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        "protein_name": "Eyes absent homolog",
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            {
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            }
        ],
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        "protein_names_refseq": "eyes absent homolog 4 isoform X1",
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            {
                "id": "3.1.3.16",
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            {
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            },
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            },
            {
                "id": "3.1.3.67",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67",
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            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.5",
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                "id": "2.7.11.1",
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            {
                "id": "3.1.3.18",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.18",
                "type": "external"
            }
        ],
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    {
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        "refseq_name": "zinc finger MYND domain-containing protein 10",
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            {
                "id": "NP_001421897",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421897",
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            }
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        "go_cellular_component": "GO:0005737 cytoplasm;GO:0016324 apical plasma membrane;GO:0034451 centriolar satellite;GO:0120293 dynein axonemal particle",
        "go_biological_process": "GO:0044458 motile cilium assembly;GO:0036158 outer dynein arm assembly;GO:1905505 positive regulation of motile cilium assembly;GO:0036159 inner dynein arm assembly",
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            {
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        "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific",
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        "record_type": "protein",
        "filter_code": "0000000.0000000.010000.010000000000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E1BDK6-1",
        "uniprot_id": [
            {
                "id": "E1BDK6_BOVIN",
                "url": "https://www.uniprot.org/uniprot/E1BDK6",
                "type": "external"
            }
        ],
        "mass": 196009.0,
        "length": 1802,
        "protein_name": "Laminin subunit beta-2",
        "gene_name": "LAMB2",
        "organism": "Bovine",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "LAMB2",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Laminin subunit beta-2; Laminin-11 subunit beta; Laminin-14 subunit beta; Laminin-15 subunit beta; Laminin-3 subunit beta; Laminin-4 subunit beta; Laminin-7 subunit beta; Laminin-9 subunit beta; S-laminin subunit beta",
        "protein_names_refseq": "",
        "tax_id": 9913,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
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        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005178 integrin binding;GO:0150043 structural constituent of synapse-associated extracellular matrix",
        "go_cellular_component": "GO:0031594 neuromuscular junction;GO:0043083 synaptic cleft;GO:0043256 laminin complex;GO:0005608 laminin-3 complex",
        "go_biological_process": "GO:0016477 cell migration;GO:0009887 animal organ morphogenesis;GO:0034446 substrate adhesion-dependent cell spreading;GO:0007411 axon guidance;GO:0009888 tissue development",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "E1BDK6-1",
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        "filter_code": "0000000.0000000.010000.010000000000000000.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E1BDU0-1",
        "uniprot_id": [
            {
                "id": "E1BDU0_BOVIN",
                "url": "https://www.uniprot.org/uniprot/E1BDU0",
                "type": "external"
            }
        ],
        "mass": 106551.0,
        "length": 925,
        "protein_name": "Nuclear pore complex protein",
        "gene_name": "NUP107",
        "organism": "Bovine",
        "refseq_name": "nuclear pore complex protein Nup107 isoform X2",
        "refseq_ac": [
            {
                "id": "XP_002687439",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002687439",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "NUP107",
        "gene_names_refseq": "NUP107",
        "protein_names_uniprotkb": "Nuclear pore complex protein",
        "protein_names_refseq": "nuclear pore complex protein Nup107 isoform X2",
        "tax_id": 9913,
        "disease": "",
        "pathway": " (bta:504823);  (R-BTA-141430);  (R-BTA-141444);  (R-BTA-159227);  (R-BTA-159230);  (R-BTA-159231);  (R-BTA-159236);  (R-BTA-1855170);  (R-BTA-1855196);  (R-BTA-1855229);  (R-BTA-191859);  (R-BTA-2467813);  (R-BTA-2500257);  (R-BTA-3108214);  (R-BTA-3232142);  (R-BTA-3301854);  (R-BTA-3371453);  (R-BTA-4085377);  (R-BTA-4551638);  (R-BTA-4570464);  (R-BTA-4615885);  (R-BTA-5663220);  (R-BTA-9615933);  (R-BTA-9648025)",
        "pathway_count": 24,
        "publication_count": 0,
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        "class_list": "",
        "function": "Functions as a component of the nuclear pore complex (NPC)., [UniProtKB, UniProtKB]; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC. Involved in nephrogenesis., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0017056 structural constituent of nuclear pore",
        "go_cellular_component": "GO:0031080 nuclear pore outer ring;GO:0031965 nuclear membrane;GO:0000776 kinetochore;GO:0034399 nuclear periphery",
        "go_biological_process": "GO:0072006 nephron development;GO:0006406 mRNA export from nucleus;GO:0008585 female gonad development;GO:0051292 nuclear pore complex assembly;GO:0000973 post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery",
        "synthesized_glycan_count": 0,
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        "kg_view_protein": true
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    {
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            {
                "id": "E1BDU6_BOVIN",
                "url": "https://www.uniprot.org/uniprot/E1BDU6",
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            }
        ],
        "mass": 75725.0,
        "length": 677,
        "protein_name": "ATP binding cassette subfamily G member 1",
        "gene_name": "ABCG1",
        "organism": "Bovine",
        "refseq_name": "ATP-binding cassette sub-family G member 1",
        "refseq_ac": [
            {
                "id": "NP_001192457",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192457",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ABCG1",
        "gene_names_refseq": "ABCG1",
        "protein_names_uniprotkb": "ATP binding cassette subfamily G member 1",
        "protein_names_refseq": "ATP-binding cassette sub-family G member 1; ATP-binding cassette, sub-family G (WHITE), member 1",
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        "disease": "",
        "pathway": " (bta:510745)",
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        "publication_id_list": "19372466",
        "class_list": "",
        "function": "Aortic endothelial cells transcytose high-density lipoproteins by mechanisms that involve either SR-BI or ABCG1 but not ABCA1., [RefSeq, PubMed]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0005524 ATP binding;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0016887 ATP hydrolysis activity;GO:0043531 ADP binding",
        "go_cellular_component": "GO:0005739 mitochondrion;GO:0005794 Golgi apparatus;GO:0009897 external side of plasma membrane",
        "go_biological_process": "GO:0008203 cholesterol metabolic process;GO:0033700 phospholipid efflux;GO:1902004 positive regulation of amyloid-beta formation;GO:0050714 positive regulation of protein secretion;GO:0032367 intracellular cholesterol transport",
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    {
        "uniprot_canonical_ac": "E1BDW8-1",
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            {
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                "url": "https://www.uniprot.org/uniprot/E1BDW8",
                "type": "external"
            }
        ],
        "mass": 68907.0,
        "length": 606,
        "protein_name": "Polypeptide N-acetylgalactosaminyltransferase",
        "gene_name": "GALNT11",
        "organism": "Bovine",
        "refseq_name": "polypeptide N-acetylgalactosaminyltransferase 11 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_002687097",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002687097",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "GALNT11",
        "gene_names_refseq": "GALNT11",
        "protein_names_uniprotkb": "Polypeptide N-acetylgalactosaminyltransferase; 2.4.1.-; Protein-UDP acetylgalactosaminyltransferase",
        "protein_names_refseq": "polypeptide N-acetylgalactosaminyltransferase 11 isoform X1",
        "tax_id": 9913,
        "disease": "",
        "pathway": " (bta:534904);  (R-BTA-913709)",
        "pathway_count": 2,
        "publication_count": 0,
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        "class_list": "",
        "function": "Polypeptide N-acetylgalactosaminyltransferase that catalyzes the initiation of protein O-linked glycosylation and is involved in left/right asymmetry by mediating O-glycosylation of NOTCH1. O-glycosylation of NOTCH1 promotes activation of NOTCH1, modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO). Polypeptide N-acetylgalactosaminyltransferases catalyze the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays the same enzyme activity toward MUC1, MUC4, and EA2 than GALNT1. Not involved in glycosylation of erythropoietin (EPO)., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "secondary_ac_list": "",
        "ec_number_list": [
            {
                "id": "2.4.1.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.-",
                "type": "external"
            },
            {
                "id": "2.4.1.41",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.41",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0005112 Notch binding;GO:0030246 carbohydrate binding;GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity",
        "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus",
        "go_biological_process": "GO:0007219 Notch signaling pathway;GO:0006493 protein O-linked glycosylation;GO:0008593 regulation of Notch signaling pathway",
        "synthesized_glycan_count": 7434,
        "hit_score": 0.1,
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        "kg_view_protein": true
    },
    {
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            {
                "id": "E1BDZ1_BOVIN",
                "url": "https://www.uniprot.org/uniprot/E1BDZ1",
                "type": "external"
            }
        ],
        "mass": 21459.0,
        "length": 189,
        "protein_name": "Uncharacterized protein",
        "gene_name": "LOC523244",
        "organism": "Bovine",
        "refseq_name": "interferon alpha-B-like",
        "refseq_ac": [
            {
                "id": "XP_010806062",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010806062",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC523244",
        "gene_names_refseq": "LOC523244",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "interferon alpha-B-like",
        "tax_id": 9913,
        "disease": "",
        "pathway": " (bta:523244);  (R-BTA-909733);  (R-BTA-912694)",
        "pathway_count": 3,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0005125 cytokine activity;GO:0005132 type I interferon receptor binding",
        "go_cellular_component": "GO:0005615 extracellular space",
        "go_biological_process": "GO:0002312 B cell activation involved in immune response;GO:0051607 defense response to virus;GO:0060337 type I interferon-mediated signaling pathway;GO:0002250 adaptive immune response;GO:0043330 response to exogenous dsRNA",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
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        "kg_view_protein": true
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    {
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            {
                "id": "E1BE31_BOVIN",
                "url": "https://www.uniprot.org/uniprot/E1BE31",
                "type": "external"
            }
        ],
        "mass": 110565.0,
        "length": 987,
        "protein_name": "Junction mediating and regulatory protein, p53 cofactor",
        "gene_name": "JMY",
        "organism": "Bovine",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "JMY",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Junction mediating and regulatory protein, p53 cofactor",
        "protein_names_refseq": "",
        "tax_id": 9913,
        "disease": "",
        "pathway": " (R-BTA-6804760)",
        "pathway_count": 1,
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        "predicted_glycosites": 1,
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0003779 actin binding;GO:0008017 microtubule binding;GO:0071933 Arp2/3 complex binding",
        "go_cellular_component": "GO:0000421 autophagosome membrane;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0031252 cell leading edge;GO:0030659 cytoplasmic vesicle membrane",
        "go_biological_process": "GO:0070060 'de novo' actin filament nucleation;GO:0043065 positive regulation of apoptotic process;GO:0034314 Arp2/3 complex-mediated actin nucleation;GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator;GO:0009267 cellular response to starvation",
        "synthesized_glycan_count": 0,
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        "filter_code": "0000000.0000001.010000.010000000000000000.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
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                "url": "https://www.uniprot.org/uniprot/E1BE68",
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            {
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            {
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            },
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                "id": "3.6.5.2",
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        ],
        "go_molecular_function": "GO:0005524 ATP binding;GO:0030276 clathrin binding;GO:0035091 phosphatidylinositol binding;GO:0016303 1-phosphatidylinositol-3-kinase activity;GO:0046934 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity",
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        ],
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        "refseq_name": "tripartite motif-containing protein 72",
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            {
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        "function": "Muscle-specific E3 ubiquitin-protein ligase that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Its ubiquitination activity is mediated by E2 ubiquitin-conjugating enzymes UBE2D1, UBE2D2 and UBE2D3. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca(2+)-dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles., [UniProtKB, UniProtKB]",
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        "function": "Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code., [UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003714 transcription corepressor activity;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding;GO:0003700 DNA-binding transcription factor activity",
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        "protein_names_uniprotkb": "Glutathione S-transferase omega; 1.20.4.2; 1.8.5.1; 2.5.1.18; GSTO; Glutathione-dependent dehydroascorbate reductase; Monomethylarsonic acid reductase",
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        "function": "Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; GSTO2 is transported and deposited in the postacrosomal sheath (PAS) region by the manchette, and that the late assembly of GSTO2 and its localization in the PAS suggests a role in regulating the oxidative and reductive state of covalently linked spermatid/sperm proteins, especially during the disassembly of the sperm accessory structures after fertilization, [RefSeq, PubMed]",
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        "function": "Dephosphorylates and concomitantly deactivates CaM-kinase II activated upon autophosphorylation, and CaM-kinases IV and I activated upon phosphorylation by CaM-kinase kinase. Promotes apoptosis., [UniProtKB, UniProtKB]",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.-.-.-",
                "type": "external"
            },
            {
                "id": "3.1.1.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.-",
                "type": "external"
            },
            {
                "id": "3.1.1.32",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32",
                "type": "external"
            },
            {
                "id": "2.3.1.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0005543 phospholipid binding;GO:0005198 structural molecule activity;GO:0005509 calcium ion binding;GO:0004623 phospholipase A2 activity",
        "go_cellular_component": "GO:0005576 extracellular region;GO:0031012 extracellular matrix",
        "go_biological_process": "GO:0016042 lipid catabolic process;GO:0050482 arachidonate secretion;GO:0046470 phosphatidylcholine metabolic process;GO:0046471 phosphatidylglycerol metabolic process;GO:0045299 otolith mineralization",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "E1BG04-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.010000000000000000.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E1BG49-1",
        "uniprot_id": [
            {
                "id": "E1BG49_BOVIN",
                "url": "https://www.uniprot.org/uniprot/E1BG49",
                "type": "external"
            }
        ],
        "mass": 309255.0,
        "length": 2640,
        "protein_name": "Centromere-associated protein E",
        "gene_name": "CENPE",
        "organism": "Bovine",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "CENPE",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Centromere-associated protein E; Centromere protein E",
        "protein_names_refseq": "",
        "tax_id": 9913,
        "disease": "",
        "pathway": " (R-BTA-141430);  (R-BTA-141444);  (R-BTA-2132295);  (R-BTA-2467813);  (R-BTA-2500257);  (R-BTA-5663220);  (R-BTA-9648025);  (R-BTA-983189)",
        "pathway_count": 8,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
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        "reported_glycation": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0003777 microtubule motor activity;GO:0043515 kinetochore binding",
        "go_cellular_component": "GO:0005828 kinetochore microtubule;GO:0005634 nucleus;GO:0005874 microtubule;GO:0000776 kinetochore;GO:0030496 midbody",
        "go_biological_process": "GO:0051382 kinetochore assembly;GO:0007079 mitotic chromosome movement towards spindle pole;GO:0099606 microtubule plus-end directed mitotic chromosome migration;GO:0099607 lateral attachment of mitotic spindle microtubules to kinetochore;GO:0000278 mitotic cell cycle",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "E1BG49-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.001000.010000000000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E1BG51-1",
        "uniprot_id": [
            {
                "id": "E1BG51_BOVIN",
                "url": "https://www.uniprot.org/uniprot/E1BG51",
                "type": "external"
            }
        ],
        "mass": 62265.0,
        "length": 573,
        "protein_name": "Solute carrier family 41 member",
        "gene_name": "SLC41A2",
        "organism": "Bovine",
        "refseq_name": "solute carrier family 41 member 2",
        "refseq_ac": [
            {
                "id": "NP_001192839",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192839",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "SLC41A2",
        "gene_names_refseq": "SLC41A2",
        "protein_names_uniprotkb": "Solute carrier family 41 member",
        "protein_names_refseq": "solute carrier family 41 member 2",
        "tax_id": 9913,
        "disease": "",
        "pathway": " (bta:524417);  (R-BTA-425410)",
        "pathway_count": 2,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "Acts as a magnesium transporter., [UniProtKB, UniProtKB]; Acts as a plasma-membrane magnesium transporter. Can also mediate the transport of other divalent metal cations in an order of Ba(2+) > Ni(2+) > Co(2+) > Fe(2+) > Mn(2+)., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_c_glycosites": 0,
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        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
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        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
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        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [
            {
                "id": "2.7.11.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0008324 monoatomic cation transmembrane transporter activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0015693 magnesium ion transport;GO:0006826 iron ion transport;GO:0006828 manganese ion transport;GO:0015675 nickel cation transport;GO:0006824 cobalt ion transport",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "E1BG51-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.010000000000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E1BG63-1",
        "uniprot_id": [
            {
                "id": "E1BG63_BOVIN",
                "url": "https://www.uniprot.org/uniprot/E1BG63",
                "type": "external"
            }
        ],
        "mass": 104247.0,
        "length": 918,
        "protein_name": "Protein O-mannosyl-transferase TMTC3",
        "gene_name": "TMTC3",
        "organism": "Bovine",
        "refseq_name": "protein O-mannosyl-transferase TMTC3",
        "refseq_ac": [
            {
                "id": "XP_002687234",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002687234",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "TMTC3",
        "gene_names_refseq": "TMTC3",
        "protein_names_uniprotkb": "Protein O-mannosyl-transferase TMTC3; 2.4.1.109; Transmembrane O-mannosyltransferase targeting cadherins 3; Transmembrane and tetratricopeptide repeat-containing 3",
        "protein_names_refseq": "protein O-mannosyl-transferase TMTC3",
        "tax_id": 9913,
        "disease": "",
        "pathway": " (bta:522132)",
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        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O-mannosyl-transferase on other proteins such as PDIA3. Involved in the positive regulation of proteasomal protein degradation in the endoplasmic reticulum (ER), and the control of ER stress response., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity;GO:0000030 mannosyltransferase activity",
        "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane",
        "go_biological_process": "GO:0034976 response to endoplasmic reticulum stress;GO:0035269 protein O-linked glycosylation via mannose;GO:1901800 positive regulation of proteasomal protein catabolic process",
        "synthesized_glycan_count": 0,
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        "record_id": "E1BG63-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.010000.010000000000000000.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E1BGA4-1",
        "uniprot_id": [
            {
                "id": "E1BGA4_BOVIN",
                "url": "https://www.uniprot.org/uniprot/E1BGA4",
                "type": "external"
            }
        ],
        "mass": 325912.0,
        "length": 2905,
        "protein_name": "Histone-lysine N-methyltransferase ASH1L",
        "gene_name": "ASH1L",
        "organism": "Bovine",
        "refseq_name": "histone-lysine N-methyltransferase ASH1L isoform X2",
        "refseq_ac": [
            {
                "id": "XP_010801226",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010801226",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ASH1L",
        "gene_names_refseq": "ASH1L",
        "protein_names_uniprotkb": "Histone-lysine N-methyltransferase ASH1L; 2.1.1.359; 2.1.1.367; ASH1-like protein; Absent small and homeotic disks protein 1 homolog",
        "protein_names_refseq": "histone-lysine N-methyltransferase ASH1L isoform X2",
        "tax_id": 9913,
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        "pathway": " (R-BTA-3214841)",
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        "function": "Histone methyltransferase specifically trimethylating 'Lys-36' of histone H3 forming H3K36me3. Also monomethylates 'Lys-9' of histone H3 (H3K9me1) in vitro. The physiological significance of the H3K9me1 activity is unclear., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
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        "reported_c_glycosites_with_glycan": 0,
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        "total_reported_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": [
            {
                "id": "2.1.1.359",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.359",
                "type": "external"
            },
            {
                "id": "2.1.1.355",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.355",
                "type": "external"
            },
            {
                "id": "2.1.1.354",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.354",
                "type": "external"
            },
            {
                "id": "2.1.1.362",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.362",
                "type": "external"
            },
            {
                "id": "2.1.1.361",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.361",
                "type": "external"
            },
            {
                "id": "2.1.1.372",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.372",
                "type": "external"
            },
            {
                "id": "2.1.1.367",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.367",
                "type": "external"
            },
            {
                "id": "2.1.1.366",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.366",
                "type": "external"
            },
            {
                "id": "2.1.1.357",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.357",
                "type": "external"
            },
            {
                "id": "2.1.1.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0042800 histone H3K4 methyltransferase activity;GO:0140948 histone H3K9 monomethyltransferase activity",
        "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005923 bicellular tight junction;GO:0016604 nuclear body;GO:0005694 chromosome",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0032259 methylation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "E1BGA4-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.001000.010000000000000000.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E1BGC2-1",
        "uniprot_id": [
            {
                "id": "E1BGC2_BOVIN",
                "url": "https://www.uniprot.org/uniprot/E1BGC2",
                "type": "external"
            }
        ],
        "mass": 45398.0,
        "length": 405,
        "protein_name": "Fatty acid 2-hydroxylase",
        "gene_name": "FA2H",
        "organism": "Bovine",
        "refseq_name": "fatty acid 2-hydroxylase isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005218405",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218405",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "FA2H",
        "gene_names_refseq": "FA2H",
        "protein_names_uniprotkb": "Fatty acid 2-hydroxylase; Fatty acid alpha-hydroxylase",
        "protein_names_refseq": "fatty acid 2-hydroxylase isoform X1",
        "tax_id": 9913,
        "disease": "",
        "pathway": " (R-BTA-1660661)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "Catalyzes the hydroxylation of free fatty acids at the C-2 position to produce 2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. FA2H is stereospecific for the production of (R)-2-hydroxy fatty acids. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters in sebaceous gland, specifically regulating hair follicle homeostasis. Involved in the synthesis of sphingolipids of plasma membrane rafts, controlling lipid raft mobility and trafficking of raft-associated proteins., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
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        "reported_c_glycosites_with_glycan": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005506 iron ion binding;GO:0080132 fatty acid 2-hydroxylase activity;GO:0120520 free fatty acid 2-hydroxylase activity;GO:0120521 4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase activity",
        "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane",
        "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0061436 establishment of skin barrier;GO:0006633 fatty acid biosynthetic process;GO:0006682 galactosylceramide biosynthetic process;GO:0006679 glucosylceramide biosynthetic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "E1BGC2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.010000000000000000.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E1BGG5-1",
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            {
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                "url": "https://www.uniprot.org/uniprot/E1BGG5",
                "type": "external"
            }
        ],
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        "length": 482,
        "protein_name": "Solute carrier family 36 member 2",
        "gene_name": "SLC36A2",
        "organism": "Bovine",
        "refseq_name": "proton-coupled amino acid transporter 2",
        "refseq_ac": [
            {
                "id": "NP_001193109",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193109",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "SLC36A2",
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        "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005681 spliceosomal complex;GO:0071013 catalytic step 2 spliceosome;GO:0071006 U2-type catalytic step 1 spliceosome;GO:0005682 U5 snRNP",
        "go_biological_process": "GO:0000388 spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)",
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        "filter_code": "0000000.0000001.010000.010000000000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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            {
                "id": "E1BH89_BOVIN",
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            }
        ],
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        "length": 822,
        "protein_name": "DNA replication licensing factor MCM6",
        "gene_name": "MCM6",
        "organism": "Bovine",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "MCM6",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "DNA replication licensing factor MCM6; 3.6.4.12",
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
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        "secondary_ac_list": "",
        "ec_number_list": [
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                "id": "3.6.4.12",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12",
                "type": "external"
            },
            {
                "id": "5.6.2.4",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4",
                "type": "external"
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            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13",
                "type": "external"
            },
            {
                "id": "2.3.2.27",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27",
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            },
            {
                "id": "7.2.2.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-",
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                "id": "2.7.7.49",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5",
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            },
            {
                "id": "2.7.7.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.-",
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            },
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                "id": "3.6.4.6",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6",
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            },
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10",
                "type": "external"
            },
            {
                "id": "5.6.2.3",
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            },
            {
                "id": "3.6.5.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-",
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            },
            {
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            },
            {
                "id": "3.6.4.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-",
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            {
                "id": "2.7.11.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1",
                "type": "external"
            },
            {
                "id": "3.1.-.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-",
                "type": "external"
            },
            {
                "id": "4.2.99.18",
                "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18",
                "type": "external"
            },
            {
                "id": "5.6.1.6",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6",
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            },
            {
                "id": "3.6.1.15",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15",
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            },
            {
                "id": "7.6.2.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.1",
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            },
            {
                "id": "3.1.3.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1",
                "type": "external"
            },
            {
                "id": "3.9.1.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.9.1.1",
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            {
                "id": "5.6.2.5",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5",
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            },
            {
                "id": "3.4.24.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-",
                "type": "external"
            },
            {
                "id": "3.6.-.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-",
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            },
            {
                "id": "3.6.1.-",
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            },
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                "id": "5.6.1.7",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.7",
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            },
            {
                "id": "3.1.4.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-",
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            },
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                "id": "3.4.21.53",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53",
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                "id": "2.7.11.22",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0016887 ATP hydrolysis activity;GO:0003697 single-stranded DNA binding;GO:0003678 DNA helicase activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005694 chromosome;GO:0042555 MCM complex",
        "go_biological_process": "GO:0006270 DNA replication initiation;GO:0000727 double-strand break repair via break-induced replication;GO:1902969 mitotic DNA replication",
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    },
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            {
                "id": "E1BHC1_BOVIN",
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            }
        ],
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        "length": 208,
        "protein_name": "Fibroblast growth factor",
        "gene_name": "FGF6",
        "organism": "Bovine",
        "refseq_name": "fibroblast growth factor 6 precursor",
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            {
                "id": "NP_001179329",
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            }
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        "gene_names_refseq": "FGF6; FGF7B",
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        "pathway": " (bta:540317);  (R-BTA-109704);  (R-BTA-1257604);  (R-BTA-190322);  (R-BTA-190373);  (R-BTA-190375);  (R-BTA-5654219);  (R-BTA-5654221);  (R-BTA-5654228);  (R-BTA-5654687);  (R-BTA-5654688);  (R-BTA-5654689);  (R-BTA-5654693);  (R-BTA-5654695);  (R-BTA-5654699);  (R-BTA-5654700);  (R-BTA-5654712);  (R-BTA-5654719);  (R-BTA-5654720);  (R-BTA-5654726);  (R-BTA-5654727);  (R-BTA-5654733);  (R-BTA-5673001);  (R-BTA-6811558)",
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        "go_molecular_function": "GO:0008083 growth factor activity;GO:0005104 fibroblast growth factor receptor binding",
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        "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0043410 positive regulation of MAPK cascade;GO:0051781 positive regulation of cell division;GO:0030334 regulation of cell migration;GO:0022008 neurogenesis",
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            {
                "id": "E1BHN6_BOVIN",
                "url": "https://www.uniprot.org/uniprot/E1BHN6",
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        ],
        "mass": 71003.0,
        "length": 636,
        "protein_name": "Polypeptide N-acetylgalactosaminyltransferase",
        "gene_name": "GALNT15",
        "organism": "Bovine",
        "refseq_name": "",
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        "protein_names_uniprotkb": "Polypeptide N-acetylgalactosaminyltransferase; 2.4.1.-; Protein-UDP acetylgalactosaminyltransferase",
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        "function": "Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Although it displays a much weaker activity toward all substrates tested compared to GALNT2, it is able to transfer up to seven GalNAc residues to the Muc5AC peptide, suggesting that it can fill vicinal Thr/Ser residues in cooperation with other GALNT proteins. Prefers Muc1a as substrate., [UniProtKB, UniProtKB]",
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                "type": "external"
            },
            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.41",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0046872 metal ion binding;GO:0030246 carbohydrate binding;GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity",
        "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0030133 transport vesicle",
        "go_biological_process": "GO:0006493 protein O-linked glycosylation",
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    },
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                "type": "external"
            }
        ],
        "mass": 95052.0,
        "length": 875,
        "protein_name": "Growth arrest specific 2 like 2",
        "gene_name": "GAS2L2",
        "organism": "Bovine",
        "refseq_name": "GAS2-like protein 2",
        "refseq_ac": [
            {
                "id": "NP_001192571",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192571",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "GAS2L2",
        "gene_names_refseq": "GAS2L2",
        "protein_names_uniprotkb": "Growth arrest specific 2 like 2",
        "protein_names_refseq": "GAS2-like protein 2",
        "tax_id": 9913,
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        "pathway": " (bta:539169)",
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        "go_molecular_function": "GO:0008017 microtubule binding;GO:0051015 actin filament binding;GO:0008093 cytoskeletal anchor activity;GO:0001965 G-protein alpha-subunit binding",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005884 actin filament;GO:0005886 plasma membrane;GO:0001725 stress fiber;GO:0036064 ciliary basal body",
        "go_biological_process": "GO:0031110 regulation of microtubule polymerization or depolymerization;GO:0045745 positive regulation of G protein-coupled receptor signaling pathway;GO:0007026 negative regulation of microtubule depolymerization;GO:0051764 actin crosslink formation;GO:0060296 regulation of cilium beat frequency involved in ciliary motility",
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        ],
        "mass": 59735.0,
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        "protein_name": "Transmembrane protein 108",
        "gene_name": "TMEM108",
        "organism": "Bovine",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "TMEM108",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Transmembrane protein 108",
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        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005769 early endosome;GO:0014069 postsynaptic density;GO:0030424 axon;GO:0010008 endosome membrane",
        "go_biological_process": "GO:0008090 retrograde axonal transport;GO:1990416 cellular response to brain-derived neurotrophic factor stimulus;GO:0098815 modulation of excitatory postsynaptic potential;GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway;GO:0006898 receptor-mediated endocytosis",
        "synthesized_glycan_count": 0,
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        "kg_view_protein": true
    },
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            {
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        ],
        "mass": 79289.0,
        "length": 694,
        "protein_name": "LARGE xylosyl- and glucuronyltransferase 2",
        "gene_name": "LARGE2",
        "organism": "Bovine",
        "refseq_name": "xylosyl- and glucuronyltransferase LARGE2 isoform X2",
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            {
                "id": "XP_005216506",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005216506",
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        "protein_names_uniprotkb": "LARGE xylosyl- and glucuronyltransferase 2",
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        "pathway": " (R-BTA-9939291)",
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        "ec_number_list": [],
        "go_molecular_function": "GO:0042285 xylosyltransferase activity;GO:0046872 metal ion binding;GO:0015020 glucuronosyltransferase activity",
        "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus",
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            {
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            }
        ],
        "mass": 39705.0,
        "length": 388,
        "protein_name": "Homeobox A13",
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            {
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            }
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        "protein_names_refseq": "homeobox protein Hox-A13",
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        "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific",
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        ],
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        "protein_name": "Hemojuvelin",
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            {
                "id": "NP_001193843",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193843",
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        ],
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        "gene_names_refseq": "HFE2; HJV",
        "protein_names_uniprotkb": "Hemojuvelin; Hemojuvelin BMP coreceptor; RGM domain family member C",
        "protein_names_refseq": "hemochromatosis type 2 (juvenile); hemojuvelin precursor",
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        "function": "Acts as a bone morphogenetic protein (BMP) coreceptor. Through enhancement of BMP signaling regulates hepcidin (HAMP) expression and regulates iron homeostasis., [UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0015026 coreceptor activity;GO:0036122 BMP binding",
        "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0098552 side of membrane",
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        ],
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        "protein_name": "Octanoyl-[acyl-carrier-protein]:protein N-octanoyltransferase LIPT2, mitochondrial",
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        "refseq_name": "octanoyl-[acyl-carrier-protein]:protein N-octanoyltransferase LIPT2, mitochondrial",
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            {
                "id": "NP_001192873",
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            }
        ],
        "gene_names_uniprotkb": "LIPT2",
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        "protein_names_uniprotkb": "Octanoyl-[acyl-carrier-protein]:protein N-octanoyltransferase LIPT2, mitochondrial; 2.3.1.181",
        "protein_names_refseq": "lipoyl(octanoyl) transferase 2 (putative); octanoyl-[acyl-carrier-protein]:protein N-octanoyltransferase LIPT2, mitochondrial",
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        "function": "Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate., [UniProtKB, UniProtKB]",
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                "id": "3.1.11.-",
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                "id": "2.7.13.3",
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            },
            {
                "id": "2.7.4.18",
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            {
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            {
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        "function": "Independently of its dipeptidase activity, acts as an adhesion receptor for neutrophil recruitment from bloodstream into inflamed lungs and liver., [UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:0097381 photoreceptor disc membrane;GO:0042622 photoreceptor outer segment membrane",
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    },
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            {
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            }
        ],
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        "go_cellular_component": "GO:0005790 smooth endoplasmic reticulum;GO:0005886 plasma membrane;GO:0043198 dendritic shaft;GO:0005789 endoplasmic reticulum membrane;GO:0030314 junctional membrane complex",
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        "function": "Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens., [UniProtKB, UniProtKB]",
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        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "ARID5B",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "AT-rich interactive domain-containing protein 5B; ARID domain-containing protein 5B",
        "protein_names_refseq": "",
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        "function": "Transcription coactivator that binds to the 5'-AATA[CT]-3' core sequence and plays a key role in adipogenesis and liver development. Acts by forming a complex with phosphorylated PHF2, which mediates demethylation at Lys-340, leading to target the PHF2-ARID5B complex to target promoters, where PHF2 mediates demethylation of dimethylated 'Lys-9' of histone H3 (H3K9me2), followed by transcription activation of target genes. The PHF2-ARID5B complex acts as a coactivator of HNF4A in liver. Required for adipogenesis: regulates triglyceride metabolism in adipocytes by regulating expression of adipogenic genes. Overexpression leads to induction of smooth muscle marker genes, suggesting that it may also act as a regulator of smooth muscle cell differentiation and proliferation (By similarity)., [UniProtKB]",
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        "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0000976 transcription cis-regulatory region binding",
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    },
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            {
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        ],
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        "protein_name": "Carboxypeptidase D",
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        "organism": "Bovine",
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            {
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            }
        ],
        "gene_names_uniprotkb": "CPD",
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        "protein_names_refseq": "carboxypeptidase D",
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        "pathway": " (bta:532189);  (R-BTA-432722);  (R-BTA-9696264);  (R-BTA-9696273)",
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        "function": "Functions in the processing of proteins and peptides in the secretory pathway. Mechanistically, cleaves exclusively C-terminal basic residues. By removing terminal residues, can modulate the activity, stability, and receptor-binding properties of bioactive peptides., [UniProtKB, UniProtKB]",
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                "type": "external"
            },
            {
                "id": "2.7.1.137",
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            },
            {
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            },
            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1",
                "type": "external"
            },
            {
                "id": "3.1.3.48",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48",
                "type": "external"
            },
            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.17.22",
                "type": "external"
            },
            {
                "id": "2.7.11.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1",
                "type": "external"
            },
            {
                "id": "3.6.4.13",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13",
                "type": "external"
            },
            {
                "id": "3.6.5.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2",
                "type": "external"
            },
            {
                "id": "2.7.3.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.3.2",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004181 metallocarboxypeptidase activity",
        "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane",
        "go_biological_process": "GO:0016485 protein processing;GO:0006518 peptide metabolic process",
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        "hit_score": 0.1,
        "record_id": "E1BLR9-1",
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        "filter_code": "0000000.0000001.010000.010000000000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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            {
                "id": "E1BLT5_BOVIN",
                "url": "https://www.uniprot.org/uniprot/E1BLT5",
                "type": "external"
            }
        ],
        "mass": 140812.0,
        "length": 1279,
        "protein_name": "Phosphatidylcholine translocator ABCB4",
        "gene_name": "ABCB4",
        "organism": "Bovine",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "ABCB4",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Phosphatidylcholine translocator ABCB4; 7.6.2.1; ATP-binding cassette sub-family B member 4; Multidrug resistance protein 3; p-glycoprotein 3",
        "protein_names_refseq": "",
        "tax_id": 9913,
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            {
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                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0005524 ATP binding;GO:0042626 ATPase-coupled transmembrane transporter activity;GO:0016887 ATP hydrolysis activity;GO:0090554 phosphatidylcholine floppase activity;GO:0140359 ABC-type transporter activity",
        "go_cellular_component": "GO:0005829 cytosol;GO:0045121 membrane raft;GO:0016324 apical plasma membrane;GO:0030136 clathrin-coated vesicle;GO:0016020 membrane",
        "go_biological_process": "GO:0055088 lipid homeostasis;GO:0045332 phospholipid translocation;GO:0061092 positive regulation of phospholipid translocation;GO:0032376 positive regulation of cholesterol transport;GO:1903413 cellular response to bile acid",
        "synthesized_glycan_count": 0,
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E1BLU3-1",
        "uniprot_id": [
            {
                "id": "E1BLU3_BOVIN",
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                "type": "external"
            }
        ],
        "mass": 56650.0,
        "length": 494,
        "protein_name": "Gap junction protein",
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        "organism": "Bovine",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "GJA10",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Gap junction protein",
        "protein_names_refseq": "",
        "tax_id": 9913,
        "disease": "",
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        "function": "Structural component of the gap junction, a specialized intercellular structure consisting of a cluster of closely packed pairs of transmembrane channels, the connexons, that allow passage of small molecules and electrical signals between neighboring cells. Forms homotypic and heterotypic channels gated by transjunctional voltage. Involved in intercellular innate immune signaling. Mediates translocation of 2',3'-cGAMP and 2',5'-oligoadenylates (2-5A) second messengers from virus-infected cells to macrophages and uninfected neighboring cells to propagate and amplify the antiviral immune response., [UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0005243 gap junction channel activity",
        "go_cellular_component": "GO:0005922 connexin complex",
        "go_biological_process": "GO:0007267 cell-cell signaling",
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        "filter_code": "0000000.0000001.100000.010000000000000000.0000000000000.000.00000",
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    },
    {
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            {
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                "type": "external"
            }
        ],
        "mass": 81028.0,
        "length": 709,
        "protein_name": "Ubiquitin carboxyl-terminal hydrolase",
        "gene_name": "USP44",
        "organism": "Bovine",
        "refseq_name": "ubiquitin carboxyl-terminal hydrolase 44",
        "refseq_ac": [
            {
                "id": "NP_001192766",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192766",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "USP44",
        "gene_names_refseq": "USP44",
        "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase; 3.4.19.12",
        "protein_names_refseq": "ubiquitin carboxyl-terminal hydrolase 44",
        "tax_id": 9913,
        "disease": "",
        "pathway": " (bta:517022);  (R-BTA-5689880)",
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        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 2,
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12",
                "type": "external"
            }
        ],
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        "go_cellular_component": "GO:0005737 cytoplasm;GO:0001650 fibrillar center",
        "go_biological_process": "GO:0007059 chromosome segregation;GO:0016579 protein deubiquitination;GO:0051301 cell division;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint",
        "synthesized_glycan_count": 0,
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        "kg_view_protein": true
    },
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                "type": "external"
            }
        ],
        "mass": 47283.0,
        "length": 426,
        "protein_name": "Purine nucleoside phosphorylase LACC1",
        "gene_name": "LACC1",
        "organism": "Bovine",
        "refseq_name": "purine nucleoside phosphorylase LACC1",
        "refseq_ac": [
            {
                "id": "NP_001193037",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193037",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LACC1",
        "gene_names_refseq": "C12H13orf31; LACC1",
        "protein_names_uniprotkb": "Purine nucleoside phosphorylase LACC1; 2.4.2.1; 2.4.2.28; 3.5.4.4; Adenosine deaminase LACC1; Fatty acid metabolism-immunity nexus; Guanosine phosphorylase LACC1; Isocyanic acid synthase; Laccase domain-containing protein 1; S-methyl-5'-thioadenosine phosphorylase LACC1",
        "protein_names_refseq": "laccase (multicopper oxidoreductase) domain containing 1; purine nucleoside phosphorylase LACC1",
        "tax_id": 9913,
        "disease": "",
        "pathway": " (bta:537649)",
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        "missing_score": 10000,
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        "ec_number_list": [
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.28",
                "type": "external"
            },
            {
                "id": "3.5.4.4",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.4",
                "type": "external"
            },
            {
                "id": "2.4.2.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.1",
                "type": "external"
            }
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    },
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            {
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            {
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        "function": "Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2. In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Phosphorylates PPP1R12A. In concert with FAM89B/LRAP25 mediates the targeting of LIMK1 to the lamellipodium resulting in its activation and subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation., [UniProtKB, UniProtKB, UniProtKB]",
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                "type": "external"
            },
            {
                "id": "2.7.11.26",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26",
                "type": "external"
            },
            {
                "id": "2.7.11.21",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21",
                "type": "external"
            },
            {
                "id": "2.7.1.153",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153",
                "type": "external"
            },
            {
                "id": "2.7.1.137",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137",
                "type": "external"
            },
            {
                "id": "2.7.1.154",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154",
                "type": "external"
            },
            {
                "id": "4.1.1.32",
                "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32",
                "type": "external"
            },
            {
                "id": "2.7.11.38",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38",
                "type": "external"
            },
            {
                "id": "2.7.11.11",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11",
                "type": "external"
            },
            {
                "id": "3.1.11.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-",
                "type": "external"
            },
            {
                "id": "2.7.4.6",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6",
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            },
            {
                "id": "2.7.13.3",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3",
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            },
            {
                "id": "2.7.4.18",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.18",
                "type": "external"
            },
            {
                "id": "3.1.24.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.24.-",
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            },
            {
                "id": "3.6.5.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2",
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            },
            {
                "id": "2.7.11.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-",
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            },
            {
                "id": "2.7.11.4",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.4",
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            },
            {
                "id": "2.7.2.3",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3",
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            },
            {
                "id": "2.7.11.10",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0044877 protein-containing complex binding",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0030027 lamellipodium;GO:0042641 actomyosin",
        "go_biological_process": "GO:0016477 cell migration;GO:0031032 actomyosin structure organization",
        "synthesized_glycan_count": 0,
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        "record_id": "E1BP72-1",
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    },
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            {
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            }
        ],
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            {
                "id": "NP_001178270",
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            }
        ],
        "gene_names_uniprotkb": "GUCY1A2",
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        "class_list": "",
        "function": "Has guanylyl cyclase on binding to the beta-1 subunit., [UniProtKB, UniProtKB]",
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            {
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                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0004383 guanylate cyclase activity;GO:0005525 GTP binding;GO:0020037 heme binding",
        "go_cellular_component": "GO:0008074 guanylate cyclase complex, soluble",
        "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0070482 response to oxygen levels",
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    {
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            {
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        ],
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        "organism": "Bovine",
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            {
                "id": "XP_002684924",
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            }
        ],
        "gene_names_uniprotkb": "EIF2B5",
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        "protein_names_refseq": "translation initiation factor eIF2B subunit epsilon",
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                "id": "2.7.10.1",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17",
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                "id": "2.7.11.39",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39",
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                "id": "2.7.1.150",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150",
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                "id": "2.7.11.21",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21",
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                "id": "2.7.1.153",
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                "id": "2.7.1.137",
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                "id": "2.7.1.154",
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            {
                "id": "4.1.1.32",
                "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32",
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            {
                "id": "2.7.11.38",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38",
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                "id": "3.1.11.-",
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                "id": "2.7.11.-",
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                "id": "2.7.11.10",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10",
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            }
        ],
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        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005634 nucleus",
        "go_biological_process": "GO:1902018 negative regulation of cilium assembly;GO:0032956 regulation of actin cytoskeleton organization;GO:1900026 positive regulation of substrate adhesion-dependent cell spreading;GO:0090521 podocyte cell migration;GO:1900182 positive regulation of protein localization to nucleus",
        "synthesized_glycan_count": 0,
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        "kg_view_protein": true
    },
    {
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        ],
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            {
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        ],
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        "function": "Catalyzes the first and rate limiting step of the catabolism of tryptophan along the kynurenine pathway. Involved in immune regulation., [UniProtKB, UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:0005737 cytoplasm",
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        "function": "Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly (By similarity)., [UniProtKB]",
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        "protein_name": "G protein-coupled receptor family C group 6 member A",
        "gene_name": "GPRC6A",
        "organism": "Bovine",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "GPRC6A",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "G protein-coupled receptor family C group 6 member A",
        "protein_names_refseq": "",
        "tax_id": 9913,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "Receptor activated by multiple ligands, including osteocalcin (BGLAP), basic amino acids, and various cations. Activated by amino acids with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine but also by small and polar amino acids. The L-alpha amino acids respond is augmented by divalent cations Ca(2+) and Mg(2+). Seems to act through a G(q)/G(11) and G(i)-coupled pathway. Regulates testosterone production by acting as a ligand for uncarboxylated osteocalcin hormone: osteocalcin-binding at the surface of Leydig cells initiates a signaling response that promotes the expression of enzymes required for testosterone synthesis in a CREB-dependent manner. Mediates the non-genomic effects of androgens in multiple tissue. May coordinate nutritional and hormonal anabolic signals through the sensing of extracellular amino acids, osteocalcin, divalent ions and its responsiveness to anabolic steroids., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 4,
        "predicted_n_glycosites": 4,
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        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_s_glycosites": 0,
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        "reported_c_glycosites_with_glycan": 0,
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        "total_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "disease_count": 0,
        "glyco_site_count": 4,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0004930 G protein-coupled receptor activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:2000224 regulation of testosterone biosynthetic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "E1BPQ3-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.010000000000000000.0000000010000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E1BPS6-1",
        "uniprot_id": [
            {
                "id": "E1BPS6_BOVIN",
                "url": "https://www.uniprot.org/uniprot/E1BPS6",
                "type": "external"
            }
        ],
        "mass": 296909.0,
        "length": 2789,
        "protein_name": "Multiple epidermal growth factor-like domains protein 8",
        "gene_name": "MEGF8",
        "organism": "Bovine",
        "refseq_name": "multiple epidermal growth factor-like domains protein 8",
        "refseq_ac": [
            {
                "id": "XP_024834866",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024834866",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "MEGF8",
        "gene_names_refseq": "MEGF8",
        "protein_names_uniprotkb": "Multiple epidermal growth factor-like domains protein 8; Epidermal growth factor-like protein 4",
        "protein_names_refseq": "multiple epidermal growth factor-like domains protein 8",
        "tax_id": 9913,
        "disease": "",
        "pathway": " (bta:615688)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "Acts as a negative regulator of hedgehog signaling., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 5,
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        "reported_phosphosites": 0,
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        "reported_snv": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "glyco_site_count": 5,
        "binding_glycan_count": 0,
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        "ec_number_list": [],
        "go_molecular_function": "GO:0005509 calcium ion binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0016020 membrane;GO:0000151 ubiquitin ligase complex",
        "go_biological_process": "GO:0060971 embryonic heart tube left/right pattern formation;GO:0097094 craniofacial suture morphogenesis;GO:0030326 embryonic limb morphogenesis;GO:0030509 BMP signaling pathway;GO:0042074 cell migration involved in gastrulation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "E1BPS6-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.010000.010000000000000000.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E1BPT2-1",
        "uniprot_id": [
            {
                "id": "E1BPT2_BOVIN",
                "url": "https://www.uniprot.org/uniprot/E1BPT2",
                "type": "external"
            }
        ],
        "mass": 57118.0,
        "length": 523,
        "protein_name": "Equilibrative nucleoside transporter 4",
        "gene_name": "SLC29A4",
        "organism": "Bovine",
        "refseq_name": "equilibrative nucleoside transporter 4 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_010817904",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010817904",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "SLC29A4",
        "gene_names_refseq": "SLC29A4",
        "protein_names_uniprotkb": "Equilibrative nucleoside transporter 4; Plasma membrane monoamine transporter; Solute carrier family 29 member 4",
        "protein_names_refseq": "equilibrative nucleoside transporter 4 isoform X1",
        "tax_id": 9913,
        "disease": "",
        "pathway": " (R-BTA-83936)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "",
        "predicted_glycosites": 1,
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        "predicted_s_glycosites": 0,
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        "mined_s_glycosites": 0,
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        "reported_c_glycosites_with_glycan": 0,
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        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
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        "biomarker_type": "",
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        "glyco_site_count": 1,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005326 neurotransmitter transmembrane transporter activity;GO:0008324 monoatomic cation transmembrane transporter activity;GO:0015562 efflux transmembrane transporter activity;GO:0005337 nucleoside transmembrane transporter activity;GO:0008504 monoamine transmembrane transporter activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane;GO:0098793 presynapse",
        "go_biological_process": "GO:0051615 histamine uptake;GO:0090494 dopamine uptake;GO:0051610 serotonin uptake;GO:0048241 epinephrine transport;GO:0042908 xenobiotic transport",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "E1BPT2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.010000000000000000.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E1BPT8-1",
        "uniprot_id": [
            {
                "id": "E1BPT8_BOVIN",
                "url": "https://www.uniprot.org/uniprot/E1BPT8",
                "type": "external"
            }
        ],
        "mass": 244369.0,
        "length": 2332,
        "protein_name": "Neurogenic locus notch homolog protein 3",
        "gene_name": "NOTCH3",
        "organism": "Bovine",
        "refseq_name": "neurogenic locus notch homolog protein 3",
        "refseq_ac": [
            {
                "id": "XP_003586294",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586294",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "NOTCH3",
        "gene_names_refseq": "NOTCH3",
        "protein_names_uniprotkb": "Neurogenic locus notch homolog protein 3",
        "protein_names_refseq": "neurogenic locus notch homolog protein 3",
        "tax_id": 9913,
        "disease": "",
        "pathway": " (bta:789485)",
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        "class_list": "",
        "function": "Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in bone remodeling and homeostasis. In collaboration with RELA/p65 enhances NFATc1 promoter activity and positively regulates RANKL-induced osteoclast differentiation. Positively regulates self-renewal of liver cancer cells., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
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        "missing_score": 10000,
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        "ec_number_list": [],
        "go_molecular_function": "GO:0042802 identical protein binding;GO:0005509 calcium ion binding;GO:0038023 signaling receptor activity",
        "go_cellular_component": "GO:0005576 extracellular region;GO:0005654 nucleoplasm;GO:0005886 plasma membrane;GO:0043235 receptor complex;GO:0005770 late endosome",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007219 Notch signaling pathway;GO:0008284 positive regulation of cell population proliferation;GO:0016358 dendrite development;GO:0045944 positive regulation of transcription by RNA polymerase II",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "E1BPT8-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.010000.010000000000000000.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E1BPW1-1",
        "uniprot_id": [
            {
                "id": "E1BPW1_BOVIN",
                "url": "https://www.uniprot.org/uniprot/E1BPW1",
                "type": "external"
            }
        ],
        "mass": 89137.0,
        "length": 808,
        "protein_name": "Oxysterol-binding protein",
        "gene_name": "OSBP",
        "organism": "Bovine",
        "refseq_name": "oxysterol-binding protein 1",
        "refseq_ac": [
            {
                "id": "NP_001192899",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192899",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "OSBP",
        "gene_names_refseq": "OSBP",
        "protein_names_uniprotkb": "Oxysterol-binding protein",
        "protein_names_refseq": "oxysterol-binding protein 1",
        "tax_id": 9913,
        "disease": "",
        "pathway": " (bta:530000);  (R-BTA-1660661);  (R-BTA-192105)",
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        "class_list": "",
        "function": "",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0019904 protein domain specific binding;GO:0070273 phosphatidylinositol-4-phosphate binding;GO:0032934 sterol binding;GO:0120015 sterol transfer activity",
        "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0097038 perinuclear endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane",
        "go_biological_process": "GO:0006686 sphingomyelin biosynthetic process;GO:0035627 ceramide transport;GO:0015914 phospholipid transport;GO:0032367 intracellular cholesterol transport",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "E1BPW1-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.010000000000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E1BPY8-1",
        "uniprot_id": [
            {
                "id": "E1BPY8_BOVIN",
                "url": "https://www.uniprot.org/uniprot/E1BPY8",
                "type": "external"
            }
        ],
        "mass": 353091.0,
        "length": 3133,
        "protein_name": "DNA polymerase zeta catalytic subunit",
        "gene_name": "REV3L",
        "organism": "Bovine",
        "refseq_name": "DNA polymerase zeta catalytic subunit",
        "refseq_ac": [
            {
                "id": "NP_001193101",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193101",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "REV3L",
        "gene_names_refseq": "REV3L",
        "protein_names_uniprotkb": "DNA polymerase zeta catalytic subunit; 2.7.7.7; Protein reversionless 3-like",
        "protein_names_refseq": "DNA polymerase zeta catalytic subunit; REV3-like, catalytic subunit of DNA polymerase zeta; REV3-like, polymerase (DNA directed), zeta, catalytic subunit",
        "tax_id": 9913,
        "disease": "",
        "pathway": " (bta:517422);  (R-BTA-5655862);  (R-BTA-5656121)",
        "pathway_count": 3,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "Catalytic subunit of the DNA polymerase zeta complex, an error-prone polymerase specialized in translesion DNA synthesis (TLS). Lacks an intrinsic 3'-5' exonuclease activity and thus has no proofreading function., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 2,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 2,
        "predicted_c_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": [
            {
                "id": "2.7.7.7",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7",
                "type": "external"
            },
            {
                "id": "2.7.7.49",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49",
                "type": "external"
            },
            {
                "id": "3.6.4.12",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12",
                "type": "external"
            },
            {
                "id": "2.7.7.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.-",
                "type": "external"
            },
            {
                "id": "2.7.7.31",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.31",
                "type": "external"
            },
            {
                "id": "3.1.11.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-",
                "type": "external"
            },
            {
                "id": "2.7.7.102",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.102",
                "type": "external"
            },
            {
                "id": "4.2.99.18",
                "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18",
                "type": "external"
            },
            {
                "id": "4.2.99.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.-",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0003887 DNA-directed DNA polymerase activity;GO:0003677 DNA binding;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0000166 nucleotide binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0016035 zeta DNA polymerase complex;GO:0090734 site of DNA damage",
        "go_biological_process": "GO:0000724 double-strand break repair via homologous recombination;GO:0042276 error-prone translesion synthesis",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
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        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "ec_number_list": [
            {
                "id": "1.14.18.1",
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            },
            {
                "id": "1.14.18.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.18.-",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0046872 metal ion binding;GO:0004503 tyrosinase activity",
        "go_cellular_component": "GO:0030669 clathrin-coated endocytic vesicle membrane;GO:0042470 melanosome;GO:0010008 endosome membrane;GO:0033162 melanosome membrane",
        "go_biological_process": "GO:0032438 melanosome organization;GO:0042438 melanin biosynthetic process;GO:0048023 positive regulation of melanin biosynthetic process;GO:0030318 melanocyte differentiation",
        "synthesized_glycan_count": 0,
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    },
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            {
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        "refseq_name": "",
        "refseq_ac": [],
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        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Tyrosinase; 1.14.18.1; Monophenol monooxygenase",
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        "pathway": " (R-BTA-5662702)",
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        "function": "This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone., [UniProtKB, UniProtKB]",
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            },
            {
                "id": "1.14.18.-",
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            }
        ],
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        "go_cellular_component": "GO:0048471 perinuclear region of cytoplasm;GO:0042470 melanosome;GO:0033162 melanosome membrane",
        "go_biological_process": "GO:0043473 pigmentation;GO:0042438 melanin biosynthetic process;GO:0009637 response to blue light",
        "synthesized_glycan_count": 0,
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    },
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        ],
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        "refseq_name": "E3 ubiquitin-protein ligase SIAH2",
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            {
                "id": "NP_001193983",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193983",
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            }
        ],
        "gene_names_uniprotkb": "SIAH2",
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        "function": "E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates., [UniProtKB, UniProtKB]",
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            {
                "id": "2.3.2.-",
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                "id": "2.3.2.25",
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        ],
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        "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol",
        "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0016567 protein ubiquitination;GO:0042752 regulation of circadian rhythm;GO:0048511 rhythmic process;GO:0060070 canonical Wnt signaling pathway",
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                "id": "2.7.11.25",
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                "id": "2.7.11.22",
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                "id": "2.7.10.2",
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                "id": "2.7.1.154",
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                "id": "4.1.1.32",
                "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32",
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            {
                "id": "2.7.11.38",
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                "id": "2.7.11.11",
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                "id": "3.1.11.-",
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            {
                "id": "2.7.4.6",
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                "id": "3.1.24.-",
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                "id": "2.7.11.-",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3",
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                "id": "4.2.99.18",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10",
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            }
        ],
        "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0030688 preribosome, small subunit precursor",
        "go_biological_process": "GO:2000234 positive regulation of rRNA processing;GO:0030071 regulation of mitotic metaphase/anaphase transition;GO:2000208 positive regulation of ribosomal small subunit export from nucleus;GO:0030490 maturation of SSU-rRNA",
        "synthesized_glycan_count": 0,
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        "record_id": "F1MBN7-1",
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        "kg_view_protein": true
    },
    {
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        ],
        "mass": 35090.0,
        "length": 318,
        "protein_name": "Ubiquitin-conjugating enzyme E2 J1",
        "gene_name": "UBE2J1",
        "organism": "Bovine",
        "refseq_name": "ubiquitin-conjugating enzyme E2 J1",
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            {
                "id": "NP_001193115",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193115",
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        "protein_names_refseq": "non-canonical ubquitin conjugating enzyme 1; ubiquitin-conjugating enzyme E2 J1; ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast); ubiquitin-conjugating enzyme E2, J1, U",
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        "function": "Catalyzes the covalent attachment of ubiquitin to other proteins. Functions in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD) and is essential for cells to recover from ER stress. Plays a role in MAPKAPK2-dependent translational control of TNF synthesis. Also acts as a platform for perinuclear positioning of the endosomal system by mediating ubiquitination of SQSTM1 through interaction with the E3 ubiquitin-protein ligase RNF26. Plays a role in male fecundity through the interaction with the E3 ubiquitin-protein ligase RNF133., [UniProtKB, UniProtKB]",
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        "function": "Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product., [UniProtKB, HAMAP]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [
            {
                "id": "2.4.2.64",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.64",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0046872 metal ion binding;GO:0008479 tRNA-guanosine(34) queuine transglycosylase activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0032473 cytoplasmic side of mitochondrial outer membrane;GO:0120507 tRNA-guanine transglycosylase complex",
        "go_biological_process": "GO:0002099 tRNA wobble guanine modification",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "F1MCU6-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.010000000000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "F1MCV8-1",
        "uniprot_id": [
            {
                "id": "F1MCV8_BOVIN",
                "url": "https://www.uniprot.org/uniprot/F1MCV8",
                "type": "external"
            }
        ],
        "mass": 16421.0,
        "length": 145,
        "protein_name": "Prolactin-inducible protein homolog",
        "gene_name": "PIP",
        "organism": "Bovine",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "PIP",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Prolactin-inducible protein homolog",
        "protein_names_refseq": "",
        "tax_id": 9913,
        "disease": "",
        "pathway": " (R-BTA-5223345)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0042802 identical protein binding;GO:0004190 aspartic-type endopeptidase activity;GO:0019864 IgG binding",
        "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus",
        "go_biological_process": "GO:0006508 proteolysis;GO:0010628 positive regulation of gene expression;GO:0002682 regulation of immune system process;GO:0070233 negative regulation of T cell apoptotic process;GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "F1MCV8-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.010000000000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "F1MCW8-1",
        "uniprot_id": [
            {
                "id": "F1MCW8_BOVIN",
                "url": "https://www.uniprot.org/uniprot/F1MCW8",
                "type": "external"
            }
        ],
        "mass": 107479.0,
        "length": 957,
        "protein_name": "Glutamate receptor",
        "gene_name": "GRIK4",
        "organism": "Bovine",
        "refseq_name": "glutamate receptor ionotropic, kainate 4 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_059730738",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059730738",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "GRIK4",
        "gene_names_refseq": "GRIK4",
        "protein_names_uniprotkb": "Glutamate receptor",
        "protein_names_refseq": "glutamate receptor ionotropic, kainate 4 isoform X1",
        "tax_id": 9913,
        "disease": "",
        "pathway": " (R-BTA-451308)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_o_glycosites": 0,
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        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
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        "reported_snv": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "disease_count": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0015277 kainate selective glutamate receptor activity;GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential;GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0042734 presynaptic membrane;GO:0032983 kainate selective glutamate receptor complex;GO:0098839 postsynaptic density membrane;GO:0098686 hippocampal mossy fiber to CA3 synapse",
        "go_biological_process": "GO:0035249 synaptic transmission, glutamatergic;GO:0050804 modulation of chemical synaptic transmission",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "F1MCW8-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.010000.010000000000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "F1MD77-1",
        "uniprot_id": [
            {
                "id": "F1MD77_BOVIN",
                "url": "https://www.uniprot.org/uniprot/F1MD77",
                "type": "external"
            }
        ],
        "mass": 177693.0,
        "length": 1608,
        "protein_name": "Laminin subunit gamma-1",
        "gene_name": "LAMC1",
        "organism": "Bovine",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "LAMC1",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Laminin subunit gamma-1",
        "protein_names_refseq": "",
        "tax_id": 9913,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
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        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
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        "reported_o_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005201 extracellular matrix structural constituent",
        "go_cellular_component": "GO:0005576 extracellular region;GO:0005604 basement membrane",
        "go_biological_process": "GO:0016477 cell migration;GO:0022617 extracellular matrix disassembly;GO:0009887 animal organ morphogenesis;GO:0034446 substrate adhesion-dependent cell spreading;GO:0007411 axon guidance",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "F1MD77-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.010000.010000000000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "F1MDA3-1",
        "uniprot_id": [
            {
                "id": "F1MDA3_BOVIN",
                "url": "https://www.uniprot.org/uniprot/F1MDA3",
                "type": "external"
            }
        ],
        "mass": 56849.0,
        "length": 515,
        "protein_name": "Y+L amino acid transporter 2",
        "gene_name": "SLC7A6",
        "organism": "Bovine",
        "refseq_name": "Y+L amino acid transporter 2",
        "refseq_ac": [
            {
                "id": "XP_010812819",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010812819",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "SLC7A6",
        "gene_names_refseq": "SLC7A6",
        "protein_names_uniprotkb": "Y+L amino acid transporter 2; Solute carrier family 7 member 6; y(+)L-type amino acid transporter 2",
        "protein_names_refseq": "Y+L amino acid transporter 2",
        "tax_id": 9913,
        "disease": "",
        "pathway": " (bta:530661);  (R-BTA-352230)",
        "pathway_count": 2,
        "publication_count": 0,
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        "class_list": "",
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0015179 L-amino acid transmembrane transporter activity;GO:0034618 arginine binding;GO:0106439 L-lysine:L-arginine antiporter activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0015820 L-leucine transport;GO:0031460 glycine betaine transport;GO:0003333 amino acid transmembrane transport;GO:0015822 ornithine transport;GO:0089718 amino acid import across plasma membrane",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "F1MDA3-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.010000000000000000.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "F1MDB2-1",
        "uniprot_id": [
            {
                "id": "SIM20_BOVIN",
                "url": "https://www.uniprot.org/uniprot/F1MDB2",
                "type": "external"
            }
        ],
        "mass": 7702.0,
        "length": 67,
        "protein_name": "Small integral membrane protein 20",
        "gene_name": "SMIM20",
        "organism": "Bovine",
        "refseq_name": "small integral membrane protein 20",
        "refseq_ac": [
            {
                "id": "NP_001138900",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138900",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "SMIM20; LOC101904614",
        "gene_names_refseq": "C6H4orf52; MITRAC7; SMIM20",
        "protein_names_uniprotkb": "Small integral membrane protein 20; MITRAC7; Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 7 kDa",
        "protein_names_refseq": "mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 7 kDa; small integral membrane protein 20",
        "tax_id": 9913,
        "disease": "",
        "pathway": " (bta:101904614);  (bta:615093);  (R-BTA-9864848)",
        "pathway_count": 3,
        "publication_count": 2,
        "publication_id_list": "19393038;22963497",
        "class_list": "",
        "function": "Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly (By similarity). Promotes the progression of complex assembly after the association of MT-CO1/COX1 with COX4I1 and COX6C (By similarity). Chaperone-like assembly factor required to stabilize newly synthesized MT-CO1/COX1 and to prevent its premature turnover (By similarity)., [UniProtKB, UniProtKB]; Peptide involved in a broad spectrum of regulatory functions (By similarity). Is a ligand for GPR173 (By similarity). As part of the reproductive cycle, it regulates gonadotropin-releasing hormone (GnRH) signaling in the hypothalamus and pituitary gland which augments the release of luteinizing hormone (By similarity). Plays a protective role in memory retention through activation of GNRHR (By similarity). Regulates the secretion of AVP by hypothalamic neurons (By similarity). Plays a role in the transduction of the itch sensation (By similarity). Induces anxiolytic effects, reducing behavior associated with anxiety (By similarity). Regulates food intake as well as satiation and satiety (By similarity). In the ovary, it regulates follicular growth by stimulating granulosa cell proliferation by increasing the expression of GPR173, CREB1, CYP19A1, KITLG, FSHR, and LHCGR (By similarity). It also increases the production of estradiol (E2) (By similarity). In the heart, it regulates contractility and relaxation (By similarity). It also plays a cardioprotective role during ischemia, where it activates the SAFE and RISK pathways (By similarity). Stimulates the proliferation and differentiation of preadipocytes (By similarity). In pancreatic islet cells, it induces proliferation of islet cells as well as the production of INS (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
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        "reported_c_glycosites": 0,
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        "biomarker_type": "",
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        "go_cellular_component": "GO:0005576 extracellular region;GO:0005743 mitochondrial inner membrane",
        "go_biological_process": "GO:0033617 mitochondrial respiratory chain complex IV assembly",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "F1MDB2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.010000000000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "F1MDK8-1",
        "uniprot_id": [
            {
                "id": "F1MDK8_BOVIN",
                "url": "https://www.uniprot.org/uniprot/F1MDK8",
                "type": "external"
            }
        ],
        "mass": 35654.0,
        "length": 323,
        "protein_name": "ADP/ATP translocase",
        "gene_name": "SLC25A31",
        "organism": "Bovine",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "SLC25A31",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "ADP/ATP translocase; ADP,ATP carrier protein",
        "protein_names_refseq": "",
        "tax_id": 9913,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "Catalyzes the exchange of ADP and ATP across the membrane., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "predicted_c_glycosites": 0,
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        "mined_glycosites": 0,
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        "mined_o_glycosites": 0,
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        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        ],
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        "function": "Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization., [UniProtKB, UniProtKB]",
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        "function": "Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling., [UniProtKB, UniProtKB]; Receptor for erythropoietin, which mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase., [UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0004900 erythropoietin receptor activity;GO:0042802 identical protein binding",
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        "protein_names_refseq": "multiple epidermal growth factor-like domains protein 10 isoform X1",
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        "go_molecular_function": "GO:0005044 scavenger receptor activity;GO:0005112 Notch binding;GO:0001849 complement component C1q complex binding",
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        "protein_name": "Iron-sulfur cluster assembly enzyme ISCU",
        "gene_name": "LOC533308",
        "organism": "Bovine",
        "refseq_name": "iron-sulfur cluster scaffold homolog (E. coli)-like",
        "refseq_ac": [
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        "gene_names_refseq": "LOC533308",
        "protein_names_uniprotkb": "Iron-sulfur cluster assembly enzyme ISCU; NifU-like N-terminal domain-containing protein; NifU-like protein",
        "protein_names_refseq": "iron-sulfur cluster scaffold homolog (E. coli)-like",
        "tax_id": 9913,
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        "pathway": " (bta:533308)",
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        "function": "Mitochondrial scaffold protein, of the core iron-sulfur cluster (ISC) assembly complex, that provides the structural architecture on which the [2Fe-2S] clusters are assembled. The core iron-sulfur cluster (ISC) assembly complex is involved in the de novo synthesis of a [2Fe-2S] cluster, the first step of the mitochondrial iron-sulfur protein biogenesis. This process is initiated by the cysteine desulfurase complex (NFS1:LYRM4:NDUFAB1) that produces persulfide which is delivered on the scaffold protein ISCU in a FXN-dependent manner. Then this complex is stabilized by FDX2 which provides reducing equivalents to accomplish the [2Fe-2S] cluster assembly. Finally, the [2Fe-2S] cluster is transferred from ISCU to chaperone proteins, including HSCB, HSPA9 and GLRX5. Exists as two slow interchanging conformational states, a structured (S) and disordered (D) form. May modulate NFS1 desulfurase activity in a zinc-dependent manner. Modulates the interaction between FXN and the cysteine desulfurase complex., [UniProtKB, UniProtKB]",
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        ],
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        "protein_name": "Integrin beta",
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        "refseq_name": "integrin beta-4 isoform 2 precursor",
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            {
                "id": "XP_024835565",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024835565",
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        "gene_names_uniprotkb": "ITGB4",
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        "protein_names_refseq": "integrin beta-4 isoform 2 precursor; integrin, beta 4",
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        "pathway": " (R-BTA-3000170);  (R-BTA-446107)",
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        ],
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        "protein_name": "Circadian locomoter output cycles protein kaput",
        "gene_name": "CLOCK",
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            {
                "id": "NP_001276698",
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        "protein_names_refseq": "circadian locomoter output cycles protein kaput; clock homolog",
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        "function": "The expression of CLOCK was significantly higher among good quality bull semen than motility-impaired ones., [RefSeq, PubMed]; The protein encoded by this gene plays a central role in the regulation of circadian rhythms. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and contains DNA binding histone acetyltransferase activity. The encoded protein forms a heterodimer with ARNTL (BMAL1) that binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Polymorphisms in this gene may be associated with behavioral changes in certain populations and with obesity and metabolic syndrome. [provided by RefSeq, Feb 2014]., [RefSeq]; These data provide a new insight that Per2 and Clock have different action on ovarian granulosa cell functions., [RefSeq, PubMed]",
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        "go_cellular_component": "GO:1990513 CLOCK-BMAL transcription complex;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005667 transcription regulator complex;GO:0005694 chromosome",
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        "protein_name": "Voltage-dependent T-type calcium channel subunit alpha",
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        "function": "Voltage-sensitive calcium channel that gives rise to T-type calcium currents. T-type calcium channels belong to the 'low-voltage activated (LVA)' group. A particularity of this type of channel is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons. In the adrenal zona glomerulosa, participates in the signaling pathway leading to aldosterone production in response to either AGT/angiotensin II, or hyperkalemia., [UniProtKB, UniProtKB, UniProtKB]; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the `low-voltage activated (LVA)` group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:0043005 neuron projection;GO:0005891 voltage-gated calcium channel complex;GO:0001518 voltage-gated sodium channel complex",
        "go_biological_process": "GO:0086010 membrane depolarization during action potential;GO:0045956 positive regulation of calcium ion-dependent exocytosis;GO:0070509 calcium ion import;GO:2000344 positive regulation of acrosome reaction;GO:0042391 regulation of membrane potential",
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        ],
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        "protein_name": "Mitochondrial tRNA-specific 2-thiouridylase 1",
        "gene_name": "TRMU",
        "organism": "Bovine",
        "refseq_name": "mitochondrial tRNA-specific 2-thiouridylase 1",
        "refseq_ac": [
            {
                "id": "NP_001156660",
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        "protein_names_uniprotkb": "Mitochondrial tRNA-specific 2-thiouridylase 1; 2.8.1.14",
        "protein_names_refseq": "mitochondrial tRNA-specific 2-thiouridylase 1; tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase",
        "tax_id": 9913,
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        "pathway": " (bta:616451)",
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        "function": "Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "go_cellular_component": "GO:0005739 mitochondrion",
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        "protein_name": "Cationic amino acid transporter C-terminal domain-containing protein",
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        "function": "Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs. Involved in the quality control and retention of unspliced mRNAs in the nucleus; in association with TPR, regulates the nuclear export of unspliced mRNA species bearing constitutive transport element (CTE) in a NXF1- and KHDRBS1-independent manner. Mediates TPR anchoring to the nuclear membrane at NPC. The repeat-containing domain may be involved in anchoring other components of the NPC to the pore membrane. Possible DNA-binding subunit of the nuclear pore complex (NPC)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "pathway": " (R-BTA-1251985);  (R-BTA-193692);  (R-BTA-205043);  (R-BTA-3928665);  (R-BTA-6798695);  (R-BTA-9839383)",
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        "function": "Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0051117 ATPase binding;GO:0070851 growth factor receptor binding;GO:0061133 endopeptidase activator activity;GO:0042500 aspartic endopeptidase activity, intramembrane cleaving",
        "go_cellular_component": "GO:0099503 secretory vesicle;GO:0005886 plasma membrane;GO:0005764 lysosome;GO:0012505 endomembrane system;GO:0030659 cytoplasmic vesicle membrane",
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        ],
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        "protein_name": "Protein Jade-1",
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        "refseq_name": "protein Jade-1 isoform X3",
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            {
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        ],
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                "id": "NP_001291951",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291951",
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            }
        ],
        "gene_names_uniprotkb": "MPPE1",
        "gene_names_refseq": "MPPE1",
        "protein_names_uniprotkb": "Metallophosphoesterase 1; Post-GPI attachment to proteins factor 5",
        "protein_names_refseq": "metallophosphoesterase 1",
        "tax_id": 9913,
        "disease": "",
        "pathway": " (bta:506830)",
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        "publication_id_list": "",
        "class_list": "",
        "function": "Metallophosphoesterase that catalyzes the removal of a side-chain ethanolamine-phosphate (EtNP) from the second mannose of the GPI-anchor protein intermediate. Participates in the glycan remodeling steps of GPI-anchor maturation to allow an efficient transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0046872 metal ion binding;GO:0008081 phosphoric diester hydrolase activity;GO:0016787 hydrolase activity",
        "go_cellular_component": "GO:0012505 endomembrane system;GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005794 Golgi apparatus;GO:0016020 membrane",
        "go_biological_process": "GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006506 GPI anchor biosynthetic process",
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    },
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            {
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            }
        ],
        "mass": 62335.0,
        "length": 568,
        "protein_name": "Omega-hydroxyceramide transacylase",
        "gene_name": "PNPLA1",
        "organism": "Bovine",
        "refseq_name": "omega-hydroxyceramide transacylase isoform X2",
        "refseq_ac": [
            {
                "id": "XP_059736446",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059736446",
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        ],
        "gene_names_uniprotkb": "PNPLA1",
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        "protein_names_uniprotkb": "Omega-hydroxyceramide transacylase; 2.3.1.296; Patatin-like phospholipase domain-containing protein 1",
        "protein_names_refseq": "omega-hydroxyceramide transacylase isoform X2",
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        "function": "Omega-hydroxyceramide transacylase involved in the synthesis of omega-O-acylceramides (esterified omega-hydroxyacyl-sphingosine; EOS), which are extremely hydrophobic lipids involved in skin barrier formation. Catalyzes the last step of the synthesis of omega-O-acylceramides by transferring linoleic acid from triglycerides to an omega-hydroxyceramide. Omega-O-acylceramides, are required for the biogenesis of lipid lamellae in the stratum corneum and the formation of the cornified lipid envelope which are essential for the epidermis barrier function. These lipids also play a role in keratinocyte differentiation. May also act on omega-hydroxylated ultra-long chain fatty acids (omega-OH ULCFA) and acylglucosylceramides (GlcEOS)., [UniProtKB, UniProtKB, UniProtKB]",
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        ],
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        "go_biological_process": "GO:0016042 lipid catabolic process;GO:0106342 omega-hydroxyceramide biosynthetic process;GO:0055088 lipid homeostasis;GO:0061436 establishment of skin barrier;GO:0030216 keratinocyte differentiation",
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        ],
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        "protein_name": "Muscleblind like splicing regulator 1",
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            {
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        ],
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        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003723 RNA binding;GO:0003725 double-stranded RNA binding",
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        ],
        "mass": 60493.0,
        "length": 540,
        "protein_name": "Netrin-G1",
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        "refseq_ac": [
            {
                "id": "XP_005204255",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005204255",
                "type": "external"
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        ],
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        "protein_names_uniprotkb": "Netrin-G1; Laminet-1",
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        "function": "Involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular and synaptic levels. Promotes neurite outgrowth of both axons and dendrites., [UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0098632 cell-cell adhesion mediator activity",
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        "go_biological_process": "GO:0007409 axonogenesis;GO:0009887 animal organ morphogenesis;GO:0050804 modulation of chemical synaptic transmission;GO:0010975 regulation of neuron projection development;GO:0009888 tissue development",
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        ],
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        "protein_name": "Sacsin",
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            {
                "id": "XP_015329322",
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        ],
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        "function": "Co-chaperone which acts as a regulator of the Hsp70 chaperone machinery and may be involved in the processing of other ataxia-linked proteins., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0042802 identical protein binding;GO:0050750 low-density lipoprotein particle receptor binding;GO:0070628 proteasome binding;GO:0030544 Hsp70 protein binding",
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        ],
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        "protein_name": "Nebulin-related-anchoring protein",
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        "function": "May be involved in anchoring the terminal actin filaments in the myofibril to the membrane and in transmitting tension from the myofibrils to the extracellular matrix., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0046872 metal ion binding;GO:0051015 actin filament binding;GO:0051371 muscle alpha-actinin binding;GO:0017166 vinculin binding",
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        ],
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        "protein_name": "Protein kinase C-binding protein NELL1",
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            {
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        "protein_names_uniprotkb": "Protein kinase C-binding protein NELL1; NEL-like protein 1",
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        "function": "Plays a role in the control of cell growth and differentiation. Promotes osteoblast cell differentiation and terminal mineralization., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "ec_number_list": [],
        "go_molecular_function": "GO:0003677 DNA binding;GO:0003688 DNA replication origin binding",
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        "kg_view_protein": true
    },
    {
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            {
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            }
        ],
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        "protein_name": "Uronyl 2-sulfotransferase",
        "gene_name": "UST",
        "organism": "Bovine",
        "refseq_name": "uronyl 2-sulfotransferase isoform 2",
        "refseq_ac": [
            {
                "id": "NP_001193756",
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                "type": "external"
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        ],
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        "protein_names_refseq": "uronyl 2-sulfotransferase isoform 2",
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        "pathway": " (R-BTA-2022870);  (R-BTA-2022923)",
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        "function": "Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to the 2-OH position of uronyl residues in glycosaminoglycan chains. Has mainly activity toward iduronyl residues in dermatan sulfate, and toward glucuronyl residues of chondroitin sulfate. Has little to no activity toward desulfated N-resulfated heparin or N-sulfoheparosan., [UniProtKB, UniProtKB]",
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        ],
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            {
                "id": "NP_001358947",
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        ],
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            {
                "id": "XP_024849553",
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        "protein_names_uniprotkb": "NK1 transcription factor-related protein 1; Homeobox protein SAX-2; NKX-1.1",
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        "function": "May be required for the coordinated crosstalk of factors involved in the maintenance of energy homeostasis, possibly by regulating the transcription of specific factors involved in energy balance., [UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific",
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        ],
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        "protein_name": "Phosphatidylcholine:ceramide cholinephosphotransferase 1",
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            {
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            {
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            },
            {
                "id": "3.1.4.62",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.62",
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            }
        ],
        "go_molecular_function": "GO:0002950 ceramide phosphoethanolamine synthase activity;GO:0033188 sphingomyelin synthase activity;GO:0016301 kinase activity;GO:0047493 ceramide cholinephosphotransferase activity",
        "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane",
        "go_biological_process": "GO:0006686 sphingomyelin biosynthetic process;GO:0006915 apoptotic process;GO:0046513 ceramide biosynthetic process",
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        ],
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        "length": 852,
        "protein_name": "Paladin",
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        "organism": "Bovine",
        "refseq_name": "paladin isoform X1",
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            {
                "id": "XP_024842442",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024842442",
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        ],
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        "go_molecular_function": "GO:0004725 protein tyrosine phosphatase activity",
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    },
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        ],
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        "protein_name": "CD109 antigen",
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            {
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        ],
        "gene_names_uniprotkb": "CD109",
        "gene_names_refseq": "CD109",
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        "protein_names_refseq": "CD109 antigen",
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        "function": "Modulates negatively TGFB1 signaling in keratinocytes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity",
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    {
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        ],
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        "protein_name": "Phospholipid-transporting ATPase",
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    },
    {
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            {
                "id": "A0A3Q1M6P0_BOVIN",
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                "type": "external"
            }
        ],
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        "protein_name": "plus-end-directed kinesin ATPase",
        "gene_name": "KIF1A",
        "organism": "Bovine",
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        "refseq_ac": [],
        "gene_names_uniprotkb": "KIF1A",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "plus-end-directed kinesin ATPase; 5.6.1.3",
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        "biomarker_type": "",
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        "ec_number_list": [],
        "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0042802 identical protein binding;GO:0008574 plus-end-directed microtubule motor activity",
        "go_cellular_component": "GO:0005874 microtubule;GO:0045202 synapse;GO:0030658 transport vesicle membrane",
        "go_biological_process": "GO:0010970 transport along microtubule",
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        "kg_view_protein": true
    },
    {
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            {
                "id": "A0A3Q1M6R3_BOVIN",
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                "type": "external"
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        ],
        "mass": 149576.0,
        "length": 1332,
        "protein_name": "Elongator complex protein 1",
        "gene_name": "ELP1",
        "organism": "Bovine",
        "refseq_name": "elongator complex protein 1",
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            {
                "id": "XP_003586478",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586478",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ELP1",
        "gene_names_refseq": "ELP1",
        "protein_names_uniprotkb": "Elongator complex protein 1",
        "protein_names_refseq": "elongator complex protein 1",
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        "function": "Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "predicted_n_glycosites": 0,
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        "ec_number_list": [],
        "go_molecular_function": "GO:0000049 tRNA binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0033588 elongator holoenzyme complex;GO:0005829 cytosol;GO:0005654 nucleoplasm",
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        "uniprot_canonical_ac": "A0A3Q1M6S7-1",
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            {
                "id": "A0A3Q1M6S7_BOVIN",
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        ],
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        "protein_name": "Olfactory receptor",
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        "refseq_name": "olfactory receptor family 14 subfamily J member 1",
        "refseq_ac": [
            {
                "id": "NP_001376790",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376790",
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            }
        ],
        "gene_names_uniprotkb": "OR14J1",
        "gene_names_refseq": "OR14J1",
        "protein_names_uniprotkb": "Olfactory receptor",
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        "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]; Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding",
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    {
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        ],
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        "function": "Metallothioneins have a high content of cysteine residues that bind various heavy metals., [UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0046872 metal ion binding",
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        "go_biological_process": "GO:0071276 cellular response to cadmium ion;GO:0071280 cellular response to copper ion;GO:0010273 detoxification of copper ion;GO:0006882 intracellular zinc ion homeostasis;GO:0071294 cellular response to zinc ion",
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        "protein_name": "glycogenin glucosyltransferase",
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        "refseq_ac": [],
        "gene_names_uniprotkb": "GYG1",
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        "function": "Glycogenin participates in the glycogen biosynthetic process along with glycogen synthase and glycogen branching enzyme. It catalyzes the formation of a short alpha (1,4)-glucosyl chain covalently attached via a glucose 1-O-tyrosyl linkage to internal tyrosine residues and these chains act as primers for the elongation reaction catalyzed by glycogen synthase., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "protein_name": "non-specific serine/threonine protein kinase",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150",
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            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12",
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        "pathway": " (R-BTA-159227);  (R-BTA-159230);  (R-BTA-159231);  (R-BTA-159236);  (R-BTA-1855170);  (R-BTA-1855196);  (R-BTA-1855229);  (R-BTA-191859);  (R-BTA-3108214);  (R-BTA-3232142);  (R-BTA-3301854);  (R-BTA-3371453);  (R-BTA-4085377);  (R-BTA-4551638);  (R-BTA-4570464);  (R-BTA-4615885);  (R-BTA-9615933)",
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        ],
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        ],
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        "function": "Enhances the ATPase activity of DHX15 by acting like a brace that tethers mobile sections of DHX15 together, stabilizing a functional conformation with high RNA affinity of DHX15. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription. May also act as a DNA-binding transcription regulator: interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes., [UniProtKB, UniProtKB, UniProtKB]",
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        ],
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        "protein_names_uniprotkb": "Non-selective voltage-gated ion channel VDAC2",
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        "function": "Catalyzes the scrambling of phospholipids across the outer mitochondrial membrane; the mechanism is unrelated to channel activity and is capable of translocating both anionic and zwitterionic phospholipids., [UniProtKB, UniProtKB]",
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        "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase; 3.4.19.12",
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        "function": "Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes., [UniProtKB, UniProtKB]",
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            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12",
                "type": "external"
            },
            {
                "id": "3.6.4.13",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13",
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            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.26.1",
                "type": "external"
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            {
                "id": "3.1.3.48",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48",
                "type": "external"
            }
        ],
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    },
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        ],
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            {
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        ],
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        ],
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        ],
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        "protein_name": "Acetoacetyl-CoA synthetase",
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            {
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        ],
        "go_molecular_function": "GO:0005524 ATP binding;GO:0030729 acetoacetate-CoA ligase activity",
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        ],
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        "protein_name": "Tripartite motif-containing protein 64-like",
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        "gene_names_uniprotkb": "LOC786377",
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        ],
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        ],
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            {
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        ],
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        "go_biological_process": "GO:0006955 immune response;GO:0045087 innate immune response;GO:0001916 positive regulation of T cell mediated cytotoxicity;GO:0048007 antigen processing and presentation, exogenous lipid antigen via MHC class Ib;GO:0048006 antigen processing and presentation, endogenous lipid antigen via MHC class Ib",
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    {
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            {
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        ],
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        "function": "Protein-histidine N-methyltransferase that specifically mediates 3-methylhistidine (tele-methylhistidine) methylation of actin at 'His-73'. Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery. Does not have protein-lysine N-methyltransferase activity and probably only catalyzes histidine methylation of actin., [UniProtKB, UniProtKB, UniProtKB]",
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        ],
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        "function": "Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient., [UniProtKB, UniProtKB, UniProtKB]",
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        "protein_name": "E3 ubiquitin-protein ligase RNF144A",
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            {
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        "function": "E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates the ubiquitination and degradation of the DNA damage kinase PRKDC during DNA damage. Positively regulates DNA virus or exogenous cytosolic DNA-triggered innate immune response by mediating STING1 ubiquitination and increasing its 'Lys-6'-linked ubiquitination and translocation from the endoplasmic reticulum to the Golgi leading to downstream signaling pathways. Plays a positive role in EGF-dependent cell proliferation by prolonging EGF/EGFR signaling during EGF stimulation through EGFR ubiquitination. Increases ERK activity independently of EGFR signaling by promoting polyubiquitination and subsequent degradation of VRK3 in the cytosol., [UniProtKB, UniProtKB, UniProtKB]",
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            }
        ],
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            {
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        "go_biological_process": "GO:0006878 intracellular copper ion homeostasis;GO:0055085 transmembrane transport;GO:0010273 detoxification of copper ion;GO:0060003 copper ion export;GO:0048023 positive regulation of melanin biosynthetic process",
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        ],
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        "protein_name": "Ataxin-7-like protein 3",
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        "protein_names_uniprotkb": "Ataxin-7-like protein 3; SAGA-associated factor 11 homolog",
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        "function": "Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex. Regulates H2B monoubiquitination (H2Bub1) levels. Affects subcellular distribution of ENY2, USP22 and ATXN7L3B., [UniProtKB, HAMAP, UniProtKB]",
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        ],
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        "organism": "Bovine",
        "refseq_name": "POU domain, class 6, transcription factor 1 isoform X1",
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            {
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        "go_cellular_component": "GO:0005634 nucleus",
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        "kg_view_protein": true
    },
    {
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            {
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        ],
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        "length": 560,
        "protein_name": "Zinc finger protein 579",
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            {
                "id": "XP_002695427",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002695427",
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            }
        ],
        "gene_names_uniprotkb": "ZNF579",
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        "protein_names_refseq": "zinc finger protein 579",
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        "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB]",
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        ],
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        "protein_names_uniprotkb": "Choline transporter-like protein",
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        ],
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        "go_cellular_component": "GO:0005634 nucleus;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane;GO:0017053 transcription repressor complex;GO:0000785 chromatin",
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        ],
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        "protein_name": "Lipase",
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                "type": "external"
            },
            {
                "id": "3.1.1.3",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3",
                "type": "external"
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            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4",
                "type": "external"
            },
            {
                "id": "3.1.1.5",
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            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.23",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.79",
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            },
            {
                "id": "2.3.1.51",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.26",
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            },
            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.116",
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            },
            {
                "id": "3.1.1.34",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.34",
                "type": "external"
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            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.13",
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            {
                "id": "3.1.1.6",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.6",
                "type": "external"
            }
        ],
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            {
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        ],
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        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "OR8B69",
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        "protein_names_uniprotkb": "Olfactory receptor",
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        "pathway_count": 0,
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        "function": "Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]",
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    {
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        ],
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        ],
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        "length": 309,
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            {
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        "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]; Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]",
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        "protein_name": "Cadherin 9",
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        "function": "Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types., [UniProtKB, UniProtKB]",
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        "protein_name": "ATP synthase subunit b",
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        "function": "Subunit b, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. Part of the complex F(0) domain. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "ec_number_list": [
            {
                "id": "2.3.1.-",
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            },
            {
                "id": "2.3.1.13",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.13",
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            {
                "id": "2.3.1.71",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.71",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0047962 glycine N-benzoyltransferase activity;GO:0047961 glycine N-acyltransferase activity",
        "go_cellular_component": "GO:0005739 mitochondrion",
        "go_biological_process": "GO:0009636 response to toxic substance;GO:0006544 glycine metabolic process",
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    },
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            }
        ],
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        "protein_name": "Peptidoglycan recognition protein 1",
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        "protein_names_uniprotkb": "Peptidoglycan recognition protein 1",
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        "function": "Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Also binds to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity., [UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0042834 peptidoglycan binding;GO:0008745 N-acetylmuramoyl-L-alanine amidase activity;GO:0008270 zinc ion binding;GO:0046982 protein heterodimerization activity;GO:0016019 peptidoglycan immune receptor activity",
        "go_cellular_component": "GO:0005615 extracellular space;GO:0032991 protein-containing complex",
        "go_biological_process": "GO:0006955 immune response;GO:0045087 innate immune response;GO:0050830 defense response to Gram-positive bacterium;GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0016045 detection of bacterium",
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    },
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        ],
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        "length": 313,
        "protein_name": "Olfactory receptor",
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            {
                "id": "NP_001377087",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377087",
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        ],
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        "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]; Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]",
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        ],
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        "function": "Glycogen-branching enzyme participates in the glycogen biosynthetic process along with glycogenin and glycogen synthase. Generates alpha-1,6-glucosidic branches from alpha-1,4-linked glucose chains, to increase solubility of the glycogen polymer., [UniProtKB, UniProtKB]",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.11",
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        ],
        "go_molecular_function": "GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0003844 1,4-alpha-glucan branching enzyme activity;GO:0043169 cation binding",
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    },
    {
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            }
        ],
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        "length": 244,
        "protein_name": "Sperm-tail PG-rich repeat containing 4",
        "gene_name": "STPG4",
        "organism": "Bovine",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "STPG4",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Sperm-tail PG-rich repeat containing 4",
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        "go_molecular_function": "GO:0003682 chromatin binding;GO:0042393 histone binding",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0001939 female pronucleus;GO:0001940 male pronucleus;GO:0042585 germinal vesicle;GO:0005634 nucleus",
        "go_biological_process": "GO:0044727 epigenetic programing of male pronucleus",
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        ],
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        "protein_name": "U6 snRNA-associated Sm-like protein LSm6",
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            {
                "id": "XP_059734084",
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        ],
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        "gene_names_refseq": "LOC107132243",
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        "protein_names_refseq": "U6 snRNA-associated Sm-like protein LSm6",
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        "go_molecular_function": "GO:0003723 RNA binding",
        "go_cellular_component": "GO:0005730 nucleolus;GO:0005681 spliceosomal complex;GO:0000932 P-body;GO:0120115 Lsm2-8 complex;GO:0046540 U4/U6 x U5 tri-snRNP complex",
        "go_biological_process": "GO:0008033 tRNA processing;GO:0000398 mRNA splicing, via spliceosome;GO:0030490 maturation of SSU-rRNA",
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            {
                "id": "A0A3Q1MPS6_BOVIN",
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        ],
        "mass": 50012.0,
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        "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein",
        "gene_name": "OR6Z9",
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        "refseq_ac": [],
        "gene_names_uniprotkb": "OR6Z9",
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        "protein_names_uniprotkb": "G-protein coupled receptors family 1 profile domain-containing protein",
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        "function": "Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]",
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            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.35",
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            },
            {
                "id": "3.1.4.17",
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            },
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            {
                "id": "3.6.1.25",
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            }
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    },
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            }
        ],
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        "function": "Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        ],
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            {
                "id": "XP_005210647",
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        "pathway": " (R-BTA-2565942);  (R-BTA-380259);  (R-BTA-380270);  (R-BTA-380284);  (R-BTA-380320);  (R-BTA-5620912);  (R-BTA-8854518)",
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            {
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        "function": "Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL (RELA/p65 and NFKB1/p50) dimers in the cytoplasm by masking their nuclear localization signals. On cellular stimulation by immune and pro-inflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription., [UniProtKB, UniProtKB]",
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        ],
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        "protein_name": "Gamma-aminobutyric acid type A receptor subunit beta2",
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                "id": "XP_024850304",
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            }
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        "go_cellular_component": "GO:0098982 GABA-ergic synapse;GO:0043197 dendritic spine;GO:0031410 cytoplasmic vesicle;GO:0034707 chloride channel complex;GO:1902711 GABA-A receptor complex",
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        "protein_name": "Carbohydrate sulfotransferase",
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        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding",
        "go_cellular_component": "GO:0098826 endoplasmic reticulum tubular network membrane",
        "go_biological_process": "GO:1903373 positive regulation of endoplasmic reticulum tubular network organization;GO:0071788 endoplasmic reticulum tubular network maintenance",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
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        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.010000000000000000.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A3Q1MWI9-1",
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            {
                "id": "A0A3Q1MWI9_BOVIN",
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                "type": "external"
            }
        ],
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        "length": 877,
        "protein_name": "Protein O-mannosyl-transferase TMTC1",
        "gene_name": "TMTC1",
        "organism": "Bovine",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "TMTC1",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Protein O-mannosyl-transferase TMTC1; 2.4.1.109; Transmembrane O-mannosyltransferase targeting cadherins 1; Transmembrane and tetratricopeptide repeat-containing 1",
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        "pathway": " (bta:533191)",
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        "function": "Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O-mannosyl-transferase on other proteins such as PDIA3., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity;GO:0000030 mannosyltransferase activity",
        "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane",
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        ],
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        "protein_name": "Voltage-dependent N-type calcium channel subunit alpha",
        "gene_name": "CACNA1B",
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        "function": "Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This alpha-1B subunit gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group. They are involved in pain signaling. Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons. Mediates Ca(2+) release probability at hippocampal neuronal soma and synaptic terminals., [UniProtKB, UniProtKB, UniProtKB]",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1",
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        ],
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        ],
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                "id": "NP_001179089",
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        "protein_name": "Rho GTPase-activating protein 42",
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        "function": "May influence blood pressure by functioning as a GTPase-activating protein for RHOA in vascular smooth muscle., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        ],
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        "go_molecular_function": "GO:0008234 cysteine-type peptidase activity;GO:0016929 deSUMOylase activity",
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        ],
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        "protein_name": "Ribosome quality control complex subunit NEMF",
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        ],
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        "protein_names_uniprotkb": "Ribosome quality control complex subunit NEMF; Nuclear export mediator factor",
        "protein_names_refseq": "ribosome quality control complex subunit NEMF isoform X1",
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        "go_molecular_function": "GO:0043023 ribosomal large subunit binding;GO:1904678 alpha-aminoacyl-tRNA binding",
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        "gene_names_uniprotkb": "LOC112445816",
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            },
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            },
            {
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        "go_cellular_component": "GO:0097229 sperm end piece;GO:0097228 sperm principal piece;GO:0097225 sperm midpiece;GO:0120212 sperm head-tail coupling apparatus",
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        "protein_name": "HUWE1 associated protein modifying stress responses",
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        "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding",
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        "protein_name": "Adenylate cyclase type 10",
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            {
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        "protein_names_uniprotkb": "Adenylate cyclase type 10; 4.6.1.1; Germ cell soluble adenylyl cyclase; Testicular soluble adenylyl cyclase",
        "protein_names_refseq": "adenylate cyclase type 10 isoform X1",
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        "function": "Catalyzes the formation of the signaling molecule cAMP. May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels. Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. Involved in ciliary beat regulation., [UniProtKB, UniProtKB]",
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        "ec_number_list": [
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                "url": "https://www.rhea-db.org/rhea/?query=ec:4.6.1.1",
                "type": "external"
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            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.85",
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        "go_cellular_component": "GO:0005576 extracellular region;GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005886 plasma membrane;GO:0031514 motile cilium",
        "go_biological_process": "GO:0003351 epithelial cilium movement involved in extracellular fluid movement;GO:0006171 cAMP biosynthetic process;GO:0035556 intracellular signal transduction;GO:0009190 cyclic nucleotide biosynthetic process",
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        ],
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        "length": 316,
        "protein_name": "Olfactory receptor family 10 subfamily H member 4T",
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        "protein_names_uniprotkb": "Olfactory receptor family 10 subfamily H member 4T",
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        "protein_name": "OTU domain-containing protein 3",
        "gene_name": "OTUD3",
        "organism": "Bovine",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "OTUD3",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "OTU domain-containing protein 3; 3.4.19.12",
        "protein_names_refseq": "",
        "tax_id": 9913,
        "disease": "",
        "pathway": " (bta:514809);  (R-BTA-5689896);  (R-BTA-8948751)",
        "pathway_count": 3,
        "publication_count": 0,
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        "function": "Deubiquitinating enzyme that hydrolyzes 'Lys-6'- and 'Lys-11'-linked polyubiquitin. Also hydrolyzes heterotypic (mixed and branched) and homotypic chains. Important regulator of energy metabolism. Glucose and fatty acids trigger its nuclear translocation by CBP-dependent acetylation. In the nucleus, deubiquitinates and stabilizes the nuclear receptor PPARD regulating the expression of various genes involved in glucose and lipid metabolism and oxidative phosphorylation. Also acts as a negative regulator of the ribosome quality control (RQC) by mediating deubiquitination of 40S ribosomal proteins RPS10/eS10 and RPS20/uS10, thereby antagonizing ZNF598-mediated 40S ubiquitination., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "ec_number_list": [
            {
                "id": "3.4.19.12",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12",
                "type": "external"
            },
            {
                "id": "3.1.3.67",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67",
                "type": "external"
            },
            {
                "id": "3.1.3.16",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16",
                "type": "external"
            },
            {
                "id": "3.1.3.48",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48",
                "type": "external"
            }
        ],
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        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0006508 proteolysis;GO:0050821 protein stabilization;GO:0031669 cellular response to nutrient levels;GO:0044313 protein K6-linked deubiquitination;GO:0035871 protein K11-linked deubiquitination",
        "synthesized_glycan_count": 0,
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    },
    {
        "uniprot_canonical_ac": "A0AAF6YTK9-1",
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            {
                "id": "A0AAF6YTK9_BOVIN",
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            }
        ],
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        "length": 522,
        "protein_name": "Ubiquitin carboxyl-terminal hydrolase",
        "gene_name": "USP22",
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        "refseq_ac": [],
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        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase; 3.4.19.12",
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        "function": "Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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    },
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            {
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                "type": "external"
            }
        ],
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        "length": 288,
        "protein_name": "Coatomer subunit zeta",
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        "refseq_ac": [
            {
                "id": "XP_005206148",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005206148",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "COPZ1",
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        "function": "The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:0000139 Golgi membrane;GO:0030126 COPI vesicle coat",
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            {
                "id": "A0AAF6DLZ6_BOVIN",
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        ],
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        "protein_name": "BBSome complex member BBS5",
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        "gene_names_uniprotkb": "BBS5",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "BBSome complex member BBS5; Kelch repeat and BTB domain-containing protein 10; Kelch-like protein 41",
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        "function": "Involved in skeletal muscle development and differentiation. Regulates proliferation and differentiation of myoblasts and plays a role in myofibril assembly by promoting lateral fusion of adjacent thin fibrils into mature, wide myofibrils. Required for pseudopod elongation in transformed cells., [UniProtKB, UniProtKB]; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for BBSome complex ciliary localization but not for the proper complex assembly., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:0034451 centriolar satellite;GO:0060170 ciliary membrane;GO:0034464 BBSome;GO:0005829 cytosol;GO:0031143 pseudopodium",
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    },
    {
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            {
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        ],
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        "protein_name": "tRNA N(3)-cytidine methyltransferase",
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        "organism": "Bovine",
        "refseq_name": "tRNA N(3)-cytidine methyltransferase METTL2 isoform X1",
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            {
                "id": "XP_010814629",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010814629",
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            }
        ],
        "gene_names_uniprotkb": "METTL2A",
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        "function": "S-adenosyl-L-methionine-dependent methyltransferase., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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            }
        ],
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        ],
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        "protein_name": "C-X-C chemokine receptor type 4",
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        "organism": "Bovine",
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        "gene_names_uniprotkb": "CXCR4",
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        "protein_names_uniprotkb": "C-X-C chemokine receptor type 4",
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        "go_molecular_function": "GO:0004950 chemokine receptor activity;GO:0003779 actin binding;GO:0019957 C-C chemokine binding;GO:0031625 ubiquitin protein ligase binding;GO:0043130 ubiquitin binding",
        "go_cellular_component": "GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0005764 lysosome;GO:0005770 late endosome;GO:0070161 anchoring junction",
        "go_biological_process": "GO:0006935 chemotaxis;GO:0016477 cell migration;GO:0030334 regulation of cell migration;GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0030155 regulation of cell adhesion",
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        ],
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        "protein_name": "Prothymosin alpha",
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        "refseq_name": "prothymosin alpha isoform X1",
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            {
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        ],
        "gene_names_uniprotkb": "PTMA",
        "gene_names_refseq": "PTMA",
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        "function": "Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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            {
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        ],
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        ],
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        "function": "Mediates responses to nitric oxide (NO) by catalyzing the biosynthesis of the signaling molecule cGMP., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        ],
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        "function": "GRF is released by the hypothalamus and acts on the adenohypophyse to stimulate the secretion of growth hormone., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "protein_name": "Pre-mRNA-splicing factor SYF1",
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        "function": "Involved in pre-mRNA splicing as component of the spliceosome. Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing., [UniProtKB, UniProtKB]",
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]
