[ { "uniprot_canonical_ac": "P22105-3", "uniprot_ac": "P22105", "uniprot_id": "TENX_HUMAN", "mass": { "chemical_mass": 458388.0, "monoisotopic_mass": 458388.0 }, "refseq": { "ac": "NP_061978", "name": "tenascin-X isoform 1 precursor", "summary": "This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_061978" }, "gene_names": [ { "name": "TNXB", "type": "recommended", "evidence": [ { "id": "P22105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22105" } ] }, { "name": "EDS3", "type": "synonym", "evidence": [ { "id": "NP_061978", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_061978" } ] }, { "name": "EDSCLL1", "type": "synonym", "evidence": [ { "id": "NP_061978", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_061978" } ] }, { "name": "EDSCLL", "type": "synonym", "evidence": [ { "id": "NP_061978", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_061978" } ] }, { "name": "HXBL", "type": "synonym", "evidence": [ { "id": "NP_061978", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_061978" }, { "id": "P22105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22105" } ] }, { "name": "TENX", "type": "synonym", "evidence": [ { "id": "NP_061978", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_061978" } ] }, { "name": "TN-X", "type": "synonym", "evidence": [ { "id": "NP_061978", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_061978" } ] }, { "name": "TNXB1", "type": "synonym", "evidence": [ { "id": "NP_061978", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_061978" }, { "id": "P22105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22105" } ] }, { "name": "TNXB2", "type": "synonym", "evidence": [ { "id": "NP_061978", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_061978" }, { "id": "P22105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22105" } ] }, { "name": "TNXBS", "type": "synonym", "evidence": [ { "id": "NP_061978", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_061978" } ] }, { "name": "TNXB", "type": "synonym", "evidence": [ { "id": "NP_061978", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_061978" } ] }, { "name": "TNX", "type": "synonym", "evidence": [ { "id": "NP_061978", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_061978" }, { "id": "P22105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22105" } ] }, { "name": "VUR8", "type": "synonym", "evidence": [ { "id": "NP_061978", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_061978" } ] }, { "name": "XBS", "type": "synonym", "evidence": [ { "id": "NP_061978", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_061978" } ] }, { "name": "XB", "type": "synonym", "evidence": [ { "id": "NP_061978", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_061978" }, { "id": "P22105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22105" } ] } ], "protein_names": [ { "name": "Tenascin-X", "type": "recommended", "evidence": [ { "id": "P22105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22105/entry#names_and_taxonomy" } ] }, { "name": "Hexabrachion-like protein", "type": "synonym", "evidence": [ { "id": "P22105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22105/entry#names_and_taxonomy" } ] }, { "name": "TN-X", "type": "synonym", "evidence": [ { "id": "P22105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22105/entry#names_and_taxonomy" } ] }, { "name": "growth-inhibiting protein 45", "type": "synonym", "evidence": [ { "id": "NP_061978", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_061978" } ] }, { "name": "hexabrachion-like protein", "type": "synonym", "evidence": [ { "id": "NP_061978", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_061978" } ] }, { "name": "tenascin XB1", "type": "synonym", "evidence": [ { "id": "NP_061978", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_061978" } ] }, { "name": "tenascin XB2", "type": "synonym", "evidence": [ { "id": "NP_061978", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_061978" } ] }, { "name": "tenascin-X isoform 1 precursor", "type": "synonym", "evidence": [ { "id": "NP_061978", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_061978" } ] }, { "name": "tenascin-X", "type": "synonym", "evidence": [ { "id": "NP_061978", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_061978" } ] } ], "function": [ { "annotation": "Aberrant methylation and expression of TNXB promote chondrocyte apoptosis and extracullar matrix degradation in hemophilic arthropathy via AKT signaling. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_061978", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_061978" }, { "database": "PubMed", "id": "38819423", "url": "https://glygen.org/publication/PubMed/38819423" } ] }, { "annotation": "Appears to mediate interactions between cells and the extracellular matrix. Substrate-adhesion molecule that appears to inhibit cell migration. Accelerates collagen fibril formation. May play a role in supporting the growth of epithelial tumors.", "evidence": [ { "database": "UniProtKB", "id": "P22105", "url": "https://www.uniprot.org/uniprotkb/P22105#function" }, { "database": "PubMed", "id": "17033827", "url": "https://glygen.org/publication/PubMed/17033827" } ] }, { "annotation": "Congenital adrenal hyperplasia with a CYP21A2 deletion overlapping the tenascin-X gene: an atypical presentation. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_061978", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_061978" }, { "database": "PubMed", "id": "36259452", "url": "https://glygen.org/publication/PubMed/36259452" } ] }, { "annotation": "Tenascins and osteopontin in biological response in cornea.", "evidence": [ { "database": "RefSeq", "id": "NP_061978", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_061978" }, { "database": "PubMed", "id": "37209968", "url": "https://glygen.org/publication/PubMed/37209968" } ] }, { "annotation": "This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_061978", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_061978" } ] } ], "disease": [ { "disease_id": "DOID:0080731", "recommended_name": { "id": "DOID:0080731", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080731", "name": "Ehlers-Danlos syndrome classic-like 1", "description": "An Ehlers-Danlos syndrome that is characterized by hyperextensible skin, hypermobile joints, and tissue fragility and that has_material_basis_in omozygous or heterozygous mutation in the tenascin-XB gene (TNXB) on chromosome 6p21." }, "synonyms": [ { "id": "MONDO:0011670", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011670", "name": "Ehlers-Danlos syndrome due to tenascin-X deficiency", "description": "" }, { "id": "MONDO:0011670", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011670", "name": "EDS, classic-like type", "description": "" }, { "id": "MONDO:0011670", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011670", "name": "Ehlers-Danlos syndrome due to tenascin-X deficiency", "description": "" }, { "id": "MONDO:0011670", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011670", "name": "Ehlers-Danlos syndrome, classic-like type", "description": "" }, { "id": "MONDO:0011670", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011670", "name": "Ehlers-Danlos syndrome, classic-like, 1", "description": "" }, { "id": "MONDO:0011670", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011670", "name": "EDS due to TNX deficiency", "description": "" }, { "id": "MONDO:0011670", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011670", "name": "EDSCLL", "description": "" }, { "id": "MONDO:0011670", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011670", "name": "Ehlers-Danlos-like syndrome due to tenascin-X deficiency", "description": "" }, { "id": "MONDO:0011670", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011670", "name": "TNX deficiency", "description": "" }, { "id": "MONDO:0011670", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011670", "name": "clEDS", "description": "" }, { "id": "MONDO:0011670", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011670", "name": "classical-like EDS", "description": "" }, { "id": "MONDO:0011670", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011670", "name": "classical-like Ehlers-Danlos syndrome", "description": "" }, { "id": "MIM:606408", "resource": "MIM", "url": "https://www.omim.org/entry/606408", "name": "Ehlers-Danlos syndrome, classic-like, 1", "description": "Ehlers-Danlos syndrome, classic-like, 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "606408", "database": "MIM", "url": "https://www.omim.org/entry/606408" }, { "id": "0080731", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080731" } ] }, { "disease_id": "DOID:12935", "recommended_name": { "id": "DOID:12935", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12935", "name": "alcoholic cardiomyopathy", "description": "" }, "synonyms": [ { "id": "DOID:12935", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12935", "name": "Alcohol-induced heart muscle disease", "description": "" }, { "id": "DOID:12935", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12935", "name": "Dilated cardiomyopathy secondary to alcohol", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "12935", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12935" } ] }, { "disease_id": "DOID:13359", "recommended_name": { "id": "DOID:13359", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13359", "name": "Ehlers-Danlos syndrome", "description": "A collagen disease that is characterized by extremely flexible joints, elastic skin, and excessive bruising caused by a heritable defect in collagen synthesis, which leads to marked healing difficulties. EDS has five cardinal signs, which may be present to some degree in all of the subtypes. These five cardinal signs are skin fragility, blood vessel fragility, skin hyperelasticity, joint hypermobility, and characteristic subcutaneous nodules." }, "synonyms": [ { "id": "DOID:13359", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13359", "name": "Cutis hyperelastica", "description": "" }, { "id": "DOID:13359", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13359", "name": "elastic skin", "description": "" }, { "id": "MONDO:0019567", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019567", "name": "Ehlers-Danlos syndrome, classic type, 1", "description": "Any Ehlers-Danlos syndrome in which the cause of the disease is a mutation in the COL5A1 gene." }, { "id": "MONDO:0019567", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019567", "name": "EDS I", "description": "" }, { "id": "MONDO:0019567", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019567", "name": "EDSCL1", "description": "" }, { "id": "MONDO:0019567", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019567", "name": "Ehlers-Danlos syndrome, classic type, 1", "description": "" }, { "id": "MONDO:0019567", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019567", "name": "Ehlers-Danlos syndrome, type I", "description": "" }, { "id": "MIM:130000", "resource": "MIM", "url": "https://www.omim.org/entry/130000", "name": "Ehlers-Danlos syndrome, classic type, 1", "description": "Ehlers-Danlos syndrome, classic type, 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "13359", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13359" } ] }, { "disease_id": "DOID:9620", "recommended_name": { "id": "DOID:9620", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9620", "name": "vesicoureteral reflux", "description": "A ureteral disease characterized by backward flow of urine from the urinary bladder into the ureter." }, "synonyms": [ { "id": "DOID:9620", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9620", "name": "vesico-ureteral reflux", "description": "" }, { "id": "MONDO:0008653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008653", "name": "vesicoureteral reflux 1", "description": "" }, { "id": "MONDO:0008653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008653", "name": "VUR1", "description": "" }, { "id": "MONDO:0008653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008653", "name": "Vesicoureteral reflux", "description": "" }, { "id": "MONDO:0008653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008653", "name": "vesicoureteral reflux 1", "description": "" }, { "id": "MONDO:0008653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008653", "name": "VUR", "description": "" }, { "id": "MONDO:0010755", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010755", "name": "vesicoureteral reflux, X-linked", "description": "" }, { "id": "MONDO:0010755", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010755", "name": "vesicoureteral reflux, X-linked", "description": "" }, { "id": "MONDO:0010755", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010755", "name": "VURX", "description": "" }, { "id": "MONDO:0012573", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012573", "name": "vesicoureteral reflux 2", "description": "Any vesicoureteral reflux in which the cause of the disease is a mutation in the ROBO2 gene." }, { "id": "MONDO:0012573", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012573", "name": "ROBO2 vesicoureteral reflux (disease)", "description": "" }, { "id": "MONDO:0012573", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012573", "name": "vesicoureteral reflux (disease) caused by mutation in ROBO2", "description": "" }, { "id": "MONDO:0012573", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012573", "name": "vesicoureteral reflux 2", "description": "" }, { "id": "MONDO:0012573", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012573", "name": "vesicoureteral reflux type 2", "description": "" }, { "id": "MONDO:0012573", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012573", "name": "VUR2", "description": "" }, { "id": "MONDO:0013356", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013356", "name": "vesicoureteral reflux 3", "description": "Any vesicoureteral reflux in which the cause of the disease is a mutation in the SOX17 gene." }, { "id": "MONDO:0013356", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013356", "name": "SOX17 vesicoureteral reflux (disease)", "description": "" }, { "id": "MONDO:0013356", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013356", "name": "vesicoureteral reflux (disease) caused by mutation in SOX17", "description": "" }, { "id": "MONDO:0013356", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013356", "name": "vesicoureteral reflux 3", "description": "" }, { "id": "MONDO:0013356", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013356", "name": "vesicoureteral reflux type 3", "description": "" }, { "id": "MONDO:0013356", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013356", "name": "VUR3", "description": "" }, { "id": "MONDO:0013682", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013682", "name": "vesicoureteral reflux 4", "description": "" }, { "id": "MONDO:0013682", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013682", "name": "VUR4", "description": "" }, { "id": "MONDO:0013682", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013682", "name": "vesicoureteral reflux 4", "description": "" }, { "id": "MONDO:0013683", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013683", "name": "vesicoureteral reflux 5", "description": "" }, { "id": "MONDO:0013683", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013683", "name": "VUR5", "description": "" }, { "id": "MONDO:0013683", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013683", "name": "vesicoureteral reflux 5", "description": "" }, { "id": "MONDO:0013684", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013684", "name": "vesicoureteral reflux 6", "description": "" }, { "id": "MONDO:0013684", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013684", "name": "VUR6", "description": "" }, { "id": "MONDO:0013684", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013684", "name": "vesicoureteral reflux 6", "description": "" }, { "id": "MONDO:0014161", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014161", "name": "vesicoureteral reflux 7", "description": "" }, { "id": "MONDO:0014161", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014161", "name": "VUR7", "description": "" }, { "id": "MONDO:0014161", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014161", "name": "vesicoureteral reflux 7", "description": "" }, { "id": "MONDO:0014422", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014422", "name": "vesicoureteral reflux 8", "description": "Any vesicoureteral reflux in which the cause of the disease is a mutation in the TNXB gene." }, { "id": "MONDO:0014422", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014422", "name": "TNXB vesicoureteral reflux (disease)", "description": "" }, { "id": "MONDO:0014422", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014422", "name": "vesicoureteral reflux (disease) caused by mutation in TNXB", "description": "" }, { "id": "MONDO:0014422", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014422", "name": "vesicoureteral reflux 8", "description": "" }, { "id": "MONDO:0014422", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014422", "name": "vesicoureteral reflux type 8", "description": "" }, { "id": "MONDO:0014422", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014422", "name": "VUR8", "description": "" }, { "id": "MONDO:0044660", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0044660", "name": "menstrual cycle-dependent periodic fever", "description": "" }, { "id": "MONDO:0044660", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0044660", "name": "luteal-phase-dependent febrile episode", "description": "" }, { "id": "MONDO:0044660", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0044660", "name": "luteal-phase-dependent periodic fever", "description": "" }, { "id": "MONDO:0044660", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0044660", "name": "menstrual cycle-dependent febrile episode", "description": "" }, { "id": "MONDO:0044660", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0044660", "name": "periodic fever, menstrual cycle dependent", "description": "" }, { "id": "MONDO:0044660", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0044660", "name": "periodic fever, menstrual cycle-dependent", "description": "" }, { "id": "MIM:610878", "resource": "MIM", "url": "https://www.omim.org/entry/610878", "name": "Vesicoureteral reflux 2", "description": "Vesicoureteral reflux 2" }, { "id": "MIM:613674", "resource": "MIM", "url": "https://www.omim.org/entry/613674", "name": "Vesicoureteral reflux 3", "description": "Vesicoureteral reflux 3" }, { "id": "MIM:615963", "resource": "MIM", "url": "https://www.omim.org/entry/615963", "name": "Vesicoureteral reflux 8", "description": "Vesicoureteral reflux 8" }, { "id": "MIM:614674", "resource": "MIM", "url": "https://www.omim.org/entry/614674", "name": "Periodic fever, menstrual cycle-dependent", "description": "Periodic fever, menstrual cycle-dependent" } ], "unlinked_id_list": [], "evidence": [ { "id": "9620", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9620" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [ { "tissue": { "name": "Adult mammalian kidney", "namespace": "UBERON", "id": "0000082", "url": "http://purl.obolibrary.org/obo/UBERON_0000082" }, "score": "81.67", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000168477", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000168477" } ] }, { "tissue": { "name": "Oral cavity", "namespace": "UBERON", "id": "0000167", "url": "http://purl.obolibrary.org/obo/UBERON_0000167" }, "score": "66.47", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000168477", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000168477" } ] }, { "tissue": { "name": "Stomach", "namespace": "UBERON", "id": "0000945", "url": "http://purl.obolibrary.org/obo/UBERON_0000945" }, "score": "95.03", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000168477", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000168477" } ] }, { "tissue": { "name": "Esophagus", "namespace": "UBERON", "id": "0001043", "url": "http://purl.obolibrary.org/obo/UBERON_0001043" }, "score": "98.88", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000168477", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000168477" } ] }, { "tissue": { "name": "Rectum", "namespace": "UBERON", "id": "0001052", "url": "http://purl.obolibrary.org/obo/UBERON_0001052" }, "score": "81.95", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000168477", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000168477" } ] }, { "tissue": { "name": "Urinary bladder", "namespace": "UBERON", "id": "0001255", "url": "http://purl.obolibrary.org/obo/UBERON_0001255" }, "score": "77.93", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000168477", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000168477" } ] }, { "tissue": { "name": "Thyroid gland", "namespace": "UBERON", "id": "0002046", "url": "http://purl.obolibrary.org/obo/UBERON_0002046" }, "score": "89.11", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000168477", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000168477" } ] }, { "tissue": { "name": "Liver", "namespace": "UBERON", "id": "0002107", "url": "http://purl.obolibrary.org/obo/UBERON_0002107" }, "score": "80.88", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000168477", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000168477" } ] }, { "tissue": { "name": "Prostate gland", "namespace": "UBERON", "id": "0002367", "url": "http://purl.obolibrary.org/obo/UBERON_0002367" }, "score": "87.66", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000168477", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000168477" } ] }, { "tissue": { "name": "Thoracic mammary gland", "namespace": "UBERON", "id": "0005200", "url": "http://purl.obolibrary.org/obo/UBERON_0005200" }, "score": "92.14", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000168477", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000168477" } ] } ], "expression_disease": [ { "significant": "No", "trend": "down", "name": "Prostate cancer [DO disease name]", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "database": "BioXpress", "id": "P22105", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/P22105" } ], "disease": [ { "disease_id": "DOID:10283", "recommended_name": { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate." }, "synonyms": [ { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "NGP - new growth of prostate", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "hereditary prostate cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "malignant tumor of the prostate", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "prostate cancer, familial", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "prostate neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "prostatic cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "prostatic neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "tumor of the prostate", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "HPCX1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "prostate cancer, hereditary, X-linked 2", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "HPCX2", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "prostate cancer, hereditary, X-linked 2", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the RNASEL gene." }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "RNASEL familial prostate cancer", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "familial prostate cancer caused by mutation in RNASEL", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, type 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "HPC1", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, type 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "HPC8", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, type 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, susceptibility to, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "HPC3", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, type 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "HPC4", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, type 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "HPC5", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, type 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "HPC6", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "HPC7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, type 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "HPC9", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "HPC10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the EHBP1 gene." }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "EHBP1 familial prostate cancer", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "familial prostate cancer caused by mutation in EHBP1", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, type 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "HPC12", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the MSMB gene." }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "MSMB familial prostate cancer", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "familial prostate cancer caused by mutation in MSMB", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, type 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "HPC13", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "HPC11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "HPC14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "HPC15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0700275", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0700275", "name": "prostate cancer, hereditary", "description": "An instance of prostate cancer that is caused by an inherited genomic modification in an individual. Familial prostate cancer (FPC) is a malignant tumor of the prostate with an early onset. FPC is either asymptomatic or causes mictionary symptoms, erectile dysfunction, bone pain, venous compression and infectious or inflammatory syndrome (for the metastatic forms). It is also characterized by familial antecedents." }, { "id": "MIM:601518", "resource": "MIM", "url": "https://www.omim.org/entry/601518", "name": "Prostate cancer, hereditary, 1", "description": "Prostate cancer, hereditary, 1" }, { "id": "MIM:610997", "resource": "MIM", "url": "https://www.omim.org/entry/610997", "name": "Prostate cancer, hereditary, 9", "description": "Prostate cancer, hereditary, 9" }, { "id": "MIM:611868", "resource": "MIM", "url": "https://www.omim.org/entry/611868", "name": "Prostate cancer, hereditary, 12", "description": "Prostate cancer, hereditary, 12" }, { "id": "MIM:611928", "resource": "MIM", "url": "https://www.omim.org/entry/611928", "name": "Prostate cancer, hereditary, 13", "description": "Prostate cancer, hereditary, 13" }, { "id": "MIM:611955", "resource": "MIM", "url": "https://www.omim.org/entry/611955", "name": "Prostate cancer, hereditary, 11", "description": "Prostate cancer, hereditary, 11" }, { "id": "MIM:176807", "resource": "MIM", "url": "https://www.omim.org/entry/176807", "name": "Prostate cancer", "description": "Prostate cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ] } ] }, { "significant": "Yes", "trend": "down", "name": "Stomach cancer [DO disease name]", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "database": "BioXpress", "id": "P22105", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/P22105" } ], "disease": [ { "disease_id": "DOID:10534", "recommended_name": { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach." }, "synonyms": [ { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "gastric cancer", "description": "" }, { "id": "DOID:10534", 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"http://www.omim.org/entry/606408", "database": "MIM", "categories": [ "Other" ] }, { "id": "615963", "url": "http://www.omim.org/entry/615963", "database": "MIM", "categories": [ "Other" ] }, { "id": "P22105", "url": "https://oglcnac.org/atlas/detail/P22105", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "P22105", "url": "https://www.orthodb.org/?gene=P22105", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46708", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46708", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46708:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46708:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00002cuh", "url": "https://www.rcsb.org/structure/pdb_00002cuh", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00002cui", "url": 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"categories": [ "Glycoproteomics" ] }, { "id": "PR:000056195", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056195", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:P22105", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:P22105", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-HSA-3000178", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-3000178", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_061978", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_061978", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "GLY_000040", "url": "http://data.glygen.org/GLY_000040", "database": "UniCarbKB", "categories": [] }, { "id": "P22105", "url": "https://www.uniprot.org/uniprotkb/P22105", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P22105-1", "url": "https://www.uniprot.org/uniprotkb/P22105-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P22105-2", "url": "https://www.uniprot.org/uniprotkb/P22105-2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P22105-3", "url": "https://www.uniprot.org/uniprotkb/P22105-3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P22105-4", "url": "https://www.uniprot.org/uniprotkb/P22105-4", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMPAQYALTSSLVLLVLLSTARAGPFSSRSNVTLPAPRPPPQPGGHTVGAGVGSPSSQLYEHTVEGGEKQVVFTHRINLPPSTGCGCPPGTEPPVLASEVQALRVRLEILEELVKGLKEQCTGGCCPASAQAGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECHDGSCVCKDGYAGEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRDRDGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKDKDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDRDGQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDGPQVVPVEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNGDGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQGQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGRLQVVPVAANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTVAQGPFDSFVVQYRDTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNFRSPAGGG", "length": 4244, "header": "sp|P22105-3|TENX_HUMAN Isoform 3 of Tenascin-X OS=Homo sapiens OX=9606 GN=TNXB PE=1 SV=5 CANONICAL=P22105-3" }, "isoforms": [ { "isoform_ac": "P22105-1", "url": "https://www.uniprot.org/uniprotkb/P22105/entry#P22105-1", "sequence": { "sequence": "MMPAQYALTSSLVLLVLLSTARAGPFSSRSNVTLPAPRPPPQPGGHTVGAGVGSPSSQLYEHTVEGGEKQVVFTHRINLPPSTGCGCPPGTEPPVLASEVQALRVRLEILEELVKGLKEQCTGGCCPASAQAGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECHDGSCVCKDGYAGEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRDRDGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKDKDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDRDGQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDGPQVVPVEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNGDGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQGQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGRLQVVPVAANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTVAQGPFDSFVVQYRDTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNFRSPAGGG", "length": 4242, "header": "sp|P22105-1|TENX_HUMAN Isoform 1 of Tenascin-X OS=Homo sapiens OX=9606 GN=TNXB PE=1 SV=5 CANONICAL=P22105-3" }, "locus": {} }, { "isoform_ac": "P22105-2", "url": "https://www.uniprot.org/uniprotkb/P22105/entry#P22105-2", "sequence": { "sequence": "MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNFRSPAGGG", "length": 673, "header": "sp|P22105-2|TENX_HUMAN Isoform 2 of Tenascin-X OS=Homo sapiens OX=9606 GN=TNXB PE=1 SV=5 CANONICAL=P22105-3" }, "locus": { "chromosome": "6", "start_pos": 32045219, "end_pos": 32041352, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000451343.4", "url": "https://www.ensembl.org/id/ENST00000451343.4" }, { "database": "Ensembl Peptide", "id": "ENSP00000407685.1", "url": "https://www.ensembl.org/id/ENSP00000407685.1" } ] } }, { "isoform_ac": "P22105-3", "url": "https://www.uniprot.org/uniprotkb/P22105/entry#P22105-3", "sequence": { "sequence": "MMPAQYALTSSLVLLVLLSTARAGPFSSRSNVTLPAPRPPPQPGGHTVGAGVGSPSSQLYEHTVEGGEKQVVFTHRINLPPSTGCGCPPGTEPPVLASEVQALRVRLEILEELVKGLKEQCTGGCCPASAQAGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECHDGSCVCKDGYAGEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRDRDGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKDKDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDRDGQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDGPQVVPVEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNGDGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQGQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGRLQVVPVAANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTVAQGPFDSFVVQYRDTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNFRSPAGGG", "length": 4244, "header": "sp|P22105-3|TENX_HUMAN Isoform 3 of Tenascin-X OS=Homo sapiens OX=9606 GN=TNXB PE=1 SV=5 CANONICAL=P22105-3" }, "locus": { "chromosome": "6", "start_pos": 32098198, "end_pos": 32041352, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000375244.7", "url": "https://www.ensembl.org/id/ENST00000375244.7" }, { "database": "Ensembl Peptide", "id": "ENSP00000364393.3", "url": "https://www.ensembl.org/id/ENSP00000364393.3" } ] } }, { "isoform_ac": "P22105-4", "url": "https://www.uniprot.org/uniprotkb/P22105/entry#P22105-4", "sequence": { "sequence": "MMPAQYALTSSLVLLVLLSTARAGPFSSRSNVTLPAPRPPPQPGGHTVGAGVGSPSSQLYEHTVEGGEKQVVFTHRINLPPSTGCGCPPGTEPPVLASEVQALRVRLEILEELVKGLKEQCTGGCCPASAQAGTGEQGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECHDGSCVCKDGYAGEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRDRDGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKDKDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDRDGQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDGPQVVPVEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNGDGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQGQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGRLQVVPVAANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTVAQGPFDSFVVQYRDTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNFRSPAGGG", "length": 4245, "header": "sp|P22105-4|TENX_HUMAN Isoform 4 of Tenascin-X OS=Homo sapiens OX=9606 GN=TNXB PE=1 SV=5 CANONICAL=P22105-3" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1158, "start_aa": "Thr", "end_pos": 1158, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1158", "evidence": [ { "id": "GLY_001151", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001151" } ], "filter_code": "000000000000000010000.00000000001000.0.01001" }, { "glytoucan_ac": "G43417UB", "type": "O-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1180, "start_aa": "Thr", "end_pos": 1180, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1180", "evidence": [ { "id": "30459171", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30459171" }, { "id": "GLY_000040", "database": "UniCarbKB", "url": "http://data.glygen.org/GLY_000040" } ], "filter_code": "000000000000000010000.0000000.00000000001000.1000000.1100000000.110100100011111100.00010.01001" }, { "glytoucan_ac": "G57321FI", "type": "O-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "RKYKMNLYGLRGRQR", "relation": "attached", "comment": "Data provided by GlycoDomainViewer", "icn3d_view": {}, "start_pos": 1323, "start_aa": "Arg", "end_pos": 1337, "end_aa": "Arg", "evidence": [ { "id": "23584533", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/23584533" }, { "id": "GLY_000040", "database": "UniCarbKB", "url": "http://data.glygen.org/GLY_000040" }, { "id": "10.1038/emboj.2013.79", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1038/emboj.2013.79" } ], "filter_code": "000000000000000000000.0000000.00000000001000.1000000.0100000000.010100100011111110.10000.00001" }, { "glytoucan_ac": "G43417UB", "type": "O-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1364, "start_aa": "Thr", "end_pos": 1364, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1364", "evidence": [ { "id": "30459171", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30459171" }, { "id": "GLY_000040", "database": "UniCarbKB", "url": "http://data.glygen.org/GLY_000040" } ], "filter_code": "000000000000000010000.0000000.00000000001000.1000000.1100000000.110100100011111100.00010.01001" }, { "glytoucan_ac": "G29068FM", "type": "O-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1469, "start_aa": "Thr", "end_pos": 1469, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1469", "evidence": [ { "id": "30459171", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30459171" }, { "id": "GLY_000040", "database": "UniCarbKB", "url": "http://data.glygen.org/GLY_000040" } ], "filter_code": "000000000000000010000.0000000.00000000001000.1000000.0100000000.111111100111111111.00010.01001" }, { "glytoucan_ac": "G43417UB", "type": "O-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1469, "start_aa": "Thr", "end_pos": 1469, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1469", "evidence": [ { "id": "30459171", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30459171" }, { "id": "GLY_000040", "database": "UniCarbKB", "url": "http://data.glygen.org/GLY_000040" } ], "filter_code": "000000000000000010000.0000000.00000000001000.1000000.1100000000.110100100011111100.00010.01001" }, { "glytoucan_ac": "G29068FM", "type": "O-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1569, "start_aa": "Thr", "end_pos": 1569, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1569", "evidence": [ { "id": "30459171", "database": "PubMed", "url": 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U.S.A.", "date": "1989", "authors": "Morel Y, Bristow J, Gitelman SE, Miller WL", "evidence": [ { "database": "UniProtKB", "id": "P22105", "url": "https://www.uniprot.org/uniprotkb/P22105" } ], "reference": [ { "type": "PubMed", "id": "2475872", "url": "https://glygen.org/publication/PubMed/2475872" } ] }, { "title": "Diverse HLA-I Peptide Repertoires of the APC Lines MUTZ3-Derived Immature and Mature Dendritic Cells and THP1-Derived Macrophages.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2016-09-15", "authors": "Nyambura Lydon Wainaina, Jarmalavicius Saulius, Baleeiro Renato Brito, Walden Peter", "evidence": [ { "database": "IEDB", "id": "549710", "url": "https://www.iedb.org/epitope/549710" } ], "reference": [ { "type": "PubMed", "id": "27543614", "url": "https://glygen.org/publication/PubMed/27543614" } ] }, { "title": "Immunogenic HLA-DR-Presented Self-Peptides Identified Directly from Clinical Samples of Synovial Tissue, Synovial Fluid, or Peripheral Blood in Patients with Rheumatoid Arthritis or Lyme Arthritis.", "journal": "Journal of proteome research", "date": "2017-01-06", "authors": "Wang Qi, Drouin Elise E, Yao Chunxiang, Zhang Jiyang, Huang Yu, Leon Deborah R, Steere Allen C, Costello Catherine E", "evidence": [ { "database": "IEDB", "id": "592315", "url": "https://www.iedb.org/epitope/592315" }, { "database": "IEDB", "id": "592355", "url": "https://www.iedb.org/epitope/592355" } ], "reference": [ { "type": "PubMed", "id": "27726376", "url": "https://glygen.org/publication/PubMed/27726376" } ] }, { "title": "Purification of soluble HLA class I complexes from human serum or plasma deliver high quality immuno peptidomes required for biomarker discovery.", "journal": "Proteomics", "date": "2017-01", "authors": "Ritz Danilo, Gloger Andreas, Neri Dario, Fugmann Tim", "evidence": [ { "database": "IEDB", "id": "877836", "url": "https://www.iedb.org/epitope/877836" } ], "reference": [ { "type": "PubMed", "id": "27862975", "url": "https://glygen.org/publication/PubMed/27862975" } ] }, { "title": "A novel strategy for global mapping of O-GlcNAc proteins and peptides using selective enzymatic deglycosylation, HILIC enrichment and mass spectrometry identification.", "journal": "Talanta", "date": "2017", "authors": "Shen B, Zhang W, Shi Z, Tian F, Deng Y, Sun C, Wang G, Qin W, Qian X", "evidence": [ { "database": "O-GlcNAc Database", "id": "P22105", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22105" } ], "reference": [ { "type": "PubMed", "id": "28411811", "url": "https://glygen.org/publication/PubMed/28411811" } ] }, { "title": "Quantitative proteomics identifies altered O-GlcNAcylation of structural, synaptic and memory-associated proteins in Alzheimer's disease.", "journal": "The Journal of pathology", "date": "2017", "authors": "Wang S, Yang F, Petyuk VA, Shukla AK, Monroe ME, Gritsenko MA, Rodland KD, Smith RD, Qian WJ, Gong CX, Liu T", "evidence": [ { "database": "O-GlcNAc Database", "id": 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"High-throughput and Sensitive Immunopeptidomics Platform Reveals Profound Interferon\u03b3-Mediated Remodeling of the Human Leukocyte Antigen (HLA) Ligandome.", "journal": "Molecular & cellular proteomics : MCP", "date": "2018-03", "authors": "Chong Chloe, Marino Fabio, Pak HuiSong, Racle Julien, Daniel Roy T, M\u00fcller Markus, Gfeller David, Coukos George, Bassani-Sternberg Michal", "evidence": [ { "database": "IEDB", "id": "1857255", "url": "https://www.iedb.org/epitope/1857255" }, { "database": "IEDB", "id": "1919717", "url": "https://www.iedb.org/epitope/1919717" } ], "reference": [ { "type": "PubMed", "id": "29242379", "url": "https://glygen.org/publication/PubMed/29242379" } ] }, { "title": "Large-scale intact glycopeptide identification by Mascot database search.", "journal": "Scientific reports", "date": "2018", "authors": "Bollineni RC, Koehler CJ, Gislefoss RE, Anonsen JH, Thiede B", "evidence": [ { "database": "GlyConnect", "id": "1794", "url": 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Kohlbacher Oliver, Kanz Lothar, K\u00f6nigsrainer Alfred, Rammensee Hans-Georg, Stevanovi\u0107 Stefan, Haen Sebastian P", "evidence": [ { "database": "IEDB", "id": "877836", "url": "https://www.iedb.org/epitope/877836" } ], "reference": [ { "type": "PubMed", "id": "29789417", "url": "https://glygen.org/publication/PubMed/29789417" } ] }, { "title": "Mapping the O-glycoproteome using site-specific extraction of O-linked glycopeptides (EXoO).", "journal": "Molecular systems biology", "date": "2018", "authors": "Yang W, Ao M, Hu Y, Li QK, Zhang H", "evidence": [ { "database": "UniCarbKB", "id": "GLY_000040", "url": "http://data.glygen.org/GLY_000040" } ], "reference": [ { "type": "PubMed", "id": "30459171", "url": "https://glygen.org/publication/PubMed/30459171" } ] }, { "title": "Specific MHC-I Peptides Are Induced Using PROTACs.", "journal": "Frontiers in immunology", "date": "2018", "authors": "Jensen Stephanie M, Potts Gregory K, Ready Damien B, Patterson Melanie J", "evidence": [ { 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Deceneux Cyril, Aranha Ritchlynn, Duscharla Divya, Wong Stephen Q, Chen Weisan, Ramarathinam Sri H, Lim Kam Sian Terry C C, Croft Nathan P, Li Chen, Ayala Rochelle, Cebon Jonathan S, Purcell Anthony W, Schittenhelm Ralf B, Behren Andreas", "evidence": [ { "database": "IEDB", "id": "1973119", "url": "https://www.iedb.org/epitope/1973119" }, { "database": "IEDB", "id": "1976237", "url": "https://www.iedb.org/epitope/1976237" }, { "database": "IEDB", "id": "1991172", "url": "https://www.iedb.org/epitope/1991172" } ], "reference": [ { "type": "PubMed", "id": "32938616", "url": "https://glygen.org/publication/PubMed/32938616" } ] }, { "title": "CIITA-Transduced Glioblastoma Cells Uncover a Rich Repertoire of Clinically Relevant Tumor-Associated HLA-II Antigens.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Forlani Greta, Michaux Justine, Pak HuiSong, Huber Florian, Marie Joseph Elodie Lauret, Ramia Elise, Stevenson Brian J, Linnebacher Michael, Accolla 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"url": "https://glygen.org/publication/PubMed/35580925" } ] }, { "title": "Congenital adrenal hyperplasia with a CYP21A2 deletion overlapping the tenascin-X gene: an atypical presentation.", "journal": "Journal of pediatric endocrinology & metabolism : JPEM", "date": "2022-10-20", "authors": "Ivo Catarina Rodrigues, Fitas Ana Laura, Madureira In\u00eas, Diamantino Catarina, Gomes Susana, Gon\u00e7alves Jo\u00e3o, Lopes Lurdes", "evidence": [ { "database": "RefSeq", "id": "NP_061978", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_061978" } ], "reference": [ { "type": "PubMed", "id": "36259452", "url": "https://glygen.org/publication/PubMed/36259452" } ] }, { "title": "Integrated glycoproteomic characterization of clear cell renal cell carcinoma.", "journal": "Cell reports", "date": "2023-05-30", "authors": "Lih T Mamie, Cho Kyung-Cho, Schnaubelt Michael, Hu Yingwei, Zhang Hui", "evidence": [ { "database": "PDC", "id": "PDC000471", "url": 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"id": "P22105", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22105" } ], "reference": [ { "type": "PubMed", "id": "37217939", "url": "https://glygen.org/publication/PubMed/37217939" } ] }, { "title": "Studying the O-GlcNAcome of human placentas using banked tissue samples.", "journal": "Glycobiology", "date": "2024-01-22", "authors": "Luna Sarai, Malard Florian, Pereckas Michaela, Aoki Mayumi, Aoki Kazahiro, Olivier-Van Stichelen Stephanie", "evidence": [ { "database": "O-GlcNAc Database", "id": "P22105", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22105" } ], "reference": [ { "type": "PubMed", "id": "38253038", "url": "https://glygen.org/publication/PubMed/38253038" } ] }, { "title": "Aberrant methylation and expression of TNXB promote chondrocyte apoptosis and extracullar matrix degradation in hemophilic arthropathy via AKT signaling.", "journal": "eLife", "date": "2024-05-31", "authors": "Chen Jiali, Zeng Qinghe, Wang Xu, Xu Rui, Wang Weidong, Huang Yuliang, Sun Qi, Yuan Wenhua, Wang Pinger, Chen Di, Tong Peijian, Jin Hongting", "evidence": [ { "database": "RefSeq", "id": "NP_061978", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_061978" } ], "reference": [ { "type": "PubMed", "id": "38819423", "url": "https://glygen.org/publication/PubMed/38819423" } ] }, { "title": "Cartilage proteoglycan binding region and link protein. Radioimmunoassays and the detection of masked determinants in aggregates.", "journal": "The Biochemical journal", "date": "1983", "authors": "Ratcliffe A, Hardingham T", "evidence": [ { "database": "Reactome", "id": "R-HSA-3000178", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-3000178" } ], "reference": [ { "type": "PubMed", "id": "6193777", "url": "https://glygen.org/publication/PubMed/6193777" } ] }, { "title": "Specific inhibition of type I and type II collagen fibrillogenesis by the small proteoglycan of tendon.", "journal": "The Biochemical journal", "date": "1984", "authors": "Vogel KG, Paulsson M, Heinegard D", "evidence": [ { "database": "Reactome", "id": "R-HSA-3000178", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-3000178" } ], "reference": [ { "type": "PubMed", "id": "6439184", "url": "https://glygen.org/publication/PubMed/6439184" } ] }, { "title": "Binding of tenascin-C to soluble fibronectin and matrix fibrils.", "journal": "The Journal of biological chemistry", "date": "1995", "authors": "Chung CY, Zardi L, Erickson HP", "evidence": [ { "database": "Reactome", "id": "R-HSA-3000178", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-3000178" } ], "reference": [ { "type": "PubMed", "id": "7499434", "url": "https://glygen.org/publication/PubMed/7499434" } ] }, { "title": "The distribution of tenascin-X is distinct and often reciprocal to that of tenascin-C.", "journal": "The Journal of cell biology", "date": "1994", "authors": "Matsumoto K, Saga Y, Ikemura T, Sakakura T, Chiquet-Ehrismann R", "evidence": [ { "database": "MatrixDB", "id": "GAG_1", "url": "https://matrixdb.univ-lyon1.fr/biomolecule/GAG_1" } ], "reference": [ { "type": "PubMed", "id": "7512972", "url": "https://glygen.org/publication/PubMed/7512972" } ] }, { "title": "Tenascin-R (J1 160/180 inhibits fibronectin-mediated cell adhesion--functional relatedness to tenascin-C.", "journal": "Journal of cell science", "date": "1994", "authors": "Pesheva P, Probstmeier R, Skubitz AP, McCarthy JB, Furcht LT, Schachner M", "evidence": [ { "database": "Reactome", "id": "R-HSA-3000178", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-3000178" } ], "reference": [ { "type": "PubMed", "id": "7527058", "url": "https://glygen.org/publication/PubMed/7527058" } ] }, { "title": "Alpha v beta 1 is a receptor for vitronectin and fibrinogen, and acts with alpha 5 beta 1 to mediate spreading on fibronectin.", "journal": "Journal of cell science", "date": "1995", "authors": "Marshall JF, Rutherford DC, McCartney AC, Mitjans F, Goodman SL, Hart IR", "evidence": [ { "database": "Reactome", "id": "R-HSA-3000178", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-3000178" } ], "reference": [ { "type": "PubMed", "id": "7542669", "url": "https://glygen.org/publication/PubMed/7542669" } ] }, { "title": "The human integrin alpha 8 beta 1 functions as a receptor for tenascin, fibronectin, and vitronectin.", "journal": "The Journal of biological chemistry", "date": "1995", "authors": "Schnapp LM, Hatch N, Ramos DM, Klimanskaya IV, Sheppard D, Pytela R", "evidence": [ { "database": "Reactome", "id": "R-HSA-3000178", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-3000178" } ], "reference": [ { "type": "PubMed", "id": "7559467", "url": "https://glygen.org/publication/PubMed/7559467" } ] }, { "title": "The alpha v beta 5 integrin receptor regulates receptor-mediated endocytosis of vitronectin.", "journal": "The Journal of biological chemistry", "date": "1993", "authors": "Panetti TS, McKeown-Longo PJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-3000178", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-3000178" } ], "reference": [ { "type": "PubMed", "id": "7685013", "url": "https://glygen.org/publication/PubMed/7685013" } ] }, { "title": "Tenascin-X: a novel extracellular matrix protein encoded by the human XB gene overlapping P450c21B.", "journal": "J. Cell Biol.", "date": "1993", "authors": "Bristow J, Tee M K, Gitelman S E, Mellon S H, Miller W L", "evidence": [ { "database": "UniProtKB", "id": "P22105", "url": "https://www.uniprot.org/uniprotkb/P22105" } ], "reference": [ { "type": "PubMed", "id": "7686164", "url": "https://glygen.org/publication/PubMed/7686164" } ] }, { "title": "Endothelial cell attachment and spreading on human tenascin is mediated by alpha 2 beta 1 and alpha v beta 3 integrins.", "journal": "Journal of cell science", "date": "1993", "authors": "Sriramarao P, Mendler M, Bourdon MA", "evidence": [ { "database": "Reactome", "id": "R-HSA-3000178", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-3000178" } ], "reference": [ { "type": "PubMed", "id": "7693733", "url": "https://glygen.org/publication/PubMed/7693733" } ] }, { "title": "Interaction of biglycan with type I collagen.", "journal": "The Journal of biological chemistry", "date": "1995", "authors": "Schonherr E, Witsch-Prehm P, Harrach B, Robenek H, Rauterberg J, Kresse H", "evidence": [ { "database": "Reactome", "id": "R-HSA-3000178", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-3000178" } ], "reference": [ { "type": "PubMed", "id": "7852349", "url": "https://glygen.org/publication/PubMed/7852349" } ] }, { "title": "The expression of functional link protein in a baculovirus system: analysis of mutants lacking the A, B and B' domains.", "journal": "The Biochemical journal", "date": "1994", "authors": "Grover J, Roughley PJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-3000178", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-3000178" } ], "reference": [ { "type": "PubMed", "id": "8002934", "url": "https://glygen.org/publication/PubMed/8002934" } ] }, { "title": "Interaction of heparin cofactor II with biglycan and decorin.", "journal": "The Journal of biological chemistry", "date": "1993", "authors": "Whinna HC, Choi HU, Rosenberg LC, Church FC", "evidence": [ { "database": "Reactome", "id": "R-HSA-3000178", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-3000178" } ], "reference": [ { "type": "PubMed", "id": "8440685", "url": "https://glygen.org/publication/PubMed/8440685" } ] }, { "title": "Sequences promoting the transcription of the human XA gene overlapping P450c21A correctly predict the presence of a novel, adrenal-specific, truncated form of tenascin-X.", "journal": "Genomics", "date": "1995", "authors": "Tee MK, Thomson AA, Bristow J, Miller WL", "evidence": [ { "database": "UniProtKB", "id": "P22105", "url": "https://www.uniprot.org/uniprotkb/P22105" } ], "reference": [ { "type": "PubMed", "id": "8530023", "url": "https://glygen.org/publication/PubMed/8530023" } ] }, { "title": "Differential effects of the integrins alpha9beta1, alphavbeta3, and alphavbeta6 on cell proliferative responses to tenascin. Roles of the beta subunit extracellular and cytoplasmic domains.", "journal": "The Journal of biological chemistry", "date": "1996", "authors": "Yokosaki Y, Monis H, Chen J, Sheppard D", "evidence": [ { "database": "Reactome", "id": "R-HSA-3000178", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-3000178" } ], "reference": [ { "type": "PubMed", "id": "8798654", "url": "https://glygen.org/publication/PubMed/8798654" } ] }, { "title": "Alternate promoters and alternate splicing of human tenascin-X, a gene with 5' and 3' ends buried in other genes.", "journal": "Hum. Mol. Genet.", "date": "1996", "authors": "Speek M, Barry F, Miller WL", "evidence": [ { "database": "UniProtKB", "id": "P22105", "url": "https://www.uniprot.org/uniprotkb/P22105" } ], "reference": [ { "type": "PubMed", "id": "8923003", "url": "https://glygen.org/publication/PubMed/8923003" } ] }, { "title": "Interaction of cartilage matrix protein with aggrecan. Increased covalent cross-linking with tissue maturation.", "journal": "The Journal of biological chemistry", "date": "1996", "authors": "Hauser N, Paulsson M, Heinegard D, Morgelin M", "evidence": [ { "database": "Reactome", "id": "R-HSA-3000178", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-3000178" } ], "reference": [ { "type": "PubMed", "id": "8943283", "url": "https://glygen.org/publication/PubMed/8943283" } ] }, { "title": "Localization of a binding site for the proteoglycan decorin on collagen XIV (undulin).", "journal": "The Journal of biological chemistry", "date": "1997", "authors": "Ehnis T, Dieterich W, Bauer M, Kresse H, Schuppan D", "evidence": [ { "database": "Reactome", "id": "R-HSA-3000178", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-3000178" } ], "reference": [ { "type": "PubMed", "id": "9252349", "url": "https://glygen.org/publication/PubMed/9252349" } ] }, { "title": "The C-type lectin domains of lecticans, a family of aggregating chondroitin sulfate proteoglycans, bind tenascin-R by protein-protein interactions independent of carbohydrate moiety.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "1997", "authors": "Aspberg A, Miura R, Bourdoulous S, Shimonaka M, Heinegard D, Schachner M, Ruoslahti E, Yamaguchi Y", "evidence": [ { "database": "Reactome", "id": "R-HSA-3000178", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-3000178" } ], "reference": [ { "type": "PubMed", "id": "9294172", "url": "https://glygen.org/publication/PubMed/9294172" } ] }, { "title": "Mapping of a defined neurocan binding site to distinct domains of tenascin-C.", "journal": "The Journal of biological chemistry", "date": "1997", "authors": "Rauch U, Clement A, Retzler C, Frohlich L, Fassler R, Gohring W, Faissner A", "evidence": [ { "database": "Reactome", "id": "R-HSA-3000178", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-3000178" } ], "reference": [ { "type": "PubMed", "id": 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musculus", "sequence": { "sequence": "MAAQCTPSILTILVLLGLARAGPFSPRSNVTLPAPRPPPKPGGPSSQLYEHTVEGGEKQVVFTHRINLPPSAGCGCPPGSEPPVPASEVQALRVRLEILEELVKGLKEHCTGGCCPTAAQAGTGQTDVRSLCSLHGVFDLSRCACSCEPGWGGPTCSDPTDTKTPTSSPPSKSCPEDCNDQGRCVRGRCVCFPGYSGPSCSWPSCPGDCQGRGRCVKGVCVCRAGFSGPDCSQRSCPRNCNQRGRCEEGRCVCDPGYSGEDCGVRSCPRGCSQRGRCENGLCVCNPGYSGEDCGVRNCPRGCSQRGRCEDGRCVCDPGYSGEDCSMRTCPWDCGDGGRCVDGRCVCWPGYSGEDCSTRTCPRDCRGRGRCEDGECICDAGYSGDDCGVRSCPGDCNQRGHCEDGRCVCWPGYTGADCSTRACPRDCRGRGRCEDGVCVCHAGYSGEDCGVRSCPGDCRGRGNCESGRCVCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGHCENGVCVCAVGYSGDDCSTRSCPSDCRGRGQCLNGLCECDEGYSGEDCGIRRCPRDCSQHGVCQDGLCMCHAGYAGEDCSIRTCPADCRRRGRCEDGRCVCNPGYTGPACATRTCPADCRGRGRCVQGVCMCYVGYSGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRSRGECIQGRCVCQEGYAGDDCGEEIPAIQNMRMHLLEETTVRTEWTRAPGPVDAYEIQFIPMTEGVSPPFTARVPSSASAYDQRGLAPGQDYQVTVRALRGTSWGPPASKTITTMIDGPQDLRVVAVTPTTLDLSWLRPQAEVDRFVVSYVSAGNQRVRLEVPPEADRTQLTDLMPGVEYVVTVTAERGHAVSYPASIRANTAPGHYSYPEVRPPAPPPNPRPRPRWPSRPLPSPETDEKEWHLRPRLPQPPRRPWGNLTTELSRFRGTVQDLEHHLRTHGYPLRANQTYASVARYIHEFLKRHQTAGAPASQPRHPHPTTSPTQNTRKRDSEQGAVGPASDGAHPVTTARHPKPEVLGSAADGSLIVSLDGLRGQFERVVLRWRPLLPAKGPSGELTVDGSERTVRLPNLRPGTTYHVEVHGVRAGQTSKSYAFITTTTTTTTGSLPSGLLEATDEPPPSGPSTTQGAQAPILILEHHPLGELKVLGRDKAGRLSVAWTAQPDSFAHFQLRMQVAEGPWAHEELLPGDVQQALVPPPPPGAPYKLFLHGITPGGKISVPITYQGIMDRAQEQPGKPSVQPRLGELTVTGLTSDSLLLHWTVPEGEFDSFLIQYKDKDGPQAISVEGPQRSTPISGLEPGRKYKFILYGLIGKKRHGPLMAEAKILIQSDPDPGSPPRLGELWVTDPTPHSLHLSWTVLGGQFDSFVVQYRDKEGQPRVVPVEGPDRSVVISPLDPNRKYRFTLFGIANKKRYGPLTADGTTAAETKEESSEPPRLGELTVTGVTPDSLRLSWTVARGPFDSFVILYKDAQGQPQSVPIEGDENEVTVPGLESNRKYKMNLYGLRGRQRVGPVSVVAKTAPPDVVDQPLSPPEPSTEAPEPPEKPLLRELIVTDTTPNSLSLSWTVSEGQFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIHSGQRVGPVSVVGVTAAEEEPPSPTEPSTEAPEPTEEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKSSDGRPQVMRVGGQEREVIVRDLDPGHKYKMNLYGLHEGHRVGPVSTVGTTDKQPEEKPPLEPRLEELTVTGVTPNSVSLSWIVPEGQFDSFVVQYQDRDGQPREVPLTAEQREVTVLDLDPARIYKMNFYGLHGRRRVGPLSVSAMTAPAPATEASKLLPEPRLGELTVTDVTPDSVGLLWTVPEGEFDSFTVQYKDRDGQPHVVSVAADLREVTIPGLEPSRKYKFLLFGVQDGKRRSQVSVEAKTATHDDTSPGAPPRLGELWVTDPTTDSLRLSWTVPEGHFDSFVVQFKDKSGPRVVPVKGQERTATITALDAGRKYRFLLYGLLGRKRFGPLTAEGITEPTNAADHTKSRLGEELRVTGVTQNSVDLSWTVSEGQFDSFVVQYKDRDGQSQVVPVDGSHREVRVSGLDPGRRYKLLLYGLRDSKRVGPLSVIAVTDPRETTEAWTEVPTTSTPAAVPRLGELRVEEATPHSLHLSWVVTEGEFNSFEVQYTDRDGQLRVASTEGDQTDITLTGLESNHRYLITLYGFHDGQPVGSAQIEALTVPWEEEEEEEESTEPPTMTPEPRPQLGELTVTDATPDSLSLSWTVPEGQFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKLNLYGIHSGQRFGPVSTVGVTAAVEEPPSPTEPSTEAPEPTEEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVMRVGGQEREVIVRDLDPGRKYKMNLYGLHEGRRVGPVSTVGVTDPKEEPTDASSLKPRLEELTVTDATPDSLSLSWTVPEGQFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIYSGQRVGPVSAVGVTAAEEEPPSPTEPRTEAPEPTEAPEPTEEPRLGELTVTGSSPDSLSLSWTIPKGDFDSFTVQYKDSDGRPQVIRVRGQEREVIVRDLDPGRKYKMNLYGLHEGRRVGPVSTIGVTAPEEEALTTQAVPTTTPEPPPKKPHLGELTVTDATPDSLSLSWTVPEEQFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIYSGQRVGPVSVVGVTAAEEEPPSPEPSTEAPEPTEAPEPTEEPLLGELTVTGSSPDSLILSWTIPKGDFDSFTVQYKDSDGRPQVMRVGGQEREVIVRDLDPGRKYKMNLYGLHEGRRVGPVSTVGVTEEEATTTQAEPIVTTEPPPKKPHLGVLTVTDATPDSLSLSWTVPEAHFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIYSGQRVGPVSAVGVTAAEEEPPSPTEPSTEAPESTEEPLLGELTVTGSSPDSLSLSWTVPQGEFDSFTVQYKDSDGRPQVMRVGGQEREVIVRDLDPGRKYKMNLYGLHEGRRVGPVSTVGMTEKEALTTQVVPTTTPEPPPKKPHLGELTVTDATSDSLSLSWTVPEGQFEQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIHSGQRFGPVSTVGVTTAVEEPPSPTEPSIEAPEPTEEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVMRVGGQEREVIVRDLDPGRKYKMNLYGLHEGRRVGPVSTVGVTASLTTEPPIEPRLGELAAVEVTSSTVHLSWTVAQGPFDSFLVQYKDTQGQPQMVPVSGDLGEVTVSGLEPARKYKFLLFGLKDGKRHGPVSTEAKTVSDAKLLPRLGELTVTDTTQNSVGLSWTVPEGEFDSFLVQYKNRGGQVQVVPAAADQREVTISSLEPNRKYRFLLFGLIGLKRLGPVSVEGTTAPVEKTPQPRLGELSVTEETSDSMHLSWSVAQGPFDSFLVQYKDRDGQLQTVSLAADQREVTIEGLQPGRKYKFLLYGLTGGKRLGPISALGVTASEVDISAPDHTEPPHAPGLGTLAVTEATPDSLRLSWAVARGPFDSFVVQYQDTENETQALLVDGDQDKVLISGLEPKTSYKFFLYGLREGTRHGPVSVEGTTDPVPAGQGPGDPGPRLSQLSVSDVTTSSLRLNWEAPLGAFDSFLLRFGVPLLSTLEQNPRTLQQRELMVPGVRRSAMLRDLRPGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSDIGETSAKVKWVPPTSRVDSFKISYQLADGGEPQSVQVDGRTQTQILQGLIPDTRYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTDGSALLHWKPPHKPVDKYDVEVESPGAPPLQASAPGSAVDYPLTDLALDTNYTATVRGLRGPNFTSPASITFTTGLKPPQDLEAKEVTPRTALLTWTEPEVPPTGYLLSFDTPGGQIQEILLPAGTTSHRLLRLFPSTFYSAQLRAIWGESLTPPVLTSFTTGGLRIPFPRDCGEELKNGPSASKTTTIFLNGNRERPLDVFCDMETDGGGWLVFQRRMDGQTDFWRDWEEYAHGFGNISGEFWLGNEALHSLTQAGDYSLRVDLRAGKEAVFAQYDFFRVDSAKENYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNNLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNFQVPTRGT", "length": 4356 }, "evidence": [ { "id": "MGI:1932137", "url": "https://alliancegenome.org/gene/MGI:1932137#orthology", "database": "AGR" }, { "id": "HGNC:11976", "url": "https://alliancegenome.org/gene/HGNC:11976#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070103-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070103-5#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8I6AJ44-1", "protein_name": "Tenascin XB", "gene_name": "Tnxb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAQCTPSILTVLVLLGTARGGPFSPRSNVTLPVPRPPPQPGGPSSQLYEHTVEGGEKQVVFTHRINLPPSAGCGCPPGSEPPVPASEVQALRVRLEILEELVKGLKEHCSGGCCPTAAQAGTGQTDVRSLCSLHGVFDLSRCACSCEPGWGGPTCSDPTDTKTPTSAPPSASKACPEDCNDQGRCVRGRCVCFPGYSGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRNCNQRGRCEEGRCVCDPGYSGEDCGVRSCPRGCSQRGRCENGRCVCNPGYSGEDCGVRSCPRGCSQRGRCEDGRCVCDPGYSGEDCSVRSCPWDCGDGGRCVDGRCVCWPGYSGEDCSTRTCPRDCRGRGRCEDGECICDPGYSGDDCGVRSCPGDCNQRGHCEDGRCVCWPGYTGADCSTRACPRDCRGRGRCENGVCVCHAGYSGEDCGVRSCPGDCRGRGSCESGRCVCWPGYTGRDCGMRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGHCEDGVCVCAVGYSGDDCSTRSCPSGCRGRGRCLDGLCVCDEGYSGEDCSVRLCPRDCSQHGVCQDGLCVCHAGYAGEDCSIRTCPADCHRRGRCEDGRCVCNPGYTGPACATRTCPADCRGRGRCVQGVCVCYAGYSGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECVQGTCVCQDGYAGDDCGEEIPAIQNMRMHLLEETTVRTEWTRVPGPVDAYEIQFIPMTEGVSPPFTARVPSSASAYDQRGLAPGQDYQVTVRALRGTSWGPPTSKTITTMIDGPQDLQVVAVTPTTLDLSWLRPQAEVDRFVVSYVSAGNQRVRLEVPPEADRTQLTDLMPGVEYVVTVTAERGHAVSYPASVRANTAPGHYSYPEVRPPVPPPNPRPRPPRPSRPLLPPEGGEKEWHLRPSLPQPPRRPWGNLTAELGRFRGTVQDLERHLRTHGYPLRANQTYASVARHIHEFLKRHQTAGAPASQPRHPHPTTSPTQSTRKRDSDQGAVGPASYGAHPVTATRHPKPEVLGSAADGSLIVSLDGLRGQFERVVLRWRPLPPAKGPSGELTVDGSERTVRLPNLRPGTTYHVEVHGVRAGQTSKSYAFITTTATTTGSLPSGLLEATDEPPPSGPSTTQGAQAPILILEHHPLGELKVLGRDKAGRLRVAWTAQPDSFAHFQLRMQVAEGPWAHEELLPGHVHQALVPPPPPGSPYKLFLQGITPGGEPSVPITYQGIMDRAEVQPGKSSVLPRLGELTVTGLTSDSLLLHWTVPEGEFDSFLIQYKDKDGPRAIPVEGPQRSAPVTALEPGRKYKFILYGLIGKKRHGPLIAEAKILLQSDPDSGSPPRLGELWVTDPTPHSLHLSWTVLGGQFDSFMVQYRDKEGQPHVVPVEGPERSVVISPLDPNHKYRFTLFGVANKKRYGPLTADGTTASEPKEESSEPPRLGELTVTGVTPDSLRLSWTVARGPFDSFVILYKDAQGQPQSVPIEGDENEVTVPGLESNRKYKMNLYGLRGRQRVGPVSVVAKTAPPEIVDQTSSPTEPSTQAPEPPKKPLLGELTVTDTTPNSLSLSWTVPEGQFDQFVIQYKNGDGQPKVVRVPGYEDQVTISGLEPDHKYKMNLYGIHSGQRVGPVSVTGVTDAEEEPPSPTELSIEAPEPTETPEPTEEEEPLLGELTVTGSSPDSLSLSWTVPQGHFDSFTVQYKDSNGRPQVMRVGGQEREAIVRDLDPGRKYKMNLYGFHEGRRVGPVSTVGVTDPQPEEKTPREPHLEELAVTGVTPNSVSLSWVVPEGQFDSFVVQYQDGDGQPQEVPVTAEQREVTILDLDPERVYKMNLYGLYGRQRVGPLSVSAVTDPLPEAPAPVTEASKLVPEPRLGELAVTDVTPDSVGLLWTVPEGEFDSFMVQYKDRDGQPHVESVAADLREVTVPGLEPSRKYKFLLFGVRDGKRHSQVSVEAKTAAREDTSPEAPPRLGELWVTEPTTDSLRLSWTVPEGHFDSFVVQFKDKSGPRVVPVNGQELTTTITALDAGRKYRFLLYGLLGKKRFGPLTAEGNTESMNAVDHTREKHPTKPRLGEELRVTSVTQNSVDLSWTVSEGQFDSFVVQYKNRDGQSQVVPVDGSHREVRVSGLDPGRRYKLLLYGLRDGKRVGPLSVIAVTDPRETTEAWTEVPTTSTPATVPRLGELRVEEATPHSLHLSWVVSEGEFNSFEVQYTDRDGQLRVVSTEGDQSDITLTGLDSDHRYLITLYGFHDGQRVGPAQIEALTVPREEEEDEEEEPTESPTTTPEPKPRLGELTVTDTTPNSLSLSWTVPEGQFDQFVIQYKNGDGQPKVVRVPGYEDQVTISGLEPDHKYKMNLYGIHSGQRVGPVSTVGVTAAEEELPSPTEPSTEAPEPTEEEEPLLGELTVTGSSPDSLSLSWTVPQGHFDSFTVQYKDSNGRPQVVRVGGQEREAIVRDLDPGRKYKMNLYGFHEGHRVGPVSTVGVTNPEEEPTDAPSPKPRLGELTVTDATPDSLSLSWTVPEGQFDQFVIQYKNGDGQPKVVRVPGYEDQVTISGLEPDHKYKMNLYGIHSGQRVGPVSVTGVTAADEEPPSPEPSTEAPEPTEAPEPTEEEPLLGELTVTGSSPDSLSLSWTVPQGHFDSFTVQYKDSNGRPQVVRVGGQEREAIVRDLDPGRKYKMNLYGFYEGSRVGPVSTVGVTDSEEEAPTTQAVPTTTPEPPPKKPLLGELTVTDATPDSLSLSWTVPEGQFDQFVIQYKNGDGQPKVVRVPGYEDQVTISGLEPDHKYKMNLYGIHSGQRVGPVSVTGVTAAEEEPPSPTEPSTEAPEPTEAPEPTEEELLLGELTVTGTSPDSLSLSWTVPQGHFDSFTVQYKDSSGRPQVMRIGGQEREAIVTDLDPGRKYKMNLYGFHEGRRVGPVSTVGVTEEEAMTTQAVPTVTTEPPPEKPRLGELTVTDATPDSLSLSWTVPEGQFDQFVIQYKNGDGQPKVVQVPGYEDQVTISGLEPDHKYKMNLYGIHSGQRVGPMSVTGVTAAEEEPLSPTEPSTEAPEPTEEEEPLLGELTVTGSSPDSLSLSWTVPQGHFDSFTVQYKDSNGRPQVVHVGGQEREAIVRDLDPGRKYKMNLYGFHEGRRVGPVSTVGVTAPEEEAPTTQAVPTTTPEPPPKKPLLGELTVTDATPDSLSLSWTVPEGQFDQFVIQYKNGDGQPKVVRVPGYEDQVTISGLEPDHKYKMNLYGIHSGQRVGPVSVIGVTAAEEEPPSPTEPSTEAPEPTEEEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSSGRPQVVRVGGQEREAIVRDLDPGRKYKMNLYGIHSGQRVGPVSAVGVTAAEEEPPSPTEPSTEAPEPTEAPEPTEEEEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSSGRPQVVRVGSQEREAIVTDLDPGRKYKMNLYGFHEGRRVGPVSTVGVTASLTTEPPIQPRLGELAAVEVTPSAVHLSWTVAQGPFDSFLVQYRDAQGQPQMVPVSGDLSEVTVSGLEPSRKYKFLLFGLLGGKRHGPVSTEAKTAALEKTPQPRLGELSVAGETSDSVHLSWTVVQGPFDSFLVQYKDKDGQLQTVPVAADQQEVTIEGLQPGRKYKFLLFGLTGEKRLGPISALGVTASEVDTSTPNPTEHPETPHLGTLAVTEATPNSLRLSWGVARGPFDSFVVQYQDTEGQPQALLVDGNQDKVLISDLKPSTSYKFFLYGLSQGTRHGPVSAEGTTDPVPAGQGPGDPGPRLSQLSVSDVTTSSLRLNWEAPLGSFDSFLLRFGVPLPSTLEPHPRPLLQRELMVPGTRRSAVLRDLRPGTLYSLTLYGLRGPHKADSIQTTARTLSPVLESPRDLQFSDIGETSAKVTWVPPSSRVDSFKISYQLADGGEPQSVQVDGRTHTQILQGLIPDTRYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTDRSALLHWKPPHKPVDKYNVQVASPGAPPLQASAPGSAVDYPLTDLSLDTNYTATVRGLRGPNFTSPASINFTTGLKPPQDLEAKEVTPRTALLTWTAPKVPPTGYLLSFDTPGGQIQEILLPAGTTSHRLLRLFPSTFYSAQLRAIWGESLTPPVSTSFTTGGLRIPFPRDCGEELKNGASASKTTTIFLNGNRERPLDVFCDMQTDGGGWLVFQRRMDGQTDFWRDWEEYAHGFGNISREFWLGNEALHSLTQAGDYSMRVDLRAGKEAVFAQYDFFRVDSAKENYRLHLGGYHGTAGKCGSGWGGGRHEGDPHHAVPRPAGDSMSYHSGSVFSARDRDPNNLLISCAVSYRGAWWYKNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNFQAPTRGT", "length": 4433 }, "evidence": [ { "id": "HGNC:11976", "url": "https://alliancegenome.org/gene/HGNC:11976#orthology", "database": "AGR" }, { "id": "RGD:1594402", "url": "https://alliancegenome.org/gene/RGD:1594402#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9P891-1", "protein_name": "Uncharacterized protein tnxba isoform X1", "gene_name": "tnxba", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNKLGTSTQYKMLISLVFLILNVSFLQGTLSENKNDTIKTIDHTFSHHIPVQVTTPLSTKVKKQTHAASSKMSNSNQTLPFTPKPVVDDIQKSVPLFQDTLSAKDNSTSESRLNAHNVHKPLTRLSNTKIRNQTQSTSSISSSISQTLPSSTEPAVDGVQKPVLALRGKLNEKKHSTVQSTAHLGSLDIPKLVTTKLINKMKNQTRPTLAKPSSVNQTLPSVKKIVADQSTITEKKNSTANLPTQIISVPKTDKKTKNHTQSTFSITSNINQHQDIVEKHPPSLQDPHSQKKNSTMKSPTQTIKVVTTSLNSKKKDQTQSTSLTYSKVNQSLSSSTKPNIHTSQKPMQGVQNKISEKTNSTNKSTVSNVNVQKPATKLNTKLKVQTQYTSSTKTQVNQILTTSTRPEVDSIQNPVQSVQNTISGKKNSTTKSTVNTINVQKPVTSLLKTKLKEQTQSSSSTSQLNQTLTTSQKPGVDSIHKPVQSLQITFGGKTNSTTKSIVNIVDVQKPATKLNTKMKVQTQSTSLTTTQVNLTLPSSTMPEVDSVQKPVQSVQNTISGKKNSTTKSTVNTSNVQKPVTSLLKTKLKEQTQSTPSTSQVKQTLTTSSKPEVDTTQKPVQSVQNTIGDKKNSTTESIVNTINVQNPATRLNTKLKDQTQSTSSTTSKVNHTLPSSTMPDVDTVKKPIQSLQNKIGDKKNSTTKSTVNTINIQKPVTSLLKTKLKEQTQSTPSTSQVNQTLTTSTKPEVNSIQNPVQSVQNTVSDKNNSTTKSTVNTIKVQKPVTSLLKTKLKEKTQSTPSTSQVNQTHTTSTKPEVESIQNPVQSVQDTISGKKNSTTKSTVNTINVQKPVTSLLKTKLKEQTQSTPSTSQVNQTLTSSIKPEVDSIQKPVQSAKNTIGDQTNSTTKSTVNIINVKKPVTTLLKNKQKERTQSISSTTSQVNQTLPASTKSDVDSIQKPVQSVQTTINDKKNSTTKSTDNHIIVQKPVGTLLKNKMRIQALSNSTKNSIIDQTSLSAKPAVDVVQKSVSPSPTTFGEKRNTTTKLVSHNINVNASKPENTKVQTQSVSSKPTHINQTLLSTPKPAVDVKTPGSALQDISGTKKNSTSKLTAQTIRNNVPTLTTLLNIKLKNQTHPSFSTISHVNQTVPFSTKFVDEVTHRMKKNSTVKARLQTININASKPVTTSLHTKTKNQTQSTSLKISKANQTSPSTTKPVEGEISLGKKKNFTVKSASQSIDVHASKPITTPPNTKTKNQTKPSSSKNNNNDQAVTSTSPVMDGTQNLDIDKLAESSPIKIVITEGCVQRKSQGDVGNITKIRETELSLNPGSPLVMTHRINLVQGTCNGGCETDMAALRERIELLEKEMSAIKQMCVPCSGEQCPKNCSGQGKCEEGKCVCFQGFSGPDCSSKACPSNCNKKGKCVKGKCVCQTGFTGIGCSKAIDERITVTVETVTMKMSSAMPDTKTVKTRPDKAILVKETVTKVPKKHTTAKPTVKPSPTASTDKVLSHTTGKDNIKIVGQQSESMKLQEQTKGKTTVIKMGSDNQAQTDLSDKSHNAKDEPAYQNVTQRSVKKSNGTSKILHNLFKGSMNVTRSKTKITTRTAGDQGEESKTNAVSAEKDEKLFHGNVTTVQAEKKSDKPEIDASVESKAHMKHFSKTSSRLSVIGSVEVHNITSTGFIMSWEAHRDKFKNFTVTRREIKAGNEDSEKIHEAIENVTDAERLGSNRTLTKILSSKSEGNAMKKFSQILAGTTRSYHFKGLQPQTQYAISLFGSGPGMRSKIHRITLSTGPEPPTDLVFSNITETSFSLSWAKPKSIVAEFKVKYINTVTGESGSMSVDSQLSHVLLSKLTAGTTYDITVSSVLDKLESEPVIASITTVPDSPTELKVVNITDTKALLVWKPSKAKVDSYILSYGTTKSPNVTITVTLSGSSVEHQLRALHRSSLYMVKMTSQVNRLQSSSVSTSFTTGSGVKLQVVTPDEVTFHSAVISWKAPRVAFKSYRLTYQLSEEVKELILNPSVTHYELTGLAAFSNYTVKIDGERDGQYISFVSSDFTTAQLPHPYPTDCSEVQINGMKESGEAEIYPEGKNGEPVRVYCDMETDGGAWTVFQRRMDGSTDFFRSWRDYSKGFGLLSGEFWLGNDVLHTLTSLKAMSLRIDLRSGNDTAFAQYINFNISSEANHYAIDLSGYSGTAGDSMKYHKGRPFSTKDKDPDTLSIHCAKAYMGGWWYKNCYKANLNGLYASYSDNKGVVWIDWKGKDASLPFTEMKLRPSNFSQTTSTTPTAQS", "length": 2285 }, "evidence": [ { "id": "MGI:1932137", "url": "https://alliancegenome.org/gene/MGI:1932137#orthology", "database": "AGR" }, { "id": "HGNC:11976", "url": "https://alliancegenome.org/gene/HGNC:11976#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070103-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070103-5#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q16473-1", "protein_name": "Putative tenascin-XA", "gene_name": "TNXA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDKNGAPHGAPHSDSPLGFSHAAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGRARTQKLQFLTVPHSCVH", "length": 311 }, "evidence": [ { "id": "MGI:1932137", "url": "https://alliancegenome.org/gene/MGI:1932137#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "integrin binding", "id": "GO:0005178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005178", "evidence": [ { "database": "UniProtKB", "id": "P22105", "url": "https://www.uniprot.org/uniprotkb/P22105" } ], "pmid": "" }, { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "P22105", "url": "https://www.uniprot.org/uniprotkb/P22105" } ], "pmid": "" }, { "name": "collagen binding", "id": "GO:0005518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005518", "evidence": [ { "database": "UniProtKB", "id": "P22105", "url": "https://www.uniprot.org/uniprotkb/P22105" } ], "pmid": "" }, { "name": "extracellular matrix structural constituent", "id": "GO:0005201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005201", "evidence": [ { "database": "UniProtKB", "id": "P22105", "url": "https://www.uniprot.org/uniprotkb/P22105" } ], "pmid": "" }, { "name": "collagen fibril binding", "id": "GO:0098633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098633", "evidence": [ { "database": "UniProtKB", "id": "P22105", "url": "https://www.uniprot.org/uniprotkb/P22105" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P22105", "url": "https://www.uniprot.org/uniprotkb/P22105" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "P22105", "url": "https://www.uniprot.org/uniprotkb/P22105" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "P22105", "url": "https://www.uniprot.org/uniprotkb/P22105" } ], "pmid": "" }, { "name": "extracellular exosome", "id": "GO:0070062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070062", "evidence": [ { "database": "UniProtKB", "id": "P22105", "url": "https://www.uniprot.org/uniprotkb/P22105" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "P22105", "url": "https://www.uniprot.org/uniprotkb/P22105" } ], "pmid": "" }, { "name": "regulation of cell adhesion", "id": "GO:0030155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030155", "evidence": [ { "database": "UniProtKB", "id": "P22105", "url": "https://www.uniprot.org/uniprotkb/P22105" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "P22105", "url": "https://www.uniprot.org/uniprotkb/P22105" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "P22105", "url": "https://www.uniprot.org/uniprotkb/P22105" } ], "pmid": "" }, { "name": "regulation of cell differentiation", "id": "GO:0045595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045595", "evidence": [ { "database": "UniProtKB", "id": "P22105", "url": "https://www.uniprot.org/uniprotkb/P22105" } ], "pmid": "" }, { "name": "elastic fiber assembly", "id": "GO:0048251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048251", "evidence": [ { "database": "UniProtKB", "id": "P22105", "url": "https://www.uniprot.org/uniprotkb/P22105" } ], "pmid": "" }, { "name": "positive regulation of collagen fibril organization", "id": "GO:1904028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904028", "evidence": [ { "database": "UniProtKB", "id": "P22105", "url": "https://www.uniprot.org/uniprotkb/P22105" } ], "pmid": "" }, { "name": "collagen metabolic process", "id": "GO:0032963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032963", "evidence": [ { "database": "UniProtKB", "id": "P22105", "url": "https://www.uniprot.org/uniprotkb/P22105" } ], "pmid": "" }, { "name": "positive regulation of cell fate determination", "id": "GO:1905935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905935", "evidence": [ { "database": "UniProtKB", "id": "P22105", "url": "https://www.uniprot.org/uniprotkb/P22105" } ], "pmid": "" } ] } ] }, "pro_annotation": [ { "name": "tenascin-X O-glycosylated 1 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Ser-178 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Ser-178, MOD:00002~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056146", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056146" } ] }, { "name": "tenascin-X O-glycosylated 2 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Ser-178 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P22105-3, Ser-178, MOD:00002~GNO:G53434XO. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056147", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056147" } ] }, { "name": "tenascin-X O-glycosylated 3 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Ser-2292 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P22105-3, Ser-2292, MOD:00002~GNO:G53434XO. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056148", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056148" } ] }, { "name": "tenascin-X O-glycosylated 4 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Ser-2943 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P22105-3, Ser-2943, MOD:00002~GNO:G53434XO. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056149", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056149" } ] }, { "name": "tenascin-X O-glycosylated 5 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Ser-3923 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Ser-3923, MOD:00002~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056150", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056150" } ] }, { "name": "tenascin-X O-glycosylated 6 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Ser-54 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Ser-54, MOD:00002~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056151", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056151" } ] }, { "name": "tenascin-X O-glycosylated 7 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Ser-943 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Ser-943, MOD:00002~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056152", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056152" } ] }, { "name": "tenascin-X O-glycosylated 8 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Ser-946 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P22105-3, Ser-946, MOD:00002~GNO:G53434XO. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056153", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056153" } ] }, { "name": "tenascin-X O-glycosylated 9 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Ser-946 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G73004SD. Example: UniProtKB:P22105-3, Ser-946, MOD:00002~GNO:G73004SD. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056154", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056154" } ] }, { "name": "tenascin-X O-glycosylated 10 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-1180 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Thr-1180, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056155", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056155" } ] }, { "name": "tenascin-X O-glycosylated 11 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-1364 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Thr-1364, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056156", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056156" } ] }, { "name": "tenascin-X O-glycosylated 12 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-1469 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P22105-3, Thr-1469, MOD:00005~GNO:G29068FM. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056157", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056157" } ] }, { "name": "tenascin-X O-glycosylated 13 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-1469 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Thr-1469, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056158", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056158" } ] }, { "name": "tenascin-X O-glycosylated 14 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-1569 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P22105-3, Thr-1569, MOD:00005~GNO:G29068FM. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056159", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056159" } ] }, { "name": "tenascin-X O-glycosylated 15 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-1569 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Thr-1569, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056160", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056160" } ] }, { "name": "tenascin-X O-glycosylated 16 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-1872 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P22105-3, Thr-1872, MOD:00005~GNO:G53434XO. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056161", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056161" } ] }, { "name": "tenascin-X O-glycosylated 17 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-1873 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Thr-1873, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056162", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056162" } ] }, { "name": "tenascin-X O-glycosylated 18 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-1876 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Thr-1876, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056163", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056163" } ] }, { "name": "tenascin-X O-glycosylated 19 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-2083 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Thr-2083, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056164", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056164" } ] }, { "name": "tenascin-X O-glycosylated 20 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-2324 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P22105-3, Thr-2324, MOD:00005~GNO:G29068FM. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056165", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056165" } ] }, { "name": "tenascin-X O-glycosylated 21 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-2324 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Thr-2324, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056166", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056166" } ] }, { "name": "tenascin-X O-glycosylated 22 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-2357 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Thr-2357, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056167", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056167" } ] }, { "name": "tenascin-X O-glycosylated 23 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-2399 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Thr-2399, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056168", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056168" } ] }, { "name": "tenascin-X O-glycosylated 24 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-2514 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Thr-2514, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056169", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056169" } ] }, { "name": "tenascin-X O-glycosylated 25 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-2649 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Thr-2649, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056170", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056170" } ] }, { "name": "tenascin-X O-glycosylated 26 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-2837 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:P22105-3, Thr-2837, MOD:00005~GNO:G58001LT. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056171", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056171" } ] }, { "name": "tenascin-X O-glycosylated 27 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-2838 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P22105-3, Thr-2838, MOD:00005~GNO:G29068FM. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056172", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056172" } ] }, { "name": "tenascin-X O-glycosylated 28 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-2838 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Thr-2838, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056173", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056173" } ] }, { "name": "tenascin-X O-glycosylated 29 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-2944 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Thr-2944, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056174", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056174" } ] }, { "name": "tenascin-X O-glycosylated 30 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-3052 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Thr-3052, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056175", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056175" } ] }, { "name": "tenascin-X O-glycosylated 31 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-3054 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P22105-3, Thr-3054, MOD:00005~GNO:G29068FM. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056176", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056176" } ] }, { "name": "tenascin-X O-glycosylated 32 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-3054 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Thr-3054, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056177", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056177" } ] }, { "name": "tenascin-X O-glycosylated 33 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-3158 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Thr-3158, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056178", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056178" } ] }, { "name": "tenascin-X O-glycosylated 34 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-3257 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Thr-3257, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056179", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056179" } ] }, { "name": "tenascin-X O-glycosylated 35 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-3541 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P22105-3, Thr-3541, MOD:00005~GNO:G29068FM. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056180", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056180" } ] }, { "name": "tenascin-X O-glycosylated 36 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-3541 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Thr-3541, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056181", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056181" } ] }, { "name": "tenascin-X O-glycosylated 37 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-3880 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Thr-3880, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056182", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056182" } ] }, { "name": "tenascin-X O-glycosylated 38 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-3922 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P22105-3, Thr-3922, MOD:00005~GNO:G53434XO. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056183", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056183" } ] }, { "name": "tenascin-X O-glycosylated 39 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-47 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Thr-47, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056184", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056184" } ] }, { "name": "tenascin-X O-glycosylated 40 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-83 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Thr-83, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056185", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056185" } ] }, { "name": "tenascin-X O-glycosylated 41 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-91 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P22105-3, Thr-91, MOD:00005~GNO:G29068FM. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056186", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056186" } ] }, { "name": "tenascin-X O-glycosylated 42 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-91 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Thr-91, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056187", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056187" } ] }, { "name": "tenascin-X O-glycosylated 43 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-936 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P22105-3, Thr-936, MOD:00005~GNO:G53434XO. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056188", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056188" } ] }, { "name": "tenascin-X O-glycosylated 44 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-937 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G35029YA. Example: UniProtKB:P22105-3, Thr-937, MOD:00005~GNO:G35029YA. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056189", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056189" } ] }, { "name": "tenascin-X O-glycosylated 45 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-937 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Thr-937, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056190", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056190" } ] }, { "name": "tenascin-X O-glycosylated 46 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-937 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P22105-3, Thr-937, MOD:00005~GNO:G53434XO. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056191", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056191" } ] }, { "name": "tenascin-X O-glycosylated 47 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-947 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Thr-947, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056192", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056192" } ] }, { "name": "tenascin-X O-glycosylated 48 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-947 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P22105-3, Thr-947, MOD:00005~GNO:G53434XO. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056193", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056193" } ] }, { "name": "tenascin-X O-glycosylated 49 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-948 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P22105-3, Thr-948, MOD:00005~GNO:G29068FM. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056194", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056194" } ] }, { "name": "tenascin-X O-glycosylated 50 (human)", "definition": "A tenascin-X (human) that has been O-glycosylated at the residue equivalent to Thr-948 of the amino acid sequence represented by UniProtKB:P22105-3, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22105-3, Thr-948, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000056195", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000056195" } ] } ], "site_annotation": [ { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3855, "end_pos": 3857, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3908, "end_pos": 3910, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3920, "end_pos": 3922, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4095, "end_pos": 4097, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "2cuh", "pdb_chain": "a", "start_pos": 3845, "end_pos": 3946, "overlap": "1.0", "method": "NMR_Spectroscopy", "type": "experimental", "resolution": 100.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/2cuh.pdb", "url_external": "https://www.rcsb.org/structure/2cuh" }, { "pdb_id": "2cui", "pdb_chain": "a", "start_pos": 3654, "end_pos": 3752, "overlap": "1.0", "method": "NMR_Spectroscopy", "type": "experimental", "resolution": 100.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/2cui.pdb", "url_external": "https://www.rcsb.org/structure/2cui" }, { "pdb_id": "2cum", "pdb_chain": "a", "start_pos": 3933, "end_pos": 4024, "overlap": "1.0", "method": "NMR_Spectroscopy", "type": "experimental", "resolution": 100.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/2cum.pdb", "url_external": "https://www.rcsb.org/structure/2cum" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "P22105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22105" } ], "ann_type": "Motif_Annotation", "uniprotkb_annotation": "Cell attachment site", "eco_id": "ECO_0000255", "start_pos": 1666, "end_pos": 1668, "start_aa": "Arg", "end_aa": "Asp", "glycosite_overlap": [] }, { "evidence": [ { "id": "P22105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22105" }, { "id": "PRU00076", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like 10", "eco_id": "ECO_0000255", "start_pos": 431, "end_pos": 461, "start_aa": "Gly", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "P22105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22105" }, { "id": "PRU00076", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like 11", "eco_id": "ECO_0000255", "start_pos": 462, "end_pos": 492, "start_aa": "Gly", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "P22105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22105" }, { "id": "PRU00076", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like 12", "eco_id": "ECO_0000255", "start_pos": 493, "end_pos": 523, "start_aa": "Gly", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "P22105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22105" }, { "id": "PRU00076", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like 13", "eco_id": "ECO_0000255", "start_pos": 524, "end_pos": 554, "start_aa": "Gly", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "P22105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22105" }, { "id": "PRU00076", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like 14", "eco_id": "ECO_0000255", "start_pos": 555, "end_pos": 585, "start_aa": "Ser", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "P22105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22105" }, { "id": "PRU00076", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like 15", "eco_id": "ECO_0000255", "start_pos": 586, "end_pos": 616, "start_aa": "Gly", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "P22105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22105" }, { "id": "PRU00076", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like 16", "eco_id": "ECO_0000255", "start_pos": 617, "end_pos": 647, "start_aa": "Ser", "end_aa": "Cys", "glycosite_overlap": [ { "position": 643, "amino_acid": "Thr" } ] }, { "evidence": [ { "id": "P22105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22105" }, { "id": "PRU00076", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like 17", "eco_id": "ECO_0000255", "start_pos": 648, "end_pos": 679, "start_aa": "Ala", "end_aa": "Gly", "glycosite_overlap": [] }, { "evidence": [ { "id": "P22105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22105" }, { "id": "PRU00076", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like 18", "eco_id": "ECO_0000255", "start_pos": 684, "end_pos": 714, "start_aa": "Pro", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "P22105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22105" }, { "id": "PRU00076", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like 19", "eco_id": "ECO_0000255", "start_pos": 715, "end_pos": 746, "start_aa": "Ala", "end_aa": "Gly", "glycosite_overlap": [] }, { "evidence": [ { "id": "P22105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22105" }, { "id": "PRU00076", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like 1; incomplete", "eco_id": "ECO_0000255", "start_pos": 156, "end_pos": 168, "start_aa": "Cys", "end_aa": "Ser", "glycosite_overlap": [] }, { "evidence": [ { "id": "P22105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22105" }, { "id": "PRU00076", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like 2", "eco_id": "ECO_0000255", "start_pos": 183, "end_pos": 213, "start_aa": "Ala", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "P22105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22105" }, { "id": "PRU00076", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like 3", "eco_id": "ECO_0000255", "start_pos": 214, "end_pos": 244, "start_aa": "Gly", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "P22105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22105" }, { "id": "PRU00076", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like 4", "eco_id": "ECO_0000255", "start_pos": 245, "end_pos": 275, "start_aa": "Ser", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "P22105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22105" }, { "id": "PRU00076", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like 5", "eco_id": "ECO_0000255", "start_pos": 276, "end_pos": 306, "start_aa": "Gly", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "P22105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22105" }, { "id": "PRU00076", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like 6", "eco_id": "ECO_0000255", "start_pos": 307, "end_pos": 337, "start_aa": "Gly", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "P22105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22105" }, { "id": "PRU00076", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like 7", "eco_id": "ECO_0000255", "start_pos": 338, "end_pos": 368, "start_aa": "Gly", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": 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