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    {
        "uniprot_canonical_ac": "A0A8M3B8F0-1",
        "uniprot_id": [
            {
                "id": "A0A8M3B8F0_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M3B8F0",
                "type": "external"
            }
        ],
        "mass": 109980.0,
        "length": 972,
        "protein_name": "Storkhead-box protein 2 isoform X1",
        "gene_name": "stox2b",
        "organism": "Zebrafish",
        "refseq_name": "storkhead-box protein 2 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009306020",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009306020",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "stox2b",
        "gene_names_refseq": "stox2b",
        "protein_names_uniprotkb": "Storkhead-box protein 2 isoform X1",
        "protein_names_refseq": "storkhead-box protein 2 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100003272)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 3,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 3,
        "predicted_c_glycosites": 0,
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        "mined_glycosites": 0,
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        "reported_o_glycosites": 0,
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        "total_reported_n_glycosites": 0,
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        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 3,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A8M3B8F0-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.010000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M3B5V9-1",
        "uniprot_id": [
            {
                "id": "A0A8M3B5V9_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M3B5V9",
                "type": "external"
            }
        ],
        "mass": 75654.0,
        "length": 654,
        "protein_name": "HECT domain-containing protein",
        "gene_name": "LOC101883005",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "XP_009292866",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009292866",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC101883005; LOC101884789; LOC103909877",
        "gene_names_refseq": "LOC101883005",
        "protein_names_uniprotkb": "HECT domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:101883005);  (dre:101884789);  (dre:103909877)",
        "pathway_count": 3,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "reported_n_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
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        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0004842 ubiquitin-protein transferase activity",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A8M3B5V9-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M3B5W8-1",
        "uniprot_id": [
            {
                "id": "A0A8M3B5W8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M3B5W8",
                "type": "external"
            }
        ],
        "mass": 29750.0,
        "length": 253,
        "protein_name": "Transcription factor Spi-C",
        "gene_name": "LOC101885606",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "XP_009294897",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009294897",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC101885606",
        "gene_names_refseq": "LOC101885606",
        "protein_names_uniprotkb": "Transcription factor Spi-C",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:101885606)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
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        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
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        "reported_o_glycosites_with_glycan": 0,
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        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A8M3B5W8-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A8M3B5X1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M3B5X1",
                "type": "external"
            }
        ],
        "mass": 38674.0,
        "length": 346,
        "protein_name": "Acetylserotonin O-methyltransferase",
        "gene_name": "asmt",
        "organism": "Zebrafish",
        "refseq_name": "acetylserotonin O-methyltransferase isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009303292",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009303292",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "asmt; hiomt; zgc:171885",
        "gene_names_refseq": "asmt; hiomt; zgc:171885",
        "protein_names_uniprotkb": "Acetylserotonin O-methyltransferase; 2.1.1.4; Hydroxyindole O-methyltransferase",
        "protein_names_refseq": "acetylserotonin O-methyltransferase isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine)., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "reported_o_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0017096 acetylserotonin O-methyltransferase activity",
        "go_cellular_component": "",
        "go_biological_process": "GO:0036269 swimming behavior;GO:0032259 methylation;GO:0030187 melatonin biosynthetic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A8M3B5X1-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M3B5Y9-1",
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            {
                "id": "A0A8M3B5Y9_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M3B5Y9",
                "type": "external"
            }
        ],
        "mass": 68293.0,
        "length": 616,
        "protein_name": "Centrosomal protein of 97 kDa",
        "gene_name": "cep97",
        "organism": "Zebrafish",
        "refseq_name": "centrosomal protein of 97 kDa isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009303333",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009303333",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cep97; lrriq2; zgc:63856",
        "gene_names_refseq": "cep97; lrriq2; zgc:63856",
        "protein_names_uniprotkb": "Centrosomal protein of 97 kDa; Leucine-rich repeat and IQ domain-containing protein 2",
        "protein_names_refseq": "centrosomal protein of 97 kDa isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:386640)",
        "pathway_count": 1,
        "publication_count": 3,
        "publication_id_list": "17719728;26566657;27189481",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_009303333.2. COMPLETENESS: full length., [RefSeq]; Acts as a key negative regulator of ciliogenesis in collaboration with CCP110 by capping the mother centriole thereby preventing cilia formation. Required for recruitment of CCP110 to the centrosome., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "predicted_o_glycosites": 0,
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        "reported_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005813 centrosome",
        "go_biological_process": "GO:0030030 cell projection organization",
        "synthesized_glycan_count": 0,
        "hit_score": 0.4,
        "record_id": "A0A8M3B5Y9-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A8M3B5Z6_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M3B5Z6",
                "type": "external"
            }
        ],
        "mass": 145094.0,
        "length": 1274,
        "protein_name": "Ras-specific guanine nucleotide-releasing factor 2-like isoform X1",
        "gene_name": "rasgrf2a",
        "organism": "Zebrafish",
        "refseq_name": "ras-specific guanine nucleotide-releasing factor 2-like isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009303357",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009303357",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "rasgrf2a",
        "gene_names_refseq": "rasgrf2a",
        "protein_names_uniprotkb": "Ras-specific guanine nucleotide-releasing factor 2-like isoform X1",
        "protein_names_refseq": "ras-specific guanine nucleotide-releasing factor 2-like isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:558859)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "missing_score": 10000,
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        "glycan_count": 0,
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0007265 Ras protein signal transduction;GO:0007264 small GTPase-mediated signal transduction",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
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        "record_type": "protein",
        "filter_code": "0000000.0000001.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A8M3B618_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M3B618",
                "type": "external"
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        ],
        "mass": 86419.0,
        "length": 789,
        "protein_name": "Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A",
        "gene_name": "inpp5ja",
        "organism": "Zebrafish",
        "refseq_name": "inositol polyphosphate 5-phosphatase K",
        "refseq_ac": [
            {
                "id": "XP_009303405",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009303405",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "inpp5ja",
        "gene_names_refseq": "inpp5ja",
        "protein_names_uniprotkb": "Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A; 3.1.3.36; 3.1.3.56; Inositol polyphosphate 5-phosphatase J; Phosphatidylinositol 1,3,4,5-tetrakisphosphate 5-phosphatase; Phosphatidylinositol 1,4,5-trisphosphate 5-phosphatase",
        "protein_names_refseq": "inositol polyphosphate 5-phosphatase K",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:569568)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 24, 2016 this sequence version replaced XP_009303405.1. COMPLETENESS: full length., [RefSeq]; Inositol 5-phosphatase, which converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate. Also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles., [UniProtKB, UniProtKB]",
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        "ec_number_list": [
            {
                "id": "3.1.3.86",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.86",
                "type": "external"
            },
            {
                "id": "3.1.3.56",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.56",
                "type": "external"
            },
            {
                "id": "3.1.3.36",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.36",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0017124 SH3 domain binding;GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity;GO:0004445 inositol-polyphosphate 5-phosphatase activity",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0120025 plasma membrane bounded cell projection",
        "go_biological_process": "GO:0046856 phosphatidylinositol dephosphorylation",
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    {
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                "url": "https://www.uniprot.org/uniprot/A0A8M3B6S9",
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        "length": 747,
        "protein_name": "Phospholipid phosphatase-related protein type 3",
        "gene_name": "plppr4b",
        "organism": "Zebrafish",
        "refseq_name": "phospholipid phosphatase-related protein type 4 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009295825",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009295825",
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        "gene_names_uniprotkb": "plppr4b",
        "gene_names_refseq": "plppr4b",
        "protein_names_uniprotkb": "Phospholipid phosphatase-related protein type 3; Inactive phospholipid phosphatase PLPPR3; Lipid phosphate phosphatase-related protein type 3; Plasticity-related gene 2 protein",
        "protein_names_refseq": "phospholipid phosphatase-related protein type 4 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009295825.1. COMPLETENESS: full length., [RefSeq]",
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        "length": 266,
        "protein_name": "Endonuclease domain-containing 1 protein-like",
        "gene_name": "LOC103911895",
        "organism": "Zebrafish",
        "refseq_name": "endonuclease domain-containing 1 protein-like",
        "refseq_ac": [
            {
                "id": "XP_009304673",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009304673",
                "type": "external"
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        "gene_names_uniprotkb": "LOC103911895",
        "gene_names_refseq": "LOC103911895",
        "protein_names_uniprotkb": "Endonuclease domain-containing 1 protein-like",
        "protein_names_refseq": "endonuclease domain-containing 1 protein-like",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio                   :: 17% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0016787 hydrolase activity;GO:0046872 metal ion binding;GO:0003676 nucleic acid binding",
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        "kg_view_protein": true
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    {
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        "uniprot_id": [
            {
                "id": "A0A8M3B791_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M3B791",
                "type": "external"
            }
        ],
        "mass": 37619.0,
        "length": 341,
        "protein_name": "Chymotrypsin-like protease CTRL-1 isoform X1",
        "gene_name": "si:ch73-182e20.4",
        "organism": "Zebrafish",
        "refseq_name": "chymotrypsin-like protease CTRL-1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009296334",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009296334",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:ch73-182e20.4",
        "gene_names_refseq": "si:ch73-182e20.4",
        "protein_names_uniprotkb": "Chymotrypsin-like protease CTRL-1 isoform X1",
        "protein_names_refseq": "chymotrypsin-like protease CTRL-1 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100535157)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_009296334.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0008236 serine-type peptidase activity",
        "go_cellular_component": "",
        "go_biological_process": "GO:0016485 protein processing",
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        "protein_name": "C2H2-type domain-containing protein",
        "gene_name": "LOC101884850",
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        "refseq_name": "uncharacterized protein",
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            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009296516",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC101884850",
        "gene_names_refseq": "LOC101884850",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_cellular_component": "GO:0005654 nucleoplasm",
        "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0002682 regulation of immune system process;GO:0001817 regulation of cytokine production",
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        "protein_name": "Transcription factor Sox-14",
        "gene_name": "LOC103910042",
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        "gene_names_refseq": "LOC103910042",
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        "protein_names_refseq": "transcription factor Sox-14",
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            }
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        "gene_names_refseq": "setd1bb",
        "protein_names_uniprotkb": "Histone-lysine N-methyltransferase SETD1B-A",
        "protein_names_refseq": "histone-lysine N-methyltransferase SETD1B-A",
        "tax_id": 7955,
        "disease": "neurodevelopmental disorder with speech impairment and dysmorphic facies (Disease Ontology:DOID:0070417)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_molecular_function": "GO:0003723 RNA binding;GO:0042800 histone H3K4 methyltransferase activity",
        "go_cellular_component": "GO:0005694 chromosome;GO:0048188 Set1C/COMPASS complex",
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        "kg_view_protein": true
    },
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            {
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                "url": "https://www.uniprot.org/uniprot/A0A8M3BBZ7",
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        ],
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        "gene_name": "tbc1d10aa",
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        "refseq_name": "uncharacterized protein tbc1d10aa isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009302447",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009302447",
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        ],
        "gene_names_uniprotkb": "tbc1d10aa",
        "gene_names_refseq": "tbc1d10aa",
        "protein_names_uniprotkb": "Uncharacterized protein tbc1d10aa isoform X1",
        "protein_names_refseq": "uncharacterized protein tbc1d10aa isoform X1",
        "tax_id": 7955,
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        "pathway": " (dre:325772)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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            {
                "id": "A0A8M3BC47_DANRE",
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        ],
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        "gene_name": "frmd3",
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        "refseq_ac": [
            {
                "id": "XP_002663277",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002663277",
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        ],
        "gene_names_uniprotkb": "frmd3",
        "gene_names_refseq": "frmd3",
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        "protein_names_refseq": "FERM domain-containing protein 3 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_002663277.1. COMPLETENESS: full length., [RefSeq]",
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                "url": "https://www.uniprot.org/uniprot/A0A8M3BC64",
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        ],
        "mass": 121930.0,
        "length": 1080,
        "protein_name": "Voltage-dependent calcium channel subunit alpha-2/delta-3 isoform X1",
        "gene_name": "cacna2d3a",
        "organism": "Zebrafish",
        "refseq_name": "voltage-dependent calcium channel subunit alpha-2/delta-3 isoform X1",
        "refseq_ac": [
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009302617",
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        ],
        "gene_names_uniprotkb": "cacna2d3a",
        "gene_names_refseq": "cacna2d3a",
        "protein_names_uniprotkb": "Voltage-dependent calcium channel subunit alpha-2/delta-3 isoform X1",
        "protein_names_refseq": "voltage-dependent calcium channel subunit alpha-2/delta-3 isoform X1",
        "tax_id": 7955,
        "disease": "nicotine dependence (Disease Ontology:DOID:0050742); heart conduction disease (Disease Ontology:DOID:10273)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0046872 metal ion binding;GO:0005245 voltage-gated calcium channel activity;GO:0005262 calcium channel activity",
        "go_cellular_component": "GO:0005891 voltage-gated calcium channel complex;GO:0034702 monoatomic ion channel complex",
        "go_biological_process": "",
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        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A8M3BCA8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M3BCA8",
                "type": "external"
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        ],
        "mass": 26826.0,
        "length": 240,
        "protein_name": "dipeptidase E",
        "gene_name": "si:dkey-69o16.5",
        "organism": "Zebrafish",
        "refseq_name": "Alpha-aspartyl dipeptidase-like",
        "refseq_ac": [
            {
                "id": "NP_001137527",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137527",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "si:dkey-69o16.5",
        "gene_names_refseq": "si:dkey-69o16.5",
        "protein_names_uniprotkb": "dipeptidase E; 3.4.13.21; Asp-specific dipeptidase",
        "protein_names_refseq": "Alpha-aspartyl dipeptidase-like",
        "tax_id": 7955,
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        "pathway": " (dre:100149419)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01000502.1, EH479640.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000009.1. On Jan 23, 2009 this sequence version replaced XP_001923778.1., [RefSeq]; Hydrolyzes dipeptides containing N-terminal aspartate residues., [UniProtKB, UniProtKB]",
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        "secondary_ac_list": "B8JLK9",
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        "go_cellular_component": "GO:0005737 cytoplasm",
        "go_biological_process": "GO:0006508 proteolysis",
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    {
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        ],
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        "protein_name": "Neuromedin-S isoform X1",
        "gene_name": "nms",
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        "refseq_name": "neuromedin-S isoform X1",
        "refseq_ac": [
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009303090",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "nms",
        "gene_names_refseq": "nms",
        "protein_names_uniprotkb": "Neuromedin-S isoform X1",
        "protein_names_refseq": "neuromedin-S isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009303090.1. COMPLETENESS: full length., [RefSeq]",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "Death effector domain-containing 1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "refseq_ac": [
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        "protein_names_refseq": "uncharacterized protein LOC564531",
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        "protein_name": "Protein FAM13A-like",
        "gene_name": "LOC567650",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206660",
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        "gene_names_uniprotkb": "LOC567650",
        "gene_names_refseq": "LOC567650",
        "protein_names_uniprotkb": "Protein FAM13A-like",
        "protein_names_refseq": "protein FAM13A-like",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_017206660.2. COMPLETENESS: full length., [RefSeq]",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208791",
                "type": "external"
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        "gene_names_refseq": "si:dkey-78l4.10",
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        "protein_names_refseq": "granzyme B",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_017208791.1. COMPLETENESS: full length., [RefSeq]",
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        "missing_score": 10000,
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            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208838",
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        ],
        "gene_names_uniprotkb": "LOC100008030",
        "gene_names_refseq": "LOC100008030",
        "protein_names_uniprotkb": "C2H2-type domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
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        "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome",
        "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045893 positive regulation of DNA-templated transcription;GO:0045595 regulation of cell differentiation",
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        "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25-like isoform X1",
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        ],
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        "protein_name": "Uncharacterized protein si:ch73-299h12.1",
        "gene_name": "si:ch73-299h12.1",
        "organism": "Zebrafish",
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        "refseq_ac": [
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208438",
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        "protein_names_uniprotkb": "Pregnancy zone protein isoform X5",
        "protein_names_refseq": "pregnancy zone protein isoform X5",
        "tax_id": 7955,
        "disease": "otitis media (Disease Ontology:DOID:10754)",
        "pathway": " (dre:100137103)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017210396.1. COMPLETENESS: full length., [RefSeq]",
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        "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity",
        "go_cellular_component": "GO:0005615 extracellular space",
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        "kg_view_protein": true
    },
    {
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            {
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                "url": "https://www.uniprot.org/uniprot/A0A8M6YXV8",
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        ],
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        "protein_name": "Protein NLRC3-like isoform X1",
        "gene_name": "LOC100150280",
        "organism": "Zebrafish",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021330974",
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        ],
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        "protein_names_refseq": "protein NLRC3-like isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021330974.1. COMPLETENESS: full length., [RefSeq]",
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    },
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        ],
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                "id": "XP_017211320",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211320",
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        ],
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.47",
                "type": "external"
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        ],
        "go_molecular_function": "GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity",
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    {
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            {
                "id": "A0A8M6YY12_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M6YY12",
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        ],
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        "protein_name": "von Willebrand factor A domain-containing protein 5B1",
        "gene_name": "vwa5b1",
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        "refseq_name": "von Willebrand factor A domain-containing protein 5B1",
        "refseq_ac": [
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209274",
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        ],
        "gene_names_uniprotkb": "vwa5b1",
        "gene_names_refseq": "vwa5b1",
        "protein_names_uniprotkb": "von Willebrand factor A domain-containing protein 5B1",
        "protein_names_refseq": "von Willebrand factor A domain-containing protein 5B1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017209274.2. COMPLETENESS: full length., [RefSeq]",
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        "kg_view_protein": true
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    {
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                "url": "https://www.uniprot.org/uniprot/A0A8M6YY19",
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        ],
        "mass": 251415.0,
        "length": 2292,
        "protein_name": "Protein sidekick-1 isoform X1",
        "gene_name": "sdk1b",
        "organism": "Zebrafish",
        "refseq_name": "sidekick cell adhesion molecule 1b isoform 1",
        "refseq_ac": [
            {
                "id": "NP_001430356",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001430356",
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        "gene_names_uniprotkb": "sdk1b",
        "gene_names_refseq": "sdk1b; si:rp71-86k19.1; zgc:171522",
        "protein_names_uniprotkb": "Protein sidekick-1 isoform X1",
        "protein_names_refseq": "sidekick cell adhesion molecule 1b isoform 1",
        "tax_id": 7955,
        "disease": "obesity (Disease Ontology:DOID:9970)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01034663.1, SRR32588722.47691758.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1. On Sep 15, 2025 this sequence version replaced XP_017211454.2., [RefSeq]",
        "predicted_glycosites": 0,
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        ],
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        "protein_names_refseq": "uncharacterized protein isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017211461.1. COMPLETENESS: full length., [RefSeq]",
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        ],
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    },
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        ],
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                "id": "XP_017210734",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210734",
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        ],
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        "protein_names_refseq": "GLIPR1-like protein 1 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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    },
    {
        "uniprot_canonical_ac": "A0A8M6YY96-1",
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            {
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        ],
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        "gene_name": "si:dkey-105h11.2",
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        "gene_names_uniprotkb": "si:dkey-105h11.2",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_017209468.1. COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "Uncharacterized protein znf1046 isoform X1",
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        "protein_names_uniprotkb": "Uncharacterized protein znf1046 isoform X1",
        "protein_names_refseq": "uncharacterized protein znf1046 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_017210830.1. COMPLETENESS: full length., [RefSeq]",
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        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific",
        "go_cellular_component": "GO:0005634 nucleus",
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        ],
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        "protein_name": "Serine/arginine repetitive matrix protein 3 isoform X1",
        "gene_name": "srrm3",
        "organism": "Zebrafish",
        "refseq_name": "serine/arginine repetitive matrix protein 3 isoform X1",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211705",
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        "gene_names_uniprotkb": "srrm3",
        "gene_names_refseq": "srrm3",
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        "protein_names_refseq": "serine/arginine repetitive matrix protein 3 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_017211705.1. COMPLETENESS: full length., [RefSeq]; RNA splicing factor that regulates inclusion of microexons in mRNA transcripts (PubMed:35858306). Through the regulation of splicing in the brain, may be required for GABAergic neurotransmission and motor coordination (By similarity). In pancreatic islets, mediates microexon inclusion and regulates glucose- or amino acid-stimulated insulin secretion, as well as glucagon secretion (By similarity). Important for islet morphogenesis during pancreas development (By similarity). Regulates microexon inclusion in the developing retina, which is required for outer segment maintenance and vision (PubMed:35858306)., [UniProtKB, PubMed, UniProtKB]",
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        "go_molecular_function": "GO:0003729 mRNA binding",
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        ],
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        "length": 466,
        "protein_name": "Coiled-coil domain-containing protein 77 isoform X1",
        "gene_name": "ccdc77",
        "organism": "Zebrafish",
        "refseq_name": "coiled-coil domain-containing protein 77",
        "refseq_ac": [
            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020649",
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        "gene_names_uniprotkb": "ccdc77; zgc:114121",
        "gene_names_refseq": "ccdc77; zgc:114121",
        "protein_names_uniprotkb": "Coiled-coil domain-containing protein 77 isoform X1",
        "protein_names_refseq": "coiled-coil domain-containing protein 77",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395039.1967074.1, SRR26395015.1275150.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA898399, SAMEA898400 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000025.1. On or before Jul 31, 2025 this sequence version replaced XP_073798180.1, NP_001020649.1., [RefSeq]",
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        "protein_names_refseq": "C-type lectin domain family 17, member A-like",
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        "protein_name": "Integrase catalytic domain-containing protein",
        "gene_name": "LOC101885868",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "XP_021334657",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021334657",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC101885868",
        "gene_names_refseq": "LOC101885868",
        "protein_names_uniprotkb": "Integrase catalytic domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:101885868)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
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        "mined_s_glycosites": 0,
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        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003676 nucleic acid binding",
        "go_cellular_component": "",
        "go_biological_process": "GO:0015074 DNA integration",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A8M9PSZ0-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M9PT25-1",
        "uniprot_id": [
            {
                "id": "A0A8M9PT25_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9PT25",
                "type": "external"
            }
        ],
        "mass": 15149.0,
        "length": 129,
        "protein_name": "Transcription factor HES-4-B-like",
        "gene_name": "LOC108180270",
        "organism": "Zebrafish",
        "refseq_name": "transcription factor HES-4-B-like",
        "refseq_ac": [
            {
                "id": "NP_001429569",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429569",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC108180270",
        "gene_names_refseq": "LOC108180270",
        "protein_names_uniprotkb": "Transcription factor HES-4-B-like",
        "protein_names_refseq": "transcription factor HES-4-B-like",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:108180270)",
        "pathway_count": 1,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588720.354817.1, SRR32588723.444648.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA898401, SAMN06645146 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1. On Aug 18, 2025 this sequence version replaced XP_021324225.2., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "reported_mutagensis": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 0,
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0007219 Notch signaling pathway;GO:0045665 negative regulation of neuron differentiation;GO:0009952 anterior/posterior pattern specification",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A8M9PT25-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M9PWN4-1",
        "uniprot_id": [
            {
                "id": "A0A8M9PWN4_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9PWN4",
                "type": "external"
            }
        ],
        "mass": 168130.0,
        "length": 1516,
        "protein_name": "Pleckstrin homology domain-containing family G member 1 isoform X1",
        "gene_name": "LOC101886810",
        "organism": "Zebrafish",
        "refseq_name": "pleckstrin homology domain-containing family G member 1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_021325545",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325545",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC101886810",
        "gene_names_refseq": "LOC101886810",
        "protein_names_uniprotkb": "Pleckstrin homology domain-containing family G member 1 isoform X1",
        "protein_names_refseq": "pleckstrin homology domain-containing family G member 1 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:101886810)",
        "pathway_count": 1,
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        "publication_id_list": "",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021325545.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 3,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 3,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
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        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "reported_mutagensis": 0,
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        "reported_snv": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity;GO:0031267 small GTPase binding",
        "go_cellular_component": "GO:0005829 cytosol",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A8M9PWN4-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.010000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M9PTA8-1",
        "uniprot_id": [
            {
                "id": "A0A8M9PTA8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9PTA8",
                "type": "external"
            }
        ],
        "mass": 25941.0,
        "length": 232,
        "protein_name": "Platelet glycoprotein IX precursor",
        "gene_name": "gp9",
        "organism": "Zebrafish",
        "refseq_name": "platelet glycoprotein IX precursor",
        "refseq_ac": [
            {
                "id": "NP_001373473",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373473",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "gp9; si:ch1073-66c17.4",
        "gene_names_refseq": "gp9; si:ch1073-66c17.4",
        "protein_names_uniprotkb": "Platelet glycoprotein IX precursor",
        "protein_names_refseq": "platelet glycoprotein IX precursor",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100322009)",
        "pathway_count": 1,
        "publication_count": 4,
        "publication_id_list": "26469318;27189481;27811851;34407604",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01035375.1, GDQH01025486.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1. On Aug 29, 2020 this sequence version replaced XP_009294882.1. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
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        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "glyco_site_count": 0,
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0016020 membrane",
        "go_biological_process": "GO:0007155 cell adhesion;GO:0007596 blood coagulation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.5,
        "record_id": "A0A8M9PTA8-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A8M9PTB0_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9PTB0",
                "type": "external"
            }
        ],
        "mass": 48312.0,
        "length": 433,
        "protein_name": "Phospholipase B1, membrane-associated",
        "gene_name": "si:dkey-177p2.18",
        "organism": "Zebrafish",
        "refseq_name": "phospholipase B1, membrane-associated isoform X1",
        "refseq_ac": [
            {
                "id": "XP_021324310",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324310",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:dkey-177p2.18",
        "gene_names_refseq": "si:dkey-177p2.18",
        "protein_names_uniprotkb": "Phospholipase B1, membrane-associated; 3.1.1.3; 3.1.1.4; 3.1.1.5; Lysophospholipase; Phospholipase A2; Phospholipase B/lipase; Triacylglycerol lipase",
        "protein_names_refseq": "phospholipase B1, membrane-associated isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:101886068)",
        "pathway_count": 1,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021324310.1. COMPLETENESS: full length., [RefSeq]; Calcium-independent membrane-associated phospholipase that catalyzes complete diacylation of phospholipids by hydrolyzing both sn-1 and sn-2 fatty acyl chains attached to the glycerol backbone (phospholipase B activity). Has dual phospholipase and lysophospholipase activities toward diacylphospholipids. Preferentially cleaves sn-2 ester bonds over sn-1 bonds. Acts as a lipase toward glycerolipid substrates. Hydrolyzes fatty acyl chains of diacylglycerols with preference for the sn-2 position and of triacylglycerols with not positional selectivity. May also hydrolyze long chain retinyl esters such as retinyl palmitate. May contribute to digestion of dietary phospholipids, glycerolipids and retinoids, facilitating lipid absorption at the brush border., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
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        "predicted_o_glycosites": 1,
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        "predicted_s_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": [
            {
                "id": "3.1.1.34",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.34",
                "type": "external"
            },
            {
                "id": "3.1.1.32",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32",
                "type": "external"
            },
            {
                "id": "3.1.1.4",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4",
                "type": "external"
            },
            {
                "id": "2.3.1.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-",
                "type": "external"
            },
            {
                "id": "3.1.1.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.-",
                "type": "external"
            },
            {
                "id": "3.1.1.5",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5",
                "type": "external"
            },
            {
                "id": "3.1.1.23",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.23",
                "type": "external"
            },
            {
                "id": "3.1.1.79",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.79",
                "type": "external"
            },
            {
                "id": "3.1.1.3",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3",
                "type": "external"
            },
            {
                "id": "3.1.1.116",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.116",
                "type": "external"
            },
            {
                "id": "3.1.1.6",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.6",
                "type": "external"
            },
            {
                "id": "3.1.-.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0004622 phosphatidylcholine lysophospholipase activity;GO:0004623 phospholipase A2 activity;GO:0004806 triacylglycerol lipase activity;GO:0050253 retinyl-palmitate esterase activity",
        "go_cellular_component": "GO:0031526 brush border membrane",
        "go_biological_process": "GO:0006644 phospholipid metabolic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A8M9PTB0-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M9PTL2-1",
        "uniprot_id": [
            {
                "id": "A0A8M9PTL2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9PTL2",
                "type": "external"
            }
        ],
        "mass": 25091.0,
        "length": 237,
        "protein_name": "Complement C1q-like protein 4",
        "gene_name": "c1ql4a",
        "organism": "Zebrafish",
        "refseq_name": "complement C1q-like protein 4",
        "refseq_ac": [
            {
                "id": "XP_021325666",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325666",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "c1ql4a",
        "gene_names_refseq": "c1ql4a",
        "protein_names_uniprotkb": "Complement C1q-like protein 4",
        "protein_names_refseq": "complement C1q-like protein 4",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:559288)",
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        "gene_name": "LOC566011",
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        "protein_names_refseq": "novel serine protease protein; uncharacterized protein LOC100003428 isoform 1",
        "tax_id": 7955,
        "disease": "3-methylglutaconic aciduria type 8 (Disease Ontology:DOID:0070000); prostate cancer (Disease Ontology:DOID:10283); stomach cancer (Disease Ontology:DOID:10534); Alzheimer's disease (Disease Ontology:DOID:10652); asphyxia neonatorum (Disease Ontology:DOID:11088); cryptorchidism (Disease Ontology:DOID:11383); endometrial cancer (Disease Ontology:DOID:1380); Parkinson's disease (Disease Ontology:DOID:14330); status epilepticus (Disease Ontology:DOID:1824); transient cerebral ischemia (Disease Ontology:DOID:224); motor neuron disease (Disease Ontology:DOID:231); ovarian cancer (Disease Ontology:DOID:2394); middle cerebral artery infarction (Disease Ontology:DOID:3525); colorectal cancer (Disease Ontology:DOID:9256)",
        "pathway": " (dre:100003428)",
        "pathway_count": 1,
        "publication_count": 1,
        "publication_id_list": "28252024",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588731.2877747.1, SRR32588720.1038762.1 [ECO:0000332] RNAseq introns :: partial sample support SAMN18715719, SAMN18715720 [ECO:0000350] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1. On Dec 5, 2025 this sequence version replaced NP_001098612.2., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "reported_mutagensis": 0,
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        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 14,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0004252 serine-type endopeptidase activity",
        "go_cellular_component": "GO:0005739 mitochondrion",
        "go_biological_process": "GO:0006508 proteolysis;GO:0043065 positive regulation of apoptotic process;GO:0012501 programmed cell death",
        "synthesized_glycan_count": 0,
        "hit_score": 0.2,
        "record_id": "A0A8M9PTZ3-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M9PTZ5-1",
        "uniprot_id": [
            {
                "id": "A0A8M9PTZ5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9PTZ5",
                "type": "external"
            }
        ],
        "mass": 85689.0,
        "length": 829,
        "protein_name": "LOW QUALITY PROTEIN: uncharacterized protein",
        "gene_name": "LOC100332822",
        "organism": "Zebrafish",
        "refseq_name": "LOW QUALITY PROTEIN: uncharacterized protein",
        "refseq_ac": [
            {
                "id": "XP_021334992",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021334992",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC100332822",
        "gene_names_refseq": "LOC100332822",
        "protein_names_uniprotkb": "LOW QUALITY PROTEIN: uncharacterized protein",
        "protein_names_refseq": "LOW QUALITY PROTEIN: uncharacterized protein",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100332822)",
        "pathway_count": 1,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts                 :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021334992.2. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "missing_score": 10000,
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        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
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        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
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    {
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            {
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                "url": "https://www.uniprot.org/uniprot/A0A8M9PUA0",
                "type": "external"
            }
        ],
        "mass": 37709.0,
        "length": 327,
        "protein_name": "Probable G-protein coupled receptor 174",
        "gene_name": "gpr174",
        "organism": "Zebrafish",
        "refseq_name": "probable G-protein coupled receptor 174",
        "refseq_ac": [
            {
                "id": "XP_005157230",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157230",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "gpr174",
        "gene_names_refseq": "gpr174",
        "protein_names_uniprotkb": "Probable G-protein coupled receptor 174",
        "protein_names_refseq": "probable G-protein coupled receptor 174",
        "tax_id": 7955,
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        "pathway": " (dre:100151331)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "secondary_ac_list": "A0A0R4IQ80",
        "ec_number_list": [],
        "go_molecular_function": "GO:0004930 G protein-coupled receptor activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M9PUA2-1",
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            {
                "id": "A0A8M9PUA2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9PUA2",
                "type": "external"
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        ],
        "mass": 61938.0,
        "length": 546,
        "protein_name": "NXPE family member 3 isoform X1",
        "gene_name": "si:ch211-157j23.2",
        "organism": "Zebrafish",
        "refseq_name": "NXPE family member 3 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_021325936",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325936",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "si:ch211-157j23.2",
        "gene_names_refseq": "si:ch211-157j23.2",
        "protein_names_uniprotkb": "NXPE family member 3 isoform X1",
        "protein_names_refseq": "NXPE family member 3 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:327475)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021325936.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "mined_n_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "total_reported_n_glycosites": 0,
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        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
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        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "GO:0007399 nervous system development",
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        "hit_score": 0.1,
        "record_id": "A0A8M9PUA2-1",
        "record_type": "protein",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M9PUC5-1",
        "uniprot_id": [
            {
                "id": "A0A8M9PUC5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9PUC5",
                "type": "external"
            }
        ],
        "mass": 36132.0,
        "length": 314,
        "protein_name": "Uracil nucleotide/cysteinyl leukotriene receptor",
        "gene_name": "si:dkey-96n2.3",
        "organism": "Zebrafish",
        "refseq_name": "uracil nucleotide/cysteinyl leukotriene receptor",
        "refseq_ac": [
            {
                "id": "XP_021325961",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325961",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:dkey-96n2.3",
        "gene_names_refseq": "si:dkey-96n2.3",
        "protein_names_uniprotkb": "Uracil nucleotide/cysteinyl leukotriene receptor; G-protein coupled receptor 17",
        "protein_names_refseq": "uracil nucleotide/cysteinyl leukotriene receptor",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100001258)",
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        "publication_id_list": "",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "go_molecular_function": "GO:0004930 G protein-coupled receptor activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
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        "record_type": "protein",
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        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A8M9PUC9_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9PUC9",
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        ],
        "mass": 271322.0,
        "length": 2385,
        "protein_name": "Lipoxygenase homology domain-containing protein 1",
        "gene_name": "loxhd1a",
        "organism": "Zebrafish",
        "refseq_name": "lipoxygenase homology domain-containing protein 1",
        "refseq_ac": [
            {
                "id": "XP_021324660",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324660",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "loxhd1a",
        "gene_names_refseq": "loxhd1a",
        "protein_names_uniprotkb": "Lipoxygenase homology domain-containing protein 1",
        "protein_names_refseq": "lipoxygenase homology domain-containing protein 1",
        "tax_id": 7955,
        "disease": "orofacial cleft (Disease Ontology:DOID:0050567); autosomal recessive nonsyndromic deafness 77 (Disease Ontology:DOID:0110525); Fuchs' endothelial dystrophy (Disease Ontology:DOID:11555)",
        "pathway": " (dre:564819)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021324660.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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    {
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            {
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        ],
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        ],
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        "protein_names_refseq": "mitogen-activated protein kinase kinase kinase 14 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0004672 protein kinase activity;GO:0005524 ATP binding;GO:0016301 kinase activity",
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        "go_biological_process": "GO:0000165 MAPK cascade;GO:0035556 intracellular signal transduction",
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    {
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        "mass": 153819.0,
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        "protein_name": "Fanconi anemia group I protein isoform X1",
        "gene_name": "fanci",
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        "refseq_ac": [
            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326126",
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        "gene_names_refseq": "fanci; fc21c10; wu:fc21c10; zgc:152941",
        "protein_names_uniprotkb": "Fanconi anemia group I protein isoform X1",
        "protein_names_refseq": "Fanconi anemia group I protein isoform X1",
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        "pathway": " (dre:324185)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "Flap endonuclease GEN homolog 1",
        "gene_name": "gen1",
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        "protein_names_refseq": "flap endonuclease GEN homolog 1 isoform X2",
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        "predicted_glycosites": 0,
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        ],
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        "protein_name": "Neuronal acetylcholine receptor subunit alpha-10 isoform X2",
        "gene_name": "chrna10b",
        "organism": "Zebrafish",
        "refseq_name": "neuronal acetylcholine receptor subunit alpha-10 isoform X2",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324910",
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        "gene_names_refseq": "LOC101882637",
        "protein_names_uniprotkb": "Neuronal acetylcholine receptor subunit alpha-10 isoform X2",
        "protein_names_refseq": "neuronal acetylcholine receptor subunit alpha-10 isoform X2",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_cellular_component": "GO:0005886 plasma membrane;GO:0005892 acetylcholine-gated channel complex;GO:0045202 synapse;GO:0045211 postsynaptic membrane;GO:0043005 neuron projection",
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        "gene_name": "LOC101884203",
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        ],
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        "length": 443,
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        "gene_name": "si:dkey-219e21.2",
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        "tax_id": 7955,
        "disease": "myelodysplastic syndrome (Disease Ontology:DOID:0050908); Sweet syndrome (Disease Ontology:DOID:0080746); IgA vasculitis (Disease Ontology:DOID:11123); asthma (Disease Ontology:DOID:2841); familial Mediterranean fever (Disease Ontology:DOID:2987); lung disease (Disease Ontology:DOID:850); acute myeloid leukemia (Disease Ontology:DOID:9119); multiple myeloma (Disease Ontology:DOID:9538); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_names_refseq": "uncharacterized protein zmp:0000000991 isoform X1",
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        "protein_names_refseq": "intraflagellar transport protein 140 homolog isoform X1",
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        "disease": "retinitis pigmentosa 80 (Disease Ontology:DOID:0061111); asphyxiating thoracic dystrophy 1 (Disease Ontology:DOID:0110085); short-rib thoracic dysplasia 9 with or without polydactyly (Disease Ontology:DOID:0110097)",
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        "protein_name": "Uncharacterized aarF domain-containing protein kinase 2",
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        ],
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            {
                "id": "XP_021337099",
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        "pathway": " (dre:561339)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021329596.1. COMPLETENESS: full length., [RefSeq]",
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        "protein_names_refseq": "ribonucleoprotein PTB-binding 1 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cooperates with PTBP1 to modulate regulated alternative splicing events. Promotes exon skipping. Cooperates with PTBP1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA., [UniProtKB, UniProtKB, UniProtKB]",
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        "gene_name": "mcc",
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            {
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    },
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        ],
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        "protein_name": "Adhesion G protein-coupled receptor E3 isoform X1",
        "gene_name": "adgre14",
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        "refseq_name": "adhesion G protein-coupled receptor E3 isoform X1",
        "refseq_ac": [
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        ],
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        "gene_name": "zdbf2",
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        "gene_names_uniprotkb": "zdbf2; adam23a",
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        "gene_names_refseq": "si:ch73-109d9.1",
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        ],
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        "gene_name": "dok2l",
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        "gene_names_uniprotkb": "dok2l",
        "gene_names_refseq": "dok2l",
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        "protein_names_refseq": "docking protein 1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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            {
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        "protein_names_uniprotkb": "Caspase recruitment domain-containing protein 14",
        "protein_names_refseq": "caspase recruitment domain-containing protein 14",
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        "disease": "psoriasis 2 (Disease Ontology:DOID:0080475); pityriasis rubra pilaris (Disease Ontology:DOID:9212)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Acts as a scaffolding protein that can activate the inflammatory transcription factor NF-kappa-B and p38/JNK MAP kinase signaling pathways. Forms a signaling complex with BCL10 and MALT1, and activates MALT1 proteolytic activity and inflammatory gene expression. MALT1 is indispensable for CARD14-induced activation of NF-kappa-B and p38/JNK MAP kinases. May play a role in signaling mediated by TRAF2, TRAF3 and TRAF6 and protects cells against apoptosis., [UniProtKB, UniProtKB]",
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        "protein_names_uniprotkb": "Junctional cadherin 5-associated protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021330824.1. COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]",
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            {
                "id": "XP_021331054",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio                   :: 17% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        ],
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        "protein_name": "Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein",
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        "protein_names_refseq": "carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021327300.1. COMPLETENESS: full length., [RefSeq]; Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level. Mediates an indirect interaction between NOS1 and RASD1 leading to enhance the ability of NOS1 to activate RASD1. Competes with DLG4 for interaction with NOS1, possibly affecting NOS1 activity by regulating the interaction between NOS1 and DLG4. In kidney podocytes, plays a role in podosomes and filopodia formation through CDC42 activation., [UniProtKB, UniProtKB, UniProtKB]",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "reported_phosphosites": 0,
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        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0017147 Wnt-protein binding",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0021782 glial cell development;GO:0060041 retina development in camera-type eye;GO:0030178 negative regulation of Wnt signaling pathway",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A8M9Q271-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M9Q291-1",
        "uniprot_id": [
            {
                "id": "A0A8M9Q291_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9Q291",
                "type": "external"
            }
        ],
        "mass": 46010.0,
        "length": 401,
        "protein_name": "C2H2-type domain-containing protein",
        "gene_name": "LOC110439614",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "XP_021331434",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331434",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC110439614",
        "gene_names_refseq": "LOC110439614",
        "protein_names_uniprotkb": "C2H2-type domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:110439614)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021331434.1. COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
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        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
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        "total_reported_n_glycosites": 0,
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        "reported_mutagensis": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "secondary_ac_list": "A0AC58JBF8;A0AC58JBG8",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A8M9Q291-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M9Q2D4-1",
        "uniprot_id": [
            {
                "id": "A0A8M9Q2D4_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9Q2D4",
                "type": "external"
            }
        ],
        "mass": 36780.0,
        "length": 330,
        "protein_name": "Lysophosphatidic acid receptor 6",
        "gene_name": "si:dkey-3k24.8",
        "organism": "Zebrafish",
        "refseq_name": "lysophosphatidic acid receptor 6",
        "refseq_ac": [
            {
                "id": "XP_021333483",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333483",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:dkey-3k24.8",
        "gene_names_refseq": "si:dkey-3k24.8",
        "protein_names_uniprotkb": "Lysophosphatidic acid receptor 6",
        "protein_names_refseq": "lysophosphatidic acid receptor 6",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:110437788)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
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        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "total_reported_n_glycosites": 0,
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        "reported_snv": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0004930 G protein-coupled receptor activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway",
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        "hit_score": 0.1,
        "record_id": "A0A8M9Q2D4-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M9Q2K2-1",
        "uniprot_id": [
            {
                "id": "A0A8M9Q2K2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9Q2K2",
                "type": "external"
            }
        ],
        "mass": 46102.0,
        "length": 405,
        "protein_name": "B-cell receptor CD22",
        "gene_name": "LOC110439716",
        "organism": "Zebrafish",
        "refseq_name": "sialic acid-binding Ig-like lectin 14",
        "refseq_ac": [
            {
                "id": "XP_021331569",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331569",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC110439716",
        "gene_names_refseq": "LOC110439716",
        "protein_names_uniprotkb": "B-cell receptor CD22; Sialic acid-binding Ig-like lectin 2",
        "protein_names_refseq": "sialic acid-binding Ig-like lectin 14",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:110439716)",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021331569.1. COMPLETENESS: full length., [RefSeq]; Most highly expressed siglec (sialic acid-binding immunoglobulin-like lectin) on B-cells that plays a role in various aspects of B-cell biology including differentiation, antigen presentation, and trafficking to bone marrow. Binds to alpha 2,6-linked sialic acid residues of surface molecules such as CD22 itself, CD45 and IgM in a cis configuration. Can also bind to ligands on other cells as an adhesion molecule in a trans configuration. Acts as an inhibitory coreceptor on the surface of B-cells and inhibits B-cell receptor induced signaling, characterized by inhibition of the calcium mobilization and cellular activation. Mechanistically, the immunoreceptor tyrosine-based inhibitory motif domain is phosphorylated by the Src kinase LYN, which in turn leads to the recruitment of the protein tyrosine phosphatase 1/PTPN6, leading to the negative regulation of BCR signaling. If this negative signaling from is of sufficient strength, apoptosis of the B-cell can be induced., [UniProtKB, UniProtKB]",
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        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
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        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A8M9Q2K2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M9Q2M7-1",
        "uniprot_id": [
            {
                "id": "A0A8M9Q2M7_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9Q2M7",
                "type": "external"
            }
        ],
        "mass": 53119.0,
        "length": 466,
        "protein_name": "Olfactomedin-4",
        "gene_name": "olfm4.2",
        "organism": "Zebrafish",
        "refseq_name": "olfactomedin-4",
        "refseq_ac": [
            {
                "id": "XP_021328891",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328891",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "olfm4.2; olfm4.1",
        "gene_names_refseq": "olfm4.2",
        "protein_names_uniprotkb": "Olfactomedin-4",
        "protein_names_refseq": "olfactomedin-4",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:569381)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021328891.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
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        "mined_glycosites": 0,
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        "mined_o_glycosites": 0,
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        "reported_n_glycosites": 0,
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        "reported_c_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
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        "reported_phosphosites": 0,
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        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "secondary_ac_list": "",
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        "go_molecular_function": "",
        "go_cellular_component": "GO:0005615 extracellular space",
        "go_biological_process": "GO:0007165 signal transduction",
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        "hit_score": 0.1,
        "record_id": "A0A8M9Q2M7-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A8M9Q2N5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9Q2N5",
                "type": "external"
            }
        ],
        "mass": 48659.0,
        "length": 420,
        "protein_name": "AIG1-type G domain-containing protein",
        "gene_name": "LOC560949",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "XP_021327705",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327705",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC560949",
        "gene_names_refseq": "LOC560949",
        "protein_names_uniprotkb": "AIG1-type G domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:560949)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021327705.2. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "mined_c_glycosites": 0,
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        "reported_mutagensis": 0,
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        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
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        "binding_glycan_count": 0,
        "secondary_ac_list": "",
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        "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A8M9Q2N5-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A8M9Q2Q4_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9Q2Q4",
                "type": "external"
            }
        ],
        "mass": 28728.0,
        "length": 259,
        "protein_name": "Protein PERCC1",
        "gene_name": "percc1",
        "organism": "Zebrafish",
        "refseq_name": "protein PERCC1",
        "refseq_ac": [
            {
                "id": "XP_021331624",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331624",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "percc1",
        "gene_names_refseq": "percc1",
        "protein_names_uniprotkb": "Protein PERCC1",
        "protein_names_refseq": "protein PERCC1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:110439781)",
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        "publication_count": 0,
        "publication_id_list": "",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        ],
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        "length": 228,
        "protein_name": "Uncharacterized protein LOC569751 precursor",
        "gene_name": "si:dkey-261l7.2",
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        "refseq_name": "uncharacterized protein LOC569751",
        "refseq_ac": [
            {
                "id": "NP_001373437",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373437",
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        "gene_names_uniprotkb": "si:dkey-261l7.2",
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        "protein_name": "A-type potassium channel modulatory protein KCNIP2",
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        "gene_names_refseq": "LOC101886535",
        "protein_names_uniprotkb": "A-type potassium channel modulatory protein KCNIP2",
        "protein_names_refseq": "A-type potassium channel modulatory protein KCNIP2",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions., [UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0015459 potassium channel regulator activity;GO:0005509 calcium ion binding",
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        "protein_name": "Uncharacterized protein si:dkey-49o11.1",
        "gene_name": "si:dkey-49o11.1",
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        "refseq_name": "uncharacterized protein si:dkey-49o11.1",
        "refseq_ac": [
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        "gene_names_refseq": "si:dkey-49o11.1",
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        "tax_id": 7955,
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        "predicted_glycosites": 0,
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        "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 isoform X1",
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        "gene_names_refseq": "pip5kl1",
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        "protein_names_refseq": "phosphatidylinositol 4-phosphate 5-kinase-like protein 1 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0005524 ATP binding;GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity;GO:0052742 phosphatidylinositol kinase activity",
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                "url": "https://www.uniprot.org/uniprot/A0A8M9Q541",
                "type": "external"
            }
        ],
        "mass": 15397.0,
        "length": 133,
        "protein_name": "Uncharacterized protein",
        "gene_name": "LOC100320750",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "XP_021323482",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323482",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC100320750",
        "gene_names_refseq": "LOC100320750",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100320750)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "reported_mutagensis": 0,
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        "missing_score": 10000,
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        "synthesized_glycan_count": 0,
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        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M9Q575-1",
        "uniprot_id": [
            {
                "id": "A0A8M9Q575_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9Q575",
                "type": "external"
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        ],
        "mass": 30127.0,
        "length": 273,
        "protein_name": "Granzyme-like protein 1",
        "gene_name": "si:dkey-21e2.13",
        "organism": "Zebrafish",
        "refseq_name": "granzyme-like protein 1",
        "refseq_ac": [
            {
                "id": "XP_021330146",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021330146",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "si:dkey-21e2.13",
        "gene_names_refseq": "si:dkey-21e2.13",
        "protein_names_uniprotkb": "Granzyme-like protein 1",
        "protein_names_refseq": "granzyme-like protein 1",
        "tax_id": 7955,
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        "pathway": " (dre:556666)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021330146.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0004252 serine-type endopeptidase activity",
        "go_cellular_component": "GO:0005615 extracellular space",
        "go_biological_process": "GO:0006508 proteolysis;GO:0051604 protein maturation",
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        "record_type": "protein",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M9Q5G7-1",
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            {
                "id": "A0A8M9Q5G7_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9Q5G7",
                "type": "external"
            }
        ],
        "mass": 81813.0,
        "length": 729,
        "protein_name": "phospholipase A2",
        "gene_name": "proca1",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein proca1",
        "refseq_ac": [
            {
                "id": "XP_009289846",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009289846",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "proca1",
        "gene_names_refseq": "proca1",
        "protein_names_uniprotkb": "phospholipase A2; 3.1.1.4",
        "protein_names_refseq": "uncharacterized protein proca1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "secondary_ac_list": "E7F6W0",
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        "go_molecular_function": "GO:0046872 metal ion binding;GO:0004623 phospholipase A2 activity",
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        "go_biological_process": "GO:0050482 arachidonate secretion;GO:0006644 phospholipid metabolic process",
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        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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            {
                "id": "A0A8M9Q5P8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9Q5P8",
                "type": "external"
            }
        ],
        "mass": 37290.0,
        "length": 320,
        "protein_name": "C2H2-type domain-containing protein",
        "gene_name": "LOC798120",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "XP_021330556",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021330556",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC798120",
        "gene_names_refseq": "LOC798120",
        "protein_names_uniprotkb": "C2H2-type domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:798120)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A8M9Q5P8-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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                "url": "https://www.uniprot.org/uniprot/A0A8M9Q5Q6",
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            }
        ],
        "mass": 67231.0,
        "length": 595,
        "protein_name": "Interleukin-1 receptor-like 1 isoform X1",
        "gene_name": "il1rl1",
        "organism": "Zebrafish",
        "refseq_name": "interleukin-1 receptor-like 1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_021334743",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021334743",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "il1rl1",
        "gene_names_refseq": "il1rl1",
        "protein_names_uniprotkb": "Interleukin-1 receptor-like 1 isoform X1",
        "protein_names_refseq": "interleukin-1 receptor-like 1 isoform X1",
        "tax_id": 7955,
        "disease": "idiopathic pulmonary fibrosis (Disease Ontology:DOID:0050156); obstructive sleep apnea (Disease Ontology:DOID:0050848); tongue squamous cell carcinoma (Disease Ontology:DOID:0050865); acute asthma (Disease Ontology:DOID:0080810); Human papillomavirus infectious disease (Disease Ontology:DOID:11166); Hantavirus hemorrhagic fever with renal syndrome (Disease Ontology:DOID:11266); hemolytic-uremic syndrome (Disease Ontology:DOID:12554); paracoccidioidomycosis (Disease Ontology:DOID:12662); asthma (Disease Ontology:DOID:2841); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); coronary artery disease (Disease Ontology:DOID:3393); pulmonary hypertension (Disease Ontology:DOID:6432); lung disease (Disease Ontology:DOID:850); bacterial pneumonia (Disease Ontology:DOID:874); acute myocardial infarction (Disease Ontology:DOID:9408); allergic asthma (Disease Ontology:DOID:9415)",
        "pathway": " (dre:407649)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021334743.2. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0016787 hydrolase activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface",
        "go_biological_process": "GO:0007166 cell surface receptor signaling pathway",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A8M9Q5Q6-1",
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        "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        ],
        "mass": 328343.0,
        "length": 2929,
        "protein_name": "Obscurin-like protein 1",
        "gene_name": "obsl1b",
        "organism": "Zebrafish",
        "refseq_name": "obscurin isoform X1",
        "refseq_ac": [
            {
                "id": "XP_021334748",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021334748",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "obsl1b",
        "gene_names_refseq": "obsl1b",
        "protein_names_uniprotkb": "Obscurin-like protein 1",
        "protein_names_refseq": "obscurin isoform X1",
        "tax_id": 7955,
        "disease": "3-M syndrome (Disease Ontology:DOID:0060241)",
        "pathway": " (dre:606585)",
        "pathway_count": 1,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer. Acts as a regulator of the Cul7-RING(FBXW8) ubiquitin-protein ligase, playing a critical role in the ubiquitin ligase pathway that regulates Golgi morphogenesis and dendrite patterning in brain. Required to localize CUL7 to the Golgi apparatus in neurons., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0003676 nucleic acid binding",
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        "go_biological_process": "GO:0015074 DNA integration",
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        "filter_code": "0000000.0000001.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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            {
                "id": "A0A8M9Q6H5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9Q6H5",
                "type": "external"
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        ],
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        "length": 468,
        "protein_name": "CARD domain-containing protein",
        "gene_name": "LOC110437810",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "XP_021331011",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331011",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC110437810",
        "gene_names_refseq": "LOC110437810",
        "protein_names_uniprotkb": "CARD domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:110437810)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021331011.2. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_biological_process": "GO:0042981 regulation of apoptotic process",
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        "record_id": "A0A8M9Q6H5-1",
        "record_type": "protein",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M9Q6P7-1",
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            {
                "id": "A0A8M9Q6P7_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9Q6P7",
                "type": "external"
            }
        ],
        "mass": 41460.0,
        "length": 389,
        "protein_name": "Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D",
        "gene_name": "LOC101884942",
        "organism": "Zebrafish",
        "refseq_name": "soluble scavenger receptor cysteine-rich domain-containing protein SSC5D isoform X1",
        "refseq_ac": [
            {
                "id": "XP_021331096",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331096",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC101884942",
        "gene_names_refseq": "LOC101884942",
        "protein_names_uniprotkb": "Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D",
        "protein_names_refseq": "soluble scavenger receptor cysteine-rich domain-containing protein SSC5D isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:101884942)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021331096.2. COMPLETENESS: full length., [RefSeq]; Binds to extracellular matrix proteins. Binds to pathogen-associated molecular patterns (PAMPs) present on the cell walls of Gram-positive and Gram-negative bacteria and fungi, behaving as a pattern recognition receptor (PRR). Induces bacterial and fungal aggregation and subsequent inhibition of PAMP-induced cytokine release. Does not possess intrinsic bactericidal activity. May play a role in the innate defense and homeostasis of certain epithelial surfaces., [UniProtKB, UniProtKB]",
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        "missing_score": 10000,
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        "go_molecular_function": "",
        "go_cellular_component": "GO:0016020 membrane",
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    },
    {
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            {
                "id": "A0A8M9Q6S3_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9Q6S3",
                "type": "external"
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        ],
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        "length": 667,
        "protein_name": "RNA 2',3'-cyclic phosphatase ANGEL1",
        "gene_name": "angel1",
        "organism": "Zebrafish",
        "refseq_name": "protein angel homolog 2",
        "refseq_ac": [
            {
                "id": "XP_021328890",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328890",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "angel1",
        "gene_names_refseq": "angel1",
        "protein_names_uniprotkb": "RNA 2',3'-cyclic phosphatase ANGEL1",
        "protein_names_refseq": "protein angel homolog 2",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:569547)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021328890.1. COMPLETENESS: full length., [RefSeq]; Exhibits weak RNA 2',3'-cyclic phosphatase, catalyzing the hydrolysis of RNA molecules with a 2',3'-cyclic phosphate at the 3' end to produce RNA with a linear 3'-phosphate group. Plays a role in the non-stop mRNA decay pathway (NSD), which specifically targets and degrades mRNAs that lack a proper stop codon., [UniProtKB, UniProtKB]",
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        "ec_number_list": [
            {
                "id": "3.-.-.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.-.-.-",
                "type": "external"
            }
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    {
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                "url": "https://www.uniprot.org/uniprot/A0A8M9Q6S8",
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        ],
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        "length": 420,
        "protein_name": "C2H2-type domain-containing protein",
        "gene_name": "LOC110439430",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
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            {
                "id": "XP_021331131",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331131",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC110439430",
        "gene_names_refseq": "LOC110439430",
        "protein_names_uniprotkb": "C2H2-type domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:110439430)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021331131.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "predicted_o_glycosites": 0,
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        "secondary_ac_list": "A0AC58JBD2",
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        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II",
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        "kg_view_protein": true
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    {
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                "url": "https://www.uniprot.org/uniprot/A0A8M9Q6T4",
                "type": "external"
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        ],
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        "protein_name": "Ephexin-1",
        "gene_name": "LOC101882153",
        "organism": "Zebrafish",
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        "refseq_ac": [
            {
                "id": "XP_021332789",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332789",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC101882153",
        "gene_names_refseq": "LOC101882153",
        "protein_names_uniprotkb": "Ephexin-1",
        "protein_names_refseq": "ephexin-1",
        "tax_id": 7955,
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        "pathway": " (dre:101882153)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "secondary_ac_list": "A0AC58JUQ3",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity",
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        "go_biological_process": "GO:0032956 regulation of actin cytoskeleton organization",
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        ],
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        "protein_name": "NACHT, LRR and PYD domains-containing protein 3-like isoform X1",
        "gene_name": "LOC100334677",
        "organism": "Zebrafish",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "LOC100334677",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "NACHT, LRR and PYD domains-containing protein 3-like isoform X1",
        "protein_names_refseq": "",
        "tax_id": 7955,
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        "gene_name": "LOC110439530",
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                "id": "XP_021331316",
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        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
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        ],
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        "length": 515,
        "protein_name": "Potassium voltage-gated channel subfamily A member 3",
        "gene_name": "kcna3a",
        "organism": "Zebrafish",
        "refseq_name": "potassium voltage-gated channel subfamily A member 3",
        "refseq_ac": [
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        "gene_names_refseq": "kcna3a",
        "protein_names_uniprotkb": "Potassium voltage-gated channel subfamily A member 3",
        "protein_names_refseq": "potassium voltage-gated channel subfamily A member 3",
        "tax_id": 7955,
        "disease": "episodic ataxia type 1 (Disease Ontology:DOID:0050989); hypertension (Disease Ontology:DOID:10763); epilepsy (Disease Ontology:DOID:1826)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331366",
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        ],
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        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021331366.1. COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331371",
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        ],
        "gene_names_uniprotkb": "LOC110439562",
        "gene_names_refseq": "LOC110439562",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021331371.2. COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]",
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                "url": "https://www.uniprot.org/uniprot/A0A8M9Q7D5",
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            }
        ],
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        "protein_name": "Duodenase-1",
        "gene_name": "si:dkey-21e2.10",
        "organism": "Zebrafish",
        "refseq_name": "trypsin-like serine protease domain-containing protein precursor",
        "refseq_ac": [
            {
                "id": "NP_001428470",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001428470",
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        "gene_names_uniprotkb": "si:dkey-21e2.10",
        "gene_names_refseq": "si:dkey-21e2.10",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01037095.1, GDQQ01001875.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476786, SAMEA708836 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1. On Jun 13, 2025 this sequence version replaced XP_021329145.1., [RefSeq]",
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        "gene_names_uniprotkb": "LOC110439069; LOC110439065; LOC141380309",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "protein_name": "Protein FAM13C isoform X1",
        "gene_name": "fam13c; si:ch73-51i5.2",
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        "refseq_name": "si:ch73-51i5.2",
        "refseq_ac": [
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        "kg_view_protein": true
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    {
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        ],
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        "length": 345,
        "protein_name": "G protein-coupled receptor 88",
        "gene_name": "gpr88",
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        "refseq_name": "G protein-coupled receptor 88",
        "refseq_ac": [
            {
                "id": "NP_001373756",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373756",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "gpr88; fj63d09; wu:fj63d09",
        "gene_names_refseq": "fj63d09; gpr88; wu:fj63d09",
        "protein_names_uniprotkb": "G protein-coupled receptor 88",
        "protein_names_refseq": "G protein-coupled receptor 88",
        "tax_id": 7955,
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        "publication_id_list": "22046030",
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        "function": "VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1. On Nov 28, 2025 this sequence version replaced NP_001373756.1., [RefSeq]",
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        "go_molecular_function": "GO:0008020 G protein-coupled photoreceptor activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007602 phototransduction;GO:0071482 cellular response to light stimulus",
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        ],
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        "length": 1718,
        "protein_name": "Uncharacterized protein si:dkey-21p1.3",
        "gene_name": "si:dkey-21p1.3",
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        "refseq_name": "uncharacterized protein si:dkey-21p1.3",
        "refseq_ac": [
            {
                "id": "XP_021334064",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021334064",
                "type": "external"
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        "gene_names_uniprotkb": "si:dkey-21p1.3",
        "gene_names_refseq": "si:dkey-21p1.3",
        "protein_names_uniprotkb": "Uncharacterized protein si:dkey-21p1.3",
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        "tax_id": 7955,
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        "pathway": " (dre:101883345)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021334064.2. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "go_molecular_function": "GO:0030020 extracellular matrix structural constituent conferring tensile strength",
        "go_cellular_component": "GO:0031012 extracellular matrix;GO:0005594 collagen type IX trimer",
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        ],
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        "length": 513,
        "protein_name": "Uncharacterized protein LOC100535981",
        "gene_name": "si:ch211-250c4.3",
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        "refseq_ac": [
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        "gene_names_uniprotkb": "si:ch211-250c4.3; im:7140162; si:ch211-250c4.4",
        "gene_names_refseq": "im:7140162; si:ch211-250c4.3; si:ch211-250c4.4",
        "protein_names_uniprotkb": "Uncharacterized protein LOC100535981",
        "protein_names_refseq": "uncharacterized protein LOC100535981",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01019434.1, SRR32588718.14976332.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505373 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1. On Jun 25, 2025 this sequence version replaced NP_001352148.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
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        "secondary_ac_list": "F1R909",
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        ],
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        "protein_name": "Pyroglutamylated RF-amide peptide receptor",
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            {
                "id": "XP_021336543",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021336543",
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        "gene_names_refseq": "qrfpra",
        "protein_names_uniprotkb": "Pyroglutamylated RF-amide peptide receptor; AQ27; G-protein coupled receptor 103; Orexigenic neuropeptide QRFP receptor; SP9155",
        "protein_names_refseq": "pyroglutamylated RF-amide peptide receptor",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Receptor for the orexigenic neuropeptide QRFP. The activity of this receptor is mediated by G proteins that modulate adenylate cyclase activity and intracellular calcium levels., [UniProtKB, UniProtKB]",
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    {
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                "url": "https://www.uniprot.org/uniprot/A0A8M9QAF4",
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        ],
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        "length": 174,
        "protein_name": "E3 ubiquitin-protein ligase RBBP6",
        "gene_name": "si:dkey-27d5.13",
        "organism": "Zebrafish",
        "refseq_name": "E3 ubiquitin-protein ligase RBBP6",
        "refseq_ac": [
            {
                "id": "XP_021335438",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021335438",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "si:dkey-27d5.13",
        "gene_names_refseq": "si:dkey-27d5.13",
        "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RBBP6",
        "protein_names_refseq": "E3 ubiquitin-protein ligase RBBP6",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021335438.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006397 mRNA processing;GO:0016567 protein ubiquitination",
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        "kg_view_protein": true
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    {
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        ],
        "mass": 62444.0,
        "length": 555,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC110437875",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": [
            {
                "id": "XP_073803125",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073803125",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC110437875",
        "gene_names_refseq": "LOC110437875",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
        "disease": "",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "protein_name": "Alcohol dehydrogenase 6",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Alcohol dehydrogenase. Catalyzes the NAD-dependent oxidation of primary alcohols to the corresponding aldehydes. Oxidizes secondary alcohols to the corresponding ketones., [UniProtKB, UniProtKB, UniProtKB]",
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "reported_snv": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 5,
        "glyco_site_count": 1,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity",
        "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005813 centrosome;GO:0005929 cilium",
        "go_biological_process": "GO:0007601 visual perception;GO:0030030 cell projection organization",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A8M9QB02-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.010000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M9QB59-1",
        "uniprot_id": [
            {
                "id": "A0A8M9QB59_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9QB59",
                "type": "external"
            }
        ],
        "mass": 56457.0,
        "length": 505,
        "protein_name": "Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein",
        "gene_name": "nos1apa",
        "organism": "Zebrafish",
        "refseq_name": "carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein",
        "refseq_ac": [
            {
                "id": "XP_021332861",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332861",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "nos1apa",
        "gene_names_refseq": "nos1apa",
        "protein_names_uniprotkb": "Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein; C-terminal PDZ ligand of neuronal nitric oxide synthase protein; Nitric oxide synthase 1 adaptor protein",
        "protein_names_refseq": "carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein",
        "tax_id": 7955,
        "disease": "nephrotic syndrome type 22 (Disease Ontology:DOID:0112268); sciatic neuropathy (Disease Ontology:DOID:11446); Duchenne muscular dystrophy (Disease Ontology:DOID:11723); depressive disorder (Disease Ontology:DOID:1596); congestive heart failure (Disease Ontology:DOID:6000)",
        "pathway": " (dre:553539)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level. Mediates an indirect interaction between NOS1 and RASD1 leading to enhance the ability of NOS1 to activate RASD1. Competes with DLG4 for interaction with NOS1, possibly affecting NOS1 activity by regulating the interaction between NOS1 and DLG4. In kidney podocytes, plays a role in podosomes and filopodia formation through CDC42 activation., [UniProtKB, UniProtKB]",
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        "reported_mutagensis": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 0,
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0050998 nitric-oxide synthase binding",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A8M9QB59-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M9QB77-1",
        "uniprot_id": [
            {
                "id": "A0A8M9QB77_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9QB77",
                "type": "external"
            }
        ],
        "mass": 16369.0,
        "length": 139,
        "protein_name": "Uncharacterized protein LOC103911624",
        "gene_name": "fc50b12; wu:fc50b12",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein LOC103911624",
        "refseq_ac": [
            {
                "id": "NP_001353570",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001353570",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "fc50b12; wu:fc50b12; fc50b12; wu:fc50b12",
        "gene_names_refseq": "fc50b12; wu:fc50b12",
        "protein_names_uniprotkb": "Uncharacterized protein LOC103911624",
        "protein_names_refseq": "p53-induced death domain-containing protein 1; uncharacterized protein LOC103911624",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:103911624)",
        "pathway_count": 1,
        "publication_count": 1,
        "publication_id_list": "27189481",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01038717.1, GDQH01006215.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505384, SAMEA4476729 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000009.1. On or before Oct 13, 2018 this sequence version replaced XP_021330296.1, XP_021329826.1, XP_021334549.1, XP_021327819.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
        "predicted_glycosites": 0,
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        "predicted_o_glycosites": 0,
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        "missing_score": 10000,
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        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "GO:0007165 signal transduction",
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        "hit_score": 0.2,
        "record_id": "A0A8M9QB77-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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            {
                "id": "A0A8M9QBF7_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9QBF7",
                "type": "external"
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        ],
        "mass": 49010.0,
        "length": 436,
        "protein_name": "Synaptotagmin",
        "gene_name": "syt2b",
        "organism": "Zebrafish",
        "refseq_name": "synaptotagmin-2 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005166211",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005166211",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "syt2b",
        "gene_names_refseq": "syt2b",
        "protein_names_uniprotkb": "Synaptotagmin",
        "protein_names_refseq": "synaptotagmin-2 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:559637)",
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        "publication_id_list": "",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 2,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 2,
        "predicted_c_glycosites": 0,
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        "secondary_ac_list": "A0AC58JWG8",
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        "go_molecular_function": "GO:0005509 calcium ion binding;GO:0005544 calcium-dependent phospholipid binding;GO:0000149 SNARE binding;GO:0061891 calcium ion sensor activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon;GO:0030672 synaptic vesicle membrane;GO:0070382 exocytic vesicle;GO:0042584 chromaffin granule membrane",
        "go_biological_process": "GO:0016192 vesicle-mediated transport;GO:0017158 regulation of calcium ion-dependent exocytosis;GO:2000300 regulation of synaptic vesicle exocytosis;GO:0071911 synchronous neurotransmitter secretion;GO:0099502 calcium-dependent activation of synaptic vesicle fusion",
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        "record_id": "A0A8M9QBF7-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A8M9QBG2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9QBG2",
                "type": "external"
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        ],
        "mass": 225058.0,
        "length": 1974,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC101882673",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": [
            {
                "id": "XP_021332996",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332996",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC101882673",
        "gene_names_refseq": "LOC101882673",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:101882673)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 2,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 2,
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        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003676 nucleic acid binding",
        "go_cellular_component": "",
        "go_biological_process": "GO:0015074 DNA integration",
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        "record_id": "A0A8M9QBG2-1",
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        "kg_view_protein": true
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    {
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                "id": "A0A8M9QBL6_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9QBL6",
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        ],
        "mass": 69345.0,
        "length": 615,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC101882840",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": [
            {
                "id": "XP_021336898",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021336898",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC101882840",
        "gene_names_refseq": "LOC101882840",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
        "disease": "",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021336898.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0AC58H855",
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        "go_cellular_component": "",
        "go_biological_process": "",
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        "hit_score": 0.1,
        "record_id": "A0A8M9QBL6-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A8M9QBN8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9QBN8",
                "type": "external"
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        ],
        "mass": 105932.0,
        "length": 949,
        "protein_name": "Uncharacterized protein si:zfos-932h1.3 isoform X1",
        "gene_name": "si:zfos-932h1.3",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:zfos-932h1.3 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_021330860",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021330860",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "si:zfos-932h1.3",
        "gene_names_refseq": "si:zfos-932h1.3",
        "protein_names_uniprotkb": "Uncharacterized protein si:zfos-932h1.3 isoform X1",
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        "gene_name": "jac1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "gene_name": "il16",
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        "disease": "inflammatory bowel disease (Disease Ontology:DOID:0050589); colorectal adenocarcinoma (Disease Ontology:DOID:0050861); prostate cancer (Disease Ontology:DOID:10283); asthma (Disease Ontology:DOID:2841); glioblastoma (Disease Ontology:DOID:3068); malignant astrocytoma (Disease Ontology:DOID:3069); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); periodontal disease (Disease Ontology:DOID:3388); rhinitis (Disease Ontology:DOID:4483); borna disease (Disease Ontology:DOID:5154); chronic fatigue syndrome (Disease Ontology:DOID:8544)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021333386.1. COMPLETENESS: full length., [RefSeq]; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "refseq_ac": [
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        "pathway": " (dre:563332);  (R-DRE-3214847);  (R-DRE-6804757);  (R-DRE-6804759);  (R-DRE-69541)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        ],
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        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01035969.1, SRR32588725.9126533.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505376, SAMEA3505387 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000008.1. On Jul 31, 2008 this sequence version replaced XP_691768.3., [RefSeq]",
        "predicted_glycosites": 1,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "WD repeat-containing protein 19",
        "gene_name": "wdr19",
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        "protein_names_refseq": "WD repeat-containing protein 19 isoform X1",
        "tax_id": 7955,
        "disease": "Senior-Loken syndrome (Disease Ontology:DOID:0050576); Caroli disease (Disease Ontology:DOID:0050876); ciliopathy (Disease Ontology:DOID:0060340); spermatogenic failure 72 (Disease Ontology:DOID:0070571); cranioectodermal dysplasia 4 (Disease Ontology:DOID:0080806); asphyxiating thoracic dystrophy 5 (Disease Ontology:DOID:0110089); nephronophthisis 13 (Disease Ontology:DOID:0111121); retinitis pigmentosa (Disease Ontology:DOID:10584)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; As component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in cilia function and/or assembly. Essential for functional IFT-A assembly and ciliary entry of GPCRs. Associates with the BBSome complex to mediate ciliary transport., [UniProtKB, UniProtKB]",
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        "protein_name": "Interleukin-17 receptor B",
        "gene_name": "il17rb",
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            }
        ],
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        "refseq_name": "scavenger receptor cysteine-rich domain-containing group B protein",
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        "gene_names_refseq": "LOC100331436",
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        "protein_names_refseq": "scavenger receptor cysteine-rich domain-containing group B protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        ],
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021332080.2. COMPLETENESS: full length., [RefSeq]",
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            {
                "id": "A0A8M9QEL9_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9QEL9",
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        ],
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            {
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        ],
        "gene_names_uniprotkb": "waplb",
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        "protein_names_uniprotkb": "Wings apart-like protein homolog; WAPL cohesin release factor",
        "protein_names_refseq": "wings apart-like protein homolog",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin. Involved in both sister chromatid cohesion during interphase and sister-chromatid resolution during early stages of mitosis. Couples DNA replication to sister chromatid cohesion. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair., [UniProtKB, UniProtKB]",
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    {
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        ],
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        "protein_name": "SH2 domain-containing protein 4B isoform X1",
        "gene_name": "sh2d4bb",
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        "refseq_ac": [
            {
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        ],
        "gene_names_uniprotkb": "sh2d4bb",
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        "protein_names_refseq": "SH2 domain-containing protein 4B isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021336034.2. COMPLETENESS: full length., [RefSeq]",
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        ],
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        "protein_name": "Uncharacterized protein LOC100332352; Uncharacterized protein isoform X1",
        "gene_name": "si:dkey-58f10.12",
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        "refseq_ac": [
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        "gene_names_refseq": "si:dkey-58f10.12",
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        "protein_names_refseq": "uncharacterized protein LOC100332352",
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        "function": "##Evidence-Data-START## Transcript exon combination :: EH521818.1, EH495497.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On or before Sep 4, 2020 this sequence version replaced XP_009299971.1, XP_021332240.1., [RefSeq]",
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        "protein_name": "Centromere protein V",
        "gene_name": "cenpv",
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        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0032502 developmental process",
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        "protein_names_uniprotkb": "G protein-regulated inducer of neurite outgrowth 3",
        "protein_names_refseq": "G protein-regulated inducer of neurite outgrowth 3",
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        "protein_name": "BEN domain-containing protein 6 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021336028.1. COMPLETENESS: full length., [RefSeq]",
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    {
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        "protein_name": "Uncharacterized protein zgc:171604",
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        "refseq_ac": [
            {
                "id": "XP_073804921",
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        "protein_names_uniprotkb": "Uncharacterized protein zgc:171604",
        "protein_names_refseq": "uncharacterized protein zgc:171604",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2-like",
        "gene_name": "LOC108191311",
        "organism": "Zebrafish",
        "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2-like",
        "refseq_ac": [
            {
                "id": "NP_001418276",
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        "gene_names_uniprotkb": "LOC108191311",
        "gene_names_refseq": "LOC108191311",
        "protein_names_uniprotkb": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2-like",
        "protein_names_refseq": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2-like",
        "tax_id": 7955,
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588722.45436547.1, SRR32588730.718387.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505372, SAMEA3505379 [ECO:0000348] ##Evidence-Data-END## INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from JBMGRA010000009.1., [RefSeq]",
        "predicted_glycosites": 0,
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    {
        "uniprot_canonical_ac": "A0A8M9PDM1-1",
        "uniprot_id": [
            {
                "id": "SACA6_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9PDM1",
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        ],
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        "length": 317,
        "protein_name": "Sperm acrosome membrane-associated protein 6",
        "gene_name": "spaca6",
        "organism": "Zebrafish",
        "refseq_name": "sperm acrosome membrane-associated protein 6 precursor",
        "refseq_ac": [
            {
                "id": "NP_001384707",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384707",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "spaca6; si:dkeyp-84f3.4",
        "gene_names_refseq": "si:dkeyp-84f3.4; spaca6",
        "protein_names_uniprotkb": "Sperm acrosome membrane-associated protein 6",
        "protein_names_refseq": "sperm acrosome membrane-associated protein 6 precursor; sperm acrosome membrane-associated protein 6",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:101885333)",
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        "publication_id_list": "23594743;27189481;34556579;35047514;39423812",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01020792.1, SRR32588722.5445246.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN18715719, SAMN18715720 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1., [RefSeq]; Sperm protein required for fusion of sperm with the egg membrane during fertilization (PubMed:35047514, PubMed:39423812). May regulate the expression of sperm surface protein DCST2 (PubMed:35047514)., [UniProtKB, PubMed, PubMed]",
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        "go_cellular_component": "GO:0002080 acrosomal membrane",
        "go_biological_process": "GO:0043012 regulation of fusion of sperm to egg plasma membrane;GO:0035036 sperm-egg recognition;GO:0007342 fusion of sperm to egg plasma membrane involved in single fertilization",
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        "protein_name": "Transient receptor potential cation channel subfamily M member 5",
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        "protein_names_uniprotkb": "Transient receptor potential cation channel subfamily M member 5",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_695923.3. COMPLETENESS: full length., [RefSeq]; Intracellular channel initially characterized as a non-selective Ca(2+)-permeable channel activated by NAADP (nicotinic acid adenine dinucleotide phosphate), it is also a voltage-gated highly-selective Na(+) channel activated directly by PI(3,5)P2 (phosphatidylinositol 3,5-bisphosphate) that senses pH changes and confers electrical excitability to organelles. Localizes to the early and recycling endosomes membranes where it plays a role in the uptake and processing of proteins and regulates organellar membrane excitability, membrane trafficking and pH homeostasis. Ion selectivity is not fixed but rather agonist-dependent and under defined ionic conditions, can be readily activated by both NAADP and PI(3,5)P2. Required for mTOR-dependent nutrient sensing., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0031901 early endosome membrane;GO:0055038 recycling endosome membrane;GO:0034702 monoatomic ion channel complex;GO:0036019 endolysosome",
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        ],
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        "gene_name": "si:ch211-214p13.3",
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        "refseq_name": "nectin 1a-like isoform X1",
        "refseq_ac": [
            {
                "id": "XP_693160",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693160",
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        ],
        "gene_names_uniprotkb": "si:ch211-214p13.3",
        "gene_names_refseq": "si:ch211-214p13.3",
        "protein_names_uniprotkb": "Nectin 1a-like isoform X1",
        "protein_names_refseq": "nectin 1a-like isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_693160.1. COMPLETENESS: full length., [RefSeq]",
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        "gene_name": "cabp4",
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        "protein_names_refseq": "EF-hand calcium-binding domain-containing protein 6 isoform X1",
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        "protein_names_refseq": "centrosome and spindle pole associated protein 1 isoform X1",
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        "protein_name": "Retinol dehydrogenase 12 isoform X1",
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        "tax_id": 7955,
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        "ec_number_list": [],
        "go_molecular_function": "GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds",
        "go_cellular_component": "",
        "go_biological_process": "GO:0005975 carbohydrate metabolic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
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        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A8M9QKT0_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9QKT0",
                "type": "external"
            }
        ],
        "mass": 76569.0,
        "length": 682,
        "protein_name": "Ankyrin repeat and LEM domain-containing protein 2",
        "gene_name": "LOC569920",
        "organism": "Zebrafish",
        "refseq_name": "ankyrin repeat and LEM domain-containing protein 2 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_021334900",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021334900",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC569920",
        "gene_names_refseq": "LOC569920",
        "protein_names_uniprotkb": "Ankyrin repeat and LEM domain-containing protein 2; LEM domain-containing protein 4",
        "protein_names_refseq": "ankyrin repeat and LEM domain-containing protein 2 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:569920)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in mitotic nuclear envelope reassembly by promoting dephosphorylation of BAF/BANF1 during mitotic exit. Coordinates the control of BAF/BANF1 dephosphorylation by inhibiting VRK1 kinase and promoting dephosphorylation of BAF/BANF1 by protein phosphatase 2A (PP2A), thereby facilitating nuclear envelope assembly. May regulate nuclear localization of VRK1 in non-dividing cells. It is unclear whether it acts as a real PP2A regulatory subunit or whether it is involved in recruitment of the PP2A complex. Involved in brain development., [UniProtKB, UniProtKB]",
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        "missing_score": 10000,
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        "secondary_ac_list": "A0AC58GL02;A0AC58GL06",
        "ec_number_list": [],
        "go_molecular_function": "GO:0051721 protein phosphatase 2A binding",
        "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane",
        "go_biological_process": "GO:0031468 nuclear membrane reassembly;GO:0007399 nervous system development;GO:0051301 cell division;GO:0007084 mitotic nuclear membrane reassembly",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
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        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
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    {
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            {
                "id": "A0A8M9QHF1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9QHF1",
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        ],
        "mass": 37329.0,
        "length": 323,
        "protein_name": "C-type lectin domain-containing protein",
        "gene_name": "LOC110440085",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "XP_021335186",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021335186",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC110440085",
        "gene_names_refseq": "LOC110440085",
        "protein_names_uniprotkb": "C-type lectin domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
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        "pathway": " (dre:110440085)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021335186.2. COMPLETENESS: full length., [RefSeq]",
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        "kg_view_protein": true
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    {
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            {
                "id": "A0A8M9QHJ0_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9QHJ0",
                "type": "external"
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        ],
        "mass": 41651.0,
        "length": 417,
        "protein_name": "Heterogeneous nuclear ribonucleoprotein A1a isoform X1",
        "gene_name": "hnrnpa1a",
        "organism": "Zebrafish",
        "refseq_name": "heterogeneous nuclear ribonucleoprotein A1a isoform 2",
        "refseq_ac": [
            {
                "id": "NP_001428354",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001428354",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "hnrnpa1a; zgc:66127",
        "gene_names_refseq": "hnrnpa1a; zgc:66127",
        "protein_names_uniprotkb": "Heterogeneous nuclear ribonucleoprotein A1a isoform X1",
        "protein_names_refseq": "heterogeneous nuclear ribonucleoprotein A1a isoform 2",
        "tax_id": 7955,
        "disease": "inclusion body myopathy with Paget disease of bone and frontotemporal dementia (Disease Ontology:DOID:0050881); amyotrophic lateral sclerosis type 20 (Disease Ontology:DOID:0060211); distal myopathy 3 (Disease Ontology:DOID:0111189); inclusion body myopathy with early-onset Paget disease of bone with or without frontotemporal dementia 3 (Disease Ontology:DOID:0111386); Alzheimer's disease (Disease Ontology:DOID:10652); neurodegenerative disease (Disease Ontology:DOID:1289); HTLV-1-associated myelopathy/tropical spastic paraparesis (Disease Ontology:DOID:321); lung non-small cell carcinoma (Disease Ontology:DOID:3908); hepatocellular carcinoma (Disease Ontology:DOID:684)",
        "pathway": " (dre:393467)",
        "pathway_count": 1,
        "publication_count": 7,
        "publication_id_list": "20528263;26147004;26469318;27189481;28381614;30165106;31227602",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395062.1769960.1, SRR26395039.487871.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1. On Jun 10, 2025 this sequence version replaced XP_021335236.2., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "ec_number_list": [],
        "go_molecular_function": "GO:0003730 mRNA 3'-UTR binding",
        "go_cellular_component": "GO:1990904 ribonucleoprotein complex",
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        "synthesized_glycan_count": 0,
        "hit_score": 0.8,
        "record_id": "A0A8M9QHJ0-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
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    {
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            {
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                "url": "https://www.uniprot.org/uniprot/A0A8M9QHL0",
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        ],
        "mass": 101247.0,
        "length": 906,
        "protein_name": "Uncharacterized protein si:ch211-196p9.1 isoform X1",
        "gene_name": "si:ch211-196p9.1",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:ch211-196p9.1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_021333435",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333435",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:ch211-196p9.1",
        "gene_names_refseq": "si:ch211-196p9.1",
        "protein_names_uniprotkb": "Uncharacterized protein si:ch211-196p9.1 isoform X1",
        "protein_names_refseq": "uncharacterized protein si:ch211-196p9.1 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:563968)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "kg_view_protein": true
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            {
                "id": "A0A8M9QHL3_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9QHL3",
                "type": "external"
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        ],
        "mass": 132376.0,
        "length": 1249,
        "protein_name": "Insulin receptor substrate 1-B isoform X1",
        "gene_name": "si:ch73-335l21.1",
        "organism": "Zebrafish",
        "refseq_name": "insulin receptor substrate 1-B isoform X1",
        "refseq_ac": [
            {
                "id": "XP_021333440",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333440",
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        ],
        "gene_names_uniprotkb": "si:ch73-335l21.1",
        "gene_names_refseq": "si:ch73-335l21.1",
        "protein_names_uniprotkb": "Insulin receptor substrate 1-B isoform X1",
        "protein_names_refseq": "insulin receptor substrate 1-B isoform X1",
        "tax_id": 7955,
        "disease": "intellectual disability (Disease Ontology:DOID:1059); amnestic disorder (Disease Ontology:DOID:10914); glucose metabolism disease (Disease Ontology:DOID:4194); type 2 diabetes mellitus (Disease Ontology:DOID:9352)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 2,
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        "go_molecular_function": "GO:0005158 insulin receptor binding;GO:0030159 signaling receptor complex adaptor activity;GO:0043548 phosphatidylinositol 3-kinase binding",
        "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane",
        "go_biological_process": "GO:0008286 insulin receptor signaling pathway;GO:0009967 positive regulation of signal transduction",
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        "kg_view_protein": true
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                "url": "https://www.uniprot.org/uniprot/A0A8M9QHL6",
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        ],
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        "protein_name": "Histone deacetylase 11",
        "gene_name": "hdac11",
        "organism": "Zebrafish",
        "refseq_name": "histone deacetylase 11 isoform X1",
        "refseq_ac": [
            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021335266",
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        "gene_names_uniprotkb": "hdac11; zgc:91942",
        "gene_names_refseq": "hdac11; zgc:91942",
        "protein_names_uniprotkb": "Histone deacetylase 11; 3.5.1.98",
        "protein_names_refseq": "histone deacetylase 11 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021335266.1. COMPLETENESS: full length., [RefSeq]; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "ec_number_list": [
            {
                "id": "3.5.1.98",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.98",
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            },
            {
                "id": "3.5.1.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.-",
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        "go_cellular_component": "GO:0000118 histone deacetylase complex",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0040029 epigenetic regulation of gene expression",
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    {
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            {
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        ],
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        "protein_name": "Uncharacterized protein si:dkey-19b23.8",
        "gene_name": "si:dkey-19b23.8",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:dkey-19b23.8",
        "refseq_ac": [
            {
                "id": "XP_021333450",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333450",
                "type": "external"
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        "gene_names_uniprotkb": "si:dkey-19b23.8",
        "gene_names_refseq": "si:dkey-19b23.8",
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        "protein_names_refseq": "uncharacterized protein si:dkey-19b23.8",
        "tax_id": 7955,
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        "pathway": " (dre:569132)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "go_cellular_component": "GO:0005769 early endosome",
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    {
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                "url": "https://www.uniprot.org/uniprot/A0A8M9QHY5",
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        ],
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        "protein_name": "WD repeat-containing protein 97",
        "gene_name": "wdr97",
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        "refseq_name": "WD repeat-containing protein 97",
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            {
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        "protein_names_refseq": "WD repeat-containing protein 97",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021333610.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        ],
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        "gene_name": "LOC563780",
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        ],
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        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
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        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021335461.1. COMPLETENESS: full length., [RefSeq]; DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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    },
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        ],
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        "protein_name": "Polycystin-1-like protein 2 isoform X1",
        "gene_name": "pkd1l3",
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        "refseq_ac": [
            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333660",
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            }
        ],
        "gene_names_uniprotkb": "pkd1l3",
        "gene_names_refseq": "pkd1l3",
        "protein_names_uniprotkb": "Polycystin-1-like protein 2 isoform X1",
        "protein_names_refseq": "polycystin-1-like protein 2 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021333660.1. COMPLETENESS: full length., [RefSeq]",
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        "go_molecular_function": "GO:0005262 calcium channel activity",
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        ],
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        "protein_name": "GTPase IMAP family member 8",
        "gene_name": "LOC110439949",
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        ],
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        "protein_names_refseq": "GTPase IMAP family member 8 isoform X1",
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        ],
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        "protein_name": "Solute carrier family 46 member 2",
        "gene_name": "si:ch211-262i1.4",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio                   :: 100% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0022857 transmembrane transporter activity",
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            {
                "id": "A0A8M9QIH7_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9QIH7",
                "type": "external"
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        ],
        "mass": 61593.0,
        "length": 566,
        "protein_name": "Glutathione hydrolase",
        "gene_name": "LOC103909498",
        "organism": "Zebrafish",
        "refseq_name": "glutathione hydrolase 1 proenzyme-like",
        "refseq_ac": [
            {
                "id": "XP_021333880",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333880",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "LOC103909498",
        "gene_names_refseq": "LOC103909498",
        "protein_names_uniprotkb": "Glutathione hydrolase; 2.3.2.2; 3.4.19.13; Gamma-glutamyltransferase; Gamma-glutamyltranspeptidase",
        "protein_names_refseq": "glutathione hydrolase 1 proenzyme-like",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021333880.2. COMPLETENESS: full length., [RefSeq]; Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates., [UniProtKB, UniProtKB]",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.2",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.13",
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            }
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        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0006751 glutathione catabolic process;GO:0002682 regulation of immune system process;GO:0050727 regulation of inflammatory response;GO:0031179 peptide modification",
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        ],
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        "length": 647,
        "protein_name": "Ribosomal RNA processing protein 1 homolog A",
        "gene_name": "rrp1",
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        ],
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        "protein_names_uniprotkb": "Ribosomal RNA processing protein 1 homolog A",
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        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021334455.2. COMPLETENESS: full length., [RefSeq]",
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        ],
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        "protein_name": "Zinc finger protein 414 isoform X1",
        "gene_name": "znf414",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021336381",
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        "gene_names_refseq": "si:dkey-5i22.6; wu:fc85e04; znf414",
        "protein_names_uniprotkb": "Zinc finger protein 414 isoform X1",
        "protein_names_refseq": "zinc finger protein 414 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        ],
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        "protein_name": "LOW QUALITY PROTEIN: serine protease HTRA2, mitochondrial",
        "gene_name": "htra2-7",
        "organism": "Zebrafish",
        "refseq_name": "LOW QUALITY PROTEIN: serine protease HTRA2, mitochondrial",
        "refseq_ac": [
            {
                "id": "XP_021336411",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021336411",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "htra2-7",
        "gene_names_refseq": "htra2-7",
        "protein_names_uniprotkb": "LOW QUALITY PROTEIN: serine protease HTRA2, mitochondrial",
        "protein_names_refseq": "LOW QUALITY PROTEIN: serine protease HTRA2, mitochondrial",
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        "disease": "3-methylglutaconic aciduria type 8 (Disease Ontology:DOID:0070000); prostate cancer (Disease Ontology:DOID:10283); stomach cancer (Disease Ontology:DOID:10534); Alzheimer's disease (Disease Ontology:DOID:10652); asphyxia neonatorum (Disease Ontology:DOID:11088); cryptorchidism (Disease Ontology:DOID:11383); endometrial cancer (Disease Ontology:DOID:1380); Parkinson's disease (Disease Ontology:DOID:14330); status epilepticus (Disease Ontology:DOID:1824); transient cerebral ischemia (Disease Ontology:DOID:224); motor neuron disease (Disease Ontology:DOID:231); ovarian cancer (Disease Ontology:DOID:2394); middle cerebral artery infarction (Disease Ontology:DOID:3525); colorectal cancer (Disease Ontology:DOID:9256)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts                 :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021336411.2. COMPLETENESS: full length., [RefSeq]",
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        ],
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        "protein_names_refseq": "WD repeat- and FYVE domain-containing protein 4 isoform X1",
        "tax_id": 7955,
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        ],
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        "predicted_glycosites": 0,
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        "protein_name": "Polyamine-modulated factor 1",
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        "refseq_name": "polyamine-modulated factor 1",
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            {
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        "gene_names_refseq": "im:6898523; pmf1; si:dkey-6i22.5",
        "protein_names_uniprotkb": "Polyamine-modulated factor 1",
        "protein_names_refseq": "polyamine-modulated factor 1",
        "tax_id": 7955,
        "disease": "urinary bladder cancer (Disease Ontology:DOID:11054); bladder carcinoma (Disease Ontology:DOID:4007)",
        "pathway": " (dre:564240);  (R-DRE-141430);  (R-DRE-141444);  (R-DRE-2467813);  (R-DRE-2500257);  (R-DRE-5663220)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01013276.1, BC142858.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA4476743 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On or before Aug 18, 2020 this sequence version replaced XP_021336826.1, XP_692676.2., [RefSeq]",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_684341.4. COMPLETENESS: full length., [RefSeq]",
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        "go_cellular_component": "GO:0005886 plasma membrane",
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    {
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        ],
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        "gene_name": "ftr94",
        "organism": "Zebrafish",
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            {
                "id": "XP_695364",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695364",
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        "gene_names_uniprotkb": "ftr94",
        "gene_names_refseq": "ftr94",
        "protein_names_uniprotkb": "Tripartite motif-containing protein 16",
        "protein_names_refseq": "tripartite motif-containing protein 16",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 30, 2010 this sequence version replaced XP_695364.3. COMPLETENESS: full length., [RefSeq]",
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        ],
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        "protein_name": "Pre-mRNA splicing regulator USH1G",
        "gene_name": "ush1gb",
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        "refseq_ac": [
            {
                "id": "XP_685232",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685232",
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        ],
        "gene_names_uniprotkb": "ush1gb",
        "gene_names_refseq": "ush1gb",
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        "protein_names_refseq": "pre-mRNA splicing regulator USH1G",
        "tax_id": 7955,
        "disease": "Usher syndrome type 1G (Disease Ontology:DOID:0110834)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_685232.5. COMPLETENESS: full length., [RefSeq]",
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        "length": 205,
        "protein_name": "Endothelin-like toxin domain-containing protein",
        "gene_name": "LOC567978",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_696381",
                "type": "external"
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        "gene_names_uniprotkb": "LOC567978",
        "gene_names_refseq": "LOC567978",
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        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_696381.1. COMPLETENESS: full length., [RefSeq]",
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        "go_biological_process": "GO:0045987 positive regulation of smooth muscle contraction;GO:0006874 intracellular calcium ion homeostasis;GO:0019229 regulation of vasoconstriction;GO:0003100 regulation of systemic arterial blood pressure by endothelin;GO:0014826 vein smooth muscle contraction",
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        "length": 516,
        "protein_name": "Transcription factor 19",
        "gene_name": "tcf19l",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323943",
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        "protein_names_refseq": "transcription factor 19",
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        "gene_names_refseq": "ftr79",
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        "protein_names_refseq": "uncharacterized protein ftr79 isoform X1",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697894",
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        "gene_names_uniprotkb": "fam161b",
        "gene_names_refseq": "fam161b",
        "protein_names_uniprotkb": "Protein FAM161B isoform X1",
        "protein_names_refseq": "protein FAM161B isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_697894.2. COMPLETENESS: full length., [RefSeq]",
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        "go_molecular_function": "",
        "go_cellular_component": "GO:0005856 cytoskeleton",
        "go_biological_process": "GO:0044782 cilium organization",
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            {
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        ],
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        "protein_name": "Uncharacterized protein si:ch211-250g4.3",
        "gene_name": "si:ch211-250g4.3",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:ch211-250g4.3",
        "refseq_ac": [
            {
                "id": "XP_685984",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685984",
                "type": "external"
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        ],
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        "gene_names_refseq": "si:ch211-250g4.3",
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        "protein_names_refseq": "uncharacterized protein si:ch211-250g4.3",
        "tax_id": 7955,
        "disease": "",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_685984.5. COMPLETENESS: full length., [RefSeq]",
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                "id": "A0A8N7T6X9_DANRE",
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            {
                "id": "XP_688915",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_688915",
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        ],
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        "protein_names_refseq": "tripartite motif-containing protein 16-like protein",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_688915.1. COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "Extracellular calcium-sensing receptor isoform X2",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_683668",
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        ],
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        "protein_names_uniprotkb": "Extracellular calcium-sensing receptor isoform X2",
        "protein_names_refseq": "extracellular calcium-sensing receptor isoform X2",
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        "protein_name": "Acyl-coenzyme A thioesterase 1 isoform X1",
        "gene_name": "acot21",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690536",
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        ],
        "gene_names_uniprotkb": "acot21",
        "gene_names_refseq": "acot21",
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        "protein_names_refseq": "acyl-coenzyme A thioesterase 1 isoform X1",
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        "disease": "type 2 diabetes mellitus (Disease Ontology:DOID:9352)",
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        ],
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        "gene_names_refseq": "si:dkeyp-50b9.1",
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        "protein_names_refseq": "uncharacterized protein si:dkeyp-50b9.1 isoform X1",
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            {
                "id": "XP_686062",
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                "id": "XP_687488",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687488",
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        "refseq_name": "potassium voltage-gated channel subfamily A member 10",
        "refseq_ac": [
            {
                "id": "XP_021332962",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332962",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "kcna10b; LOC567521",
        "gene_names_refseq": "LOC567521",
        "protein_names_uniprotkb": "Potassium voltage-gated channel subfamily A member 10",
        "protein_names_refseq": "potassium voltage-gated channel subfamily A member 10",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:567521)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Voltage-gated potassium ion channel that mediates K(+) permeability of excitable membranes. When opened in response to the voltage difference across the membrane, KCNA10 channel selectively allows the flow of potassium ions across the membrane down their electrochemical gradient., [UniProtKB, UniProtKB]",
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        "missing_score": 10000,
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        "ec_number_list": [
            {
                "id": "2.7.11.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1",
                "type": "external"
            },
            {
                "id": "1.5.1.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.1.2",
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            }
        ],
        "go_molecular_function": "GO:0005251 delayed rectifier potassium channel activity",
        "go_cellular_component": "GO:0016020 membrane;GO:0008076 voltage-gated potassium channel complex",
        "go_biological_process": "GO:0051260 protein homooligomerization;GO:0001508 action potential;GO:0071805 potassium ion transmembrane transport",
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        "kg_view_protein": true
    },
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            {
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                "url": "https://www.uniprot.org/uniprot/A0A8N7T841",
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        ],
        "mass": 37380.0,
        "length": 325,
        "protein_name": "P2Y purinoceptor 6",
        "gene_name": "p2ry6",
        "organism": "Zebrafish",
        "refseq_name": "P2Y purinoceptor 6",
        "refseq_ac": [
            {
                "id": "XP_694459",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_694459",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "p2ry6",
        "gene_names_refseq": "p2ry6",
        "protein_names_uniprotkb": "P2Y purinoceptor 6",
        "protein_names_refseq": "P2Y purinoceptor 6",
        "tax_id": 7955,
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        "pathway": " (dre:566099)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_694459.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0001621 G protein-coupled ADP receptor activity;GO:0045029 G protein-coupled UDP receptor activity;GO:0045030 G protein-coupled UTP receptor activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0002250 adaptive immune response;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway;GO:1905835 cellular response to pyrimidine ribonucleotide",
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        ],
        "mass": 58086.0,
        "length": 523,
        "protein_name": "Sodium-dependent lysophosphatidylcholine symporter 1",
        "gene_name": "LOC570014",
        "organism": "Zebrafish",
        "refseq_name": "sodium-dependent lysophosphatidylcholine symporter 1",
        "refseq_ac": [
            {
                "id": "XP_021330193",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021330193",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC570014",
        "gene_names_refseq": "LOC570014",
        "protein_names_uniprotkb": "Sodium-dependent lysophosphatidylcholine symporter 1",
        "protein_names_refseq": "sodium-dependent lysophosphatidylcholine symporter 1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021330193.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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    {
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        "protein_name": "Cadherin-1 isoform X1",
        "gene_name": "LOC568392",
        "organism": "Zebrafish",
        "refseq_name": "cadherin-1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_696808",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_696808",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC568392",
        "gene_names_refseq": "LOC568392",
        "protein_names_uniprotkb": "Cadherin-1 isoform X1",
        "protein_names_refseq": "cadherin-1 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_696808.3. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_biological_process": "GO:0016477 cell migration;GO:0001764 neuron migration;GO:0000902 cell morphogenesis;GO:0007043 cell-cell junction assembly;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules",
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        ],
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        "length": 291,
        "protein_name": "Uncharacterized protein si:rp71-36a1.1 isoform X1",
        "gene_name": "si:rp71-36a1.1",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:rp71-36a1.1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_700664",
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        ],
        "gene_names_uniprotkb": "si:rp71-36a1.1",
        "gene_names_refseq": "si:rp71-36a1.1",
        "protein_names_uniprotkb": "Uncharacterized protein si:rp71-36a1.1 isoform X1",
        "protein_names_refseq": "uncharacterized protein si:rp71-36a1.1 isoform X1",
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                "url": "https://www.uniprot.org/uniprot/A0A8N7T8J6",
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        "protein_name": "Armadillo repeat-containing protein 5",
        "gene_name": "armc5",
        "organism": "Zebrafish",
        "refseq_name": "armadillo repeat-containing protein 5",
        "refseq_ac": [
            {
                "id": "XP_698416",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_698416",
                "type": "external"
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        "gene_names_uniprotkb": "armc5",
        "gene_names_refseq": "armc5",
        "protein_names_uniprotkb": "Armadillo repeat-containing protein 5",
        "protein_names_refseq": "armadillo repeat-containing protein 5",
        "tax_id": 7955,
        "disease": "ACTH-independent macronodular adrenal hyperplasia 2 (Disease Ontology:DOID:0111624)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_698416.4. COMPLETENESS: full length., [RefSeq]",
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    {
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        "gene_names_refseq": "hhipl2",
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        "protein_name": "Regulator of G-protein signaling 5 isoform X2",
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        "protein_names_refseq": "regulator of G-protein signaling 5 isoform X2",
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        "protein_name": "Major facilitator superfamily domain-containing protein 8",
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        ],
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        "protein_name": "Zinc-binding protein A33 isoform X1",
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            {
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        "protein_name": "Solute carrier family 35 member D3",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_694556",
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        "secondary_ac_list": "A8E7H0",
        "ec_number_list": [],
        "go_molecular_function": "GO:0047372 monoacylglycerol lipase activity;GO:0004622 phosphatidylcholine lysophospholipase activity",
        "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane",
        "go_biological_process": "GO:0052651 monoacylglycerol catabolic process;GO:0006660 phosphatidylserine catabolic process",
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        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A8N7TD67_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8N7TD67",
                "type": "external"
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        ],
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        "length": 545,
        "protein_name": "DEP domain-containing protein 7",
        "gene_name": "depdc7b",
        "organism": "Zebrafish",
        "refseq_name": "DEP domain-containing protein 7",
        "refseq_ac": [
            {
                "id": "XP_690061",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690061",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "depdc7b",
        "gene_names_refseq": "depdc7b",
        "protein_names_uniprotkb": "DEP domain-containing protein 7",
        "protein_names_refseq": "DEP domain-containing protein 7",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:337546)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_690061.7. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_biological_process": "GO:0035556 intracellular signal transduction",
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        "kg_view_protein": true
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    {
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            {
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                "url": "https://www.uniprot.org/uniprot/A0A8N7TD91",
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        ],
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        "length": 383,
        "protein_name": "Bcl-2-like protein 12 isoform X1",
        "gene_name": "bcl2l12",
        "organism": "Zebrafish",
        "refseq_name": "bcl-2-like protein 12 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_685054",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685054",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "bcl2l12",
        "gene_names_refseq": "bcl2l12",
        "protein_names_uniprotkb": "Bcl-2-like protein 12 isoform X1",
        "protein_names_refseq": "bcl-2-like protein 12 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_685054.3. COMPLETENESS: full length., [RefSeq]",
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    {
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            {
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                "url": "https://www.uniprot.org/uniprot/A0A8N7TDD3",
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        ],
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        "length": 2021,
        "protein_name": "Uncharacterized protein igsf9b isoform X1",
        "gene_name": "igsf9b",
        "organism": "Zebrafish",
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        "refseq_ac": [
            {
                "id": "XP_686205",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_686205",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "igsf9b",
        "gene_names_refseq": "igsf9b",
        "protein_names_uniprotkb": "Uncharacterized protein igsf9b isoform X1",
        "protein_names_refseq": "uncharacterized protein igsf9b isoform X1",
        "tax_id": 7955,
        "disease": "depressive disorder (Disease Ontology:DOID:1596)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_686205.5. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "kg_view_protein": true
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    {
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            {
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                "url": "https://www.uniprot.org/uniprot/A0A8N7TDI6",
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        ],
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        "length": 400,
        "protein_name": "Fibroblast growth factor receptor homolog 1",
        "gene_name": "si:ch211-167j9.5",
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        "refseq_name": "fibroblast growth factor receptor homolog 1",
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        "protein_names_uniprotkb": "Fibroblast growth factor receptor homolog 1",
        "protein_names_refseq": "fibroblast growth factor receptor homolog 1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_693602.4. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0005524 ATP binding;GO:0019838 growth factor binding;GO:0005021 vascular endothelial growth factor receptor activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex;GO:0012505 endomembrane system",
        "go_biological_process": "GO:0001525 angiogenesis;GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0008284 positive regulation of cell population proliferation;GO:0016477 cell migration;GO:0030335 positive regulation of cell migration",
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    {
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        "uniprot_id": [
            {
                "id": "A0A8N7TDM0_DANRE",
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        ],
        "mass": 127191.0,
        "length": 1153,
        "protein_name": "Wings apart-like protein homolog",
        "gene_name": "wapla",
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            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_688605",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "wapla",
        "gene_names_refseq": "wapla",
        "protein_names_uniprotkb": "Wings apart-like protein homolog; WAPL cohesin release factor",
        "protein_names_refseq": "wings apart-like protein homolog",
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        "pathway": " (dre:553345);  (R-DRE-2467813);  (R-DRE-2468052);  (R-DRE-2470946);  (R-DRE-2500257)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_688605.5. COMPLETENESS: full length., [RefSeq]; Regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin. Involved in both sister chromatid cohesion during interphase and sister-chromatid resolution during early stages of mitosis. Couples DNA replication to sister chromatid cohesion. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair., [UniProtKB, UniProtKB]",
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        "secondary_ac_list": "F1QTA7;F1QU33",
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        "go_molecular_function": "",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005694 chromosome",
        "go_biological_process": "GO:0051301 cell division",
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    {
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                "url": "https://www.uniprot.org/uniprot/A0A8N7TDV0",
                "type": "external"
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        ],
        "mass": 96610.0,
        "length": 870,
        "protein_name": "Extracellular calcium-sensing receptor",
        "gene_name": "olfck1",
        "organism": "Zebrafish",
        "refseq_name": "extracellular calcium-sensing receptor",
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            {
                "id": "XP_696250",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_696250",
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        ],
        "gene_names_uniprotkb": "olfck1",
        "gene_names_refseq": "olfck1",
        "protein_names_uniprotkb": "Extracellular calcium-sensing receptor",
        "protein_names_refseq": "extracellular calcium-sensing receptor",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_696250.8. COMPLETENESS: full length., [RefSeq]",
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    {
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        ],
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        "length": 394,
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        "gene_name": "LOC569391",
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        "gene_names_refseq": "LOC569391",
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        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045595 regulation of cell differentiation",
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        ],
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        "gene_name": "sacs2",
        "organism": "Zebrafish",
        "refseq_name": "sacsin",
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        ],
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        "protein_name": "C1q-related factor",
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                "id": "XP_683865",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_683865",
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        ],
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        "protein_names_uniprotkb": "C1q-related factor",
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        "tax_id": 7955,
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