 79159.0, "monoisotopic_mass": 79159.0 }, "refseq": { "ac": "XP_024852099", "name": "uncharacterized protein KIAA1958 homolog isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852099" }, "gene_names": [ { "name": "KIAA1958", "type": "recommended", "evidence": [ { "id": "E1BMJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMJ6" } ] }, { "name": "KIAA1958", "type": "synonym", "evidence": [ { "id": "XP_024852099", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852099" } ] } ], "protein_names": [ { "name": "KIAA1958", "type": "synonym", "evidence": [ { "id": "E1BMJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMJ6/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein KIAA1958 homolog isoform X2", "type": "synonym", "evidence": [ { "id": "XP_024852099", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852099" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMJ6", "url": "https://www.uniprot.org/uniprotkb/E1BMJ6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KIAA1958", "url": "https://www.uniprot.org/uniprotkb/E1BMJ6", "locus": { "chromosome": "8", "start_pos": 101939600, "end_pos": 101814482, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016259", "url": "https://www.ensembl.org/id/ENSBTAG00000016259" } ] } } ], "crossref": [ { "id": "E1BMJ6", "url": "https://alphafold.ebi.ac.uk/entry/E1BMJ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016259", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016259", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "509630", "url": "https://www.ncbi.nlm.nih.gov/gene/509630", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021893", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021893", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042838", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042838", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:509630", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509630", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YWCVTNG", "url": "https://omabrowser.org/oma/group/YWCVTNG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MM73", "url": "https://www.orthodb.org/?gene=A0A3Q1MM73", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BMJ6", "url": "https://www.orthodb.org/?gene=E1BMJ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46963", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46963", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46963:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46963:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12012", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12012", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024852099", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852099", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MM73", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MM73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MM73-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MM73-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMJ6", "url": "https://www.uniprot.org/uniprotkb/E1BMJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMJ6-1", "url": "https://www.uniprot.org/uniprotkb/E1BMJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDCLHTSSENLSKLVSWAHSHGTICSLIPNLKHLLSEGSHGNLTAMWGCSAGHAYHWPLTATCRAGSQERVCFQDNRSFNSDSPSIIGVPSETQTSPVERYPGRPVKTKLDCNRTRDSCDFSYCSEPSELDEAVEEYEDENTLFDMVCESSVTDEDSDFEPQPQRPQSIARKRPGIVPSSLHSSSQTQMIDECSSDVIIKKIKQEIPEDYYIVANAELTGGVDGPALSLTQMAKPKSQTHAGPSLGSAKLISHVTSAISSELDPHGVSASPSVMSRPVVQKTTRVSLASPNRGPPSSHGTSQHVAMQMPVSTSHPNKQISIPLSALQLPGQDEQVASEEFLSHLPSQVSSCEVALSPSVNTEPEVSSSQQQPPVAPTITTEATAQCIPAYSTKLNKFPVFNINDDLNDLCTSAVSPNTTKATRYALNVWRYWCMTNGLKDHTDITKIPAVKLNELLENFYVTVKKSDGSDFLATSLHAIRRGLDRILKNAGVGFSITSSTFSSSTKKLKEKLWVLSKAGMSGARSRNIVYFSVSDEEEMWQTGCLGDDSPITLLSTVVKYNSQYLNMRTLQEHADLMYGDIELLTDPQNHSYFARTDSVKRESRSASTRVCHGKIYHEHSRGHKQCPYCLLYKYMYVHRPPTQMEAKSPFYLTARKEAADMGRVWYEEQRMGLRSLRGVVPNLAKKVKLENCENFTFVSFTQVSRRLSSHSCCQ", "length": 715, "header": "tr|E1BMJ6-1|E1BMJ6_BOVIN Isoform 1 of KIAA1958 OS=Bos taurus OX=9913 GN=KIAA1958 PE=4 SV=1 CANONICAL=E1BMJ6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MM73-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MM73/entry", "sequence": { "sequence": "MEDCLHTSSENLSKLVSWAHSHGTICSLIPNLKHLLSEGSHGNLTAMWGCSAGHAYHWPLTATCRAGSQERVCFQDNRSFNSDSPSIIGVPSETQTSPVERYPGRPVKTKLDCNRTRDSCDFSYCSEPSELDEAVEEYEDENTLFDMVCESSVTDEDSDFEPQPQRPQSIARKRPGIVPSSLHSSSQTQMIDECSSDVIIKKIKQEIPEDYYIVANAELTGGVDGPALSLTQMAKPKSQTHAGPSLGSAKLISHVTSAISSELDPHGVSASPSVMSRPVVQKTTRVSLASPNRGPPSSHGTSQHVAMQMPVSTSHPNKQISIPLSALQLPGQDEQVASEEFLSHLPSQVSSCEVALSPSVNTEPEVSSSQQQPPVAPTITTEATAQCIPDQDERAAELSREQNEKTIRSTQTALRNFREFLISKYPSETREIYVIPCKELDAYLASFFVDARQKDGSEYEPNSLANYQCGLERYLKEHRYGYSITRDKEFKRSQEALKQKQIELRCKGKGNKPHKSMKLTFADELILRKRGLLSRYNPEGLLNLVWLNNTKAFGHCTGFHGSTLKWGDIRLRVTETGLEYLEWMGQDTGDLNAKTKRGGTDSRVYATQHAPQTCPVQDYKEYAQRRPPAMRYEDAPFYLSIKPVVNLAALHWYNCQALGKNKLAKMVKTMCEKGNIPGRKTNFSVYQSCSTLSEAQSNQLVLICNNLSQQAAQSVAGHSSSGNFIVSASYDSSSDTA", "length": 737, "header": "tr|A0A3Q1MM73-1|A0A3Q1MM73_BOVIN Computationally mapped isoform of KIAA1958 OS=Bos taurus OX=9913 GN=KIAA1958 PE=4 SV=1 CANONICAL=E1BMJ6-1" }, "locus": { "chromosome": "8", "start_pos": 101905669, "end_pos": 101872500, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078712.2", "url": "https://www.ensembl.org/id/ENSBTAT00000078712.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070483.1", "url": "https://www.ensembl.org/id/ENSBTAP00000070483.1" } ] } }, { "isoform_ac": "E1BMJ6-1", "url": "https://www.uniprot.org/uniprotkb/E1BMJ6/entry", "sequence": { "sequence": "MEDCLHTSSENLSKLVSWAHSHGTICSLIPNLKHLLSEGSHGNLTAMWGCSAGHAYHWPLTATCRAGSQERVCFQDNRSFNSDSPSIIGVPSETQTSPVERYPGRPVKTKLDCNRTRDSCDFSYCSEPSELDEAVEEYEDENTLFDMVCESSVTDEDSDFEPQPQRPQSIARKRPGIVPSSLHSSSQTQMIDECSSDVIIKKIKQEIPEDYYIVANAELTGGVDGPALSLTQMAKPKSQTHAGPSLGSAKLISHVTSAISSELDPHGVSASPSVMSRPVVQKTTRVSLASPNRGPPSSHGTSQHVAMQMPVSTSHPNKQISIPLSALQLPGQDEQVASEEFLSHLPSQVSSCEVALSPSVNTEPEVSSSQQQPPVAPTITTEATAQCIPAYSTKLNKFPVFNINDDLNDLCTSAVSPNTTKATRYALNVWRYWCMTNGLKDHTDITKIPAVKLNELLENFYVTVKKSDGSDFLATSLHAIRRGLDRILKNAGVGFSITSSTFSSSTKKLKEKLWVLSKAGMSGARSRNIVYFSVSDEEEMWQTGCLGDDSPITLLSTVVKYNSQYLNMRTLQEHADLMYGDIELLTDPQNHSYFARTDSVKRESRSASTRVCHGKIYHEHSRGHKQCPYCLLYKYMYVHRPPTQMEAKSPFYLTARKEAADMGRVWYEEQRMGLRSLRGVVPNLAKKVKLENCENFTFVSFTQVSRRLSSHSCCQ", "length": 715, "header": "tr|E1BMJ6-1|E1BMJ6_BOVIN Isoform 1 of KIAA1958 OS=Bos taurus OX=9913 GN=KIAA1958 PE=4 SV=1 CANONICAL=E1BMJ6-1" }, "locus": { "chromosome": "8", "start_pos": 101938596, "end_pos": 101872500, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021628.5", "url": "https://www.ensembl.org/id/ENSBTAT00000021628.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021628.2", "url": "https://www.ensembl.org/id/ENSBTAP00000021628.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:509630", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509630", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7JGB5-1", "protein_name": "Uncharacterized protein KIAA1958 homolog isoform X4", "gene_name": "Kiaa1958", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEDCLHTSSENLSKLVSWAHSHGTICSLIPNLKHLLSEGSHGNLTAMWGCSAGHAYHWPLTATCRAGSQERVCFQDNRSFNSDSPSIIGVPSETQTSPVERYPGRPVKAKLDCNRTRDSCDFSYCSEPSELDEAVEEYEDENTLFDMVCESSVTDEDSDFEPQTQRPQSIARKRPGIVPSSIHSGSQGQMVDECSNDVIIKKIKQEIPEDYYIVANAELTGGVDGPALSLTQMAKPKLQTHAGPSCVGSAKLIPHVTSAISAELDPHIMSASPSVISRPIIPKTARVSLASPNRGPPGAHGTAHQVTMQMPVSTSHPNKQISIPLSALQLPGQDEQVVSEEFLPHLPSQVSSCEVALSPSVNTEPEVSSSQQQPPIAPTITTEATAQCIPDQDERAAELSREQNEKTIRSTQTALRNFPYSTKLNKFPVFNINDDLNDLCTSAVSPNTTKATRYALNVWRYWCMTNGLKDHTDITKIPAVKLNELLENFYVTVKKSDGSDFLATSLHAIRRGLDRILKNAGVGFSITSSTFSSSTKKLKEKLWVLSKAGMSGARSRNIVYFSLSDEEEMWQAGCLGDDSPITLLSTVVKYNSQYLNMRTLQEHADLMYGDIELLKDPQNQPYFARTDSVKRESRSGSTRVCHGKIYHEHSRGHKQCPYCLLYKYMYIHRPPTQMDAKSPFYLTARKEATDMGNVWYEEQRMGLRSLRGIVPNLARKVKLDNCENFTFVSFTQVSRRLSSHSCCQ", "length": 744 }, "evidence": [ { "id": "E1BMJ6", "url": "https://omabrowser.org/oma/group/E1BMJ6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1SNA7-1", "protein_name": "KIAA1958", "gene_name": "KIAA1958", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEDCLHTSSENLSKLVSWAHSHGTICSLIPNLKHLLSEGSHGNLTAMWGCSAGHAYHWPLTATCRAGSQERVCFQDNRSFNSDSPSIIGVPSETQTSPVERYPGRPVKAKLDCNRTRDSCDFSYCSEPSELDEAVEEYEDENTLFDMVCESSVTDEDSDFEPQTQRPQSITRKRPGIVPSSLHSSSQAQMIDECSSDVIIKKIKQEIPEDYYIVANAELTGGVDGPALSLTQMAKPKPQTHAGPSCIGSAKLIPHVTSAISTELDPHGMSASPSVMSRPIIQKTARVSLASPNRGPPGAHGTNQQVAMQMPVSTSHPNKQISIPLSALQLPGQDEQVASEEFLSHLPSQVSSCEVALSPSVNTEPEVSSSQQQPPVAPTITTEATAQCIPAYSTKLNKFPVFNINDDLNDLCTSAVSPNTTKATRYALNVWRYWCMTNGLKDHTDITKIPAVKLNELLENFYVTVKKSDGSDFLATSLHAIRRGLDRILKNAGVGFSITSSTFSSSTKKLKEKLWVLSKAGMSGARSRNIVYFSLSDEEEMWQAGCLGDDSPITLLSTVVKYNSQYLNMRTLQEHADLMYGDIELLKDPQNQPYFARTDSVKRESRSGSTRVCHGKIYHEHSRGHKQCPYCLLYKYMYIHRPPTQMDAKSPFYLTARKEATDLGSVWYEDQRMGLRSLRGIVPNLAKKVKLENCENFTFVSFTQVSRRLGSHSCCQ", "length": 716 }, "evidence": [ { "id": "E1BMJ6", "url": "https://omabrowser.org/oma/group/E1BMJ6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8C4P0-1", "protein_name": "Uncharacterized protein KIAA1958 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDCLHTSSENLSKLVSWAHSHGTICSLIPNLKHLLSEGSHGNLTAMWGCSAGHAYHWPLTATCRAGSQERVCFQDNRSFNSDSPSIIGVPSETQTSPVERYPGRPVKAKLDCNRTRDSCDFSYCSEPSELDEAVEEYEDENTLFDMVCESSVTDEDSDFEPQTQRPQSIARKRPGIVPSSIHSSSQGQMVDECSNDVIIKKIKQEIPEDYYIVANAELTGGVDGPALSLTQMAKPKPQTHAGPSCVGSAKLIPHVTSAINTELDPHILSASPSVISRPIIPKTARVSLASPNRGPPGAHGTAHQVTMQMPVSTSHPNKQISIPLSALQLPGQDEQVASEEFLPHLPSQVSSCEVALSPSVNTEPEVSSSQQQPPAAPTITTEATAQCIPAYSTKLNKFPVFNINDDLNGLCTSAVSPNTTKATRYALNVWRYWCMTNGLKDHTDITKIPAVKLNELLENFYVTVKKSDGSDFLATSLHAIRRGLDRILKNAGVGFSITSSTFSSSTKKLKEKLWVLSKAGMSGARSRNIVYFSLSDEEEMWQAGCLGDDSPITLLSTVVKYNSQYLNMRTLQEHADLMYGDIELLKDPQNQPYFARTDSVKRESRSGSTRVCHGKIYHEHSRGHKQCPYCLLYKYMYIHRPPTQMEAKSPFYLTARKEATDMGSVWYEEQRMGLRSLRGIVPNLARKVKLENCENFTFVSFTQVSRRLGSHSCCQ", "length": 716 }, "evidence": [ { "id": "E1BMJ6", "url": "https://omabrowser.org/oma/group/E1BMJ6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N8K9-1", "protein_name": "Uncharacterized protein KIAA1958", "gene_name": "KIAA1958", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDCLHTSSENLSKLVSWAHSHGTICSLIPNLKHLLSEGSHGNLTAMWGCSAGHAYHWPLTATCRAGSQERVCFQDNRSFNSDSPSIIGVPSETQTSPVERYPGRPVKAKLDCNRTRDSCDFSYCSEPSELDETVEEYEDENTLFDMVCESSVTDEDSDFEPQTQRPQSIARKRPGVVPSSLHSSSQTQMVDECSNDVIIKKIKQEIPEDYYIVANAELTGGVDGPALSLTQMAKPKPQTHAGPSCVGSAKLIPHVTSAISTELDPHGMSASPSVISRPIVQKTARVSLASPNRGPPGTHGTNQQVAMQMPVSTSHPNKQISIPLSALQLPGQDEQVASEEFLSHLPSQVSSCEVALSPSVNTEPEVSSSQQQPPVAPAITTEATAQCIPAYSTKLNKFPVFNINDDLNDLCTSAVSPNTTKATRYALNVWRYWCMTNGLKDHTDITKIPAVKLNELLENFYVTVKKSDGSDFLATSLHAIRRGLDRILKNAGVGFSITSSTFSSSTKKLKEKLWVLSKAGMSGARSRNIVYFSLSDEEEMWQAGCLGDDSPITLLSTVVKYNSQYLNMRTLQEHADLMYGDIELLKDPQNQPYFARTDSVKRESRSGSTRVCHGKIYHEHSRGHKQCPYCLLYKYMYIHRPPTQMEAKSPFYLTARKEATDMGSVWYEEQRMGLRSLRGIVPNLAKKVKLENCENFTFVSFTQVSRRLGSHSCCQ", "length": 716 }, "evidence": [ { "id": "E1BMJ6", "url": "https://omabrowser.org/oma/group/E1BMJ6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 418, "end_pos": 420, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" }, { "start_pos": 590, "end_pos": 592, "annotation": "n_glycosylation_sequon" }, { "start_pos": 695, "end_pos": 697, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMJ6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 715, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMJ6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMJ6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BMJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMJ6" }, { "id": "PF12012", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12012" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ZMYM2-like/QRICH1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 531, "end_pos": 684, "start_aa": "Tyr", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 114, "end_pos": 116 }, { "start_pos": 11, "end_pos": 13 }, { "start_pos": 418, "end_pos": 420 }, { "start_pos": 43, "end_pos": 45 }, { "start_pos": 590, "end_pos": 592 }, { "start_pos": 695, "end_pos": 697 }, { "start_pos": 77, "end_pos": 79 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BMM4-1", "uniprot_ac": "E1BMM4", "uniprot_id": "E1BMM4_BOVIN", "mass": { "chemical_mass": 38932.0, "monoisotopic_mass": 38932.0 }, "refseq": { "ac": "NP_001179887", "name": "vacuolar protein sorting-associated protein 26B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179887" }, "gene_names": [ { "name": "VPS26B", "type": "recommended", "evidence": [ { "id": "E1BMM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMM4" } ] }, { "name": "VPS26B", "type": "synonym", "evidence": [ { "id": "NP_001179887", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179887" } ] } ], "protein_names": [ { "name": "VPS26, retromer complex component B", "type": "synonym", "evidence": [ { "id": "E1BMM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMM4/entry#names_and_taxonomy" } ] }, { "name": "vacuolar protein sorting 26 homolog B", "type": "synonym", "evidence": [ { "id": "NP_001179887", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179887" } ] }, { "name": "vacuolar protein sorting-associated protein 26B", "type": "synonym", "evidence": [ { "id": "NP_001179887", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179887" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMM4", "url": "https://www.uniprot.org/uniprotkb/E1BMM4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "VPS26B", "url": "https://www.uniprot.org/uniprotkb/E1BMM4", "locus": { "chromosome": "15", "start_pos": 83525464, "end_pos": 83503707, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014838", "url": "https://www.ensembl.org/id/ENSBTAG00000014838" } ] } } ], "crossref": [ { "id": "E1BMM4", "url": "https://alphafold.ebi.ac.uk/entry/E1BMM4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014838", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014838", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "614321", "url": "https://www.ncbi.nlm.nih.gov/gene/614321", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR014752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028934", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028934", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:614321", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614321", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FKWKFSS", "url": "https://omabrowser.org/oma/group/FKWKFSS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MSA5", "url": "https://www.orthodb.org/?gene=A0A3Q1MSA5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BMM4", "url": "https://www.orthodb.org/?gene=E1BMM4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12233", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12233", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179887", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179887", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MSA5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MSA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MSA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MSA5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S6K1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6K1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S6K1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6K1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMM4", "url": "https://www.uniprot.org/uniprotkb/E1BMM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMM4-1", "url": "https://www.uniprot.org/uniprotkb/E1BMM4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFFGFGQSVDVDILLNDADSRRRAEHKTEDGKKDKYFLFYDGETVSGKVSLALKNPNKRLEHQGIKVEFIGQIELYYDRGNHHEFVSLVKDLARPGEVTQSQAFDFEFTHVEKPYESYTGQNVKLRYFLRATISRRLNDVVKEMDIVVHTLSTYPELNSSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIKHMEIDIIKRETTGTGPNVYHENDTIAKYEIMDGAPVRGESIPIRLFLAGYELTPTMRDINKKFSVRYYLNLVLIDDEERRYFKQQEVVLWRKGDIVRKSMSHQAAIASQRFEGTTPLGEARTPGPLSDSGNRQ", "length": 336, "header": "tr|E1BMM4-1|E1BMM4_BOVIN Isoform 1 of VPS26, retromer complex component B OS=Bos taurus OX=9913 GN=VPS26B PE=3 SV=3 CANONICAL=E1BMM4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MSA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MSA5/entry", "sequence": { "sequence": "MSFFGFGQSVDVDILLNDADSRRRAEHKTEDGKKDKYFLFYDGETVSGKVSLALKNPNKRLEHQGIKVEFIGQIELYYDRGNHHEFVSLVKDLARPGEVTQSQAFDFEFTHVEKPYESYTGQNVKLRYFLRATISRRLNDVVKEMDIVVHTLSTYPELNSSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIKHMEIDIIKRETTGTGPNVYHENDTIAKYEIMDGAPVRGESIPIRLFLAGYELTPTMRDINKKFSVRYYLNLVLIDDEERRYFKQQEVVLWRKGDIVRKSMSHQAAIASQRFEGTTPLGEARTPGPLSDSGNRQLRIKSNSSAEKGTKRKN", "length": 353, "header": "tr|A0A3Q1MSA5-1|A0A3Q1MSA5_BOVIN Computationally mapped isoform of VPS26, retromer complex component B OS=Bos taurus OX=9913 GN=VPS26B PE=3 SV=1 CANONICAL=E1BMM4-1" }, "locus": { "chromosome": "15", "start_pos": 83521016, "end_pos": 83503919, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068622.3", "url": "https://www.ensembl.org/id/ENSBTAT00000068622.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072867.1", "url": "https://www.ensembl.org/id/ENSBTAP00000072867.1" } ] } }, { "isoform_ac": "A0AAA9S6K1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6K1/entry", "sequence": { "sequence": "MSFFGFGQSVDVDILLNDADSRRRAEHKTEDGKKDKYFLFYDGETVSGKVSLALKNPNKRLEHQGIKVEFIGQIELYYDRGNHHEFVSLVKDLARPGEVTQSQAFDFEFTHVEKPYESYTGQNVKLRYFLRATISRRLNDVVKEMDIVVHTLSTYPELNSSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIKHMEIDIIKRETTGTGPNVYHENDTIAKYEIMDGAPVRGESIPIRLFLAGYELTPTMRDINKKFSVRYYLNLVLIDDEERRYFKQQEVVLWRKGDIVRKSMSHQAAIASQRFEGTTPLGEARTPGPLSDSGNRQCSEKMDKTTTEESAGMDETFALQRRKCA", "length": 364, "header": "tr|A0AAA9S6K1-1|A0AAA9S6K1_BOVIN Computationally mapped isoform of VPS26, retromer complex component B OS=Bos taurus OX=9913 GN=VPS26B PE=3 SV=1 CANONICAL=E1BMM4-1" }, "locus": { "chromosome": "15", "start_pos": 83524460, "end_pos": 83503919, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128472.2", "url": "https://www.ensembl.org/id/ENSBTAT00000128472.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077784.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077784.1" } ] } }, { "isoform_ac": "E1BMM4-1", "url": "https://www.uniprot.org/uniprotkb/E1BMM4/entry", "sequence": { "sequence": "MSFFGFGQSVDVDILLNDADSRRRAEHKTEDGKKDKYFLFYDGETVSGKVSLALKNPNKRLEHQGIKVEFIGQIELYYDRGNHHEFVSLVKDLARPGEVTQSQAFDFEFTHVEKPYESYTGQNVKLRYFLRATISRRLNDVVKEMDIVVHTLSTYPELNSSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIKHMEIDIIKRETTGTGPNVYHENDTIAKYEIMDGAPVRGESIPIRLFLAGYELTPTMRDINKKFSVRYYLNLVLIDDEERRYFKQQEVVLWRKGDIVRKSMSHQAAIASQRFEGTTPLGEARTPGPLSDSGNRQ", "length": 336, "header": "tr|E1BMM4-1|E1BMM4_BOVIN Isoform 1 of VPS26, retromer complex component B OS=Bos taurus OX=9913 GN=VPS26B PE=3 SV=3 CANONICAL=E1BMM4-1" }, "locus": { "chromosome": "15", "start_pos": 83519135, "end_pos": 83503919, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019761.5", "url": "https://www.ensembl.org/id/ENSBTAT00000019761.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019761.5", "url": "https://www.ensembl.org/id/ENSBTAP00000019761.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:614321", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614321", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B1WBS4-1", "protein_name": "VPS26 retromer complex component B", "gene_name": "Vps26b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSFFGFGQSVEVEILLNDAESRKRAEHKTEDGKKEKYFLFYDGETVSGKVSLSLKNPNKRLEHQGIKIEFIGQIELYYDRGNHHEFVSLVKDLARPGEITQSQAFDFEFTHVEKPYESYTGQNVKLRYFLRATISRRLNDVVKEMDIVVHTLSTYPELNSSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIKHMEIDIIKRETTGTGPNVYHENDTIAKYEIMDGAPVRGESIPIRLFLAGYELTPTMRDINKKFSVRYYLNLVLIDEEERRYFKQQEVVLWRKGDIVRKSMSHQAAIASQRFEGTTSLGEVRTPGQLSDNNSRQ", "length": 336 }, "evidence": [ { "id": "E1BMM4", "url": "https://omabrowser.org/oma/group/E1BMM4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1NPH4-1", "protein_name": "VPS26 retromer complex component B", "gene_name": "VPS26B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSFFGFGQSAEVELVLSDAESRRRVEHKTEEGKKEKYFLFYDGETVSGRVILTLKHPNRRLEHQGIKVEFIGQIELYYDRGNHHEFVSLVKDLARPGEFTQSQIFDFEFTHVEKPYESYTGQNVKLRYFLRATVSRRLNDVVKEMDIVVHTLSTYPELNSSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIKHMEIDIIKRETTGTGPNVYHENDTIAKYEIMDGAPVRGESIPIRLFLAGYELTPTMRDINKKFSVRYYLNLVLIDEEERRYFKQQEVVLWRKGDIVRKSMSHQAAIASQRFEGTSSHTEAKTPSQPAENNGRQ", "length": 336 }, "evidence": [ { "id": "E1BMM4", "url": "https://omabrowser.org/oma/group/E1BMM4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3GTV9-1", "protein_name": "Vacuolar protein sorting-associated protein 26B", "gene_name": "Vps26b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSFFGFGQSVEVEILLNDAESRKRAEHKTEDGKKEKYFLFYDGETVSGKVSLSLKNPNKRLEHQGIKIEFIGQIELYYDRGNHHEFVSLVKDLARPGEITQSQAFDFEFTHVEKPYESYTGQNVKLRYFLRATISRRLNDVVKEMDIVVHTLSTYPELNSSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIKHMEIDIIKRETTGTGPNVYHENDTIAKYEIMDGAPVRGESIPIRLFLAGYELTPTMRDINKKFSVRYYLNLVLIDEEERRYFKQQEVVLWRKGDIVRKSMSHQAAIASQRFEGTTSLGEVRTPGPLSDNNSRQ", "length": 336 }, "evidence": [ { "id": "E1BMM4", "url": "https://omabrowser.org/oma/group/E1BMM4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P40335-1", "protein_name": "Carboxypeptidase Y-deficient protein 8", "gene_name": "PEP8", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSIFFKPPIDIEILFDNEESRKHVDIATRSSNSSYKSMKESLPVYEDGESLGGIVTLRVRDSKKVDHLGIKVSVIGSIDMLKSHGSGNSSSKKVTSSTSSSSSNGSVDVRKNSVDQFLCQSYDLCPAGELQHSQSFPFLFRDLSKRYESYKGKNVDVAYYVKVTVMRKSTDISKIKRFWVYLYNSVTTAPNTLSANETKATTNDIAGGNYAADNASDNTQTKSTQGEAADVNQVLPISHSNNEPKPVRLDIGIENCLHIEFEYAKSQYSLKEVIVGRIYFLLTRLRIKHMELSLITRESSGLQTSNVMTDSTAIRYEIMDGSSVKGETIPIRLFLSGYDLTPNMSCNYFNVKNYLSLVIIDEDGRRYFKQSEITLYRTR", "length": 379 }, "evidence": [ { "id": "E1BMM4", "url": "https://omabrowser.org/oma/group/E1BMM4/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q4G0F5-1", "protein_name": "Vacuolar protein sorting-associated protein 26B", "gene_name": "VPS26B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSFFGFGQSVEVEILLNDAESRKRAEHKTEDGKKEKYFLFYDGETVSGKVSLALKNPNKRLEHQGIKIEFIGQIELYYDRGNHHEFVSLVKDLARPGEITQSQAFDFEFTHVEKPYESYTGQNVKLRYFLRATISRRLNDVVKEMDIVVHTLSTYPELNSSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIKHMEIDIIKRETTGTGPNVYHENDTIAKYEIMDGAPVRGESIPIRLFLAGYELTPTMRDINKKFSVRYYLNLVLIDEEERRYFKQQEVVLWRKGDIVRKSMSHQAAIASQRFEGTTSLGEVRTPSQLSDNNCRQ", "length": 336 }, "evidence": [ { "id": "E1BMM4", "url": "https://omabrowser.org/oma/group/E1BMM4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q55CA0-1", "protein_name": "Vacuolar protein sorting-associated protein 26", "gene_name": "vps26", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNFFSNNFGTPCNVEFELDNCQNRKTIEVTQDKGKTEKLFVFIGNEPVSGKVSINIKEKTKKIEHTGIRVEFVGQIELFYDRGNHYEFTSLVRELAPAGELTENKTFSYDFSNVEKQYESYNGTNVRLRYFVRLTIGRSFASNIVKEYDIWVINFVKPPESNSNIKMEVGIEDCLHIEFEYNKSKYHLKDVIIGKIYFLLVRIKIKYMEIALIKRESTGSGPNVFNESETLTKFEIMDGAPVRGESIPVRLFLSVFDLTPTYRSVHNKFSVKYFLNLALVDEDDKKYFKQQEITLWRRGVTKPGLPGSTNNNNNNNTSNTNNTNTPQQKVTESQNEVPEPENNSSDESD", "length": 349 }, "evidence": [ { "id": "E1BMM4", "url": "https://omabrowser.org/oma/group/E1BMM4/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8C0E2-1", "protein_name": "Vacuolar protein sorting-associated protein 26B", "gene_name": "Vps26b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSFFGFGQSVEVEILLNDAESRKRAEHKTEDGKKEKYFLFYDGETVSGKVSLSLKNPNKRLEHQGIKIEFIGQIELYYDRGNHHEFVSLVKDLARPGEITQSQAFDFEFTHVEKPYESYTGQNVKLRYFLRATISRRLNDVVKEMDIVVHTLSTYPELNSSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIKHMEIDIIKRETTGTGPNVYHENDTIAKYEIMDGAPVRGESIPIRLFLAGYELTPTMRDINKKFSVRYYLNLVLIDEEERRYFKQQEVVLWRKGDIVRKSMSHQAAIASQRFEGTTSLGEVRTPGQLSDNNSRQ", "length": 336 }, "evidence": [ { "id": "E1BMM4", "url": "https://omabrowser.org/oma/group/E1BMM4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "retromer, cargo-selective complex", "id": "GO:0030906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030906", "evidence": [ { "database": "UniProtKB", "id": "E1BMM4", "url": "https://www.uniprot.org/uniprotkb/E1BMM4" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "E1BMM4", "url": "https://www.uniprot.org/uniprotkb/E1BMM4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BMM4", "url": "https://www.uniprot.org/uniprotkb/E1BMM4" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "E1BMM4", "url": "https://www.uniprot.org/uniprotkb/E1BMM4" } ], "pmid": "" }, { "name": "postsynaptic recycling endosome", "id": "GO:0098837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098837", "evidence": [ { "database": "UniProtKB", "id": "E1BMM4", "url": "https://www.uniprot.org/uniprotkb/E1BMM4" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "E1BMM4", "url": "https://www.uniprot.org/uniprotkb/E1BMM4" } ], "pmid": "" }, { "name": "phagocytic vesicle", "id": "GO:0045335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045335", "evidence": [ { "database": "UniProtKB", "id": "E1BMM4", "url": "https://www.uniprot.org/uniprotkb/E1BMM4" } ], "pmid": "" }, { "name": "retromer complex", "id": "GO:0030904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030904", "evidence": [ { "database": "UniProtKB", "id": "E1BMM4", "url": "https://www.uniprot.org/uniprotkb/E1BMM4" } ], "pmid": "" }, { "name": "postsynaptic early endosome", "id": "GO:0098842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098842", "evidence": [ { "database": "UniProtKB", "id": "E1BMM4", "url": "https://www.uniprot.org/uniprotkb/E1BMM4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "E1BMM4", "url": "https://www.uniprot.org/uniprotkb/E1BMM4" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "E1BMM4", "url": "https://www.uniprot.org/uniprotkb/E1BMM4" } ], "pmid": "" }, { "name": "regulation of neurotransmitter receptor localization to postsynaptic specialization membrane", "id": "GO:0098696", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098696", "evidence": [ { "database": "UniProtKB", "id": "E1BMM4", "url": "https://www.uniprot.org/uniprotkb/E1BMM4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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"tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BMN7-1", "uniprot_ac": "E1BMN7", "uniprot_id": "E1BMN7_BOVIN", "mass": { "chemical_mass": 131282.0, "monoisotopic_mass": 131282.0 }, "refseq": {}, "gene_names": [ { "name": "ABTB2", "type": "recommended", "evidence": [ { "id": "E1BMN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN7" } ] } ], "protein_names": [ { "name": "Ankyrin repeat and BTB/POZ domain-containing protein 2", "type": "recommended", "evidence": [ { "id": "E1BMN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May be involved in the initiation of hepatocyte growth.", "evidence": [ { "database": "UniProtKB", "id": "E1BMN7", "url": "https://www.uniprot.org/uniprotkb/E1BMN7#function" }, { "database": "UniProtKB", "id": "ARBA00056228", "url": "https://www.uniprot.org/uniprotkb/ARBA00056228#function" }, { "database": "UniProtKB", "id": "A0AAA9TR58", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TR58#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMN7", "url": "https://www.uniprot.org/uniprotkb/E1BMN7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ABTB2", "url": "https://www.uniprot.org/uniprotkb/E1BMN7", "locus": { "chromosome": "15", "start_pos": 64746928, "end_pos": 64932961, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005923", "url": "https://www.ensembl.org/id/ENSBTAG00000005923" } ] } } ], "crossref": [ { "id": "E1BMN7", "url": "https://alphafold.ebi.ac.uk/entry/E1BMN7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005923", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005923", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18350", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18350", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18526", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18526", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22913", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22913", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": 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"PTHR46071", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46071", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46071:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46071:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26281", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26281", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9TR58", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TR58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TR58-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TR58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMN7", "url": "https://www.uniprot.org/uniprotkb/E1BMN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMN7-1", "url": "https://www.uniprot.org/uniprotkb/E1BMN7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIGGPPGLFACRQQPSTQLCRRLAPRRSLQRAFSQVGPGLAQRREPPPSIAAALFSRGPFSAENRRSASGKLRWTRRVAEEEQRRIVPVTARSRDAGSVGLWPPRISPTFLRPPGRRAGDAAAEPRGAERKEGAPESLELVSAHLGKGAWSCERPSLGEAAPGRLPMAGTYSSTLKTLEDLTLDSGYGAGDSCRSLSLSSSKSNSQALNSSAQQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKGAGGRRQPLFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAAVKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVLASQSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYNGGSLGHDERADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQGRHPLCPGSSPARQARQPPQPITWSPDALHTLYYFLRCPQMESMENPNLDPPRMALNNERPFMLLPPLMEWMRVAITYAEHRRSLTVDSGDIRQAARLLLPGLDCEPRQLKPECCFSSFRRLDARAATEKFNQDLGFRMLNCGRTDLISQAIEALGPDGVNTMDDQGMTPLMYACAAGDEAMVQMLIDAGANLDIQVPSNSPRHPSIHPDSRHWTSLTFAVLHGHISVVQLLLDAGAHVEGSAVNGGEDSYAETPLQLASAAGNYELVSLLLSRGADPLLSMLEANGMASSLHEDMNCFSHSAAHGHRNVLRKLLTQPQQAKADVLSLEEILAEGVEDSDASSQGSGSEGPMRLSRTRTKALQEAMYYSAEHGYVDITMELRALGVPWKLHVWIESLRTSFSQSRYSVVQSLLRDFSSIKEEEYNEELVTEGLPLMFDILKTSKNDSVTQQLAAIFMHCYGSSPIPRIPELRKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKSEQDGDGSKTIEIGDMKYHIFQMMMQYLYYGGTESMDIPTSDILELLSAASLFQLDALQRHCEILGSQTLSVDSAVNTYKYAKIHNAPELALFCEGFFLKHMKALLEQDSFRQLIYGRSSKVQGLDPLQDLQSTLAERVHSLYVTSRV", "length": 1191, "header": "tr|E1BMN7-1|E1BMN7_BOVIN Isoform 1 of Ankyrin repeat and BTB/POZ domain-containing protein 2 OS=Bos taurus OX=9913 GN=ABTB2 PE=4 SV=3 CANONICAL=E1BMN7-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TR58-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TR58/entry", "sequence": { "sequence": "MIGGPPGLFACRQQPSTQLCRRLAPRRSLQRAFSQVGPGLAQRREPPPSIAAALFSRGPFSAENRRSASGKLRWTRRVAEEEQRRIVPVTARSRDAGSVGLWPPRISPTFLRPPGRRAGDAAAEPRGAERKEGAPESLELVSAHLGKGAWSCERPSLGEAAPGRLPMAGTYSSTLKTLEDLTLDSGYGAGDSCRSLSLSSSKSNSQALNSSAQQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKGAGGRRQPLFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAAVKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVLASQSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYNGGSLGHDERADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQGRHPLCPGSSPARQARQPPQPITWSPDALHTLYYFLRCPQMESMENPNLDPPRMALNNERPFMLLPPLMEWMRVAITYAEHRRSLTVDSGDIRQAARLLLPGLDCEPRQLKPECCFSSFRRLDARAATEKFNQDLGFRMLNCGRTDLISQAIEALGPDGVNTMDDQGMTPLMYACAAGDEAMVQMLIDAGANLDIQVPSNSPRHPSIHPDSRHWTSLTFAVLHGHISVVQPPPHPHCGETERSAWTLHTWSQLLLDAGAHVEGSAVNGGEDSYAETPLQLASAAGNYELVSLLLSRGADPLLSMLEANGMASSLHEDMNCFSHSAAHGHRNVLRKLLTQPQQAKADVLSLEEILAEGVEDSDASSQGSGSEGPMRLSRTRTKALQEAMYYSAEHGYVDITMELRALGVPWKLHVWIESLRTSFSQSRYSVVQSLLRDFSSIKEEEYNEELVTEGLPLMFDILKTSKNDSVTQQLAAIFMHCYGSSPIPRIPELRKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKSEQDGDGSKTIEIGDMKYHIFQMMMQYLYYGGTESMDIPTSDILELLSAASLFQLDALQRHCEILGSQTLSVDSAVNTYKYAKIHNAPELALFCEGFFLKHMKALLEQDSFRQLIYGRSSKVQGLDPLQDLQSTLAERVHSLYVTSRV", "length": 1213, "header": "tr|A0AAA9TR58-1|A0AAA9TR58_BOVIN Computationally mapped isoform of Ankyrin repeat and BTB/POZ domain-containing protein 2 OS=Bos taurus OX=9913 GN=ABTB2 PE=4 SV=1 CANONICAL=E1BMN7-1" }, "locus": { "chromosome": "15", "start_pos": 64932762, "end_pos": 64747932, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000117718.1", "url": "https://www.ensembl.org/id/ENSBTAT00000117718.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101078.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101078.1" } ] } }, { "isoform_ac": "E1BMN7-1", "url": "https://www.uniprot.org/uniprotkb/E1BMN7/entry", "sequence": { "sequence": "MIGGPPGLFACRQQPSTQLCRRLAPRRSLQRAFSQVGPGLAQRREPPPSIAAALFSRGPFSAENRRSASGKLRWTRRVAEEEQRRIVPVTARSRDAGSVGLWPPRISPTFLRPPGRRAGDAAAEPRGAERKEGAPESLELVSAHLGKGAWSCERPSLGEAAPGRLPMAGTYSSTLKTLEDLTLDSGYGAGDSCRSLSLSSSKSNSQALNSSAQQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKGAGGRRQPLFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAAVKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVLASQSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYNGGSLGHDERADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQGRHPLCPGSSPARQARQPPQPITWSPDALHTLYYFLRCPQMESMENPNLDPPRMALNNERPFMLLPPLMEWMRVAITYAEHRRSLTVDSGDIRQAARLLLPGLDCEPRQLKPECCFSSFRRLDARAATEKFNQDLGFRMLNCGRTDLISQAIEALGPDGVNTMDDQGMTPLMYACAAGDEAMVQMLIDAGANLDIQVPSNSPRHPSIHPDSRHWTSLTFAVLHGHISVVQLLLDAGAHVEGSAVNGGEDSYAETPLQLASAAGNYELVSLLLSRGADPLLSMLEANGMASSLHEDMNCFSHSAAHGHRNVLRKLLTQPQQAKADVLSLEEILAEGVEDSDASSQGSGSEGPMRLSRTRTKALQEAMYYSAEHGYVDITMELRALGVPWKLHVWIESLRTSFSQSRYSVVQSLLRDFSSIKEEEYNEELVTEGLPLMFDILKTSKNDSVTQQLAAIFMHCYGSSPIPRIPELRKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKSEQDGDGSKTIEIGDMKYHIFQMMMQYLYYGGTESMDIPTSDILELLSAASLFQLDALQRHCEILGSQTLSVDSAVNTYKYAKIHNAPELALFCEGFFLKHMKALLEQDSFRQLIYGRSSKVQGLDPLQDLQSTLAERVHSLYVTSRV", "length": 1191, "header": "tr|E1BMN7-1|E1BMN7_BOVIN Isoform 1 of Ankyrin repeat and BTB/POZ domain-containing protein 2 OS=Bos taurus OX=9913 GN=ABTB2 PE=4 SV=3 CANONICAL=E1BMN7-1" }, "locus": { "chromosome": "15", "start_pos": 64932762, "end_pos": 64747932, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000007781.6", "url": "https://www.ensembl.org/id/ENSBTAT00000007781.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000007781.5", "url": "https://www.ensembl.org/id/ENSBTAP00000007781.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1A830-1", "protein_name": "Ankyrin repeat and BTB/POZ domain-containing protein 2", "gene_name": "ABTB2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGIYSSTLKTLEDLTLDSGYGAGDSCRSLSLSSSKSNSQAFTSSQHRGNWWYYSGSMNSRNNSWDTVNTVLPEDPEVADIFSKCPRLPDLEEYPWTDEDVARILRKAKGDGSGRPFSHEAVRRLSQLLRRALIRVSREAQRLSVMHSKCTRFEVQSAVKLIQSWSLAESCVLATVKALSLYSMSAGDGLRKGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIKGRVLASQSPDGGGGEISAEILEVVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYNDGSVCSDGRADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQCLNTIRPGMSPIRQTRQQQPISWSPDALHTLYYFLRCPQMESMENPNLDPPRMTLNNERPFMLLPPLMEWMRVAITYAEHRRSLTVDSDDIRQTARLLLPGLDCEPRQLKPECCFSSFRRLDAKAATEKFQQDLGFRMLNCGRTDLINQAIDALGADGVNTMDDQGMTPLMYACAAGDEAMVQMLIDAGANLDIPVPSTSPRYPSVHPDSRHWTALTFAVLHGHISVVQLLLDAGAHVEGSAVNSGEDNYAETPLQLASAAGNYELVSLLLSRGADPLLSMLEVNGMSSSLHEDMNCFSHSAAHGHRNVLRKLLTQPQQLKGDVLSLEEILAEGVESDTSSQGSSNEGQVKLCKTRMKALQEAMYYSAEHGYVDITMELRGLGVPWKLHVWIESLRTTFYQSRYSVVQTLLREFVTIKEEDYNEELVNEGLQLMFDILKTSKNDSINQQLASIFTHCYGSSPIPSIPEIHKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKTEHDSHGSKTVEISDMKYNIFKMLMQYLYYGGTESMEIPTTDILELLSAASLFQLDGLQRHCEILCAQTISMENSVSIYKYAKIHNAPELAAFCEGFFLKHMSSLLEQDSFRQLIYSRNSKVQGLDPLRDLQTALAGRLHSVYVTSRV", "length": 1017 }, "evidence": [ { "id": "E1BMN7", "url": "https://omabrowser.org/oma/group/E1BMN7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1SGS8-1", "protein_name": "Ankyrin repeat and BTB/POZ domain-containing protein 2", "gene_name": "ABTB2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGTYSSTLKTLEDLTLDSGYGAGDSCRSLSLSSSKSNSQALNSSAQQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKGAGARRLPLFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAAVKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVLASQSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYNGGSLGHDERADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQGRHPLCPGSSPARQARQPPQPITWSPDALHTLYYFLRCPQMESMENPNLDPPRMALNNERPFMLLPPLMEWMRVAITYAEHRRSLTVDSGDIRQAARLLLPGLDCEPRQLKPECCFSSFRRLDARAATEKFNQDLGFRMLNCGRTDLISQAIEALGPDGVNTMDDQGMTPLMYACAAGDEAMVQMLIDAGANLDIQVPSNSPRYPSIHPDSRHWTSLTFAVLHGHISVVQLLLDAGAHVEGSAVNGGEDSFAETPLQLASAAGNYELVSLLLSRGADPLLSMLEANGIASSLHEDMNCFSHSAAHGHRNVLRKLLTQPQQAKADVLSLEEILAEGVEESDASSQGSGSEGPVRLSRTRTKALQEAMYYSAEHGYVDITMELRALGVPWKLHVWIESLRTSFSQSRYSVVQSLLRDFSSIKEEEYNEELVTEGLQLMFDILKTSKNDSVIQQLATIFTHCYGSSPIPSIPELRKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKSEQDGDSSKTIEISDMKYHIFQMMMRYLYYGGTESMDIPTGDILELLSAASLFQLDALQRHCEILCSQTLSVESAVSTYKYAKIHNAPELALFCEGFFLKHMKALLEQDSFRQLIYGRSSKVQGLDPLQDLQSTLAERVHSLYVTSRV", "length": 1025 }, "evidence": [ { "id": "E1BMN7", "url": "https://omabrowser.org/oma/group/E1BMN7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M9PFY3-1", "protein_name": "BTB domain-containing protein", "gene_name": "CG33291", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYCTKDCTCSLCRELRGYKPSDKKSAPSAPTLLSRMLNDNFILRRRGISLKNFQPQSLRNSEMLAQQMPVPRPPQTPSPTPIEELPDWATEDSSRAKKPNHKVVIYFGDSIHRGGQQSPLPSPKELHSQLLQEMSQKLKTSVAEEGLTGVEKVKKVQQMAGQPETSPPANDELPPYIESVQNGVINIRIEGNYRRASALVETVAKPTLAVVAPTKSECDCDAALGDNDDGNADDDSDDPGQDEAETDSCDWSYVQEWRRAAKRPTGNLPPNFVQHQAPSQVTGLPPVPPPQMQSPHQVQSQLPPSQTPLSSQKGLAVAMATPAPRVFKELAQQPNKGMPHKMVASSSSCSGGQANSSCKMPSPGTASKALIPQRAVAGPARLTVQSTPVKSQPPQLSGSLSQSQVSPNRPILGIPTTAANPTPPRIHQHDQFRALQRVQECHSSSDENRSSGHASMSDTGGHSSSPAGGMTLGPLPEDRLAAGVTNRSTRSRRHRGIMPGGKAPWSGTGLEDIKLAMLTLRSQTSSSTYSSLSAGSESSEPARRLGRYSSLETVVTSTSADEFVWVDSHNRLVELQHPPWSQQCILKVLRNGRCQQQAEHLAVEAVSRLGYLLQRALVRIAREIQRFSAGVGLCSKQEVVGALRVVLSSSLADSCTKACLRSAAMFAVPGESALKQSKSARAGLQLSVGRFYRWMTDARLGKFIHEYAAVYLCAGIENLLEEIALQCNGTTAAALDQSIASSGDVWGLLQPFAHLNAGRIASGALALPRWANSLDQVIASSGDFRGHLATCVGSIRELKEKALRTQQEFQLAAALSGSALAALFYFMRCSQLEHTELLAASGCHAGQAQSAAPGGGTSSAGHHVQELCYERAYVVLPPLAEWLRVAAAHAEHRNAMMIDKDDVMQAARLLLPGVDCPIRPVAHDEELPTKKTHFNTAPTVSSTGTGTGSSSCSSPVVSGIGIGIGEDTSELGRRATIGVAFKLLLTGRAELLAQAAQLLPPTTRYDTQNSAGLTALMIASIRNDEVALHALLDAGCDPNVEVPPAGSAGYPAIQPDTQHWTALSFAASRANYVALRILLERGGKVEGGARSSEEKCTLTPLQLAAGTGNLEIVALLLAHGANAFLSTQQKDSLCFAGSAQKGCFCAISVAAAHGHRSCLRKLLTHPVSPGTRDVLSLEEMLAEGDVGGVRGSGGPTGAGGPNSASASGNNEDILPLLNKTQIKRLQEAMYHSAENNHLDITIELRKLGVPWTLHCWMHALSAAHDLRLDAVIDQLLQDFLQVCPDDYSAQFVSECLPLLFNIFRNKNEGTTLLLADIFATCFGWETLPPVKEQPPMQPVQGSRIDPKFVNNPELSDVTFRVEGKIFYGHKIVLVTASPRFQSMLSSKLSEGSSTPTVQINDIRYHIFQLVMQFLYCGGCSSLDVAHGDVLELMAAASFFQLEGLLRYTEARCSEMVDVDNVVAMYIHAKVYNANRLLEFCQCFLLQNMVALLTYDDSVKRLLFAKKIPNHDVLAGLLQTLQNRLKARKPNSGGGLVNSYRSPPVTPVKK", "length": 1549 }, "evidence": [ { "id": "E1BMN7", "url": "https://omabrowser.org/oma/group/E1BMN7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O08764-1", "protein_name": "Ankyrin repeat and BTB/POZ domain-containing protein 2", "gene_name": "Abtb2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGTYSSTLKTLEDLTLDSGYGAGDSCRSLSLSSSKSNSQALNSSAPQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKSVGGRRLPSFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAAVKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVLASQSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYNGGSLGHDERADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQGRHPLCPGTSPARQARQPPQPITWSPDALHTLYYFLRCPQMESMENPNLDPPRMTLNNERPFMLLPPLMEWMRVAITYAEHRRSLTVDSGDIRQAARLLLPGLDCEPRQLKPECCFSSFRRLDARAATERFNQDLGFRMLNCGRTDLISQPSSPGPDGVNTMDDQGLTPLMYACATGDEAMVQMLIDAGANLDIQVPSNSPRHPSVHPDSRHWTSLTFAVLHGHISVVQLLLDAGAHVEGSAVNSGEDSYAETPLQLASAAGNYELVSLLLSRGADPLLSMLEANGMASSLHEDMNCFSHSAAHGHRNVLRKLLTQPQQAKADVLSLEEILAEGVEESDTSSQGSSEGPVRLSRTRTKALQEAMYYSAEHGYVDITMELRALGVPWKLHIWIESLRTSFSQSRYSVVQGLLRDFSSIKEEEYNEELVTEGLQLMFDILKTSKNDSVLQQLATIFTHCYGTSPIPSIPEIRKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKSEQDGDNSKTIEISDIKYHIFQMLMQYLYYGGTESMEIPTADILQLLSAANLFQLDALQRHCEILCSQTLSVESAVNTYKYAKIHNAPELALFCEGFFLKHMKALLEQMPSGSSSMAEAAKSRAWTHCRICRAP", "length": 1009 }, "evidence": [ { "id": "E1BMN7", "url": "https://omabrowser.org/oma/group/E1BMN7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TQI7-1", "protein_name": "Ankyrin repeat and BTB/POZ domain-containing protein 2", "gene_name": "Abtb2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGTYSSTLKTLEDLTLDSGYGAGDSCRSLSLSSSKSNSQALNSSAQQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKSVGGRRLPSFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAAVKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVLASQSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYNGGSLGHDERADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQGRHPLCPGTSPARQARQPPQPITWSPDALHTLYYFLRCPQMESMENPNLDPPRMTLNNERPFMLLPPLMEWMRVAITYAEHRRSPTVDSGDIRQAARLLLPGLDCEPRQLKPECCFSSFRRLDARAATERFNQDLGFRMLNCGRTDLISQAIEALGPDGVNTMDDQGMTPLMYACAAGDEAMVQMLIDAGANLDIQVPSHSPRHPSVHPDSRHWTSLTFAVLHGHISVVQLLLDAGAHVEGSAVNSGEDSYAETPLQLASAAGNYELVSLLLSRGADPLLSMLEANGMASSLHEEMNCFSHSAAHGHRNVLRKLLTQPQQAKADVLSLEEILAEGVEESDTSSQGSSEGPVRLSRTRTKALQEAMYYSAEHGYLDITMELRALGVPWKLHIWIESLRTSFSQSRYSVVQSLLKDFSSIKEEEYNEELVTEGLQLMFDILKTSKNDSVLQQLATIFTHCYGTSPIPSIPEIRKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKSEQDGDSSKTIEISDIKYHIFQMLMQYLYYGGTESMEIPTADILQLLSAANLFQLDALQRHCEILCSQTLSVESAVNTYKYAKIHNAPELALFCEGFFLKHMKALLEQDAFRQLIYGRSSKVQGLDPLQDLQSTLAERVHSVYVTSRV", "length": 1024 }, "evidence": [ { "id": "E1BMN7", "url": "https://omabrowser.org/oma/group/E1BMN7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N961-1", "protein_name": "Ankyrin repeat and BTB/POZ domain-containing protein 2", "gene_name": "ABTB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGTYSSTLKTLEDLTLDSGYGAGDSCRSLSLSSSKSNSQALNSSAQQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKGAGGRRLPQFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAAVKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVMASHSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYNGGSLGHDERADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQGRHPLCPGASPARQARQPPQPITWSPDALHTLYYFLRCPQMESMENPNLDPPRMTLNNERPFMLLPPLMEWMRVAITYAEHRRSLTVDSGDIRQAARLLLPGLDCEPRQLKPEHCFSSFRRLDARAATEKFNQDLGFRMLNCGRTDLINQAIEALGPDGVNTMDDQGMTPLMYACAAGDEAMVQMLIDAGANLDIQVPSNSPRHPSIHPDSRHWTSLTFAVLHGHISVVQLLLDAGAHVEGSAVNGGEDSYAETPLQLASAAGNYELVSLLLSRGADPLLSMLEAHGMGSSLHEDMNCFSHSAAHGHRNVLRKLLTQPQQAKADVLSLEEILAEGVEESDASSQGSGSEGPVRLSRTRTKALQEAMYYSAEHGYVDITMELRALGVPWKLHIWIESLRTSFSQSRYSVVQSLLRDFSSIREEEYNEELVTEGLQLMFDILKTSKNDSVIQQLATIFTHCYGSSPIPSIPEIRKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKSEQDGDSSKTIEISDMKYHIFQMMMQYLYYGGTESMEIPTTDILELLSAASLFQLDALQRHCEILCSQTLSMESAVNTYKYAKIHNAPELALFCEGFFLKHMKALLEQDAFRQLIYGRSSKVQGLDPLQDLQNTLAERVHSVYITSRV", "length": 1025 }, "evidence": [ { "id": "E1BMN7", "url": "https://omabrowser.org/oma/group/E1BMN7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "E1BMN7", "url": "https://www.uniprot.org/uniprotkb/E1BMN7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BMN7", "url": "https://www.uniprot.org/uniprotkb/E1BMN7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1042, "end_pos": 1044, "annotation": "n_glycosylation_sequon" }, { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 966, "end_pos": 968, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMN7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1191, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMN7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMN7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BMN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN7" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 1011, "end_pos": 1080, "start_aa": "Ser", "end_aa": "Asp", "glycosite_overlap": [] } ], 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BMP0-1", "uniprot_ac": "E1BMP0", "uniprot_id": "E1BMP0_BOVIN", "mass": { "chemical_mass": 66538.0, "monoisotopic_mass": 66538.0 }, "refseq": {}, "gene_names": [ { "name": "EFCC1", "type": "recommended", "evidence": [ { "id": "E1BMP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP0" } ] } ], "protein_names": [ { "name": "EF-hand and coiled-coil domain containing 1", "type": "synonym", "evidence": [ { "id": "E1BMP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMP0", "url": "https://www.uniprot.org/uniprotkb/E1BMP0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "EFCC1", "url": "https://www.uniprot.org/uniprotkb/E1BMP0", "locus": { "chromosome": "22", "start_pos": 59009178, "end_pos": 58979773, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005922", "url": "https://www.ensembl.org/id/ENSBTAG00000005922" } ] } } ], "crossref": [ { "id": "E1BMP0", "url": "https://alphafold.ebi.ac.uk/entry/E1BMP0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005922", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005922", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031601", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031601", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BMP0", "url": "https://www.orthodb.org/?gene=E1BMP0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF15799", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15799", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BMP0", "url": "https://www.uniprot.org/uniprotkb/E1BMP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMP0-1", "url": "https://www.uniprot.org/uniprotkb/E1BMP0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGAASDPYRRPARRTQWLLSALAHHYGLDRGVENEIVVLATGLDQYLQEVFHHLDSRGAGRLPRADFRALCAVLGLRFEGAAAPGEASGDTAAGDTNSGDVISGDAAAGEAAEWDEDAEEEARLALRAEPPELTFRQFHARLCGYFGTRAGPRLPRGALSEHIETQIRLRRPRRRRRRAARPPGPDGGPDGERLARLEEENSSLRELVEDLRAALQSSDARCLALQVGLWKSQAGAQEAARGEPEAAARELRQARGALAAAEAQAGRLRRGQAEVRRRAEEARAAVLRSLGRVRELEALARQMPGLQRGLRLLEGELRRYRSEGTQLPGPSRASPEPDTKSSEPEDGEARGPEPPPEGAWGSGNSPASRPPGPARASPGLDEQLFRSVEGQAASDEEDDREKWQEAQRLPAEVTALLAGLSGCGSGLEQTLESSPPCASTLLHCRCDDQTAKKLMTYCSHLGGANHAHALGELETCVAMLVEQLGSRGCGAKTLRTPEEEAELQRKVGENESLRQELQMVEAERVRLSLLEEKLEDVLGLLQRLRDLNISKKALGKILLSTLDACRDPAHDGLSGPLAVLEALHRALAGCELLRREPSAPASTAPALTHSFPISG", "length": 616, "header": "tr|E1BMP0-1|E1BMP0_BOVIN Isoform 1 of EF-hand and coiled-coil domain containing 1 OS=Bos taurus OX=9913 GN=EFCC1 PE=4 SV=4 CANONICAL=E1BMP0-1" }, "isoforms": [ { "isoform_ac": "E1BMP0-1", "url": "https://www.uniprot.org/uniprotkb/E1BMP0/entry", "sequence": { "sequence": "MEGAASDPYRRPARRTQWLLSALAHHYGLDRGVENEIVVLATGLDQYLQEVFHHLDSRGAGRLPRADFRALCAVLGLRFEGAAAPGEASGDTAAGDTNSGDVISGDAAAGEAAEWDEDAEEEARLALRAEPPELTFRQFHARLCGYFGTRAGPRLPRGALSEHIETQIRLRRPRRRRRRAARPPGPDGGPDGERLARLEEENSSLRELVEDLRAALQSSDARCLALQVGLWKSQAGAQEAARGEPEAAARELRQARGALAAAEAQAGRLRRGQAEVRRRAEEARAAVLRSLGRVRELEALARQMPGLQRGLRLLEGELRRYRSEGTQLPGPSRASPEPDTKSSEPEDGEARGPEPPPEGAWGSGNSPASRPPGPARASPGLDEQLFRSVEGQAASDEEDDREKWQEAQRLPAEVTALLAGLSGCGSGLEQTLESSPPCASTLLHCRCDDQTAKKLMTYCSHLGGANHAHALGELETCVAMLVEQLGSRGCGAKTLRTPEEEAELQRKVGENESLRQELQMVEAERVRLSLLEEKLEDVLGLLQRLRDLNISKKALGKILLSTLDACRDPAHDGLSGPLAVLEALHRALAGCELLRREPSAPASTAPALTHSFPISG", "length": 616, "header": "tr|E1BMP0-1|E1BMP0_BOVIN Isoform 1 of EF-hand and coiled-coil domain containing 1 OS=Bos taurus OX=9913 GN=EFCC1 PE=4 SV=4 CANONICAL=E1BMP0-1" }, "locus": { "chromosome": "22", "start_pos": 59007988, "end_pos": 58979972, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000007776.7", "url": "https://www.ensembl.org/id/ENSBTAT00000007776.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000007776.7", "url": "https://www.ensembl.org/id/ENSBTAP00000007776.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "E1BMP0", "url": "https://www.uniprot.org/uniprotkb/E1BMP0" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "E1BMP0", "url": "https://www.uniprot.org/uniprotkb/E1BMP0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "E1BMP0", "url": "https://www.uniprot.org/uniprotkb/E1BMP0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 511, "end_pos": 513, "annotation": "n_glycosylation_sequon" }, { "start_pos": 549, "end_pos": 551, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMP0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 616, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMP0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMP0" } ], "lectin_list": [], "domain_list": [ { 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BMP5-1", "uniprot_ac": "E1BMP5", "uniprot_id": "E1BMP5_BOVIN", "mass": { "chemical_mass": 30434.0, "monoisotopic_mass": 30434.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "E1BMP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMP5", "url": "https://www.uniprot.org/uniprotkb/E1BMP5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/E1BMP5", "locus": {} } ], "crossref": [ { "id": "E1BMP5", "url": "https://alphafold.ebi.ac.uk/entry/E1BMP5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020516", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020516", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR040022", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040022", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BMP5", "url": "https://www.orthodb.org/?gene=E1BMP5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR37353", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37353", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37353:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37353:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17673", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17673", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BMP5", "url": "https://www.uniprot.org/uniprotkb/E1BMP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMP5-1", "url": "https://www.uniprot.org/uniprotkb/E1BMP5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFNRDMDPSKEGEEDESLTCSLPELYAFAENFNKENKKLNLLKMHCISPGEAQRMLSQKHFLNGTGGTDGRADDSLPVFTCKVVRREERPESMTELLHRSLLTRSLSPVERLSKSQQRISEYGIPPPVHTFPYEILIDHSKFVSMVTIRKKIQSTKILCRLGIPCVSPEKFIFEDKAPKYFLIDPAKQFMDLRDLEWKFYKGLVKWKRCISDEFSDIKNDSEKRFVGSQQLPHPLSPPLVHKSLVIYPKVDYPRYHLLKNI", "length": 262, "header": "tr|E1BMP5-1|E1BMP5_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=4 SV=4 CANONICAL=E1BMP5-1" }, "isoforms": [ { "isoform_ac": "E1BMP5-1", "url": "https://www.uniprot.org/uniprotkb/E1BMP5/entry", "sequence": { "sequence": "MSFNRDMDPSKEGEEDESLTCSLPELYAFAENFNKENKKLNLLKMHCISPGEAQRMLSQKHFLNGTGGTDGRADDSLPVFTCKVVRREERPESMTELLHRSLLTRSLSPVERLSKSQQRISEYGIPPPVHTFPYEILIDHSKFVSMVTIRKKIQSTKILCRLGIPCVSPEKFIFEDKAPKYFLIDPAKQFMDLRDLEWKFYKGLVKWKRCISDEFSDIKNDSEKRFVGSQQLPHPLSPPLVHKSLVIYPKVDYPRYHLLKNI", "length": 262, "header": "tr|E1BMP5-1|E1BMP5_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=4 SV=4 CANONICAL=E1BMP5-1" }, "locus": { "chromosome": "8", "start_pos": 79408913, "end_pos": 79402783, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027335.6", "url": "https://www.ensembl.org/id/ENSBTAT00000027335.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027335.6", "url": "https://www.ensembl.org/id/ENSBTAP00000027335.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMP5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 262, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMP5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMP5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 220, "end_pos": 222 }, { "start_pos": 64, "end_pos": 66 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BMQ8-1", "uniprot_ac": "E1BMQ8", "uniprot_id": "E1BMQ8_BOVIN", "mass": { "chemical_mass": 46418.0, "monoisotopic_mass": 46418.0 }, "refseq": {}, "gene_names": [ { "name": "WDR31", "type": "recommended", "evidence": [ { "id": "E1BMQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMQ8" } ] } ], "protein_names": [ { "name": "WD repeat domain 31", "type": "synonym", "evidence": [ { "id": "E1BMQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMQ8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMQ8", "url": "https://www.uniprot.org/uniprotkb/E1BMQ8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "WDR31", "url": "https://www.uniprot.org/uniprotkb/E1BMQ8", "locus": { "chromosome": "8", "start_pos": 102554947, "end_pos": 102595085, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005884", "url": "https://www.ensembl.org/id/ENSBTAG00000005884" } ] } } ], "crossref": [ { "id": "E1BMQ8", "url": "https://alphafold.ebi.ac.uk/entry/E1BMQ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005884", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005884", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "528277", "url": "https://www.ncbi.nlm.nih.gov/gene/528277", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BMQ8", "url": "https://www.orthodb.org/?gene=E1BMQ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19869", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19869", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19869:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19869:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9S4G6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4G6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S4G6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4G6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SEC8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SEC8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SUR5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SUR5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TB98", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TB98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TB98-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TB98-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4G1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4G1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4G1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4G1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMQ8", "url": "https://www.uniprot.org/uniprotkb/E1BMQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMQ8-1", "url": "https://www.uniprot.org/uniprotkb/E1BMQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLLRCHLKRALPQKVSCRFCAVMGKLQSKFKHSTYKYSRPDGFIEEKIQTKAFQEYSPAHVDTVSVVAALNSDLCVSGGKDKTAVAYNWRTGNVVKRFKGHEREITKIACIYKSSQFFSASRDKMVMMWDLQSSSQPRQQFSGHTMVVTGLTVSPDSSQLCTGSRDNTLLLWDVGTGQCAERASVSRNLVTHLCWVPREHYILQTSEDKTIRLWDSRGLQVAHTFPTQQHIQTYCEVSEDGHKCVSCSSGFEGEGCEATLWDLRQTRSRICEYRGHFQTVASCIFLPRALASMPAIATSSHDCKVKIWNQDTGACLFTLSLDGSGPLTSLAVADSVSLLCTSYQLFGSKEILLTRGLGVVDRCLRESPAAAAAAKSLQPCPTLCDPIDGSPPGSPVPGILQARVLEWVPLPSPGKVLASLN", "length": 422, "header": "tr|E1BMQ8-1|E1BMQ8_BOVIN Isoform 1 of WD repeat domain 31 OS=Bos taurus OX=9913 GN=WDR31 PE=4 SV=2 CANONICAL=E1BMQ8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S4G6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4G6/entry", "sequence": { "sequence": "MLLLRCHLKRALPQKVSCRFCAVMGKLQSKFKHSTYKYSRPDGFIEEKIQTKAFQEYSPAHVDTVSVVAALNSDLCVSGGKDKTAVAYNWRTGNVVKRFKGHEREITKIACIYKSSQFFSASRDKMVMMWDLQSSSQPRQQFSGHTMVVTGLTVSPDSSQLCTGSRDNTLLLWDVGTGQCAERASVSRNLVTHLCWVPREHYILQTSEDKTIRLWDSRGLQVAHTFPTQQHIQTYCEVSEDGHKCVSCSSGFEGEGCEATLWDLRQTRSRICEYRGHFQTVASCIFLPRALASMPAIATSSHDCKVKIWNQDTGGLHTGEVTEALWKRSQNHYTDEQGLLGPSSPARPTAECSH", "length": 354, "header": "tr|A0AAA9S4G6-1|A0AAA9S4G6_BOVIN Computationally mapped isoform of WD repeat domain 31 OS=Bos taurus OX=9913 GN=WDR31 PE=4 SV=1 CANONICAL=E1BMQ8-1" }, "locus": { "chromosome": "8", "start_pos": 102585633, "end_pos": 102566041, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089388.1", "url": "https://www.ensembl.org/id/ENSBTAT00000089388.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080049.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080049.1" } ] } }, { "isoform_ac": "A0AAA9SEC8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEC8/entry", "sequence": { "sequence": "MLLLRCHLKRALPQKVSCRFCAVMGKLQSKFKHSTYKYSRPDGFIEEKIQTKAFQEYSPAHVDTVSVVAALNSDLCVSGGKDKIACIYKSSQFFSASRDKMVMMWDLQSSSQPRQQFSGHTMVVTGLTVSPDSSQLCTGSRDNTLLLWDVGTGQCAERASVSRNLVTHLCWVPREHYILQTSEDKTIRLWDSRGLQVAHTFPTQQHIQTYCEVSEDGHKCVSCSSGFEGEGCEATLWDLRQTRSRICEYRGHFQTVASCIFLPRALASMPAIATSSHDCKVKIWNQDTGACLFTLSLDGSGPLTSLAVADSVSLLCVSFSRGIHLLRVDRSQGLELREVAAF", "length": 342, "header": "tr|A0AAA9SEC8-1|A0AAA9SEC8_BOVIN Computationally mapped isoform of WD repeat domain 31 OS=Bos taurus OX=9913 GN=WDR31 PE=4 SV=1 CANONICAL=E1BMQ8-1" }, "locus": { "chromosome": "8", "start_pos": 102585633, "end_pos": 102571584, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119365.1", "url": "https://www.ensembl.org/id/ENSBTAT00000119365.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083753.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083753.1" } ] } }, { "isoform_ac": "A0AAA9SUR5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUR5/entry", "sequence": { "sequence": "MLLLRCHLKRALPQKVSCRFCAVMGKLQSKFKHSTYKYSRPDGFIEEKIQTKAFQEYSPAHVDTVSVVAALNSDLCVSGGKDKTAVAYNWRTGNVVKRFKGHEREITKIACIYKSSQFFSASRDKMVMMWDLQSSSQPRQQFSGHTMVVTGLTVSPDSSQLCTGSRDNTLLLWDVGTGQCAERASVSRNLVTHLCWVPREHYILQTSEDKTIRLWDSRGLQVAHTFPTQQHIQTYCEVSEDGHKCVSCSSGFEGEGCEATLWDLRQTRSRICEYRGHFQTVASCIFLPRALASMPAIATSSHDCKVKIWNQDTGACLFTLSLDGSGPLTSLAVADSVSLLCRNKCYASLRFSLRACSFTFTLLEPSCCSEASTLER", "length": 376, "header": "tr|A0AAA9SUR5-1|A0AAA9SUR5_BOVIN Computationally mapped isoform of WD repeat domain 31 OS=Bos taurus OX=9913 GN=WDR31 PE=4 SV=1 CANONICAL=E1BMQ8-1" }, "locus": { "chromosome": "8", "start_pos": 102585633, "end_pos": 102566142, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102840.1", "url": "https://www.ensembl.org/id/ENSBTAT00000102840.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090204.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090204.1" } ] } }, { "isoform_ac": "A0AAA9TB98-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TB98/entry", "sequence": { "sequence": "MLLLRCHLKRALPQKVSCRFCAVMGKLQSKFKHSTYKYSRPDGFIEEKIQTKAFQEYSPAHVDTVSVVAALNSDLCVSGGKDKTAVAYNWRTGNVVKRFKGHEREITKIACIYKSSQFFSASRDKMVMMWDLQSSSQPRQQFSGHTMVVTGLTVSPDSSQLCTGSRDNTLLLWDVGTGQCAERASVSRNLVTHLCWVPREHYILQTSEDKTIRLWDSRGLQVAHTFPTQQHIQTYCEVSEDGHKCVSCSSGFEGEGCEATLWDLRQTRSRICEYRGHFQTVASCIFLPRALASMPAIATSSHDCKVKIWNQDTGACLFTLSLDGSGPLTSLAVADSVSLLCARILEWVATSPGDLPDPGIKPGSSALQAGSFPTELQDRSSISKIQIPIHSET", "length": 393, "header": "tr|A0AAA9TB98-1|A0AAA9TB98_BOVIN Computationally mapped isoform of WD repeat domain 31 OS=Bos taurus OX=9913 GN=WDR31 PE=4 SV=1 CANONICAL=E1BMQ8-1" }, "locus": { "chromosome": "8", "start_pos": 102585633, "end_pos": 102554957, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116851.1", "url": "https://www.ensembl.org/id/ENSBTAT00000116851.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094121.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094121.1" } ] } }, { "isoform_ac": "A0ABI0P4G1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4G1/entry", "sequence": { "sequence": "MLLLRCHLKRALPQKVSCRFCAVMGKLQSKFKHSTYKYSRPDGFIEEKIQTKAFQEYSPAHVDTVSVVAALNSDLCVSGGKDKTAVAYNWRTGNVVKRFKGHEREITKIACIYKSSQFFSASRDKMVMMWDLQSSSQPRQQFSGHTMVVTGLTVSPDSSQLCTGSRDNTLLLWDVGTGQCAERASVSRNLVTHLCWVPREHYILQTSEDKTIRLWDSRGLQVAHTFPTQQHIQTYCEVSEDGHKCVSCSSGFEGEGCEATLWDLRQTRSRICEYRGHFQTVASCIFLPRALASMPAIATSSHDCKVKIWNQDTGACLFTLSLDGSGPLTSLAVADSVSLL", "length": 340, "header": "tr|A0ABI0P4G1-1|A0ABI0P4G1_BOVIN Computationally mapped isoform of WD repeat domain 31 OS=Bos taurus OX=9913 GN=WDR31 PE=4 SV=1 CANONICAL=E1BMQ8-1" }, "locus": { "chromosome": "8", "start_pos": 102585633, "end_pos": 102571664, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139738.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139738.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106452.1", "url": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377380" }, "gene_names": [ { "name": "OR5F2B", "type": "recommended", "evidence": [ { "id": "E1BMR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMR5" } ] }, { "name": "OR5F1", "type": "synonym", "evidence": [ { "id": "NP_001377380", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377380" } ] }, { "name": "OR5F2B", "type": "synonym", "evidence": [ { "id": "NP_001377380", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377380" } ] } ], "protein_names": [ { "name": "Olfactory receptor family 5 subfamily F member 2B", "type": "synonym", "evidence": [ { "id": "E1BMR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMR5/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 5 subfamily F member 2B", "type": "synonym", "evidence": [ { "id": "NP_001377380", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377380" } ] }, { "name": "olfactory receptor, family 5, subfamily F, member 1", "type": "synonym", "evidence": [ { "id": "NP_001377380", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377380" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377380", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377380" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "E1BMR5", "url": "https://www.uniprot.org/uniprotkb/E1BMR5#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMR5", "url": "https://www.uniprot.org/uniprotkb/E1BMR5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR5F2B", "url": "https://www.uniprot.org/uniprotkb/E1BMR5", "locus": { "chromosome": "15", "start_pos": 78730146, "end_pos": 78731102, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000063165", "url": "https://www.ensembl.org/id/ENSBTAG00000063165" } ] } } ], "crossref": [ { "id": "E1BMR5", "url": "https://alphafold.ebi.ac.uk/entry/E1BMR5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000052333", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000052333", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15411", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15411", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "785930", "url": "https://www.ncbi.nlm.nih.gov/gene/785930", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:785930", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:785930", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HMSHAQC", "url": "https://omabrowser.org/oma/group/HMSHAQC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BMR5", "url": "https://www.orthodb.org/?gene=E1BMR5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377380", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377380", "database": "RefSeq", 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"name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BMR5", "url": "https://www.uniprot.org/uniprotkb/E1BMR5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMR5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 318, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMR5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMR5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BMR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMR5" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22538", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BMR6", "url": "https://www.orthodb.org/?gene=E1BMR6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", 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"database": "Ensembl Peptide", "id": "ENSBTAP00000003368.7", "url": "https://www.ensembl.org/id/ENSBTAP00000003368.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BMR6", "url": "https://www.uniprot.org/uniprotkb/E1BMR6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BMR6", "url": "https://www.uniprot.org/uniprotkb/E1BMR6" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BMR6", "url": "https://www.uniprot.org/uniprotkb/E1BMR6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BMR6", "url": "https://www.uniprot.org/uniprotkb/E1BMR6" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BMR6", "url": "https://www.uniprot.org/uniprotkb/E1BMR6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BMR6", "url": "https://www.uniprot.org/uniprotkb/E1BMR6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BMR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMR6" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 354, "end_pos": 383, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": 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"sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BMR9-1", "uniprot_ac": "E1BMR9", "uniprot_id": "E1BMR9_BOVIN", "mass": { "chemical_mass": 133839.0, "monoisotopic_mass": 133839.0 }, "refseq": {}, "gene_names": [ { "name": "VWA3A", "type": "recommended", "evidence": [ { "id": "E1BMR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMR9" } ] } ], "protein_names": [ { "name": "von Willebrand factor A domain containing 3A", "type": "synonym", "evidence": [ { "id": "E1BMR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMR9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMR9", "url": "https://www.uniprot.org/uniprotkb/E1BMR9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": 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Gene", "id": "ENSBTAG00000069939", "url": "https://www.ensembl.org/id/ENSBTAG00000069939" } ] } } ], "crossref": [ { "id": "E1BMX9", "url": "https://alphafold.ebi.ac.uk/entry/E1BMX9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005240", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005240", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "782885", "url": "https://www.ncbi.nlm.nih.gov/gene/782885", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BMX9", "url": "https://www.orthodb.org/?gene=E1BMX9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381:SF390", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381:SF390", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381:SF455", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381:SF455", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015330923", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015330923", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9U0Z9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0Z9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U0Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0Z9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMX9", "url": "https://www.uniprot.org/uniprotkb/E1BMX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMX9-1", "url": "https://www.uniprot.org/uniprotkb/E1BMX9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNDIISNKIPIATLGHGSQDQDLCEIRKKRPQDLGCIPIFDQMFRVSGQREVTERADFPELGKMMKSQISFEDVAVNFTLEEWQLLNPTQKTLYRDVMLENYSNLVLLGYQVIKPEMIFKLEQENPWLLDEEILSQNFSEKVWLDNNLKMWHQDNQDKLKSLERGHEYDIFERMFHLGINFDHLGMRSHKCGTGEKSLKDPFDFLIPKSNCERKKLDELNRKLLFCIKPARTYGGIKYSDGNTCRKVSSKEPGLIMSHIPHTGVCLCMECGKVFNKKSQLIIHQRTHTGEKPYGCRDCGKAFSQKSLLTIHQRTHSGEKPYGCGECQKAFSRKSLLILHQRTHTGEKPYGCSDCGKAFSRKSQLKRHQITHTIEKPYGCSDCGKVFSQKLKLITHQRTHTGEKPYRCSDCGKAFFWKSQLITHQRVHTGKKPYACSECKKAFSRNSLLIRHQRIHTGEKPYECSECGEAFIRKPQLVKHQMTHTGEKNYQCSNCEEAFFKKSELIKHQKVHLGERPYGCVECGKTFFGKSQLLTHQRTHTGEKPYECSACGKAFTQKSSLVSHQRTHTGEKPYECSECGKTFSEKSSLIHHQRTHTGEKPFECGECRKAFAWKPQLLRHQRIHTGEKPYGCSECGKAFVQKVQLIKHQRNHTGEKTYGCNDCAKAFFEKAQLIIHQRIHTGERPYKCEECGKSFTRKSHLMRHQRIHTGDKYYGCSECGTVFHRKAQLLIHQRSHML", "length": 737, "header": "tr|E1BMX9-1|E1BMX9_BOVIN Isoform 1 of Zinc finger protein 605 OS=Bos taurus OX=9913 GN=ZNF605 PE=3 SV=4 CANONICAL=E1BMX9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9U0Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0Z9/entry", "sequence": { "sequence": "MDWAHAPFPKICSISLMIREIYTVWFIFSFLEKVWLDNNLKMWHQDNQDKLKSLERGHEYDIFERMFHLGINFDHLGMRSHKCGTGEKSLKDPFDFLIPKSNCERKKLDELNRKLLFCIKPARTYGGIKYSDGNTCRKVSSKEPGLIMSHIPHTGVCLCMECGKVFNKKSQLIIHQRTHTGEKPYGCRDCGKAFSQKSLLTIHQRTHSGEKPYGCGECQKAFSRKSLLILHQRTHTGEKPYGCSDCGKAFSRKSQLKRHQITHTIEKPYGCSDCGKVFSQKLKLITHQRTHTGEKPYRCSDCGKAFFWKSQLITHQRVHTGKKPYACSECKKAFSRNSLLIRHQRIHTGEKPYECSECGEAFIRKPQLVKHQMTHTGEKNYQCSNCEEAFFKKSELIKHQKVHLGERPYGCVECGKTFFGKSQLLTHQRTHTGEKPYECSACGKAFTQKSSLVSHQRTHTGEKPYECSECGKTFSEKSSLIHHQRTHTGEKPFECGECRKAFAWKPQLLRHQRIHTGEKPYGCSECGKAFVQKVQLIKHQRNHTGEKTYGCNDCAKAFFEKAQLIIHQRIHTGERPYKCEECGKSFTRKSHLMRHQRIHTGDKYYGCSECGTVFHRKAQLLIHQRSHML", "length": 629, "header": "tr|A0AAA9U0Z9-1|A0AAA9U0Z9_BOVIN Computationally mapped isoform of Zinc finger protein 605 OS=Bos taurus OX=9913 GN=ZNF605 PE=3 SV=1 CANONICAL=E1BMX9-1" }, "locus": { "chromosome": "17", "start_pos": 43939226, "end_pos": 43936237, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120881.1", "url": "https://www.ensembl.org/id/ENSBTAT00000120881.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088157.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088157.1" } ] } }, { "isoform_ac": "E1BMX9-1", "url": "https://www.uniprot.org/uniprotkb/E1BMX9/entry", "sequence": { "sequence": "MNDIISNKIPIATLGHGSQDQDLCEIRKKRPQDLGCIPIFDQMFRVSGQREVTERADFPELGKMMKSQISFEDVAVNFTLEEWQLLNPTQKTLYRDVMLENYSNLVLLGYQVIKPEMIFKLEQENPWLLDEEILSQNFSEKVWLDNNLKMWHQDNQDKLKSLERGHEYDIFERMFHLGINFDHLGMRSHKCGTGEKSLKDPFDFLIPKSNCERKKLDELNRKLLFCIKPARTYGGIKYSDGNTCRKVSSKEPGLIMSHIPHTGVCLCMECGKVFNKKSQLIIHQRTHTGEKPYGCRDCGKAFSQKSLLTIHQRTHSGEKPYGCGECQKAFSRKSLLILHQRTHTGEKPYGCSDCGKAFSRKSQLKRHQITHTIEKPYGCSDCGKVFSQKLKLITHQRTHTGEKPYRCSDCGKAFFWKSQLITHQRVHTGKKPYACSECKKAFSRNSLLIRHQRIHTGEKPYECSECGEAFIRKPQLVKHQMTHTGEKNYQCSNCEEAFFKKSELIKHQKVHLGERPYGCVECGKTFFGKSQLLTHQRTHTGEKPYECSACGKAFTQKSSLVSHQRTHTGEKPYECSECGKTFSEKSSLIHHQRTHTGEKPFECGECRKAFAWKPQLLRHQRIHTGEKPYGCSECGKAFVQKVQLIKHQRNHTGEKTYGCNDCAKAFFEKAQLIIHQRIHTGERPYKCEECGKSFTRKSHLMRHQRIHTGDKYYGCSECGTVFHRKAQLLIHQRSHML", "length": 737, "header": "tr|E1BMX9-1|E1BMX9_BOVIN Isoform 1 of Zinc finger protein 605 OS=Bos taurus OX=9913 GN=ZNF605 PE=3 SV=4 CANONICAL=E1BMX9-1" }, "locus": { "chromosome": "17", "start_pos": 43994432, "end_pos": 43972113, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006896.7", "url": "https://www.ensembl.org/id/ENSBTAT00000006896.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006896.7", "url": "https://www.ensembl.org/id/ENSBTAP00000006896.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BMX9", "url": "https://www.uniprot.org/uniprotkb/E1BMX9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BMX9", "url": "https://www.uniprot.org/uniprotkb/E1BMX9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BMX9", "url": "https://www.uniprot.org/uniprotkb/E1BMX9" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "E1BMX9", "url": "https://www.uniprot.org/uniprotkb/E1BMX9" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "E1BMX9", "url": "https://www.uniprot.org/uniprotkb/E1BMX9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 650, "end_pos": 652, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMX9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 737, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMX9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMX9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BMX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMX9" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 265, "end_pos": 292, "start_aa": "Cys", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "E1BMX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMX9" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 69, "end_pos": 139, "start_aa": "Ile", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 137, "end_pos": 139 }, { "start_pos": 650, "end_pos": 652 }, { "start_pos": 77, "end_pos": 79 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BMY4-1", "uniprot_ac": "E1BMY4", "uniprot_id": "E1BMY4_BOVIN", "mass": { "chemical_mass": 175635.0, "monoisotopic_mass": 175635.0 }, "refseq": {}, "gene_names": [ { "name": "CFAP74", "type": "recommended", "evidence": [ { "id": "E1BMY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMY4" } ] } ], "protein_names": [ { "name": "Cilia- and flagella-associated protein 74", "type": "recommended", "evidence": [ { "id": "E1BMY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMY4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "As part of the central apparatus of the cilium axoneme may play a role in cilium movement. May play an important role in sperm architecture and function.", "evidence": [ { "database": "UniProtKB", "id": "E1BMY4", "url": "https://www.uniprot.org/uniprotkb/E1BMY4#function" }, { "database": "UniProtKB", "id": "ARBA00053123", "url": "https://www.uniprot.org/uniprotkb/ARBA00053123#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMY4", "url": "https://www.uniprot.org/uniprotkb/E1BMY4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CFAP74", "url": "https://www.uniprot.org/uniprotkb/E1BMY4", "locus": { "chromosome": "16", "start_pos": 50830785, "end_pos": 50772970, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005231", "url": "https://www.ensembl.org/id/ENSBTAG00000005231" } ] } } ], "crossref": [ { "id": "ENSBTAG00000005231", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005231", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056306", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056306", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056307", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056307", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056310", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056310", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059255", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059255", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22538", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22538", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22538:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22538:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF24770", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24770", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24771", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24771", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24778", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24778", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24798", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24798", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BMY4", "url": "https://www.uniprot.org/uniprotkb/E1BMY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMY4-1", "url": "https://www.uniprot.org/uniprotkb/E1BMY4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEDDKKLLDDKPLVEDDTEELEDPELVLDCVPREAEQKAGLGSSCPGIEQSKDKQKQRLTAQEKRQACLLRRDLSHLDQLHEEKDLFIQKTRGELRACRRRMELLVKQQESVAAEIAAERAANNMAAMGRLEAASRRLCSELKNEQDLQAQMMAVLQQSQSALWQIEVQEGQLEDARKSAQEEAAAARRGLQERAAKQLHREMGASGKAERNRLLRARRCVHLQKELGLRQQKLVEEAQKNHRKALRFLKASLGRIREQEQKEELETREHMRRRMDAVLALKNSISANRETLRKFQAWGQAKTELAEQKAQAEKKAILAQGGDAFKHLCHQRRRQELEAQNRAFEEEQKRRKQEIVSRLLKEEAVEDRRRPRPEPPRPAGQRSLRDQTWSYVATFFDGQSTDQPDSQSSPLLTAISSESVQGDGSLGGEDTLAWPEIPGLWKEDYKPFQVSKEDVDRKPVGGTKMDKDILARTMQRLRSGVIHKQVASGREFRGCPFNSKPKFIHFKDFDVGKVYKKKITLINATYTINYCKLVGVDESLQDFIHVDFDPPGPLSAGMSCEVLVTFKPINKDLEGNVSFLAQTGGFSVPLKCSTKKCSLSLDKELIDFGSYTVGETAIRTITLTNTGGLGTKFRFLLASETCEMDTSQSVLKLSSTFTYEDKSLYDKFTTSFSEHQMEGNESSPTDVPSQKESGKLDVKEQEEGHPIESEGVTLTTIMTIPLNEEQMEFSLGETTEGDIGPFSSIKVPVIFTPIVPGTVQNSFKVVFKNQQCPTLYFKVVGVAIDVPVWVPKPNVDLKICMYDRLYQDSILVHTRSKAALRLKFEVCKELRGHVELLPETGYIQALSSYSVQLKFLPRHSLPEDAGKYFDKETRVLEAPMTIRVADQIKPVGFTVHAVVTTSDLELSPAGLDFGYCTIYEAIRTQISLCNHSLLPQEFGFVGLPKFVDIQPNDGFGTILPLETLQLDVIFQPTKAKEYNFELICKSEINRCFKLACRAVGVYPPLELSHNQIKFAATSLYDTSVATLYVINSHLSMNSLTHSVPRIGSEDAFPVGPTSFEFLLPPDSPITISPLVGTVWPGKRCLVRVAFRPVLPSELIHQEAFQALSRKAEVKSSQKETVTQRKDQRRPSFSMLRLQNQDRLLRASASQPPELQKEDLASSSQEYQSAQASLTRSFQGKFDKFVVPCVVASGDTKDRKGTEPLSFSPHNTLYLELWCPAVAPSIVVTSDKGKTIINFGDIAAGHRGIKKVSIQNISPEDLDLEYSVLNPDGPFVLLNPTIRLPSGETQVLDLSFSPRESVVAQEILDIITKKGTLSLALMGTGVASTITCSIEGDVLNMGYVIARESVSLGFKLQNNSPLPIKFSMQLDSLSSRSRDQHRLPQFLASPDQRTEVVGTQNYSGQSVFSVVPVEGVMEPGKAQDFTVTFSPDHESLYFSDRLQVVLFEKKVSHHILLKGAAREHMMFVEGGDPLDVPVESLTVIPAFDLEHREEAEELKPILVTLDYAQLDPDTQAPPATRELQVGCIRTTQLSAKKPDHPLLASALLQLRGDVKETYKVLFVAQVVTGP", "length": 1570, "header": "tr|E1BMY4-1|E1BMY4_BOVIN Isoform 1 of Cilia- and flagella-associated protein 74 OS=Bos taurus OX=9913 GN=CFAP74 PE=3 SV=4 CANONICAL=E1BMY4-1" }, "isoforms": [ { "isoform_ac": "E1BMY4-1", "url": "https://www.uniprot.org/uniprotkb/E1BMY4/entry", "sequence": { "sequence": "MEEDDKKLLDDKPLVEDDTEELEDPELVLDCVPREAEQKAGLGSSCPGIEQSKDKQKQRLTAQEKRQACLLRRDLSHLDQLHEEKDLFIQKTRGELRACRRRMELLVKQQESVAAEIAAERAANNMAAMGRLEAASRRLCSELKNEQDLQAQMMAVLQQSQSALWQIEVQEGQLEDARKSAQEEAAAARRGLQERAAKQLHREMGASGKAERNRLLRARRCVHLQKELGLRQQKLVEEAQKNHRKALRFLKASLGRIREQEQKEELETREHMRRRMDAVLALKNSISANRETLRKFQAWGQAKTELAEQKAQAEKKAILAQGGDAFKHLCHQRRRQELEAQNRAFEEEQKRRKQEIVSRLLKEEAVEDRRRPRPEPPRPAGQRSLRDQTWSYVATFFDGQSTDQPDSQSSPLLTAISSESVQGDGSLGGEDTLAWPEIPGLWKEDYKPFQVSKEDVDRKPVGGTKMDKDILARTMQRLRSGVIHKQVASGREFRGCPFNSKPKFIHFKDFDVGKVYKKKITLINATYTINYCKLVGVDESLQDFIHVDFDPPGPLSAGMSCEVLVTFKPINKDLEGNVSFLAQTGGFSVPLKCSTKKCSLSLDKELIDFGSYTVGETAIRTITLTNTGGLGTKFRFLLASETCEMDTSQSVLKLSSTFTYEDKSLYDKFTTSFSEHQMEGNESSPTDVPSQKESGKLDVKEQEEGHPIESEGVTLTTIMTIPLNEEQMEFSLGETTEGDIGPFSSIKVPVIFTPIVPGTVQNSFKVVFKNQQCPTLYFKVVGVAIDVPVWVPKPNVDLKICMYDRLYQDSILVHTRSKAALRLKFEVCKELRGHVELLPETGYIQALSSYSVQLKFLPRHSLPEDAGKYFDKETRVLEAPMTIRVADQIKPVGFTVHAVVTTSDLELSPAGLDFGYCTIYEAIRTQISLCNHSLLPQEFGFVGLPKFVDIQPNDGFGTILPLETLQLDVIFQPTKAKEYNFELICKSEINRCFKLACRAVGVYPPLELSHNQIKFAATSLYDTSVATLYVINSHLSMNSLTHSVPRIGSEDAFPVGPTSFEFLLPPDSPITISPLVGTVWPGKRCLVRVAFRPVLPSELIHQEAFQALSRKAEVKSSQKETVTQRKDQRRPSFSMLRLQNQDRLLRASASQPPELQKEDLASSSQEYQSAQASLTRSFQGKFDKFVVPCVVASGDTKDRKGTEPLSFSPHNTLYLELWCPAVAPSIVVTSDKGKTIINFGDIAAGHRGIKKVSIQNISPEDLDLEYSVLNPDGPFVLLNPTIRLPSGETQVLDLSFSPRESVVAQEILDIITKKGTLSLALMGTGVASTITCSIEGDVLNMGYVIARESVSLGFKLQNNSPLPIKFSMQLDSLSSRSRDQHRLPQFLASPDQRTEVVGTQNYSGQSVFSVVPVEGVMEPGKAQDFTVTFSPDHESLYFSDRLQVVLFEKKVSHHILLKGAAREHMMFVEGGDPLDVPVESLTVIPAFDLEHREEAEELKPILVTLDYAQLDPDTQAPPATRELQVGCIRTTQLSAKKPDHPLLASALLQLRGDVKETYKVLFVAQVVTGP", "length": 1570, "header": "tr|E1BMY4-1|E1BMY4_BOVIN Isoform 1 of Cilia- and flagella-associated protein 74 OS=Bos taurus OX=9913 GN=CFAP74 PE=3 SV=4 CANONICAL=E1BMY4-1" }, "locus": { "chromosome": "16", "start_pos": 50830782, "end_pos": 50772970, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006889.7", "url": "https://www.ensembl.org/id/ENSBTAT00000006889.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006889.7", "url": "https://www.ensembl.org/id/ENSBTAP00000006889.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1058, "start_aa": "Thr", "end_pos": 1058, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1058", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1256, "end_pos": 1258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1358, "end_pos": 1360, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1401, "end_pos": 1403, "annotation": "n_glycosylation_sequon" }, { "start_pos": 524, "end_pos": 526, "annotation": "n_glycosylation_sequon" }, { "start_pos": 577, "end_pos": 579, "annotation": "n_glycosylation_sequon" }, { "start_pos": 681, "end_pos": 683, "annotation": "n_glycosylation_sequon" }, { "start_pos": 931, "end_pos": 933, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BMY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMY4" }, { "id": "PF24771", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24771" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CFAP74 first Ig-like", "eco_id": "ECO_0000259", "start_pos": 498, "end_pos": 593, "start_aa": "Phe", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "E1BMY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMY4" }, { "id": "PF24798", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24798" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CFAP74 fourth Ig-like", "eco_id": "ECO_0000259", "start_pos": 908, "end_pos": 1002, "start_aa": "Ser", "end_aa": "Val", "glycosite_overlap": [] }, { "evidence": [ { "id": "E1BMY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMY4" }, { "id": "PF24770", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24770" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CFAP74 second Ig-like", "eco_id": "ECO_0000259", "start_pos": 600, "end_pos": 787, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": [] }, { "evidence": [ { "id": "E1BMY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMY4" }, { "id": "PF24778", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24778" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CFAP74 third Ig-like", "eco_id": "ECO_0000259", "start_pos": 789, "end_pos": 901, "start_aa": "Val", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1058 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1256, "end_pos": 1258 }, { "start_pos": 1358, "end_pos": 1360 }, { "start_pos": 1401, "end_pos": 1403 }, { "start_pos": 524, "end_pos": 526 }, { "start_pos": 577, "end_pos": 579 }, { "start_pos": 681, "end_pos": 683 }, { "start_pos": 931, "end_pos": 933 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BMY9-1", "uniprot_ac": "E1BMY9", "uniprot_id": "E1BMY9_BOVIN", "mass": { "chemical_mass": 124660.0, "monoisotopic_mass": 124660.0 }, "refseq": { "ac": "XP_024832312", "name": "WD repeat-containing protein 64 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832312" }, "gene_names": [ { "name": "WDR64", "type": "recommended", "evidence": [ { "id": "E1BMY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMY9" } ] }, { "name": "WDR64", "type": "synonym", "evidence": [ { "id": "XP_024832312", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832312" } ] } ], "protein_names": [ { "name": "WD repeat domain 64", "type": "synonym", "evidence": [ { "id": "E1BMY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMY9/entry#names_and_taxonomy" } ] }, { "name": "WD repeat-containing protein 64 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024832312", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832312" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMY9", "url": "https://www.uniprot.org/uniprotkb/E1BMY9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "WDR64", "url": "https://www.uniprot.org/uniprotkb/E1BMY9", "locus": { "chromosome": "16", "start_pos": 35010242, "end_pos": 35130360, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005200", "url": "https://www.ensembl.org/id/ENSBTAG00000005200" } ] } } ], "crossref": [ { "id": "E1BMY9", "url": "https://alphafold.ebi.ac.uk/entry/E1BMY9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005200", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005200", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "783230", "url": "https://www.ncbi.nlm.nih.gov/gene/783230", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:783230", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:783230", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BMY9", "url": "https://www.orthodb.org/?gene=E1BMY9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44324", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44324", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44324:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44324:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024832312", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832312", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SYX7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYX7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYX7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMY9", "url": "https://www.uniprot.org/uniprotkb/E1BMY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMY9-1", "url": "https://www.uniprot.org/uniprotkb/E1BMY9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDIREEKHINTALQVSSFRTALRGFERLVEHVAAQKRDERAGVFAPKEDAVDYDKFYKMVQELFGPEVKSQDVKCFYRKLCNNPDASIDWCEIFGYFSSEEDSLINQMDEENLVFLVSRKQRVVISGSRRRDVIKCIVKIPQLDLLITASQKGMITVFNSQMKVQTSTNVTDTSWITGCDYLSQLKRIVATTERTIIVWDYKAQGSSQENYFVIKPMDHCLLCVCVVSLPDQLCRDDILLGDDGGFVSKFTVNSEDFGLKQAKSKKRLQNQVLDSKNFKSVKRKLHNDWVMKIRYISALHCFGSCSLDNVHSLVLESLKRIEDNLPVREFSMPRGANTFCYCIKANVIVTGGDDKVLRLWHPNISTKPVGKLVGHMFSITEIVTNEKEQHVISLSSAKVFRVWDIQTLSLLQVFHDSQGGPGDMQIYSMIFDSNHRVLITGSSVMDMYPLTRMIQDTKQVPHTHEREINVMLYNKYFHQVLTICSESIIKVWELETGLQIYQILDPHGFNVELTAAAIDESGFIFATGAYNGTVKIWDFGSGQELKVLPEGKDWKEEEHWLHRLIFLKAQEKHQYLLLSLERNGKIKMIQGKEDDIYLAVIWELPDVVPVLQSGNRIVHLRVSTKERSMAIPFPDVELIVEKNFSQRVGNPAVSIEVNCIDLLQTEGYNLIAAGTLNGVIILWNFVTSTVKEVYRPEDCFTVDPDLDPKRFRINDILFLFRNPECVRRSSQDSVCSSSQCDSSKGPQSSKGSKQSIHESELKGEQTDVAVREQQPVDKKPPGGTNETDAQPPPILVTAHEDGHLRLWTMEGRLLKDILPFTKHAAISLTSLFTDSCTRILLTGNTEGHVILCNISSFLESPHDEKKFKQLLAWRAHSLEIVQIIYVEEKQVVLTASIDGSVRLWHALNGHYCGYFGQRRTFELSQTSDFILPCDVTEYPIEIKEESKFTEKKLTYEYPLVFDRQRWQKMSSMSLLFKRTPPKAFEVEHDFKFFKSLSSPKIRKHALEGFMTENREAGIVFGSLPIYRVPSPTSLRFLPLIGSEAQRESSDGIHGKKKGSHVQHEKVQRRRSLKRNLVPQVNLASSFFPAIPK", "length": 1092, "header": "tr|E1BMY9-1|E1BMY9_BOVIN Isoform 1 of WD repeat domain 64 OS=Bos taurus OX=9913 GN=WDR64 PE=4 SV=2 CANONICAL=E1BMY9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SYX7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYX7/entry", "sequence": { "sequence": "MDIREEKHINTALQVSSFRTALRGFERLVEHVAAQKRDERAGVFAPKEDAVDYDKFYKMVQELFGPEVKSQDVKCFYRKLCNNPDASIDWCEIFGYFSSEEDSLINQMDEENLVFLVSRKQRVVISGSRRRDVIKCIVKIPQLDLLITASQKGMITVFNSQDTSWITGCDYLSQLKRIVATTERTIIVWDYKAQGSSQENYFVIKPMDHCLLCVCVVSLPDQLCRDDILLGDDGGFVSKFTVNSEDFGLKQAKSKKRLQNQVLDSKNFKSVKRKLHNDWVMKIRYISALHCFGSCSLDNVHSLVLESLKRIEDNLPVREFSMPRGANTFCYCIKANVIVTGGDDKVLRLWHPNISTKPVGKLVGHMFSITEIVTNEKEQHVISLSSAKVFRVWDIQTLSLLQVFHDSQGGPGDMQIYSMIFDSNHRVLITGSSVMDMYPLTRMIQDTKQVPHTHEREINVMLYNKYFHQVLTICSESIIKVWELETGLQIYQILDPHGFNVELTAAAIDESGFIFATGAYNGTVKIWDFGSGQELKVLPEGKDWKEEEHWLHRLIFLKAQEKHQYLLLSLERNGKIKMIQGKEDDIYLAVIWELPDVVPVLQSGNRIVHLRVSTKERSMAIPFPDVELIVEKNFSQRVGNPAVSIEVNCIDLLQTEGYNLIAAGTLNGVIILWNFVTSTVKEVYRPEDCFTVDPDLDPKRFRINDILFLFRNPECVRRSSQDSVCSSSQCDSSKGPQSSKGSKQSIHESELKGEQTDVAVREQQPVDKKPPGGTNETDAQPPPILVTAHEDGHLRLWTMEGRLLKDILPFTKHAAISLTSLFTDSCTRILLTGNTEGHVILCNISSFLESPHDEKKFKQLLAWRAHSLEIVQIIYVEEKQVVLTASIDGSVRLWHALNGHYCGYFGQRRTFELSQTSDFILPCDVTEYPIEIKEESKFTEKKLTYEYPLVFDRQRWQKMSSMSLLFKRTPPKAFEVEHDFKFFKSLSSPKIRKHALEGFMTENREAGIVFGSLPIYRVPSPTSLRFLPLIGSEAQRESSDGIHGKKKGSHVQHEKVQRRRSLKRNLVPQVNLASSFFPAIPK", "length": 1082, "header": "tr|A0AAA9SYX7-1|A0AAA9SYX7_BOVIN Computationally mapped isoform of WD repeat domain 64 OS=Bos taurus OX=9913 GN=WDR64 PE=4 SV=2 CANONICAL=E1BMY9-1" }, "locus": { "chromosome": "16", "start_pos": 35130360, "end_pos": 35010245, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127721.2", "url": "https://www.ensembl.org/id/ENSBTAT00000127721.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091662.2", "url": "https://www.ensembl.org/id/ENSBTAP00000091662.2" } ] } }, { "isoform_ac": "E1BMY9-1", "url": "https://www.uniprot.org/uniprotkb/E1BMY9/entry", "sequence": { "sequence": "MDIREEKHINTALQVSSFRTALRGFERLVEHVAAQKRDERAGVFAPKEDAVDYDKFYKMVQELFGPEVKSQDVKCFYRKLCNNPDASIDWCEIFGYFSSEEDSLINQMDEENLVFLVSRKQRVVISGSRRRDVIKCIVKIPQLDLLITASQKGMITVFNSQMKVQTSTNVTDTSWITGCDYLSQLKRIVATTERTIIVWDYKAQGSSQENYFVIKPMDHCLLCVCVVSLPDQLCRDDILLGDDGGFVSKFTVNSEDFGLKQAKSKKRLQNQVLDSKNFKSVKRKLHNDWVMKIRYISALHCFGSCSLDNVHSLVLESLKRIEDNLPVREFSMPRGANTFCYCIKANVIVTGGDDKVLRLWHPNISTKPVGKLVGHMFSITEIVTNEKEQHVISLSSAKVFRVWDIQTLSLLQVFHDSQGGPGDMQIYSMIFDSNHRVLITGSSVMDMYPLTRMIQDTKQVPHTHEREINVMLYNKYFHQVLTICSESIIKVWELETGLQIYQILDPHGFNVELTAAAIDESGFIFATGAYNGTVKIWDFGSGQELKVLPEGKDWKEEEHWLHRLIFLKAQEKHQYLLLSLERNGKIKMIQGKEDDIYLAVIWELPDVVPVLQSGNRIVHLRVSTKERSMAIPFPDVELIVEKNFSQRVGNPAVSIEVNCIDLLQTEGYNLIAAGTLNGVIILWNFVTSTVKEVYRPEDCFTVDPDLDPKRFRINDILFLFRNPECVRRSSQDSVCSSSQCDSSKGPQSSKGSKQSIHESELKGEQTDVAVREQQPVDKKPPGGTNETDAQPPPILVTAHEDGHLRLWTMEGRLLKDILPFTKHAAISLTSLFTDSCTRILLTGNTEGHVILCNISSFLESPHDEKKFKQLLAWRAHSLEIVQIIYVEEKQVVLTASIDGSVRLWHALNGHYCGYFGQRRTFELSQTSDFILPCDVTEYPIEIKEESKFTEKKLTYEYPLVFDRQRWQKMSSMSLLFKRTPPKAFEVEHDFKFFKSLSSPKIRKHALEGFMTENREAGIVFGSLPIYRVPSPTSLRFLPLIGSEAQRESSDGIHGKKKGSHVQHEKVQRRRSLKRNLVPQVNLASSFFPAIPK", "length": 1092, "header": "tr|E1BMY9-1|E1BMY9_BOVIN Isoform 1 of WD repeat domain 64 OS=Bos taurus OX=9913 GN=WDR64 PE=4 SV=2 CANONICAL=E1BMY9-1" }, "locus": { "chromosome": "16", "start_pos": 35130360, "end_pos": 35010245, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000034164.5", "url": "https://www.ensembl.org/id/ENSBTAT00000034164.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000034065.4", "url": "https://www.ensembl.org/id/ENSBTAP00000034065.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:783230", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:783230", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 531, "end_pos": 533, "annotation": "n_glycosylation_sequon" }, { "start_pos": 643, "end_pos": 645, "annotation": "n_glycosylation_sequon" }, { "start_pos": 785, "end_pos": 787, "annotation": "n_glycosylation_sequon" }, { "start_pos": 853, "end_pos": 855, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMY9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1092, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMY9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMY9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 169, "end_pos": 171 }, { "start_pos": 363, "end_pos": 365 }, { "start_pos": 531, "end_pos": 533 }, { "start_pos": 643, "end_pos": 645 }, { "start_pos": 785, "end_pos": 787 }, { "start_pos": 853, "end_pos": 855 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BMZ4-1", "uniprot_ac": "E1BMZ4", "uniprot_id": "E1BMZ4_BOVIN", "mass": { "chemical_mass": 54549.0, "monoisotopic_mass": 54549.0 }, "refseq": { "ac": "XP_010800943", "name": "zinc finger protein 436 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010800943" }, "gene_names": [ { "name": "ZNF436", "type": "recommended", "evidence": [ { "id": "E1BMZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMZ4" } ] }, { "name": "ZNF436", "type": "synonym", "evidence": [ { "id": "XP_010800943", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010800943" } ] } ], "protein_names": [ { "name": "Zinc finger protein 436", "type": "recommended", "evidence": [ { "id": "E1BMZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMZ4/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 436 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_010800943", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010800943" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BMZ4", "url": "https://www.uniprot.org/uniprotkb/E1BMZ4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZNF436", "url": "https://www.uniprot.org/uniprotkb/E1BMZ4", "locus": { "chromosome": "2", "start_pos": 129484458, "end_pos": 129477138, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002594", "url": "https://www.ensembl.org/id/ENSBTAG00000002594" } ] } } ], "crossref": [ { "id": "E1BMZ4", "url": "https://alphafold.ebi.ac.uk/entry/E1BMZ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002594", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002594", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "525080", "url": "https://www.ncbi.nlm.nih.gov/gene/525080", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EAHTGIR", "url": "https://omabrowser.org/oma/group/EAHTGIR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BMZ4", "url": "https://www.orthodb.org/?gene=E1BMZ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF142", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF142", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF152", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF152", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_010800943", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010800943", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TTN0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTN0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTN0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMZ4", "url": "https://www.uniprot.org/uniprotkb/E1BMZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMZ4-1", "url": "https://www.uniprot.org/uniprotkb/E1BMZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAATLLMAGSQAPVTFEDMAMYLTREEWRPLDPTQRDIYRDVMQENYGNVVSLDFEIRSENEVNPKQEISEDVEFETASERPVGNTEENPESEEAFDNRDRSERQWGDLTAEEWVSYPLQQVTDLLVHKEVHTSIRYHICSHCGKAFSQISDLNRHQKTHTGDRPYKCYECGKGFSRSSHLIQHQRTHTGERPYDCNECGKSFGRSSHLIQHQTIHTGEKPHKCNECGKSFCRLSHLIQHQRTHSGEKPYECEECGKSFSRSSHLAQHQRTHTGEKPYECNECGRGFSERSDLIKHYRVHTGERPYKCDECGKNFSQNSDLVRHRRAHTGEKPYHCNECGENFSRISHLVQHQRTHTGEKPYECNACGKSFSRSSHLITHQKIHTGEKPYECNECWRSFGERSDLIKHQRTHTGEKPYECVQCGKGFTQSSNLITHQRVHTGEKPYECTECEKSFSRSSALIKHKRVHTD", "length": 470, "header": "tr|E1BMZ4-1|E1BMZ4_BOVIN Isoform 1 of Zinc finger protein 436 OS=Bos taurus OX=9913 GN=ZNF436 PE=3 SV=1 CANONICAL=E1BMZ4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TTN0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTN0/entry", "sequence": { "sequence": "MEEQRRSVGWAESLLPERTSRCLLAAFPALSPGRRILEPEMAATLLMAGSQAPVTFEDMAMYLTREEWRPLDPTQRDIYRDVMQENYGNVVSLDFEIRSENEVNPKQEISEDVEFETASERPVGNTEENPESEEAFDNRDRSERQWGDLTAEEWVSYPLQQVTDLLVHKEVHTSIRYHICSHCGKAFSQISDLNRHQKTHTGDRPYKCYECGKGFSRSSHLIQHQRTHTGERPYDCNECGKSFGRSSHLIQHQTIHTGEKPHKCNECGKSFCRLSHLIQHQRTHSGEKPYECEECGKSFSRSSHLAQHQRTHTGEKPYECNECGRGFSERSDLIKHYRVHTGERPYKCDECGKNFSQNSDLVRHRRAHTGEKPYHCNECGENFSRISHLVQHQRTHTGEKPYECNACGKSFSRSSHLITHQKIHTGEKPYECNECWRSFGERSDLIKHQRTHTGEKPYECVQCGKGFTQSSNLITHQRVHTGEKPYECTECEKSFSRSSALIKHKRVHTD", "length": 510, "header": "tr|A0AAA9TTN0-1|A0AAA9TTN0_BOVIN Computationally mapped isoform of Zinc finger protein 436 OS=Bos taurus OX=9913 GN=ZNF436 PE=3 SV=1 CANONICAL=E1BMZ4-1" }, "locus": { "chromosome": "2", "start_pos": 129483454, "end_pos": 129478288, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094448.2", "url": "https://www.ensembl.org/id/ENSBTAT00000094448.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101713.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101713.1" } ] } }, { "isoform_ac": "E1BMZ4-1", "url": "https://www.uniprot.org/uniprotkb/E1BMZ4/entry", "sequence": { "sequence": "MAATLLMAGSQAPVTFEDMAMYLTREEWRPLDPTQRDIYRDVMQENYGNVVSLDFEIRSENEVNPKQEISEDVEFETASERPVGNTEENPESEEAFDNRDRSERQWGDLTAEEWVSYPLQQVTDLLVHKEVHTSIRYHICSHCGKAFSQISDLNRHQKTHTGDRPYKCYECGKGFSRSSHLIQHQRTHTGERPYDCNECGKSFGRSSHLIQHQTIHTGEKPHKCNECGKSFCRLSHLIQHQRTHSGEKPYECEECGKSFSRSSHLAQHQRTHTGEKPYECNECGRGFSERSDLIKHYRVHTGERPYKCDECGKNFSQNSDLVRHRRAHTGEKPYHCNECGENFSRISHLVQHQRTHTGEKPYECNACGKSFSRSSHLITHQKIHTGEKPYECNECWRSFGERSDLIKHQRTHTGEKPYECVQCGKGFTQSSNLITHQRVHTGEKPYECTECEKSFSRSSALIKHKRVHTD", "length": 470, "header": "tr|E1BMZ4-1|E1BMZ4_BOVIN Isoform 1 of Zinc finger protein 436 OS=Bos taurus OX=9913 GN=ZNF436 PE=3 SV=1 CANONICAL=E1BMZ4-1" }, "locus": { "chromosome": "2", "start_pos": 129483454, "end_pos": 129478645, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003359.6", "url": "https://www.ensembl.org/id/ENSBTAT00000003359.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003359.3", "url": "https://www.ensembl.org/id/ENSBTAP00000003359.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1VYW8-1", "protein_name": "Zinc finger protein 436", "gene_name": "ZNF436", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAATLLMAGSQAPVTFEDMAMYLTREEWRPLDPTQRDLYRDVMQENYGNVVSLDFEIRSENEVNPKQEISEDVEFGTVSERPVGNTEENPESEEAFENRDRSERQWGDLTAEEWVNYPLQQVTDLLVHKEVHTSIRYHICSHCGKAFSQISDLNRHQKTHTGDRPYKCYECGKGFSRSSHLIQHQRTHTGERPYDCNECGKSFGRSSHLIQHQTIHTGEKPHKCNECGKSFCRLSHLIQHQRTHSGEKPYECEECGKSFSRSSHLAQHQRTHTGEKPYECNECGRGFSERSDLIKHYRVHTGERPYKCDECGKNFSQNSDLVRHRRAHTGEKPYHCNECGENFSRISHLVQHQRTHTGEKPYECNACGKSFSRSSHLITHQKIHTGEKPYECNECWRSFGERSDLIKHQRTHTGEKPYECVQCGKGFTQSSNLITHQRVHTGEKPYECTECEKSFSRSSALIKHKRVHTD", "length": 470 }, "evidence": [ { "id": "E1BMZ4", "url": "https://omabrowser.org/oma/group/E1BMZ4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6GFA5-1", "protein_name": "Zinc finger protein 436", "gene_name": "Zfp46", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMFLTREEWRPLDPTQRDLYRDVMQENYGNVVSLDFEIRSENEANPKQEFSDDVEFATMSEEPLENAEKNPGSEEAFESGDRSERPWGDLTAEEWVSYPLQQVTDLLVHKEAHTGIRYHICSQCGKAFSQISDLNRHQKTHTGDRPYKCYECGKGFSRSSHLIQHQRTHTGERPYDCNECGKSFGRSSHLIQHQTIHTGEKPHKCTECGKSFCRLSHLIQHQRTHSGEKPYECEECGKSFSRSSHLAQHQRTHTGEKPYECNECGRGFSERSDLIKHYRVHTGERPYKCDECGKNFSQNSDLVRHRRAHTGEKPYHCNECGENFSRISHLVQHQRTHTGEKPYECTACGKSFSRSSHLITHQKIHTGEKPYECTECWRSFGERSDLIKHQRTHTGEKPYECVQCGKGFTQSSNLITHQRVHTGEKPYECTECDKSFSRSSALIKHKRVHTD", "length": 452 }, "evidence": [ { "id": "E1BMZ4", "url": "https://omabrowser.org/oma/group/E1BMZ4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BPP0-1", "protein_name": "Zinc finger protein 436", "gene_name": "Znf436", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAMYLTREEWRPLDPTQRDLYRDVMQENYGNVVSLDFEIRSENEANPKQEFSDDVEFATMSEEPLENAEKNPGSEEAFESGDQAERPWGDLTAEEWVSYPLQQVTDLLVHKEAHAGIRYHICSQCGKAFSQISDLNRHQKTHTGDRPYKCYECGKGFSRSSHLIQHQRTHTGERPYDCNECGKSFGRSSHLIQHQTIHTGEKPHKCTECGKSFCRLSHLIQHQRTHSGEKPYECEECGKSFSRSSHLAQHQRTHTGEKPYECHECGRGFSERSDLIKHYRVHTGERPYKCDECGKNFSQNSDLVRHRRAHTGEKPYHCNECGENFSRISHLVQHQRTHTGEKPYECTACGKSFSRSSHLITHQKIHTGEKPYECNECWRSFGERSDLIKHQRTHTGEKPYECVQCGKGFTQSSNLITHQRVHTGEKPYECTECDKSFSRSSALIKHKRVHTD", "length": 452 }, "evidence": [ { "id": "E1BMZ4", "url": "https://omabrowser.org/oma/group/E1BMZ4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C0F3-1", "protein_name": "Zinc finger protein 436", "gene_name": "ZNF436", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAATLLMAGSQAPVTFEDMAMYLTREEWRPLDAAQRDLYRDVMQENYGNVVSLDFEIRSENEVNPKQEISEDVQFGTTSERPAENAEENPESEEGFESGDRSERQWGDLTAEEWVSYPLQPVTDLLVHKEVHTGIRYHICSHCGKAFSQISDLNRHQKTHTGDRPYKCYECGKGFSRSSHLIQHQRTHTGERPYDCNECGKSFGRSSHLIQHQTIHTGEKPHKCNECGKSFCRLSHLIQHQRTHSGEKPYECEECGKSFSRSSHLAQHQRTHTGEKPYECNECGRGFSERSDLIKHYRVHTGERPYKCDECGKNFSQNSDLVRHRRAHTGEKPYHCNECGENFSRISHLVQHQRTHTGEKPYECNACGKSFSRSSHLITHQKIHTGEKPYECNECWRSFGERSDLIKHQRTHTGEKPYECVQCGKGFTQSSNLITHQRVHTGEKPYECTECEKSFSRSSALIKHKRVHTD", "length": 470 }, "evidence": [ { "id": "E1BMZ4", "url": "https://omabrowser.org/oma/group/E1BMZ4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BMZ4", "url": "https://www.uniprot.org/uniprotkb/E1BMZ4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BMZ4", "url": "https://www.uniprot.org/uniprotkb/E1BMZ4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BMZ4", "url": "https://www.uniprot.org/uniprotkb/E1BMZ4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BMZ4", "url": "https://www.uniprot.org/uniprotkb/E1BMZ4" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "E1BMZ4", "url": "https://www.uniprot.org/uniprotkb/E1BMZ4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BMZ4", "url": "https://www.uniprot.org/uniprotkb/E1BMZ4" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "E1BMZ4", "url": "https://www.uniprot.org/uniprotkb/E1BMZ4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BMZ4", "url": "https://www.uniprot.org/uniprotkb/E1BMZ4" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BMZ4", "url": "https://www.uniprot.org/uniprotkb/E1BMZ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 314, "end_pos": 316, "annotation": "n_glycosylation_sequon" }, { "start_pos": 342, "end_pos": 344, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BMZ4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 470, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BMZ4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BMZ4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BMZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMZ4" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 138, "end_pos": 165, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "E1BMZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMZ4" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 85, "start_aa": "Val", "end_aa": "Asn", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 314, "end_pos": 316 }, { "start_pos": 342, "end_pos": 344 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BN13-1", "uniprot_ac": "E1BN13", "uniprot_id": "E1BN13_BOVIN", "mass": { "chemical_mass": 40680.0, "monoisotopic_mass": 40680.0 }, "refseq": { "ac": "NP_001179058", "name": "uS5 assembly chaperone PDCD2L", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179058" }, "gene_names": [ { "name": "PDCD2L", "type": "recommended", "evidence": [ { "id": "E1BN13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN13" } ] }, { "name": "PDCD2L", "type": "synonym", "evidence": [ { "id": "NP_001179058", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179058" } ] } ], "protein_names": [ { "name": "Programmed cell death 2 like", "type": "synonym", "evidence": [ { "id": "E1BN13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN13/entry#names_and_taxonomy" } ] }, { "name": "uS5 assembly chaperone PDCD2L", "type": "synonym", "evidence": [ { "id": "NP_001179058", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179058" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BN13", "url": "https://www.uniprot.org/uniprotkb/E1BN13" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PDCD2L", "url": "https://www.uniprot.org/uniprotkb/E1BN13", "locus": { "chromosome": "18", "start_pos": 44835839, "end_pos": 44817570, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002571", "url": "https://www.ensembl.org/id/ENSBTAG00000002571" } ] } } ], "crossref": [ { "id": "E1BN13", "url": "https://alphafold.ebi.ac.uk/entry/E1BN13", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002571", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002571", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "507032", "url": "https://www.ncbi.nlm.nih.gov/gene/507032", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052815", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052815", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:507032", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507032", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EECALVQ", "url": "https://omabrowser.org/oma/group/EECALVQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BN13", "url": "https://www.orthodb.org/?gene=E1BN13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46421", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46421", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46421:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46421:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04194", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04194", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179058", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179058", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BN13", "url": "https://www.uniprot.org/uniprotkb/E1BN13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN13-1", "url": "https://www.uniprot.org/uniprotkb/E1BN13-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAVRKPVLLGLRDAAVHGRPTGPSAWTASKLGGVPDALPAVAAPRPVCELCRQPLALVVQVYCPLEGSPFHRLLHVFACPRPECGSGGARSWKVFRSQCLQMREKETQDAQKQENGLTAEDWCEGADDWGSDSEEASPLQPVSEFGNDLSNAKDRDWTSQLQDLRLQDTVPGVAPPAPPGGGPALPPSVPQFLPYYICVVDEDDYTDFISLDHAQSLLREYQQREGVDMEQLLSQSLSSDGDEKYEKTVIKSGDKMFYKFMKRIAACQEQILRYSWSGEPLFLTCPTSEVTELPACSYCGARRIFEFQLMPALVSMLRSANLDLSVEFGTILIYTCEKSCWPQNDQAPMEEFCIIQEDPDELLFK", "length": 366, "header": "tr|E1BN13-1|E1BN13_BOVIN Isoform 1 of Programmed cell death 2 like OS=Bos taurus OX=9913 GN=PDCD2L PE=3 SV=1 CANONICAL=E1BN13-1" }, "isoforms": [ { "isoform_ac": "E1BN13-1", "url": "https://www.uniprot.org/uniprotkb/E1BN13/entry", "sequence": { "sequence": "MAAVRKPVLLGLRDAAVHGRPTGPSAWTASKLGGVPDALPAVAAPRPVCELCRQPLALVVQVYCPLEGSPFHRLLHVFACPRPECGSGGARSWKVFRSQCLQMREKETQDAQKQENGLTAEDWCEGADDWGSDSEEASPLQPVSEFGNDLSNAKDRDWTSQLQDLRLQDTVPGVAPPAPPGGGPALPPSVPQFLPYYICVVDEDDYTDFISLDHAQSLLREYQQREGVDMEQLLSQSLSSDGDEKYEKTVIKSGDKMFYKFMKRIAACQEQILRYSWSGEPLFLTCPTSEVTELPACSYCGARRIFEFQLMPALVSMLRSANLDLSVEFGTILIYTCEKSCWPQNDQAPMEEFCIIQEDPDELLFK", "length": 366, "header": "tr|E1BN13-1|E1BN13_BOVIN Isoform 1 of Programmed cell death 2 like OS=Bos taurus OX=9913 GN=PDCD2L PE=3 SV=1 CANONICAL=E1BN13-1" }, "locus": { "chromosome": "18", "start_pos": 44835778, "end_pos": 44817604, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003327.6", "url": "https://www.ensembl.org/id/ENSBTAT00000003327.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003327.5", "url": "https://www.ensembl.org/id/ENSBTAP00000003327.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:507032", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507032", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q9VG62-1", "protein_name": "Toys are us", "gene_name": "trus", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAKNKSTVYLGYEDEEVTAKQEQLLNSCTNKIGGTPDWPRHEVTIPSCPLCGAVRPLIVQMYAPLDRSQFHRSLYVFGCMNPVCSQNSKSWCCVRTQHLDHQYEVISEHSPKATPTKKQNSKKKGKSSGLQAISWCSGADDWGDSSGGATEQAKTISVALDEAMDITADDDQNERNGNVRPNALQYAKSDIQIDEPAKLEQVKIAADDDDDEDESTSLENELISGFHQMDMISPQNADDDPNANCAAAAAPSLDGAGASAASAAIGAEIEGPETDLVLVDTPKKPERDLIALLKHTSGALSQIKDLTLKSYYIAVDVENKTQAEEYENFGGALSMDHIRDLYQEYKLRDQNPGQSPTGGASGPGEQGDENESYEKALPAHGDLVFHNFITTIHQNPGQLLRYSRDTIPLLVAPFTEPLPKCQNCRGETICEVQLLPTLIPKLRFQVNGCNAPIEFGNVLVFTCLKSCWDTPDLMRYEHIVVQSET", "length": 485 }, "evidence": [ { "id": "E1BN13", "url": "https://omabrowser.org/oma/group/E1BN13/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BN13", "url": "https://www.uniprot.org/uniprotkb/E1BN13" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "E1BN13", "url": "https://www.uniprot.org/uniprotkb/E1BN13" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BN13-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 366, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BN13-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BN13" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BN13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN13" }, { "id": "PF04194", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04194" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Programmed cell death protein 2 C-terminal", "eco_id": "ECO_0000259", "start_pos": 255, "end_pos": 358, "start_aa": "Asp", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BN16-1", "uniprot_ac": "E1BN16", "uniprot_id": "E1BN16_BOVIN", "mass": { "chemical_mass": 169858.0, "monoisotopic_mass": 169858.0 }, "refseq": { "ac": "XP_005204380", "name": "coiled-coil domain-containing protein 18 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005204380" }, "gene_names": [ { "name": "CCDC18", "type": "recommended", "evidence": [ { "id": "E1BN16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN16" } ] }, { "name": "CCDC18", "type": "synonym", "evidence": [ { "id": "XP_005204380", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005204380" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 18", "type": "synonym", "evidence": [ { "id": "E1BN16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN16/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 18 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005204380", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005204380" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BN16", "url": "https://www.uniprot.org/uniprotkb/E1BN16" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CCDC18", "url": "https://www.uniprot.org/uniprotkb/E1BN16", "locus": { "chromosome": "3", "start_pos": 50120033, "end_pos": 50290098, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000027321", "url": "https://www.ensembl.org/id/ENSBTAG00000027321" } ] } } ], "crossref": [ { "id": "ENSBTAG00000027321", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000027321", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "540863", "url": "https://www.ncbi.nlm.nih.gov/gene/540863", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "bta:540863", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540863", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SKQPWES", "url": "https://omabrowser.org/oma/group/SKQPWES/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BN16", "url": "https://www.orthodb.org/?gene=E1BN16", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18875", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18875", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18875:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18875:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_005204380", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005204380", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SRV5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SRV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SRV5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SRV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN16", "url": "https://www.uniprot.org/uniprotkb/E1BN16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN16-1", "url": "https://www.uniprot.org/uniprotkb/E1BN16-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESSSSDFYNKDNEEESLLANVASLRHELKITEWSLQSLGEELSSVSPSENSDYAPNLSRSERLILENLSHPSHLGLLNYSPHNRVCKMPNSGTDFQKKPRDKMSFSSSTPVDQEIKSLREKLNKLRQQNACLVSQNHSLMTKIESVHFELTQSRAKVSMLESAQKQAANVPILEEQIINLEAEVSAQDKVLREAEDKLEQSQKMVIEKEQSLQKSQEECIRLKVDLLEQSKQGKRAERQRNEALYNAEELSKAFQHYKEKVAEKLEKVQAEEEILEKNLINCEKENKRLQEKCGLYKNELEILKEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESDLEDKDEILREKFSLMNENRELKVRIATQNERLDLCQQEIESSRVELRSLEKIMSQLPLKREIFGFKSPLSKHQMSSLSNKQDSYIGCCETNKMVISELRIKLAIKEAEIQKLQANLTANQLSHNLTACNDYQEGRKLNSLEIEPVKLGNQVESLKDQNQHTMNKQYERERQRLASGIEELRDKLMQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLDQHKEMEKQIERLESQLDKKEQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMEKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELALHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETAEQNVILQHTLQQQQQMLQQETIRNEELEDIQTKLEKQISKLEQELQKQRESSAEKLRKMEEKCEAATYEADLKRQKIIELTGTTRQVKLEMDQYKEELSKMEKEIMHLKRDGENKAMHVSQLDMILEQTKTELDKKTNAVKDLEKLQHHTETELTEALQKREALETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIRGHRGEMEQKIIKLEGTVEKSELELKESSRQIESLNEKLQNSKEQLREKEFITLQNEQEISQLKKETERTQQKMKEMESVMKEQEQYIATQYKEAIDLEQELRLTREQMQNSHKELVEARHQQVQAQREIERLSSELEEIKQLSKEKEAHGKYLAEELGASQVRETQLEARMQAEIKKLSTEVESLKEAYHLEMISHQENHAKWKISVDSQKTSVQQLNEQLEKAKLELEEAQDTVSSLHQQVQDRNEVIEATNEALLIKESELTRLQAKISGHERAEDIKFLPAPFTSPVEITPDIQDSKLAKHSHTAFFKCRKLRRSISASDLSFRTHSDEDLSEELLQDLKKMQLEQPSTLEENQRDLPYTQSDSFKPLTYDLNDDNSENNDFSTLSGMLRYINKEVRLLKKSSMQTGAGSTQGENL", "length": 1456, "header": "tr|E1BN16-1|E1BN16_BOVIN Isoform 1 of Coiled-coil domain containing 18 OS=Bos taurus OX=9913 GN=CCDC18 PE=4 SV=3 CANONICAL=E1BN16-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SRV5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SRV5/entry", "sequence": { "sequence": "MTLKLPFCLLPNWGEKSLTCQMPEGEGGSACLHLLVSTTEPEHHVVQDCFSLKVCSALVGLIRLFFFIFQMSFSSSTPVDQEIKSLREKLNKLRQQNACLVSQNHSLMTKIESVHFELTQSRAKVSMLESAQKQAANVPILEEQIINLEAEVSAQDKVLREAEDKLEQSQKMVIEKEQSLQKSQEECIRLKVDLLEQSKQGKRAERQRNEALYNAEELSKAFQHYKEKVAEKLEKVQAEEEILEKNLINCEKENKRLQEKCGLYKNELEILKEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESDLEDKDEILREKFSLMNENRELKVRIATQNERLDLCQQEIESSRVELRSLEKIMSQLPLKREIFGFKSPLSKHQMSSLSNKQDSYIGCCETNKMVISELRIKLAIKEAEIQKLQANLTANQLSHNLTACNDYQEGRKLNSLEIEPVKLGNQVESLKDQNQHTMNKQYERERQRLASGIEELRDKLMQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLDQHKEMEKQIERLESQLDKKEQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMEKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELALHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETAEQNVILQHTLQQQQQMLQQETIRNEELEDIQTKLEKQISKLEQELQKQRESSAEKLRKMEEKCEAATYEADLKRQKIIELTGTTRQVKLEMDQYKEELSKMEKEIMHLKRDGENKAMHVSQLDMILEQTKTELDKKTNAVKDLEKLQHHTETELTEALQKREALETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIRGHRGEMEQKIIKLEGTVEKSELELKESSRQIESLNEKLQNSKEQLREKEFITLQNEQEISQLKKETERTQQKMKEMESVMKEQEQYIATQYKEAIDLEQELRLTREQMQNSHKELVEARHQQVQAQREIERLSSELEEIKQLSKEKEAHGKYLAEELGASQVRETQLEARMQAEIKKLSTEVESLKEAYHLEMISHQENHAKWKISVDSQKTSVQQLNEQLEKAKLELEEAQDTVSSLHQQVQDRNEVIEATNEALLIKESELTRLQAKISGHERAEDIKFLPAPFTSPVEITPDIQDSKLAKHSHTAFFKCRKLRRSISASDLSFRTHSDEDLSEELLQDLKKMQLEQPSTLEENQRDLPYTQSDSFKPLTYDLNDDNSENNDFSTLSGMLRYINKEVRLLKKSSMQTGAGSTQGENL", "length": 1423, "header": "tr|A0AAA9SRV5-1|A0AAA9SRV5_BOVIN Computationally mapped isoform of Coiled-coil domain containing 18 OS=Bos taurus OX=9913 GN=CCDC18 PE=4 SV=1 CANONICAL=E1BN16-1" }, "locus": { "chromosome": "3", "start_pos": 50281139, "end_pos": 50177594, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127836.1", "url": "https://www.ensembl.org/id/ENSBTAT00000127836.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085718.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085718.1" } ] } }, { "isoform_ac": "E1BN16-1", "url": "https://www.uniprot.org/uniprotkb/E1BN16/entry", "sequence": { "sequence": "MESSSSDFYNKDNEEESLLANVASLRHELKITEWSLQSLGEELSSVSPSENSDYAPNLSRSERLILENLSHPSHLGLLNYSPHNRVCKMPNSGTDFQKKPRDKMSFSSSTPVDQEIKSLREKLNKLRQQNACLVSQNHSLMTKIESVHFELTQSRAKVSMLESAQKQAANVPILEEQIINLEAEVSAQDKVLREAEDKLEQSQKMVIEKEQSLQKSQEECIRLKVDLLEQSKQGKRAERQRNEALYNAEELSKAFQHYKEKVAEKLEKVQAEEEILEKNLINCEKENKRLQEKCGLYKNELEILKEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESDLEDKDEILREKFSLMNENRELKVRIATQNERLDLCQQEIESSRVELRSLEKIMSQLPLKREIFGFKSPLSKHQMSSLSNKQDSYIGCCETNKMVISELRIKLAIKEAEIQKLQANLTANQLSHNLTACNDYQEGRKLNSLEIEPVKLGNQVESLKDQNQHTMNKQYERERQRLASGIEELRDKLMQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLDQHKEMEKQIERLESQLDKKEQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMEKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELALHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETAEQNVILQHTLQQQQQMLQQETIRNEELEDIQTKLEKQISKLEQELQKQRESSAEKLRKMEEKCEAATYEADLKRQKIIELTGTTRQVKLEMDQYKEELSKMEKEIMHLKRDGENKAMHVSQLDMILEQTKTELDKKTNAVKDLEKLQHHTETELTEALQKREALETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIRGHRGEMEQKIIKLEGTVEKSELELKESSRQIESLNEKLQNSKEQLREKEFITLQNEQEISQLKKETERTQQKMKEMESVMKEQEQYIATQYKEAIDLEQELRLTREQMQNSHKELVEARHQQVQAQREIERLSSELEEIKQLSKEKEAHGKYLAEELGASQVRETQLEARMQAEIKKLSTEVESLKEAYHLEMISHQENHAKWKISVDSQKTSVQQLNEQLEKAKLELEEAQDTVSSLHQQVQDRNEVIEATNEALLIKESELTRLQAKISGHERAEDIKFLPAPFTSPVEITPDIQDSKLAKHSHTAFFKCRKLRRSISASDLSFRTHSDEDLSEELLQDLKKMQLEQPSTLEENQRDLPYTQSDSFKPLTYDLNDDNSENNDFSTLSGMLRYINKEVRLLKKSSMQTGAGSTQGENL", "length": 1456, "header": "tr|E1BN16-1|E1BN16_BOVIN Isoform 1 of Coiled-coil domain containing 18 OS=Bos taurus OX=9913 GN=CCDC18 PE=4 SV=3 CANONICAL=E1BN16-1" }, "locus": { "chromosome": "3", "start_pos": 50287742, "end_pos": 50177594, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026887.7", "url": "https://www.ensembl.org/id/ENSBTAT00000026887.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026887.6", "url": "https://www.ensembl.org/id/ENSBTAP00000026887.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:540863", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540863", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A9T7-1", "protein_name": "Coiled-coil domain containing 18", "gene_name": "Ccdc18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESSSSDYYTKDDNEEESLLANVASLRHELKITEWSLHNLGEELSSVSPSDYSDYVCNPSRSERLILEELTQPSHLGCLIYPPYKKVCKTSDRSDYQQKPGDKVPFSSVTMDQEVKNLREKLHKLRQQNAYLVTQNHSLMTKIESVHFELTHSKTKIAMLESTQEQAANIPILEEQIINLEAEVSAQDKVLREAEDKLEQSQKMVIEKEHSLQEAKEECIKLKVDLLEQSKQGKRAERQRNEALYNAEELSKAFQLYKEKVAEKLEKVQVEEEILERNLCNCEKENKRLQEKCNLYKSELEILKEKFRELKEDHYSGKEKLRIMAMKNSEVMSQLTESRQCILKLESELEDKDEILREKFSLINENRELKVRVATQNERLELCQQDIDNSRVELRSLEKLISQMPLKREIVGFKSSLSKHQMNSVSNKDKCIGCCEANKLVISELRIKLAIKEAEIQKLHANLTVNQLSHSIVAYDSRECSRVNTLETEPVKLAESIKDQGQQTVNKQYEREKQRLATGIEELRAKLVQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNASKLENEMTKKCSQLLILEKQLEEKINEYSSIAAKNAELEQELMEKNEKIRSLESNINTEHEKICFAFEKAKKIHLEQHKEMEKQIEQLETQLEKRDQQFKEQEKTMSILQQDILCKQHHLESLDRLLTESKMEMEKENMKKDEALKALQIHVSEETIKVRQLDSALEICKEELALHLNQLEGNKEKFERQLKKKSEEVYCLQKELKIKTHNLEETSEQNAILQHTLQQQQQMLQQETLRSGELEDIQSKLEKQVSKQEQELQKQRESSTEKLRKMEEKYEAAMHDVDLKRQKIVELTGTARQAKLEIDQYKEELSKLEKEITHLKRDGENKSIHLSQLDMILDQTKTELEKKTNSVKELERLQHHTETELTETTQKREALENELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMNQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQAESLNEKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEEYIATQYKEVIDLGQELRLTQEQMQSTHSELVETRRQEVQAQREIERLTGELEDVKQLSREKEAHGNRLAEELGASQVREAHLEARMQAEIKKLSSEVESLKEAYHMEMISHQENHTKWKISADSQKTSVQQLNEQLEKAKQELEEAQDTVSNLHQQVQDRNEVIEAANEALLIKESELTRLQAKISGHEKTGEAKFLTAPFTALTEIVPHVQDPKSAKHPQISLLKCRKLRRSISASDLSFKSHDNDDLSEELLQDLKKMQLEHPSALESDHKDLPVTHSESYKPLPYSLEDDGSESNDFSTLSGMLRYINREVRLLKKPPLQAATGLSQGGKL", "length": 1450 }, "evidence": [ { "id": "E1BN16", "url": "https://omabrowser.org/oma/group/E1BN16/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5T9S5-1", "protein_name": "Coiled-coil domain-containing protein 18", "gene_name": "CCDC18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESSSSDYYNKDNEEESLLANVASLRHELKITEWSLQSLGEELSSVSPSENSDYAPNPSRSEKLILDVQPSHPGLLNYSPYENVCKISGSSTDFQKKPRDKMFSSSAPVDQEIKSLREKLNKLRQQNACLVTQNHSLMTKFESIHFELTQSRAKVSMLESAQQQAASVPILEEQIINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNEALYNAEELSKAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENKDEILRDKFSLMNENRELKVRVAAQNERLDLCQQEIESSRVELRSLEKIISQLPLKRELFGFKSYLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQESSKLSSLETEPVKLGGHQVESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAEVESLKEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEALLTKESELTRLQAKISGHEKAEDIKFLPAPFTSPTEIMPDVQDPKFAKCFHTSFSKCTKLRRSISASDLTFKIHGDEDLSEELLQDLKKMQLEQPSTLEESHKNLTYTQPDSFKPLTYNLEADSSENNDFNTLSGMLRYINKEVRLLKKSSMQTGAGLNQGENV", "length": 1454 }, "evidence": [ { "id": "E1BN16", "url": "https://omabrowser.org/oma/group/E1BN16/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q640L5-1", "protein_name": "Coiled-coil domain-containing protein 18", "gene_name": "Ccdc18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEFISSDYCTKDNDNEEESLLANVASLRHELKITEWSLHNLGEELSSVSPSENSEYVCSPSRSERLILEELTQPSHLGRLIYPPYKKVCKTSDSTDYQKKSRDQVSFSSVSMDQEVKNLREKLHKLRQQNACLVTQNHSLMTKIESVHFELTQSKAKIAMLESAQEQAANIPILEEQIINLEAEVSAQDKVLREAEDKLEQSQKMVIEKEHSLQEAKEECIKLKVDLLEQSKQGKRAERQRNEALYNAEELSKAFQLYKEKVAEKLEKVQDEEEILERNLSNCEKENKRLQEKCNLYKSELEILKEKFRELKEEHYSGKEKLMIMAMKNSEVMSQLTESRQCILKLERELEDKDEIVREKFSLLNENRELKVRVATQNERLELCQQDIDNSRVELKSLEKLITQIPLKREIVGFRSSLCKHQRSSVSDKEDKCIGCCEANKLMISELRIKLAIREAEIQKLHANLTVNQLSQNVANDSQECGKVNTLETEPVKLGGSQVESIKDGDQQTVNKQYEREKQRLATGIEELRAKLTQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNASKLENEMTKKCSQLLILEKQLEEKIIAYSSIAAKNAELEQELMEKNEKIRSLESNINTEHEKICFAFEKAKKIHLEQHKEMEKQIEQLETQLEKRDQQFKEQEKTMSILQQDILCKQHHLESLDRLLTESKVEMEKENMKKDEALKALQIHVSEETIKVRQLDSALEICKEELALHLNQLERNKEKFERQLKKKSEEVYCLQKELKIKTHNLEETSEQNAILQHTLQQQQQMLQQETMRNGELEDTQSKLEKQVSKQEQELQKQRESSTEKLRKMEEKYETAIREVDLKRQKIIELTGTARQAKLEMDQYKEELSKMEKEIIHLKRDGENKSMQLSQLDMVLDQTKTELEKTTNSVKELERLQHHTETELTETMQKREALENELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELIEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQVESLNEKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVIKEQEDYIATQYKEVIDLGQELRLTQEQMQNTHSELVEARRQEVQAQREIERLAGELEDIKQLSKEKEAHGNRLAEELGASQVREAHLEARMQAEIKKLSSEVDSLKEAYQIEMISHQENHAKWKLSAESQKTSVQQLNEQLEKAKQELEEAQDTVSNLHQQVQDRNEVIEAANEALLIKESELTRLQAKISGHEKTEDTKYLPAPFTTLTEIIPDSQHPNFAKHSQISLFKCRKLRRSISASDLSFKSHGNDDLSEELLQDLKKMQFEQTSAIESGHKDLPLTHSESFKPLPYNLEDDSSESNDFSTLSGMLRYINKEVRLLKKSSLQTATGLSQGGKL", "length": 1455 }, "evidence": [ { "id": "E1BN16", "url": "https://omabrowser.org/oma/group/E1BN16/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BN16", "url": "https://www.uniprot.org/uniprotkb/E1BN16" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 464, "end_pos": 466, "annotation": "n_glycosylation_sequon" }, { "start_pos": 473, "end_pos": 475, "annotation": "n_glycosylation_sequon" }, { "start_pos": 567, "end_pos": 569, "annotation": "n_glycosylation_sequon" }, { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" }, { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" }, { "start_pos": 777, "end_pos": 779, "annotation": "n_glycosylation_sequon" }, { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 137, "end_pos": 139 }, { "start_pos": 464, "end_pos": 466 }, { "start_pos": 473, "end_pos": 475 }, { "start_pos": 567, "end_pos": 569 }, { "start_pos": 57, "end_pos": 59 }, { "start_pos": 68, "end_pos": 70 }, { "start_pos": 777, "end_pos": 779 }, { "start_pos": 79, "end_pos": 81 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BN31-1", "uniprot_ac": "E1BN31", "uniprot_id": "E1BN31_BOVIN", "mass": { "chemical_mass": 58831.0, "monoisotopic_mass": 58831.0 }, "refseq": { "ac": "XP_002685553", "name": "hyccin 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002685553" }, "gene_names": [ { "name": "HYCC2", "type": "recommended", "evidence": [ { "id": "E1BN31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN31" } ] }, { "name": "HYCC2", "type": "synonym", "evidence": [ { "id": "XP_002685553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002685553" } ] } ], "protein_names": [ { "name": "Hyccin PI4KA lipid kinase complex subunit 2", "type": "synonym", "evidence": [ { "id": "E1BN31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN31/entry#names_and_taxonomy" } ] }, { "name": "hyccin 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_002685553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002685553" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BN31", "url": "https://www.uniprot.org/uniprotkb/E1BN31" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HYCC2", "url": "https://www.uniprot.org/uniprotkb/E1BN31", "locus": { "chromosome": "2", "start_pos": 89604072, "end_pos": 89662329, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021201", "url": "https://www.ensembl.org/id/ENSBTAG00000021201" } ] } } ], "crossref": [ { "id": "E1BN31", "url": "https://alphafold.ebi.ac.uk/entry/E1BN31", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021201", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021201", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "533324", "url": "https://www.ncbi.nlm.nih.gov/gene/533324", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018619", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018619", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:533324", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:533324", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SIYHEXF", "url": "https://omabrowser.org/oma/group/SIYHEXF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M966", "url": "https://www.orthodb.org/?gene=A0A3Q1M966", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BN31", "url": "https://www.orthodb.org/?gene=E1BN31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31220", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31220", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31220:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31220:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09790", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09790", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002685553", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002685553", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M966", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M966", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M966-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M966-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN31", "url": "https://www.uniprot.org/uniprotkb/E1BN31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN31-1", "url": "https://www.uniprot.org/uniprotkb/E1BN31-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGSERGVVEEWLSEFKALPDTQITNYAATLHRKKTLVPALYKVIQDSNNELLEPVCHQLFELYRSSEVRLKRFTLQFLPELMWVYLRLTVSRDRQSNGCIEALLLGIYNLEIADKDGNNKVLSFTIPSLSKPSIYHEPSTIGSMALTEGALCQHDLIRVVYSDLHPQRETFTAQNRFEVLSFLMLCYNSAIVYMPASSYQSLCRMGSRVCVSGFPRQHEKQWKELCGRIVLDPEFMVQLLTGVYYAMYNGQWDLGQEVLDDIIYRAQLELFSQPLLVANAMKNSLPFDAPDSSQEGQKVLKVEVTPTVPRISRSAITTASIRRHRWRREGAEGINGGEESVNLNDADEGFSSGASLSSQPIGIKPSSSSQRGSLRKVATGRSAKDKETTSAIKSNESPRDSVVRRQYVQQPTDLSVDSIELTPMKKHLSLPAGQVVPKTNSINLIRTASASSSKSFDYVNGSQASTSIGVGTEGITNLAANNANRYSTVSLQEDRLGQATEGKELLSPGAPLTKQSRSPSFNMQLISQV", "length": 530, "header": "tr|E1BN31-1|E1BN31_BOVIN Isoform 1 of Hyccin PI4KA lipid kinase complex subunit 2 OS=Bos taurus OX=9913 GN=HYCC2 PE=3 SV=2 CANONICAL=E1BN31-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M966-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M966/entry", "sequence": { "sequence": "MLGSERGVVEEWLSEFKALPDTQITNYAATLHRKKTLVPALYKVIQDSNNELLEPVCHQLFELYRSSEVRLKRFTLQFLPELMWVYLRLTVSRDRQSNGCIEALLLGIYNLEIADKDGNNKVLSFTIPSLSKPSIYHEPSTIGSMALTEGALCQHDLIRVVYSDLHPQRETFTAQNRFEVLSFLMLCYNSAIVYMPASSYQSLCRMGSRVCVSGFPRQHEKQWKELCGRIVLDPEFMVQLLTGVYYAMYNGQWDLGQEVLDDIIYRAQLELFSQPLLVANAMKNSLPFDAPDSSQEGQKVLKVEVTPTVPRISRSAITTASIRRHRWRREDGFDFSNEADSSIPGSPIQHGSTDLGIKRVQEGEVLVHRTPEHGSPEPNSAAATTEGAEGINGGEESVNLNDADEGFSSGASLSSQPIGIKPSSSSQRGSLRKVATGRSAKDKETTSAIKSNESPRDSVVRRQYVQQPTDLSVDSIELTPMKKHLSLPAGQVVPKTNSINLIRTASASSSKSFDYVNGSQASTSIGVGTEGITNLAANNANRYSTVSLQEDRLGQATEGKELLSPGAPLTKQSRSPSFNMQLISQV", "length": 586, "header": "tr|A0A3Q1M966-1|A0A3Q1M966_BOVIN Computationally mapped isoform of Hyccin PI4KA lipid kinase complex subunit 2 OS=Bos taurus OX=9913 GN=HYCC2 PE=3 SV=1 CANONICAL=E1BN31-1" }, "locus": { "chromosome": "2", "start_pos": 89638339, "end_pos": 89605076, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081087.2", "url": "https://www.ensembl.org/id/ENSBTAT00000081087.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067084.1", "url": "https://www.ensembl.org/id/ENSBTAP00000067084.1" } ] } }, { "isoform_ac": "E1BN31-1", "url": "https://www.uniprot.org/uniprotkb/E1BN31/entry", "sequence": { "sequence": "MLGSERGVVEEWLSEFKALPDTQITNYAATLHRKKTLVPALYKVIQDSNNELLEPVCHQLFELYRSSEVRLKRFTLQFLPELMWVYLRLTVSRDRQSNGCIEALLLGIYNLEIADKDGNNKVLSFTIPSLSKPSIYHEPSTIGSMALTEGALCQHDLIRVVYSDLHPQRETFTAQNRFEVLSFLMLCYNSAIVYMPASSYQSLCRMGSRVCVSGFPRQHEKQWKELCGRIVLDPEFMVQLLTGVYYAMYNGQWDLGQEVLDDIIYRAQLELFSQPLLVANAMKNSLPFDAPDSSQEGQKVLKVEVTPTVPRISRSAITTASIRRHRWRREGAEGINGGEESVNLNDADEGFSSGASLSSQPIGIKPSSSSQRGSLRKVATGRSAKDKETTSAIKSNESPRDSVVRRQYVQQPTDLSVDSIELTPMKKHLSLPAGQVVPKTNSINLIRTASASSSKSFDYVNGSQASTSIGVGTEGITNLAANNANRYSTVSLQEDRLGQATEGKELLSPGAPLTKQSRSPSFNMQLISQV", "length": 530, "header": "tr|E1BN31-1|E1BN31_BOVIN Isoform 1 of Hyccin PI4KA lipid kinase complex subunit 2 OS=Bos taurus OX=9913 GN=HYCC2 PE=3 SV=2 CANONICAL=E1BN31-1" }, "locus": { "chromosome": "2", "start_pos": 89638339, "end_pos": 89605076, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000044582.4", "url": "https://www.ensembl.org/id/ENSBTAT00000044582.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000042066.2", "url": "https://www.ensembl.org/id/ENSBTAP00000042066.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:533324", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:533324", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A4F1-1", "protein_name": "Hyccin PI4KA lipid kinase complex subunit 2", "gene_name": "HYCC2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLGSERAVVEEWLSEFKALPDTQITNYAATLHRKKTLVPALYKVIQDSNNELLEPVCHQLFELYRSSEVRLKRFTLQFLPELMWVYLRLTVSRDRQSNGCIEALLLGIYNLEIADKDGNNKVLSFTIPSLSKPSIYHEPSTIGSMALTEGALCQHDLIRVVYSDLHPQRETFTAQNRFEVLSFLMLCYNSAIVYMPASSYQSLCRMGSRVCVSGFPRQHEKHWKELCGRIVLDPEFMVQLLTGVYYAMYNGQWDLGQEVLDDIIYRAQLELFSQPLLVANAMKNSLPFDAPDSSQEGQKVLKVEVTPTVPRISRTAITTASIRRHRWRREGAEGINGGEELVNLNDADEGFSSGASLSSQPVGTKPSSSSQRGSLRKVATGRSAKDKETTSAVKSTESPRDSVVRRQYVQQPTDLSVDSIELTPMKKHLSLPAGQVVPKTNSLSLIRTASASSSKSFDYVNGSQASTSIGVGTEGVTNLAANNANRYSTISLQEDRLGQAGEGKELLSPGAPLTKQSRSPSFNMQLISQV", "length": 530 }, "evidence": [ { "id": "E1BN31", "url": "https://omabrowser.org/oma/group/E1BN31/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5ZT89-1", "protein_name": "Hyccin PI4KA lipid kinase complex subunit 2", "gene_name": "Hycc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLGSERAVVEEWLSEFKALPDTQITSYAATLHRKKALVPALYKVIQDSNNELLEPVCHQLFELYRSSEVRLKRFTLQFLPELIWVYLRLTVSRDRQSNGCIEALLLGIYNLEIADKDGNNKVLSFTIPSLSKPSIYHEPSTIGSMALTEGALCQHDLIRVVYSDLHPQRETFTAQNRFEVLSFLMLCYNSAIVYMPASSYQSLCRMGSRVCVSGFPRQHEKQWKELCGRIVLDPEFMVQLLTGVYYAMYNGQWDLGQEVLDDIIYRAQLELFSQPLLVANAMKNSLPFDAPDSSQEGQKVLKVEVTPTVPRISRTAITTASIRRHRWRREGAEGLNGGEESLNMNDADEGFSSGASLSSQPHGTKPSSSSQRGSLRKVATGRSAKDKETASAIKSNESPRDSVVGKQFLQQADLSIDSVELTPMKKHLSLPAGQVVPKTNSLSLIRTASASSSKSFDYVNGGQASTSIGVGTEGVTNLAATNTNRYSTISLQEDRLGHAGEGKELLSPGAPLTKQSRSPSFNMQLISQV", "length": 529 }, "evidence": [ { "id": "E1BN31", "url": "https://omabrowser.org/oma/group/E1BN31/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V1A2H6-1", "protein_name": "Hyccin PI4KA lipid kinase complex subunit 2", "gene_name": "FAM126B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLGSERGVVEEWLSEFKALPETQISSYAATLHRKKPLVPALYKVIQDPNNELLEPVCHQLFELYRSSEVRLKRFTLQFLPELIWVYLRLTASRDRQSNGCIEALLLGIYNLEIADKDGNNKVLSFTIPSLSKPSIYHEPSTIGSMALTEGALCQHDLIRVVYSDLHPQRETFTAQNRFEVLSFLMLCYNSAIVYMPASSYQSLCRMGSRLCVSGFPRQHEKRWKEHCGRVVLDPDFMVQLLTGVYYAIYNGQWDLGQEVLEDIIYRAQLELYSQPLLVANAMKNSLPFDAPDASQEGQKVLKVEVTPTVPRISRTAITTASIRRHRWRREDTEGVNGREESVNLNDADEGFSSGASLSSQPVGTKPQSSISQKGSLRKTASGRSAKDKETSSAAKSNDSPRDSVARKQYMHQSTDLGADIIEMTPTKKHLSLPAGQVVPKANSLSLIRTASASSSKSFDYVNGSQAGSSVGVGTEGVTNLAAGNTNRFSTISLQEDRLGHTGEGKDLLPPGTPLTKQSRSPSFNMQLISQV", "length": 531 }, "evidence": [ { "id": "E1BN31", "url": "https://omabrowser.org/oma/group/E1BN31/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7K456-1", "protein_name": "Protein FAM126B isoform X1", "gene_name": "Fam126b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLGSERAVVEEWLSEFKALPDTQITNYAATLHRKKALVPALYKVIQDSNNELLEPVCHQLFELYRSSEVRLKRFTLQFLPELMWVYLRLTVSRDRQSNGCIEALLLGIYNLEIADKDGNNKVLSFTIPSLSKPSIYHEPSTIGSMALTEGALCQHDLIRVVYSDLHPQRETFTAQNRFEVLSFLMLCYNSAIVYMPASSYQSLCRMGSRVCVSGFPRQHEKQWKEICGRIVLDPEFMVQLLTGVYYAMYNGQWDLGQEVLDDIIYRAQLELFSQPLLVANAMKNSLPFDAPDSSQEGQKVLKVEVTPTVPRISRTAITTASIRRHRWRREDGFDFSNEADSSIPGSPIQPGSTDLGIKRVQEGEVRRTPEHGSPEPNSAAATTEGRTEMRRQKSVRQLLEKDPGSLSPSRAPFHSSAEGLNGGEESLNMNDADEGFSSGASLSSQPHGTKPSSSSQRGSLRKVATGRSAKDKETASAIKSSESPRDSVVRKQFVQPADLSIDSVELTPMKKHLSLPAGQVVPKTNSLSLIRTASASSSKSFDYVNGSQASTSIGVGTEGVTNLAATNANRYSTISLQEDRLGHAGEGKELLSPGAPLTKQSRSPSFNMQLISQV", "length": 614 }, "evidence": [ { "id": "E1BN31", "url": "https://omabrowser.org/oma/group/E1BN31/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8C729-1", "protein_name": "Hyccin 2", "gene_name": "Hycc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLGSERAVVEEWLSEFKALPDTQITSYAATLHRKKALVPALYKVIQDSNNELLEPVCHQLFELYRSSEVRLKRFTLQFLPELIWVYLRLTVSRDRQSNGCIEALLLGIYNLEIADKDGNNKVLSFTIPSLSKPSIYHEPSTIGSMALTEGALCQHDLIRVVYSDLHPQRETFTAQNRFEVLSFLMLCYNSAIVYMPASSYQSLCRMGSRVCVSGFPRQHEKQWKELCGRIVLDPEFMVQLLTGVYYAMYNGQWDLGQEVLDDIIYRAQLELFSQPLLVANAMKNSLPFDAPDSSQEGQKVLKVEVTPTVPRISRTAITTASIRRHRWRREGAEGLNGGEESLNMNDADEGFSSGASLSSQPHGTKPPSSSQRGSLRKVATGRSAKDKETALAIKSNESPRDSVVGKQFVQQQADLSIDSVELTPMKKHLSLPAGQVVPKTNSLSLIRTASASSSKSFDYVNGGQASTSIGVGTEGVTNLAATNANRYSTISLQEDRLGHAGEGKELLSPGAPLTKQSRSPSFNMQLISQV", "length": 530 }, "evidence": [ { "id": "E1BN31", "url": "https://omabrowser.org/oma/group/E1BN31/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IXS8-1", "protein_name": "Hyccin 2", "gene_name": "HYCC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLGTDRCVVEEWLSEFKALPDTQITSYAATLHRKKTLVPALYKVIQDSNNELLEPVCHQLFELYRSSEVRLKRFTLQFLPELMWVYLRLTVSRDRQSNGCIEALLLGIYNLEIADKDGNNKVLSFTIPSLSKPSIYHEPSTIGSMALTEGALCQHDLIRVVYSDLHPQRETFTAQNRFEVLSFLMLCYNSAIVYMPASSYQSLCRMGSRVCVSGFPRQHEKHWKELCGRIVLDPEFMVQLLTGVYYAMYNGQWDLGQEVLDDIIYRAQLELFSQPLLVANAMKNSLPFDAPDSTQEGQKVLKVEVTPTVPRISRTAITTASIRRHRWRREGAEGVNGGEESVNLNDADEGFSSGASLSSQPIGTKPSSSSQRGSLRKVATGRSAKDKETASAIKSSESPRDSVVRKQYVQQPTDLSVDSVELTPMKKHLSLPAGQVVPKINSLSLIRTASASSSKSFDYVNGSQASTSIGVGTEGGTNLAANNANRYSTVSLQEDRLGQAGEGKELLSPGAPLTKQSRSPSFNMQLISQV", "length": 530 }, "evidence": [ { "id": "E1BN31", "url": "https://omabrowser.org/oma/group/E1BN31/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BN31", "url": "https://www.uniprot.org/uniprotkb/E1BN31" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BN31", "url": "https://www.uniprot.org/uniprotkb/E1BN31" } ], "pmid": "" }, { "name": "cell junction", "id": "GO:0030054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030054", "evidence": [ { "database": "UniProtKB", "id": "E1BN31", "url": "https://www.uniprot.org/uniprotkb/E1BN31" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "E1BN31", "url": "https://www.uniprot.org/uniprotkb/E1BN31" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate biosynthetic process", "id": "GO:0046854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046854", "evidence": [ { "database": "UniProtKB", "id": "E1BN31", "url": "https://www.uniprot.org/uniprotkb/E1BN31" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" }, { "start_pos": 461, "end_pos": 463, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BN31-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 530, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BN31-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BN31" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 396, "end_pos": 398 }, { "start_pos": 461, "end_pos": 463 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BN32-1", "uniprot_ac": "E1BN32", "uniprot_id": "E1BN32_BOVIN", "mass": { "chemical_mass": 235584.0, "monoisotopic_mass": 235584.0 }, "refseq": {}, "gene_names": [ { "name": "RP1L1", "type": "recommended", "evidence": [ { "id": "E1BN32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN32" } ] } ], "protein_names": [ { "name": "RP1 like 1", "type": "synonym", "evidence": [ { "id": "E1BN32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN32/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BN32", "url": "https://www.uniprot.org/uniprotkb/E1BN32" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RP1L1", "url": "https://www.uniprot.org/uniprotkb/E1BN32", "locus": { "chromosome": "8", "start_pos": 8669305, "end_pos": 8659609, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020155", "url": "https://www.ensembl.org/id/ENSBTAG00000020155" } ] } } ], "crossref": [ { "id": "ENSBTAG00000020155", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020155", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR003533", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003533", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036572", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036572", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BN32", "url": "https://www.orthodb.org/?gene=E1BN32", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23005", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23005", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23005:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23005:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03607", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03607", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BN32", "url": "https://www.uniprot.org/uniprotkb/E1BN32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN32-1", "url": "https://www.uniprot.org/uniprotkb/E1BN32-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"PF16546", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16546", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179720", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179720", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BN39", "url": "https://www.uniprot.org/uniprotkb/E1BN39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN39-1", "url": "https://www.uniprot.org/uniprotkb/E1BN39-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSIKHLVYAVIRFLREQSQMDAYTSDEQESLEVAIQCLETVFKISAEDTHLAVSQPLTEMFTNSFCKNDILPLSNSVPEDMGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDSNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFQEAVTSYQKALDLDPENDSYKSNLKIAEQKLREVSSPTGTGLSFDMASLINNPAFISMAASLMQNPQVQQLMSGMMTNAIGGPAAGVGGLTDLSSLIQAGQQFAQQIQQQNPELIEQLRNHIRSRSFSSSAEEHS", "length": 304, "header": "tr|E1BN39-1|E1BN39_BOVIN Isoform 1 of Small glutamine-rich tetratricopeptide repeat-containing protein beta OS=Bos taurus OX=9913 GN=SGTB PE=3 SV=1 CANONICAL=E1BN39-1" }, "isoforms": [ { "isoform_ac": "E1BN39-1", "url": "https://www.uniprot.org/uniprotkb/E1BN39/entry", "sequence": { "sequence": "MSSIKHLVYAVIRFLREQSQMDAYTSDEQESLEVAIQCLETVFKISAEDTHLAVSQPLTEMFTNSFCKNDILPLSNSVPEDMGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDSNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFQEAVTSYQKALDLDPENDSYKSNLKIAEQKLREVSSPTGTGLSFDMASLINNPAFISMAASLMQNPQVQQLMSGMMTNAIGGPAAGVGGLTDLSSLIQAGQQFAQQIQQQNPELIEQLRNHIRSRSFSSSAEEHS", "length": 304, "header": "tr|E1BN39-1|E1BN39_BOVIN Isoform 1 of Small glutamine-rich tetratricopeptide repeat-containing protein beta OS=Bos taurus OX=9913 GN=SGTB PE=3 SV=1 CANONICAL=E1BN39-1" }, "locus": { "chromosome": "20", "start_pos": 13899289, "end_pos": 13855107, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022481.7", "url": "https://www.ensembl.org/id/ENSBTAT00000022481.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022481.4", "url": "https://www.ensembl.org/id/ENSBTAP00000022481.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:540864", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540864", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061ILR7-1", "protein_name": "Small glutamine-rich tetratricopeptide repeat-containing protein beta", "gene_name": "Sgtb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSVKPLVYAVIRFLREQSQMDAYTSDEQESLEVAIQCLETVFKISSEDTHLAVSQPLTEMFTNTVCKNDILPLSNSVPEDVGKADQLKDEGNNHMKEENYTAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLREVASPTGTGLSFDMASLINNPAFITMAASLMQNPQVQQLMSGMMTNAIGGPAAGVGGLTDLSSLIQAGQQFAQQIQQQNPELIEQLRNHIRSRSFSSSTEEHS", "length": 304 }, "evidence": [ { "id": "E1BN39", "url": "https://omabrowser.org/oma/group/E1BN39/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1R7L2-1", "protein_name": "Small glutamine-rich tetratricopeptide repeat-containing protein beta", "gene_name": "sgtb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTVERALRALSPDKMAVEKRLAYSMVQFLRDQTHCGSLNSDEQESLEVAIQCLETTFKISSSDCHLAAPQPLREIFLNSLLKNDIVTLPKTFPSPEDIERAEQLKNEGNNHMKEENYSSAVDCYTKAIELDQRNAVYYCNRAAAHSKLENYTEAMGDCERAIAIDPSYSKAYGRMGLALTSMSKYPEAISYFNKALVLDPENDTYKSNLKIVEQKQKEASSPTATGLGFDMASLINNPAFISMAASVMQNQQVQQLMSGMMSNAVGGPAAGVGGLSDISSLIEAGQQFAQQIQQQNPELIEQLRNHIRSRSFSGSAEEHS", "length": 320 }, "evidence": [ { "id": "E1BN39", "url": "https://omabrowser.org/oma/group/E1BN39/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q12118-1", "protein_name": "Small glutamine-rich tetratricopeptide repeat-containing protein 2", "gene_name": "SGT2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSASKEEIAALIVNYFSSIVEKKEISEDGADSLNVAMDCISEAFGFEREAVSGILGKSEFKGQHLADILNSASRVPESNKKDDAENVEINIPEDDAETKAKAEDLKMQGNKAMANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEEALEAYKKVLDIEGDNATEAMKRDYESAKKKVEQSLNLEKTVPEQSRDADVDASQGASAGGLPDLGSLLGGGLGGLMNNPQLMQAAQKMMSNPGAMQNIQKMMQDPSIRQMAEGFASGGGTPNLSDLMNNPALRNMAGNLFGGAGAQSTDETPDNENKQ", "length": 346 }, "evidence": [ { "id": "E1BN39", "url": "https://omabrowser.org/oma/group/E1BN39/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q80W98-1", "protein_name": "Small glutamine-rich tetratricopeptide repeat-containing protein beta", "gene_name": "Sgtb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSVKPLVYAVIRFLREQSQMDAYTSDEQESLEVAIQCLETVFKISPEDTHLAVSQPLTEMFTNSVCKNDIRPLSNSVPEDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLREVSSPTGTGLTFDMASLINNPAFITMAASLMQNPQVQQLMSGMMTNAIGGPAAGVGGLTDLSSLIQAGQQFAQQIQQQNPELIEQLRNHIRSRSFSSSTEEHS", "length": 304 }, "evidence": [ { "id": "E1BN39", "url": "https://omabrowser.org/oma/group/E1BN39/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VD33-1", "protein_name": "Small glutamine-rich tetratricopeptide repeat-containing protein beta", "gene_name": "Sgtb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSVKPLVYAVIRFLREQSQMDAYTSDEQESLEVAIQCLETVFKISPEDTHLAVSQPLTEMFTNSVCKNDIRPLSNSVPEDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLREVSSPTGTGLSFDMASLINNPAFITMAASLMQNPQVQQLMSGMMTNAIGGPAAGVGGLTDLSSLIQAGQQFAQQIQQQNPELIEQLRNHIRSRSFSSSADEHS", "length": 304 }, "evidence": [ { "id": "E1BN39", "url": "https://omabrowser.org/oma/group/E1BN39/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96EQ0-1", "protein_name": "Small glutamine-rich tetratricopeptide repeat-containing protein beta", "gene_name": "SGTB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSIKHLVYAVIRFLREQSQMDTYTSDEQESLEVAIQCLETVFKISPEDTHLAVSQPLTEMFTSSFCKNDVLPLSNSVPEDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLREVSSPTGTGLSFDMASLINNPAFISMAASLMQNPQVQQLMSGMMTNAIGGPAAGVGGLTDLSSLIQAGQQFAQQIQQQNPELIEQLRNHIRSRSFSSSAEEHS", "length": 304 }, "evidence": [ { "id": "E1BN39", "url": "https://omabrowser.org/oma/group/E1BN39/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VJD4-1", "protein_name": "Small glutamine-rich tetratricopeptide containing protein, isoform A", "gene_name": "Sgt", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPDAVQQSFVRSFIDYLKKQGDVMSPDQTESIEVAIQCLQAAFDLGDDVEAAPAAAGEEQATTQSSSTASAPDDDAVASGSAGIGAAAAAVPNNIDMFELFQSLYTERNPESLALAESIKNEGNRLMKENKYNEALLQYNRAIAFDPKNPIFYCNRAAAHIRLGENERAVTDCKSALVYNNNYSKAYCRLGVAYSNMGNFEKAEQAYAKAIELEPDNEVYKSNLEAARNARNQPPQTGRLREDLINMLSQPMVRNLFNNAEIDVEQLLSMLQNPMIMNTIRQQFGGGNAPTLPNDMVQMIYNMTSQLTGFPNSNANPGNEQQPGNQPPPST", "length": 331 }, "evidence": [ { "id": "E1BN39", "url": "https://omabrowser.org/oma/group/E1BN39/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "post-translational protein targeting to endoplasmic reticulum membrane", "id": "GO:0006620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006620", "evidence": [ { "database": "UniProtKB", "id": "E1BN39", "url": "https://www.uniprot.org/uniprotkb/E1BN39" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "E1BN39", "url": "https://www.uniprot.org/uniprotkb/E1BN39" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1BN39", "url": "https://www.uniprot.org/uniprotkb/E1BN39" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BN39", "url": "https://www.uniprot.org/uniprotkb/E1BN39" } ], "pmid": "" }, { "name": "TRC complex", "id": "GO:0072380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072380", "evidence": [ { "database": "UniProtKB", "id": "E1BN39", "url": "https://www.uniprot.org/uniprotkb/E1BN39" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BN39-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 304, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BN39-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BN39" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BN39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN39" }, { "id": "PF16546", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16546" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SGTA homodimerisation", "eco_id": "ECO_0000259", "start_pos": 5, "end_pos": 63, "start_aa": "Lys", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 186, "end_pos": 188 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BN45-1", "uniprot_ac": "E1BN45", "uniprot_id": "E1BN45_BOVIN", "mass": { "chemical_mass": 62068.0, "monoisotopic_mass": 62068.0 }, "refseq": { "ac": "XP_015329747", "name": "cerebral cavernous malformations 2 protein-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015329747" }, "gene_names": [ { "name": "CCM2L", "type": "recommended", "evidence": [ { "id": "E1BN45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN45" } ] }, { "name": "CCM2L", "type": "synonym", "evidence": [ { "id": "XP_015329747", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015329747" } ] } ], "protein_names": [ { "name": "CCM2 like scaffold protein", "type": "synonym", "evidence": [ { "id": "E1BN45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN45/entry#names_and_taxonomy" } ] }, { "name": "cerebral cavernous malformations 2 protein-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015329747", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015329747" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BN45", "url": "https://www.uniprot.org/uniprotkb/E1BN45" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CCM2L", "url": "https://www.uniprot.org/uniprotkb/E1BN45", "locus": { "chromosome": "13", "start_pos": 61545663, "end_pos": 61525299, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000031453", "url": "https://www.ensembl.org/id/ENSBTAG00000031453" } ] } } ], "crossref": [ { "id": "E1BN45", "url": "https://alphafold.ebi.ac.uk/entry/E1BN45", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000031453", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000031453", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13166", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13166", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13516", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13516", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "525479", "url": "https://www.ncbi.nlm.nih.gov/gene/525479", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032375", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032375", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:525479", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:525479", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ETFEAYC", "url": "https://omabrowser.org/oma/group/ETFEAYC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BN45", "url": "https://www.orthodb.org/?gene=E1BN45", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21642", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21642", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21642:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21642:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16545", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16545", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015329747", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015329747", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BN45", "url": "https://www.uniprot.org/uniprotkb/E1BN45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN45-1", "url": "https://www.uniprot.org/uniprotkb/E1BN45-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEYEVKKGKKGFVSPIRRLVFPKAARRAACRSSVSRRPLHSMPLYPPDYLIDPQILLCDYLEKEVKFLGHLTWVTSSLNPSSRDELLQLLDTARQLKELPLKTTAEQDSILSLSARCLLLTWRDNEELILRIPTHEIAAASYLQDDALHLLVLKTGLGVDPVPAGVDASPGGAGRDPGPPGVSPEKRRVGTTERRHTICSLDWRMAWGGGAGAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHAGGGGGTGKPGGSWERRQAGGGGGSWERRHPGPNPLDPQDPSPDAYCNLVILAVANRDAAEESCALICQVFQIIYGDQSIECVDRAGYHYTSTPERPWLCSRSESCRTDGTYAYDADFSCCSSFNSSQDTFEACYSGTSTPSFHGSHCSSSDHSGLGLEQLQDYMVTLRTKLGPPEIQQFALLLREYRLGLPIQDYCAGLLKLYGDRRKFLLLGMRPFIPDQDIGYFEGFLEGVGIREGGILTDSFGRIKRSMSSTSASAVRSYDGAQRPEAQAFHRLLTDITHDIEALAPDDDESTDEEARDSPGGGDAAEDNYL", "length": 568, "header": "tr|E1BN45-1|E1BN45_BOVIN Isoform 1 of CCM2 like scaffold protein OS=Bos taurus OX=9913 GN=CCM2L PE=3 SV=3 CANONICAL=E1BN45-1" }, "isoforms": [ { "isoform_ac": "E1BN45-1", "url": "https://www.uniprot.org/uniprotkb/E1BN45/entry", "sequence": { "sequence": "MEYEVKKGKKGFVSPIRRLVFPKAARRAACRSSVSRRPLHSMPLYPPDYLIDPQILLCDYLEKEVKFLGHLTWVTSSLNPSSRDELLQLLDTARQLKELPLKTTAEQDSILSLSARCLLLTWRDNEELILRIPTHEIAAASYLQDDALHLLVLKTGLGVDPVPAGVDASPGGAGRDPGPPGVSPEKRRVGTTERRHTICSLDWRMAWGGGAGAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHAGGGGGTGKPGGSWERRQAGGGGGSWERRHPGPNPLDPQDPSPDAYCNLVILAVANRDAAEESCALICQVFQIIYGDQSIECVDRAGYHYTSTPERPWLCSRSESCRTDGTYAYDADFSCCSSFNSSQDTFEACYSGTSTPSFHGSHCSSSDHSGLGLEQLQDYMVTLRTKLGPPEIQQFALLLREYRLGLPIQDYCAGLLKLYGDRRKFLLLGMRPFIPDQDIGYFEGFLEGVGIREGGILTDSFGRIKRSMSSTSASAVRSYDGAQRPEAQAFHRLLTDITHDIEALAPDDDESTDEEARDSPGGGDAAEDNYL", "length": 568, "header": "tr|E1BN45-1|E1BN45_BOVIN Isoform 1 of CCM2 like scaffold protein OS=Bos taurus OX=9913 GN=CCM2L PE=3 SV=3 CANONICAL=E1BN45-1" }, "locus": { "chromosome": "13", "start_pos": 61544659, "end_pos": 61525479, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000044564.5", "url": "https://www.ensembl.org/id/ENSBTAT00000044564.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000042050.4", "url": "https://www.ensembl.org/id/ENSBTAP00000042050.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:525479", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:525479", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZSU2-1", "protein_name": "CCM2 like scaffold protein", "gene_name": "Ccm2l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEYEAKKGKKGFVSPIRRLVFPKAARQAAFKSNVSRRPLHSMPLYPPDYLIDPHILLCDYLEKEVKFLGHLTWVTSSLNPSSRDELLQLLDTARQLKELPLKTTPEQDSILSLSARCLLLTWRDNEELILRIPTHEIAAASYLQDDALHLLVLKTGLGVDPVPAGMDGSPGSSGRDPGPPGAAPEKRRVGTAERRHTICSLDWRMAWGGGAGAEARAAGGGGSLERQRAGARASGSWERRQTFSGSWERRHAGGGAGKPGGSWERRQASGGVGGSWERRHPGPNPLDPQNHSPDAYCNLVILAVANRDAAEESCALICQVFQIIYGDQSIECVDRAGYHYRPTPKRPWLSSCSESCRTDGTFAYDADLSCCSSFNGSQDTFEACYSGASTPSFHSSHCSSIDHSSWAFEQLQDYMVTLRSKLGPPEIQQFAMLLRDYRLGLPIQDYCAGLQKLYGDRRKFLLIGMRPFIPDQDIGYFEGFLESMGIREGGILTDSFGRIKRSMSSTSASAVRSYDGAAQRPEEQTFHQLLTDITHDIEALAPDDDDVYEDVSPSGGDQVEDNYL", "length": 564 }, "evidence": [ { "id": "E1BN45", "url": "https://omabrowser.org/oma/group/E1BN45/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S526-1", "protein_name": "CCM2 like scaffold protein", "gene_name": "CCM2L", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEYEVKKGKKGFVSPIRRLVFPKAGRRAACRSSVSRRPLHSMPLYPPDYLIDPQILLCDYLEKEVKFLGHLTWVTSSLNPSSRDELLQLLDTARQLKELPLKTTAEQDSILSLSARCLLLTWRDNEELILRIPTHEIAAASYLQDDALHLLVLKTGLGVDPVPAGVDASPGGAGRDPGPPGAAPEKRRVGTTERRHTICSLDWRMAWGGGAGAEARVGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGAGKPGGSWERRQAGGGGSWERRHPGTNPLDPQDPSPDAYCNLVILAVANRDAAEESCALICQVFQIIYGDQSIECVDRAGYHYTSTPERPWLCSRSESCRTDGTYAYDADFSCCSSFNGSQDTFEACYSGTSTPSFHGSHCSGSDHSGLGLEQLQDYMITLRSKLGPLEIQQFALLLREYRLGLPIQDYCAGLLKLYGDRRKFLLLGMRPFIPDQDIGYFEGFLEGVGIREGGILTDSFGRIKRSMSSTSASAVRSYDGAAQRPEAQAFHRLLADITHDIEALAPDDDDSTDEESRGSPGGGDAAEDNYL", "length": 568 }, "evidence": [ { "id": "E1BN45", "url": "https://omabrowser.org/oma/group/E1BN45/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8VCC6-1", "protein_name": "Cerebral cavernous malformations 2 protein-like", "gene_name": "Ccm2l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEYEAKKGKKGFVSPIRRLVFPKAARQAAFRSSVSRRPLHSMPLYPPDYLIDPHILLCDYLEKEVKFLGHLTWVTSSLNPSSRDELLQLLDTARQLKELPLKTTPEQDSILSLSARCLLLTWRDNEELILRIPTHEIAAASYLQDDALHLLVLKTGLGVDPVPAGMDGSPGGSGRDPGPPGAAPEKRRVGTAERRHTICSLDWRVAWGGGAGAEARAAGGGGSLERQRAGARASGSWERRQTFSGSWERRHAGGGAGKPGGSWERRQASGGVGGSWERRHPGPNPLDPQNHSPDAYCNLVILAVANRDAAEESCALICQVFQIIYGDQSIECVDRAGYHYRSTPKRPWLSSCTMAPRTHLKRATVAHPHRLSTAPTAAVSTTAAGPSSSYRITWSRCGVSWVLLRSSSLHCCYETIVWGCLSRTTVQVCRNSMGTDGSSFSLECGPSSQIRTSATSRASWRVWVSARAESSLTALAASSAA", "length": 481 }, "evidence": [ { "id": "E1BN45", "url": "https://omabrowser.org/oma/group/E1BN45/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NUG4-1", "protein_name": "Cerebral cavernous malformations 2 protein-like", "gene_name": "CCM2L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEYEVKKGKKGFVSPIRRLVFPKAGRRAACRSSVSRRPLHSMPLYPPDYLIDPQILLCDYLEKEVKFLGHLTWVTSSLNPSSRDELLQLLDTARQLKELPLKTTAEQDSILSLSARCLLLTWRDNEELILRIPTHEIAAASYLQDDALHLLVLKTGLGVDPVPAGVDASPGGAGRDPGPPGGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGGSWERRQAGSGGGGSWERRHPGPNPLDPQDPSPDAYCNLVILAVANRDAAEESCALICQVFQIIYGDQSIECVDRAGYHYTSTPERPWLCSRSESCHTDGTYAYDADFSCCSSFNGSQDTFEACYSGTSTPSFHGSHCSGSDHSSLGLEQLQDYMVTLRSKLGPLEIQQFAMLLREYRLGLPIQDYCTGLLKLYGDRRKFLLLGMRPFIPDQDIGYFEGFLEGVGIREGGILTDSFGRIKRSMSSTSASAVRSYDGAAQRPEAQAFHRLLADITHDIEALAPDDDDDDEDEPRGSRGGSDAAEDNYL", "length": 571 }, "evidence": [ { "id": "E1BN45", "url": "https://omabrowser.org/oma/group/E1BN45/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "heart morphogenesis", "id": "GO:0003007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003007", "evidence": [ { "database": "UniProtKB", "id": "E1BN45", "url": "https://www.uniprot.org/uniprotkb/E1BN45" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 377, "end_pos": 379, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BN45-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 568, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BN45-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BN45" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BN45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN45" }, { "id": "PF16545", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16545" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cerebral cavernous malformations 2 harmonin-homology", "eco_id": "ECO_0000259", "start_pos": 401, "end_pos": 500, "start_aa": "Ser", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 377, "end_pos": 379 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BN46-1", "uniprot_ac": "E1BN46", "uniprot_id": "E1BN46_BOVIN", "mass": { "chemical_mass": 41364.0, "monoisotopic_mass": 41364.0 }, "refseq": { "ac": "NP_001192380", "name": "G-protein coupled receptor 87", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192380" }, "gene_names": [ { "name": "GPR87", "type": "recommended", "evidence": [ { "id": "E1BN46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN46" } ] }, { "name": "GPR87", "type": "synonym", "evidence": [ { "id": "NP_001192380", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192380" } ] } ], "protein_names": [ { "name": "G protein-coupled receptor 87", "type": "synonym", "evidence": [ { "id": "E1BN46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN46/entry#names_and_taxonomy" } ] }, { "name": "G-protein coupled receptor 87", "type": "synonym", "evidence": [ { "id": "NP_001192380", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192380" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BN46", "url": "https://www.uniprot.org/uniprotkb/E1BN46" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GPR87", "url": "https://www.uniprot.org/uniprotkb/E1BN46", "locus": { "chromosome": "1", "start_pos": 116798062, "end_pos": 116781560, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011192", "url": "https://www.ensembl.org/id/ENSBTAG00000011192" } ] } } ], "crossref": [ { "id": "E1BN46", "url": "https://alphafold.ebi.ac.uk/entry/E1BN46", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011192", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011192", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15969", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15969", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "785030", "url": "https://www.ncbi.nlm.nih.gov/gene/785030", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:785030", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:785030", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VVYINTC", "url": "https://omabrowser.org/oma/group/VVYINTC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BN46", "url": "https://www.orthodb.org/?gene=E1BN46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24233", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24233", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24233:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24233:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192380", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192380", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BN46", "url": "https://www.uniprot.org/uniprotkb/E1BN46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN46-1", "url": "https://www.uniprot.org/uniprotkb/E1BN46-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLNLTLAKLPDNELHGPGNHTPSNTSDGSGKNTTVHNEFDTIVLPGLYLVIFVASILLNGLAVWIFFHIRNKTSFIFYLKNIVVADLIMTLTFPFRIVHDAGLGPWYFKFILCRYSSVLFYANMYTSIVFLGLISIDRYLKVVKPFGDSRMYSITFTKVLSVCVWVLMAVLSLPNIILTNVQPTRENIHECTKLKSPLGVKWHNAITYVNSCLFVVVLVILIGCYIAISRYIHKSSRQFISQSSRKRKHNQSIRVVVAVFFTCFLPYHLCRIPFTFSHLDRLLDESAHKILYYCKEMTLFLSACNVCLDPIIYFFMCRSFSRRLFKKSNIRTRSESIRSLQSVRRSEVRIYYDYTDV", "length": 358, "header": "tr|E1BN46-1|E1BN46_BOVIN Isoform 1 of G protein-coupled receptor 87 OS=Bos taurus OX=9913 GN=GPR87 PE=3 SV=1 CANONICAL=E1BN46-1" }, "isoforms": [ { "isoform_ac": "E1BN46-1", "url": "https://www.uniprot.org/uniprotkb/E1BN46/entry", "sequence": { "sequence": "MGLNLTLAKLPDNELHGPGNHTPSNTSDGSGKNTTVHNEFDTIVLPGLYLVIFVASILLNGLAVWIFFHIRNKTSFIFYLKNIVVADLIMTLTFPFRIVHDAGLGPWYFKFILCRYSSVLFYANMYTSIVFLGLISIDRYLKVVKPFGDSRMYSITFTKVLSVCVWVLMAVLSLPNIILTNVQPTRENIHECTKLKSPLGVKWHNAITYVNSCLFVVVLVILIGCYIAISRYIHKSSRQFISQSSRKRKHNQSIRVVVAVFFTCFLPYHLCRIPFTFSHLDRLLDESAHKILYYCKEMTLFLSACNVCLDPIIYFFMCRSFSRRLFKKSNIRTRSESIRSLQSVRRSEVRIYYDYTDV", "length": 358, "header": "tr|E1BN46-1|E1BN46_BOVIN Isoform 1 of G protein-coupled receptor 87 OS=Bos taurus OX=9913 GN=GPR87 PE=3 SV=1 CANONICAL=E1BN46-1" }, "locus": { "chromosome": "1", "start_pos": 116797979, "end_pos": 116791506, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014864.4", "url": "https://www.ensembl.org/id/ENSBTAT00000014864.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014864.3", "url": "https://www.ensembl.org/id/ENSBTAP00000014864.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:785030", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:785030", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AN17-1", "protein_name": "G protein-coupled receptor 87", "gene_name": "GPR87", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGLNVTLAKLPDNELPSPRNHTPSNVSDAPGKNATINNEFNTIVLPLLYLVIFVASILLNGLAVWIFFHIRNKTSFIFYLKNIVVADLIMTLTFPFRIVHDAGFGPWYFKFILCRYTSVLFYANMYTSIVFLGLISIDRYLKVVKPFGDSRMYSVTFTKVLSICVWVLMAVLSLPNIILTNGQPTRENIHECVKLKSPLGVKWHNAIIYVNSCLFVAVLVILIGCYIAISRYIHKSSRQFISQSSRKRKHNQSIRVVVAVFFTCFLPYHLCRIPFTFSHLDRLLDDSAHKILYYCKEMTLFLSACNVCLDPIIYFFMCRSFSRRLFKKSNIRTRSESIRSLQSVRRSEVRIYYDYTDV", "length": 358 }, "evidence": [ { "id": "E1BN46", "url": "https://omabrowser.org/oma/group/E1BN46/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2QDE6-1", "protein_name": "G-protein coupled receptor 87", "gene_name": "Gpr87", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLNLTLARLPSNELYSQASHSANSTSVGRWKNSTHHNEFDTIILPVLYLVIFVASILLNGLAVWIFFHIRNKTSFIFYLKNIVVADLIMTMTFPFRIVRDSGFGPWYIEFILCRYTSVLFYANMYTSIVFLGLISVDRYLKVVKPFGDSRMYSITFTKVLSICVWVVMAVLSLPNIILTNGQPTKENIHDCMKLKNPLGAKWHMAVTYVDSCLFVAVLVILIGCYIAISRYIHKSSRQFISQSSRKRKHNQSIRVVVAVFFTCFLPYHLCRIPFTFSHLDRLLDESAHKILYYCKEMTLFLSACNVCLDPIIYFFMCRSFSRRLFKKSNIRTRSESIRSLQSVRRSEVRIYYDYTDV", "length": 358 }, "evidence": [ { "id": "E1BN46", "url": "https://omabrowser.org/oma/group/E1BN46/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0X448-1", "protein_name": "G protein-coupled receptor 87", "gene_name": "GPR87", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGYNLSYGPLPEEHLSAVASAAPNRSVGPPGNTTQDEFTTIVLPVLYLVIFLASILLNGLAVWIFFHIRNKTSFIFYLKNIVVADLLMTLTFPFKIIQDSQLGPWHFNSFLCRYTTVLFYANMYTTIVFLGLISIDRYLKVVKPFGDSRMYSITFTKVLSACVWVVMAFLALPNLILTNGYPTRRNIDDCIKLKSPLGVKWHTAVIYINTCTFMVVLVVLIGCYIAISRYIYKSSKQFISSSSRKRKHNQSIRVVVAVFFTCFLPYHLCRIPFTFSHLDKLLDDSAHKILYYCKEMTLFLSACNVCLDPIIYFFMCRSFSRRLFRKSNMRTRSESIRSLQSVRRSEVRIYHEYTDV", "length": 356 }, "evidence": [ { "id": "E1BN46", "url": "https://omabrowser.org/oma/group/E1BN46/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1LXU3-1", "protein_name": "G protein-coupled receptor 87", "gene_name": "Gpr87", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLNLTLAKLPGNELYSQASHTANSTIEGHGKNSTHHNEFDTIILPVLYLVIFVASILLNGLAVWIFFHIRNKTSFIFYLKNIVVADLIMTLTFPFRIVRDAGFGPWYFEFILCRYTSVLFYANMYTSIVFLGLISVDRYLKVVKPFGDSRMYSITFTKVLSICVWVIMAVLSLPNIILTNGQPTKENIHDCMKLKSPLGAKWDMAVTYVDSCLFVAVLVILIGCYIAISRYIHKSSRQFISQSSRKRKHNQSIRVVVAVFFTCFLPYHLCRIPFTFSHLDRLLDDSAHKILHYCKEMTLFLSACNVCLDPIIYFFMCKSFSRRLFKKSNIRTRSESIRSLQSVRRSEVRIYYDYTDV", "length": 358 }, "evidence": [ { "id": "E1BN46", "url": "https://omabrowser.org/oma/group/E1BN46/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99MT7-1", "protein_name": "G protein-coupled receptor 87", "gene_name": "Gpr87", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLNLTLTKLPGNELYSQASHTANSTSEGHGKNSTLHNKFDTIILPVLYLVIFVASILLNGLAVWIFFHIRNKTSFIFYLKNIVVADLIMTLTFPFRIVRDAGFGPWYFEFILCRYTSVLFYANMYTSIVFLGLISVDRYLKVVKPFGDSRMYSITFTKVLSVCVWVIMAILSLPNIILTNGQPTKENIHDCMKLKSPLGAKWHMAVTYVDSCLFVAVLVILIGCYIAISRYIHKSSRQFISQSSRKRKHNQSIRVVVAVFFTCFLPYHLCRIPFTFSNLDRLLDESAHKILYYCKEMTLFLSACNVCLDPIIYFFMCKSFSRRLFKKSNIRTRSESIRSLQSVRRSEVRIYYDYTDV", "length": 358 }, "evidence": [ { "id": "E1BN46", "url": "https://omabrowser.org/oma/group/E1BN46/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BY21-1", "protein_name": "G protein-coupled receptor 87", "gene_name": "GPR87", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGFNLTLAKLPNNELHGQESHNSGNRSDGPGKNTTLHNEFDTIVLPVLYLIIFVASILLNGLAVWIFFHIRNKTSFIFYLKNIVVADLIMTLTFPFRIVHDAGFGPWYFKFILCRYTSVLFYANMYTSIVFLGLISIDRYLKVVKPFGDSRMYSITFTKVLSVCVWVIMAVLSLPNIILTNGQPTEDNIHDCSKLKSPLGVKWHTAVTYVNSCLFVAVLVILIGCYIAISRYIHKSSRQFISQSSRKRKHNQSIRVVVAVFFTCFLPYHLCRIPFTFSHLDRLLDESAQKILYYCKEITLFLSACNVCLDPIIYFFMCRSFSRRLFKKSNIRTRSESIRSLQSVRRSEVRIYYDYTDV", "length": 358 }, "evidence": [ { "id": "E1BN46", "url": "https://omabrowser.org/oma/group/E1BN46/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BN46", "url": "https://www.uniprot.org/uniprotkb/E1BN46" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "E1BN46", "url": "https://www.uniprot.org/uniprotkb/E1BN46" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled purinergic nucleotide receptor activity", "id": "GO:0045028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045028", "evidence": [ { "database": "UniProtKB", "id": "E1BN46", "url": "https://www.uniprot.org/uniprotkb/E1BN46" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" }, { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" }, { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" }, { "start_pos": 33, "end_pos": 35, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BN46-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 358, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BN46-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BN46" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 20, "end_pos": 22 }, { "start_pos": 251, "end_pos": 253 }, { "start_pos": 25, "end_pos": 27 }, { "start_pos": 33, "end_pos": 35 }, { "start_pos": 4, "end_pos": 6 }, { "start_pos": 72, "end_pos": 74 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BN72-1", "uniprot_ac": "E1BN72", "uniprot_id": "E1BN72_BOVIN", "mass": { "chemical_mass": 49418.0, "monoisotopic_mass": 49418.0 }, "refseq": { "ac": "NP_001192904", "name": "serine/threonine-protein kinase NIM1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192904" }, "gene_names": [ { "name": "NIM1K", "type": "recommended", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "name": "NIM1K", "type": "synonym", "evidence": [ { "id": "NP_001192904", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192904" } ] }, { "name": "NIM1", "type": "synonym", "evidence": [ { "id": "NP_001192904", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192904" } ] } ], "protein_names": [ { "name": "Serine/threonine-protein kinase NIM1", "type": "recommended", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72/entry#names_and_taxonomy" } ] }, { "name": "NIM1 serine/threonine-protein kinase", "type": "synonym", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72/entry#names_and_taxonomy" } ] }, { "name": "serine/threonine-protein kinase NIM1", "type": "synonym", "evidence": [ { "id": "NP_001192904", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192904" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BN72", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NIM1K", "url": "https://www.uniprot.org/uniprotkb/E1BN72", "locus": { "chromosome": "20", "start_pos": 31464678, "end_pos": 31491156, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006233", "url": "https://www.ensembl.org/id/ENSBTAG00000006233" } ] } } ], "crossref": [ { "id": "E1BN72", "url": "https://alphafold.ebi.ac.uk/entry/E1BN72", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006233", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006233", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14075", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14075", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "530210", "url": "https://www.ncbi.nlm.nih.gov/gene/530210", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:530210", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:530210", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IMSNEWM", "url": "https://omabrowser.org/oma/group/IMSNEWM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BN72", "url": "https://www.orthodb.org/?gene=E1BN72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24346", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24346", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24346:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24346:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192904", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192904", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BN72", "url": "https://www.uniprot.org/uniprotkb/E1BN72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN72-1", "url": "https://www.uniprot.org/uniprotkb/E1BN72-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTAVYVNGGGLVNPHCARWGRRESEESGCQTECAKEDEEGEPRQLTPFEKLTQDMSQDEKVVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISMEGKFSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTNNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYVGVYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCLRLIRGVLQPVPAERYGIDSIMNNEWMQGVPYPTPLEPFQLDPKHLSETSSLKEEENEVKSTLEHLGITEEHIRNNQGRDARSSITGVYRIILHRVQKKKALESVPIMILPDPKDKDLKKGSRVYRGIRHTSKFCSIL", "length": 436, "header": "tr|E1BN72-1|E1BN72_BOVIN Isoform 1 of Serine/threonine-protein kinase NIM1 OS=Bos taurus OX=9913 GN=NIM1K PE=3 SV=1 CANONICAL=E1BN72-1" }, "isoforms": [ { "isoform_ac": "E1BN72-1", "url": "https://www.uniprot.org/uniprotkb/E1BN72/entry", "sequence": { "sequence": "MTAVYVNGGGLVNPHCARWGRRESEESGCQTECAKEDEEGEPRQLTPFEKLTQDMSQDEKVVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISMEGKFSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTNNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYVGVYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCLRLIRGVLQPVPAERYGIDSIMNNEWMQGVPYPTPLEPFQLDPKHLSETSSLKEEENEVKSTLEHLGITEEHIRNNQGRDARSSITGVYRIILHRVQKKKALESVPIMILPDPKDKDLKKGSRVYRGIRHTSKFCSIL", "length": 436, "header": "tr|E1BN72-1|E1BN72_BOVIN Isoform 1 of Serine/threonine-protein kinase NIM1 OS=Bos taurus OX=9913 GN=NIM1K PE=3 SV=1 CANONICAL=E1BN72-1" }, "locus": { "chromosome": "20", "start_pos": 31490468, "end_pos": 31464795, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008181.4", "url": "https://www.ensembl.org/id/ENSBTAT00000008181.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008181.2", "url": "https://www.ensembl.org/id/ENSBTAP00000008181.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 332, "start_aa": "Thr", "end_pos": 332, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr332", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:530210", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:530210", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YNI5-1", "protein_name": "Serine/threonine-protein kinase NIM1", "gene_name": "NIM1K", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNQRKTQCSAFGLVPESGATFLSVCYVRDCILTEKYFTSLNSLLGHFVQWRSDYLQTMTTGFVNGGGLGKHRYARWNREDSGEDYGREECCGGDEEGRQQRLTPLEKLMQDMSHNEKVVKELTLGKRIGFYRVRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFTKITTEGKLIETDCKIIFSQIVSAVKHMHENNIIHRDLKAENVFYTSNTCVKVGDFGFSTISKRDETLNTFCGSPPYAAPELFRDENYVGIYVDIWALGILLYFMITGIMPFRADTVAKLKKCILEGTYSLPPCLSEACQKLIKGVLQPVPTERYSVKLIMNSEWMQGIQYPKPLQPFKLDPKYLSEISTLKEEEIEVKNALKDLGITEEHIKNNQGRDARSSITGVYRIVLHKVQKKRALECVPIMSHPDPKEQDIKKGISSCNGVKHTSKLCSIL", "length": 493 }, "evidence": [ { "id": "E1BN72", "url": "https://omabrowser.org/oma/group/E1BN72/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A9H8-1", "protein_name": "Serine/threonine-protein kinase NIM1", "gene_name": "Nim1k", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTAVVVNGGGLVNTHCDRWDRRDSAEGSCQTEGSKDGEEDQPRQLTPFEKLTQDMCQDEKVVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIVRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSSTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYVGVYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGAYSIPQHVSEPCHRLIRGVLQPTPAERYGINYIMSNEWMRGVPYPSPLEPFQLDPKHLSETSTLKEEENEVKSTLEHLGITDEHIRNNQGRDARSSITGVYRIILHRVQRRKALESVPMATLPEPKDKDLKKGSRVYRGIRHTSKFCSIL", "length": 436 }, "evidence": [ { "id": "E1BN72", "url": "https://omabrowser.org/oma/group/E1BN72/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SMG7-1", "protein_name": "Serine/threonine-protein kinase NIM1", "gene_name": "NIM1K", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMTAVYVNGGSLVNSHYARWDRRESVESGCQTECNKEDEEGQPRQLTPFEKLMQDMSQDEKVVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKFSESESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYVGIYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCLRLIRGVLQPVPTERYGIDSIMNNEWMQGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTLEHLGITEEHIRNNQGRDARSSITGVYRIILHRVQKKKALESVPIMILPDPKERDLKKGSRVYRGIRHTSKFCSIL", "length": 437 }, "evidence": [ { "id": "E1BN72", "url": "https://omabrowser.org/oma/group/E1BN72/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HMY1-1", "protein_name": "Serine/threonine-protein kinase NIM1", "gene_name": "Nim1k", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTAVFANGGGLVNTHCDRWDRRDSVESSCQTECGQEGEEDQPRQLTPFEKLTQDMCQDEKVVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSSTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGVYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSIPQHVSEPCHRLIRGVLQPIPTERYGISYIMNNEWMRGVPYPTPLQPFQLDPKHLSEASSLEEEENEVKSTLEHLGITDEHIRNNPGRDARSSITGVYRIILHRVQRKKALESVPIMILPEPKERDLKKGSRIYRGIRHTSKFCSIL", "length": 436 }, "evidence": [ { "id": "E1BN72", "url": "https://omabrowser.org/oma/group/E1BN72/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8BHI9-1", "protein_name": "Serine/threonine-protein kinase NIM1", "gene_name": "Nim1k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTAVFVNGGGLVNTHCDRWERRDSVESSCQTEGGKDSEEDQQRQLTPFEKLTQDMCQDEKVVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIVRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDQHYVGVYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYTIPQHVSEPCHRLIRGVLQPTPTERYGINYIMSNEWMRGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTLEHLGITDEHIRNNQGRDARSSITGVYRIILHRVQRRKALESVPIMILPEPKERDLKKGSRIYRGIRHTSKFCSIL", "length": 436 }, "evidence": [ { "id": "E1BN72", "url": "https://omabrowser.org/oma/group/E1BN72/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IY84-1", "protein_name": "Serine/threonine-protein kinase NIM1", "gene_name": "NIM1K", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTAVYMNGGGLVNPHYARWDRRDSVESGCQTESSKEGEEGQPRQLTPFEKLTQDMSQDEKVVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGIYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIPTERYGIDCIMNDEWMQGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTLEHLGITEEHIRNNQGRDARSSITGVYRIILHRVQRKKALESVPVMMLPDPKERDLKKGSRVYRGIRHTSKFCSIL", "length": 436 }, "evidence": [ { "id": "E1BN72", "url": "https://omabrowser.org/oma/group/E1BN72/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "E1BN72", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "E1BN72", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BN72", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "E1BN72", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0A3Q1MLK5-1", "A0AAF6Z257-1", "F6RPH3-1", "F1MC27-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "F1N332-1", "A7MB74-1", "A0AAA9RW51-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A1A4I4-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "Q3SWY6-1", "A0AAA9T5C9-1", "A7E3S4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P32871-1", "P35508-1", "P67827-1", "P04409-1", "P05126-1", "P05128-1", "P46196-1", "H2XJE9-1", "Q0VD22-1", "Q2KJG8-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "Q2YDN8-1", "A0AAA9SK35-1", "A0AAA9RSJ2-1", "A0AAA9T7I8-1", "Q3T0P6-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "F6PN06-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9RTJ4-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0AAA9TCI9-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "E1BEI6-1", "A0A3Q1M1Z0-1", "F1MYM3-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1MI36-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0A3Q1NFM1-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "E1BEW4-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "Q5E9Y9-1", "A0ABI0NMT8-1", "A0ABI0NRQ5-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0AAA9U136-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "E1BEW4-1", "A0AAA9SK35-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "A0AAA9T3H7-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0AAF6Z257-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "E1BEI6-1", "F1N332-1", "A7MB74-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "P67827-1", "P05126-1", "F6RPH3-1", "A0AAA9T5C9-1", "Q3SWY6-1", "A7E3S4-1", "A1A4I4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "F6PN06-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A0A3Q1N9F5-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P35508-1", "P46196-1", "P04409-1", "P05128-1", "H2XJE9-1", "Q0VD22-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "E1BI47-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B7L9-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "A0A3Q1MI36-1", "A0AAA9RSJ2-1", "A0A3Q1NFM1-1", "A0AAA9T7I8-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0A3Q1MLK5-1", "A0AAA9TCI9-1", "F1MC27-1", "A0AAA9RW51-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "A0A3Q1M1Z0-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "A0ABI0NRQ5-1", "F1MDS3-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LGC2", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] } ] }, { "uniprot_ac": "A0A3Q1LH95", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] } ] }, { "uniprot_ac": "A0A3Q1LJU7", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] } ] }, { "uniprot_ac": "A0A3Q1LKG0", "gene_name": "MINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] } ] }, { "uniprot_ac": "A0A3Q1LL42", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] } ] }, { "uniprot_ac": "A0A3Q1LLF0", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] } ] }, { "uniprot_ac": "A0A3Q1LLH8", "gene_name": "CDK15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] } ] }, { "uniprot_ac": "A0A3Q1LM61", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] } ] }, { "uniprot_ac": "A0A3Q1LN49", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] } ] }, { "uniprot_ac": "A0A3Q1LNA9", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] } ] }, { "uniprot_ac": "A0A3Q1LNU2", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] } ] }, { "uniprot_ac": "A0A3Q1LQP3", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] } ] }, { "uniprot_ac": "A0A3Q1LR28", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] }, { 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"id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] } ] }, { "uniprot_ac": "A0A3Q1LU59", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LU59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU59" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LU59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU59" } ] } ] }, { "uniprot_ac": "A0A3Q1LW88", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LW88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LW88", "database": "UniProtKB", "url": 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"url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] } ] }, { "uniprot_ac": "Q3SYZ2", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] } ] }, { "uniprot_ac": "Q3SZJ2", "gene_name": "RIPK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] } ] }, { "uniprot_ac": "Q3SZW1", "gene_name": "TSSK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] } ] }, { "uniprot_ac": "Q3T0N5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] } ] }, { "uniprot_ac": "Q3T0P6", "gene_name": "PGK1", "activity": [ { "ec_number": "2.7.2.3", "activity": "(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP.", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.2.3", "activity": "", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] } ] }, { "uniprot_ac": "Q4TVR5", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q4TVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4TVR5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q4TVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4TVR5" } ] } ] }, { "uniprot_ac": "Q58D94", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q58D94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58D94" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q58D94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58D94" } ] } ] }, { "uniprot_ac": "Q5E9L6", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5E9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9L6" } ] } ] }, { "uniprot_ac": "Q5E9X2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9X2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q5E9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9X2" } ] } ] }, { "uniprot_ac": "Q5E9Y0", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5E9Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y0" } ] } ] }, { "uniprot_ac": "Q5E9Y9", "gene_name": "NME7", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] } ] }, { "uniprot_ac": "Q5EAB2", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.22", "activity": "", 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47499", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47499:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47499:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00050", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00050", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BNB0", "url": "https://www.uniprot.org/uniprotkb/E1BNB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNB0-1", "url": "https://www.uniprot.org/uniprotkb/E1BNB0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADAVVVTILSNLCITAVSIMKTTGGLLLLCVVAHLCSCSEAASLPLKTDILLRMLQVNCSIYKKYPVVAIPCPITYLPVCGSDYITYGNECHLCIENLKSYGKVQFLHEGVC", "length": 113, "header": "tr|E1BNB0-1|E1BNB0_BOVIN Isoform 1 of Serine peptidase inhibitor Kazal type 7 OS=Bos taurus OX=9913 GN=SPINK7 PE=4 SV=4 CANONICAL=E1BNB0-1" }, "isoforms": [ { "isoform_ac": "E1BNB0-1", "url": "https://www.uniprot.org/uniprotkb/E1BNB0/entry", "sequence": { "sequence": "MADAVVVTILSNLCITAVSIMKTTGGLLLLCVVAHLCSCSEAASLPLKTDILLRMLQVNCSIYKKYPVVAIPCPITYLPVCGSDYITYGNECHLCIENLKSYGKVQFLHEGVC", "length": 113, "header": "tr|E1BNB0-1|E1BNB0_BOVIN Isoform 1 of Serine peptidase inhibitor Kazal type 7 OS=Bos taurus OX=9913 GN=SPINK7 PE=4 SV=4 CANONICAL=E1BNB0-1" }, "locus": { "chromosome": "7", "start_pos": 59723486, "end_pos": 59719585, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061218.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061218.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053591.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053591.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", 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"https://www.ebi.ac.uk/QuickGO/term/GO:0045861", "evidence": [ { "database": "UniProtKB", "id": "E1BNB0", "url": "https://www.uniprot.org/uniprotkb/E1BNB0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNB0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 113, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNB0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNB0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BNB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNB0" }, { "id": "PS51465", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51465" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kazal-like", "eco_id": "ECO_0000259", "start_pos": 54, "end_pos": 113, "start_aa": "Arg", "end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 59, "end_pos": 61 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "E1BNB2-1", "uniprot_ac": "E1BNB2", "uniprot_id": "E1BNB2_BOVIN", "mass": { "chemical_mass": 56271.0, "monoisotopic_mass": 56271.0 }, "refseq": { "ac": "NP_001192625", "name": "alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192625" }, "gene_names": [ { "name": "MGAT4C", "type": "recommended", "evidence": [ { "id": "E1BNB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNB2" } ] }, { "name": "MGAT4C", "type": "synonym", "evidence": [ { "id": "NP_001192625", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192625" } ] } ], "protein_names": [ { "name": "MGAT4 family member C", "type": "synonym", "evidence": [ { "id": "E1BNB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNB2/entry#names_and_taxonomy" } ] }, { "name": "alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C", "type": "synonym", "evidence": [ { "id": "NP_001192625", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192625" } ] }, { "name": "mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)", "type": "synonym", "evidence": [ { "id": "NP_001192625", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192625" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BNB2", "url": "https://www.uniprot.org/uniprotkb/E1BNB2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MGAT4C", "url": "https://www.uniprot.org/uniprotkb/E1BNB2", "locus": { "chromosome": "5", "start_pos": 15663357, "end_pos": 15743103, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011153", "url": "https://www.ensembl.org/id/ENSBTAG00000011153" } ] } } ], "crossref": [ { "id": "E1BNB2", "url": "https://alphafold.ebi.ac.uk/entry/E1BNB2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011153", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011153", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "539661", "url": "https://www.ncbi.nlm.nih.gov/gene/539661", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006759", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006759", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056576", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056576", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057279", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057279", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539661", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539661", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MTDVEHK", "url": "https://omabrowser.org/oma/group/MTDVEHK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BNB2", "url": "https://www.orthodb.org/?gene=E1BNB2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12062", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12062", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12062:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12062:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04666", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04666", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23524", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23524", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-975577", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975577", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192625", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192625", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BNB2", "url": "https://www.uniprot.org/uniprotkb/E1BNB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNB2-1", "url": "https://www.uniprot.org/uniprotkb/E1BNB2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLKFHQVKHIFDILDKMRCLRKRSTVSFLGVLVIFLLFMNLYIEDSYVMEGDKQILRETSTHQLSPEHYMHTFKDLSNFSGALNVTYRYLAVMPLQRKRFLTIGLSSVRRKKGSYLLETIKSIFEQSSYEELKELSVVVHLADFNSSWREVMLQDITQKFAHHIIAGRLMVIHAPEEYYPILSGLKRNYNDPEDRVRFRSKQNVDYAFLLNFCANISYYYVMLEDDVRCSKNFLTAIKKVIASLEGTYWVTLEFSKLGYIGKLYHSHDLPRLAHFLLMFYQEMPCDWLLTHFRSLLAQKNVIRFKPSLFQHMGYYSSYKGTENKLKDDDFEEEPFDLPDNPPASLYTNMSVFENYDASKAYSSVDDYFWGKPPSTGDVFVIIFEKPIVIKRIKVNTGTEDRQNDILHHGALDVGGNIRYFKQNRQCVTYIKLGEFRNGNFEVSDVNQKIPFDIHCMRIYVTKTQKEWLIIRSISIWTS", "length": 478, "header": "tr|E1BNB2-1|E1BNB2_BOVIN Isoform 1 of MGAT4 family member C OS=Bos taurus OX=9913 GN=MGAT4C PE=4 SV=3 CANONICAL=E1BNB2-1" }, "isoforms": [ { "isoform_ac": "E1BNB2-1", "url": "https://www.uniprot.org/uniprotkb/E1BNB2/entry", "sequence": { "sequence": "MLKFHQVKHIFDILDKMRCLRKRSTVSFLGVLVIFLLFMNLYIEDSYVMEGDKQILRETSTHQLSPEHYMHTFKDLSNFSGALNVTYRYLAVMPLQRKRFLTIGLSSVRRKKGSYLLETIKSIFEQSSYEELKELSVVVHLADFNSSWREVMLQDITQKFAHHIIAGRLMVIHAPEEYYPILSGLKRNYNDPEDRVRFRSKQNVDYAFLLNFCANISYYYVMLEDDVRCSKNFLTAIKKVIASLEGTYWVTLEFSKLGYIGKLYHSHDLPRLAHFLLMFYQEMPCDWLLTHFRSLLAQKNVIRFKPSLFQHMGYYSSYKGTENKLKDDDFEEEPFDLPDNPPASLYTNMSVFENYDASKAYSSVDDYFWGKPPSTGDVFVIIFEKPIVIKRIKVNTGTEDRQNDILHHGALDVGGNIRYFKQNRQCVTYIKLGEFRNGNFEVSDVNQKIPFDIHCMRIYVTKTQKEWLIIRSISIWTS", "length": 478, "header": "tr|E1BNB2-1|E1BNB2_BOVIN Isoform 1 of MGAT4 family member C OS=Bos taurus OX=9913 GN=MGAT4C PE=4 SV=3 CANONICAL=E1BNB2-1" }, "locus": { "chromosome": "5", "start_pos": 15674190, "end_pos": 15663360, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014809.4", "url": "https://www.ensembl.org/id/ENSBTAT00000014809.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014809.3", "url": "https://www.ensembl.org/id/ENSBTAP00000014809.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539661", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539661", "resource": "KEGG Pathway" }, { "id": "R-BTA-975577", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975577", "resource": "Reactome", "description": "N-Glycan antennae elongation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AS89-1", "protein_name": "MGAT4 family member C", "gene_name": "MGAT4C", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFKFHQVKHIFEILDKMRCLRKRFTVSFLGVLVIFLLFMNLYIEDSYVLEGDKQLVRETSIHQLNPERYVHTFKYLSNFSGTINVTYRYLAVMPFQRKRFLTIGLSSVRRKKGNYLLETIKSIFEQSSYEELKEISVVVHLADFNSSWREVMVQDITQKFAHHIIAGRLMVIHAPEEYYPLNGLKRNYNDPEDRVRFRSKQNVDYAFLLNFCANISDYYVMLEDDVRCSKNFLTAIKKVITSLQGTYWVTLEFSKLGYIGKLYHSHDLPRLAHFLLMFYQEMPCDWLLTHFRGLLAQKNVIRFKPSLFQHMGYYSSYKGTENKLKDDDFEEELIDLPDNPPASLYTNMSVFENYDASKAYSSVDGYFWGKPPSTGDVFVVVFENPVIIKKIKVSTGTEDRQNDILHHGALDVGGYIRYFKQNRQCITYIRLGEFKNGNFEVSDVNQKIPFDVHCMRIHVTKTQKEWLIIRSISIWTS", "length": 477 }, "evidence": [ { "id": "E1BNB2", "url": "https://omabrowser.org/oma/group/E1BNB2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZEV3-1", "protein_name": "MGAT4 family, member C", "gene_name": "Mgat4c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFKFYQMKYIFQILDKMRCLRKRSTVSFLGVLVVFLLFMNVFIEDSYVLEGDKQLIRETSTHQLNSERYVHTFKDLSNFSGTINVTYRYLAATPLQRKRYLTIGLSSVKRKKGNYLLETIKSIFEQSSYEELKEISVVVHLADFNSSWRDAMVQDITQKFAHHIIAGRLMVIHAPEEYYPVLDGLKRNYNDPEDRVRFRSKQNVDYAFLLNFCANTSDYYVMLEDDVRCSRNFLTAIKKVIASLEGTYWVTLEFSKLGYIGKLYHSHDLPRLAHFLLMFYQEMPCDWLLTHFRGLLAQKNVIRFKPSLFQHMGYYSSYKGTENKLKDDDFEEESFDIPDNPPASLYTNMNVFENYEASKAYSSVDEYFWGKPPSTGDTFVIVFENPIKIKKIKVNTGTEDRQNDILHHGALDVGEKLIFSKQIRQCETYLRLGEFKNGNFEMSDVNQKIPFDIHCMRICVTKTQKEWLIIRSISIWTS", "length": 478 }, "evidence": [ { "id": "E1BNB2", "url": "https://omabrowser.org/oma/group/E1BNB2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D306-1", "protein_name": "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C", "gene_name": "Mgat4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLKFYQMKYIFQILDKMRCLRKRSTVSFLGVLVVFLLFMNLYIEDSYVLEGDKQLIRETSTHQLNSERYVHTFKDLSNFSGTINVTYRYLAATPLQRKRYLTIGLSSVKRKKGNYLLDTIKSIFEQSSYEELKEISVVVHLADFNSSWRDAMVQDITQKFAHHIIAGRLMVIHAPEEYYPVLDGLKRNYNDPEDRVRFRSKQNVDYAFLLNFCANTSDYYVMLEDDVRCSRNFLTAIKKVIASLEGTYWVTLEFSKLGYIGKLYHSHDLPRLAHFLLMFYQEMPCDWLLTHFRGLLAQKNVIRFKPSLFQHMGYYSSYKGTENKLKDDDFEEESFDIPDNPPASFYTNMNVFENYEASKAYSSVDEYFWGKSPSMGDTFVIVFENPITIKKIKVNTGTEDRQNDILQHGALDVGEKLIFSKQIRQCDTYLRLGEFKNGYFEMSDVNQKIPFDIHCMRICVTKTQKEWLIIRSISIWTS", "length": 478 }, "evidence": [ { "id": "E1BNB2", "url": "https://omabrowser.org/oma/group/E1BNB2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UBM8-1", "protein_name": "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C", "gene_name": "MGAT4C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFKFHQMKHIFEILDKMRCLRKRSTVSFLGVLVIFLLFMNLYIEDSYVLEGDKQLIRETSTHQLNSERYVHTFKDLSNFSGAINVTYRYLAATPLQRKRYLTIGLSSVKRKKGNYLLETIKSIFEQSSYEELKEISVVVHLADFNSSWRDAMVQDITQKFAHHIIAGRLMVIHAPEEYYPILDGLKRNYNDPEDRVKFRSKQNVDYAFLLNFCANTSDYYVMLEDDVRCSKNFLTAIKKVIASLEGTYWVTLEFSKLGYIGKLYHSHDLPRLAHFLLMFYQEMPCDWLLTHFRGLLAQKNVIRFKPSLFQHMGYYSSYKGTENKLKDDDFEEESFDIPDNPPASLYTNMNVFENYEASKAYSSVDEYFWGKPPSTGDVFVIVFENPIIIKKIKVNTGTEDRQNDILHHGALDVGENVMPSKQRRQCSTYLRLGEFKNGNFEMSGVNQKIPFDIHCMRIYVTKTQKEWLIIRSISIWTS", "length": 478 }, "evidence": [ { "id": "E1BNB2", "url": "https://omabrowser.org/oma/group/E1BNB2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "R4GKF3-1", "protein_name": "MGAT4 family member C", "gene_name": "MGAT4C", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVTLPYAFLHMRHNLKYFDKMRCLRKRSAVSFLGVLVICLLFMNLYIEDGYVLEGDKQLIRETATHQLNPERYAHTYKDLSNFSGSINISYRYLAGTPLPRKRYLTIGLSSVKRKKGNYLLETIKSIFEQSSYEELKEITVVVQLADFDSGWCEGMVQDISQKFAHHIIAGRLIVIHVPEEFYPILDGLKRNYNDPEDRVKFRSKQNVDYAFLLNFCANLSDYYVMLEDDVRCSKNFLTTVKKVITSREGSYWVTLEFSKLGYIGKLYHSHDLPRLAHFLLMFYQEMPCDWLLIHFRGLLAQKEVIRFKPSLFQHMGYYSSYKGAENKLKDDDFEEESFDIPDNPPANLHTNMNVFENYEASKAYSSIDEYFWGKPPSTGDFYGIVFEKPIKISKIKVVTGTEDRQNDILRHGALEVGEKIVGSKIGRKCTTYLRLGEFKNGNFEMTDVEHKVLFDINCMRILVTKSQKEWLIIRSISIWTSQTSSQ", "length": 487 }, "evidence": [ { "id": "E1BNB2", "url": "https://omabrowser.org/oma/group/E1BNB2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "acetylglucosaminyltransferase activity", "id": "GO:0008375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008375", "evidence": [ { "database": "UniProtKB", "id": "E1BNB2", "url": "https://www.uniprot.org/uniprotkb/E1BNB2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "E1BNB2", "url": "https://www.uniprot.org/uniprotkb/E1BNB2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 348, "end_pos": 350, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BNB2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 478, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BNB2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BNB2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BNB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNB2" }, { "id": "PF23524", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23524" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MGAT4 A/B/C C-terminal", "eco_id": "ECO_0000259", "start_pos": 343, "end_pos": 471, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": [] }, { "evidence": [ { "id": "E1BNB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNB2" }, { "id": "PF04666", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04666" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MGAT4 conserved region", "eco_id": "ECO_0000259", "start_pos": 68, "end_pos": 330, "start_aa": "His", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [ { "glytoucan_ac": "G00152UP", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00176HZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00201AB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00210ZX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00212RH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00221CZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00231WL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00279YF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00349CA", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00361YF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00368HM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00369RM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00383YF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00413UF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00432WV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00451UT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00470UO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00471UP", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00480IB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00492CQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G00503EE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00514XC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00536FZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00584LL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00598SQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00606LX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00647HI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00670OT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00695JO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G00706AL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00706VT", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00727QV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00797ZX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00805TZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00817BI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00826SV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G00828CZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00883DO", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G00909GK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00909PI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00910WD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00915XC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00948WV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00955WX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00979HB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00982QD", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G00986YT", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G01001RL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01050GH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01051RR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01079TS", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G01092NQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01218JA", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01223AA", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01239JD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01244DB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01304ZB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01308XT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01310VF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01354KL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01359JE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01385UC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01416SG", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G01454UB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01521YU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01543ZX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01578LK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01613KN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01668VR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01669LU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01685IB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01733NS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01734XU", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G01803DO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01818TY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01827FA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01851EU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01891JS", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G01917CF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01923XE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01959AV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01962RN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01996OW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G02025MF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G02038EU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G02041MX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G02076VP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G02106OV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G02122FK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G02151HS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G02152MS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G02156UW", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G02174FQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G02175PZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G02183OE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G02193CV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G02207TG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G02284UY", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G02290KA", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G02296PF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G02311IE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G02335DL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G02429WR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G02470AU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G02471GW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G02474FD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G02483WT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G02513HF", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G02522GH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G02536WY", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G02630BJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G02654EL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G02681BC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G02684XX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G02686MD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G02786XX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G02812LT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G02987EY", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G03004PD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G03061OY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G03075ZE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G03096WL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G03142ET", "type": "N-linked", "subtype": "Tetraantennary" }, { 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"yes" } }, { "uniprot_canonical_ac": "E1BND0-1", "uniprot_ac": "E1BND0", "uniprot_id": "E1BND0_BOVIN", "mass": { "chemical_mass": 294175.0, "monoisotopic_mass": 294175.0 }, "refseq": { "ac": "XP_002686434", "name": "ubiquitin carboxyl-terminal hydrolase 24 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002686434" }, "gene_names": [ { "name": "USP24", "type": "recommended", "evidence": [ { "id": "E1BND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BND0" } ] }, { "name": "USP24", "type": "synonym", "evidence": [ { "id": "XP_002686434", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002686434" } ] } ], "protein_names": [ { "name": "Ubiquitin carboxyl-terminal hydrolase 24", "type": "recommended", "evidence": [ { "id": "E1BND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BND0/entry#names_and_taxonomy" } ] }, { "name": "3.4.19.12", "type": "synonym", "evidence": [ { "id": "E1BND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BND0/entry#names_and_taxonomy" } ] }, { "name": "Deubiquitinating enzyme 24", "type": "synonym", "evidence": [ { "id": "E1BND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BND0/entry#names_and_taxonomy" } ] }, { "name": "Ubiquitin thioesterase 24", "type": "synonym", "evidence": [ { "id": "E1BND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BND0/entry#names_and_taxonomy" } ] }, { "name": "Ubiquitin-specific-processing protease 24", "type": "synonym", "evidence": [ { "id": "E1BND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BND0/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin carboxyl-terminal hydrolase 24 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_002686434", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002686434" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "E1BND0", "url": "https://www.uniprot.org/uniprotkb/E1BND0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "USP24", "url": "https://www.uniprot.org/uniprotkb/E1BND0", "locus": { "chromosome": "3", "start_pos": 91285631, "end_pos": 91131329, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016990", "url": "https://www.ensembl.org/id/ENSBTAG00000016990" } ] } } ], "crossref": [ { "id": "ENSBTAG00000016990", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016990", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02659", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02659", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14286", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14286", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17065", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17065", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "532257", "url": "https://www.ncbi.nlm.nih.gov/gene/532257", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033382", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033382", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047061", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047061", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055176", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055176", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:532257", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532257", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LCCPVDN", "url": "https://omabrowser.org/oma/group/LCCPVDN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BND0", "url": "https://www.orthodb.org/?gene=E1BND0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24006", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24006", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24006:SF729", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24006:SF729", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00443", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00443", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22900", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22900", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_002686434", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002686434", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LYF8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LYF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1T8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1T8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1T8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BND0", "url": "https://www.uniprot.org/uniprotkb/E1BND0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BND0-1", "url": "https://www.uniprot.org/uniprotkb/E1BND0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESEEEQHMTTLLCMGFSDPATIRKALRLAKNDINEAVALLTNERPGLDYGGYEPMDSGGGPSPGPGGGSRGDGGGCDGPSRGGSTGGGGGFDPPPAYHEVVDAEKNDENGNCSGEGIEFPTTNLYELESRVLTDHWSIPYKREESLGKCLLASTYLARLGLSESDENCKRFMDRCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLIELVAERIKQDPIPTGLLAVLTMAFNPDNEYHFKNRMKVSQRNWAEVFGEGNMFAVSPVSTFQKEPHGWVVDLVNKFGELGGFAAIQAKLHSEDIELGAVSALVQPLGVCAEYLNSSVVQPMLDPVILNTIQDVRSVEEKDLKDKRLVSIPELLSAIKLLCMRFQPDLVTVVDDLRLDILLRMLKSPHFSAKMNSLKEVTKLIEDSTLSKSVKNAIDTDRLLDWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELTKIWKIQSGQSSTVIENIHTIIAAAAVKFNSDQLNHLFVLIQKSWETESDRVRQKLLSLIGRIGREARFETTSGKVLDVLWELAHLPTLPSSLIQQALEEHLTILSDAYAVKEAIKRSYIIKCIEDIKRPGEWSGLDKNKKDGFKSSQINNPQFVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLVTGSLIACHRLAAAVAGPGGLTGSTLVDGRYTYREYLEAHLKFLAFFLQEATLYLGWNRAKEIWECLVTGQDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLESYEITMNGFNLFKTFFENVNLCDHRLKRQGAQLYVEKLELIGMDFIWKIAMESPDEEIANEAIQLIINYSYINLNPRLKKDSVSLHKKFIADCYTRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPYRSTKLVIIERLLLLAERYVITIEDFYSVPRTILPHGASFHGHLLTLNVTYESTKDTFTVEAHSNETIGSVRWKIAKQLCSPVDSIQIFTNDSLLTVNKDQKLLHQLGFSDEQILTVKTSGSGTPSGSSADSSTSSSSSSSGVFSSSYAMEQEKSLPGVVMALVCNVFDMLYQLANLEEPRITLRVRKLLLLIPTDPAIQEALDQLDSLGRKKTLLSETSSQSSKSPSLSSKQQHQPSASSILESLFRSFAPGMSTFRVLYNLEVLSSKLMPTADDDMARNCAKSFCENFLKAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQTLPTLLDEDLTKDGIEALSSRPFRNVSRQTSRQMSLCGTPEKSSYRQLSVSDRSSIRVEEIIPAARVAIQTMEVGDFTSTVACFMRLSWAAAAGRLDLVGSSQPIKESNSLFPAGIRNRLSSSGSNCSSGSEGDPVALHAGICVRQQSVSTKDSLIAGEALSLLVTCLQLRSQQLASFYNLPCVADFIIDILLGSPSAEIRRVACDQLYTLSQTDTSAHPDVQKPNQFLLGVILTAQLPLWSPTSIMRGVNQRLLSQCMEYFDLRCQLLDDLTTSEMEQLRISPATMLEDEITWLENFEPNRTAECETSEADNILLAGHLRLIKTLLSLCGAEKEMLGSSLIKPLLDDFLFRASRIILNSHSPAGSAAISQQDFHPKCSTVNSRLAAYEVLVMLADSSPSNLQIITKELLSMHHQPDPALTKEFDYLPPVDSRSSSGFVGLRNGGATCYMNAVFQQLYMQPGLPESLLSVDDDTDNPDDSVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKMGRDQIFKNTFQGIYSDQKICKDCPHRYEREETFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRTTVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVSGMARQDSSSEVGENGRSTDQGGGGSPRKKVALTENYELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVIEEFDLNDETLEYECFGGEYRPKVYDQTNPYTDVRRRYWNAYMLFYQRVSDQNSPVLPKKSRVSVVRQEAEDLSLSAPSSPEISPQSSPRPHRPNNDRLSILTKLVKKGEKKGLFVEKMPVRIYQMVRDENLKFMKNRDVYSSDYFSFVLSLASLNATKLKHPYYPCMAKVSLQLAIQFLFQTYLRTKKKLRVDTEEWIATIEALLSKSFDACQWLVEYFISSEGRELIKIFLLECNVREVRVAVATILEKTLDSALFYQDKLKSLHQLLEVLLALLDKDVPENCKNCAQYFFLFNTFVQKQGIKAGDLLLKHSALRHMISFLLGASRQSTQIRRWSSAQAREFGNLHNTVALLVLHSDVSSQRNVAPGVFKQRPPISIAPSSPLLPLHEEVEALLFLSEGKPYLLEVMFALRELTGSLLALIEMVVYCCFCNEHFSFTMLHFIKNQLETAPPHELKNTFQLLHEILVIEDPIQVERVKFVFETENGLLALMHHSNHVDSSRCYQCVKFLVTLAQKCPAAKEYFKENSHHWSWAVQWLQKKMSEHYWTPQSNVSNETSTGKTFQRTISAQDTLAYATALLNEKEQSGSSNGSESSPANENGERHLQQGSESPMMIGELRSDLDDVDP", "length": 2617, "header": "tr|E1BND0-1|E1BND0_BOVIN Isoform 1 of Ubiquitin carboxyl-terminal hydrolase 24 OS=Bos taurus OX=9913 GN=USP24 PE=3 SV=1 CANONICAL=E1BND0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LYF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYF8/entry", "sequence": { "sequence": "MKEMGLGSRPAHSKSIALSPYQLPAFQMKKGQDTVKGWRKESVINKKNDENGNCSGEGIEFPTTNLYELESRVLTDHWSIPYKREESLGKCLLASTYLARLGLSESDENCKRFMDRCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLIELVAERIKQDPIPTGLLAVLTMAFNPDNEYHFKNRMKVSQRNWAEVFGEGNMFAVSPVSTFQKEPHGWVVDLVNKFGELGGFAAIQAKLHSEDIELGAVSALVQPLGVCAEYLNSSVVQPMLDPVILNTIQDVRSVEEKDLKDKRLVSIPELLSAIKLLCMRFQPDLVTVVDDLRLDILLRMLKSPHFSAKMNSLKEVTKLIEDSTLSKSVKNAIDTDRLLDWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELTKIWKIQSGQSSTVIENIHTIIAAAAVKFNSDQLNHLFVLIQKSWETESDRVRQKLLSLIGRIGREARFETTSGKVLDVLWELAHLPTLPSSLIQQALEEHLTILSDAYAVKEAIKRSYIIKCIEDIKRPGEWSGLDKNKKDGFKSSQINNPQFVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLVTGSLIACHRLAAAVAGPGGLTGSTLVDGRYTYREYLEAHLKFLAFFLQEATLYLGWNRAKEIWECLVTGQDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLESYEITMNGFNLFKTFFENVNLCDHRLKRQGAQLYVEKLELIGMDFIWKIAMESPDEEIANEAIQLIINYSYINLNPRLKKDSVSLHKKFIADCYTRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPYRSTKLVIIERLLLLAERYVITIEDFYSVPRTILPHGASFHGHLLTLNVTYESTKDTFTVEAHSNETIGSVRWKIAKQLCSPVDSIQIFTNDSLLTVNKDQKLLHQLGFSDEQILTVKTSGSGTPSGSSADSSTSSSSSSSGVFSSSYAMEQEKSLPGVVMALVCNVFDMLYQLANLEEPRITLRVRKLLLLIPTDPAIQEALDQLDSLGRKKTLLSETSSQSSKSPSLSSKQQHQPSASSILESLFRSFAPGMSTFRVLYNLEVLSSKLMPTADDDMARNCAKSFCENFLKAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQTLPTLLDEDLTKDGIEALSSRPFRNVSRQTSRQMSLCGTPEKSSYRQLSVSDRSSIRVEEIIPAARVAIQTMEVGDFTSTVACFMRLSWAAAAGRLDLVGSSQPIKESNSLFPAGIRNRLSSSGSNCSSGSEGDPVALHAGICVRQQSVSTKDSLIAGEALSLLVTCLQLRSQQLASFYNLPCVADFIIDILLGSPSAEIRRVACDQLYTLSQTDTSAHPDVQKPNQFLLGVILTAQLPLWSPTSIMRGVNQRLLSQCMEYFDLRCQLLDDLTTSEMEQLRISPATMLEDEITWLENFEPNRTAECETSEADNILLAGHLRLIKTLLSLCGAEKEMLGSSLIKPLLDDFLFRASRIILNSHSPAGSAAISQQDFHPKCSTVNSRLAAYEVLVMLADSSPSNLQIITKELLSMHHQPDPALTKEFDYLPPVDSRSSSGFVGLRNGGATCYMNAVFQQLYMQPGLPESLLSVDDDTDNPDDSVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKMGRDQIFKNTFQGIYSDQKICKDCPHRYEREETFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRTTVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVSGMARQDSSSEVGENGRSTDQGGGGSPRKKVALTENYELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVIEEFDLNDETLEYECFGGEYRPKVYDQTNPYTDVRRRYWNAYMLFYQRVSDQNSPVLPKKSRVSVVRQEAEDLSLSAPSSPEISPQSSPRPHRPNNDRLSILTKLVKKGEKKGLFVEKMPVRIYQMVRDENLKFMKNRDVYSSDYFSFVLSLASLNATKLKHPYYPCMAKVSLQLAIQFLFQTYLRTKKKLRVDTEEWIATIEALLSKSFDACQWLVEYFISSEGRELIKIFLLECNVREVRVAVATILEKTLDSALFYQDKLKSLHQLLEVLLALLDKDVPENCKNCAQYFFLFNTFVQKQGIKAGDLLLKHSALRHMISFLLGASRQSTQIRRWSSAQAREFGNLHNTVALLVLHSDVSSQRNVAPGVFKQRPPISIAPSSPLLPLHEEVEALLFLSEGKPYLLEVMFALRELTGSLLALIEMVVYCCFCNEHFSFTMLHFIKNQLETAPPHELKNTFQLLHEILVIEDPIQVERVKFVFETENGLLALMHHSNHVDSSRCYQCVKFLVTLAQKCPAAKEYFKENSHHWSWAVQWLQKKMSEHYWTPQSNVSNETSTGKTFQRTISAQDTLAYATALLNEKEQSGSSNGSESSPANENGERHLQQGSESPMMIGELRSDLDDVDP", "length": 2558, "header": "tr|A0A3Q1LYF8-1|A0A3Q1LYF8_BOVIN Computationally mapped isoform of ubiquitinyl hydrolase 1 OS=Bos taurus OX=9913 GN=USP24 PE=3 SV=2 CANONICAL=E1BND0-1" }, "locus": { "chromosome": "3", "start_pos": 91284627, "end_pos": 91135462, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072152.3", "url": "https://www.ensembl.org/id/ENSBTAT00000072152.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062290.2", "url": "https://www.ensembl.org/id/ENSBTAP00000062290.2" } ] } }, { "isoform_ac": "A0A3Q1M1T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1T8/entry", "sequence": { "sequence": "MDRCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLIELVAERIKQDPIPTGLLAVLTMAFNPDNEYHFKNRMKVSQRNWAEVFGEGNMFAVSPVSTFQKEPHGWVVDLVNKFGELGGFAAIQAKLHSEDIELGAVSALVQPLGVCAEYLNSSVVQPMLDPVILNTIQDVRSVEEKDLKDKRLVSIPELLSAIKLLCMRFQPDLVTVVDDLRLDILLRMLKSPHFSAKMNSLKEVTKLIEDSTLSKSVKNAIDTDRLLDWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELTKIWKIQSGQSSTVIENIHTIIAAAAVKFNSDQLNHLFVLIQKSWETESDRVRQKLLSLIGRIGREARFETTSGKVLDVLWELAHLPTLPSSLIQQALEEHLTILSDAYAVKEAIKRSYIIKCIEDIKRPGEWSGLDKNKKDGFKQGGLTGNYVSLPGYTETKQRSSQINNPQFVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLVTGSLIACHRLAAAVAGPGGLTGSTLVDGRYTYREYLEAHLKFLAFFLQEATLYLGWNRAKEIWECLVTGQDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLESYEITMNGFNLFKTFFENVNLCDHRLKRQGAQLYVEKLELIGMDFIWKIAMESPDEEIANEAIQLIINYSYINLNPRLKKDSVSLHKKFIADCYTRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPYRSTKLVIIERLLLLAERYVITIEDFYSVPRTILPHGASFHGHLLTLNVTYESTKDTFTVEAHSNETIGSVRWKIAKQLCSPVDSIQIFTNDSLLTVNKDQKLLHQLGFSDEQILTVKTSGSGTPSGSSADSSTSSSSSSSGVFSSSYAMEQEKSLPGVVMALVCNVFDMLYQLANLEEPRITLRVRKLLLLIPTDPAIQEALDQLDSLGRKKTLLSETSSQSSKSPSLSSKQQHQPSASSILESLFRSFAPGMSTFRVLYNLEVLSSKLMPTADDDMARNCAKSFCENFLKAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQTLPTLLDEDLTKDGIEALSSRPFRNVSRQTSRQMSLCGTPEKSSYRQLSVSDRSSIRVEEIIPAARVAIQTMEVGDFTSTVACFMRLSWAAAAGRLDLVGSSQPIKESNSLFPAGIRNRLSSSGSNCSSGSEGDPVALHAGICVRQQSVSTKDSLIAGEALSLLVTCLQLRSQQLASFYNLPCVADFIIDILLGSPSAEIRRVACDQLYTLSQTDTSAHPDVQKPNQFLLGVILTAQLPLWSPTSIMRGVNQRLLSQCMEYFDLRCQLLDDLTTSEMEQLRISPATMLEDEITWLENFEPNRTAECETSEADNILLAGHLRLIKTLLSLCGAEKEMLGSSLIKPLLDDFLFRASRIILNSHSPAGSAAISQQDFHPKCSTVNSRLAAYEVLVMLADSSPSNLQIITKELLSMHHQPDPALTKEFDYLPPVDSRSSSGFVGLRNGGATCYMNAVFQQLYMQPGLPESLLSVDDDTDNPDDSVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKMGRDQIFKNTFQGIYSDQKICKDCPHRYEREETFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRTTVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVSGMARQDSSSEVGENGRSTDQGGGGSPRKKVALTENYELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVIEEFDLNDETLEYECFGGEYRPKVYDQTNPYTDVRRRYWNAYMLFYQRVSDQNSPVLPKKSRVSVVRQEAEDLSLSAPSSPEISPQSSPRPHRPNNDRLSILTKLVKKGEKKGLFVEKMPVRIYQMVRDENLKFMKNRDVYSSDYFSFVLSLASLNATKLKHPYYPCMAKVSLQLAIQFLFQTYLRTKKKLRVDTEEWIATIEALLSKSFDACQWLVEYFISSEGRELIKIFLLECNVREVRVAVATILEKTLDSALFYQDKLKSLHQLLEVLLALLDKDVPENCKNCAQYFFLFNTFVQKQGIKAGDLLLKHSALRHMISFLLGASRQSTQIRRWSSAQAREFGNLHNTVALLVLHSDVSSQRNVAPGVFKQRPPISIAPSSPLLPLHEEVEALLFLSEGKPYLLEVMFALRELTGSLLALIEMVVYCCFCNEHFSFTMLHFIKNQLETAPPHELKNTFQLLHEILVIEDPIQVERVKFVFETENGLLALMHHSNHVDSSRCYQCVKFLVTLAQKCPAAKEYFKENSHHWSWAVQWLQKKMSEHYWTPQSNVSNETSTGKTFQRTISAQDTLAYATALLNEKEQSGSSNGSESSPANENGERHLQQGSESPMMIGELRSDLDDVDP", "length": 2465, "header": "tr|A0A3Q1M1T8-1|A0A3Q1M1T8_BOVIN Computationally mapped isoform of ubiquitinyl hydrolase 1 OS=Bos taurus OX=9913 GN=USP24 PE=3 SV=2 CANONICAL=E1BND0-1" }, "locus": { "chromosome": "3", "start_pos": 91284627, "end_pos": 91171455, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069058.3", "url": "https://www.ensembl.org/id/ENSBTAT00000069058.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062031.2", "url": "https://www.ensembl.org/id/ENSBTAP00000062031.2" } ] } }, { "isoform_ac": "E1BND0-1", "url": "https://www.uniprot.org/uniprotkb/E1BND0/entry", "sequence": { "sequence": "MESEEEQHMTTLLCMGFSDPATIRKALRLAKNDINEAVALLTNERPGLDYGGYEPMDSGGGPSPGPGGGSRGDGGGCDGPSRGGSTGGGGGFDPPPAYHEVVDAEKNDENGNCSGEGIEFPTTNLYELESRVLTDHWSIPYKREESLGKCLLASTYLARLGLSESDENCKRFMDRCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLIELVAERIKQDPIPTGLLAVLTMAFNPDNEYHFKNRMKVSQRNWAEVFGEGNMFAVSPVSTFQKEPHGWVVDLVNKFGELGGFAAIQAKLHSEDIELGAVSALVQPLGVCAEYLNSSVVQPMLDPVILNTIQDVRSVEEKDLKDKRLVSIPELLSAIKLLCMRFQPDLVTVVDDLRLDILLRMLKSPHFSAKMNSLKEVTKLIEDSTLSKSVKNAIDTDRLLDWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELTKIWKIQSGQSSTVIENIHTIIAAAAVKFNSDQLNHLFVLIQKSWETESDRVRQKLLSLIGRIGREARFETTSGKVLDVLWELAHLPTLPSSLIQQALEEHLTILSDAYAVKEAIKRSYIIKCIEDIKRPGEWSGLDKNKKDGFKSSQINNPQFVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLVTGSLIACHRLAAAVAGPGGLTGSTLVDGRYTYREYLEAHLKFLAFFLQEATLYLGWNRAKEIWECLVTGQDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLESYEITMNGFNLFKTFFENVNLCDHRLKRQGAQLYVEKLELIGMDFIWKIAMESPDEEIANEAIQLIINYSYINLNPRLKKDSVSLHKKFIADCYTRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPYRSTKLVIIERLLLLAERYVITIEDFYSVPRTILPHGASFHGHLLTLNVTYESTKDTFTVEAHSNETIGSVRWKIAKQLCSPVDSIQIFTNDSLLTVNKDQKLLHQLGFSDEQILTVKTSGSGTPSGSSADSSTSSSSSSSGVFSSSYAMEQEKSLPGVVMALVCNVFDMLYQLANLEEPRITLRVRKLLLLIPTDPAIQEALDQLDSLGRKKTLLSETSSQSSKSPSLSSKQQHQPSASSILESLFRSFAPGMSTFRVLYNLEVLSSKLMPTADDDMARNCAKSFCENFLKAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQTLPTLLDEDLTKDGIEALSSRPFRNVSRQTSRQMSLCGTPEKSSYRQLSVSDRSSIRVEEIIPAARVAIQTMEVGDFTSTVACFMRLSWAAAAGRLDLVGSSQPIKESNSLFPAGIRNRLSSSGSNCSSGSEGDPVALHAGICVRQQSVSTKDSLIAGEALSLLVTCLQLRSQQLASFYNLPCVADFIIDILLGSPSAEIRRVACDQLYTLSQTDTSAHPDVQKPNQFLLGVILTAQLPLWSPTSIMRGVNQRLLSQCMEYFDLRCQLLDDLTTSEMEQLRISPATMLEDEITWLENFEPNRTAECETSEADNILLAGHLRLIKTLLSLCGAEKEMLGSSLIKPLLDDFLFRASRIILNSHSPAGSAAISQQDFHPKCSTVNSRLAAYEVLVMLADSSPSNLQIITKELLSMHHQPDPALTKEFDYLPPVDSRSSSGFVGLRNGGATCYMNAVFQQLYMQPGLPESLLSVDDDTDNPDDSVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKMGRDQIFKNTFQGIYSDQKICKDCPHRYEREETFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRTTVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVSGMARQDSSSEVGENGRSTDQGGGGSPRKKVALTENYELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVIEEFDLNDETLEYECFGGEYRPKVYDQTNPYTDVRRRYWNAYMLFYQRVSDQNSPVLPKKSRVSVVRQEAEDLSLSAPSSPEISPQSSPRPHRPNNDRLSILTKLVKKGEKKGLFVEKMPVRIYQMVRDENLKFMKNRDVYSSDYFSFVLSLASLNATKLKHPYYPCMAKVSLQLAIQFLFQTYLRTKKKLRVDTEEWIATIEALLSKSFDACQWLVEYFISSEGRELIKIFLLECNVREVRVAVATILEKTLDSALFYQDKLKSLHQLLEVLLALLDKDVPENCKNCAQYFFLFNTFVQKQGIKAGDLLLKHSALRHMISFLLGASRQSTQIRRWSSAQAREFGNLHNTVALLVLHSDVSSQRNVAPGVFKQRPPISIAPSSPLLPLHEEVEALLFLSEGKPYLLEVMFALRELTGSLLALIEMVVYCCFCNEHFSFTMLHFIKNQLETAPPHELKNTFQLLHEILVIEDPIQVERVKFVFETENGLLALMHHSNHVDSSRCYQCVKFLVTLAQKCPAAKEYFKENSHHWSWAVQWLQKKMSEHYWTPQSNVSNETSTGKTFQRTISAQDTLAYATALLNEKEQSGSSNGSESSPANENGERHLQQGSESPMMIGELRSDLDDVDP", "length": 2617, "header": "tr|E1BND0-1|E1BND0_BOVIN Isoform 1 of Ubiquitin carboxyl-terminal hydrolase 24 OS=Bos taurus OX=9913 GN=USP24 PE=3 SV=1 CANONICAL=E1BND0-1" }, "locus": { "chromosome": "3", "start_pos": 91284627, "end_pos": 91131528, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061043.5", "url": "https://www.ensembl.org/id/ENSBTAT00000061043.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053571.2", "url": "https://www.ensembl.org/id/ENSBTAP00000053571.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1036, "start_aa": "Thr", "end_pos": 1036, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1036", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 891, "start_aa": "Thr", "end_pos": 891, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr891", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:532257", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532257", "resource": "KEGG Pathway" }, { "id": "R-BTA-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZQ83-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 24", "gene_name": "USP24", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MESEEEQHMTTLLCMGFSDAAAIRKALRLAKNDINEAVALLTNERPGLHYGGYEPMESGQGPPPGHGSPAGGQGSRDGDGGGGGGSGGFDPPPAYHEVVETEKNDENGNCSGEGIEFPTTNLYELESRVLTDHWSIPYKREESLGKCLIASTYLARLGLSDSDENCKRFMDRCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLVDLVAERVKQDPIPVGLLGVLTMAFNPDNEYHFKNRMKVCQRNWAEVFGEGNMHAVSPISTFQKEPHGWLVDLVNRFAELGGFSAIQSKLNSEDIELGAISALVQPFGVCAEYLNSSVVQPMLDPVIHKMIKYVQNVEEKDLKDKRLVSIPELLSGIKLLCMRFQPDLVTAVDDLRLDILLRMLKSPHFSAKMNSLKEVTKLIEDSTVSKSVKNAIDTDRLLNWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELTKIWRIQSGQSSTVIENIHTIIAAAAVKFSSDQLNHLFVLIQKSWETESDRVRQKLLSLIGRIGREARVETTTGKVLEVLWELAHLPTLPCSLIQQALEEHLTILSDAYAVKEAIKRSYIIKCIEDIKRKMKPPRKAMSSSNNESSQHNNPQFVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLVTGSLISCHRLAASVAGPGGLVGATLVDGRYTYREYLEAHLKFLAFFLQEATLYLGWNRAKEIWECLVTGQDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLESYEITMNGFSLFKTFFENVNLCDHRLKRQGTQLSVEKLELIGMDFIWKIAMESPDEEIANEAIQLIINYSYINLTPRLKKDSVSLHKKFIADCYTRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPYRSTKLVIIERLLLLAERYVITIEDLYSVPRTILPHGASFHGHLLTLNVTYESTKDTFTIEAHSNETVGSIRWKIAKMLNSPVDNIQIFANDSLLTVNKDQKLLHQLGFSDEQVLTVKTSGSGTPSGSSADSSTSSSNSSSVFSSSYAMEQEKSLPGVVMALVCNVFDMLYQLANLEEPRITLRVRKLLLLIPTDPAIQEALDQLDSLGRKKTLLSESSSQSSKSPSLSSKHQHQPSASSILESLFRSFAPGMSTFRVLYNLEVLSSKLMPTADDEMARNCAKSFCENFLRAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQTMPTLLDEDFIKDGVEALSSRPFRNVSRQASRQMSICGTPEKSSYRQLSVSDRSSIRVEEIIPAARVAIQTMEVNDFTSTVACFMRLSWAAAAGRLDLVGSSQPIKENNTLFPAGIRNRLSSSGSNCSSGSEGEPTALHAGICVRQQSVSTKDALIAGEALSLLVTCLQLRSQQLGSFYNLPCVADFIIDILLGSPSAEIRRVACDQLYTLSQTDTSTHPDVQKPNQFLLSVILGAQLPLWSPTSIMRGINQRLLSQCTEYFDLRCQLLDDLTSSEMEQLKISPAAMLEDEITWLENFEPNRTAECETSEADNILLAGHLRLIKTLLSLCGAEKEMVGSSLIKPLLDDFLFRASRIILNSHSPSGSAAISQQDFHPKCSTADSRLAAYEVLVMLADSSPSNLQLITKELLSMHHQCDPALTKEFDYLPPVDSRSISGFVGLKNGGATCYMNAVFQQLYMQPGLPEALLSIDDDTDNPDDNVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKIGRDQIFKNTFQGIFSDQKICKDCPHRYEREEAFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRTTVKRTCIKVLPNLLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVSGMARQDSSSEVGDNGRNVDQGGGGSPRKKVAPTENYELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVVEEFELTDETLEYECFGGEYRPKVYDQSNPYPDVRRRYWNAYMLFYQRVSDQNSPVLPKKSRVSVVRQEAEDLSLSAPSSPEISPQSSPRPHRPNSDRLSILTKLVRKGEKKGLFVEKMPVRIYQMVRDENLKFMKNRDVYSSDYFSFVLSLASLNATKVKHPYYPCMAKVSLQLAVQFLFQTYLRTKKKLRADTEEWIATIDALLSKSIDACQWLVEYFVGPEGRELVKTFLLECSVREVRVAVATILEKTLDSALFYQEKLKSLHQLLEVLLALLDKDVPENCKNCAQYFLLFNNFVQKQGIRASSLLLRHSALRHMINFLLGPNRQSNQNRRWSSAQAREFGYLHNTVALLVLHSDVSSQRNVAPGLFKQRPPLSITTSGPLLTLHEEVEALLFLSEGKPYLIEVMYALRELTGSLSVLIEMVVYCCFCNEHFSFTVLHFIKTQLETAPPHELKNIFQLLHEILVIEDPLQVERIKFAFETENGLIALMHHSNHVDSSRCYQCVKFLVTLAQKCPTAKDYFKENSHHWSWAVQWLQKKMSEHYWAPQSNVSNETSTAKTFQRTISAQDTLAYATALLNEKDQSGSSNGSESSPANENGDRHLQQGSESPMMIGETKNDLDDVDP", "length": 2612 }, "evidence": [ { "id": "E1BND0", "url": "https://omabrowser.org/oma/group/E1BND0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "B1AY13-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 24", "gene_name": "Usp24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESEEEQHMTTLLCMGFSDPATIRKALRLAKNDINEAVALLTNERPGLDYGGYEPMDSGGPSPGPGGGPRGDSGSDGSGPSRGGSTGGGGGFDPPPAYHEVVDAEKNDENGNCSGEGIEFPTTNLYELESRVLTDHWSIPYKREESLGKCLLASTYLARLGLSESDENCKRFMERCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLIELVAERMKQDPIPIGLLGVLTMAFNPDNEYHFKNRMKVSQRNWAEVFGEGNMFAISPVSTFQKEPHGWVVDLVNKFGELGGFAAIQAKLHSEDIELGAVSALVQPLGVCAEYLNSSVVQPMLDPVILTTIQDVRSVEEKDLKDKRLVSIPELLSAIKLLCMRFQPALVTTVDALRLDILLRMLKSPHFSAKMNSLKEVTKLIEDSTLSKSVKNAIDTDRLLDWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELTKIWKIQSGQSSTVIENIHTIIAAAAVKFNADQLNHLFVLIQKSWETESDRVRQKLLSLIGRIGREARFEATSGKVLDVLWELAHLPTLPSSLIQQALEEHLTILSDAYAVKEAVKRSYIIKCIEDIKRPGEWSSLEKNKKDGFKSSQLNNPQFVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLVTGSLLACHRLAAAVAGPGGLTGLTLVDGRYTYREYLEAHLKFLAFFLQEATLYLGWNRAKEIWECLVTGQDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLESYEITMNGFNLFKTFFENVNLCDHRLKRQGAQLYVEKLELVGMDFIWKIAMESPDEEIANEAIQLIINYSYINLNPRLKKDSVSLHKKFIADCYTRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPYRSTKLVIIERLLLLAERYVITIEDFYSVPRTILPHGASFHGHLLTLNVTYESTKDTFTVEAHSNETIGSVRWKIAKQLCSPVDNIQIFTNDSLLTVNKDQKLLHQLGFSDEQVLTVKTSGSGTPSGSSADSSTSSSSSSSGAFSSSYAMEQEKSLPGVVMALVCNVFDMLYQLANLEEPRITLRVRKLLLLIPTDPAIQEALDQLDSLGRKKTLLSETSSQSSKSPSLSSKQQHQPSASSILESLFRSFAPGMSTFRVLYNLEVLSSKLMPTADDDMARSCAKSFCENFLKAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQTMPTSLDEDLTKDGIEALSSRPFRNVSRQTSRQMSLCGTPEKSSYRQLSVSDRSSIRVEEIIPAARVAIQTMEASDFTATVACFMRLSWAAAAGRLDLVGSSQPIKESNSLFPAGIRSRLSSSGSNCSSSSEGEPAALHAGICVRQQSVSTKDALIAGEALSLLVTCLQLRSQQLASFYSLPCVADFIIDILLGSPSAEIRRVACDQLYTLSQTDTSAHPEVQKPNQFLLGVILTAQLPLWSPTSIMRGVNQRLLSQCMEYFDLRCQLLDDLTTSEMDQLRISPATMLEDEITWLDNFEPNRTADCETSEADNILLAGHLRLIKTLLSLCGAEKEMLGSSLIKPLLDDFLFRASRIIVNSHSPASSAAISQQDFHPKCSTVNSRLAAYEVLVMLADSSPSNLQIITKELLSMHHQPDPALTKEFDYLPPVDSRSSSGFVGLRNGGATCYMNAVFQQLYMQPGLPESLLSVDDDTDNPDDSVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKMGREQIFKNTFQGIYSDQKICKDCPHRYEREEAFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRITVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVAGMARQDSSSEVGENGRNMDQGGGGSPRKKVALTENYELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVIEEFDLNDETLEYECFGGEYRPKVYDQTNPYTDVRRRYWNAYMLFYQRVSDQNSPVLPKKSRVSVVRQEAEDLSLSAPSSPEISPQSSPRPHRPNNDRLSILTKLVKKGEKKGLFVEKMPARIYQMVRDENLKFMKNRDVYSSDYFSFVLSLASLNATKLKHPYYPCMAKVSLQLAIQFLFQTYLRTKKKLRVDTEEWIATIEALLSKSLDACQWLVEYFISSEGRELVKVFLLECSVREVRVAVATILEKTLDSALFYQDKLKSLHQLLEVLLALLDKDVPENCKNCAQYFSLFNTFVQKQGIRAGDLLLRHSALRHMISFLLGVSRQNSQIRRWSSAQAREFGNLHNTVALLVLHSDVSSQRNVAPGIFKQRPPISVAPSSPLLPLHEEVEALLFLSEGKPYLLEVMFALRELTGSLLALMEMVVYCCFCNEHFSFTMLHFIKNQLETAPPHELKNTFQLLHEVLVIEDPIQVERVKFVFETENGLLALMHHSNHVDSSRCYQCVKFLVTLAQKCPAAKEYFKENSHHWSWAVQWLQKKMSEHYWTPQSNVSNETSTGKTFQRTISAQDTLAYATALLNEKEQSGSSNGSESSPANENGERHLQQGSESPMMIGELRSDLDDVDP", "length": 2617 }, "evidence": [ { "id": "E1BND0", "url": "https://omabrowser.org/oma/group/E1BND0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LSM0-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 24", "gene_name": "Usp24", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESEEEQHMTTLLCMGFSDPATIRKALRLAKNDINEAVALLTNERPGLDYGGYEPMDSGGPSPGLGGGPRGDGGGEGSGPSRGGSTGGGGGFDPPPAYHEVVDAEKNDENGNCSGEGVEFPTTNLYELESRVLTDHWSIPYKREESLGKCLLASTYLARLGLSESDENCKRFMERCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLIELVAERMKQDPIPIGLLGVLTMAFNPDNEYHFKNRMKVSQRNWAEVFGEGNMFAVSPVSTFQKEPHGWVVDLVNKFGELGGFAAIQAKLHSEDIELGAVSALVQPLGVCAEYLNSSVVQPMLDPVILTTIQDVRSVEEKDLKDKRLVSIPELLSAIKLLCMRFQPDLVTIVDDLRLDILLRMLKSPHFSAKMNSLKEVTKLIEDSTLSKSVKNAIDTDRLLDWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELTKIWKIQSGQSSTVIENIHTIIAAAAVKFNADQLNHLFVLIQKSWETETDRVRQKLLSLIGRIGREARFEATSGKVLDVLWELAHLPTLPSSLIQQALEEHLTILSDAYAVKEAVKRSYIIKCIEDIKRPGEWSGLEKNKKDGFKSSQHNNPQFVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLVTGSLLACHRLAAAVAGPGGLTGLTLVDGRYTYREYLEAHLKFLAFFLQEATLYLGWNRAKEIWECLVTGQDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLESYEITMNGFNLFKTFFENVNLCDHRLKRQGAQLYVEKLELVGMDFIWKIAMESPDEEIANEAIQLIINYSYINLNPRLKKDSVSLHKKFIADCYTRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPYRSTKLVIIERLLLLAERYVITIEDFYSVPRTILPHGASFHGHLLTLNVTYESTKDTFTVEAHSNETIGSVRWKIAKQLCSPVDNIQIFTNDSLLTVNKDQKLLHQLGFSDEQVLTVKTSGSGTPSGSSADSSTSSSSSSSGVFSSSYAMEQEKSLPGVVMALVCNVFDMLYQLANLEEPRITLRVRKLLLLIPTDPAIQEALDQLDSLGRKKTLLSETSSPSSKSPSLSSKQQQQPSASSILESLFRSFAPGMSTFRVLYNLEVLSSKLMPTADDDMARSCAKSFCENFLKAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQTMPTSLDEDLTKDGIEALSSRPFRNVSRQTSRQMSLCGTPEKSSYRQLSVSDRSSIRVEEIIPAARVAIQTMEANDFTATVACFMRLSWAAAAGRLDLVGSSQPIKESNSLFPAGIRNRLSSSGSNCSSSSEGEPAALHAGICVRQQSVSTKDALIAGEALSLLVTCLQLRSQQLASFYSLPCVADFIIDILLGSPSAEIRRVACDQLYTLSQTDTSAHPEVQKPNQFLLGVILTAQLPLWSPTSIMRGVNQRLLSQCMEYFDLRCQLLDDLTTSEMEQLRVSPAAMLEDEVTWLDNFEPNRTAECETSEADNILLAGHLRLIKTLLSLCGAEKEVLGSSLIKPLLDDFLFRASRIILNSHSPAGSAAISQQDFHPKCSTVNSRLAAYEVLVMLADSSPSNLQIITKELLSMHHQPDPALTKEFDYLPPVDSRSISGFVGLRNGGATCYMNAVFQQLYMQPGLPESLLSVDDDTDNPDDSVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKMGREQIFKNTFQGIYSDQKICKDCPHRYEREEAFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRITVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVAGMARQDSSSEVGENGRNMDQGGGGSPRKKVALTENYELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVIEEFDLNDETLEYECFGGEYRPKVYDQTNPYPDVRRRYWNAYMLFYQRVSDQNSPVLPKKSRVSVVRQEAEDLSLSAPSSPEISPQSSPRPHRPNNDRLSILTKLVKKGEKKGLFVEKMPARIYQMVRDENLKFMKNRDVYSSDYFSFVLSLASLNATKLKHPHYPCMAKVSLQLAVQFLFQTYLRTKKKLRVDTEEWIATIEALLSKSLDACQWLVEYFISSEGRELVKVFLLECSVREVRVAVATILEKTLDSALFYQDKLKSLHQLLEVLLALLDKDVPENCKNCAQYFSLFNTFVQKQGIRAGDLLLRHSALRHMISFLLGVSQQNSQIRRWSSAQAREFGNLHNTVALLVLHTDVSSQRNVAPGIFKQRPPISVAPSSPLLPLHEEVEALLFLSEGKPYLLEVMFALRELTGSLLALMEMVVYCCFCNEHFSFTMLHFIKNQLETAPPHELKNTFQLLHEILVMEDPIQVERVKFVFETENGLLALMHHSNHVDSSRCYQCVKFLVTLAQKCPAAKEYFKENSHHWSWAVQWLQKKMSEHYWTPQSNVSNETSTGKTFQRTISAQDTLAYATALLNEKEQSGSSNGSESSPANENGERRLQQGSESPMMIGELRSDLDDVDP", "length": 2617 }, "evidence": [ { "id": "E1BND0", "url": "https://omabrowser.org/oma/group/E1BND0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1Q6K1-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 24", "gene_name": "usp24", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMETEEEQHMTTLLCMGFPDPVAIRKALRLAKNDINEAVALLTNESPGLGYGYEPMESGPSPGSGDGENSGRTVTGGFDPPPAYHDVVESERSNDENGNCSGNSMEFPTTNLYELESRVFTDHWSIPYKREESLGKCLIASTCLARHGLADADENCKRFIDRCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLVDLVAERVKQDPIPIGLMGVLTMAFNPDNEYHFKNRMKACQRNWAEVFGEDSMFAVSPSSSYQKEPHGWLVDLVNRFGEMGGFTAIQCKLNQEEIEIGCVSALVQPLGVCAEYLNSSLVQPMLDPVIHKMITYVQNLEEKDLKDKRLVSIPELLSAIKLLCMRFQRELVNVVDDLRLDILLRMLKTPHFSAKMNSLKEVTKLIEESTVSKTVKNAIDTDRLLDWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELSKIWKIQAGQSSTVIENIHTIIAAAAVKFNFDQLSHLFVLIQKSWEVESDRVRQKLLSLIGRIGREARSEATTGKVLEVLWELAHLPTLPTSLVQQALEEHLTILSDAYAVKETIKRNYIIKCIEDIKKMQIQEDSKSPSETQVSFLTGTWGKKKPSSLAKSSQQTNPQTVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLITGSLVSCHRLAVSVAGSNGLSGSTLVDGRYSYQEYLEGHLKFLAFFLQEASLYLVWNRAKEIWECLVSGMDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLEPYEITMNGFNLFKTFFENVNLSDHRLKRQGTQLCVERLDLAGMDFIWRIAMESPDEDIANEAIQLIITYSYINLNPKMKKDSVSLHKKFIADCYKRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPSRSSKLVIIERLLLLAERYVITIEDLYSVPRTILPHGASFHGHPVTLHITYESTKDTFTLEAHSNETIGSIRWKIADQLSCPVDNVQIFANDSMLTMNRDQKLLNQLGFSDEQSLTVKSSGTGTPSGSSADSSASASSSSSGVFNSAYALEQEKSLPGVVMALVCNVFEMLYQLANLEEPRITLRVRKLLLLIPTDPEVQDALDNFVPKESSVWSHQKTLFTLGSGSQASKSPSLSSKQQHQQSAASILESLFRSSAPGMSTFRVLYNLEVLSSKLMPTSDDEMAKTSVKSFCENFLKAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQAMPSILDEELSKDDTLSSRPFRNAGRQSGRQLSVCGTPEKSSYRQVSVSDRSSIRVEEIIPAARVAIQTMEVGDFTSTVACFMRLTWAAAAGRLDLVGSSQPIRETTNSLLPLGVRSRVSSTGSNCSSSSEGEVTTLQAGICVKQLFVSIKDTIIAREALSLLVTCLQLRSQQLCSFYSLLSVNDFIIDILLGSPSGEIRRVACDQLYTLSQSDTSAYPDLQKPNLFLLKVVLTAQLPLWSPTSIMRGVNQRLLSQCTEYFDLRCQLLDDLTTSEMEQLQIGPAAMLEDEISWLDNFEPTWTTELETSEADNILLAGHLRLIKTLLSLCGTEKEQFGPSLIQQLLDDFLFRASRIILNSDSSSSTTASIHDFHPKCSTVSSRLAAYEVLVMLADSSLTNLQLITKELLSMHHQSDPSLSKEFDYLPPVDSRSISGFVGLKNGGATCYMNAVFQQLYMQPGLPEGVLSIEDDTENPEESVFCQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLVDQLDEHLKKIGREQIFKNTFQGIFSDQKICKDCPHRYEREETFMALNLGVTSCQSLEISLDQFVRGEVLDGSNAYYCEKCKEKRTTVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWVLNMEPYTVSGMARQDSSADHGENGRGGEAGSGGSPRKKVTISENYELVGVVVHSGQAHAGHYYSFIKDRRGSARGRWYKFNDNVVEEFDMNDETLEYECFGGEYRPKVYDQSNPYPDVRRRYWNAYMLFYQRISDQNSPVLPKKSRVSIMRQEAEDLSLSAPSSPEISPQSSPRPPRANNDRLTLLTRLVKKGEKKGLFVEKMPARIFQMVRDENLKFMKNRDVYNSDYFSFTLSLASVNATKLKHASYQAMAKTSLQLAVQFLLHTYLRTKKKLRVDTEEWIATVEVLLSKSSEACQWMVQYLVAPEGREIIKICLLECSVREVRVVVATILEKTLESALYFQDAGLDCLLDMLLSLLDKDVPDNCKNCSQYFSLFSNFAQRGCGPCQLLLKHSAYRRMLVFLLGPNRQNNQHRRWSSAQAREFLHLHNTLALMVLHTDLTSQRTEAQGVFKQASSGLVAPSSVLMPLHPDINTLLFKADGQAYLMEVMFAMRELSGPLSFLIEMITYSSFCNEPFSLGVLQLLKNHLETAPPHELKNVFQMLLEILMLEDPLQSQRLKFAFESEKGLLALMHQSNNVDSSRCYQCVKFLVTLAQKCSPAKDYFKELSGHWSWAVQWLQKKMSEHYWTPQSNVSNETSTAKTFQRTISAQDTLAYATALLNEKDQSGSSNGSDGSPANENSDRSLRQGSESPMMLGDSRSDLEDVDP", "length": 2621 }, "evidence": [ { "id": "E1BND0", "url": "https://omabrowser.org/oma/group/E1BND0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9UPU5-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 24", "gene_name": "USP24", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESEEEQHMTTLLCMGFSDPATIRKALRLAKNDINEAVALLTNERPGLDYGGYEPMDSGGGPSPGPGGGPRGDGGGDGGGGGPSRGGSTGGGGGFDPPPAYHEVVDAEKNDENGNCSGEGIEFPTTNLYELESRVLTDHWSIPYKREESLGKCLLASTYLARLGLSESDENCRRFMDRCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLIELVAERIKQDPIPTGLLGVLTMAFNPDNEYHFKNRMKVSQRNWAEVFGEGNMFAVSPVSTFQKEPHGWVVDLVNKFGELGGFAAIQAKLHSEDIELGAVSALIQPLGVCAEYLNSSVVQPMLDPVILTTIQDVRSVEEKDLKDKRLVSIPELLSAVKLLCMRFQPDLVTIVDDLRLDILLRMLKSPHFSAKMNSLKEVTKLIEDSTLSKSVKNAIDTDRLLDWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELTKIWKIQSGQSSTVIENIHTIIAAAAVKFNSDQLNHLFVLIQKSWETESDRVRQKLLSLIGRIGREARFETTSGKVLDVLWELAHLPTLPSSLIQQALEEHLTILSDAYAVKEAIKRSYIIKCIEDIKRPGEWSGLEKNKKDGFKSSQLNNPQFVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLVTGSLIACHRLAAAVAGPGGLSGSTLVDGRYTYREYLEAHLKFLAFFLQEATLYLGWNRAKEIWECLVTGQDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLESYEITMNGFNLFKTFFENVNLCDHRLKRQGAQLYVEKLELIGMDFIWKIAMESPDEEIANEAIQLIINYSYINLNPRLKKDSVSLHKKFIADCYTRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPYRSTKLVIIERLLLLAERYVITIEDFYSVPRTILPHGASFHGHLLTLNVTYESTKDTFTVEAHSNETIGSVRWKIAKQLCSPVDNIQIFTNDSLLTVNKDQKLLHQLGFSDEQILTVKTSGSGTPSGSSADSSTSSSSSSSGVFSSSYAMEQEKSLPGVVMALVCNVFDMLYQLANLEEPRITLRVRKLLLLIPTDPAIQEALDQLDSLGRKKTLLSESSSQSSKSPSLSSKQQHQPSASSILESLFRSFAPGMSTFRVLYNLEVLSSKLMPTADDDMARSCAKSFCENFLKAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQTMPTLLDEDLTKDGIEALSSRPFRNVSRQTSRQMSLCGTPEKSSYRQLSVSDRSSIRVEEIIPAARVAIQTMEVSDFTSTVACFMRLSWAAAAGRLDLVGSSQPIKESNSLCPAGIRNRLSSSGSNCSSGSEGEPVALHAGICVRQQSVSTKDSLIAGEALSLLVTCLQLRSQQLASFYNLPCVADFIIDILLGSPSAEIRRVACDQLYTLSQTDTSAHPDVQKPNQFLLGVILTAQLPLWSPTSIMRGVNQRLLSQCMEYFDLRCQLLDDLTTSEMEQLRISPATMLEDEITWLDNFEPNRTAECETSEADNILLAGHLRLIKTLLSLCGAEKEMLGSSLIKPLLDDFLFRASRIILNSHSPAGSAAISQQDFHPKCSTANSRLAAYEVLVMLADSSPSNLQIIIKELLSMHHQPDPALTKEFDYLPPVDSRSSSGFVGLRNGGATCYMNAVFQQLYMQPGLPESLLSVDDDTDNPDDSVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKMGRDQIFKNTFQGIYSDQKICKDCPHRYEREEAFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRITVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVSGMARQDSSSEVGENGRSVDQGGGGSPRKKVALTENYELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVIEEFDLNDETLEYECFGGEYRPKVYDQTNPYTDVRRRYWNAYMLFYQRVSDQNSPVLPKKSRVSVVRQEAEDLSLSAPSSPEISPQSSPRPHRPNNDRLSILTKLVKKGEKKGLFVEKMPARIYQMVRDENLKFMKNRDVYSSDYFSFVLSLASLNATKLKHPYYPCMAKVSLQLAIQFLFQTYLRTKKKLRVDTEEWIATIEALLSKSFDACQWLVEYFISSEGRELIKIFLLECNVREVRVAVATILEKTLDSALFYQDKLKSLHQLLEVLLALLDKDVPENCKNCAQYFFLFNTFVQKQGIRAGDLLLRHSALRHMISFLLGASRQNNQIRRWSSAQAREFGNLHNTVALLVLHSDVSSQRNVAPGIFKQRPPISIAPSSPLLPLHEEVEALLFMSEGKPYLLEVMFALRELTGSLLALIEMVVYCCFCNEHFSFTMLHFIKNQLETAPPHELKNTFQLLHEILVIEDPIQVERVKFVFETENGLLALMHHSNHVDSSRCYQCVKFLVTLAQKCPAAKEYFKENSHHWSWAVQWLQKKMSEHYWTPQSNVSNETSTGKTFQRTISAQDTLAYATALLNEKEQSGSSNGSESSPANENGDRHLQQGSESPMMIGELRSDLDDVDP", "length": 2620 }, "evidence": [ { "id": "E1BND0", "url": "https://omabrowser.org/oma/group/E1BND0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BND0", "url": "https://www.uniprot.org/uniprotkb/E1BND0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BND0", "url": "https://www.uniprot.org/uniprotkb/E1BND0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BND0", "url": "https://www.uniprot.org/uniprotkb/E1BND0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "E1BND0", "url": "https://www.uniprot.org/uniprotkb/E1BND0" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "E1BND0", "url": "https://www.uniprot.org/uniprotkb/E1BND0" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "E1BND0", "url": "https://www.uniprot.org/uniprotkb/E1BND0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "E1BND0", "url": "https://www.uniprot.org/uniprotkb/E1BND0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1003, "end_pos": 1005, "annotation": "n_glycosylation_sequon" }, { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1272, "end_pos": 1274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1373, "end_pos": 1375, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1548, "end_pos": 1550, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1987, "end_pos": 1989, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2146, "end_pos": 2148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2542, "end_pos": 2544, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2545, "end_pos": 2547, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2580, "end_pos": 2582, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 845, "end_pos": 847, "annotation": "n_glycosylation_sequon" }, { "start_pos": 960, "end_pos": 962, "annotation": "n_glycosylation_sequon" }, { "start_pos": 977, "end_pos": 979, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-5689973", "name": "USP10,USP24,USP42 deubiquitinate TP53", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BND0-1", "E1B9W9-1" ], "evidence": [ { "id": "R-BTA-5689973", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5689973" } ] }, { "id": "R-BTA-5696997", "name": "USP24 deubiquitinates DDB2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp