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        ],
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                "id": "3.6.1.15",
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                "id": "3.6.1.-",
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            },
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                "id": "5.6.1.7",
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            },
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                "id": "3.1.4.-",
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                "id": "3.4.21.53",
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            }
        ],
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    },
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            }
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            {
                "id": "XP_024854561",
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                "id": "2.7.11.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-",
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            },
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                "id": "2.7.11.4",
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            },
            {
                "id": "2.7.2.3",
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            },
            {
                "id": "2.7.11.10",
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            }
        ],
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        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005944 phosphatidylinositol 3-kinase complex, class IB;GO:0005943 phosphatidylinositol 3-kinase complex, class IA",
        "go_biological_process": "GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process;GO:0016477 cell migration;GO:0040012 regulation of locomotion;GO:0048015 phosphatidylinositol-mediated signaling;GO:0043491 phosphatidylinositol 3-kinase/protein kinase B signal transduction",
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    },
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        ],
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            {
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    },
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        ],
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            {
                "id": "XP_003585731",
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            }
        ],
        "gene_names_uniprotkb": "MECOM",
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        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0045892 negative regulation of DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription;GO:0032259 methylation",
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    },
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            {
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        ],
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        "protein_name": "Peptidoglycan recognition protein 1",
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            {
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        ],
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        "function": "Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Also binds to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0032991 protein-containing complex",
        "go_biological_process": "GO:0045087 innate immune response;GO:0009253 peptidoglycan catabolic process;GO:0042742 defense response to bacterium;GO:0031640 killing of cells of another organism;GO:0050832 defense response to fungus",
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    },
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        ],
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        "protein_name": "Regulating synaptic membrane exocytosis 3",
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        "refseq_name": "regulating synaptic membrane exocytosis protein 3",
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            {
                "id": "NP_001192796",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192796",
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            }
        ],
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        "gene_names_refseq": "RIMS3",
        "protein_names_uniprotkb": "Regulating synaptic membrane exocytosis 3",
        "protein_names_refseq": "regulating synaptic membrane exocytosis protein 3",
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        "go_molecular_function": "GO:0031267 small GTPase binding",
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            }
        ],
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        "protein_name": "Brother of CDO",
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        "organism": "Bovine",
        "refseq_name": "brother of CDO isoform X1",
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            {
                "id": "XP_015326555",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015326555",
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        ],
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        "protein_names_refseq": "brother of CDO isoform X1",
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        "pathway": " (bta:512018);  (R-BTA-525793);  (R-BTA-5635838)",
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        "function": "Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells., [UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:0030424 axon",
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            {
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        ],
        "mass": 51118.0,
        "length": 463,
        "protein_name": "Mitochondrial elongation factor 1",
        "gene_name": "MIEF1",
        "organism": "Bovine",
        "refseq_name": "mitochondrial dynamics protein MIEF1",
        "refseq_ac": [
            {
                "id": "NP_001193055",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193055",
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            }
        ],
        "gene_names_uniprotkb": "MIEF1",
        "gene_names_refseq": "MIEF1; SMCR7L",
        "protein_names_uniprotkb": "Mitochondrial elongation factor 1; Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like",
        "protein_names_refseq": "Smith-Magenis syndrome chromosome region, candidate 7-like; mitochondrial dynamics protein MIEF1",
        "tax_id": 9913,
        "disease": "",
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        "function": "Mitochondrial outer membrane protein which regulates mitochondrial fission/fusion dynamics. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. Inhibits DNM1L GTPase activity in the absence of bound ADP. Requires ADP to stimulate DNM1L GTPase activity and the assembly of DNM1L into long, oligomeric tubules with a spiral pattern, as opposed to the ring-like DNM1L oligomers observed in the absence of bound ADP. Does not require ADP for its function in recruiting DNM1L., [UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0042802 identical protein binding;GO:0043531 ADP binding;GO:0019003 GDP binding",
        "go_cellular_component": "GO:0005741 mitochondrial outer membrane",
        "go_biological_process": "GO:0010636 positive regulation of mitochondrial fusion;GO:0090314 positive regulation of protein targeting to membrane;GO:0000266 mitochondrial fission;GO:0090141 positive regulation of mitochondrial fission;GO:0007005 mitochondrion organization",
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    },
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        ],
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        "protein_name": "Olfactory receptor",
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        ],
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        "missing_score": 10000,
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        "go_cellular_component": "",
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    },
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        ],
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        "protein_name": "Cytochrome c oxidase subunit 7B, mitochondrial",
        "gene_name": "",
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        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Cytochrome c oxidase subunit 7B, mitochondrial; Cytochrome c oxidase polypeptide VIIb",
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        "ec_number_list": [],
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        "go_cellular_component": "GO:0005743 mitochondrial inner membrane",
        "go_biological_process": "GO:0006123 mitochondrial electron transport, cytochrome c to oxygen",
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        "hit_score": 0.1,
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    },
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        ],
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        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Uncharacterized protein",
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    {
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            {
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            }
        ],
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        "length": 455,
        "protein_name": "Acylglycerol transacylase",
        "gene_name": "PNPLA3",
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        "ec_number_list": [
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                "id": "3.1.1.32",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32",
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            },
            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3",
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            {
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            },
            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5",
                "type": "external"
            },
            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.23",
                "type": "external"
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            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.79",
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            {
                "id": "2.3.1.51",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51",
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            },
            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.26",
                "type": "external"
            },
            {
                "id": "2.3.1.23",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.23",
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            },
            {
                "id": "2.3.1.67",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.67",
                "type": "external"
            },
            {
                "id": "2.3.1.25",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.25",
                "type": "external"
            },
            {
                "id": "3.1.1.116",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.116",
                "type": "external"
            },
            {
                "id": "3.1.1.34",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.34",
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            },
            {
                "id": "3.1.1.13",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.13",
                "type": "external"
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            {
                "id": "3.1.1.6",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.6",
                "type": "external"
            }
        ],
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        "go_cellular_component": "",
        "go_biological_process": "GO:0019433 triglyceride catabolic process",
        "synthesized_glycan_count": 0,
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    },
    {
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            {
                "id": "A0ABI0NMZ8_BOVIN",
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                "type": "external"
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        ],
        "mass": 61048.0,
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        "protein_name": "C2H2-type domain-containing protein",
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        "protein_names_uniprotkb": "C2H2-type domain-containing protein",
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        "function": "May function as a transcription factor., [UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006351 DNA-templated transcription",
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    {
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        ],
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        "protein_name": "40S ribosomal protein S24",
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        "gene_names_refseq": "",
        "protein_names_uniprotkb": "40S ribosomal protein S24",
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                "id": "1.2.1.28",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.28",
                "type": "external"
            },
            {
                "id": "1.2.1.7",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.7",
                "type": "external"
            },
            {
                "id": "1.2.1.48",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.48",
                "type": "external"
            },
            {
                "id": "1.1.1.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.-",
                "type": "external"
            },
            {
                "id": "1.14.19.17",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.19.17",
                "type": "external"
            },
            {
                "id": "5.2.1.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.-",
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            },
            {
                "id": "3.6.4.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0004392 heme oxygenase (decyclizing) activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
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        "synthesized_glycan_count": 0,
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    },
    {
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            {
                "id": "A0ABI0NZQ6_BOVIN",
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            }
        ],
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        "protein_name": "Sodium channel epithelial 1 subunit delta",
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        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Sodium channel epithelial 1 subunit delta",
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        "tax_id": 9913,
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        "pathway": " (bta:528813);  (R-BTA-2672351);  (R-BTA-9730628)",
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            {
                "id": "1.8.-.-",
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            }
        ],
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    },
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            {
                "id": "A0ABI0NWE4_BOVIN",
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        ],
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            {
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        ],
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        "go_cellular_component": "GO:0000139 Golgi membrane",
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            }
        ],
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        "function": "As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator plays a dual role for the small GTPases Rag (RagA/RRAGA, RagB/RRAGB, RagC/RRAGC and/or RagD/RRAGD): it (1) acts as a guanine nucleotide exchange factor (GEF), activating the small GTPases Rag and (2) mediates recruitment of Rag GTPases to the lysosome membrane. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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            }
        ],
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        "protein_name": "Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1",
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        "gene_names_uniprotkb": "GBF1",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1",
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        "tax_id": 9913,
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        "pathway": " (R-BTA-199992);  (R-BTA-5620916);  (R-BTA-6807878);  (R-BTA-6811434)",
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        "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity",
        "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005811 lipid droplet;GO:0016020 membrane;GO:0005793 endoplasmic reticulum-Golgi intermediate compartment;GO:0000137 Golgi cis cisterna",
        "go_biological_process": "GO:0016192 vesicle-mediated transport;GO:0032012 regulation of ARF protein signal transduction;GO:0015031 protein transport;GO:0016197 endosomal transport;GO:0010256 endomembrane system organization",
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    {
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            {
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            }
        ],
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        "protein_name": "GDNF-inducible zinc finger protein 1",
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        "gene_names_uniprotkb": "GZF1",
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        "protein_names_uniprotkb": "GDNF-inducible zinc finger protein 1; Zinc finger protein 336",
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        "pathway": " (bta:525199)",
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        "function": "Transcriptional repressor that binds the GZF1 responsive element (GRE) (consensus: 5'-TGCGCN[TG][CA]TATA-3'). May be regulating VSX2/HOX10 expression., [UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II",
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    },
    {
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        ],
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        "protein_name": "E2 ubiquitin-conjugating enzyme",
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        "protein_names_uniprotkb": "E2 ubiquitin-conjugating enzyme; 2.3.2.23",
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        "ec_number_list": [
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            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23",
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        ],
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            {
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        "function": "Helicase component of the SKI complex, a multiprotein complex that assists the RNA-degrading exosome during the mRNA decay and quality-control pathways. The SKI complex catalyzes mRNA extraction from 80S ribosomal complexes in the 3'-5' direction and channels mRNA to the cytosolic exosome for degradation. SKI-mediated extraction of mRNA from stalled ribosomes allow binding of the Pelota-HBS1L complex and subsequent ribosome disassembly by ABCE1 for ribosome recycling. In the nucleus, the SKI complex associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C). May play a role in the non-stop mRNA decay pathway (NSD), which specifically targets and degrades mRNAs that lack a proper stop codon., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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            {
                "id": "5.6.2.3",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3",
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            },
            {
                "id": "3.6.5.-",
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            },
            {
                "id": "5.6.2.-",
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            {
                "id": "2.7.4.3",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3",
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            },
            {
                "id": "3.6.4.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-",
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            },
            {
                "id": "2.7.11.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1",
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            },
            {
                "id": "3.1.-.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-",
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            },
            {
                "id": "4.2.99.18",
                "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18",
                "type": "external"
            },
            {
                "id": "5.6.1.6",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6",
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            },
            {
                "id": "3.6.1.15",
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            {
                "id": "7.6.2.1",
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            },
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            },
            {
                "id": "3.4.24.-",
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            },
            {
                "id": "3.6.-.-",
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            },
            {
                "id": "3.6.1.-",
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            {
                "id": "3.1.4.-",
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            },
            {
                "id": "3.4.21.53",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003724 RNA helicase activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0055087 Ski complex",
        "go_biological_process": "GO:0006402 mRNA catabolic process;GO:0006401 RNA catabolic process;GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay",
        "synthesized_glycan_count": 0,
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    },
    {
        "uniprot_canonical_ac": "A0ABI0P2G7-1",
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            {
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            }
        ],
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        "protein_name": "Actin-associated protein FAM107A",
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    {
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        ],
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        ],
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        "protein_name": "Pyroglutamyl-peptidase I",
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            {
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        "function": "Removes 5-oxoproline from various penultimate amino acid residues except L-proline., [UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0008234 cysteine-type peptidase activity;GO:0016920 pyroglutamyl-peptidase activity",
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        "record_id": "A0ABI0P0F9-1",
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        ],
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        "length": 903,
        "protein_name": "ZZ-type zinc finger-containing protein 3",
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            {
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        ],
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        "gene_names_refseq": "ZZZ3",
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        "protein_names_refseq": "ZZ-type zinc finger-containing protein 3 isoform X1",
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        "function": "Histone H3 reader that is required for the ATAC complex-mediated maintenance of histone acetylation and gene activation. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4., [UniProtKB, UniProtKB, UniProtKB]",
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        ],
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            {
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        "pathway": " (R-BTA-1227986);  (R-BTA-1236394);  (R-BTA-1250196);  (R-BTA-1250342);  (R-BTA-1250347);  (R-BTA-1257604);  (R-BTA-1306955);  (R-BTA-1358803);  (R-BTA-1963640);  (R-BTA-1963642);  (R-BTA-5673001);  (R-BTA-6785631);  (R-BTA-6811558);  (R-BTA-8847993);  (R-BTA-8863795)",
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        ],
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        "protein_names_uniprotkb": "Small nuclear ribonucleoprotein Sm D3; Sm-D3; snRNP core protein D3",
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        "pathway": " (R-BTA-111367);  (R-BTA-191859);  (R-BTA-72163);  (R-BTA-72165);  (R-BTA-73856);  (R-BTA-77588);  (R-BTA-9770562);  (R-BTA-9943411)",
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        "function": "Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "function": "Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Catalyzes the first irreversible step in ketogenesis, condensing acetyl-CoA to acetoacetyl-CoA to form HMG-CoA, which is converted by HMG-CoA reductase (HMGCR) into mevalonate., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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            }
        ],
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        "protein_name": "Nuclear mitotic apparatus protein 1",
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        ],
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        "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]; Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]",
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        "function": "ATP-dependent RNA helicase that plays a role in the regulation of R-loop homeostasis in both endogenous R-loop-prone regions and at sites of DNA damage. At endogenous loci such as actively transcribed genes, may act as a helicase to resolve the formation of R-loop during transcription and prevent the interference of R-loop with DNA-replication machinery. Also participates in the removal of DNA-lesion-associated R-loop. Plays an essential role for establishing pluripotency during embryogenesis and for pluripotency maintenance in embryonic stem cells. Mechanistically, prevents the polycomb repressive complex 2 (PRC2) from accessing rDNA loci and protects the active chromatin status in nucleolus., [UniProtKB, UniProtKB]; RNA helicase., [UniProtKB, UniProtKB]",
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