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        "ec_number_list": [],
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        "go_cellular_component": "GO:0005615 extracellular space",
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        "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9VZ35-1",
        "uniprot_id": [
            {
                "id": "VAGO_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VZ35",
                "type": "external"
            }
        ],
        "mass": 18148.0,
        "length": 160,
        "protein_name": "Protein Vago",
        "gene_name": "Vago",
        "organism": "Fruit fly",
        "refseq_name": "vago, isoform D",
        "refseq_ac": [
            {
                "id": "NP_001285106",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285106",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Vago; CG2081; DIGF-2",
        "gene_names_refseq": "BcDNA:RH70969; CG2081; DIGF-2; Dmel\\CG2081; VAGO; Vago; vago",
        "protein_names_uniprotkb": "Protein Vago",
        "protein_names_refseq": "CG2081-PD; Vago-PD; vago, isoform D",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG2081)",
        "pathway_count": 1,
        "publication_count": 4,
        "publication_id_list": "10731132;12537569;12537572;18953338",
        "class_list": "",
        "function": "Probably involved in the antiviral immune response (PubMed:18953338). May have a role in controlling viral load in the adult fat body, after infection with viruses such as the Drosophila C virus (PubMed:18953338)., [UniProtKB, PubMed]",
        "predicted_glycosites": 0,
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        "secondary_ac_list": "D2NUJ3;Q8MYS7",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005615 extracellular space",
        "go_biological_process": "GO:0051607 defense response to virus",
        "synthesized_glycan_count": 0,
        "hit_score": 0.5,
        "record_id": "Q9VZ35-1",
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        "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9VZ44-1",
        "uniprot_id": [
            {
                "id": "Q9VZ44_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VZ44",
                "type": "external"
            }
        ],
        "mass": 60027.0,
        "length": 559,
        "protein_name": "Delta-like protein",
        "gene_name": "C901",
        "organism": "Fruit fly",
        "refseq_name": "C901",
        "refseq_ac": [
            {
                "id": "NP_572673",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572673",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "C901; 10; CG1567; CT4052; Dmel\\CG1567; Dmel_CG1567; anon-10Ab; c901; cDNA 901",
        "gene_names_refseq": "10; C901; CG1567; CT4052; Dmel\\CG1567; anon-10Ab; c901; cDNA 901",
        "protein_names_uniprotkb": "Delta-like protein",
        "protein_names_refseq": "C901-PA; C901; CG1567-PA",
        "tax_id": 7227,
        "disease": "ductal carcinoma in situ (Disease Ontology:DOID:0060074); dementia (Disease Ontology:DOID:1307); endometrial cancer (Disease Ontology:DOID:1380); arteriosclerosis (Disease Ontology:DOID:2349); multiple sclerosis (Disease Ontology:DOID:2377); hemangiopericytoma (Disease Ontology:DOID:264); systemic scleroderma (Disease Ontology:DOID:418); hemangioblastoma (Disease Ontology:DOID:5241); schizophrenia (Disease Ontology:DOID:5419); rheumatoid arthritis (Disease Ontology:DOID:7148); type 1 diabetes mellitus (Disease Ontology:DOID:9744); alopecia areata (Disease Ontology:DOID:986)",
        "pathway": " (dme:Dmel_CG1567);  (R-DME-2979096)",
        "pathway_count": 2,
        "publication_count": 11,
        "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357",
        "class_list": "",
        "function": "Putative Notch ligand involved in the mediation of Notch signaling., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005112 Notch binding",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0048731 system development;GO:0007219 Notch signaling pathway;GO:0045746 negative regulation of Notch signaling pathway;GO:0048513 animal organ development",
        "synthesized_glycan_count": 0,
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        "record_id": "Q9VZ44-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000100000000000.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9VZ61-1",
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            {
                "id": "Q9VZ61_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VZ61",
                "type": "external"
            }
        ],
        "mass": 71067.0,
        "length": 607,
        "protein_name": "Sister of feo, isoform A; Sister of feo, isoform B",
        "gene_name": "sofe",
        "organism": "Fruit fly",
        "refseq_name": "sister of feo, isoform B",
        "refseq_ac": [
            {
                "id": "NP_001285092",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285092",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "sofe; CG1655; Dmel\\CG1655; Dmel_CG1655",
        "gene_names_refseq": "CG1655; Dmel\\CG1655; sofe",
        "protein_names_uniprotkb": "Sister of feo, isoform A; Sister of feo, isoform B",
        "protein_names_refseq": "CG1655-PB; sister of feo, isoform B; sofe-PB",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG1655)",
        "pathway_count": 1,
        "publication_count": 11,
        "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357",
        "class_list": "",
        "function": "",
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        "go_molecular_function": "GO:0008017 microtubule binding",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005819 spindle;GO:1990023 mitotic spindle midzone",
        "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0000226 microtubule cytoskeleton organization;GO:0051256 mitotic spindle midzone assembly",
        "synthesized_glycan_count": 0,
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    },
    {
        "uniprot_canonical_ac": "Q9VZ73-1",
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            {
                "id": "Q9VZ73_DROME",
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                "type": "external"
            }
        ],
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        "length": 180,
        "protein_name": "Ubiquitin-conjugating enzyme E2-18 kDa",
        "gene_name": "Dmel\\CG17030",
        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "NP_647941",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647941",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Dmel\\CG17030; CG17030; Dmel_CG17030",
        "gene_names_refseq": "CG17030; Dmel\\CG17030",
        "protein_names_uniprotkb": "Ubiquitin-conjugating enzyme E2-18 kDa; 2.3.2.23",
        "protein_names_refseq": "CG17030-PA; uncharacterized protein",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG17030);  (R-DME-983168)",
        "pathway_count": 2,
        "publication_count": 11,
        "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357",
        "class_list": "",
        "function": "",
        "predicted_glycosites": 0,
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        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": [
            {
                "id": "2.3.2.27",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27",
                "type": "external"
            },
            {
                "id": "2.3.2.25",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25",
                "type": "external"
            },
            {
                "id": "2.3.2.23",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23",
                "type": "external"
            },
            {
                "id": "2.3.2.31",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31",
                "type": "external"
            },
            {
                "id": "6.2.1.64",
                "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.64",
                "type": "external"
            },
            {
                "id": "2.3.2.26",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26",
                "type": "external"
            },
            {
                "id": "2.3.2.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-",
                "type": "external"
            },
            {
                "id": "2.3.2.34",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34",
                "type": "external"
            },
            {
                "id": "2.3.2.24",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.24",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0004842 ubiquitin-protein transferase activity;GO:0061631 ubiquitin conjugating enzyme activity",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0000209 protein polyubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process",
        "synthesized_glycan_count": 0,
        "hit_score": 1.2,
        "record_id": "Q9VZ73-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9VZ81-1",
        "uniprot_id": [
            {
                "id": "Q9VZ81_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VZ81",
                "type": "external"
            }
        ],
        "mass": 140279.0,
        "length": 1301,
        "protein_name": "Dynein axonemal assembly factor 1 homolog",
        "gene_name": "CT33170",
        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein, isoform B",
        "refseq_ac": [
            {
                "id": "NP_001261433",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261433",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "CT33170; CG13708; Dmel\\CG13708; Dmel_CG13708",
        "gene_names_refseq": "CG13708; CT33170; Dmel\\CG13708",
        "protein_names_uniprotkb": "Dynein axonemal assembly factor 1 homolog; Defective transmitter-recycling protein; Leucine-rich repeat-containing protein 50 homolog",
        "protein_names_refseq": "CG13708-PB; uncharacterized protein, isoform B",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG13708)",
        "pathway_count": 1,
        "publication_count": 11,
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        "class_list": "",
        "function": "Cilium-specific protein required for cilia structures., [UniProtKB, UniProtKB]",
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        "biomarker_type": "",
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        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
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        "record_id": "Q9VZ81-1",
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        "filter_code": "0000000.0000101.010000.000000100000000000.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9VZ82-1",
        "uniprot_id": [
            {
                "id": "Q9VZ82_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VZ82",
                "type": "external"
            }
        ],
        "mass": 99300.0,
        "length": 869,
        "protein_name": "leucine--tRNA ligase",
        "gene_name": "LeuRS-m",
        "organism": "Fruit fly",
        "refseq_name": "Leucyl-tRNA synthetase, mitochondrial",
        "refseq_ac": [
            {
                "id": "NP_647932",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647932",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LeuRS-m; Aats-leu; CG7479; Dmel\\CG7479; Dmel_CG7479; LARS; LRS; LeuRS; dLARS",
        "gene_names_refseq": "Aats-leu; CG7479; Dmel\\CG7479; LARS; LRS; LeuRS-m; LeuRS; dLARS",
        "protein_names_uniprotkb": "leucine--tRNA ligase; 6.1.1.4; Leucyl-tRNA synthetase",
        "protein_names_refseq": "CG7479-PA; LeuRS-m-PA; Leucyl-tRNA synthetase, mitochondrial; Leucyl-tRNA synthetase; mitochondrial leucyl-tRNA synthetase",
        "tax_id": 7227,
        "disease": "Perrault syndrome (Disease Ontology:DOID:0050857); mitochondrial metabolism disease (Disease Ontology:DOID:700)",
        "pathway": " (dme:Dmel_CG7479)",
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            {
                "id": "6.1.1.4",
                "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.4",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0002161 aminoacyl-tRNA deacylase activity;GO:0004823 leucine-tRNA ligase activity;GO:0005524 ATP binding",
        "go_cellular_component": "GO:0005739 mitochondrion",
        "go_biological_process": "GO:0006429 leucyl-tRNA aminoacylation;GO:0032543 mitochondrial translation",
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        "hit_score": 1.2,
        "record_id": "Q9VZ82-1",
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    },
    {
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            {
                "id": "Q9VZ85_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VZ85",
                "type": "external"
            }
        ],
        "mass": 214913.0,
        "length": 1984,
        "protein_name": "Rho guanine nucleotide exchange factor at 64C, isoform A; Rho guanine nucleotide exchange factor at 64C, isoform B",
        "gene_name": "RhoGEF64C",
        "organism": "Fruit fly",
        "refseq_name": "Rho guanine nucleotide exchange factor at 64C, isoform B",
        "refseq_ac": [
            {
                "id": "NP_001261425",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261425",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "RhoGEF64C; CG13709; CG13710; CG32239; Dmel\\CG32239; Dmel_CG32239; EP(3)3035; EP3035; GEF(64C); GEF64C; GEF; Gef64C; RhoGEF64; RhoGEF; RhoGef64C",
        "gene_names_refseq": "CG13709; CG13710; CG32239; Dmel\\CG32239; EP(3)3035; EP3035; GEF(64C); GEF64C; GEF; Gef64C; RhoGEF64C; RhoGEF64; RhoGEF; RhoGef64C",
        "protein_names_uniprotkb": "Rho guanine nucleotide exchange factor at 64C, isoform A; Rho guanine nucleotide exchange factor at 64C, isoform B",
        "protein_names_refseq": "CG32239-PB; Rho guanine nucleotide exchange factor at 64C, isoform B; Rho guanine nucleotide exchange factor; RhoGEF64C-PB; guanine nucleotide exchange factor 64C; guanine nucleotide exchange factor GEF64C; guanine nucleotide exchange factor",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG32239)",
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        "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity",
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        "go_biological_process": "GO:0035025 positive regulation of Rho protein signal transduction;GO:0007411 axon guidance;GO:0007480 imaginal disc-derived leg morphogenesis;GO:0035277 spiracle morphogenesis, open tracheal system",
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    },
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        "uniprot_canonical_ac": "Q9VZ97-1",
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            {
                "id": "Q9VZ97_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VZ97",
                "type": "external"
            }
        ],
        "mass": 55038.0,
        "length": 487,
        "protein_name": "Polyglutamylase complex subunit TTLL1",
        "gene_name": "TTLL1B",
        "organism": "Fruit fly",
        "refseq_name": "tubulin tyrosine ligase-like 1B",
        "refseq_ac": [
            {
                "id": "NP_729025",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_729025",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "TTLL1B; CG32238; CG7474; DmCG32238; Dmel\\CG32238; Dmel_CG32238; TTLL1",
        "gene_names_refseq": "CG32238; CG7474; DmCG32238; Dmel\\CG32238; TTLL1B; TTLL1",
        "protein_names_uniprotkb": "Polyglutamylase complex subunit TTLL1; Tubulin polyglutamylase TTLL1; Tubulin polyglutamylase complex subunit 3; Tubulin--tyrosine ligase-like protein 1",
        "protein_names_refseq": "CG32238-PA; TTLL1B-PA; tubulin tyrosine ligase-like 1B",
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        "disease": "primary ciliary dyskinesia (Disease Ontology:DOID:9562)",
        "pathway": " (dme:Dmel_CG32238)",
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        "go_molecular_function": "GO:0070740 tubulin-glutamic acid ligase activity;GO:0005524 ATP binding;GO:0015631 tubulin binding",
        "go_cellular_component": "GO:0005874 microtubule;GO:0036064 ciliary basal body",
        "go_biological_process": "GO:0007288 sperm axoneme assembly",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9VZE9-1",
        "uniprot_id": [
            {
                "id": "Q9VZE9_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VZE9",
                "type": "external"
            }
        ],
        "mass": 9387.0,
        "length": 85,
        "protein_name": "V-type proton ATPase subunit",
        "gene_name": "VhaM9.7-a",
        "organism": "Fruit fly",
        "refseq_name": "vacuolar H[+] ATPase M9.7 subunit a, isoform B",
        "refseq_ac": [
            {
                "id": "NP_001097499",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097499",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "VhaM9.7-a; CG1268; Dmel\\CG1268; Dmel_CG1268; VhaM9.7-1; vhaM9.7-1",
        "gene_names_refseq": "CG1268; Dmel\\CG1268; VhaM9.7-1; VhaM9.7-a; vhaM9.7-1",
        "protein_names_uniprotkb": "V-type proton ATPase subunit",
        "protein_names_refseq": "CG1268-PB; VhaM9.7-a-PB; vacuolar H[+] ATPase M9.7 subunit a, isoform B; vacuolar H[+] ATPase subunit M9.7-a",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG1268);  (R-DME-1222556);  (R-DME-77387);  (R-DME-917977);  (R-DME-9639288);  (R-DME-983712)",
        "pathway_count": 6,
        "publication_count": 11,
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        "class_list": "",
        "function": "Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment., [UniProtKB, UniProtKB]",
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        "ec_number_list": [],
        "go_molecular_function": "GO:0046961 proton-transporting ATPase activity, rotational mechanism",
        "go_cellular_component": "GO:0012505 endomembrane system;GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain",
        "go_biological_process": "GO:1902600 proton transmembrane transport",
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        "hit_score": 1.2,
        "record_id": "Q9VZE9-1",
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        "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9VZF0-1",
        "uniprot_id": [
            {
                "id": "Q9VZF0_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VZF0",
                "type": "external"
            }
        ],
        "mass": 22938.0,
        "length": 194,
        "protein_name": "U1-type domain-containing protein",
        "gene_name": "Dmel\\CG11586",
        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein, isoform B",
        "refseq_ac": [
            {
                "id": "NP_001261410",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261410",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Dmel\\CG11586; CG11586; Dmel_CG11586",
        "gene_names_refseq": "CG11586; Dmel\\CG11586",
        "protein_names_uniprotkb": "U1-type domain-containing protein",
        "protein_names_refseq": "CG11586-PB; uncharacterized protein, isoform B",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG11586)",
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        "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding",
        "go_cellular_component": "GO:0005681 spliceosomal complex;GO:0046540 U4/U6 x U5 tri-snRNP complex",
        "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome",
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    },
    {
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            {
                "id": "Q9VZG2_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VZG2",
                "type": "external"
            }
        ],
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        "length": 192,
        "protein_name": "Cuticular protein 64Aa",
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        "organism": "Fruit fly",
        "refseq_name": "cuticular protein 64Aa",
        "refseq_ac": [
            {
                "id": "NP_647872",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647872",
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            }
        ],
        "gene_names_uniprotkb": "Cpr64Aa; CG15006; DmelCpr64Aa; Dmel\\CG15006; Dmel_CG15006",
        "gene_names_refseq": "CG15006; Cpr64Aa; DmelCpr64Aa; Dmel\\CG15006",
        "protein_names_uniprotkb": "Cuticular protein 64Aa",
        "protein_names_refseq": "CG15006-PA; Cpr64Aa-PA; cuticular protein 64Aa",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG15006)",
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        "go_molecular_function": "GO:0008010 structural constituent of chitin-based larval cuticle",
        "go_cellular_component": "GO:0031012 extracellular matrix;GO:0062129 chitin-based extracellular matrix",
        "go_biological_process": "GO:0040003 chitin-based cuticle development",
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    },
    {
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            {
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                "type": "external"
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        ],
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        "length": 448,
        "protein_name": "TipE homolog 3",
        "gene_name": "Teh3",
        "organism": "Fruit fly",
        "refseq_name": "tipE homolog 3",
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                "id": "NP_652335",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_652335",
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            }
        ],
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        "protein_names_refseq": "ASCIZ homolog; ASCIZ zinc finger protein, isoform B; Asciz-PB; CG14962-PB",
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        ],
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        ],
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        "protein_names_refseq": "CG1228-PI; Meg; Ptpmeg-PI; protein tyrosine phosphatase Meg, isoform I; split central complex",
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                "id": "2.7.11.24",
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                "id": "2.7.10.1",
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                "id": "3.1.3.-",
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                "id": "2.3.2.27",
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        ],
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        "go_biological_process": "GO:0009887 animal organ morphogenesis;GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway;GO:0040040 thermosensory behavior;GO:0048846 axon extension involved in axon guidance;GO:0016319 mushroom body development",
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        ],
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                "id": "1.-.-.-",
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        ],
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            {
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        "protein_names_uniprotkb": "ceramide glucosyltransferase; 2.4.1.80",
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        "disease": "hypertension (Disease Ontology:DOID:10763)",
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        ],
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        "refseq_name": "uncharacterized protein",
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            {
                "id": "NP_611633",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611633",
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        ],
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        "protein_names_refseq": "CG11475-PA; uncharacterized protein",
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        "function": "Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism. Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues. Possibly methylates PCNA, suggesting it is involved in the DNA damage response., [UniProtKB, UniProtKB, UniProtKB]",
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                "id": "NP_788420",
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        ],
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                "id": "Q9W3V7_DROME",
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            }
        ],
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        "refseq_name": "ataxin 1",
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            {
                "id": "NP_572356",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572356",
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            }
        ],
        "gene_names_uniprotkb": "Atx-1; CG4547; Dmel\\CG4547; Dmel_CG4547; dAtx-1",
        "gene_names_refseq": "Atx-1; CG4547; Dmel\\CG4547; dAtx-1",
        "protein_names_uniprotkb": "Ataxin 1",
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        "tax_id": 7227,
        "disease": "spinocerebellar ataxia 1 (Disease Ontology:DOID:0050954); autosomal dominant cerebellar ataxia (Disease Ontology:DOID:1441)",
        "pathway": " (dme:Dmel_CG4547)",
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        "ec_number_list": [],
        "go_molecular_function": "GO:0003677 DNA binding;GO:0003723 RNA binding",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0045494 photoreceptor cell maintenance;GO:0007474 imaginal disc-derived wing vein specification",
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            {
                "id": "Q9W3W4_DROME",
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        ],
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        "length": 219,
        "protein_name": "5-demethoxyubiquinone hydroxylase, mitochondrial",
        "gene_name": "Coq7",
        "organism": "Fruit fly",
        "refseq_name": "coenzyme Q7",
        "refseq_ac": [
            {
                "id": "NP_651967",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_651967",
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            }
        ],
        "gene_names_uniprotkb": "Coq7; CG14437; COQ7; Dclk1; Dmel\\CG14437; Dmel_CG14437",
        "gene_names_refseq": "CG14437; COQ7; Coq7; Dclk1; Dmel\\CG14437",
        "protein_names_uniprotkb": "5-demethoxyubiquinone hydroxylase, mitochondrial; 1.14.99.60; DMQ hydroxylase; Ubiquinone biosynthesis monooxygenase COQ7",
        "protein_names_refseq": "CG14437-PA; COQ7; Coq7-PA; coenzyme Q7",
        "tax_id": 7227,
        "disease": "primary coenzyme Q10 deficiency 8 (Disease Ontology:DOID:0070245); autosomal recessive distal hereditary motor neuronopathy 9 (Disease Ontology:DOID:0081428)",
        "pathway": " (dme:Dmel_CG14437);  (R-DME-2142789)",
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        "class_list": "",
        "function": "Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner., [UniProtKB, HAMAP]",
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            {
                "id": "2.1.1.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-",
                "type": "external"
            },
            {
                "id": "2.1.1.114",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.114",
                "type": "external"
            },
            {
                "id": "2.1.1.64",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.64",
                "type": "external"
            },
            {
                "id": "1.14.15.45",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.15.45",
                "type": "external"
            },
            {
                "id": "1.14.15.46",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.15.46",
                "type": "external"
            },
            {
                "id": "4.1.1.130",
                "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.130",
                "type": "external"
            },
            {
                "id": "2.1.1.201",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.201",
                "type": "external"
            },
            {
                "id": "1.14.99.60",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.99.60",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0046872 metal ion binding;GO:0008682 3-demethoxyubiquinol 3-hydroxylase activity;GO:0160224 3-demethoxyubiquinone 3-hydroxylase (NADH) activity",
        "go_cellular_component": "GO:0031314 extrinsic component of mitochondrial inner membrane;GO:0005634 nucleus;GO:0005743 mitochondrial inner membrane;GO:0110142 ubiquinone biosynthesis complex",
        "go_biological_process": "GO:2000377 regulation of reactive oxygen species metabolic process;GO:0006744 ubiquinone biosynthetic process;GO:0008340 determination of adult lifespan",
        "synthesized_glycan_count": 0,
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                "url": "https://www.uniprot.org/uniprot/Q9W3W9",
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            }
        ],
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        "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein",
        "gene_name": "LP06294.5prime",
        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein, isoform D",
        "refseq_ac": [
            {
                "id": "NP_001284957",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284957",
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            }
        ],
        "gene_names_uniprotkb": "LP06294.5prime; BEST:LP06294; CG3168; Dmel\\CG3168; Dmel_CG3168; Slc22a18",
        "gene_names_refseq": "BEST:LP06294; CG3168; Dmel\\CG3168; LP06294.5prime; Slc22a18",
        "protein_names_uniprotkb": "Major facilitator superfamily (MFS) profile domain-containing protein",
        "protein_names_refseq": "CG3168-PD; uncharacterized protein, isoform D",
        "tax_id": 7227,
        "disease": "developmental and epileptic encephalopathy (Disease Ontology:DOID:0112202)",
        "pathway": " (dme:Dmel_CG3168)",
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        "go_molecular_function": "GO:0022857 transmembrane transporter activity",
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        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein",
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            {
                "id": "NP_572312",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572312",
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            }
        ],
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        "protein_names_refseq": "CG12219-PA; uncharacterized protein",
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        "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000976 transcription cis-regulatory region binding",
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                "id": "Q9W418_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9W418",
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        ],
        "mass": 60030.0,
        "length": 534,
        "protein_name": "Ubiquitin-5E, isoform A; Ubiquitin-5E, isoform B",
        "gene_name": "Ubi-p5E",
        "organism": "Fruit fly",
        "refseq_name": "Ubiquitin-5E, isoform B",
        "refseq_ac": [
            {
                "id": "NP_001284937",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284937",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Ubi-p5E; CG18282; CG32744; CR32744; DmUbi-p5E; DmUb; Dmel\\CG32744; Dmel_CG32744; UB; Ubiq; Ubi; Ub",
        "gene_names_refseq": "CG18282; CG32744; CR32744; DmUbi-p5E; DmUb; Dmel\\CG32744; UB; Ubi-p5E; Ubiq; Ubi; Ub",
        "protein_names_uniprotkb": "Ubiquitin-5E, isoform A; Ubiquitin-5E, isoform B",
        "protein_names_refseq": "CG32744-PB; Ubi-p5E-PB; Ubiquitin-5E, isoform B; ubiquitin",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG32744);  (R-DME-110312);  (R-DME-110314);  (R-DME-110320);  (R-DME-1169091);  (R-DME-1234176);  (R-DME-1253288);  (R-DME-1295596);  (R-DME-1358803);  (R-DME-156827);  (R-DME-174048);  (R-DME-174084);  (R-DME-174113);  (R-DME-174154);  (R-DME-174178);  (R-DME-174184);  (R-DME-179409);  (R-DME-1799339);  (R-DME-182971);  (R-DME-187577);  (R-DME-195253);  (R-DME-202424);  (R-DME-209560);  (R-DME-2122948);  (R-DME-2173788);  (R-DME-2173791);  (R-DME-2173795);  (R-DME-2173796);  (R-DME-2467813);  (R-DME-2559582);  (R-DME-2565942);  (R-DME-2871837);  (R-DME-3134975);  (R-DME-3769402);  (R-DME-382556);  (R-DME-445989);  (R-DME-450302);  (R-DME-450321);  (R-DME-450408);  (R-DME-4608870);  (R-DME-4641257);  (R-DME-4641258);  (R-DME-5205685);  (R-DME-532668);  (R-DME-5357905);  (R-DME-5358346);  (R-DME-5607761);  (R-DME-5607764);  (R-DME-5610780);  (R-DME-5610785);  (R-DME-5632684);  (R-DME-5654726);  (R-DME-5654727);  (R-DME-5654732);  (R-DME-5654733);  (R-DME-5655862);  (R-DME-5656121);  (R-DME-5656169);  (R-DME-5675221);  (R-DME-5675482);  (R-DME-5676590);  (R-DME-5689603);  (R-DME-5689877);  (R-DME-5689880);  (R-DME-5689896);  (R-DME-5689901);  (R-DME-5696394);  (R-DME-5696395);  (R-DME-5696400);  (R-DME-6781823);  (R-DME-6782135);  (R-DME-6782210);  (R-DME-6804757);  (R-DME-68867);  (R-DME-68949);  (R-DME-69017);  (R-DME-69231);  (R-DME-69601);  (R-DME-72689);  (R-DME-72706);  (R-DME-75815);  (R-DME-8849469);  (R-DME-8854050);  (R-DME-8856825);  (R-DME-8856828);  (R-DME-8863795);  (R-DME-8866427);  (R-DME-8866652);  (R-DME-8866654);  (R-DME-8939236);  (R-DME-8939902);  (R-DME-8941858);  (R-DME-8948747);  (R-DME-8948751);  (R-DME-8951664);  (R-DME-901032);  (R-DME-9010553);  (R-DME-9020702);  (R-DME-9033241);  (R-DME-912631);  (R-DME-917729);  (R-DME-917937);  (R-DME-937039);  (R-DME-937042);  (R-DME-937072);  (R-DME-9646399);  (R-DME-9648002);  (R-DME-9664873);  (R-DME-975144);  (R-DME-975163);  (R-DME-9755511);  (R-DME-975956);  (R-DME-975957);  (R-DME-9762114);  (R-DME-9770562);  (R-DME-983168);  (R-DME-9861718);  (R-DME-9929491);  (R-DME-9932298);  (R-DME-9954709);  (R-DME-9954714);  (R-DME-9954716);  (R-DME-9958825)",
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    },
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            {
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                "url": "https://www.uniprot.org/uniprot/Q9W4Y1",
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            }
        ],
        "mass": 25722.0,
        "length": 228,
        "protein_name": "aralkylamine N-acetyltransferase",
        "gene_name": "AANATL7",
        "organism": "Fruit fly",
        "refseq_name": "arylalkylamine N-acetyltransferase-like 7, isoform B",
        "refseq_ac": [
            {
                "id": "NP_001188542",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188542",
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            }
        ],
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        "protein_names_uniprotkb": "aralkylamine N-acetyltransferase; 2.3.1.87",
        "protein_names_refseq": "AANATL7-PB; CG13759-PB; arylalkylamine N-Acetyltransferase like 7; arylalkylamine N-Acetyltransferase-like 7; arylalkylamine N-acetyltransferase-like 7, isoform B",
        "tax_id": 7227,
        "disease": "",
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            {
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            },
            {
                "id": "2.3.2.-",
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            }
        ],
        "go_molecular_function": "GO:0004059 aralkylamine N-acetyltransferase activity;GO:0008080 N-acetyltransferase activity",
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    },
    {
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            {
                "id": "Q9W4Y8_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9W4Y8",
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            }
        ],
        "mass": 39241.0,
        "length": 353,
        "protein_name": "Uncharacterized protein",
        "gene_name": "EG:BACH7M4.4",
        "organism": "Fruit fly",
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            {
                "id": "NP_570003",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_570003",
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            }
        ],
        "gene_names_uniprotkb": "EG:BACH7M4.4; CG12496; Dmel\\CG12496; Dmel_CG12496",
        "gene_names_refseq": "CG12496; Dmel\\CG12496; EG:BACH7M4.4",
        "protein_names_uniprotkb": "Uncharacterized protein",
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    },
    {
        "uniprot_canonical_ac": "Q9W4Z9-1",
        "uniprot_id": [
            {
                "id": "Q9W4Z9_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9W4Z9",
                "type": "external"
            }
        ],
        "mass": 60370.0,
        "length": 535,
        "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog",
        "gene_name": "Dmel\\CG3071",
        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "NP_569993",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_569993",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Dmel\\CG3071; 3071; CG3071; Dmel_CG3071; EG:25E8.3",
        "gene_names_refseq": "3071; CG3071; Dmel\\CG3071; EG:25E8.3",
        "protein_names_uniprotkb": "U3 small nucleolar RNA-associated protein 15 homolog",
        "protein_names_refseq": "CG3071-PA; uncharacterized protein",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG3071);  (R-DME-6791226)",
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        "class_list": "",
        "function": "Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0030515 snoRNA binding",
        "go_cellular_component": "GO:0005730 nucleolus;GO:0034455 t-UTP complex",
        "go_biological_process": "GO:0006364 rRNA processing;GO:0045943 positive regulation of transcription by RNA polymerase I;GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)",
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    },
    {
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            {
                "id": "Q9W508_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9W508",
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        ],
        "mass": 57671.0,
        "length": 504,
        "protein_name": "Fatty acyl-CoA reductase",
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        "refseq_name": "fatty acyl-CoA reductase in oenocytes",
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            {
                "id": "NP_652021",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_652021",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "FarO; CG18031; Dmel\\CG18031; Dmel_CG18031; EG:103B4.2; farO",
        "gene_names_refseq": "CG18031; Dmel\\CG18031; EG:103B4.2; FarO; farO",
        "protein_names_uniprotkb": "Fatty acyl-CoA reductase; 1.2.1.84",
        "protein_names_refseq": "CG18031-PA; FarO-PA; fatty acyl-CoA reductase in oenocytes",
        "tax_id": 7227,
        "disease": "rhizomelic chondrodysplasia punctate type 4 (Disease Ontology:DOID:0081243)",
        "pathway": " (dme:Dmel_CG18031);  (R-DME-9640463)",
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        "class_list": "",
        "function": "Catalyzes the reduction of fatty acyl-CoA to fatty alcohols., [UniProtKB, UniProtKB]",
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        ],
        "go_molecular_function": "GO:0080019 alcohol-forming very long-chain fatty acyl-CoA reductase activity;GO:0102965 alcohol-forming long-chain fatty acyl-CoA reductase activity",
        "go_cellular_component": "GO:0005777 peroxisome",
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        ],
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        "length": 626,
        "protein_name": "Monocarboxylate transporter 1, isoform A; Monocarboxylate transporter 1, isoform B",
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        "refseq_name": "monocarboxylate transporter 1, isoform B",
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            {
                "id": "NP_001284810",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284810",
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        ],
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        "protein_names_refseq": "CG3456-PB; Mct1-PB; monocarboxylate transporter 1, isoform B",
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        "disease": "cataract 47 (Disease Ontology:DOID:0070353)",
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                "id": "Q9W530_DROME",
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        ],
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        "length": 205,
        "protein_name": "Uncharacterized protein",
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        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein",
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            {
                "id": "NP_569974",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_569974",
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        ],
        "gene_names_uniprotkb": "BcDNA:AT13882; CG14054; Dmel\\CG14054; Dmel_CG14054",
        "gene_names_refseq": "BcDNA:AT13882; CG14054; Dmel\\CG14054",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "CG14054-PA; uncharacterized protein",
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        "disease": "colorectal adenocarcinoma (Disease Ontology:DOID:0050861); myelodysplastic syndrome (Disease Ontology:DOID:0050908); brain glioma (Disease Ontology:DOID:0060108); colorectal carcinoma (Disease Ontology:DOID:0080199); autosomal recessive spinocerebellar ataxia 26 (Disease Ontology:DOID:0080260); prostate cancer (Disease Ontology:DOID:10283); stomach cancer (Disease Ontology:DOID:10534); hypertension (Disease Ontology:DOID:10763); urinary bladder cancer (Disease Ontology:DOID:11054); asphyxia neonatorum (Disease Ontology:DOID:11088); hepatitis A (Disease Ontology:DOID:12549); leiomyoma (Disease Ontology:DOID:127); lung cancer (Disease Ontology:DOID:1324); malignant mesothelioma (Disease Ontology:DOID:1790); pancreatic cancer (Disease Ontology:DOID:1793); impotence (Disease Ontology:DOID:1875); hepatitis B (Disease Ontology:DOID:2043); transient cerebral ischemia (Disease Ontology:DOID:224); laryngeal carcinoma (Disease Ontology:DOID:2600); transitional cell carcinoma (Disease Ontology:DOID:2671); contact dermatitis (Disease Ontology:DOID:2773); invasive ductal carcinoma (Disease Ontology:DOID:3008); glioblastoma (Disease Ontology:DOID:3068); high grade glioma (Disease Ontology:DOID:3070); gallbladder cancer (Disease Ontology:DOID:3121); coronary artery disease (Disease Ontology:DOID:3393); middle cerebral artery infarction (Disease Ontology:DOID:3525); meningioma (Disease Ontology:DOID:3565); liver cancer (Disease Ontology:DOID:3571); central nervous system cancer (Disease Ontology:DOID:3620); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); papillary thyroid carcinoma (Disease Ontology:DOID:3969); cervical cancer (Disease Ontology:DOID:4362); seminoma (Disease Ontology:DOID:4440); renal cell carcinoma (Disease Ontology:DOID:4450); esophageal cancer (Disease Ontology:DOID:5041); liver cirrhosis (Disease Ontology:DOID:5082); stomach carcinoma (Disease Ontology:DOID:5517); gastric cardia carcinoma (Disease Ontology:DOID:6270); gastric cardia adenocarcinoma (Disease Ontology:DOID:6271); hepatocellular carcinoma (Disease Ontology:DOID:684); chronic myeloid leukemia (Disease Ontology:DOID:8552); in situ carcinoma (Disease Ontology:DOID:8719); diabetic retinopathy (Disease Ontology:DOID:8947); colorectal cancer (Disease Ontology:DOID:9256); nasopharynx carcinoma (Disease Ontology:DOID:9261); type 2 diabetes mellitus (Disease Ontology:DOID:9352); oral mucosa leukoplakia (Disease Ontology:DOID:9655); senile cataract (Disease Ontology:DOID:9669); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)",
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        "disease": "alcohol dependence (Disease Ontology:DOID:0050741); stroke (Disease Ontology:DOID:0051061); Hirschsprung's disease (Disease Ontology:DOID:10487); stomach cancer (Disease Ontology:DOID:10534); Alzheimer's disease (Disease Ontology:DOID:10652); Huntington's disease (Disease Ontology:DOID:12858); Parkinson's disease (Disease Ontology:DOID:14330); epilepsy (Disease Ontology:DOID:1826); cannabis dependence (Disease Ontology:DOID:1849); multiple sclerosis (Disease Ontology:DOID:2377); gastrointestinal system cancer (Disease Ontology:DOID:3119); liver cancer (Disease Ontology:DOID:3571); myasthenia gravis (Disease Ontology:DOID:437); hepatocellular carcinoma (Disease Ontology:DOID:684); subacute delirium (Disease Ontology:DOID:8645); colorectal cancer (Disease Ontology:DOID:9256); bacterial meningitis (Disease Ontology:DOID:9470); type 1 diabetes mellitus (Disease Ontology:DOID:9744); drug dependence (Disease Ontology:DOID:9974); heroin dependence (Disease Ontology:DOID:9976)",
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        "disease": "attention deficit hyperactivity disorder (Disease Ontology:DOID:1094)",
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        "go_biological_process": "GO:0036258 multivesicular body assembly;GO:0097352 autophagosome maturation;GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0016322 neuron remodeling;GO:0051301 cell division",
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