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RGD1564744", "gene_names_refseq": "Rplp1l1", "protein_names_uniprotkb": "Large ribosomal subunit protein P1; 60S acidic ribosomal protein P1", "protein_names_refseq": "large ribosomal subunit protein P1-like", "tax_id": 10116, "disease": "intrinsic cardiomyopathy (Disease Ontology:DOID:0060036)", "pathway": " (rno:314652)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays an important role in the elongation step of protein synthesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043021 ribonucleoprotein complex binding;GO:0030295 protein kinase activator activity;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0006417 regulation of translation;GO:0006414 translational elongation;GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0H2UHJ3-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0R4J8U1-1", "uniprot_id": [ { "id": "A0A0R4J8U1_RAT", "url": "https://www.uniprot.org/uniprot/A0A0R4J8U1", "type": "external" } ], "mass": 79945.0, "length": 708, "protein_name": "Tyrosine-protein kinase", "gene_name": "Zap70", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Zap70", "gene_names_refseq": "", "protein_names_uniprotkb": "Tyrosine-protein kinase; 2.7.10.2", "protein_names_refseq": "", "tax_id": 10116, "disease": "infantile onset multisystem autoimmune disease 2 (Disease Ontology:DOID:0061161); immunodeficiency 48 (Disease Ontology:DOID:0111943); severe combined immunodeficiency (Disease Ontology:DOID:627); rheumatoid arthritis (Disease Ontology:DOID:7148)", "pathway": " (rno:301348); (R-RNO-202430); (R-RNO-202433); (R-RNO-9013407)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.1.4.11", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.11", "type": "external" }, { "id": "2.7.10.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.4", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.32", "type": "external" }, { "id": "2.7.1.82", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.82", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.1.1.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.13", "type": "external" } ], "go_molecular_function": "GO:0001784 phosphotyrosine residue binding;GO:0004672 protein kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005911 cell-cell junction;GO:0016020 membrane", "go_biological_process": "GO:0045061 thymic T cell selection;GO:0006468 protein phosphorylation;GO:0006955 immune response;GO:0018108 peptidyl-tyrosine phosphorylation;GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0R4J8U1-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0U1RRY7-1", "uniprot_id": [ { "id": "A0A0U1RRY7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0U1RRY7", "type": "external" } ], "mass": 63128.0, "length": 590, "protein_name": "Max-binding protein MNT", "gene_name": "Mnt", "organism": "Rat", "refseq_name": "max-binding protein MNT", "refseq_ac": [ { "id": "NP_001099277", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099277", "type": "external" } ], "gene_names_uniprotkb": "Mnt", "gene_names_refseq": "Mnt", "protein_names_uniprotkb": "Max-binding protein MNT; Myc antagonist MNT; Protein ROX", "protein_names_refseq": "MNT, MAX dimerization protein; max binding protein; max-binding protein MNT", "tax_id": 10116, "disease": "Miller-Dieker lissencephaly syndrome (Disease Ontology:DOID:0060469)", "pathway": " (rno:287521)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23535568", "class_list": "", "function": "Binds DNA as a heterodimer with MAX and represses transcription. Binds to the canonical E box sequence 5'-CACGTG-3' and, with higher affinity, to 5'-CACGCG-3'., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; These data identify Mnt as a previously unrecognized negative regulator of pathological vascular remodeling., [RefSeq, PubMed]", "predicted_glycosites": 6, "predicted_n_glycosites": 0, "predicted_o_glycosites": 6, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0070443 Mad-Max complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:0090398 cellular senescence", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0U1RRY7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0U1RRZ3-1", "uniprot_id": [ { "id": "A0A0U1RRZ3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0U1RRZ3", "type": "external" } ], "mass": 88420.0, "length": 786, "protein_name": "NF-kappa-B-repressing factor", "gene_name": "Nkrf", "organism": "Rat", "refseq_name": "NF-kappa-B-repressing factor", "refseq_ac": [ { "id": "NP_001389153", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001389153", "type": "external" } ], "gene_names_uniprotkb": "Nkrf", "gene_names_refseq": "Nkrf", "protein_names_uniprotkb": "NF-kappa-B-repressing factor", "protein_names_refseq": "NF-kappa-B-repressing factor-like; NF-kappa-B-repressing factor; NF-kappaB repressing factor", "tax_id": 10116, "disease": "", "pathway": " (rno:100910054)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Enhances the ATPase activity of DHX15 by acting like a brace that tethers mobile sections of DHX15 together, stabilizing a functional conformation with high RNA affinity of DHX15. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription. May also act as a DNA-binding transcription regulator: interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001671 ATPase activator activity;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0U1RRZ3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1B0GWQ8-1", "uniprot_id": [ { "id": "A0A1B0GWQ8_RAT", "url": "https://www.uniprot.org/uniprot/A0A1B0GWQ8", "type": "external" } ], "mass": 183886.0, "length": 1733, "protein_name": "Methyl-CpG-binding domain protein 5", "gene_name": "Mbd5", "organism": "Rat", "refseq_name": "methyl-CpG-binding domain protein 5 isoform X1", "refseq_ac": [ { "id": "XP_056841390", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_056841390", "type": "external" } ], "gene_names_uniprotkb": "Mbd5", "gene_names_refseq": "Mbd5", "protein_names_uniprotkb": "Methyl-CpG-binding domain protein 5; Methyl-CpG-binding protein MBD5", "protein_names_refseq": "methyl-CpG-binding domain protein 5 isoform X1", "tax_id": 10116, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041); autosomal dominant intellectual developmental disorder (Disease Ontology:DOID:0060307); autosomal dominant intellectual developmental disorder 1 (Disease Ontology:DOID:0070031)", "pathway": " (rno:311026); (R-RNO-5689603)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Non-catalytic component of the polycomb repressive deubiquitinase (PR-DUB) complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-120' (H2AK119ub1). Important for stability of PR-DUB components and stimulating its ubiquitinase activity. As part of the PR-DUB complex, associates with chromatin enriched in histone marks H3K4me1, H3K4me3, and H3K27Ac, but not in H3K27me3. The PR-DUB complex is an epigenetic regulator of gene expression, including genes involved in cell growth and survivability. MBD5 and MBD6 containing complexes associate with distinct chromatin regions enriched in genes involved in different pathways. Heterochromatin recruitment is not mediated by DNA methylation. The PR-DUB complex is an epigenetic regulator of gene expression, including genes involved in development, cell communication, signaling, cell proliferation and cell viability., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005694 chromosome;GO:0010369 chromocenter", "go_biological_process": "GO:0060399 positive regulation of growth hormone receptor signaling pathway;GO:0007399 nervous system development;GO:0040014 regulation of multicellular organism growth;GO:0042593 glucose homeostasis;GO:0050795 regulation of behavior", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1B0GWQ8-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3Z840-1", "uniprot_id": [ { "id": "D3Z840_RAT", "url": "https://www.uniprot.org/uniprot/D3Z840", "type": "external" } ], "mass": 149536.0, "length": 1332, "protein_name": "FA complementation group I", "gene_name": "Fanci", "organism": "Rat", "refseq_name": "Fanconi anemia group I protein", "refseq_ac": [ { "id": "NP_001414599", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414599", "type": "external" } ], "gene_names_uniprotkb": "Fanci", "gene_names_refseq": "Fanci", "protein_names_uniprotkb": "FA complementation group I", "protein_names_refseq": "Fanconi anemia group I protein; Fanconi anemia, complementation group I", "tax_id": 10116, "disease": "female breast cancer (Disease Ontology:DOID:0050671); tongue squamous cell carcinoma (Disease Ontology:DOID:0050865); Fanconi anemia complementation group I (Disease Ontology:DOID:0111091); Fanconi anemia (Disease Ontology:DOID:13636)", "pathway": " (R-RNO-6783310)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0070182 DNA polymerase binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:1990391 DNA repair complex", "go_biological_process": "GO:0006281 DNA repair;GO:0031398 positive regulation of protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3Z840-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3Z8A6-1", "uniprot_id": [ { "id": "D3Z8A6_RAT", "url": "https://www.uniprot.org/uniprot/D3Z8A6", "type": "external" } ], "mass": 35025.0, "length": 312, "protein_name": "Olfactory receptor", "gene_name": "Or14j3", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Or14j3; LOC100365012", "gene_names_refseq": "", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:309578); (rno:406014)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3Z8A6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3Z8G4-1", "uniprot_id": [ { "id": "D3Z8G4_RAT", "url": "https://www.uniprot.org/uniprot/D3Z8G4", "type": "external" } ], "mass": 135457.0, "length": 1219, "protein_name": "A disintegrin and metalloproteinase with thrombospondin motifs 18", "gene_name": "Adamts18", "organism": "Rat", "refseq_name": "A disintegrin and metalloproteinase with thrombospondin motifs 18 precursor", "refseq_ac": [ { "id": "NP_001178873", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178873", "type": "external" } ], "gene_names_uniprotkb": "Adamts18", "gene_names_refseq": "Adamts18; RGD1560118", "protein_names_uniprotkb": "A disintegrin and metalloproteinase with thrombospondin motifs 18", "protein_names_refseq": "A disintegrin and metalloproteinase with thrombospondin motifs 18 precursor; A disintegrin and metalloproteinase with thrombospondin motifs 18; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18", "tax_id": 10116, "disease": "", "pathway": " (rno:361412); (R-RNO-5173214)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "38229317", "class_list": "", "function": "The progression of obstructive renal fibrosis in rats is regulated by ADAMTS18 gene methylation in the embryonic kidney through the AKT/Notch pathway., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0031012 extracellular matrix", "go_biological_process": "GO:0006508 proteolysis;GO:0030198 extracellular matrix organization;GO:0090331 negative regulation of platelet aggregation;GO:0001654 eye development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3Z8G4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3Z8M1-1", "uniprot_id": [ { "id": "D3Z8M1_RAT", "url": "https://www.uniprot.org/uniprot/D3Z8M1", "type": "external" } ], "mass": 36068.0, "length": 329, "protein_name": "Olfactory receptor", "gene_name": "Or2t44b", "organism": "Rat", "refseq_name": "olfactory receptor Olr1452", "refseq_ac": [ { "id": "NP_001000773", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000773", "type": "external" } ], "gene_names_uniprotkb": "Or2t44b", "gene_names_refseq": "Olr1452; Or2t44b", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1452; olfactory receptor Olr1452; olfactory receptor gene Olr1452", "tax_id": 10116, "disease": "", "pathway": " (rno:405048)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3Z8M1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3Z8U5-1", "uniprot_id": [ { "id": "D3Z8U5_RAT", "url": "https://www.uniprot.org/uniprot/D3Z8U5", "type": "external" } ], "mass": 114586.0, "length": 1013, "protein_name": "Metalloendopeptidase", "gene_name": "Tll1", "organism": "Rat", "refseq_name": "tolloid-like protein 1 precursor", "refseq_ac": [ { "id": "NP_001099551", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099551", "type": "external" } ], "gene_names_uniprotkb": "Tll1", "gene_names_refseq": "Tll1; 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Ifna12l; LOC120103163", "gene_names_refseq": "LOC120103163", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "interferon alpha-12-like", "tax_id": 10116, "disease": "", "pathway": " (rno:120103163)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005125 cytokine activity;GO:0005126 cytokine receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0051607 defense response to virus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3Z919-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3Z941-1", "uniprot_id": [ { "id": "D3Z941_RAT", "url": "https://www.uniprot.org/uniprot/D3Z941", "type": "external" } ], "mass": 110297.0, "length": 979, "protein_name": "Methionine--tRNA ligase, cytoplasmic", "gene_name": "Mars1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Mars1; Mars", "gene_names_refseq": "", "protein_names_uniprotkb": "Methionine--tRNA ligase, cytoplasmic; 6.1.1.10; Methionyl-tRNA synthetase", "protein_names_refseq": "", "tax_id": 10116, "disease": "nonphotosensitive trichothiodystrophy 9 (Disease Ontology:DOID:0061024); hereditary spastic paraplegia 70 (Disease Ontology:DOID:0070454); Charcot-Marie-Tooth disease axonal type 2U (Disease Ontology:DOID:0110173); pulmonary alveolar proteinosis (Disease Ontology:DOID:12120)", "pathway": " (rno:299851); (R-RNO-9856649)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Plays a role in the synthesis of ribosomal RNA in the nucleolus., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.1.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.15", "type": "external" }, { "id": "6.1.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.17", "type": "external" }, { "id": "6.1.1.10", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.10", "type": "external" }, { "id": "6.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.5", "type": "external" }, { "id": "6.1.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.12", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "6.1.1.19", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.19", "type": "external" }, { "id": "2.7.7.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.-", "type": "external" }, { "id": "6.1.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.6", "type": "external" }, { "id": "6.1.1.18", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.18", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0004825 methionine-tRNA ligase activity;GO:0000049 tRNA binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0017101 aminoacyl-tRNA synthetase multienzyme complex", "go_biological_process": "GO:0009303 rRNA transcription;GO:0071364 cellular response to epidermal growth factor stimulus;GO:0036120 cellular response to platelet-derived growth factor stimulus;GO:1901838 positive regulation of transcription of nucleolar large rRNA by RNA polymerase I;GO:0006431 methionyl-tRNA aminoacylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3Z941-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3Z984-1", "uniprot_id": [ { "id": "D3Z984_RAT", "url": "https://www.uniprot.org/uniprot/D3Z984", "type": "external" } ], "mass": 35402.0, "length": 314, "protein_name": "Olfactory receptor", "gene_name": "Or5g24", "organism": "Rat", "refseq_name": "olfactory receptor Olr447", "refseq_ac": [ { "id": "NP_001000286", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000286", "type": "external" } ], "gene_names_uniprotkb": "Or5g24", "gene_names_refseq": "Olr447; Or5g24; ratchr3-68750625-68751569_ORF", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 447; olfactory receptor Olr447; olfactory receptor gene Olr447", "tax_id": 10116, "disease": "", "pathway": " (rno:295719)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005154 epidermal growth factor receptor binding;GO:0008083 growth factor activity;GO:0048018 receptor ligand activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane", "go_biological_process": "GO:0001525 angiogenesis;GO:0007166 cell surface receptor signaling pathway;GO:0008284 positive regulation of cell population proliferation;GO:0043410 positive regulation of MAPK cascade;GO:0000165 MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3Z9P6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3Z9Y3-1", "uniprot_id": [ { "id": "D3Z9Y3_RAT", "url": "https://www.uniprot.org/uniprot/D3Z9Y3", "type": "external" } ], "mass": 59654.0, "length": 531, "protein_name": "Ceramide kinase", "gene_name": "Cerk", "organism": "Rat", "refseq_name": "ceramide kinase", "refseq_ac": [ { "id": "NP_001128333", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001128333", "type": "external" } ], "gene_names_uniprotkb": "Cerk", "gene_names_refseq": "Cerk", "protein_names_uniprotkb": "Ceramide kinase; 2.7.1.138; Acylsphingosine kinase", "protein_names_refseq": "ceramide kinase", "tax_id": 10116, "disease": "", "pathway": " (rno:300129); (R-RNO-9840309)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "14769792;21255156;29393594;32246947", "class_list": "", "function": "Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Shows a greater preference for D-erythro isomer of ceramides. Binds phosphoinositides., [UniProtKB, UniProtKB]; Ceramide kinase has a role as a mediator of calcium-dependent degranulation in mast cells., [RefSeq, PubMed]; Down-regulation of ceramide kinase via proteasome and lysosome pathways in PC12 cells by serum withdrawal: Its protection by nerve growth factor and role in exocytosis., [RefSeq, PubMed]; We have identified a differential role for ceramide kinase in mast-cell activation, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.107", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.107", "type": "external" }, { "id": "2.7.1.94", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.94", "type": "external" }, { "id": "2.7.1.138", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.138", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0001729 ceramide kinase activity;GO:0005524 ATP binding;GO:0016301 kinase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0160281 cytoplasmic side of trans-Golgi network membrane", "go_biological_process": "GO:0006672 ceramide metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "D3Z9Y3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZA43-1", "uniprot_id": [ { "id": "D3ZA43_RAT", "url": "https://www.uniprot.org/uniprot/D3ZA43", "type": "external" } ], "mass": 96307.0, "length": 835, "protein_name": "Zinc finger protein 780B", "gene_name": "Zfp780b", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Zfp780b; LOC134483039", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger protein 780B", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZA43-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZA45-1", "uniprot_id": [ { "id": "D3ZA45_RAT", "url": "https://www.uniprot.org/uniprot/D3ZA45", "type": "external" } ], "mass": 52634.0, "length": 479, "protein_name": "Autophagy-related protein 13", "gene_name": "Atg13", "organism": "Rat", "refseq_name": "autophagy-related protein 13", "refseq_ac": [ { "id": "NP_001258141", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258141", "type": "external" } ], "gene_names_uniprotkb": "Atg13", "gene_names_refseq": "Atg13; Harbi1l; Harbi1; RGD1310685", "protein_names_uniprotkb": "Autophagy-related protein 13", "protein_names_refseq": "ATG13 autophagy related 13 homolog; autophagy-related protein 13; harbinger transposase derived 1", "tax_id": 10116, "disease": "", "pathway": " (rno:362164); (R-RNO-1632852)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "22673903;33867822", "class_list": "", "function": "Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Circulating Exosomal miR-1-3p from Rats with Myocardial Infarction Plays a Protective Effect on Contrast-Induced Nephropathy via Targeting ATG13 and activating the AKT Signaling Pathway. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019887 protein kinase regulator activity;GO:0019209 kinase activator activity;GO:0019901 protein kinase binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005776 autophagosome;GO:0000407 phagophore assembly site;GO:1990316 Atg1/ULK1 kinase complex;GO:0005739 mitochondrion", "go_biological_process": "GO:0034497 protein localization to phagophore assembly site;GO:0000423 mitophagy;GO:0034727 piecemeal microautophagy of the nucleus;GO:0000045 autophagosome assembly;GO:0008285 negative regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZA45-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZAG3-1", "uniprot_id": [ { "id": "D3ZAG3_RAT", "url": "https://www.uniprot.org/uniprot/D3ZAG3", "type": "external" } ], "mass": 73600.0, "length": 646, "protein_name": "Microtubule-associated protein 9", "gene_name": "Map9", "organism": "Rat", "refseq_name": "microtubule-associated protein 9 isoform 1", "refseq_ac": [ { "id": "NP_001129188", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001129188", "type": "external" } ], "gene_names_uniprotkb": "Map9", "gene_names_refseq": "Map9; Mtap9; RGD1560368", "protein_names_uniprotkb": "Microtubule-associated protein 9", "protein_names_refseq": "microtubule-associated protein 9 isoform 1", "tax_id": 10116, "disease": "", "pathway": " (rno:310544)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding", "go_cellular_component": "GO:0000235 astral microtubule;GO:0005737 cytoplasm;GO:0030424 axon;GO:0051233 spindle midzone;GO:0015630 microtubule cytoskeleton", "go_biological_process": "GO:0046602 regulation of mitotic centrosome separation;GO:0090307 mitotic spindle assembly;GO:0000281 mitotic cytokinesis;GO:0060236 regulation of mitotic spindle organization;GO:1902412 regulation of mitotic cytokinesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZAG3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZAI1-1", "uniprot_id": [ { "id": "D3ZAI1_RAT", "url": "https://www.uniprot.org/uniprot/D3ZAI1", "type": "external" } ], "mass": 35570.0, "length": 314, "protein_name": "Olfactory receptor", "gene_name": "Or2aj4b; Or2aj4", "organism": "Rat", "refseq_name": "olfactory receptor Olr1565", "refseq_ac": [ { "id": "NP_001000908", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000908", "type": "external" } ], "gene_names_uniprotkb": "Or2aj4b; Or2aj4; Or2aj4b", "gene_names_refseq": "Olr1565; Or2aj4b", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1565; olfactory receptor Olr1565; olfactory receptor gene Olr1565", "tax_id": 10116, "disease": "", "pathway": " (rno:287973); (rno:405218)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZAI1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZAJ3-1", "uniprot_id": [ { "id": "D3ZAJ3_RAT", "url": "https://www.uniprot.org/uniprot/D3ZAJ3", "type": "external" } ], "mass": 35294.0, "length": 313, "protein_name": "Olfactory receptor", "gene_name": "Or52e5", "organism": "Rat", "refseq_name": "olfactory receptor Olr186", "refseq_ac": [ { "id": "NP_001001031", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001031", "type": "external" } ], "gene_names_uniprotkb": "Or52e5", "gene_names_refseq": "Olr186; Or52e5", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 186; olfactory receptor Olr186-like; olfactory receptor Olr186; olfactory receptor gene Olr186", "tax_id": 10116, "disease": "", "pathway": " (rno:405917)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZAJ3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZAN2-1", "uniprot_id": [ { "id": "D3ZAN2_RAT", "url": "https://www.uniprot.org/uniprot/D3ZAN2", "type": "external" } ], "mass": 143192.0, "length": 1310, "protein_name": "Cadherin-related family member 2", "gene_name": "Cdhr2", "organism": "Rat", "refseq_name": "cadherin-related family member 2 precursor", "refseq_ac": [ { "id": "NP_001414525", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414525", "type": "external" } ], "gene_names_uniprotkb": "Cdhr2", "gene_names_refseq": "Cdhr2; Pcdh24; RGD1560576", "protein_names_uniprotkb": "Cadherin-related family member 2", "protein_names_refseq": "cadherin-related family member 2 precursor; protocadherin 24", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR5 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation. May also play a role in cell-cell adhesion and contact inhibition in epithelial cells., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0050839 cell adhesion molecule binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005903 brush border;GO:0016324 apical plasma membrane;GO:0031526 brush border membrane;GO:0005902 microvillus", "go_biological_process": "GO:0007155 cell adhesion;GO:0030855 epithelial cell differentiation;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:1904970 brush border assembly;GO:0032532 regulation of microvillus length", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZAN2-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZAP7-1", "uniprot_id": [ { "id": "D3ZAP7_RAT", "url": "https://www.uniprot.org/uniprot/D3ZAP7", "type": "external" } ], "mass": 333863.0, "length": 2985, "protein_name": "ATP-dependent chromatin remodeler CHD7", "gene_name": "Chd7", "organism": "Rat", "refseq_name": "chromodomain-helicase-DNA-binding protein 7", "refseq_ac": [ { "id": "NP_001101376", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101376", "type": "external" } ], "gene_names_uniprotkb": "Chd7", "gene_names_refseq": "Chd7", "protein_names_uniprotkb": "ATP-dependent chromatin remodeler CHD7; Chromo domain-containing protein 7", "protein_names_refseq": "chromodomain-helicase-DNA-binding protein 7", "tax_id": 10116, "disease": "CHARGE syndrome (Disease Ontology:DOID:0050834); autism spectrum disorder (Disease Ontology:DOID:0060041); hypogonadotropic hypogonadism 5 with or without anosmia (Disease Ontology:DOID:0090084); congenital heart disease (Disease Ontology:DOID:1682)", "pathway": " (rno:312974); (R-RNO-9943962)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "ATP-dependent chromatin-remodeling factor, slides nucleosomes along DNA; nucleosome sliding requires ATP. Probable transcription regulator. May be involved in the in 45S precursor rRNA production., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "7.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.9.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.9.1.1", "type": "external" }, { "id": "6.1.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.12", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0000785 chromatin", "go_biological_process": "GO:0003226 right ventricular compact myocardium morphogenesis;GO:0021545 cranial nerve development;GO:0021553 olfactory nerve development;GO:0030540 female genitalia development;GO:0036302 atrioventricular canal development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZAP7-1", "record_type": "protein", "filter_code": "0000000.0000111.001000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZAP9-1", "uniprot_id": [ { "id": "D3ZAP9_RAT", "url": "https://www.uniprot.org/uniprot/D3ZAP9", "type": "external" } ], "mass": 38066.0, "length": 351, "protein_name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "gene_name": "Gpd1l", "organism": "Rat", "refseq_name": "glycerol-3-phosphate dehydrogenase 1-like protein", "refseq_ac": [ { "id": "NP_001178814", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178814", "type": "external" } ], "gene_names_uniprotkb": "Gpd1l; Gpd1l1", "gene_names_refseq": "Gpd1l1; Gpd1l; RGD1560123", "protein_names_uniprotkb": "Glycerol-3-phosphate dehydrogenase [NAD(+)]; 1.1.1.8", "protein_names_refseq": "glycerol-3-phosphate dehydrogenase 1 like 1; glycerol-3-phosphate dehydrogenase 1-like protein", "tax_id": 10116, "disease": "Brugada syndrome 2 (Disease Ontology:DOID:0110219)", "pathway": " (rno:363159); (R-RNO-1483166)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "19745168", "class_list": "", "function": "Mutations of GPD1-L may downregulate Na(v)1.5 by altering the oxidized to reduced NAD(H) balance., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.8", "type": "external" } ], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0017080 sodium channel regulator activity;GO:0044325 transmembrane transporter binding;GO:0051287 NAD binding;GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma 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"external" } ], "gene_names_uniprotkb": "Ccdc3", "gene_names_refseq": "Ccdc3; RGD1559473", "protein_names_uniprotkb": "Coiled-coil domain containing 3", "protein_names_refseq": "coiled-coil domain containing 3 precursor; coiled-coil domain-containing protein 3", "tax_id": 10116, "disease": "", "pathway": " (rno:498795)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0007165 signal transduction;GO:0008203 cholesterol metabolic process;GO:0010629 negative regulation of gene expression;GO:0045600 positive regulation of fat cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZAR0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZAU0-1", "uniprot_id": [ { "id": "D3ZAU0_RAT", "url": "https://www.uniprot.org/uniprot/D3ZAU0", "type": "external" } ], "mass": 423795.0, "length": 3925, "protein_name": "Mucin-2", "gene_name": "Muc5b", "organism": "Rat", "refseq_name": "mucin-5B precursor", "refseq_ac": [ { "id": "NP_001414085", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414085", "type": "external" } ], "gene_names_uniprotkb": "Muc5b", "gene_names_refseq": "Muc5b; RGD1561983", "protein_names_uniprotkb": "Mucin-2", "protein_names_refseq": "mucin-5B precursor; mucin-5B", "tax_id": 10116, "disease": "sinusitis (Disease Ontology:DOID:0050127); interstitial lung disease 2 (Disease Ontology:DOID:0060971); otitis media (Disease Ontology:DOID:10754); urinary bladder cancer (Disease Ontology:DOID:11054); cystic fibrosis (Disease Ontology:DOID:1485); asthma 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"id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZBS8-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZBT2-1", "uniprot_id": [ { "id": "D3ZBT2_RAT", "url": "https://www.uniprot.org/uniprot/D3ZBT2", "type": "external" } ], "mass": 11087.0, "length": 97, "protein_name": "Bublin coiled coil protein", "gene_name": "Bbln", "organism": "Rat", "refseq_name": "", "refseq_ac": [], 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(R-RNO-674695); (R-RNO-6807505); (R-RNO-73776); (R-RNO-73779); (R-RNO-75953); (R-RNO-76042)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. 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"reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0016251 RNA polymerase II general transcription initiation factor activity", "go_cellular_component": "GO:0005673 transcription factor TFIIE complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005669 transcription factor TFIID complex", "go_biological_process": "GO:0006366 transcription by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter;GO:0051123 RNA polymerase II preinitiation complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZCP9-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZCW6-1", "uniprot_id": [ { "id": "D3ZCW6_RAT", "url": "https://www.uniprot.org/uniprot/D3ZCW6", "type": "external" } ], "mass": 240518.0, "length": 2121, "protein_name": "Polycystin family receptor for egg jelly", "gene_name": "Pkdrej", "organism": "Rat", "refseq_name": "polycystin family receptor for egg jelly precursor", "refseq_ac": [ { "id": "NP_001128338", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001128338", "type": "external" } ], "gene_names_uniprotkb": "Pkdrej", "gene_names_refseq": "Pkdrej", "protein_names_uniprotkb": "Polycystin family receptor for egg jelly; PKD and REJ homolog; Polycystic kidney disease and receptor for egg jelly-related protein", "protein_names_refseq": "polycystic kidney disease (polycystin) and REJ homolog (sperm receptor for egg jelly homolog, sea urchin); polycystic kidney disease and receptor for egg jelly-related protein; polycystin (PKD) family receptor for egg jelly; polycystin family receptor for egg jelly precursor", "tax_id": 10116, 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"https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.34", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" }, { "id": "2.7.11.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.19", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.11.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.4", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.4.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.18", "type": "external" }, { "id": "3.1.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.24.-", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0035556 intracellular signal transduction", 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"reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZDM8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZDQ2-1", "uniprot_id": [ { "id": "D3ZDQ2_RAT", "url": "https://www.uniprot.org/uniprot/D3ZDQ2", "type": "external" } ], "mass": 36279.0, "length": 330, "protein_name": "NK2 homeobox 2", "gene_name": "Nkx2-2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Nkx2-2", "gene_names_refseq": "", "protein_names_uniprotkb": "NK2 homeobox 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "cancer (Disease Ontology:DOID:162); demyelinating disease (Disease Ontology:DOID:3213)", "pathway": " (rno:366214)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987 cis-regulatory region sequence-specific DNA binding;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0048708 astrocyte differentiation;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007399 nervous system development;GO:0010628 positive regulation of gene expression;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZDQ2-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZEB4-1", "uniprot_id": [ { "id": "D3ZEB4_RAT", "url": "https://www.uniprot.org/uniprot/D3ZEB4", "type": "external" } ], "mass": 35234.0, "length": 326, "protein_name": "GATA-type zinc finger protein 1", "gene_name": "Zglp1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Zglp1", "gene_names_refseq": "", "protein_names_uniprotkb": "GATA-type zinc finger protein 1; GATA-like protein 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:100360291)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcriptional regulator that plays a key role in germ cell development. Determines the oogenic fate by activating key genes for the oogenic program and meiotic prophase entry. Acts downstream of bone morphogenetic protein (BMP) by regulating expression of genes required for the oogenic programs, which are repressed by Polycomb activities in sexually uncommitted germ cells. Regulates expression of STRA8, a central downstream effector for the meiotic program. Acts independently of retinoic acid (RA). In males, not required for germ-cell sex determination, but required to allow the spermatogonia to efficiently accomplish the meiotic prophase., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007283 spermatogenesis;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0048599 oocyte development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZEB4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZEH1-1", "uniprot_id": [ { "id": "D3ZEH1_RAT", "url": "https://www.uniprot.org/uniprot/D3ZEH1", "type": "external" } ], "mass": 540457.0, "length": 4982, "protein_name": "Protocadherin Fat 4", "gene_name": "Fat4", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Fat4", "gene_names_refseq": "", "protein_names_uniprotkb": "Protocadherin Fat 4; FAT tumor suppressor homolog 4; Fat-like cadherin protein FAT-J", "protein_names_refseq": "", "tax_id": 10116, "disease": "Hennekam syndrome (Disease Ontology:DOID:0060366); Van Maldergem syndrome 2 (Disease Ontology:DOID:0080586); neurodegenerative disease (Disease Ontology:DOID:1289); carcinoma (Disease Ontology:DOID:305); obesity (Disease Ontology:DOID:9970)", "pathway": " (rno:310341)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "22673903;38843836", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 5, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005912 adherens junction;GO:0045177 apical part of cell", "go_biological_process": "GO:0072006 nephron development;GO:0043931 ossification involved in bone maturation;GO:0072137 condensed mesenchymal cell proliferation;GO:0072307 regulation of metanephric nephron tubule epithelial cell differentiation;GO:0007009 plasma membrane organization", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "D3ZEH1-1", "record_type": "protein", "filter_code": "0000000.0000111.000100.000000000000001000.0100000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZEJ0-1", "uniprot_id": [ { "id": "D3ZEJ0_RAT", "url": "https://www.uniprot.org/uniprot/D3ZEJ0", "type": "external" } ], "mass": 40303.0, "length": 365, "protein_name": "PR domain zinc finger protein 12", "gene_name": "Prdm12", "organism": "Rat", "refseq_name": "PR domain zinc finger protein 12", "refseq_ac": [ { "id": "NP_001414289", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414289", "type": "external" } ], "gene_names_uniprotkb": "Prdm12", "gene_names_refseq": "Prdm12", "protein_names_uniprotkb": "PR domain zinc finger protein 12; PR domain-containing protein 12", "protein_names_refseq": "PR domain 12; PR domain containing 12; PR domain zinc finger protein 12", "tax_id": 10116, "disease": "hereditary sensory and autonomic neuropathy type 8 (Disease Ontology:DOID:0070153)", "pathway": " (rno:688699)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcriptional regulator necessary for the development of nociceptive neurons, playing a key role in determining the nociceptive lineage from neural crest cell progenitors. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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Required for epidermal adhesion. Involved in the development of eyelids and the anterior segment of the eyeballs., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "F1T1U1", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding", "go_cellular_component": "GO:0016020 membrane;GO:0031012 extracellular matrix;GO:0005604 basement membrane", "go_biological_process": "GO:0007155 cell adhesion;GO:0007507 heart development;GO:0001822 kidney development;GO:0007160 cell-matrix adhesion;GO:0007154 cell communication", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZG74-1", "record_type": "protein", "filter_code": "0000000.0000011.001000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZGE8-1", "uniprot_id": [ { "id": "D3ZGE8_RAT", "url": "https://www.uniprot.org/uniprot/D3ZGE8", "type": "external" } ], "mass": 36060.0, "length": 313, "protein_name": "Splicing factor YJU2", "gene_name": "LOC134482366", "organism": "Rat", "refseq_name": "splicing factor YJU2-like", "refseq_ac": [ { "id": "XP_063131924", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063131924", "type": "external" } ], "gene_names_uniprotkb": "LOC134482366; YJU2", "gene_names_refseq": "LOC134482366", "protein_names_uniprotkb": "Splicing factor YJU2", "protein_names_refseq": "splicing factor YJU2-like", "tax_id": 10116, "disease": "", "pathway": " (rno:134482366)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding", "go_cellular_component": "GO:0071006 U2-type catalytic step 1 spliceosome", "go_biological_process": "GO:0000349 generation of catalytic spliceosome for first transesterification step;GO:0045292 mRNA cis splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZGE8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZGQ0-1", "uniprot_id": [ { "id": "D3ZGQ0_RAT", "url": "https://www.uniprot.org/uniprot/D3ZGQ0", "type": "external" } ], "mass": 82431.0, "length": 740, "protein_name": "Interleukin-17 receptor D", "gene_name": "Il17rd", "organism": "Rat", "refseq_name": "interleukin-17 receptor D isoform 1 precursor", "refseq_ac": [ { "id": "NP_001178866", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178866", "type": "external" } ], "gene_names_uniprotkb": "Il17rd", "gene_names_refseq": "Il17rd; 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Or5a21; ratchr1-215397764-215396805_ORF", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 332; olfactory receptor Olr332; olfactory receptor gene Olr332", "tax_id": 10116, "disease": "", "pathway": " (rno:293769)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZGU4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZGW2-1", "uniprot_id": [ { "id": "D3ZGW2_RAT", "url": "https://www.uniprot.org/uniprot/D3ZGW2", "type": "external" } ], "mass": 66080.0, "length": 628, "protein_name": "Junctophilin", "gene_name": "Ap1g2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ap1g2", "gene_names_refseq": "", "protein_names_uniprotkb": "Junctophilin", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:100362547); (R-RNO-432720)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH4 is brain-specific and appears to have an active role in certain neurons involved in motor coordination and memory., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0035615 clathrin adaptor activity", "go_cellular_component": "GO:0005790 smooth endoplasmic reticulum;GO:0005798 Golgi-associated vesicle;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0043198 dendritic shaft", "go_biological_process": "GO:0006896 Golgi to vacuole transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZGW2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZH36-1", "uniprot_id": [ { "id": "D3ZH36_RAT", "url": "https://www.uniprot.org/uniprot/D3ZH36", "type": "external" } ], "mass": 89960.0, "length": 820, "protein_name": "Extracellular leucine-rich repeat and fibronectin type III domain containing 2", "gene_name": "Elfn2", "organism": "Rat", "refseq_name": "extracellular leucine-rich repeat and fibronectin type III domain containing 2 precursor", "refseq_ac": [ { "id": "NP_001419157", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001419157", "type": "external" } ], "gene_names_uniprotkb": "Elfn2; Elfn2-ps1; LOC100910536", "gene_names_refseq": "Elfn2-ps1; Elfn2; RGD1559693", "protein_names_uniprotkb": "Extracellular leucine-rich repeat and fibronectin type III domain containing 2", "protein_names_refseq": "extracellular leucine-rich repeat and fibronectin type III containing 2; extracellular leucine-rich repeat and fibronectin type III domain containing 2 precursor; extracellular leucine-rich repeat and fibronectin type III domain containing 2, pseudogene 1; protein phosphatase 1 regulatory subunit 29-like", "tax_id": 10116, "disease": "", "pathway": " (rno:100910536)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "22673903;38843836", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004864 protein phosphatase inhibitor activity;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045202 synapse;GO:0098839 postsynaptic density membrane", "go_biological_process": "GO:0007268 chemical synaptic transmission;GO:0045184 establishment of protein localization;GO:0099560 synaptic membrane adhesion;GO:0010467 gene expression", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "D3ZH36-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0100000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZH42-1", "uniprot_id": [ { "id": "D3ZH42_RAT", "url": "https://www.uniprot.org/uniprot/D3ZH42", "type": "external" } ], "mass": 142998.0, "length": 1283, "protein_name": "RNA helicase Mov10l1", "gene_name": "Mov10l1", "organism": "Rat", "refseq_name": "RNA helicase Mov10l1", "refseq_ac": [ { "id": "NP_001414417", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414417", "type": "external" } ], "gene_names_uniprotkb": "Mov10l1", "gene_names_refseq": "Mov10l1", "protein_names_uniprotkb": "RNA helicase Mov10l1; 3.6.4.13", "protein_names_refseq": "Moloney leukemia virus 10-like 1; Mov10 RISC complex RNA helicase like 1; Mov10 like RISC complex RNA helicase 1; Mov10l1, Moloney leukemia virus 10-like 1, homolog; RNA helicase Mov10l1", "tax_id": 10116, "disease": "spermatogenic failure 73 (Disease Ontology:DOID:0070572); primary ovarian insufficiency (Disease Ontology:DOID:5426)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the primary piRNA metabolic process. Specifically binds to piRNA precursors and promotes the generation of intermediate piRNA processing fragments that are subsequently loaded to Piwi proteins. Acts via its ATP-dependent RNA helicase activity: displays 5'-3' RNA unwinding activity and probably mediates unwinding and funneling of single-stranded piRNA precursor transcripts to the endonuclease that catalyzes the first cleavage step of piRNA processing to generate piRNA intermediate fragments that are subsequently loaded to Piwi proteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "7.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.9.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.9.1.1", "type": "external" }, { "id": "6.1.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.12", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0034584 piRNA binding;GO:0003724 RNA helicase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0071546 pi-body;GO:0043186 P granule", "go_biological_process": "GO:0007283 spermatogenesis;GO:0007281 germ cell development;GO:0007140 male meiotic nuclear division;GO:0035194 regulatory ncRNA-mediated post-transcriptional gene silencing;GO:0045786 negative regulation of cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZH42-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZH49-1", "uniprot_id": [ { "id": "D3ZH49_RAT", "url": "https://www.uniprot.org/uniprot/D3ZH49", "type": "external" } ], "mass": 36021.0, "length": 316, "protein_name": "Olfactory receptor family 6 subfamily C member 68", "gene_name": "Or6c68", "organism": "Rat", "refseq_name": "olfactory receptor Olr1006", "refseq_ac": [ { "id": "NP_001000075", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000075", "type": "external" } ], "gene_names_uniprotkb": "Or6c68", "gene_names_refseq": "Olr1006; Or6c68; ratchr7-6593123-6592173_ORF", "protein_names_uniprotkb": "Olfactory receptor family 6 subfamily C member 68", "protein_names_refseq": "olfactory receptor 1006; olfactory receptor Olr1006; olfactory receptor gene Olr1006", "tax_id": 10116, "disease": "", "pathway": " (rno:288886)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZH49-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZH78-1", "uniprot_id": [ { "id": "D3ZH78_RAT", "url": "https://www.uniprot.org/uniprot/D3ZH78", "type": "external" } ], "mass": 47099.0, "length": 455, "protein_name": "G protein regulated inducer of neurite outgrowth 2", "gene_name": "Gprin2", "organism": "Rat", "refseq_name": "G protein-regulated inducer of neurite outgrowth 2", "refseq_ac": [ { "id": "NP_001386074", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386074", "type": "external" } ], "gene_names_uniprotkb": "Gprin2", "gene_names_refseq": "Gprin2; RGD1308922", "protein_names_uniprotkb": "G protein regulated inducer of neurite outgrowth 2", "protein_names_refseq": "G protein-regulated inducer of neurite outgrowth 2", "tax_id": 10116, "disease": "", "pathway": " (rno:306284)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "May be involved in neurite outgrowth., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0031175 neuron projection development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZH78-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZHG4-1", "uniprot_id": [ { "id": "D3ZHG4_RAT", "url": "https://www.uniprot.org/uniprot/D3ZHG4", "type": "external" } ], "mass": 105215.0, "length": 947, "protein_name": "Oxysterol-binding protein", "gene_name": "Osbp2", "organism": "Rat", "refseq_name": "oxysterol-binding protein 2 isoform X6", "refseq_ac": [ { "id": "XP_063129258", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063129258", "type": "external" } ], "gene_names_uniprotkb": "Osbp2", "gene_names_refseq": "Osbp2; RGD1309479", "protein_names_uniprotkb": "Oxysterol-binding protein", "protein_names_refseq": "oxysterol-binding protein 2 isoform X6", "tax_id": 10116, "disease": "cholangiocarcinoma (Disease Ontology:DOID:4947)", "pathway": " (rno:305475)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015485 cholesterol binding", "go_cellular_component": "GO:0001669 acrosomal vesicle;GO:0097440 apical dendrite;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0097038 perinuclear endoplasmic reticulum", "go_biological_process": "GO:0006869 lipid transport;GO:0007286 spermatid development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZHG4-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZHM7-1", "uniprot_id": [ { "id": "D3ZHM7_RAT", "url": "https://www.uniprot.org/uniprot/D3ZHM7", "type": "external" } ], "mass": 84785.0, "length": 761, "protein_name": "Deoxynucleotidyltransferase, terminal, interacting protein 2", "gene_name": "Dnttip2", "organism": "Rat", "refseq_name": "deoxynucleotidyltransferase terminal-interacting protein 2", "refseq_ac": [ { "id": "NP_001386671", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386671", "type": "external" } ], "gene_names_uniprotkb": "Dnttip2; LOC100910753", "gene_names_refseq": "Dnttip2; RGD1309084", "protein_names_uniprotkb": "Deoxynucleotidyltransferase, terminal, interacting protein 2", "protein_names_refseq": "deoxynucleotidyltransferase terminal-interacting protein 2-like; deoxynucleotidyltransferase terminal-interacting protein 2", "tax_id": 10116, "disease": "", "pathway": " (rno:100910753)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0032040 small-subunit processome", "go_biological_process": "GO:0006396 RNA processing;GO:0042274 ribosomal small subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZHM7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZHQ8-1", "uniprot_id": [ { "id": "D3ZHQ8_RAT", "url": "https://www.uniprot.org/uniprot/D3ZHQ8", "type": "external" } ], "mass": 64792.0, "length": 541, "protein_name": "Zinc finger (CCCH type), RNA binding motif and serine/arginine rich 2", "gene_name": "Zrsr2", "organism": "Rat", "refseq_name": "U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2", "refseq_ac": [ { "id": "NP_001414218", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414218", "type": "external" } ], "gene_names_uniprotkb": "Zrsr2", "gene_names_refseq": "RGD1559763; 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DHX29; LOC100362324", "gene_names_refseq": "Dhx29", "protein_names_uniprotkb": "ATP-dependent RNA helicase DHX29; 3.6.4.13; DEAH box protein 29", "protein_names_refseq": "ATP-dependent RNA helicase DHX29; DEAH (Asp-Glu-Ala-His) box polypeptide 29; DEAH-box helicase 29", "tax_id": 10116, "disease": "", "pathway": " (rno:100362324)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity., [UniProtKB, HAMAP, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "7.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.9.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.9.1.1", "type": "external" }, { "id": "6.1.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.12", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0043024 ribosomal small subunit binding;GO:0008494 translation activator activity", "go_cellular_component": "GO:0016282 eukaryotic 43S preinitiation complex;GO:0022627 cytosolic small ribosomal subunit;GO:0005737 cytoplasm", "go_biological_process": "GO:0001731 formation of translation preinitiation complex;GO:0042255 ribosome assembly;GO:0045948 positive regulation of translational initiation", 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Tcfap2e; Tfap2e", "protein_names_uniprotkb": "Transcription factor AP-2 epsilon", "protein_names_refseq": "transcription factor AP-2-epsilon", "tax_id": 10116, "disease": "sleep disorder (Disease Ontology:DOID:535)", "pathway": " (rno:313596); (R-RNO-8866904); (R-RNO-8866907)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0042802 identical protein binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0042127 regulation of cell population proliferation;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZJ69-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZJE0-1", "uniprot_id": [ { "id": "D3ZJE0_RAT", "url": "https://www.uniprot.org/uniprot/D3ZJE0", "type": "external" } ], "mass": 73420.0, "length": 650, "protein_name": "alpha-1,2-Mannosidase", "gene_name": "Edem1", "organism": "Rat", "refseq_name": "ER degradation-enhancing alpha-mannosidase-like protein 1", "refseq_ac": [ { "id": "NP_001292208", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292208", "type": "external" } ], "gene_names_uniprotkb": "Edem1", "gene_names_refseq": "Edem1; RGD1563633", "protein_names_uniprotkb": "alpha-1,2-Mannosidase; 3.2.1.-", "protein_names_refseq": "ER degradation enhancer, mannosidase alpha-like 1; ER degradation-enhancing alpha-mannosidase-like 1; ER degradation-enhancing alpha-mannosidase-like protein 1", "tax_id": 10116, "disease": "cystic fibrosis (Disease Ontology:DOID:1485)", "pathway": " (rno:297504)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "17360537", "class_list": "", "function": "Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It has low mannosidase activity, catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2., [UniProtKB, UniProtKB]; The endoplasmic reticulum quality control vesicular transport pathway using EDEM1 does not involve the COPII exit sites, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0051787 misfolded protein binding;GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0044322 endoplasmic reticulum quality control compartment", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0036503 ERAD pathway;GO:1904380 endoplasmic reticulum mannose trimming;GO:1904154 positive regulation of retrograde protein transport, ER to cytosol", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZJE0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZJM7-1", "uniprot_id": [ { "id": "D3ZJM7_RAT", "url": "https://www.uniprot.org/uniprot/D3ZJM7", "type": "external" } ], "mass": 92371.0, "length": 836, "protein_name": "Microcephalin", "gene_name": "Mcph1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Mcph1", "gene_names_refseq": "", "protein_names_uniprotkb": "Microcephalin", "protein_names_refseq": "", "tax_id": 10116, "disease": "oral squamous cell carcinoma (Disease Ontology:DOID:0050866); primary autosomal recessive microcephaly 1 (Disease Ontology:DOID:0070285); autosomal recessive primary microcephaly (Disease Ontology:DOID:0070296); microcephaly (Disease Ontology:DOID:10907); endometrial cancer (Disease Ontology:DOID:1380); breast cancer (Disease Ontology:DOID:1612); renal carcinoma (Disease Ontology:DOID:4451)", "pathway": " (R-RNO-2299718)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Implicated in chromosome condensation and DNA damage induced cellular responses. May play a role in neurogenesis and regulation of the size of the cerebral cortex., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding", "go_cellular_component": "GO:0005813 centrosome", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0000278 mitotic cell cycle;GO:0021987 cerebral cortex development;GO:0050727 regulation of inflammatory response;GO:0060348 bone development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZJM7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZJU0-1", "uniprot_id": [ { "id": "D3ZJU0_RAT", "url": "https://www.uniprot.org/uniprot/D3ZJU0", "type": "external" } ], "mass": 195057.0, "length": 1826, "protein_name": "AT-rich interactive domain-containing protein 2", "gene_name": "Arid2", "organism": "Rat", "refseq_name": "AT-rich interactive domain-containing protein 2", "refseq_ac": [ { "id": "NP_001419436", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001419436", "type": "external" } ], "gene_names_uniprotkb": "Arid2", "gene_names_refseq": "Arid2", "protein_names_uniprotkb": "AT-rich interactive domain-containing protein 2; BRG1-associated factor 200; Zinc finger protein with activation potential; Zipzap/p200", "protein_names_refseq": "AT rich interactive domain 2 (Arid-rfx like); AT-rich interactive domain-containing protein 2", "tax_id": 10116, "disease": "oral squamous cell carcinoma (Disease Ontology:DOID:0050866); Coffin-Siris syndrome 6 (Disease Ontology:DOID:0080297); alcohol use disorder (Disease Ontology:DOID:1574); hepatocellular carcinoma (Disease Ontology:DOID:684); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (rno:366980)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). May be involved in targeting the complex to different genes. May be involved in regulating transcriptional activation of cardiac genes., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0016514 SWI/SNF complex;GO:0035060 brahma complex", "go_biological_process": "GO:0072359 circulatory system development;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0008285 negative regulation of cell population proliferation;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZJU0-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZKC9-1", "uniprot_id": [ { "id": "D3ZKC9_RAT", "url": "https://www.uniprot.org/uniprot/D3ZKC9", "type": "external" } ], "mass": 215857.0, "length": 1931, "protein_name": "Vir like m6A methyltransferase associated", "gene_name": "Virma", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Virma; RGD1559904", "gene_names_refseq": "", "protein_names_uniprotkb": "Vir like m6A methyltransferase associated", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:313061)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0036396 RNA N6-methyladenosine methyltransferase complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0016607 nuclear speck", "go_biological_process": "GO:0006397 mRNA processing;GO:0008380 RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZKC9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZKE0-1", "uniprot_id": [ { "id": "D3ZKE0_RAT", "url": "https://www.uniprot.org/uniprot/D3ZKE0", "type": "external" } ], "mass": 140017.0, "length": 1228, "protein_name": "N-acetylglucosamine-1-phosphotransferase subunits alpha/beta", "gene_name": "Gnptab", "organism": "Rat", "refseq_name": "N-acetylglucosamine-1-phosphotransferase subunits alpha/beta", "refseq_ac": [ { "id": "NP_001414087", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414087", "type": "external" } ], "gene_names_uniprotkb": "Gnptab", "gene_names_refseq": "Gnptab; RGD1564821", "protein_names_uniprotkb": "N-acetylglucosamine-1-phosphotransferase subunits alpha/beta; 2.7.8.17; GlcNAc-1-phosphotransferase subunits alpha/beta; Stealth protein GNPTAB; UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta", "protein_names_refseq": "N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits; N-acetylglucosamine-1-phosphotransferase subunits alpha/beta", "tax_id": 10116, "disease": "mucolipidosis II alpha/beta (Disease Ontology:DOID:0080070); mucolipidosis III alpha/beta (Disease Ontology:DOID:0080071); mucolipidosis (Disease Ontology:DOID:0080488); congenital heart disease (Disease Ontology:DOID:1682)", "pathway": " (rno:362865)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the formation of mannose 6-phosphate (M6P) markers on high mannose type oligosaccharides in the Golgi apparatus. 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RGD1560943", "protein_names_uniprotkb": "AT-rich interactive domain-containing protein 3; ARID domain-containing protein", "protein_names_refseq": "AT rich interactive domain 3C (BRIGHT-like); AT-rich interactive domain-containing protein 3C", "tax_id": 10116, "disease": "", "pathway": " (rno:502946)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcription factor involved in monocyte-to-macrophage differentiation. Forms a complex with NPM1 to translocate to the nucleus, acting as a transcription factor that promotes the expression of the genes involved in macrophage differentiation, such as STAT3, STAT1 and JUNB., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 1, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0045121 membrane raft", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0030225 macrophage differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZQB1-1", "record_type": "protein", "filter_code": "0000000.1000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZQB3-1", "uniprot_id": [ { "id": "D3ZQB3_RAT", "url": "https://www.uniprot.org/uniprot/D3ZQB3", "type": "external" } ], "mass": 35277.0, "length": 311, "protein_name": "Olfactory receptor", "gene_name": "Or5w19", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Or5w19", "gene_names_refseq": "", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZQB3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZQD3-1", "uniprot_id": [ { "id": "OGDHL_RAT", "url": "https://www.uniprot.org/uniprot/D3ZQD3", "type": "external" } ], "mass": 114637.0, "length": 1010, "protein_name": "2-oxoglutarate dehydrogenase-like, mitochondrial", "gene_name": "Ogdhl", "organism": "Rat", "refseq_name": "2-oxoglutarate dehydrogenase-like, mitochondrial", "refseq_ac": [ { "id": "NP_001382038", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382038", "type": "external" } ], "gene_names_uniprotkb": "Ogdhl", "gene_names_refseq": "Ogdhl", "protein_names_uniprotkb": "2-oxoglutarate dehydrogenase-like, mitochondrial; 1.2.4.2; 2-oxoglutarate dehydrogenase complex component E1-like; Alpha-ketoglutarate dehydrogenase-like; OGDC-E1-like", "protein_names_refseq": "2-oxoglutarate dehydrogenase complex component E1-like; 2-oxoglutarate dehydrogenase-like, mitochondrial; OGDC-E1-like; alpha-ketoglutarate dehydrogenase-like; oxoglutarate dehydrogenase-like", "tax_id": 10116, "disease": "Yoon-Bellen neurodevelopmental syndrome (Disease Ontology:DOID:0070468); oxoglutarate dehydrogenase deficiency (Disease Ontology:DOID:0081326); dilated cardiomyopathy (Disease Ontology:DOID:12930)", "pathway": " (rno:290566)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15972265;18783430", "class_list": "", "function": "2-oxoglutarate dehydrogenase (E1-like) component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDHC) which mediates the decarboxylation of alpha-ketoglutarate in the tricarboxylic acid cycle (PubMed:18783430). The OGDHC complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) while reducing NAD(+) to NADH (PubMed:18783430). The OGDHC complex is mainly active in the mitochondrion (PubMed:18783430). Involved in the inhibition of cell proliferation and in apoptosis (By similarity)., [UniProtKB, UniProtKB, PubMed, UniProtKB, UniProtKB]; In contrast to the heart complex, where only the known OGDH was determined, the band corresponding to the brain OGDH component was found to also include the novel 2-oxoglutarate dehydrogenase-like (OGDHL) protein., [RefSeq, PubMed]; Oxoglutarate dehydrogenase and mitochondrial nitric-oxide synthase require calcium under hypoxic conditions, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.2.4.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.2", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0030976 thiamine pyrophosphate binding;GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0045252 oxoglutarate dehydrogenase complex", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0006103 2-oxoglutarate metabolic process;GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZQD3-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZQE8-1", "uniprot_id": [ { "id": "D3ZQE8_RAT", "url": "https://www.uniprot.org/uniprot/D3ZQE8", "type": "external" } ], "mass": 137458.0, "length": 1209, "protein_name": "Exportin-5", "gene_name": "Xpo5", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Xpo5", "gene_names_refseq": "", "protein_names_uniprotkb": "Exportin-5; Ran-binding protein 21", "protein_names_refseq": "", "tax_id": 10116, "disease": "breast cancer (Disease Ontology:DOID:1612); transitional cell carcinoma (Disease Ontology:DOID:2671); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung small cell carcinoma (Disease Ontology:DOID:5409); primary ovarian insufficiency (Disease Ontology:DOID:5426); hepatocellular carcinoma (Disease Ontology:DOID:684); colorectal cancer (Disease Ontology:DOID:9256); multiple myeloma (Disease Ontology:DOID:9538)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Mediates the nuclear export of micro-RNA precursors, which form short hairpins. Also mediates the nuclear export of synthetic short hairpin RNAs used for RNA interference. In some circumstances can also mediate the nuclear export of deacylated and aminoacylated tRNAs. Specifically recognizes dsRNAs that lack a 5'-overhang in a sequence-independent manner, have only a short 3'-overhang, and that have a double-stranded length of at least 15 base-pairs. Binding is dependent on Ran-GTP., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:1905172 RISC complex binding;GO:0003729 mRNA binding;GO:0000049 tRNA binding;GO:0031267 small GTPase binding;GO:0070883 pre-miRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016442 RISC complex", "go_biological_process": "GO:0006611 protein export from nucleus;GO:0035281 pre-miRNA export from nucleus;GO:0006405 RNA export from nucleus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZQE8-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZQG3-1", "uniprot_id": [ { "id": "D3ZQG3_RAT", "url": "https://www.uniprot.org/uniprot/D3ZQG3", "type": "external" } ], "mass": 41899.0, "length": 388, "protein_name": "Rhomboid domain-containing protein 2", "gene_name": "Rhbdd2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Rhbdd2", "gene_names_refseq": "", "protein_names_uniprotkb": "Rhomboid domain-containing protein 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZQG3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZQI7-1", "uniprot_id": [ { "id": "D3ZQI7_RAT", "url": "https://www.uniprot.org/uniprot/D3ZQI7", "type": "external" } ], "mass": 86234.0, "length": 782, "protein_name": "Zinc finger and BTB domain containing 47", "gene_name": "Zbtb47", "organism": "Rat", "refseq_name": "zinc finger and BTB domain containing 47 isoform 2", "refseq_ac": [ { "id": "NP_001417482", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417482", "type": "external" } ], "gene_names_uniprotkb": "Zbtb47", "gene_names_refseq": "RGD1562434; Zbtb47; Zfp651", "protein_names_uniprotkb": "Zinc finger and BTB domain containing 47", "protein_names_refseq": "zinc finger and BTB domain containing 47 isoform 2; zinc finger and BTB domain-containing protein 47; zinc finger protein 651", "tax_id": 10116, "disease": "", "pathway": " (rno:316087)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZQI7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZQM4-1", "uniprot_id": [ { "id": "D3ZQM4_RAT", "url": "https://www.uniprot.org/uniprot/D3ZQM4", "type": "external" } ], "mass": 35608.0, "length": 312, "protein_name": "Olfactory receptor", "gene_name": "Or52e51", "organism": "Rat", "refseq_name": "olfactory receptor Olr86", "refseq_ac": [ { "id": "NP_001000747", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000747", "type": "external" } ], "gene_names_uniprotkb": "Or52e51", "gene_names_refseq": "Olr86; Or52e51", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 86; olfactory receptor Olr86; olfactory receptor gene Olr86", "tax_id": 10116, "disease": "", "pathway": " (rno:405014)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZQM4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZQW1-1", "uniprot_id": [ { "id": "D3ZQW1_RAT", "url": "https://www.uniprot.org/uniprot/D3ZQW1", "type": "external" } ], "mass": 157213.0, "length": 1410, "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "Blm", "organism": "Rat", "refseq_name": "recQ-like DNA helicase BLM isoform X5", "refseq_ac": [ { "id": "XP_063118710", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063118710", "type": "external" } ], "gene_names_uniprotkb": "Blm", "gene_names_refseq": "Blm", "protein_names_uniprotkb": "RecQ-like DNA helicase BLM; 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Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. 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"publication_count": 1, "publication_id_list": "29393594", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZYE4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZYJ2-1", "uniprot_id": [ { "id": "D3ZYJ2_RAT", "url": "https://www.uniprot.org/uniprot/D3ZYJ2", "type": "external" } ], "mass": 14251.0, "length": 127, "protein_name": "SLC51 subunit beta", "gene_name": "Slc51b", "organism": "Rat", "refseq_name": "organic solute transporter subunit beta", "refseq_ac": [ { "id": "NP_001386190", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386190", "type": "external" } ], "gene_names_uniprotkb": "Slc51b", "gene_names_refseq": "Ostbeta; Ostb; RGD1565748; Slc51b", "protein_names_uniprotkb": "SLC51 subunit beta", "protein_names_refseq": "organic solute transporter beta; organic solute transporter subunit beta; solute carrier family 51 member beta; solute carrier family 51 subunit beta; solute carrier family 51, beta subunit", "tax_id": 10116, "disease": "", "pathway": " (rno:300790); (R-RNO-159418)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0046982 protein heterodimerization activity;GO:0015125 bile acid transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0016323 basolateral plasma membrane;GO:0032991 protein-containing complex", "go_biological_process": "GO:0015721 bile acid and bile salt transport;GO:0031647 regulation of protein stability;GO:0090314 positive regulation of protein targeting to membrane;GO:0070863 positive regulation of protein exit from endoplasmic reticulum;GO:0010560 positive regulation of glycoprotein biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZYJ2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZYP9-1", "uniprot_id": [ { "id": "D3ZYP9_RAT", "url": "https://www.uniprot.org/uniprot/D3ZYP9", "type": "external" } ], "mass": 119203.0, "length": 1093, "protein_name": "NLR family, CARD domain containing 3", "gene_name": "Nlrc3", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Nlrc3; Nlrc3-ps1", "gene_names_refseq": "", "protein_names_uniprotkb": "NLR family, CARD domain containing 3", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:287070)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16641100", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding;GO:0140678 molecular function inhibitor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm;GO:0061702 canonical inflammasome complex", "go_biological_process": "GO:0006954 inflammatory response;GO:0032496 response to lipopolysaccharide;GO:0045087 innate immune response;GO:0032691 negative regulation of interleukin-1 beta production;GO:0032715 negative regulation of interleukin-6 production", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZYP9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZZ09-1", "uniprot_id": [ { "id": "D3ZZ09_RAT", "url": "https://www.uniprot.org/uniprot/D3ZZ09", "type": "external" } ], "mass": 36158.0, "length": 327, "protein_name": "Vestigial-like family member 3", "gene_name": "Vgll3", "organism": "Rat", "refseq_name": "transcription cofactor vestigial-like protein 3 isoform 1", "refseq_ac": [ { "id": "NP_001414722", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414722", "type": "external" } ], "gene_names_uniprotkb": "Vgll3", "gene_names_refseq": "RGD1560030; Vgll3", "protein_names_uniprotkb": "Vestigial-like family member 3", "protein_names_refseq": "transcription cofactor vestigial-like protein 3 isoform 1; transcription cofactor vestigial-like protein 3; vestigial like 3", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32814879", "class_list": "", "function": "CircRNA-vgll3 promotes osteogenic differentiation of adipose-derived mesenchymal stem cells via modulating miRNA-dependent integrin alpha5 expression., [RefSeq, PubMed]; May act as a specific coactivator for the mammalian TEFs., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZZ09-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZZ61-1", "uniprot_id": [ { "id": "D3ZZ61_RAT", "url": "https://www.uniprot.org/uniprot/D3ZZ61", "type": "external" } ], "mass": 78547.0, "length": 734, "protein_name": "Centrosomal protein of 68 kDa", "gene_name": "Cep68", "organism": "Rat", "refseq_name": "centrosomal protein of 68 kDa", "refseq_ac": [ { "id": "NP_001414236", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414236", "type": "external" } ], "gene_names_uniprotkb": "Cep68", "gene_names_refseq": "Cep68; RGD1309101", "protein_names_uniprotkb": "Centrosomal protein of 68 kDa", "protein_names_refseq": "centrosomal protein 68kDa; centrosomal protein of 68 kDa", "tax_id": 10116, "disease": "", "pathway": " (rno:289822)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "22673903;29393594", "class_list": "", "function": "Involved in maintenance of centrosome cohesion, probably as part of a linker structure which prevents centrosome splitting. Required for localization of CDK5RAP2 to the centrosome during interphase. Contributes to CROCC/rootletin filament formation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0019904 protein domain specific binding", "go_cellular_component": "GO:0005813 centrosome;GO:0034451 centriolar satellite", "go_biological_process": "GO:0007098 centrosome cycle;GO:0010457 centriole-centriole cohesion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZZ61-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZZK3-1", "uniprot_id": [ { "id": "D3ZZK3_RAT", "url": "https://www.uniprot.org/uniprot/D3ZZK3", "type": "external" } ], "mass": 109838.0, "length": 986, "protein_name": "receptor protein-tyrosine kinase", "gene_name": "Epha4", "organism": "Rat", "refseq_name": "ephrin type-A receptor 4 precursor", "refseq_ac": [ { "id": "NP_001155883", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001155883", "type": "external" } ], "gene_names_uniprotkb": "Epha4", "gene_names_refseq": "Epha4; RGD1560587", "protein_names_uniprotkb": "receptor protein-tyrosine kinase; 2.7.10.1", "protein_names_refseq": "ephrin type-A receptor 4 precursor; ephrin type-A receptor 4", "tax_id": 10116, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); toxic encephalopathy (Disease Ontology:DOID:3602)", "pathway": " (rno:316539); (R-RNO-2682334); (R-RNO-3928663); (R-RNO-3928665)", "pathway_count": 4, "publication_count": 6, "publication_id_list": "31469726;33555537;33974931;36416239;37064501;38843836", "class_list": "", "function": "Effects of lncRNA HOXA11-AS on Sevoflurane-Induced Neuronal Apoptosis and Inflammatory Responses by Regulating miR-98-5p/EphA4. Publication Status: Online-Only, [RefSeq, PubMed]; EphA4 is highly expressed in the atria of heart and its deletion leads to atrial hypertrophy and electrocardiographic abnormalities in rats., [RefSeq, PubMed]; EphA4/ephrinA3 reverse signaling mediated downregulation of glutamate transporter GLAST in Muller cells in an experimental glaucoma model., [RefSeq, PubMed]; N the present study, we demonstrated that EphA4 receptor potentiated the activity of outwardly rectifying chloride channel in rat hippocampal neurons after ischemia-reperfusion, [RefSeq, PubMed]; Nogo-A-Delta20/EphA4 interaction antagonizes apoptosis of neural stem cells by integrating p38 and JNK MAPK signaling., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.10.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.4", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.32", "type": "external" }, { "id": "2.7.1.82", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.82", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0046875 ephrin receptor binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity;GO:0016301 kinase activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005737 cytoplasm;GO:0005741 mitochondrial outer membrane;GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0050770 regulation of axonogenesis;GO:0060384 innervation;GO:0097485 neuron projection guidance;GO:0007155 cell adhesion;GO:0007162 negative regulation of cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "D3ZZK3-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZZT7-1", "uniprot_id": [ { "id": "D3ZZT7_RAT", "url": "https://www.uniprot.org/uniprot/D3ZZT7", "type": "external" } ], "mass": 71057.0, "length": 625, "protein_name": "Protein phosphatase 2C-like domain containing 1", "gene_name": "Pp2d1", "organism": "Rat", "refseq_name": "protein phosphatase 2C-like domain-containing protein 1", "refseq_ac": [ { "id": "NP_001128039", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001128039", "type": "external" } ], "gene_names_uniprotkb": "Pp2d1", "gene_names_refseq": "Pp2d1; RGD1564811", "protein_names_uniprotkb": "Protein phosphatase 2C-like domain containing 1", "protein_names_refseq": "PP2C-like domain-containing protein C3orf48 homolog; protein phosphatase 2C-like domain-containing protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:316157)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0007165 signal transduction;GO:0043409 negative regulation of MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZZT7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZZW8-1", "uniprot_id": [ { "id": "D3ZZW8_RAT", "url": "https://www.uniprot.org/uniprot/D3ZZW8", "type": "external" } ], "mass": 113500.0, "length": 988, "protein_name": "Aminopeptidase", "gene_name": "Lvrn", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Lvrn; Aqpep", "gene_names_refseq": "", "protein_names_uniprotkb": "Aminopeptidase; 3.4.11.-", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Metalloprotease which may be important for placentation by regulating biological activity of key peptides at the embryo-maternal interface. Involved in coat pigmentation patterns. During skin development, may be required to establish the periodicity of tabby markings, initiating a pre-pattern at or before hair follicle development., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008237 metallopeptidase activity;GO:0008270 zinc ion binding;GO:0004177 aminopeptidase activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZZW8-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A0C0-1", "uniprot_id": [ { "id": "D4A0C0_RAT", "url": "https://www.uniprot.org/uniprot/D4A0C0", "type": "external" } ], "mass": 34853.0, "length": 315, "protein_name": "Olfactory receptor", "gene_name": "Or3a1f", "organism": "Rat", "refseq_name": "olfactory receptor Olr1511", "refseq_ac": [ { "id": "NP_001000034", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000034", "type": "external" } ], "gene_names_uniprotkb": "Or3a1f", "gene_names_refseq": "Olr1511; Or3a1f; ratchr10-61433167-61434114_ORF", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1511; olfactory receptor Olr1511; olfactory receptor gene Olr1511", "tax_id": 10116, "disease": "", "pathway": " (rno:287509)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. 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Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules., [UniProtKB, UniProtKB]; Gene expressions of ELOVL6 and SPC24 were upregulated, and SERPINA7 was downregulated in the livers of rats with ventromedial hypothalamic lesions., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0031262 Ndc80 complex;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0000776 kinetochore;GO:0000940 outer kinetochore", "go_biological_process": "GO:0007059 chromosome segregation;GO:0008608 attachment of spindle microtubules to kinetochore;GO:0051301 cell division", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A1C5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A1G8-1", "uniprot_id": [ { "id": "D4A1G8_RAT", "url": "https://www.uniprot.org/uniprot/D4A1G8", "type": "external" } ], "mass": 171695.0, "length": 1575, "protein_name": "Centrosomal protein 170B", "gene_name": "Cep170b", "organism": "Rat", "refseq_name": "centrosomal protein of 170 kDa protein B", "refseq_ac": [ { "id": "NP_001414196", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414196", "type": "external" } ], "gene_names_uniprotkb": "Cep170b", "gene_names_refseq": "Cep170b", "protein_names_uniprotkb": "Centrosomal protein 170B", "protein_names_refseq": "centrosomal protein of 170 kDa protein B", "tax_id": 10116, "disease": "", "pathway": " (rno:500726)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "16641100;22673903;38843836", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "D4A1G8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0100000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A1G9-1", "uniprot_id": [ { "id": "D4A1G9_RAT", "url": "https://www.uniprot.org/uniprot/D4A1G9", "type": "external" } ], "mass": 35112.0, "length": 312, "protein_name": "Olfactory receptor", "gene_name": "Or5w15", "organism": "Rat", "refseq_name": "olfactory receptor Olr584", "refseq_ac": [ { "id": "NP_001000661", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000661", "type": "external" } ], "gene_names_uniprotkb": "Or5w15", "gene_names_refseq": "Olr584; 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A1G9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A1I9-1", "uniprot_id": [ { "id": "D4A1I9_RAT", "url": "https://www.uniprot.org/uniprot/D4A1I9", "type": "external" } ], "mass": 46163.0, "length": 407, "protein_name": "Peptidylprolyl isomerase like 6", "gene_name": "Ppil6", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ppil6", "gene_names_refseq": "", "protein_names_uniprotkb": "Peptidylprolyl isomerase like 6", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:685567)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides., [UniProtKB, UniProtKB, UniProtKB]; Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A1I9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A242-1", "uniprot_id": [ { "id": "D4A242_RAT", "url": "https://www.uniprot.org/uniprot/D4A242", "type": "external" } ], "mass": 27468.0, "length": 252, "protein_name": "Insulin-induced gene protein", "gene_name": "LOC120102490", "organism": "Rat", "refseq_name": "insulin-induced gene 1 protein-like", "refseq_ac": [ { "id": "XP_063143009", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063143009", "type": "external" } ], "gene_names_uniprotkb": "LOC120102490", "gene_names_refseq": "LOC120102490", "protein_names_uniprotkb": "Insulin-induced gene protein", "protein_names_refseq": "insulin-induced gene 1 protein-like", "tax_id": 10116, "disease": "", "pathway": " (rno:120102490)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Mediates feedback control of cholesterol synthesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008289 lipid binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0032937 SREBP-SCAP-Insig complex", "go_biological_process": "GO:0032869 cellular response to insulin stimulus;GO:0006695 cholesterol biosynthetic process;GO:0032933 SREBP signaling pathway;GO:0036316 SREBP-SCAP complex retention in endoplasmic reticulum", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A242-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A252-1", "uniprot_id": [ { "id": "D4A252_RAT", "url": "https://www.uniprot.org/uniprot/D4A252", "type": "external" } ], "mass": 35484.0, "length": 319, "protein_name": "Olfactory receptor", "gene_name": "Or13f5", "organism": "Rat", "refseq_name": "olfactory receptor family 13 subfamily F member 5", "refseq_ac": [ { "id": "NP_001412355", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001412355", "type": "external" } ], "gene_names_uniprotkb": "Or13f5; LOC500460", "gene_names_refseq": "Or13f5", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 13F1-like; olfactory receptor family 13 subfamily F member 5", "tax_id": 10116, "disease": "", "pathway": " (rno:500460)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A252-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A254-1", "uniprot_id": [ { "id": "D4A254_RAT", "url": "https://www.uniprot.org/uniprot/D4A254", "type": "external" } ], "mass": 150415.0, "length": 1359, "protein_name": "PH domain leucine-rich repeat-containing protein phosphatase 2", "gene_name": "Phlpp2", "organism": "Rat", "refseq_name": "PH domain leucine-rich repeat-containing protein phosphatase 2", "refseq_ac": [ { "id": "NP_001102601", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102601", "type": "external" } ], "gene_names_uniprotkb": "Phlpp2", "gene_names_refseq": "Phlpp2; Phlppl; RGD1562857", "protein_names_uniprotkb": "PH domain leucine-rich repeat-containing protein phosphatase 2; 3.1.3.16; PH domain leucine-rich repeat-containing protein phosphatase-like", "protein_names_refseq": "PH domain leucine-rich repeat-containing protein phosphatase 2", "tax_id": 10116, "disease": "", "pathway": " (rno:498949)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "19450723;22673903;24675471;29628444", "class_list": "", "function": "Cellular PHLPP2 levels may aggravate oxidative toxicity by suppressing Nrf2/ARE transcriptional regulation via Akt(Se473)/GSK3beta/Fyn kinase axis. Publication Status: Online-Only, [RefSeq, PubMed]; Increased Akt activity was associated with inhibition of PHLPP2 activity by adenylyl cyclase type 6., [RefSeq, PubMed]; Loss of Phlpp2 expression is associated with cardiac hypertrophy., [RefSeq, PubMed]; Protein phosphatase involved in regulation of Akt and PKC signaling. Mediates dephosphorylation in the C-terminal domain hydrophobic motif of members of the AGC Ser/Thr protein kinase family; specifically acts on 'Ser-473' of AKT1, 'Ser-660' of PRKCB isoform beta-II and 'Ser-657' of PRKCA. Akt regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of 'Ser-473' of Akt triggers apoptosis and decreases cell proliferation. Also controls the phosphorylation of AKT3. Dephosphorylates STK4 on 'Thr-387' leading to STK4 activation and apoptosis. Dephosphorylates RPS6KB1 and is involved in regulation of cap-dependent translation. Inhibits cancer cell proliferation and may act as a tumor suppressor. Dephosphorylation of PRKCA and PRKCB leads to their destabilization and degradation. Dephosphorylates RAF1 inhibiting its kinase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, 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"external" }, { "id": "3.1.3.74", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.74", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005929 cilium;GO:0045171 intercellular bridge", "go_biological_process": "GO:0021766 hippocampus development;GO:0006470 protein dephosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "D4A254-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A275-1", "uniprot_id": [ { "id": "D4A275_RAT", "url": "https://www.uniprot.org/uniprot/D4A275", "type": "external" } ], "mass": 51353.0, "length": 444, "protein_name": "UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase", "gene_name": "Gxylt2", "organism": "Rat", "refseq_name": "glucoside xylosyltransferase 2 isoform X1", "refseq_ac": [ { "id": "XP_001066466", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001066466", "type": "external" } ], "gene_names_uniprotkb": "Gxylt2; LOC100365223", "gene_names_refseq": "Gxylt2", "protein_names_uniprotkb": "UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase; 2.4.2.42", "protein_names_refseq": "glucoside xylosyltransferase 2 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:688618)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 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"external" } ], "go_molecular_function": "GO:0035252 UDP-xylosyltransferase activity;GO:0140563 UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0016266 protein O-linked glycosylation via N-acetyl-galactosamine;GO:0180059 protein O-linked glycosylation via glucose", "synthesized_glycan_count": 7, "hit_score": 0.1, "record_id": "D4A275-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A287-1", "uniprot_id": [ { "id": "D4A287_RAT", "url": "https://www.uniprot.org/uniprot/D4A287", "type": "external" } ], "mass": 34973.0, "length": 352, "protein_name": "Class E basic helix-loop-helix protein 22", "gene_name": "Bhlhe22", "organism": "Rat", "refseq_name": "class E basic helix-loop-helix protein 22", "refseq_ac": [ { "id": "NP_001102410", "url": 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"go_biological_process": "GO:0060042 retina morphogenesis in camera-type eye;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription;GO:0030182 neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A287-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A327-1", "uniprot_id": [ { "id": "D4A327_RAT", "url": "https://www.uniprot.org/uniprot/D4A327", "type": "external" } ], "mass": 92826.0, "length": 807, "protein_name": "Zinc finger protein 780B, pseudogene 1", "gene_name": "Zfp780b-ps1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Zfp780b-ps1", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger protein 780B, pseudogene 1", "protein_names_refseq": "", "tax_id": 10116, 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"https://www.uniprot.org/uniprot/D4A355", "type": "external" } ], "mass": 96363.0, "length": 867, "protein_name": "Serine/threonine-protein kinase greatwall", "gene_name": "Mastl", "organism": "Rat", "refseq_name": "serine/threonine-protein kinase greatwall isoform X1", "refseq_ac": [ { "id": "XP_006254402", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006254402", "type": "external" } ], "gene_names_uniprotkb": "Mastl", "gene_names_refseq": "Mastl", "protein_names_uniprotkb": "Serine/threonine-protein kinase greatwall; 2.7.11.1; Microtubule-associated serine/threonine-protein kinase-like", "protein_names_refseq": "serine/threonine-protein kinase greatwall isoform X1", "tax_id": 10116, "disease": "thrombocytopenia (Disease Ontology:DOID:1588)", "pathway": " (R-RNO-2465910)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, 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"secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.34", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" }, { "id": "2.7.11.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.19", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.11.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.4", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.4.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.18", "type": "external" }, { "id": "3.1.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.24.-", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0044325 transmembrane transporter binding;GO:0016301 kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005813 centrosome;GO:0015630 microtubule cytoskeleton;GO:0032154 cleavage furrow", "go_biological_process": "GO:0007147 female meiosis II;GO:0035556 intracellular signal transduction;GO:0000086 G2/M transition of mitotic cell cycle;GO:0007346 regulation of mitotic cell cycle;GO:1904668 positive regulation of ubiquitin protein ligase activity", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A355-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A3A9-1", "uniprot_id": [ { "id": "D4A3A9_RAT", "url": "https://www.uniprot.org/uniprot/D4A3A9", "type": "external" } ], "mass": 76098.0, "length": 674, "protein_name": "Polypeptide N-acetylgalactosaminyltransferase", "gene_name": "Galnt15", "organism": "Rat", "refseq_name": "polypeptide N-acetylgalactosaminyltransferase-like protein 2", "refseq_ac": [ { "id": "NP_001420166", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001420166", "type": "external" } ], "gene_names_uniprotkb": "Galnt15", "gene_names_refseq": "Galnt15; Galntl2", "protein_names_uniprotkb": "Polypeptide N-acetylgalactosaminyltransferase; 2.4.1.-; Protein-UDP acetylgalactosaminyltransferase", "protein_names_refseq": "UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2; polypeptide N-acetylgalactosaminyltransferase-like protein 2", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-913709)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Although it displays a much weaker activity toward all substrates tested compared to GALNT2, it is able to transfer up to seven GalNAc residues to the Muc5AC peptide, suggesting that it can fill vicinal Thr/Ser residues in cooperation with other GALNT proteins. Prefers Muc1a as substrate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.-", "type": "external" }, { "id": "2.4.1.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.41", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0030246 carbohydrate binding;GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0030133 transport vesicle", "go_biological_process": "GO:0006493 protein O-linked glycosylation", "synthesized_glycan_count": 7434, "hit_score": 0.1, "record_id": "D4A3A9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A3E3-1", "uniprot_id": [ { "id": "D4A3E3_RAT", "url": "https://www.uniprot.org/uniprot/D4A3E3", "type": "external" } ], "mass": 243395.0, "length": 2291, "protein_name": "AT-rich interaction domain 1A", "gene_name": "Arid1a", "organism": "Rat", "refseq_name": "AT-rich interactive domain-containing protein 1A isoform 1", "refseq_ac": [ { "id": "NP_001388207", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001388207", "type": "external" } ], "gene_names_uniprotkb": "Arid1a", "gene_names_refseq": "Arid1a", "protein_names_uniprotkb": "AT-rich interaction domain 1A", "protein_names_refseq": "AT rich interactive domain 1A (SWI-like); AT rich interactive domain 1A (Swi1 like); AT-rich interactive domain-containing protein 1A isoform 1; AT-rich interactive domain-containing protein 1A", "tax_id": 10116, "disease": "ovarian clear cell carcinoma (Disease Ontology:DOID:0050934); Coffin-Siris syndrome 1 (Disease Ontology:DOID:0070042); Coffin-Siris syndrome 2 (Disease Ontology:DOID:0070044); stomach cancer (Disease Ontology:DOID:10534); pre-eclampsia (Disease Ontology:DOID:10591); alcohol use disorder (Disease Ontology:DOID:1574); breast cancer (Disease Ontology:DOID:1612); cancer (Disease Ontology:DOID:162); Coffin-Siris syndrome (Disease Ontology:DOID:1925); colon cancer (Disease Ontology:DOID:219); endometrial adenocarcinoma (Disease Ontology:DOID:2870); gastric adenocarcinoma (Disease Ontology:DOID:3717); lung non-small cell carcinoma (Disease Ontology:DOID:3908); esophagus adenocarcinoma (Disease Ontology:DOID:4914); Klatskin's tumor (Disease Ontology:DOID:4927); intrahepatic cholangiocarcinoma (Disease Ontology:DOID:4928); hepatocellular carcinoma (Disease Ontology:DOID:684); neuroblastoma (Disease Ontology:DOID:769); colorectal cancer (Disease Ontology:DOID:9256); nasopharynx carcinoma (Disease Ontology:DOID:9261)", "pathway": " (rno:297867); (R-RNO-3214858); (R-RNO-8939243); (R-RNO-9933937); (R-RNO-9933946); (R-RNO-9934037)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 20, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003713 transcription coactivator activity;GO:0016922 nuclear receptor binding;GO:0140658 ATP-dependent chromatin remodeler activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0016514 SWI/SNF complex;GO:0071564 npBAF complex;GO:0071565 nBAF complex;GO:0000785 chromatin", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006338 chromatin remodeling;GO:0030900 forebrain development;GO:0045893 positive regulation of DNA-templated transcription;GO:0001843 neural tube closure", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A3E3-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A3H3-1", "uniprot_id": [ { "id": "D4A3H3_RAT", "url": "https://www.uniprot.org/uniprot/D4A3H3", "type": "external" } ], "mass": 31642.0, "length": 288, "protein_name": "Cellular repressor of E1A-stimulated genes 2", "gene_name": "Creg2", "organism": "Rat", "refseq_name": "protein CREG2 isoform X1", "refseq_ac": [ { "id": "XP_038940473", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038940473", "type": "external" } ], "gene_names_uniprotkb": "Creg2", "gene_names_refseq": "Creg2", "protein_names_uniprotkb": "Cellular repressor of E1A-stimulated genes 2", "protein_names_refseq": "protein CREG2 isoform X1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A3H3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A3I0-1", "uniprot_id": [ { "id": "D4A3I0_RAT", "url": "https://www.uniprot.org/uniprot/D4A3I0", "type": "external" } ], "mass": 84106.0, "length": 734, "protein_name": "Ubiquitin thioesterase ZRANB1", "gene_name": "Zranb1", "organism": "Rat", "refseq_name": "ubiquitin thioesterase ZRANB1 isoform X1", "refseq_ac": [ { "id": "XP_006230507", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006230507", "type": "external" } ], "gene_names_uniprotkb": "Zranb1; LOC100360606", "gene_names_refseq": "Zranb1", "protein_names_uniprotkb": "Ubiquitin thioesterase ZRANB1; 3.4.19.12; Zinc finger Ran-binding domain-containing protein 1", "protein_names_refseq": "ubiquitin thioesterase ZRANB1 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:100360606); (R-RNO-195253); (R-RNO-5689896)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Ubiquitin thioesterase, which specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'-linked diubiquitin. Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Acts as a regulator of autophagy by mediating deubiquitination of PIK3C3/VPS34, thereby promoting autophagosome maturation. Plays a role in the regulation of cell morphology and cytoskeletal organization. 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"external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004706 JUN kinase kinase kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A454-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A4A0-1", "uniprot_id": [ { "id": "D4A4A0_RAT", "url": "https://www.uniprot.org/uniprot/D4A4A0", "type": "external" } ], "mass": 35931.0, "length": 322, "protein_name": "Olfactory receptor", "gene_name": "Or14j6", "organism": "Rat", "refseq_name": "olfactory receptor Olr1692", "refseq_ac": [ { "id": "NP_001000888", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000888", "type": "external" } ], "gene_names_uniprotkb": "Or14j6", "gene_names_refseq": "Olr1692; Or14j6", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1692; olfactory receptor Olr1692; olfactory receptor gene Olr1692", "tax_id": 10116, "disease": "", "pathway": " (rno:405189)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. 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"https://www.rhea-db.org/rhea/?query=ec:1.14.11.-", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0003779 actin binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0042393 histone binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005819 spindle;GO:0005829 cytosol;GO:0005874 microtubule", "go_biological_process": "GO:0060382 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"external" } ], "gene_names_uniprotkb": "Zfp366; LOC100360041", "gene_names_refseq": "Zfp366; Znf366", "protein_names_uniprotkb": "Zinc finger protein 366; Dendritic cell-specific transcript protein", "protein_names_refseq": "zinc finger protein 366", "tax_id": 10116, "disease": "DiGeorge syndrome (Disease Ontology:DOID:11198)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Has transcriptional repression activity. Acts as a corepressor of ESR1; the function seems to involve CTBP1 and histone deacetylases., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0003714 transcription corepressor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0030331 nuclear estrogen receptor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0043627 response to estrogen;GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A715-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A755-1", "uniprot_id": [ { "id": "D4A755_RAT", "url": "https://www.uniprot.org/uniprot/D4A755", "type": "external" } ], "mass": 35366.0, "length": 312, "protein_name": "Olfactory receptor", "gene_name": "Or4k48b", "organism": "Rat", "refseq_name": "olfactory receptor Olr775", "refseq_ac": [ { "id": "NP_001000374", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000374", "type": "external" } ], "gene_names_uniprotkb": "Or4k48b", "gene_names_refseq": "Olr775; Or4k48b", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 775; olfactory receptor Olr775; olfactory receptor gene Olr775", "tax_id": 10116, "disease": "", "pathway": " (rno:296028)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. 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[provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A8F8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A8H5-1", "uniprot_id": [ { "id": "D4A8H5_RAT", "url": "https://www.uniprot.org/uniprot/D4A8H5", "type": "external" } ], "mass": 45944.0, "length": 413, "protein_name": "Protein phosphatase 4, regulatory subunit 2", "gene_name": "Ppp4r2", "organism": "Rat", "refseq_name": "serine/threonine-protein phosphatase 4 regulatory subunit 2", "refseq_ac": [ { "id": "NP_001100083", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100083", "type": "external" } ], "gene_names_uniprotkb": "Ppp4r2", "gene_names_refseq": "Ppp4r2", "protein_names_uniprotkb": "Protein phosphatase 4, regulatory subunit 2", "protein_names_refseq": "serine/threonine-protein phosphatase 4 regulatory subunit 2", "tax_id": 10116, "disease": "", "pathway": " (rno:297486); (R-RNO-5693607)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "22559936;22673903", "class_list": "", "function": "PPP4R2 is required for differentiation of neuronal cells., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0019888 protein phosphatase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0000785 chromatin;GO:0030289 protein phosphatase 4 complex", "go_biological_process": "GO:0002244 hematopoietic progenitor cell differentiation;GO:0010569 regulation of double-strand break repair via homologous recombination;GO:2000779 regulation of double-strand break repair", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D4A8H5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A8J5-1", "uniprot_id": [ { "id": "D4A8J5_RAT", "url": "https://www.uniprot.org/uniprot/D4A8J5", "type": "external" } ], "mass": 89843.0, "length": 780, "protein_name": "Zinc finger protein 420-like", "gene_name": "Zfp790", "organism": "Rat", "refseq_name": "zinc finger protein 790", "refseq_ac": [ { "id": "NP_001396208", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001396208", "type": "external" } ], "gene_names_uniprotkb": "Zfp790", "gene_names_refseq": "Zfp790", "protein_names_uniprotkb": "Zinc finger protein 420-like", "protein_names_refseq": "zinc finger protein 420; zinc finger protein 790", "tax_id": 10116, "disease": "", "pathway": " (rno:102547413); (R-RNO-212436)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A8J5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A932-1", "uniprot_id": [ { "id": "D4A932_RAT", "url": "https://www.uniprot.org/uniprot/D4A932", "type": "external" } ], "mass": 114192.0, "length": 1031, "protein_name": "Pleckstrin homology domain-containing family M member 2", "gene_name": "Plekhm2", "organism": "Rat", "refseq_name": "pleckstrin homology domain-containing family M member 2", "refseq_ac": [ { "id": "NP_001178696", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178696", "type": "external" } ], "gene_names_uniprotkb": "Plekhm2", "gene_names_refseq": "Plekhm2", "protein_names_uniprotkb": "Pleckstrin homology domain-containing family M member 2", "protein_names_refseq": "pleckstrin homology domain containing, family M (with RUN domain) member 2; pleckstrin homology domain-containing family M member 2", "tax_id": 10116, "disease": "", "pathway": " (rno:313667)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in lysosomes movement and localization at the cell periphery acting as an effector of ARL8B. Required for ARL8B to exert its effects on lysosome location, recruits kinesin-1 to lysosomes and hence direct their movement toward microtubule plus ends. Binding to ARL8B provides a link from lysosomal membranes to plus-end-directed motility. Critical factor involved in NK cell-mediated cytotoxicity. Drives the polarization of cytolytic granules and microtubule-organizing centers (MTOCs) toward the immune synapse between effector NK lymphocytes and target cells. Required for maintenance of the Golgi apparatus organization. May play a role in membrane tubulation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019894 kinesin binding", "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0010008 endosome membrane", "go_biological_process": "GO:0032880 regulation of protein localization;GO:0007030 Golgi organization;GO:0032418 lysosome localization;GO:0042267 natural killer cell mediated cytotoxicity", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A932-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A986-1", "uniprot_id": [ { "id": "D4A986_RAT", "url": "https://www.uniprot.org/uniprot/D4A986", "type": "external" } ], "mass": 43510.0, "length": 412, "protein_name": "Methyl-CpG binding domain protein 2", "gene_name": "Mbd2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Mbd2", "gene_names_refseq": "", "protein_names_uniprotkb": "Methyl-CpG binding domain protein 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "transient cerebral ischemia (Disease Ontology:DOID:224); schizophrenia (Disease Ontology:DOID:5419); rheumatoid arthritis (Disease Ontology:DOID:7148); choline deficiency disease (Disease Ontology:DOID:8456); type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": " (R-RNO-427413); (R-RNO-73728); (R-RNO-9937850); (R-RNO-9940951)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0003729 mRNA binding;GO:0019904 protein domain specific binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0000785 chromatin;GO:0000118 histone deacetylase complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0042127 regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A986-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A9B0-1", "uniprot_id": [ { "id": "D4A9B0_RAT", "url": "https://www.uniprot.org/uniprot/D4A9B0", "type": "external" } ], "mass": 110459.0, "length": 983, "protein_name": "S1 RNA-binding domain-containing protein 1", "gene_name": "Srbd1", "organism": "Rat", "refseq_name": "S1 RNA-binding domain-containing protein 1 isoform X1", "refseq_ac": [ { "id": "XP_006239770", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006239770", "type": "external" } ], "gene_names_uniprotkb": "Srbd1", "gene_names_refseq": "RGD1562788; Srbd1", "protein_names_uniprotkb": "S1 RNA-binding domain-containing protein 1", "protein_names_refseq": "S1 RNA-binding domain-containing protein 1 isoform X1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "DNA- and histone-binding protein that localizes to the central axes of mitotic chromosomes. Promotes chromosome segregation by facilitating TOP2A recruitment to mitotic chromosomes, thereby preventing anaphase failure. During prophase, safeguards the decatenation process to avoid the formation of difficult-to-resolve DNA structures, preventing chromosome missegregation. Also contributes to the regulation of nucleus pulposus cell senescence., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0003735 structural constituent of ribosome;GO:0003676 nucleic acid binding", "go_cellular_component": "", "go_biological_process": "GO:0006412 translation;GO:0006139 nucleobase-containing compound metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A9B0-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A9N5-1", "uniprot_id": [ { "id": "D4A9N5_RAT", "url": "https://www.uniprot.org/uniprot/D4A9N5", "type": "external" } ], "mass": 71920.0, "length": 643, "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "Trim25", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Trim25", "gene_names_refseq": "", "protein_names_uniprotkb": "E3 ubiquitin/ISG15 ligase TRIM25; 2.3.2.27; 6.3.2.n3; Estrogen-responsive finger protein; RING-type E3 ubiquitin transferase TRIM25; RING-type E3 ubiquitin transferase; Tripartite motif-containing protein 25; Ubiquitin/ISG15-conjugating enzyme TRIM25; Zinc finger protein 147", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-1169408); (R-RNO-5656169); (R-RNO-9833482); (R-RNO-9909505)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.7.7.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "6.3.2.n3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.2.n3", "type": "external" }, { "id": "3.1.4.11", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.11", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity;GO:0016874 ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0046596 regulation of viral entry into host cell;GO:0044790 suppression of viral release by host;GO:0006979 response to oxidative stress;GO:0045087 innate immune response;GO:1990830 cellular response to leukemia inhibitory factor", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A9N5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A9W0-1", "uniprot_id": [ { "id": "D4A9W0_RAT", "url": "https://www.uniprot.org/uniprot/D4A9W0", "type": "external" } ], "mass": 40141.0, "length": 356, "protein_name": "Absent in melanoma 2", "gene_name": "Aim2", "organism": "Rat", "refseq_name": "interferon-inducible protein AIM2", "refseq_ac": [ { "id": "NP_001414422", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414422", "type": "external" } ], "gene_names_uniprotkb": "Aim2", "gene_names_refseq": "Aim2", "protein_names_uniprotkb": "Absent in melanoma 2", "protein_names_refseq": "interferon-inducible protein AIM2", "tax_id": 10116, "disease": "", "pathway": " (rno:304987); 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Publication Status: Online-Only, [RefSeq, PubMed]; Long non-coding RNA MEG3 promotes cerebral ischemia-reperfusion injury through increasing pyroptosis by targeting miR-485/AIM2 axis., [RefSeq, PubMed]; Role of AIM2 Gene Knockdown Mechanism in Diabetic Cardiomyopathy: an In Vivo and Ex Vivo Study., [RefSeq, PubMed]; The importance of HIN-200 proteins in disease now is beginning to be understood as they appear to be involved in autoimmunity and may act as tumor suppressor proteins. 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"0000000.0000001.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AD99-1", "uniprot_id": [ { "id": "D4AD99_RAT", "url": "https://www.uniprot.org/uniprot/D4AD99", "type": "external" } ], "mass": 85669.0, "length": 779, "protein_name": "Cytoplasmic polyadenylation element binding protein 3", "gene_name": "Cpeb3", "organism": "Rat", "refseq_name": "cytoplasmic polyadenylation element-binding protein 3 isoform X1", "refseq_ac": [ { "id": "XP_017445833", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017445833", "type": "external" } ], "gene_names_uniprotkb": "Cpeb3", "gene_names_refseq": "Cpeb3; RGD1564670", "protein_names_uniprotkb": "Cytoplasmic polyadenylation element binding protein 3", "protein_names_refseq": "cytoplasmic polyadenylation element-binding protein 3 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:309510)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": 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"", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000900 mRNA regulatory element binding translation repressor activity;GO:0003723 RNA binding;GO:0008135 translation factor activity, RNA binding;GO:0043022 ribosome binding;GO:0003730 mRNA 3'-UTR binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0030425 dendrite;GO:0045202 synapse", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:1900273 positive regulation of long-term synaptic potentiation;GO:0048167 regulation of synaptic plasticity;GO:0017148 negative regulation of translation;GO:0045727 positive regulation of translation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4AD99-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ADI3-1", "uniprot_id": [ { "id": "D4ADI3_RAT", "url": "https://www.uniprot.org/uniprot/D4ADI3", "type": "external" } ], "mass": 38055.0, "length": 340, "protein_name": "Krueppel-like factor 17", "gene_name": "Klf17", "organism": "Rat", "refseq_name": "Krueppel-like factor 17 isoform 1", "refseq_ac": [ { "id": "NP_001418086", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001418086", "type": "external" } ], "gene_names_uniprotkb": "Klf17", "gene_names_refseq": "Klf17; Zfp393", "protein_names_uniprotkb": "Krueppel-like factor 17; Zinc finger protein 393", "protein_names_refseq": "Krueppel-like factor 17 isoform 1; Krueppel-like factor 17; Kruppel-like factor 17; zinc finger protein 393", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003700 DNA-binding transcription factor activity;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0007276 gamete generation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4ADI3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ADK2-1", "uniprot_id": [ { "id": "D4ADK2_RAT", "url": "https://www.uniprot.org/uniprot/D4ADK2", "type": "external" } ], "mass": 37211.0, "length": 333, "protein_name": "Olfactory receptor", "gene_name": "Or10a3", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Or10a3", "gene_names_refseq": "", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "", "tax_id": 10116, "disease": "polycystic liver disease 1 (Disease Ontology:DOID:0060980); polycystic kidney disease (Disease Ontology:DOID:0080322); chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia (Disease Ontology:DOID:0112106); hypertension (Disease Ontology:DOID:10763); Parkinson's disease (Disease Ontology:DOID:14330); cholangiocarcinoma (Disease Ontology:DOID:4947); cervix uteri carcinoma in situ (Disease Ontology:DOID:8991); obesity (Disease Ontology:DOID:9970)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4ADK2-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ADQ2-1", "uniprot_id": [ { "id": "D4ADQ2_RAT", "url": "https://www.uniprot.org/uniprot/D4ADQ2", "type": "external" } ], "mass": 25128.0, "length": 222, "protein_name": "Mitochondrial cardiolipin hydrolase", "gene_name": "Pld6", "organism": "Rat", "refseq_name": "mitochondrial cardiolipin hydrolase isoform 1", "refseq_ac": [ { "id": "NP_001385510", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385510", "type": "external" } ], "gene_names_uniprotkb": "Pld6", "gene_names_refseq": "Pld6; RGD1311987", "protein_names_uniprotkb": "Mitochondrial cardiolipin hydrolase; Choline phosphatase 6; Mitochondrial phospholipase; Phosphatidylcholine-hydrolyzing phospholipase D6; Phospholipase D6; Protein zucchini homolog", "protein_names_refseq": "mitochondrial cardiolipin hydrolase isoform 1; mitochondrial cardiolipin hydrolase", "tax_id": 10116, "disease": "", "pathway": " (rno:287366); (R-RNO-1483166)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004630 phospholipase D activity;GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0016891 RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism;GO:0035755 cardiolipin hydrolase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0016042 lipid catabolic process;GO:0034587 piRNA processing;GO:0051321 meiotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4ADQ2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ADT3-1", "uniprot_id": [ { "id": "D4ADT3_RAT", "url": "https://www.uniprot.org/uniprot/D4ADT3", "type": "external" } ], "mass": 133720.0, "length": 1198, "protein_name": "Wings apart-like protein homolog", "gene_name": "Wapl", "organism": "Rat", "refseq_name": "wings apart-like protein homolog", "refseq_ac": [ { "id": "NP_001414208", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414208", "type": "external" } ], "gene_names_uniprotkb": "Wapl", "gene_names_refseq": "RGD1308960; Wapal; Wapl", "protein_names_uniprotkb": "Wings apart-like protein homolog; WAPL cohesin release factor", "protein_names_refseq": "wings apart-like homolog; wings apart-like protein homolog", "tax_id": 10116, "disease": "", "pathway": " (rno:290577); (R-RNO-2467813); (R-RNO-2468052); (R-RNO-2470946); (R-RNO-2500257)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin. Involved in both sister chromatid cohesion during interphase and sister-chromatid resolution during early stages of mitosis. Couples DNA replication to sister chromatid cohesion. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0140083 ATP-dependent protein-DNA unloader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0000776 kinetochore;GO:0000785 chromatin", "go_biological_process": "GO:0045875 negative regulation of sister chromatid cohesion;GO:0051307 meiotic chromosome separation;GO:0000278 mitotic cell cycle;GO:0008608 attachment of spindle microtubules to kinetochore;GO:0051301 cell division", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4ADT3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AE85-1", "uniprot_id": [ { "id": "D4AE85_RAT", "url": "https://www.uniprot.org/uniprot/D4AE85", "type": "external" } ], "mass": 42152.0, "length": 380, "protein_name": "Vasohibin 1", "gene_name": "Vash1", "organism": "Rat", "refseq_name": "tubulinyl-Tyr carboxypeptidase 1", "refseq_ac": [ { "id": "NP_001414164", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414164", "type": "external" } ], "gene_names_uniprotkb": "Vash1", "gene_names_refseq": "RGD1564082; Vash1", "protein_names_uniprotkb": "Vasohibin 1", "protein_names_refseq": "tubulinyl-Tyr carboxypeptidase 1", "tax_id": 10116, "disease": "portal hypertension (Disease Ontology:DOID:10762); liver cirrhosis (Disease Ontology:DOID:5082)", "pathway": " (rno:503052)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "16707096;20659423;39018366", "class_list": "", "function": "These results bring evidence that endogenous VASH-1 isoforms p36 and p42 are key actors of physiological and pathological muscle angio-adaptation., [RefSeq, PubMed]; Vasohibin has an activity to prevent neointimal formation by inhibiting adventitial angiogenesis [vasohibin], [RefSeq, PubMed]; Vasohibin inhibition improves myocardial relaxation in a rat model of heart failure with preserved ejection fraction., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0004181 metallocarboxypeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0045177 apical part of cell", "go_biological_process": "GO:1901491 negative regulation of lymphangiogenesis;GO:0001525 angiogenesis;GO:0006508 proteolysis;GO:0009611 response to wounding;GO:0001937 negative regulation of endothelial cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "D4AE85-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AEE6-1", "uniprot_id": [ { "id": "D4AEE6_RAT", "url": "https://www.uniprot.org/uniprot/D4AEE6", "type": "external" } ], "mass": 44964.0, "length": 401, "protein_name": "Kinase", "gene_name": "Ip6k3", "organism": "Rat", "refseq_name": "inositol hexakisphosphate kinase 3 isoform 1", "refseq_ac": [ { "id": "NP_001419302", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001419302", "type": "external" } ], "gene_names_uniprotkb": "Ip6k3", "gene_names_refseq": "Ihpk3; Ip6k3", "protein_names_uniprotkb": "Kinase; 2.7.-.-", "protein_names_refseq": "inositol hexakisphosphate kinase 3 isoform 1; inositol hexaphosphate kinase 3", "tax_id": 10116, "disease": "", "pathway": " (rno:688862); (R-RNO-1855167)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.-.-", "type": "external" }, { "id": "2.7.4.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.21", "type": "external" } ], "go_molecular_function": "GO:0000828 inositol hexakisphosphate kinase activity;GO:0000831 inositol hexakisphosphate 6-kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006468 protein phosphorylation;GO:0040011 locomotion;GO:0046488 phosphatidylinositol metabolic process;GO:0046854 phosphatidylinositol phosphate biosynthetic process;GO:0032958 inositol phosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4AEE6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AEG3-1", "uniprot_id": [ { "id": "D4AEG3_RAT", "url": "https://www.uniprot.org/uniprot/D4AEG3", "type": "external" } ], "mass": 57260.0, "length": 492, "protein_name": "Peptidyl-prolyl cis-trans isomerase", "gene_name": "Ppil4", "organism": "Rat", "refseq_name": "peptidyl-prolyl cis-trans isomerase-like 4", "refseq_ac": [ { "id": "NP_001381983", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001381983", "type": "external" } ], "gene_names_uniprotkb": "Ppil4", "gene_names_refseq": "Ppil4", "protein_names_uniprotkb": "Peptidyl-prolyl cis-trans isomerase; 5.2.1.8; PPIase", "protein_names_refseq": "peptidyl-prolyl cis-trans isomerase-like 4; peptidylprolyl isomerase (cyclophilin)-like 4", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-72163)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" }, { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005681 spliceosomal complex;GO:0071006 U2-type catalytic step 1 spliceosome", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4AEG3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AEJ0-1", "uniprot_id": [ { "id": "D4AEJ0_RAT", "url": "https://www.uniprot.org/uniprot/D4AEJ0", "type": "external" } ], "mass": 44273.0, "length": 384, "protein_name": "Nucleosome assembly protein 1 like 6", "gene_name": "Nap1l6", "organism": "Rat", "refseq_name": "nucleosome assembly protein 1-like 1", "refseq_ac": [ { "id": "XP_038936256", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038936256", "type": "external" } ], "gene_names_uniprotkb": "Nap1l6; 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7.6.2.2; ABCB5 P-gp; p-glycoprotein ABCB5", "protein_names_refseq": "ATP-binding cassette sub-family B member 5", "tax_id": 10116, "disease": "cystic fibrosis (Disease Ontology:DOID:1485)", "pathway": " (rno:314537); (R-RNO-382556)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "29393594", "class_list": "", "function": "Energy-dependent efflux transporter responsible for decreased drug accumulation in multidrug-resistant cells. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "7.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.1", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0042626 ATPase-coupled transmembrane transporter activity;GO:0008559 ABC-type xenobiotic transporter activity;GO:0016887 ATP hydrolysis activity;GO:0015562 efflux transmembrane transporter activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005886 plasma membrane;GO:0016324 apical plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0006869 lipid transport;GO:0030154 cell differentiation;GO:0042391 regulation of membrane potential;GO:0055085 transmembrane transport;GO:0009410 response to xenobiotic stimulus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4AEL4-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E9PSN4-1", "uniprot_id": [ { "id": "E9PSN4_RAT", "url": "https://www.uniprot.org/uniprot/E9PSN4", "type": "external" } ], "mass": 203525.0, "length": 1728, "protein_name": "Zinc finger CCCH type containing 13", "gene_name": "Zc3h13", "organism": "Rat", "refseq_name": "zinc finger CCCH domain-containing protein 13", "refseq_ac": [ { "id": "NP_001163942", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163942", "type": "external" } ], "gene_names_uniprotkb": "Zc3h13", "gene_names_refseq": "RGD1307729; 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Il3ra", "protein_names_uniprotkb": "Interleukin-3 receptor subunit alpha", "protein_names_refseq": "cytokine receptor-like protein CYRL; interleukin 3 receptor, alpha chain; interleukin-3 receptor subunit alpha precursor", "tax_id": 10116, "disease": "", "pathway": " (rno:246144)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "29393594", "class_list": "", "function": "Cell surface receptor for IL3 expressed on hematopoietic progenitor cells, monocytes and B-lymphocytes that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Ligand stimulation rapidly induces hetrodimerization with IL3RB, phosphorylation and enzyme activity of effector proteins such as JAK2 and PI3K that play a role in signaling cell proliferation and differentiation. Activation of JAK2 leads to STAT5-mediated transcriptional program., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004912 interleukin-3 receptor activity;GO:0019955 cytokine binding;GO:0004896 cytokine receptor activity;GO:0019978 interleukin-3 binding", "go_cellular_component": "GO:0016020 membrane;GO:0043235 receptor complex;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0038156 interleukin-3-mediated signaling pathway;GO:0008284 positive regulation of cell population proliferation;GO:0001558 regulation of cell growth;GO:0019221 cytokine-mediated signaling pathway;GO:0030224 monocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "E9PSX4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E9PSX7-1", "uniprot_id": [ { "id": "E9PSX7_RAT", "url": "https://www.uniprot.org/uniprot/E9PSX7", "type": "external" } ], "mass": 60207.0, "length": 548, "protein_name": "HIRA interacting protein 3", "gene_name": "Hirip3", "organism": "Rat", "refseq_name": "HIRA-interacting protein 3 isoform 1", "refseq_ac": [ { "id": "NP_001386591", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386591", "type": "external" } ], "gene_names_uniprotkb": "Hirip3", "gene_names_refseq": "Hirip3", "protein_names_uniprotkb": "HIRA interacting protein 3", "protein_names_refseq": "HIRA-interacting protein 3 isoform 1", "tax_id": 10116, "disease": "", "pathway": " (rno:361650)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000511 H2A-H2B histone complex chaperone activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus", "go_biological_process": "GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "E9PSX7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E9PT11-1", "uniprot_id": [ { "id": "E9PT11_RAT", "url": "https://www.uniprot.org/uniprot/E9PT11", "type": "external" } ], "mass": 44465.0, "length": 414, "protein_name": "Chromobox 6", "gene_name": "Cbx6", "organism": "Rat", "refseq_name": "chromobox protein homolog 6 isoform 1", "refseq_ac": [ { "id": "NP_001387975", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001387975", "type": "external" } ], "gene_names_uniprotkb": "Cbx6", "gene_names_refseq": "Cbx6", "protein_names_uniprotkb": "Chromobox 6", "protein_names_refseq": "chromobox homolog 6; chromobox protein homolog 6 isoform 1; chromobox protein homolog 6", "tax_id": 10116, "disease": "cancer (Disease Ontology:DOID:162); glioblastoma (Disease Ontology:DOID:3068)", "pathway": " (R-RNO-2559580); (R-RNO-8939243); (R-RNO-8943724)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0003727 single-stranded RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0016604 nuclear body;GO:0000785 chromatin;GO:0000792 heterochromatin", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E9PT11-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E9PT20-1", "uniprot_id": [ { "id": "E9PT20_RAT", "url": "https://www.uniprot.org/uniprot/E9PT20", "type": "external" } ], "mass": 124636.0, "length": 1143, "protein_name": "Tyrosine-protein kinase", "gene_name": "Abl1", "organism": "Rat", "refseq_name": "tyrosine-protein kinase ABL1", "refseq_ac": [ { "id": "NP_001094320", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094320", "type": "external" } ], "gene_names_uniprotkb": "Abl1", "gene_names_refseq": "Abl1; Abl", "protein_names_uniprotkb": "Tyrosine-protein kinase; 2.7.10.2", "protein_names_refseq": "Abelson murine leukemia viral (v-abl) oncogene homolog 1; c-abl oncogene 1, non-receptor tyrosine kinase; c-abl oncogene 1, receptor tyrosine kinase; tyrosine-protein kinase ABL1-like; tyrosine-protein kinase ABL1; v-abl Abelson murine leukemia viral oncogene 1", "tax_id": 10116, "disease": "oral squamous cell carcinoma (Disease Ontology:DOID:0050866); B-lymphoblastic leukemia/lymphoma (Disease Ontology:DOID:0080630); stomach cancer (Disease Ontology:DOID:10534); Parkinson's disease (Disease Ontology:DOID:14330); lung non-small cell carcinoma (Disease Ontology:DOID:3908); esophagus adenocarcinoma (Disease Ontology:DOID:4914); ureteral obstruction (Disease Ontology:DOID:5199); chronic myeloid leukemia (Disease Ontology:DOID:8552); acute myeloid leukemia (Disease Ontology:DOID:9119); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (rno:311860); (R-RNO-2029482); (R-RNO-525793); (R-RNO-5663213); (R-RNO-5685938); (R-RNO-5693565); (R-RNO-69231); (R-RNO-8939236); (R-RNO-9841922); (R-RNO-9860927)", "pathway_count": 10, "publication_count": 3, "publication_id_list": "32399753;32498644;33786723", "class_list": "", "function": "Abelson Kinases Mediate the Depression of Spontaneous Synaptic Activity Induced by Amyloid Beta 1-42 Peptides., [RefSeq, PubMed]; C-Abl Tyrosine Kinase-Mediated Neuronal Apoptosis in Subarachnoid Hemorrhage by Modulating the LRP-1-Dependent Akt/GSK3beta Survival Pathway., [RefSeq, PubMed]; C-Abl-p38alpha signaling pathway mediates dopamine neuron loss in trigeminal neuralgia., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.10.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.4", "type": "external" }, { "id": "2.7.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.32", "type": "external" }, { "id": "2.7.1.82", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.82", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0001784 phosphotyrosine residue binding;GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm", "go_biological_process": "GO:1903055 positive regulation of extracellular matrix organization;GO:0071103 DNA conformation change;GO:0072359 circulatory system development;GO:1903905 positive regulation of establishment of T cell polarity;GO:2000042 negative regulation of double-strand break repair via homologous recombination", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "E9PT20-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E9PT90-1", "uniprot_id": [ { "id": "E9PT90_RAT", "url": "https://www.uniprot.org/uniprot/E9PT90", "type": "external" } ], "mass": 74122.0, "length": 682, "protein_name": "Spartin", "gene_name": "Spart", "organism": "Rat", "refseq_name": "spartin isoform X2", "refseq_ac": [ { "id": "XP_006232428", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006232428", "type": "external" } ], "gene_names_uniprotkb": "Spart; Spg20", "gene_names_refseq": "Spart; Spg20", "protein_names_uniprotkb": "Spartin", "protein_names_refseq": "spartin isoform X2", "tax_id": 10116, "disease": "Troyer syndrome (Disease Ontology:DOID:0050886)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Lipophagy receptor that plays an important role in lipid droplet (LD) turnover in motor neurons. Localizes to LDs and interacts with components of the autophagy machinery, such as MAP1LC3A/C proteins to deliver LDs to autophagosomes for degradation via lipophagy. Lipid transfer protein required for lipid droplet degradation, including by lipophagy. Can bind and transfer all lipid species found in lipid droplets, from phospholipids to triglycerides and sterol esters but the direction of lipid transfer by spartin and its cargos are unknown. May be implicated in endosomal trafficking, or microtubule dynamics, or both. Participates in cytokinesis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding;GO:0008289 lipid binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005741 mitochondrial outer membrane;GO:0005811 lipid droplet;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0048698 negative regulation of collateral sprouting in absence of injury;GO:0006869 lipid transport;GO:0050905 neuromuscular process;GO:0051301 cell division;GO:0060612 adipose tissue development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E9PT90-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E9PTK4-1", "uniprot_id": [ { "id": "E9PTK4_RAT", "url": "https://www.uniprot.org/uniprot/E9PTK4", "type": "external" } ], "mass": 82710.0, "length": 745, "protein_name": "Threonine synthase-like 1", "gene_name": "Thnsl1", "organism": "Rat", "refseq_name": "threonine synthase-like 1 isoform X1", "refseq_ac": [ { "id": "XP_038951957", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038951957", "type": "external" } ], "gene_names_uniprotkb": "Thnsl1", "gene_names_refseq": "Thnsl1", "protein_names_uniprotkb": "Threonine synthase-like 1", "protein_names_refseq": "threonine synthase-like 1 isoform X1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E9PTK4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E9PTL1-1", "uniprot_id": [ { "id": "E9PTL1_RAT", "url": "https://www.uniprot.org/uniprot/E9PTL1", "type": "external" } ], "mass": 77312.0, "length": 686, "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "Rad17", "organism": "Rat", "refseq_name": "cell cycle checkpoint protein RAD17 isoform X1", "refseq_ac": [ { "id": "XP_006231910", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006231910", "type": "external" } ], "gene_names_uniprotkb": "Rad17", "gene_names_refseq": "Rad17", "protein_names_uniprotkb": "Cell cycle checkpoint protein RAD17", "protein_names_refseq": "cell cycle checkpoint protein RAD17 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-176187); (R-RNO-5685938); (R-RNO-5693607); (R-RNO-6804756); (R-RNO-69473)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. Has a weak ATPase activity required for binding to chromatin. Participates in the recruitment of the 9-1-1 (RAD1-RAD9-HUS1) complex and RHNO1 onto chromatin, and in CHEK1 activation. Involved in homologous recombination by mediating recruitment of the MRN complex to DNA damage sites. May also serve as a sensor of DNA replication progression., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0003689 DNA clamp loader activity;GO:0140463 chromatin-protein adaptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0000785 chromatin;GO:0035861 site of double-strand break", "go_biological_process": "GO:1990166 protein localization to site of double-strand break;GO:0006281 DNA repair;GO:0006974 DNA damage response;GO:0031573 mitotic intra-S DNA damage checkpoint signaling;GO:0042325 regulation of phosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "E9PTL1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E9PTR3-1", "uniprot_id": [ { "id": "E9PTR3_RAT", "url": "https://www.uniprot.org/uniprot/E9PTR3", "type": "external" } ], "mass": 159040.0, "length": 1373, "protein_name": "Ribonuclease 3", "gene_name": "Drosha", "organism": "Rat", "refseq_name": "ribonuclease 3", "refseq_ac": [ { "id": "NP_001101125", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101125", "type": "external" } ], "gene_names_uniprotkb": "Drosha", "gene_names_refseq": "Drosha; Etohi2; RGD1307626; Rn3; Rnasen", "protein_names_uniprotkb": "Ribonuclease 3; 3.1.26.3; Ribonuclease III; protein Drosha", "protein_names_refseq": "drosha, ribonuclease type III; ethanol induced 2; ribonuclease 3; ribonuclease III, nuclear; ribonuclease type III, nuclear", "tax_id": 10116, "disease": "brain disease (Disease Ontology:DOID:936)", "pathway": " (rno:310159)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "36222340", "class_list": "", "function": "Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies. Plays a role in growth homeostasis in response to autophagy in motor neurons., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; The 24-h pattern of dgcr8, drosha, and dicer expression in the rat suprachiasmatic nuclei and peripheral tissues and its modulation by angiotensin II., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0042803 protein homodimerization activity;GO:0046872 metal ion binding;GO:0046332 SMAD binding;GO:0001530 lipopolysaccharide binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm", "go_biological_process": "GO:0010628 positive regulation of gene expression;GO:0050829 defense response to Gram-negative bacterium;GO:0050830 defense response to Gram-positive bacterium;GO:0050727 regulation of inflammatory response;GO:0010586 miRNA metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "E9PTR3-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E9PTS6-1", "uniprot_id": [ { "id": "E9PTS6_RAT", "url": "https://www.uniprot.org/uniprot/E9PTS6", "type": "external" } ], "mass": 54027.0, "length": 501, "protein_name": "KLF transcription factor 11", "gene_name": "Klf11", "organism": "Rat", "refseq_name": "Krueppel-like factor 11", "refseq_ac": [ { "id": "NP_001032431", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032431", "type": "external" } ], "gene_names_uniprotkb": "Klf11", "gene_names_refseq": "Klf11; Tcfcp2l2", "protein_names_uniprotkb": "KLF transcription factor 11", "protein_names_refseq": "Krueppel-like factor 11; Kruppel-like factor 11; transcription factor CP2-like 2", "tax_id": 10116, "disease": "maturity-onset diabetes of the young type 7 (Disease Ontology:DOID:0111106); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (rno:313994)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "21592955;25739536;27848055", "class_list": "", "function": "An important role for KLF11 in the regulation of INS transcription via the novel c.-331 KLF site., [RefSeq, PubMed]; In hypoxia/reoxygenation injury of rat cardiomyocytes, inhibition of KLF11 by siRNA suppressed apoptosis, the activity of caspase3, the expression of cleaved-caspase3 and cytochrome C in the cytoplasm and the damage of mitochondrial membrane. KLF11 knockdown elevated the expression of p-JAK2 and p-STAT3. KLF11 silencing protects against H/R injury by activating the JAK2/STAT3 signaling pathway ., [RefSeq, PubMed]; Kruppel-like factor 11 protein is up-regulated following chronic exposure to stress or ethanol in a region-specific manner and may contribute to pro-apoptotic signaling in ethanol-treated rats., [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000976 transcription cis-regulatory region binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:1990859 cellular response to endothelin;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0008285 negative regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "E9PTS6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E9PTX9-1", "uniprot_id": [ { "id": "E9PTX9_RAT", "url": "https://www.uniprot.org/uniprot/E9PTX9", "type": "external" } ], "mass": 130367.0, "length": 1203, "protein_name": "Solute carrier family 12 member 2", "gene_name": "Slc12a2", "organism": "Rat", "refseq_name": "solute carrier family 12 member 2", "refseq_ac": [ { "id": "NP_113986", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113986", "type": "external" } ], "gene_names_uniprotkb": "Slc12a2", "gene_names_refseq": "Bsc2; Nkcc1; Slc12a2", "protein_names_uniprotkb": "Solute carrier family 12 member 2", "protein_names_refseq": "solute carrier family 12 (sodium/potassium/chloride transporter), member 2; solute carrier family 12 (sodium/potassium/chloride transporters), member 2; solute carrier family 12 member 2", "tax_id": 10116, "disease": "autosomal dominant nonsyndromic deafness 78 (Disease Ontology:DOID:0112159); sensorineural hearing loss (Disease Ontology:DOID:10003); hypertension (Disease Ontology:DOID:10763); epilepsy (Disease Ontology:DOID:1826); transient cerebral ischemia (Disease Ontology:DOID:224); middle cerebral artery infarction (Disease Ontology:DOID:3525)", "pathway": " (rno:83629); (R-RNO-426117)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "22673903;35729645;37328833;37458846;37830575;38160798", "class_list": "", "function": "Age-appropriate potassium clearance from perinatal cerebrospinal fluid depends on choroid plexus NKCC1. Publication Status: Online-Only, [RefSeq, PubMed]; DNA demethylation in the hypothalamus promotes transcription of Agtr1a and Slc12a2 and hypertension development., [RefSeq, PubMed]; Dietary Na[+] depletion up-regulates NKCC1 expression and enhances electrogenic Cl[-] secretion in rat proximal colon. Publication Status: Online-Only, [RefSeq, PubMed]; NKCC1 and KCC2 Chloride Transporters Have Different Membrane Dynamics on the Surface of Hippocampal Neurons. Publication Status: Online-Only, [RefSeq, PubMed]; NLRP3 inflammasome-mediated choroid plexus hypersecretion contributes to hydrocephalus after intraventricular hemorrhage via phosphorylated NKCC1 channels. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0051087 protein-folding chaperone binding;GO:0051879 Hsp90 protein binding;GO:0008519 ammonium channel activity;GO:0015079 potassium ion transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane;GO:0043025 neuronal cell body;GO:0016324 apical plasma membrane;GO:0030659 cytoplasmic vesicle membrane", "go_biological_process": "GO:1990869 cellular response to chemokine;GO:0030644 intracellular chloride ion homeostasis;GO:0061044 negative regulation of vascular wound healing;GO:0070634 transepithelial ammonium transport;GO:0050910 detection of mechanical stimulus involved in sensory perception of sound", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "E9PTX9-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E9PTY0-1", "uniprot_id": [ { "id": "E9PTY0_RAT", "url": "https://www.uniprot.org/uniprot/E9PTY0", "type": "external" } ], "mass": 117502.0, "length": 1010, "protein_name": "Leucine-rich repeat and coiled-coil domain-containing protein 1", "gene_name": "Lrrcc1", "organism": "Rat", "refseq_name": "leucine-rich repeat and coiled-coil domain-containing protein 1 isoform X1", "refseq_ac": [ { "id": "XP_038957738", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038957738", "type": "external" } ], "gene_names_uniprotkb": "Lrrcc1", "gene_names_refseq": "Lrrcc1; Sap2", "protein_names_uniprotkb": "Leucine-rich repeat and coiled-coil domain-containing protein 1", "protein_names_refseq": "leucine-rich repeat and coiled-coil domain-containing protein 1 isoform X1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Required for the organization of the mitotic spindle. Maintains the structural integrity of centrosomes during mitosis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005813 centrosome;GO:0005814 centriole", "go_biological_process": "GO:0051301 cell division", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "E9PTY0-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E9PTZ1-1", "uniprot_id": [ { "id": "E9PTZ1_RAT", "url": "https://www.uniprot.org/uniprot/E9PTZ1", "type": "external" } ], "mass": 110354.0, "length": 1033, "protein_name": "Platelet endothelial aggregation receptor 1", "gene_name": "Pear1", "organism": "Rat", "refseq_name": "platelet endothelial aggregation receptor 1 isoform X2", "refseq_ac": [ { "id": "XP_038957982", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038957982", "type": "external" } ], "gene_names_uniprotkb": "Pear1", "gene_names_refseq": "Pear1; RGD1305653", "protein_names_uniprotkb": "Platelet endothelial aggregation receptor 1; Multiple epidermal growth factor-like domains protein 12", "protein_names_refseq": "platelet endothelial aggregation receptor 1 isoform X2", "tax_id": 10116, "disease": "neurodegenerative disease (Disease Ontology:DOID:1289); myopathy (Disease Ontology:DOID:423)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for SVEP1-mediated platelet activation, via its interaction with SVEP1 and subsequent activation of AKT/mTOR signaling. May be involved in the early stages of hematopoiesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030027 lamellipodium", "go_biological_process": "GO:0070527 platelet aggregation;GO:0043491 phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0010572 positive regulation of platelet activation;GO:0043654 recognition of apoptotic cell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E9PTZ1-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E9PTZ7-1", "uniprot_id": [ { "id": "E9PTZ7_RAT", "url": "https://www.uniprot.org/uniprot/E9PTZ7", "type": "external" } ], "mass": 39731.0, "length": 350, "protein_name": "RT1 class Ia, locus A2", "gene_name": "Rt1-ec3", "organism": "Rat", "refseq_name": "RT1 class Ia, locus A2 isoform X6", "refseq_ac": [ { "id": "XP_017457034", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017457034", "type": "external" } ], "gene_names_uniprotkb": "Rt1-ec3; ENSRNOG00000069480; RT1-A2", "gene_names_refseq": "RT1-A2n; RT1-A2; RT1.A2(N); RT1A-2", "protein_names_uniprotkb": "RT1 class Ia, locus A2", "protein_names_refseq": "RT1 class Ia, locus A2 isoform X6", "tax_id": 10116, "disease": "Stevens-Johnson syndrome (Disease Ontology:DOID:0050426); colitis (Disease Ontology:DOID:0060180); Cytomegalovirus retinitis (Disease Ontology:DOID:0080160); COVID-19 (Disease Ontology:DOID:0080600); ankylosing spondylitis 1 (Disease Ontology:DOID:0080603); erythema nodosum (Disease Ontology:DOID:0080750); occupational asthma (Disease Ontology:DOID:0080820); birdshot chorioretinopathy (Disease Ontology:DOID:0111079); psoriasis 1 (Disease Ontology:DOID:0111286); sensorineural hearing loss (Disease Ontology:DOID:10003); spondyloarthropathy (Disease Ontology:DOID:1123); trachoma (Disease Ontology:DOID:11265); sarcoidosis (Disease Ontology:DOID:11335); retinal vasculitis (Disease Ontology:DOID:11563); otosclerosis (Disease Ontology:DOID:12185); Graves' disease (Disease Ontology:DOID:12361); respiratory syncytial virus infectious disease (Disease Ontology:DOID:1273); retinopathy of prematurity (Disease Ontology:DOID:13025); uveitis (Disease Ontology:DOID:13141); Behcet's disease (Disease Ontology:DOID:13241); anterior uveitis (Disease Ontology:DOID:1407); cystic fibrosis (Disease Ontology:DOID:1485); hepatitis C (Disease Ontology:DOID:1883); Takayasu's arteritis (Disease Ontology:DOID:2508); synovitis (Disease Ontology:DOID:2703); dermatitis (Disease Ontology:DOID:2723); asthma (Disease Ontology:DOID:2841); severe acute respiratory syndrome (Disease Ontology:DOID:2945); cerebral infarction (Disease Ontology:DOID:3526); acute retinal necrosis syndrome (Disease Ontology:DOID:3611); thrombophlebitis (Disease Ontology:DOID:3875); tuberculosis (Disease Ontology:DOID:399); cervical cancer (Disease Ontology:DOID:4362); allergic rhinitis (Disease Ontology:DOID:4481); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); uveal melanoma (Disease Ontology:DOID:6039); reactive arthritis (Disease Ontology:DOID:6196); myositis (Disease Ontology:DOID:633); ankylosing spondylitis (Disease Ontology:DOID:7147); diabetic retinopathy (Disease Ontology:DOID:8947); allergic asthma (Disease Ontology:DOID:9415); Meniere's disease (Disease Ontology:DOID:9849); alopecia (Disease Ontology:DOID:987); mitral valve prolapse (Disease Ontology:DOID:988)", "pathway": " (R-RNO-1236974); (R-RNO-1236977); (R-RNO-198933); (R-RNO-6798695); (R-RNO-983170)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in the presentation of foreign antigens to the immune system., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 44, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046703 natural killer cell lectin-like receptor binding;GO:0005102 signaling receptor binding;GO:0030881 beta-2-microglobulin binding;GO:0042605 peptide antigen binding;GO:0042608 T cell receptor binding", "go_cellular_component": "GO:0032398 MHC class Ib protein complex;GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib;GO:0002715 regulation of natural killer cell mediated immunity;GO:0002717 positive regulation of natural killer cell mediated immunity;GO:0032736 positive regulation of interleukin-13 production;GO:0032759 positive regulation of TRAIL production", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E9PTZ7-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LM38-1", "uniprot_id": [ { "id": "F1LM38_RAT", "url": "https://www.uniprot.org/uniprot/F1LM38", "type": "external" } ], "mass": 64688.0, "length": 613, "protein_name": "KH homology domain-containing protein 4", "gene_name": "Khdc4", "organism": "Rat", "refseq_name": "KH homology domain-containing protein 4", "refseq_ac": [ { "id": "NP_001386167", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386167", "type": "external" } ], "gene_names_uniprotkb": "Khdc4; RGD1565775", "gene_names_refseq": "Blom7; Khdc4; RGD1565775", "protein_names_uniprotkb": "KH homology domain-containing protein 4; Brings lots of money 7; Pre-mRNA Splicing factor protein khdc4", "protein_names_refseq": "KH homology domain-containing protein 4; nuclear ribonucleoprotein K homology domain protein", "tax_id": 10116, "disease": "", "pathway": " (rno:361980)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "RNA-binding protein involved in pre-mRNA splicing. Interacts with the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome. Involved in regulating splice site selection. Binds preferentially RNA with A/C rich sequences and poly-C stretches., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005681 spliceosomal complex", "go_biological_process": "GO:0006376 mRNA splice site recognition", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LM38-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LM66-1", "uniprot_id": [ { "id": "F1LM66_RAT", "url": "https://www.uniprot.org/uniprot/F1LM66", "type": "external" } ], "mass": 109102.0, "length": 969, "protein_name": "116 kDa U5 small nuclear ribonucleoprotein component", "gene_name": "Eftud2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Eftud2", "gene_names_refseq": "", "protein_names_uniprotkb": "116 kDa U5 small nuclear ribonucleoprotein component; U5 snRNP-specific protein, 116 kDa", "protein_names_refseq": "", "tax_id": 10116, "disease": "mandibulofacial dysostosis, Guion-Almeida type (Disease Ontology:DOID:0080196); esophageal atresia (Disease Ontology:DOID:10485); microcephaly (Disease Ontology:DOID:10907); hepatitis B (Disease Ontology:DOID:2043); Treacher Collins syndrome (Disease Ontology:DOID:2908); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (rno:287739); (R-RNO-72163); (R-RNO-72165)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes. Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0030623 U5 snRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0016607 nuclear speck;GO:0005681 spliceosomal complex", "go_biological_process": "GO:0071466 cellular response to xenobiotic stimulus;GO:0042220 response to cocaine;GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1LM66-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LMA5-1", "uniprot_id": [ { "id": "F1LMA5_RAT", "url": "https://www.uniprot.org/uniprot/F1LMA5", "type": "external" } ], "mass": 32360.0, "length": 284, "protein_name": "Friend virus susceptibility 1", "gene_name": "Fv1", "organism": "Rat", "refseq_name": "uncharacterized protein C19orf48 homolog", "refseq_ac": [ { "id": "NP_001014040", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014040", "type": "external" } ], "gene_names_uniprotkb": "Fv1", "gene_names_refseq": "Fv1; RGD1309326", "protein_names_uniprotkb": "Friend virus susceptibility 1", "protein_names_refseq": "uncharacterized protein C19orf48 homolog", "tax_id": 10116, "disease": "", "pathway": " (rno:308568)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005794 Golgi apparatus", "go_biological_process": "GO:0009615 response to virus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LMA5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LMC1-1", "uniprot_id": [ { "id": "F1LMC1_RAT", "url": "https://www.uniprot.org/uniprot/F1LMC1", "type": "external" } ], "mass": 61011.0, "length": 575, "protein_name": "WT1 interacting protein", "gene_name": "Wtip", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Wtip", "gene_names_refseq": "", "protein_names_uniprotkb": "WT1 interacting protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:361552); (R-RNO-1234176)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0003714 transcription corepressor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005912 adherens junction;GO:0000932 P-body;GO:0005667 transcription regulator complex;GO:0070161 anchoring junction", "go_biological_process": "GO:0001666 response to hypoxia;GO:0006355 regulation of DNA-templated transcription;GO:0007010 cytoskeleton organization;GO:0035278 miRNA-mediated gene silencing by inhibition of translation;GO:0035195 miRNA-mediated post-transcriptional gene silencing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LMC1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0DSP1-1", "uniprot_id": [ { "id": "SORL_RAT", "url": "https://www.uniprot.org/uniprot/P0DSP1", "type": "external" } ], "mass": 247316.0, "length": 2215, "protein_name": "Sortilin-related receptor", "gene_name": "Sorl1", "organism": "Rat", "refseq_name": "sortilin-related receptor precursor", "refseq_ac": [ { "id": "NP_445971", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_445971", "type": "external" } ], "gene_names_uniprotkb": "Sorl1", "gene_names_refseq": "Lr11; RGD619914; SorLA; Sorl1", "protein_names_uniprotkb": "Sortilin-related receptor; LDLR relative with 11 ligand-binding repeats; LR11; Low-density lipoprotein receptor relative with 11 ligand-binding repeats; SorLA; Sorting protein-related receptor containing LDLR class A repeats", "protein_names_refseq": "LDLR relative with 11 ligand-binding repeats; low-density lipoprotein receptor relative with 11 ligand-binding repeats; sortilin-related receptor precursor; sortilin-related receptor, LDLR class A repeats-containing; sortilin-related receptor-like; sorting protein-related receptor containing LDLR class A repeats", "tax_id": 10116, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652)", "pathway": " (rno:300652)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "17332490;18683930;21994944;23333276;25967121;29393594;30625365;9510025", "class_list": "", "function": "Sorting receptor that directs several proteins to their correct location within the cell. Along with AP-1 complex, involved Golgi apparatus - endosome sorting. Sorting receptor for APP, regulating its intracellular trafficking and processing into amyloidogenic-beta peptides. Retains APP in the trans-Golgi network, hence preventing its transit through late endosomes where amyloid beta peptides Abeta40 and Abeta42 are generated. May also sort newly produced amyloid-beta peptides to lysosomes for catabolism. Does not affect APP trafficking from the endoplasmic reticulum to Golgi compartments. Sorting receptor for the BDNF receptor NTRK2/TRKB that facilitates NTRK2 trafficking between synaptic plasma membranes, postsynaptic densities and cell soma, hence positively regulates BDNF signaling by controlling the intracellular location of its receptor (By similarity). Sorting receptor for GDNF that promotes GDNF regulated, but not constitutive secretion (PubMed:21994944). Sorting receptor for the GDNF-GFRA1 complex, directing it from the cell surface to endosomes. GDNF is then targeted to lysosomes and degraded, while its receptor GFRA1 recycles back to the cell membrane, resulting in a GDNF clearance pathway. The SORL1-GFRA1 complex further targets RET for endocytosis, but not for degradation, affecting GDNF-induced neurotrophic activities (PubMed:23333276). Sorting receptor for ERBB2/HER2. Regulates ERBB2 subcellular distribution by promoting its recycling after internalization from endosomes back to the plasma membrane, hence stimulating phosphoinositide 3-kinase (PI3K)-dependent ERBB2 signaling (By similarity). Sorting receptor for lipoprotein lipase LPL. Promotes LPL localization to endosomes and later to the lysosomes, leading to degradation of newly synthesized LPL. Potential sorting receptor for APOA5, inducing APOA5 internalization to early endosomes, then to late endosomes, wherefrom a portion is sent to lysosomes and degradation, another portion is sorted to the trans-Golgi network. Sorting receptor for the insulin receptor INSR. Promotes recycling of internalized INSR via the Golgi apparatus back to the cell surface, thereby preventing lysosomal INSR catabolism, increasing INSR cell surface expression and strengthening insulin signal reception in adipose tissue. Does not affect INSR internalization (By similarity). Plays a role in renal ion homeostasis, controlling the phospho-regulation of SLC12A1/NKCC2 by STK39/SPAK kinase and PPP3CB/calcineurin A beta phosphatase, possibly through intracellular sorting of STK39 and PPP3CB (PubMed:25967121). Stimulates, via the N-terminal ectodomain, the proliferation and migration of smooth muscle cells, possibly by increasing cell surface expression of the urokinase receptor uPAR/PLAUR. This may promote extracellular matrix proteolysis and hence facilitate cell migration. By acting on the migration of intimal smooth muscle cells, may accelerate intimal thickening following vascular injury (By similarity). Stimulates proliferation and migration monocytes/macrophages. Through its action on intimal smooth muscle cells and macrophages, may accelerate intimal thickening and macrophage foam cell formation in the process of atherosclerosis (By similarity). Regulates hypoxia-enhanced adhesion of hematopoietic stem and progenitor cells to the bone marrow stromal cells via a PLAUR-mediated pathway. This function is mediated by the N-terminal ectodomain (By similarity). Metabolic regulator, which functions to maintain the adequate balance between lipid storage and oxidation in response to changing environmental conditions, such as temperature and diet. The N-terminal ectodomain negatively regulates adipose tissue energy expenditure, acting through the inhibition the BMP/Smad pathway (By similarity). Sorting receptor that may regulate signaling by the heterodimeric neurotrophic cytokine CLCF1-CRLF1 bound to the CNTFR receptor by promoting the endocytosis of the tripartite complex CLCF1-CRLF1-CNTFR and lysosomal degradation. Might regulate IL6 signaling, decreasing cis signaling, while up-regulating trans signaling (By similarity)., [UniProtKB, PubMed, UniProtKB, PubMed, UniProtKB, PubMed]", "predicted_glycosites": 28, "predicted_n_glycosites": 27, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 28, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0001540 amyloid-beta binding;GO:0031267 small GTPase binding;GO:0030169 low-density lipoprotein particle binding;GO:0019828 aspartic-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005615 extracellular space;GO:0005641 nuclear envelope lumen;GO:0005768 endosome;GO:0005769 early endosome", "go_biological_process": "GO:0001960 negative regulation of cytokine-mediated signaling pathway;GO:1902966 positive regulation of protein localization to early endosome;GO:1904179 positive regulation of adipose tissue development;GO:0045053 protein retention in Golgi apparatus;GO:0007218 neuropeptide signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P0DSP1-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0100000011001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZZZ4-1", "uniprot_id": [ { "id": "A0A8I5ZZZ4_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZZZ4", "type": "external" } ], "mass": 35099.0, "length": 321, "protein_name": "RAD52 motif-containing protein 1", "gene_name": "Rdm1", "organism": "Rat", "refseq_name": "RAD52 motif-containing protein 1 isoform X1", "refseq_ac": [ { "id": "XP_063124815", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063124815", "type": "external" } ], "gene_names_uniprotkb": "Rdm1", "gene_names_refseq": "Rad52b; 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RGD1565557", "protein_names_uniprotkb": "Aprataxin and PNK-like factor; Apurinic-apyrimidinic endonuclease APLF", "protein_names_refseq": "aprataxin and PNK-like factor isoform X1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity;GO:0008408 3'-5' exonuclease activity;GO:0072572 poly-ADP-D-ribose binding;GO:0008270 zinc ion binding;GO:0000166 nucleotide binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0035861 site of double-strand break;GO:0090734 site of DNA damage", "go_biological_process": "GO:0006302 double-strand break repair;GO:0010717 regulation of epithelial to mesenchymal transition;GO:0006281 DNA repair;GO:0006974 DNA damage response;GO:0006303 double-strand break repair via nonhomologous end joining", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F6Q5G6-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F7FKH2-1", "uniprot_id": [ { "id": "F7FKH2_RAT", "url": "https://www.uniprot.org/uniprot/F7FKH2", "type": "external" } ], "mass": 76865.0, "length": 658, "protein_name": "Zinc finger MYND domain-containing protein 11", "gene_name": "Zmynd11", "organism": "Rat", "refseq_name": "zinc finger MYND domain-containing protein 11 isoform beta", "refseq_ac": [ { "id": "NP_976243", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_976243", "type": "external" } ], "gene_names_uniprotkb": "Zmynd11", "gene_names_refseq": "BS69; Zmynd11", "protein_names_uniprotkb": "Zinc finger MYND domain-containing protein 11", "protein_names_refseq": "zinc finger MYND domain-containing protein 11 isoform beta; zinc finger MYND domain-containing protein 11; zinc finger, MYND domain containing 11", "tax_id": 10116, "disease": "autosomal dominant intellectual developmental disorder 30 (Disease Ontology:DOID:0070060); stomach cancer (Disease Ontology:DOID:10534)", "pathway": " (rno:291259)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "17127430", "class_list": "", "function": "BS69 may function either as a transcriptional repressor or as a transcriptional activator depending on its regulatory partner. Publication Status: Online-Only, [RefSeq, PubMed]; Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Binds non-specifically to dsDNA. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003714 transcription corepressor activity;GO:0003690 double-stranded DNA binding;GO:0140003 histone H3K36me3 reader activity;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005694 chromosome", "go_biological_process": "GO:0034243 regulation of transcription elongation by RNA polymerase II;GO:0051607 defense response to virus;GO:0043124 negative regulation of canonical NF-kappaB signal transduction;GO:0009966 regulation of signal transduction;GO:2001237 negative regulation of extrinsic apoptotic signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F7FKH2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A7X8-1", "uniprot_id": [ { "id": "A0A8I6A7X8_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A7X8", "type": "external" } ], "mass": 50176.0, "length": 451, "protein_name": "Periphilin 1", "gene_name": "Pphln1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Pphln1", "gene_names_refseq": "", "protein_names_uniprotkb": "Periphilin 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:366975); (R-RNO-9843970)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005634 nucleus;GO:0000785 chromatin;GO:0000792 heterochromatin;GO:0140286 HUSH2 complex", "go_biological_process": "GO:0045892 negative regulation of DNA-templated transcription;GO:0045814 negative regulation of gene expression, epigenetic;GO:0097355 protein localization to heterochromatin;GO:0032480 negative regulation of type I interferon production;GO:0140719 constitutive heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I6A7X8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LND0-1", "uniprot_id": [ { "id": "F1LND0_RAT", "url": "https://www.uniprot.org/uniprot/F1LND0", "type": "external" } ], "mass": 158173.0, "length": 1608, "protein_name": "Collagen alpha-1(XVI) chain", "gene_name": "Col16a1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Col16a1", "gene_names_refseq": "", "protein_names_uniprotkb": "Collagen alpha-1(XVI) chain", "protein_names_refseq": "", "tax_id": 10116, "disease": "dilated cardiomyopathy (Disease Ontology:DOID:12930)", "pathway": " (rno:366474)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Involved in mediating cell attachment and inducing integrin-mediated cellular reactions, such as cell spreading and alterations in cell morphology., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding", "go_cellular_component": "", "go_biological_process": "GO:0007155 cell adhesion;GO:0033627 cell adhesion mediated by integrin;GO:0051894 positive regulation of focal adhesion assembly;GO:0071230 cellular response to amino acid stimulus;GO:0033622 integrin activation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1LND0-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LXS3-1", "uniprot_id": [ { "id": "F1LXS3_RAT", "url": "https://www.uniprot.org/uniprot/F1LXS3", "type": "external" } ], "mass": 101643.0, "length": 912, "protein_name": "Matrilin-2", "gene_name": "Matn2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Matn2", "gene_names_refseq": "", "protein_names_uniprotkb": "Matrilin-2", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:299996)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in matrix assembly., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0031012 extracellular matrix;GO:0005604 basement membrane;GO:0120216 matrilin complex", "go_biological_process": "GO:0031175 neuron projection development;GO:0001764 neuron migration;GO:0048678 response to axon injury;GO:0007411 axon guidance;GO:0008347 glial cell migration", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LXS3-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZYZ8-1", "uniprot_id": [ { "id": "A0A8I5ZYZ8_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZYZ8", "type": "external" } ], "mass": 40548.0, "length": 369, "protein_name": "NEDD8-conjugating enzyme UBC12", "gene_name": "Chmp2a; Ube2m", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Chmp2a; Ube2m; Chmp2a; Ube2m", "gene_names_refseq": "", "protein_names_uniprotkb": "NEDD8-conjugating enzyme UBC12; 2.3.2.34; NEDD8 carrier protein; NEDD8-conjugating enzyme Ubc12; Ubiquitin-conjugating enzyme E2 M", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:361509); (R-RNO-2173789); (R-RNO-5607761); (R-RNO-5676590); (R-RNO-8951664); (R-RNO-983168)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. Involved in cell proliferation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "2.3.2.32", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.32", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "2.3.2.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.24", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "6.2.1.45", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.45", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.30", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.30", "type": "external" }, { "id": "6.2.1.64", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.64", "type": "external" } ], "go_molecular_function": "GO:0019904 protein domain specific binding;GO:0031210 phosphatidylcholine binding;GO:0180020 membrane bending activity;GO:0005524 ATP binding;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0000815 ESCRT III complex;GO:0005828 kinetochore microtubule;GO:0000421 autophagosome membrane;GO:0005635 nuclear envelope;GO:0005643 nuclear pore", "go_biological_process": "GO:0001778 plasma membrane repair;GO:0010324 membrane invagination;GO:0010824 regulation of centrosome duplication;GO:0031468 nuclear membrane reassembly;GO:0039702 viral budding via host ESCRT complex", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I5ZYZ8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LTS3-1", "uniprot_id": [ { "id": "F1LTS3_RAT", "url": "https://www.uniprot.org/uniprot/F1LTS3", "type": "external" } ], "mass": 73206.0, "length": 651, "protein_name": "Regulator of DNA class I crossover intermediates 1", "gene_name": "Redic1", "organism": "Rat", "refseq_name": "regulator of DNA class I crossover intermediates 1 isoform 1", "refseq_ac": [ { "id": "NP_001419037", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001419037", "type": "external" } ], "gene_names_uniprotkb": "Redic1; 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Zfp709l2", "gene_names_refseq": "Zfp709l2; Zfp870", "protein_names_uniprotkb": "Zinc finger protein 870", "protein_names_refseq": "zinc finger protein 709-like 2", "tax_id": 10116, "disease": "", "pathway": " (rno:362845)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M9J2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LRT4-1", "uniprot_id": [ { "id": "F1LRT4_RAT", "url": "https://www.uniprot.org/uniprot/F1LRT4", "type": "external" } ], "mass": 57323.0, "length": 508, "protein_name": "Coiled-coil domain containing 125", "gene_name": "Ccdc125", "organism": "Rat", "refseq_name": "coiled-coil domain-containing protein 125", "refseq_ac": [ { "id": "NP_001128233", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001128233", "type": "external" } ], "gene_names_uniprotkb": "Ccdc125", "gene_names_refseq": "Ccdc125; 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Zfp426l; Zfp426; Znf266", "protein_names_uniprotkb": "Zinc finger protein 266", "protein_names_refseq": "zinc finger protein 426-like; zinc finger protein 426", "tax_id": 10116, "disease": "", "pathway": " (rno:367034); (R-RNO-212436)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "29393594", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1MAL0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0RAV7-1", "uniprot_id": [ { "id": "M0RAV7_RAT", "url": "https://www.uniprot.org/uniprot/M0RAV7", "type": "external" } ], "mass": 96127.0, "length": 871, "protein_name": "Adhesion G-protein coupled receptor D1", "gene_name": "Adgrd1", "organism": "Rat", "refseq_name": "adhesion G protein-coupled receptor D1 isoform 2", "refseq_ac": [ { "id": "NP_001419044", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001419044", "type": "external" } ], "gene_names_uniprotkb": "Adgrd1", "gene_names_refseq": "Adgrd1; 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Also activated by methenolone drug. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. ADGRD1 is coupled to G(s) G proteins and mediates activation of adenylate cyclase activity. 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scavenger receptor class F member 1 precursor", "tax_id": 10116, "disease": "", "pathway": " (rno:303313)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "31721324;33686740", "class_list": "", "function": "LncRNA BC088259 promotes Schwann cell migration through Vimentin following peripheral nerve injury., [RefSeq, PubMed]; SCARF1 promotes M2 polarization of Kupffer cells via calcium-dependent PI3K-AKT-STAT3 signalling to improve liver transplantation., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005044 scavenger receptor activity;GO:0030169 low-density lipoprotein particle binding", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0007155 cell adhesion;GO:0048680 positive regulation of axon regeneration;GO:0010976 positive regulation of neuron projection development;GO:0016322 neuron remodeling;GO:0016358 dendrite development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8I5ZRK9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LWT0-1", "uniprot_id": [ { "id": "SIMC1_RAT", "url": "https://www.uniprot.org/uniprot/F1LWT0", "type": "external" } ], "mass": 136789.0, "length": 1266, "protein_name": "SUMO-interacting motif-containing protein 1", "gene_name": "Simc1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Simc1; LOC100361684; Pleiad", "gene_names_refseq": "", "protein_names_uniprotkb": "SUMO-interacting motif-containing protein 1; Platform element for inhibition of autolytic degradation", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:100361684)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Inhibits the protease activity of CAPN3. May play a role in SMC5-SMC6 complex recruitment for viral restriction. Forms a complex with SLF2 and this complex is required to recruit SMC5-SMC6 complex to PML nuclear bodies and sites of viral replication., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030414 peptidase inhibitor activity;GO:0032184 SUMO polymer binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0030017 sarcomere;GO:0016605 PML body", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LWT0-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R9A9-1", "uniprot_id": [ { "id": "M0R9A9_RAT", "url": "https://www.uniprot.org/uniprot/M0R9A9", "type": "external" } ], "mass": 228843.0, "length": 2053, "protein_name": "Centrosomal protein of 164 kDa", "gene_name": "Cep164", "organism": "Rat", "refseq_name": "centrosomal protein of 164 kDa isoform X1", "refseq_ac": [ { "id": "XP_038938279", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038938279", "type": "external" } ], "gene_names_uniprotkb": "Cep164", "gene_names_refseq": "Cep164; RGD1560988; RGD1561243", "protein_names_uniprotkb": "Centrosomal protein of 164 kDa", "protein_names_refseq": "centrosomal protein of 164 kDa isoform X1", "tax_id": 10116, "disease": "nephronophthisis 15 (Disease Ontology:DOID:0111123); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (rno:363055); (R-RNO-2565942); (R-RNO-380259); (R-RNO-380270); (R-RNO-380284); (R-RNO-380320); (R-RNO-5620912); (R-RNO-8854518)", "pathway_count": 8, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in microtubule organization and/or maintenance for the formation of primary cilia (PC), a microtubule-based structure that protrudes from the surface of epithelial cells. Plays a critical role in G2/M checkpoint and nuclear divisions. A key player in the DNA damage-activated ATR/ATM signaling cascade since it is required for the proper phosphorylation of H2AX, RPA, CHEK2 and CHEK1. Plays a critical role in chromosome segregation, acting as a mediator required for the maintenance of genomic stability through modulation of MDC1, RPA and CHEK1., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005814 centriole;GO:0097539 ciliary transition fiber;GO:0005654 nucleoplasm;GO:0005813 centrosome", "go_biological_process": "GO:0006281 DNA repair;GO:0051301 cell division;GO:0030030 cell projection organization;GO:0060271 cilium assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R9A9-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LUQ3-1", "uniprot_id": [ { "id": "F1LUQ3_RAT", "url": "https://www.uniprot.org/uniprot/F1LUQ3", "type": "external" } ], "mass": 225060.0, "length": 2058, "protein_name": "Methylcytosine dioxygenase TET", "gene_name": "Tet1", "organism": "Rat", "refseq_name": "methylcytosine dioxygenase TET1 isoform X1", "refseq_ac": [ { "id": "XP_038955252", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038955252", "type": "external" } ], "gene_names_uniprotkb": "Tet1", "gene_names_refseq": "Tet1", "protein_names_uniprotkb": "Methylcytosine dioxygenase TET; 1.14.11.80", "protein_names_refseq": "methylcytosine dioxygenase TET1 isoform X1", "tax_id": 10116, "disease": "hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.80", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.80", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0070579 DNA 5-methylcytosine dioxygenase activity;GO:0005506 iron ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome;GO:0005654 nucleoplasm;GO:0031965 nuclear membrane", "go_biological_process": "GO:0010557 positive regulation of macromolecule biosynthetic process;GO:0040029 epigenetic regulation of gene expression;GO:0141166 chromosomal 5-methylcytosine DNA demethylation pathway;GO:0044029 positive regulation of gene expression via chromosomal CpG island demethylation;GO:0006338 chromatin remodeling", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LUQ3-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LSN6-1", "uniprot_id": [ { "id": "F1LSN6_RAT", "url": "https://www.uniprot.org/uniprot/F1LSN6", "type": "external" } ], "mass": 582100.0, "length": 5157, "protein_name": "Hydin, axonemal central pair apparatus protein", "gene_name": "Hydin", "organism": "Rat", "refseq_name": "hydrocephalus-inducing protein homolog isoform X1", "refseq_ac": [ { "id": "XP_038954160", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038954160", "type": "external" } ], "gene_names_uniprotkb": "Hydin", "gene_names_refseq": "Hydin", "protein_names_uniprotkb": "Hydin, axonemal central pair apparatus protein", "protein_names_refseq": "hydrocephalus-inducing protein homolog isoform X1", "tax_id": 10116, "disease": "primary ciliary dyskinesia 5 (Disease Ontology:DOID:0110617); hydrocephalus (Disease Ontology:DOID:10908)", "pathway": " (rno:292017)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:1990716 axonemal central apparatus;GO:0005929 cilium;GO:0036126 sperm flagellum;GO:0005930 axoneme;GO:1990718 axonemal central pair projection", "go_biological_process": "GO:1904158 axonemal central apparatus assembly;GO:0007420 brain development;GO:0021591 ventricular system development;GO:0003341 cilium movement;GO:0002064 epithelial cell development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1LSN6-1", "record_type": "protein", "filter_code": "0000000.0000111.000100.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A7C2-1", "uniprot_id": [ { "id": "A0A8I6A7C2_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A7C2", "type": "external" } ], "mass": 25118.0, "length": 211, "protein_name": "RP9, pre-mRNA splicing factor", "gene_name": "Rp9", "organism": "Rat", "refseq_name": "retinitis pigmentosa 9 protein isoform 1", "refseq_ac": [ { "id": "NP_001388106", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001388106", "type": "external" } ], "gene_names_uniprotkb": "Rp9", "gene_names_refseq": "RGD1559759; 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2.3.2.27; BRAP2; Impedes mitogenic signal propagation; RING-type E3 ubiquitin transferase BRAP2", "protein_names_refseq": "BRCA1-associated protein", "tax_id": 10116, "disease": "", "pathway": " (rno:687346); (R-RNO-5673000); (R-RNO-5675221)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "22673903;37647369", "class_list": "", "function": "BRAP silencing protects against neuronal inflammation, oxidative stress and apoptosis in cerebral ischemia-reperfusion injury by promoting PON1 expression., [RefSeq, PubMed]; Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. 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0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0008284 positive regulation of cell population proliferation;GO:0035556 intracellular signal transduction;GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I5ZSI8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AA24-1", "uniprot_id": [ { "id": "A0A8I6AA24_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AA24", "type": "external" } ], "mass": 73450.0, "length": 743, "protein_name": "Collagen type VIII alpha 1 chain", "gene_name": 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0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": 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actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. 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0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0015293 symporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LZT7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AFZ5-1", "uniprot_id": [ { "id": "A0A8I6AFZ5_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AFZ5", "type": "external" } ], "mass": 27378.0, "length": 238, "protein_name": "Serine/arginine-rich splicing factor 7", "gene_name": "Srsf7", "organism": "Rat", "refseq_name": "serine/arginine-rich splicing factor 7", "refseq_ac": [ { "id": "NP_001034124", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034124", "type": "external" } ], "gene_names_uniprotkb": "Srsf7", "gene_names_refseq": "Sfrs7; Srsf7", "protein_names_uniprotkb": "Serine/arginine-rich splicing factor 7; Splicing factor, arginine/serine-rich 7", "protein_names_refseq": "serine/arginine-rich splicing factor 7; splicing factor, arginine/serine-rich 7, 35kDa", "tax_id": 10116, "disease": "clear cell renal cell carcinoma (Disease Ontology:DOID:4467)", "pathway": " (rno:362687); (R-RNO-159236); (R-RNO-72163); (R-RNO-72165); (R-RNO-72203); (R-RNO-9770562)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, 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"https://www.ncbi.nlm.nih.gov/protein/NP_001099900", "type": "external" } ], "gene_names_uniprotkb": "Mgst2", "gene_names_refseq": "Mgst2", "protein_names_uniprotkb": "Microsomal glutathione S-transferase 2; 1.11.1.-; 2.5.1.18; 4.4.1.20; Glutathione peroxidase MGST2; Leukotriene C4 synthase MGST2; Microsomal GST-2; Microsomal GST-II; Microsomal glutathione S-transferase II", "protein_names_refseq": "microsomal glutathione S-transferase 2", "tax_id": 10116, "disease": "", "pathway": " (rno:295037); (R-RNO-156590); (R-RNO-5423646)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "18461660", "class_list": "", "function": "Catalyzes several different glutathione-dependent reactions. Catalyzes the glutathione-dependent reduction of lipid hydroperoxides, such as 5-HPETE. Has glutathione transferase activity, toward xenobiotic electrophiles, such as 1-chloro-2, 4-dinitrobenzene (CDNB). Catalyzes also the conjugation of leukotriene A4 with reduced glutathione to form leukotriene C4 (LTC4). Involved in oxidative DNA damage induced by ER stress and anticancer agents by activating LTC4 biosynthetic machinery in nonimmune cells., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Liver mGST2 was up-regulated in rat model of fulminant hepatic failure., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.5.1.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.18", "type": "external" }, { "id": "1.11.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.-", "type": "external" }, { "id": "4.4.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:4.4.1.20", "type": "external" }, { "id": "5.3.99.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.99.3", "type": "external" }, { "id": "5.3.99.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.99.2", "type": "external" }, { "id": "5.3.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.-", "type": "external" }, { "id": "1.11.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.12", "type": "external" }, { "id": "1.11.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.9", "type": "external" }, { "id": "5.2.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.2", "type": "external" }, { "id": "1.20.4.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.20.4.2", "type": "external" }, { "id": "1.8.5.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.5.1", "type": "external" }, { "id": "2.5.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.-", "type": "external" } ], "go_molecular_function": "GO:0004364 glutathione transferase activity;GO:0043295 glutathione binding;GO:0004464 leukotriene-C4 synthase activity;GO:0008047 enzyme activator activity;GO:0004602 glutathione peroxidase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0005635 nuclear envelope;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0019370 leukotriene biosynthetic process;GO:0006750 glutathione biosynthetic process;GO:0032496 response to lipopolysaccharide;GO:0046466 membrane lipid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I5ZLK2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A254-1", "uniprot_id": [ { "id": "A0A8I6A254_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A254", "type": "external" } ], "mass": 33652.0, "length": 295, "protein_name": "Large ribosomal subunit protein uL15m", "gene_name": "Mrpl15", "organism": "Rat", "refseq_name": "large ribosomal subunit protein uL15m isoform 1", "refseq_ac": [ { "id": "NP_001385932", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385932", "type": "external" } ], "gene_names_uniprotkb": "Mrpl15", "gene_names_refseq": "Mrpl15", "protein_names_uniprotkb": "Large ribosomal subunit protein uL15m; 39S ribosomal protein L15, mitochondrial", "protein_names_refseq": "39S ribosomal protein L15, mitochondrial; large ribosomal subunit protein uL15m isoform 1; large ribosomal subunit protein uL15m", "tax_id": 10116, "disease": "DiGeorge syndrome (Disease Ontology:DOID:11198)", "pathway": " (R-RNO-5389840); (R-RNO-5419276); (R-RNO-9937383)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0015934 large ribosomal subunit;GO:0005762 mitochondrial large ribosomal subunit;GO:0005739 mitochondrion", "go_biological_process": "GO:0006412 translation;GO:1990830 cellular response to leukemia inhibitory factor", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6A254-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A4C5-1", "uniprot_id": [ { "id": "A0A8I6A4C5_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A4C5", "type": "external" } ], "mass": 78651.0, "length": 694, "protein_name": "Methylenetetrahydrofolate reductase", "gene_name": "Mthfr", "organism": "Rat", "refseq_name": "methylenetetrahydrofolate reductase (NADPH) isoform X2", "refseq_ac": [ { "id": "XP_006239475", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006239475", "type": "external" } ], "gene_names_uniprotkb": "Mthfr", "gene_names_refseq": "Mthfr", "protein_names_uniprotkb": "Methylenetetrahydrofolate reductase; 1.5.1.53", "protein_names_refseq": "methylenetetrahydrofolate reductase (NADPH) isoform X2", "tax_id": 10116, "disease": "inflammatory bowel disease (Disease Ontology:DOID:0050589); diffuse large B-cell lymphoma (Disease Ontology:DOID:0050745); peripheral artery disease (Disease Ontology:DOID:0050830); non-arteritic anterior ischemic optic neuropathy (Disease Ontology:DOID:0050864); oral squamous cell carcinoma (Disease Ontology:DOID:0050866); coarctation of the aorta (Disease Ontology:DOID:0051054); stroke (Disease Ontology:DOID:0051061); dextro-looped transposition of the great arteries (Disease Ontology:DOID:0060770); myeloid neoplasm (Disease Ontology:DOID:0070004); spina bifida (Disease Ontology:DOID:0080016); neural tube defect (Disease Ontology:DOID:0080074); hepatic veno-occlusive disease (Disease Ontology:DOID:0080177); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); graft-versus-host disease (Disease Ontology:DOID:0081267); thrombophilia due to thrombin defect (Disease Ontology:DOID:0111907); migraine with aura (Disease Ontology:DOID:10024); open-angle glaucoma (Disease Ontology:DOID:1067); kidney failure (Disease Ontology:DOID:1074); Kuhnt-Junius degeneration (Disease Ontology:DOID:10873); sickle cell anemia (Disease Ontology:DOID:10923); attention deficit hyperactivity disorder (Disease Ontology:DOID:1094); urinary bladder cancer (Disease Ontology:DOID:11054); Budd-Chiari syndrome (Disease Ontology:DOID:11512); nephrosclerosis (Disease Ontology:DOID:11664); portal vein thrombosis (Disease Ontology:DOID:11695); factor VIII deficiency (Disease Ontology:DOID:12134); male infertility (Disease Ontology:DOID:12336); Graves' disease (Disease Ontology:DOID:12361); cardiovascular system disease (Disease Ontology:DOID:1287); carotid stenosis (Disease Ontology:DOID:13001); angle-closure glaucoma (Disease Ontology:DOID:13550); alcoholic liver cirrhosis (Disease Ontology:DOID:14018); Down syndrome (Disease Ontology:DOID:14250); hypothyroidism (Disease Ontology:DOID:1459); thrombocytopenia (Disease Ontology:DOID:1588); retinal vein occlusion (Disease Ontology:DOID:1727); squamous cell carcinoma (Disease Ontology:DOID:1749); pancreatic cancer (Disease Ontology:DOID:1793); atherosclerosis (Disease Ontology:DOID:1936); rectal benign neoplasm (Disease Ontology:DOID:1984); hepatitis B (Disease Ontology:DOID:2043); nephroblastoma (Disease Ontology:DOID:2154); anemia (Disease Ontology:DOID:2355); renal artery disease (Disease Ontology:DOID:2388); thrombophilia (Disease Ontology:DOID:2452); transitional cell carcinoma (Disease Ontology:DOID:2671); asthma (Disease Ontology:DOID:2841); glomerulonephritis (Disease Ontology:DOID:2921); familial Mediterranean fever (Disease Ontology:DOID:2987); lipid metabolism disorder (Disease Ontology:DOID:3146); ischemia (Disease Ontology:DOID:326); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); osteosarcoma (Disease Ontology:DOID:3347); coronary artery disease (Disease Ontology:DOID:3393); cerebral infarction (Disease Ontology:DOID:3526); cervical cancer (Disease Ontology:DOID:4362); renal cell carcinoma (Disease Ontology:DOID:4450); clear cell renal cell carcinoma (Disease Ontology:DOID:4467); cholangiocarcinoma (Disease Ontology:DOID:4947); liver cirrhosis (Disease Ontology:DOID:5082); lung small cell carcinoma (Disease Ontology:DOID:5409); schizophrenia (Disease Ontology:DOID:5419); eye disease (Disease Ontology:DOID:5614); myocardial infarction (Disease Ontology:DOID:5844); mitral valve disease (Disease Ontology:DOID:61); migraine (Disease Ontology:DOID:6364); tetralogy of Fallot (Disease Ontology:DOID:6419); hepatocellular carcinoma (Disease Ontology:DOID:684); ankylosing spondylitis (Disease Ontology:DOID:7147); rheumatoid arthritis (Disease Ontology:DOID:7148); abdominal aortic aneurysm (Disease Ontology:DOID:7693); end stage renal disease (Disease Ontology:DOID:783); chronic kidney disease (Disease Ontology:DOID:784); hyperthyroidism (Disease Ontology:DOID:7998); cataract (Disease Ontology:DOID:83); chronic myeloid leukemia (Disease Ontology:DOID:8552); smallpox (Disease Ontology:DOID:8736); diabetic retinopathy (Disease Ontology:DOID:8947); acute myeloid leukemia (Disease Ontology:DOID:9119); liver benign neoplasm (Disease Ontology:DOID:916); hyperhomocysteinemia (Disease Ontology:DOID:9279); cleft lip (Disease Ontology:DOID:9296); type 2 diabetes mellitus (Disease Ontology:DOID:9352); hypopituitarism (Disease Ontology:DOID:9406); steatotic liver disease (Disease Ontology:DOID:9452); multiple myeloma (Disease Ontology:DOID:9538); aphthous stomatitis (Disease Ontology:DOID:9663); type 1 diabetes mellitus (Disease Ontology:DOID:9744); Meniere's disease (Disease Ontology:DOID:9849); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (rno:362657); (R-RNO-196757)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a cosubstrate for homocysteine remethylation to methionine. Represents a key regulatory connection between the folate and methionine cycles., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 90, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.5.1.53", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.1.53", "type": "external" } ], "go_molecular_function": "GO:0106313 methylenetetrahydrofolate reductase (NADPH) activity;GO:0050660 flavin adenine dinucleotide binding;GO:0044877 protein-containing complex binding;GO:0004489 methylenetetrahydrofolate reductase [NAD(P)H] activity;GO:0050661 NADP binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0035999 tetrahydrofolate interconversion;GO:0006555 methionine metabolic process;GO:0001666 response to hypoxia;GO:0001843 neural tube closure;GO:0070555 response to interleukin-1", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6A4C5-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZN22-1", "uniprot_id": [ { "id": "A0A8I5ZN22_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZN22", "type": "external" } ], "mass": 61774.0, "length": 574, "protein_name": "E3 ubiquitin-protein ligase NEURL1", "gene_name": "Neurl1", "organism": "Rat", "refseq_name": "E3 ubiquitin-protein ligase NEURL1 isoform 1", "refseq_ac": [ { "id": "NP_001388553", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001388553", "type": "external" } ], "gene_names_uniprotkb": "Neurl1; Neurl1a; Neurl", "gene_names_refseq": "Neurl1a; Neurl1; Neurl", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase NEURL1; 2.3.2.27; Neuralized-like protein 1A; RING-type E3 ubiquitin transferase NEURL1", "protein_names_refseq": "E3 ubiquitin-protein ligase NEURL1 isoform 1; E3 ubiquitin-protein ligase NEURL1; neuralized homolog 1A; neuralized-like homolog; neuralized-like protein 1A", "tax_id": 10116, "disease": "", "pathway": " (rno:309459)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "27780737;31068605", "class_list": "", "function": "Endogenous NEURL1 mRNAs with both longer and shorter 3'UTRs are enriched in the neurites of cultured rat primary hippocampal neurons. Both NEURL1 3'UTRs can mediate transport of reporter mRNAs into dendrites in primary hippocampal neurons., [RefSeq, PubMed]; Neuralized family member NEURL1 is a ubiquitin ligase for the cGMP-specific phosphodiesterase 9A. Publication Status: Online-Only, [RefSeq, PubMed]; Plays a role in hippocampal-dependent synaptic plasticity, learning and memory. Involved in the formation of spines and functional synaptic contacts by modulating the translational activity of the cytoplasmic polyadenylation element-binding protein CPEB3. Promotes ubiquitination of CPEB3, and hence induces CPEB3-dependent mRNA translation activation of glutamate receptor GRIA1 and GRIA2. Can function as an E3 ubiquitin-protein ligase to activate monoubiquitination of JAG1 (in vitro), thereby regulating the Notch pathway. Acts as a tumor suppressor; inhibits malignant cell transformation of medulloblastoma (MB) cells by inhibiting the Notch signaling pathway., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity;GO:0045182 translation regulator activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0014069 postsynaptic density;GO:0030425 dendrite;GO:0043204 perikaryon;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0006417 regulation of translation;GO:0007219 Notch signaling pathway;GO:0023051 regulation of signaling;GO:0010646 regulation of cell communication;GO:0008285 negative regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8I5ZN22-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A0N0-1", "uniprot_id": [ { "id": "A0A8I6A0N0_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A0N0", "type": "external" } ], "mass": 59137.0, "length": 525, "protein_name": "Cytidine and dCMP deaminase domain-containing protein 1", "gene_name": "Cdadc1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Cdadc1", "gene_names_refseq": "", "protein_names_uniprotkb": "Cytidine and dCMP deaminase domain-containing protein 1; 3.5.4.5; Cytidine deaminase", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the deamination of cytidine and deoxycytidine into uridine and deoxyuridine, respectively. May play an important role in testicular development and spermatogenesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.5.4.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.5", "type": "external" } ], "go_molecular_function": "GO:0004126 cytidine deaminase activity;GO:0008270 zinc ion binding;GO:0004132 dCMP deaminase activity;GO:0061676 importin-alpha family protein binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005634 nucleus", "go_biological_process": "GO:0070383 DNA cytosine deamination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6A0N0-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZT44-1", "uniprot_id": [ { "id": "A0A8I5ZT44_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZT44", "type": "external" } ], "mass": 29352.0, "length": 257, "protein_name": "TLC domain containing 3A", "gene_name": "Tlcd3a", "organism": "Rat", "refseq_name": "TLC domain-containing protein 3A", "refseq_ac": [ { "id": "NP_001385940", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385940", "type": "external" } ], "gene_names_uniprotkb": "Tlcd3a", "gene_names_refseq": "Fam57a; RGD1307493; Tlcd3a", "protein_names_uniprotkb": "TLC domain containing 3A", "protein_names_refseq": "TLC domain-containing protein 3A; family with sequence similarity 57, member A; protein FAM57A", "tax_id": 10116, "disease": "chromosome 16p11.2 deletion syndrome, 593-kb (Disease Ontology:DOID:0070515)", "pathway": " (rno:100360533)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane", "go_biological_process": "GO:0055088 lipid homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I5ZT44-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0RBE8-1", "uniprot_id": [ { "id": "M0RBE8_RAT", "url": "https://www.uniprot.org/uniprot/M0RBE8", "type": "external" } ], "mass": 53247.0, "length": 504, "protein_name": "Actin nucleation-promoting factor WAS", "gene_name": "Was", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Was", "gene_names_refseq": "", "protein_names_uniprotkb": "Actin nucleation-promoting factor WAS", "protein_names_refseq": "", "tax_id": 10116, "disease": "X-linked severe congenital neutropenia (Disease Ontology:DOID:0112128); thrombocytopenia (Disease Ontology:DOID:1588); IgA glomerulonephritis (Disease Ontology:DOID:2986); Wiskott-Aldrich syndrome (Disease Ontology:DOID:9169)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Effector protein for Rho-type GTPases that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria. In addition to its role in the cytoplasmic cytoskeleton, also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. Promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0017124 SH3 domain binding;GO:0019901 protein kinase binding;GO:0042802 identical protein binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005856 cytoskeleton;GO:0005829 cytosol;GO:0005884 actin filament;GO:0005911 cell-cell junction", "go_biological_process": "GO:0007015 actin filament organization;GO:0008064 regulation of actin polymerization or depolymerization;GO:0006955 immune response;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0042110 T cell activation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "M0RBE8-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M4W7-1", "uniprot_id": [ { "id": "F1M4W7_RAT", "url": "https://www.uniprot.org/uniprot/F1M4W7", "type": "external" } ], "mass": 82877.0, "length": 717, "protein_name": "Cleavage stimulation factor subunit 3", "gene_name": "Cstf3", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Cstf3", "gene_names_refseq": "", "protein_names_uniprotkb": "Cleavage stimulation factor subunit 3; CF-1 77 kDa subunit; Cleavage stimulation factor 77 kDa subunit", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-73856); (R-RNO-77595); (R-RNO-9770562)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005848 mRNA cleavage stimulating factor complex", "go_biological_process": "GO:0031124 mRNA 3'-end processing;GO:0031123 RNA 3'-end processing;GO:0031440 regulation of mRNA 3'-end processing;GO:0180010 co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1M4W7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1MA92-1", "uniprot_id": [ { "id": "F1MA92_RAT", "url": "https://www.uniprot.org/uniprot/F1MA92", "type": "external" } ], "mass": 61227.0, "length": 536, "protein_name": "Phospholipase D family, member 5", "gene_name": "Pld5", "organism": "Rat", "refseq_name": "inactive phospholipase D5", "refseq_ac": [ { "id": "NP_001178603", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178603", "type": "external" } ], "gene_names_uniprotkb": "Pld5", "gene_names_refseq": "Pld5; RGD1562609", "protein_names_uniprotkb": "Phospholipase D family, member 5", "protein_names_refseq": "inactive phospholipase D5", "tax_id": 10116, "disease": "", "pathway": " (rno:289270)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016788 hydrolase activity, acting on ester bonds", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MA92-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M332-1", "uniprot_id": [ { "id": "F1M332_RAT", "url": "https://www.uniprot.org/uniprot/F1M332", "type": "external" } ], "mass": 90895.0, "length": 812, "protein_name": "Rho GTPase activating protein 28", "gene_name": "Arhgap28", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Arhgap28", "gene_names_refseq": "", "protein_names_uniprotkb": "Rho GTPase activating protein 28", "protein_names_refseq": "", "tax_id": 10116, "disease": "allergic disease (Disease Ontology:DOID:1205); meningioma (Disease Ontology:DOID:3565)", "pathway": " (rno:301709); (R-RNO-8980692)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0007165 signal transduction;GO:0051056 regulation of small GTPase mediated signal transduction;GO:0051497 negative regulation of stress fiber assembly;GO:0030833 regulation of actin filament polymerization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M332-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LR36-1", "uniprot_id": [ { "id": "F1LR36_RAT", "url": "https://www.uniprot.org/uniprot/F1LR36", "type": "external" } ], "mass": 199017.0, "length": 1726, "protein_name": "Transcription elongation factor SPT6", "gene_name": "Supt6h", "organism": "Rat", "refseq_name": "transcription elongation factor SPT6", "refseq_ac": [ { "id": "NP_001178749", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178749", "type": "external" } ], "gene_names_uniprotkb": "Supt6h", "gene_names_refseq": "Supt6h", "protein_names_uniprotkb": "Transcription elongation factor SPT6; Transcription elongation factor spt6", "protein_names_refseq": "transcription elongation factor SPT6", "tax_id": 10116, "disease": "", "pathway": " (rno:303281); (R-RNO-112382); (R-RNO-674695); (R-RNO-75955)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Histone H3-H4 chaperone that plays a key role in the regulation of transcription elongation and mRNA processing. Enhances the transcription elongation by RNA polymerase II (RNAPII) and is also required for the efficient activation of transcriptional elongation by the HIV-1 nuclear transcriptional activator, Tat. Besides chaperoning histones in transcription, acts to transport and splice mRNA by forming a complex with IWS1 and the C-terminal domain (CTD) of the RNAPII subunit RPB1 (POLR2A). The SUPT6H:IWS1:CTD complex recruits mRNA export factors (ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes (such as SETD2), to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription. SUPT6H via its association with SETD1A, regulates both class-switch recombination and somatic hypermutation through formation of H3K4me3 epigenetic marks on activation-induced cytidine deaminase (AICDA) target loci. Promotes the activation of the myogenic gene program by entailing erasure of the repressive H3K27me3 epigenetic mark through stabilization of the chromatin interaction of the H3K27 demethylase KDM6A., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0042393 histone binding;GO:0031491 nucleosome binding", "go_cellular_component": "GO:0008023 transcription elongation factor complex;GO:0005634 nucleus", "go_biological_process": "GO:0034728 nucleosome organization;GO:0006397 mRNA processing;GO:0008380 RNA splicing;GO:0006368 transcription elongation by RNA polymerase II;GO:0051028 mRNA transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1LR36-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R829-1", "uniprot_id": [ { "id": "M0R829_RAT", "url": "https://www.uniprot.org/uniprot/M0R829", "type": "external" } ], "mass": 119435.0, "length": 1038, "protein_name": "Myosin IH", "gene_name": "Myo1h", "organism": "Rat", "refseq_name": "myosin IH", "refseq_ac": [ { "id": "NP_001425342", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001425342", "type": "external" } ], "gene_names_uniprotkb": "Myo1h", "gene_names_refseq": "AABR07036550.1; Myo1h", "protein_names_uniprotkb": "Myosin IH", "protein_names_refseq": "myosin IH; unconventional myosin-Ih-like; unconventional myosin-Ih", "tax_id": 10116, "disease": "congenital central hypoventilation syndrome (Disease Ontology:DOID:0060731)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0005524 ATP binding;GO:0003774 cytoskeletal motor activity;GO:0051015 actin filament binding;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0016459 myosin complex;GO:0098862 cluster of actin-based cell projections;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0015629 actin cytoskeleton", "go_biological_process": "GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0030048 actin filament-based movement", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R829-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LNQ2-1", "uniprot_id": [ { "id": "F1LNQ2_RAT", "url": "https://www.uniprot.org/uniprot/F1LNQ2", "type": "external" } ], "mass": 143008.0, "length": 1300, "protein_name": "Activating molecule in BECN1-regulated autophagy protein 1", "gene_name": "Ambra1", "organism": "Rat", "refseq_name": "activating molecule in BECN1-regulated autophagy protein 1", "refseq_ac": [ { "id": "NP_001127813", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001127813", "type": "external" } ], "gene_names_uniprotkb": "Ambra1", "gene_names_refseq": "Ambra1; Nyw1", "protein_names_uniprotkb": "Activating molecule in BECN1-regulated autophagy protein 1", "protein_names_refseq": "activating molecule in BECN1-regulated autophagy protein 1; autophagy/beclin 1 regulator 1; ischemia related factor NYW-1", "tax_id": 10116, "disease": "multiple system atrophy (Disease Ontology:DOID:4752)", "pathway": " (rno:59319); (R-RNO-1632852)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "25117440;33083461", "class_list": "", "function": "Ambra1 Alleviates Hypoxia/Reoxygenation Injury in H9C2 Cells by Regulating Autophagy and Reactive Oxygen Species. Publication Status: Online-Only, [RefSeq, PubMed]; Ambra1 is a crucial regulator of autophagy and apoptosis through AMPK signaling pathway in cardiomyocytes that maintains the balance between autophagy and apoptosis., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding;GO:0051020 GTPase binding;GO:0019903 protein phosphatase binding;GO:1990756 ubiquitin-like ligase-substrate adaptor activity;GO:0072542 protein phosphatase activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0005856 cytoskeleton", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007399 nervous system development;GO:0030154 cell differentiation;GO:0006914 autophagy;GO:0010508 positive regulation of autophagy", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1LNQ2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M8D7-1", "uniprot_id": [ { "id": "F1M8D7_RAT", "url": "https://www.uniprot.org/uniprot/F1M8D7", "type": "external" } ], "mass": 247873.0, "length": 2221, "protein_name": "Integrator complex subunit 1", "gene_name": "Ints1", "organism": "Rat", "refseq_name": "integrator complex subunit 1 isoform X3", "refseq_ac": [ { "id": "XP_063127803", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063127803", "type": "external" } ], "gene_names_uniprotkb": "Ints1", "gene_names_refseq": "Ints1", "protein_names_uniprotkb": "Integrator complex subunit 1", "protein_names_refseq": "integrator complex subunit 1 isoform X3", "tax_id": 10116, "disease": "neurodevelopmental disorder with cataracts, poor growth, and dysmorphic facies (Disease Ontology:DOID:0070346); cataract (Disease Ontology:DOID:83)", "pathway": " (rno:288514); (R-RNO-6807505)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0032039 integrator complex;GO:0005634 nucleus;GO:0160232 INTAC complex", "go_biological_process": "GO:0034474 U2 snRNA 3'-end processing;GO:0034243 regulation of transcription elongation by RNA polymerase II;GO:0043066 negative regulation of apoptotic process;GO:0007566 embryo implantation;GO:0016180 snRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1M8D7-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LMK2-1", "uniprot_id": [ { "id": "F1LMK2_RAT", "url": "https://www.uniprot.org/uniprot/F1LMK2", "type": "external" } ], "mass": 71602.0, "length": 628, "protein_name": "E3 ubiquitin-protein ligase TRIM41", "gene_name": "Trim41", "organism": "Rat", "refseq_name": "E3 ubiquitin-protein ligase TRIM41", "refseq_ac": [ { "id": "NP_001128209", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001128209", "type": "external" } ], "gene_names_uniprotkb": "Trim41", "gene_names_refseq": "Trim41", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase TRIM41; 2.3.2.27; Tripartite motif-containing protein 41", "protein_names_refseq": "E3 ubiquitin-protein ligase TRIM41; tripartite motif protein 41", "tax_id": 10116, "disease": "", "pathway": " (rno:303088); (R-RNO-983168)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "17893151", "class_list": "", "function": "E3 ligase that plays essential roles in innate antiviral response. Directly binds to influenza A virus or vesicular stomatitis virus nucleoproteins and targets them for ubiquitination and proteasomal degradation, thereby limiting viral infections. Activates the innate antiviral response by catalyzing monoubiquitination of CGAS, thereby activating CGAS. Also involved in innate antiviral response by mediating 'Lys-63'-linked polyubiquitylation of BCL10 which in turn hubs NEMO for activation of NF-kappa-B and IRF3 pathways. Catalyzes the ubiquitin-mediated degradation of other substrates including protein kinase C, ZSCAN21 or TOP3B suggesting additional roles besides its function in immune response., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; RINCK is an E3 ligase that specifically recognizes the C1 domain of PKC isoforms, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "2.3.2.32", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.32", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "2.3.2.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.24", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0001650 fibrillar center", "go_biological_process": "GO:0051607 defense response to virus;GO:0071222 cellular response to lipopolysaccharide;GO:0071225 cellular response to muramyl dipeptide;GO:0060340 positive regulation of type I interferon-mediated signaling pathway;GO:0006513 protein monoubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1LMK2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LN08-1", "uniprot_id": [ { "id": "F1LN08_RAT", "url": "https://www.uniprot.org/uniprot/F1LN08", "type": "external" } ], "mass": 66839.0, "length": 609, "protein_name": "Zinc finger protein 276", "gene_name": "Zfp276", "organism": "Rat", "refseq_name": "zinc finger protein 276", "refseq_ac": [ { "id": "NP_001012058", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012058", "type": "external" } ], "gene_names_uniprotkb": "Zfp276", "gene_names_refseq": "Zfp276", "protein_names_uniprotkb": "Zinc finger protein 276", "protein_names_refseq": "zinc finger protein 276", "tax_id": 10116, "disease": "", "pathway": " (rno:307924)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:1990837 sequence-specific double-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000776 kinetochore", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LN08-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LPW6-1", "uniprot_id": [ { "id": "F1LPW6_RAT", "url": "https://www.uniprot.org/uniprot/F1LPW6", "type": "external" } ], "mass": 36795.0, "length": 320, "protein_name": "Spindlin family member 2B like 1", "gene_name": "Spin2bl1", "organism": "Rat", "refseq_name": "spindlin-2-like", "refseq_ac": [ { "id": "XP_038956194", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038956194", "type": "external" } ], "gene_names_uniprotkb": "Spin2bl1; RGD1565862", "gene_names_refseq": "Spin2bl1", "protein_names_uniprotkb": "Spindlin family member 2B like 1", "protein_names_refseq": "spindlin-2-like", "tax_id": 10116, "disease": "", "pathway": " (rno:302579)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0007276 gamete generation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LPW6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LR42-1", "uniprot_id": [ { "id": "F1LR42_RAT", "url": "https://www.uniprot.org/uniprot/F1LR42", "type": "external" } ], "mass": 80376.0, "length": 711, "protein_name": "RUN and FYVE domain-containing protein 1", "gene_name": "Rufy1", "organism": "Rat", "refseq_name": "RUN and FYVE domain-containing protein 1", "refseq_ac": [ { "id": "NP_001094197", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094197", "type": "external" } ], "gene_names_uniprotkb": "Rufy1", "gene_names_refseq": "Rufy1", "protein_names_uniprotkb": "RUN and FYVE domain-containing protein 1; Rab4-interacting protein", "protein_names_refseq": "RUN and FYVE domain-containing protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:360521); (R-RNO-1660499)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Activating adapter involved in cargo sorting from early/recycling endosomes. Regulates retrieval of proteins from endosomes to the trans-Golgi network through interaction with the dynein-dynactin complex. Dual effector of RAB4B and RAB14, mediates a cooperative interaction allowing endosomal tethering and fusion. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking. In oocytes, self-assembles to form a protein matrix which hold together endolysosomes, autophagosomes and proteasomes and generate non-membrane-bound compartments called endo-lysosomal vesicular assemblies (ELVAs). In immature oocytes, ELVAs sequester ubiquitinated protein aggregates and degrade them upon oocyte maturation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0017124 SH3 domain binding;GO:0030674 protein-macromolecule adaptor activity;GO:0042802 identical protein binding;GO:0008289 lipid binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005768 endosome;GO:0005829 cytosol;GO:0031901 early endosome membrane", "go_biological_process": "GO:0006897 endocytosis;GO:0015031 protein transport;GO:0030100 regulation of endocytosis;GO:0007264 small GTPase-mediated signal transduction;GO:0034058 endosomal vesicle fusion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LR42-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LR51-1", "uniprot_id": [ { "id": "F1LR51_RAT", "url": "https://www.uniprot.org/uniprot/F1LR51", "type": "external" } ], "mass": 69209.0, "length": 642, "protein_name": "Myb/SANT DNA binding domain containing 2", "gene_name": "Msantd2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Msantd2", "gene_names_refseq": "", "protein_names_uniprotkb": "Myb/SANT DNA binding domain containing 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0016604 nuclear body", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LR51-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M3J4-1", "uniprot_id": [ { "id": "MRP4_RAT", "url": "https://www.uniprot.org/uniprot/F1M3J4", "type": "external" } ], "mass": 148904.0, "length": 1325, "protein_name": "ATP-binding cassette subfamily C member 4", "gene_name": "Abcc4", "organism": "Rat", "refseq_name": "ATP-binding cassette subfamily C member 4", "refseq_ac": [ { "id": "NP_596902", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_596902", "type": "external" } ], "gene_names_uniprotkb": "Abcc4; Mrp4", "gene_names_refseq": "Abcc4; Mrp4; RGD1565953", "protein_names_uniprotkb": "ATP-binding cassette subfamily C member 4; 7.6.2.-; 7.6.2.2; 7.6.2.3; Multidrug resistance-associated protein 4", "protein_names_refseq": "ABC-tranporter; ATP-binding cassette protein C4; ATP-binding cassette subfamily C member 4; ATP-binding cassette, sub-family C (CFTR/MRP), member 4; ATP-binding cassette, subfamily C (CFTR/MRP), member 4; multidrug resistance-associated protein 4", "tax_id": 10116, "disease": "cholestasis (Disease Ontology:DOID:13580); extrahepatic cholestasis (Disease Ontology:DOID:13619); cystic fibrosis (Disease Ontology:DOID:1485); primary ovarian insufficiency (Disease Ontology:DOID:5426)", "pathway": " (rno:170924); (R-RNO-114608); (R-RNO-382556); (R-RNO-9748787); (R-RNO-9753281)", "pathway_count": 5, "publication_count": 7, "publication_id_list": "12883481;15030973;15047146;22673903;30995593;33132311;35269592", "class_list": "", "function": "ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds and xenobiotics from cells (By similarity). Transports a range of endogenous molecules that have a key role in cellular communication and signaling, including cyclic nucleotides such as cyclic AMP (cAMP) and cyclic GMP (cGMP), bile acids, steroid conjugates, urate, and prostaglandins (By similarity). Mediates the ATP-dependent efflux of glutathione conjugates such as leukotriene C4 (LTC4) and leukotriene B4 (LTB4) too. The presence of GSH is necessary for the ATP-dependent transport of LTB4, whereas GSH is not required for the transport of LTC4 (By similarity). Mediates the cotransport of bile acids with reduced glutathione (GSH) (By similarity). Transports a wide range of drugs and their metabolites, including anticancer, antiviral and antibiotic molecules (By similarity). Confers resistance to anticancer agents such as methotrexate (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Inflammation-Induced Attenuation of Prostaglandin D2 Elimination across Rat Blood-Brain Barrier: Involvement of the Downregulation of Organic Anion Transporter 3 and Multidrug Resistance-Associated Protein 4., [RefSeq, PubMed]; MRP4 can mediate the efflux of reduced glutatione from hepatocytes into blood by cotransport with monoanionic bile salts., [RefSeq, PubMed]; Obstructive cholestasis results in progressive up-regulation of Mrp4 protein in liver but down-regulation in kidney. The absence of corresponding changes in Mrp4 mRNA suggests posttranscriptional mechanisms as predominant regulators of Mrp4 expression., [RefSeq, PubMed]; The Daily Expression of ABCC4 at the BCSFB Affects the Transport of Its Substrate Methotrexate. Publication Status: Online-Only, [RefSeq, PubMed]; These data suggest that inhibition of MRP4 significantly alleviates sepsis-induced acute lung injury in rats. Erratum:[Int Immunopharmacol. 2023 Sep;122:110699. doi: 10.1016/j.intimp.2023.110699. PMID: 37500384], [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6QMG6", "ec_number_list": [ { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "7.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.9.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.9.1.1", "type": "external" }, { "id": "6.1.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.12", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "1.11.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.-", "type": "external" }, { "id": "1.8.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.-.-", "type": "external" }, { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" }, { "id": "1.8.5.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.5.1", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" } ], "go_molecular_function": "GO:0042910 xenobiotic transmembrane transporter activity;GO:0005524 ATP binding;GO:0022857 transmembrane transporter activity;GO:0042626 ATPase-coupled transmembrane transporter activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane;GO:0031088 platelet dense granule membrane", "go_biological_process": "GO:0055085 transmembrane transport;GO:0015721 bile acid and bile salt transport;GO:0048661 positive regulation of smooth muscle cell proliferation;GO:0060271 cilium assembly;GO:0009410 response to xenobiotic stimulus", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "F1M3J4-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LRS5-1", "uniprot_id": [ { "id": "F1LRS5_RAT", "url": "https://www.uniprot.org/uniprot/F1LRS5", "type": "external" } ], "mass": 72534.0, "length": 652, "protein_name": "Amyloid beta precursor like protein 1", "gene_name": "Aplp1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Aplp1", "gene_names_refseq": "", "protein_names_uniprotkb": "Amyloid beta precursor like protein 1; Amyloid beta (A4) precursor-like protein 1; Amyloid-like protein 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "Alzheimer's disease 1 (Disease Ontology:DOID:0080348); Alzheimer's disease (Disease Ontology:DOID:10652)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding. Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I., [UniProtKB, UniProtKB]; The gamma-CTF peptide, C30, is a potent enhancer of neuronal apoptosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008201 heparin binding;GO:0042802 identical protein binding;GO:0046914 transition metal ion binding;GO:0031694 alpha-2A adrenergic receptor binding;GO:0031696 alpha-2C adrenergic receptor binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0006417 regulation of translation;GO:0030198 extracellular matrix organization;GO:0030900 forebrain development;GO:0071874 cellular response to norepinephrine stimulus;GO:0106072 negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LRS5-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LRV5-1", "uniprot_id": [ { "id": "F1LRV5_RAT", "url": "https://www.uniprot.org/uniprot/F1LRV5", "type": "external" } ], "mass": 58541.0, "length": 524, "protein_name": "Butyrophilin, subfamily 1, member A1", "gene_name": "Btn1a1", "organism": "Rat", "refseq_name": "butyrophilin subfamily 1 member A1 precursor", "refseq_ac": [ { "id": "NP_001163808", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163808", "type": "external" } ], "gene_names_uniprotkb": "Btn1a1", "gene_names_refseq": "Btn1a1", "protein_names_uniprotkb": "Butyrophilin, subfamily 1, member A1", "protein_names_refseq": "butyrophilin subfamily 1 member A1 precursor", "tax_id": 10116, "disease": "", "pathway": " (rno:306956); (R-RNO-8851680)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding", "go_cellular_component": "GO:0009897 external side of plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0050852 T cell receptor signaling pathway;GO:0001817 regulation of cytokine production", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LRV5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LSL7-1", "uniprot_id": [ { "id": "F1LSL7_RAT", "url": "https://www.uniprot.org/uniprot/F1LSL7", "type": "external" } ], "mass": 49444.0, "length": 443, "protein_name": "KLF transcription factor 5", "gene_name": "Klf5", 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interaction of klf5 with c-Myc Publication Status: Online-Only, [RefSeq, PubMed]; Inhibiting Intestinal Kruppel-Like Factor 5 Impairs the Beneficial Role of Renal Denervation in Gut Microbiota in Rats with Heart Failure., [RefSeq, PubMed]; MiR-448-3p affects macrophage infiltration during intracranial aneurysm formation by regulating KLF5 expression., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, 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"reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LWV6-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LWZ3-1", "uniprot_id": [ { "id": "F1LWZ3_RAT", "url": "https://www.uniprot.org/uniprot/F1LWZ3", "type": "external" } ], "mass": 93257.0, "length": 825, "protein_name": "Inactive rhomboid protein", "gene_name": "Rhbdf2", "organism": "Rat", "refseq_name": "inactive rhomboid protein 2", "refseq_ac": [ { "id": "NP_001100537", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100537", "type": "external" } ], "gene_names_uniprotkb": "Rhbdf2", "gene_names_refseq": "Rhbdf2; Rhbdl6", "protein_names_uniprotkb": "Inactive rhomboid protein; Rhomboid family member; Rhomboid veinlet-like protein; iRhom", "protein_names_refseq": "inactive rhomboid protein 2; rhomboid family member 2; rhomboid, veinlet-like 6", "tax_id": 10116, "disease": "palmoplantar keratoderma-esophageal carcinoma syndrome (Disease Ontology:DOID:0111506)", "pathway": " (rno:303690)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "22673903;29393594", "class_list": "", "function": "Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0050709 negative regulation of protein secretion;GO:0072659 protein localization to plasma membrane;GO:0050708 regulation of protein secretion;GO:0042058 regulation of epidermal growth factor receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1LWZ3-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LWZ7-1", "uniprot_id": [ { "id": "F1LWZ7_RAT", "url": "https://www.uniprot.org/uniprot/F1LWZ7", "type": "external" } ], "mass": 131619.0, "length": 1150, "protein_name": "TBC1 domain family member 8", "gene_name": "Tbc1d8", "organism": "Rat", "refseq_name": "TBC1 domain family member 8 isoform X1", "refseq_ac": [ { "id": "XP_006244913", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006244913", "type": "external" } ], "gene_names_uniprotkb": "Tbc1d8", "gene_names_refseq": "IHoP; Tbc1d8", "protein_names_uniprotkb": "TBC1 domain family member 8; Vascular Rab-GAP/TBC-containing protein", "protein_names_refseq": "TBC1 domain family member 8 isoform X1", "tax_id": 10116, "disease": "nephrotic syndrome type 20 (Disease Ontology:DOID:0070357)", "pathway": " (rno:680133)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May act as a GTPase-activating protein for Rab family protein(s)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005509 calcium ion binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LWZ7-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LXD8-1", "uniprot_id": [ { "id": "F1LXD8_RAT", "url": "https://www.uniprot.org/uniprot/F1LXD8", "type": "external" } ], "mass": 117094.0, "length": 1075, "protein_name": "EMILIN-2", "gene_name": "Emilin2", "organism": "Rat", "refseq_name": "EMILIN-2 precursor", "refseq_ac": [ { "id": "NP_001418209", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001418209", "type": "external" } ], "gene_names_uniprotkb": "Emilin2", "gene_names_refseq": "Emilin2", "protein_names_uniprotkb": "EMILIN-2; Elastin microfibril interface-located protein 2", "protein_names_refseq": "EMILIN-2 precursor; EMILIN-2", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-2129379)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0007155 cell adhesion;GO:0043065 positive regulation of apoptotic process;GO:0030336 negative regulation of cell migration;GO:0045766 positive regulation of angiogenesis;GO:0030194 positive regulation of blood coagulation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LXD8-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LXF1-1", "uniprot_id": [ { "id": "BCR_RAT", "url": "https://www.uniprot.org/uniprot/F1LXF1", "type": "external" } ], "mass": 143034.0, "length": 1270, "protein_name": "Breakpoint cluster region protein", "gene_name": "Bcr", "organism": "Rat", "refseq_name": "breakpoint cluster region protein", "refseq_ac": [ { "id": "NP_001406538", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001406538", "type": "external" } ], "gene_names_uniprotkb": "Bcr", "gene_names_refseq": "Bcr", "protein_names_uniprotkb": "Breakpoint cluster region protein; 2.7.11.1", "protein_names_refseq": "BCR, RhoGEF and GTPase activating protein; breakpoint cluster region homolog; breakpoint cluster region protein", "tax_id": 10116, "disease": "leukemia (Disease Ontology:DOID:1240); chronic myeloid leukemia (Disease Ontology:DOID:8552); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (rno:309696); (R-RNO-8980692); (R-RNO-9013026); (R-RNO-9013106); (R-RNO-9013148); (R-RNO-9013149); (R-RNO-9013404); (R-RNO-9013423)", "pathway_count": 8, "publication_count": 4, "publication_id_list": "20962234;22673903;25331951;29046349", "class_list": "", "function": "Data indicate that Src homology 2 domain containing protein 5 (SH2D5) controls neuronal morphology via breakpoint cluster region protein BCR and Rac1 GTP binding protein., [RefSeq, PubMed]; Protein with a unique structure having two opposing regulatory activities toward small GTP-binding proteins. The C-terminus is a GTPase-activating protein (GAP) domain which stimulates GTP hydrolysis by RAC1, RAC2 and CDC42. Accelerates the intrinsic rate of GTP hydrolysis of RAC1 or CDC42, leading to down-regulation of the active GTP-bound form. The central Dbl homology (DH) domain functions as guanine nucleotide exchange factor (GEF) that modulates the GTPases CDC42, RHOA and RAC1. Promotes the conversion of CDC42, RHOA and RAC1 from the GDP-bound to the GTP-bound form. The amino terminus contains an intrinsic kinase activity (By similarity). Functions as an important negative regulator of neuronal RAC1 activity (By similarity). Regulates macrophage functions such as CSF1-directed motility and phagocytosis through the modulation of RAC1 activity. Plays a major role as a RHOA GEF in keratinocytes being involved in focal adhesion formation and keratinocyte differentiation (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; This work identifies BCR as a critical player in Rac1 regulation during oxygen and glucose deprivation in hippocampal neurons., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 16, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.34", "type": "external" }, { "id": "3.1.3.86", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.86", "type": "external" }, { "id": "3.1.3.56", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.56", "type": "external" }, { "id": "3.1.3.36", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.36", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.11.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.19", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "3.1.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.-", "type": "external" }, { "id": "7.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.-", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.7.11.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.4", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.4.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.18", "type": "external" }, { "id": "3.1.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.24.-", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005096 GTPase activator activity;GO:0005524 ATP binding;GO:0019899 enzyme binding;GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0014069 postsynaptic density;GO:0016020 membrane", "go_biological_process": "GO:0032496 response to lipopolysaccharide;GO:0042472 inner ear morphogenesis;GO:0050885 neuromuscular process controlling balance;GO:0030336 negative regulation of cell migration;GO:0050728 negative regulation of inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "F1LXF1-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LXQ1-1", "uniprot_id": [ { "id": "F1LXQ1_RAT", "url": "https://www.uniprot.org/uniprot/F1LXQ1", "type": "external" } ], "mass": 79686.0, "length": 710, "protein_name": "F-box protein 40", "gene_name": "Fbxo40", "organism": "Rat", "refseq_name": "F-box only protein 40", "refseq_ac": [ { "id": "NP_001414377", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414377", "type": "external" } ], "gene_names_uniprotkb": "Fbxo40", "gene_names_refseq": "Fbxo40", "protein_names_uniprotkb": "F-box protein 40", "protein_names_refseq": "F-box only protein 40", "tax_id": 10116, "disease": "", "pathway": " (rno:363790); (R-RNO-8951664); (R-RNO-983168)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "17928169", "class_list": "", "function": "FBXO40 may function as a regulator involved in the postnatal myogenesis., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, 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"0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LYU9-1", "uniprot_id": [ { "id": "F1LYU9_RAT", "url": "https://www.uniprot.org/uniprot/F1LYU9", "type": "external" } ], "mass": 32180.0, "length": 285, "protein_name": "CD209f molecule like 1", "gene_name": "Cd209fl1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Cd209fl1; LOC100363064", "gene_names_refseq": "", "protein_names_uniprotkb": "CD209f molecule like 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, 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"binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LYW9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LYX9-1", "uniprot_id": [ { "id": "F1LYX9_RAT", "url": "https://www.uniprot.org/uniprot/F1LYX9", "type": "external" } ], "mass": 122290.0, "length": 1128, "protein_name": "Desmoglein 2", "gene_name": "Dsg2", "organism": "Rat", "refseq_name": "desmoglein-2 precursor", "refseq_ac": [ { "id": "NP_001414207", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414207", "type": "external" } ], "gene_names_uniprotkb": "Dsg2", "gene_names_refseq": "Dsg2", "protein_names_uniprotkb": "Desmoglein 2", "protein_names_refseq": "desmoglein-2 precursor", "tax_id": 10116, "disease": "arrhythmogenic right 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"go_biological_process": "GO:1903672 positive regulation of sprouting angiogenesis;GO:1902459 positive regulation of stem cell population maintenance;GO:0007155 cell adhesion;GO:0043066 negative regulation of apoptotic process;GO:0045785 positive regulation of cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1LYX9-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M098-1", "uniprot_id": [ { "id": "F1M098_RAT", "url": "https://www.uniprot.org/uniprot/F1M098", "type": "external" } ], "mass": 26944.0, "length": 239, "protein_name": "Ciliary microtubule inner protein 3", "gene_name": "Cimip3", "organism": "Rat", "refseq_name": "putative uncharacterized protein CIMIP3 isoform 5", "refseq_ac": [ { "id": "NP_001404712", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001404712", "type": "external" } ], "gene_names_uniprotkb": "Cimip3; LOC100912849", "gene_names_refseq": "Cimip3; Guca1anb", "protein_names_uniprotkb": "Ciliary microtubule inner protein 3", "protein_names_refseq": "Guca1a neighbor; putative uncharacterized protein CIMIP3 isoform 5", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, 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"protein_name": "N-fatty-acyl-amino acid synthase/hydrolase PM20D1", "gene_name": "Pm20d1", "organism": "Rat", "refseq_name": "N-fatty-acyl-amino acid synthase/hydrolase PM20D1 precursor", "refseq_ac": [ { "id": "NP_001102538", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102538", "type": "external" } ], "gene_names_uniprotkb": "Pm20d1", "gene_names_refseq": "Pm20d1; RGD1564063", "protein_names_uniprotkb": "N-fatty-acyl-amino acid synthase/hydrolase PM20D1; 3.5.1.114; 3.5.1.14; Peptidase M20 domain-containing protein 1", "protein_names_refseq": "N-fatty-acyl-amino acid synthase/hydrolase PM20D1 precursor; N-fatty-acyl-amino acid synthase/hydrolase PM20D1; probable carboxypeptidase PM20D1", "tax_id": 10116, "disease": "", "pathway": " (rno:498226); (R-RNO-9673163)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Secreted enzyme that regulates the endogenous N-fatty acyl amino acid (NAAs) tissue and circulating levels by functioning as a bidirectional NAA synthase/hydrolase. It condenses free fatty acids and free amino acids to generate NAAs and bidirectionally catalyzes the reverse hydrolysis reaction. Some of these NAAs stimulate oxidative metabolism via mitochondrial uncoupling, increasing energy expenditure in a UPC1-independent manner. Thereby, this secreted protein may indirectly regulate whole body energy expenditure. 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SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Mutations of the SLIT2-ROBO2 pathway genes SLIT2 and SRGAP1 confer risk for congenital anomalies of the kidney and urinary tract, [RefSeq, PubMed]; Results suggest that srGAPs are not only involved in the regulation of the Slit-Robo signal transduction, but also in neuronal development and that the translocation of srGAPs is important for their functions, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, 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Or52b1; ratchr1-163166306-163165362_ORF", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 201; olfactory receptor Olr201; olfactory receptor gene Olr201", "tax_id": 10116, "disease": "", "pathway": " (rno:293342)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M5N0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M5Q3-1", "uniprot_id": [ { "id": "F1M5Q3_RAT", "url": "https://www.uniprot.org/uniprot/F1M5Q3", "type": "external" } ], "mass": 28608.0, "length": 263, "protein_name": "Potassium channel tetramerization domain containing 2", "gene_name": "Kctd2", "organism": "Rat", "refseq_name": "BTB/POZ domain-containing protein KCTD2", "refseq_ac": [ { "id": "NP_001414582", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414582", "type": "external" } ], "gene_names_uniprotkb": "Kctd2", "gene_names_refseq": "Kctd2; 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Akd2; RGD1559879", "gene_names_refseq": "Ak9; Akd2; RGD1559879; RGD1560386", "protein_names_uniprotkb": "Adenylate kinase 9; 2.7.4.4; 2.7.4.6", "protein_names_refseq": "adenylate kinase 9; adenylate kinase domain containing 2", "tax_id": 10116, "disease": "spermatogenic failure 89 (Disease Ontology:DOID:0070588); normal pressure hydrocephalus (Disease Ontology:DOID:1572)", "pathway": " (R-RNO-499943)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Broad-specificity nucleoside phosphate kinase involved in cellular nucleotide homeostasis by catalyzing nucleoside-phosphate interconversions. Similar to other adenylate kinases, preferentially catalyzes the phosphorylation of the nucleoside monophosphate AMP with ATP as phosphate donor to produce ADP. In vitro, can also catalyze the phosphorylation of CMP, dAMP and dCMP and use GTP as an alternate phosphate donor. Moreover, exhibits a diphosphate kinase activity, producing ATP, CTP, GTP, UTP, TTP, dATP, dCTP and dGTP from the corresponding diphosphate substrates with either ATP or GTP as phosphate donors. For this activity shows the following substrate preference CDP > UDP > ADP > TDP., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, 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"https://www.rhea-db.org/rhea/?query=ec:3.2.2.6", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" }, { "id": "3.2.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.20", "type": "external" }, { "id": "2.3.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.20", "type": "external" }, { "id": "2.3.1.76", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.76", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0005789 endoplasmic reticulum membrane;GO:0031901 early endosome membrane", "go_biological_process": "GO:0016192 vesicle-mediated transport;GO:0002553 histamine secretion by mast cell;GO:0043303 mast cell degranulation;GO:0097279 histamine secretion mediated by IgE immunoglobulin", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M8M0-1", 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"length": 1615, "protein_name": "Low-density lipoprotein receptor-related protein", "gene_name": "Lrp5", "organism": "Rat", "refseq_name": "low-density lipoprotein receptor-related protein 5 isoform 1 precursor", "refseq_ac": [ { "id": "NP_001424443", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001424443", "type": "external" } ], "gene_names_uniprotkb": "Lrp5", "gene_names_refseq": "Lrp5", "protein_names_uniprotkb": "Low-density lipoprotein receptor-related protein", "protein_names_refseq": "low-density lipoprotein receptor-related protein 5 isoform 1 precursor; low-density lipoprotein receptor-related protein 5", "tax_id": 10116, "disease": "exudative vitreoretinopathy (Disease Ontology:DOID:0050535); nonsyndromic deafness (Disease Ontology:DOID:0050563); osteoporosis-pseudoglioma syndrome (Disease Ontology:DOID:0060849); polycystic liver disease 4 (Disease Ontology:DOID:0060977); polycystic liver disease 1 (Disease Ontology:DOID:0060980); Worth syndrome (Disease Ontology:DOID:0080037); autosomal dominant osteopetrosis 1 (Disease Ontology:DOID:0110937); exudative vitreoretinopathy 4 (Disease Ontology:DOID:0111411); osteonecrosis (Disease Ontology:DOID:10159); microphthalmia (Disease Ontology:DOID:10629); osteoporosis (Disease Ontology:DOID:11476); idiopathic juvenile osteoporosis (Disease Ontology:DOID:12559); heart valve disease (Disease Ontology:DOID:4079); autosomal dominant polycystic kidney disease (Disease Ontology:DOID:898); tendinitis (Disease Ontology:DOID:971); neovascular inflammatory vitreoretinopathy (Disease Ontology:DOID:9719)", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "32833527;34205318;35139333", "class_list": "", "function": "Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes., [UniProtKB, UniProtKB]; LRP5 Regulates HIF-1alpha Stability via Interaction with PHD2 in Ischemic Myocardium. Publication Status: Online-Only, [RefSeq, PubMed]; Low-Density Lipoprotein Receptor-Related Protein 5-Deficient Rats Have Reduced Bone Mass and Abnormal Development of the Retinal Vasculature., [RefSeq, PubMed]; Structure and function of the retina of low-density lipoprotein receptor-related protein 5 (Lrp5)-deficient rats., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 16, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015026 coreceptor activity;GO:0017147 Wnt-protein binding;GO:0042813 Wnt receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0060603 mammary gland duct morphogenesis;GO:0060042 retina morphogenesis in camera-type eye;GO:0060856 establishment of blood-brain barrier;GO:0006897 endocytosis;GO:0007267 cell-cell signaling", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "F1MAD0-1", "record_type": "protein", "filter_code": "0000000.0000110.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1MAG8-1", "uniprot_id": [ { "id": "F1MAG8_RAT", "url": "https://www.uniprot.org/uniprot/F1MAG8", "type": "external" } ], "mass": 89532.0, "length": 777, "protein_name": "Semaphorin 3D", "gene_name": "Sema3d", "organism": "Rat", "refseq_name": "semaphorin-3D", "refseq_ac": [ { "id": "NP_001098103", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001098103", "type": "external" } ], "gene_names_uniprotkb": "Sema3d", "gene_names_refseq": "Sema3d", "protein_names_uniprotkb": "Semaphorin 3D", "protein_names_refseq": "sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D; semaphorin, homolog of the avian Sema3D; semaphorin-3D", "tax_id": 10116, "disease": "childhood-onset asthma (Disease Ontology:DOID:0080815)", "pathway": " (rno:246262)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "19345252;19429098", "class_list": "", "function": "Gene regulation, via an alternative splicing mechanism, affects not only the tissue-specificity of Sema 3D expression, but also the distance over which it can act., [RefSeq, PubMed]; Sema3D may regulate the axonal navigation of the large diameter DRG neurons., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030215 semaphorin receptor binding;GO:0038191 neuropilin binding;GO:0045499 chemorepellent activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane", "go_biological_process": "GO:0030335 positive regulation of cell migration;GO:0071526 semaphorin-plexin signaling pathway;GO:0001755 neural crest cell migration;GO:0050919 negative chemotaxis;GO:0007411 axon guidance", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1MAG8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1MAJ8-1", "uniprot_id": [ { "id": "F1MAJ8_RAT", "url": "https://www.uniprot.org/uniprot/F1MAJ8", "type": "external" } ], "mass": 63194.0, "length": 568, "protein_name": "E3 ubiquitin-protein ligase ZFP91", "gene_name": "Zfp91", "organism": "Rat", "refseq_name": "E3 ubiquitin-protein ligase ZFP91", "refseq_ac": [ { "id": "NP_001162591", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162591", "type": "external" } ], "gene_names_uniprotkb": "Zfp91", "gene_names_refseq": "Zfp91", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase ZFP91; 2.3.2.27; RING-type E3 ubiquitin transferase ZFP91; Zinc finger protein 91 homolog", "protein_names_refseq": "E3 ubiquitin-protein ligase ZFP91; cocaine attenuated zinc-finger protein", "tax_id": 10116, "disease": "stomach cancer (Disease Ontology:DOID:10534); acute myeloid leukemia (Disease Ontology:DOID:9119)", "pathway": " (rno:246282)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "DNA-binding transcription factor. Also acts as an atypical E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked ubiquitination of MAP3K14/NIK, leading to stabilize and activate MAP3K14/NIK. It thereby acts as an activator of the non-canonical NF-kappa-B2/NFKB2 pathway. May also play an important role in cell proliferation and/or anti-apoptosis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0070534 protein K63-linked ubiquitination;GO:0007250 activation of NF-kappaB-inducing kinase activity", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1MAJ8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1MAK1-1", "uniprot_id": [ { "id": "F1MAK1_RAT", "url": "https://www.uniprot.org/uniprot/F1MAK1", "type": "external" } ], "mass": 113087.0, "length": 1048, "protein_name": "Formin-binding protein 4", "gene_name": "Fnbp4", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Fnbp4", "gene_names_refseq": "", "protein_names_uniprotkb": "Formin-binding protein 4; Formin-binding protein 30", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "16641100;22673903", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005654 nucleoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1MAK1-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1MAK4-1", "uniprot_id": [ { "id": "F1MAK4_RAT", "url": "https://www.uniprot.org/uniprot/F1MAK4", "type": "external" } ], "mass": 36687.0, "length": 319, "protein_name": "G protein-coupled receptor 55", "gene_name": "Gpr55", "organism": "Rat", "refseq_name": "G-protein coupled receptor 55", "refseq_ac": [ { "id": "NP_001414365", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414365", "type": "external" } ], "gene_names_uniprotkb": "Gpr55", "gene_names_refseq": "Gpr55", "protein_names_uniprotkb": "G protein-coupled receptor 55", "protein_names_refseq": "G-protein coupled receptor 55", "tax_id": 10116, "disease": "", "pathway": " (rno:501177); (R-RNO-373076); (R-RNO-418594)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "21497900;32967746;35612493;35831708;36099968;38374108", "class_list": "", "function": "Contribution of G Protein-Coupled Receptor 55 to Periaqueductal Gray-Mediated Antinociception in the Inflammatory Pain., [RefSeq, PubMed]; GPR55 activation prevents amphetamine-induced conditioned place preference and decrease the amphetamine-stimulated inflammatory response in the ventral hippocampus in male rats., [RefSeq, PubMed]; GPR55 is expressed in glutamate neurons and functionally modulates drug taking and seeking in rats and mice. Publication Status: Online-Only, [RefSeq, PubMed]; Presynaptic nigral GPR55 receptors stimulate [(3) H]-GABA release through [(3) H]-cAMP production and PKA activation and promote motor behavior., [RefSeq, PubMed]; Prominent expression of GPR55 in decidual cells suggests a role in mediating cannabinoid signalling during fetoplacental development, [RefSeq, PubMed]; The effect of intra-striatal administration of GPR55 agonist (LPI) and antagonist (ML193) on sensorimotor and motor functions in a Parkinson's disease rat model., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004949 cannabinoid receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0045453 bone resorption;GO:0035025 positive regulation of Rho protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "F1MAK4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1MAL8-1", "uniprot_id": [ { "id": "F1MAL8_RAT", "url": "https://www.uniprot.org/uniprot/F1MAL8", "type": "external" } ], "mass": 140958.0, "length": 1286, "protein_name": "HMG-box containing 3", "gene_name": "Hmgxb3", "organism": "Rat", "refseq_name": "HMG domain-containing protein 3", "refseq_ac": [ { "id": "NP_001414191", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414191", "type": "external" } ], "gene_names_uniprotkb": "Hmgxb3", "gene_names_refseq": "Hmgxb3", "protein_names_uniprotkb": "HMG-box containing 3", "protein_names_refseq": "HMG box domain containing 3; HMG domain-containing protein 3", "tax_id": 10116, "disease": "", "pathway": " (rno:361335)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MAL8-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1MAM5-1", "uniprot_id": [ { "id": "F1MAM5_RAT", "url": "https://www.uniprot.org/uniprot/F1MAM5", "type": "external" } ], "mass": 82933.0, "length": 727, "protein_name": "Zinc finger protein 719", "gene_name": "Zfp719", "organism": "Rat", "refseq_name": "zinc finger protein 484-like", "refseq_ac": [ { "id": "NP_001406937", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001406937", "type": "external" } ], "gene_names_uniprotkb": "Zfp719; LOC100361791; LOC102556967", "gene_names_refseq": "Zfp719", "protein_names_uniprotkb": "Zinc finger protein 719", "protein_names_refseq": "rCG53928-like; zinc finger protein 175; zinc finger protein 260; zinc finger protein 484-like; zinc finger protein 883", "tax_id": 10116, "disease": "", "pathway": " (rno:102556967); (R-RNO-212436); (R-RNO-9843940)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005730 nucleolus;GO:0005829 cytosol", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MAM5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F2Z3R5-1", "uniprot_id": [ { "id": "F2Z3R5_RAT", "url": "https://www.uniprot.org/uniprot/F2Z3R5", "type": "external" } ], "mass": 90503.0, "length": 818, "protein_name": "Protocadherin beta-1", "gene_name": "Pcdhb1", "organism": "Rat", "refseq_name": "protocadherin beta-1 precursor", "refseq_ac": [ { "id": "NP_001014800", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014800", "type": "external" } ], "gene_names_uniprotkb": "Pcdhb1", "gene_names_refseq": "Pcdhb1", "protein_names_uniprotkb": "Protocadherin beta-1", "protein_names_refseq": "protocadherin beta-1 precursor", "tax_id": 10116, "disease": "", "pathway": " (rno:364841)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0050839 cell adhesion molecule binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007155 cell adhesion;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F2Z3R5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F7EV11-1", "uniprot_id": [ { "id": "F7EV11_RAT", "url": "https://www.uniprot.org/uniprot/F7EV11", "type": "external" } ], "mass": 55897.0, "length": 511, "protein_name": "Sperm associated antigen 8", "gene_name": "Spag8", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Spag8", "gene_names_refseq": "", "protein_names_uniprotkb": "Sperm associated antigen 8", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:362508)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005929 cilium;GO:0036126 sperm flagellum;GO:0005879 axonemal microtubule", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0030317 flagellated sperm motility", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F7EV11-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F7EXD0-1", "uniprot_id": [ { "id": "F7EXD0_RAT", "url": "https://www.uniprot.org/uniprot/F7EXD0", "type": "external" } ], "mass": 64843.0, "length": 559, "protein_name": "DET1 partner of COP1 E3 ubiquitin ligase", "gene_name": "Det1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Det1", "gene_names_refseq": "", "protein_names_uniprotkb": "DET1 partner of COP1 E3 ubiquitin ligase", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-983168)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding;GO:1990756 ubiquitin-like ligase-substrate adaptor activity;GO:0044877 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Chsy3; RGD1560819", "protein_names_uniprotkb": "Hexosyltransferase; 2.4.1.-", "protein_names_refseq": "chondroitin sulfate synthase 3", "tax_id": 10116, "disease": "", "pathway": " (rno:291577); (R-RNO-2022870)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.-", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity;GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0032580 Golgi cisterna membrane", "go_biological_process": "GO:0050650 chondroitin sulfate proteoglycan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R6S5-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R6T4-1", "uniprot_id": [ { "id": "M0R6T4_RAT", "url": "https://www.uniprot.org/uniprot/M0R6T4", "type": "external" } ], "mass": 112932.0, "length": 1031, "protein_name": "MMS19 nucleotide excision repair protein", "gene_name": "Mms19", "organism": "Rat", "refseq_name": "MMS19 nucleotide excision repair protein homolog", "refseq_ac": [ { "id": "NP_001258525", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258525", "type": "external" } ], "gene_names_uniprotkb": "Mms19; 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In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0019899 enzyme binding;GO:0030331 nuclear estrogen receptor binding", "go_cellular_component": "GO:0097361 cytosolic [4Fe-4S] assembly targeting complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005819 spindle", "go_biological_process": "GO:0016226 iron-sulfur cluster assembly;GO:0006281 DNA repair;GO:0051604 protein maturation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "M0R6T4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R7C6-1", "uniprot_id": [ { "id": "M0R7C6_RAT", "url": "https://www.uniprot.org/uniprot/M0R7C6", "type": "external" } ], "mass": 41136.0, "length": 381, "protein_name": "Ankyrin repeat domain 33", "gene_name": "Ankrd33", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ankrd33", "gene_names_refseq": "", "protein_names_uniprotkb": "Ankyrin repeat domain 33", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0035914 skeletal muscle cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R7C6-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R7G2-1", "uniprot_id": [ { "id": "M0R7G2_RAT", "url": "https://www.uniprot.org/uniprot/M0R7G2", "type": "external" } ], "mass": 170586.0, "length": 1456, "protein_name": "LINE-1 retrotransposable element ORF1 protein", "gene_name": "AABR07043115.1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "AABR07043115.1", "gene_names_refseq": "", "protein_names_uniprotkb": "LINE-1 retrotransposable element ORF1 protein; 2.7.7.49; LINE retrotransposable element 1; LINE1 retrotransposable element 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Nucleic acid-binding protein which is essential for retrotransposition of LINE-1 elements in the genome. 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4.1.1.97; Parahox neighbor; Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase", "protein_names_refseq": "putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase", "tax_id": 10116, "disease": "", "pathway": " (rno:684055)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.1.1.97", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.97", "type": "external" } ], "go_molecular_function": "GO:0016831 carboxy-lyase activity;GO:0051997 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity", "go_cellular_component": "GO:0005777 peroxisome", "go_biological_process": "GO:0019628 urate catabolic process;GO:0006144 purine nucleobase metabolic process;GO:0000255 allantoin metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0RCU5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0RCY4-1", "uniprot_id": [ { "id": "M0RCY4_RAT", "url": "https://www.uniprot.org/uniprot/M0RCY4", "type": "external" } ], "mass": 27597.0, "length": 246, "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "AABR07000137.1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "AABR07000137.1", "gene_names_refseq": "", "protein_names_uniprotkb": "Retinoic acid early-inducible protein 1 domain-containing protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a ligand for KLRK1., [UniProtKB, UniProtKB]; 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0045095 keratin filament", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6APD8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6ASK8-1", "uniprot_id": [ { "id": "A0A8I6ASK8_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6ASK8", "type": "external" } ], "mass": 38615.0, "length": 365, "protein_name": "Ankyrin repeat domain 65", "gene_name": "Ankrd65", "organism": "Rat", "refseq_name": "ankyrin repeat domain-containing protein 65", "refseq_ac": [ { "id": "NP_001102897", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102897", "type": "external" } ], "gene_names_uniprotkb": "Ankrd65", "gene_names_refseq": "Ankrd65; 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[provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I5ZUY5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZV13-1", "uniprot_id": [ { "id": "A0A8I5ZV13_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZV13", "type": "external" } ], "mass": 79598.0, "length": 705, "protein_name": "eEF1A lysine and N-terminal methyltransferase", "gene_name": "Mettl13", "organism": "Rat", "refseq_name": "eEF1A lysine and N-terminal methyltransferase isoform 1", "refseq_ac": [ { "id": "NP_001127973", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001127973", "type": "external" } ], "gene_names_uniprotkb": "Mettl13", "gene_names_refseq": "Eef1aknmt; Mettl13; RGD1311526", "protein_names_uniprotkb": "eEF1A lysine and N-terminal methyltransferase; Methyltransferase-like protein 13", "protein_names_refseq": "eEF1A lysine and N-terminal methyltransferase isoform 1; eEF1A lysine and N-terminal methyltransferase; methyltransferase 13, eEF1A lysine and N-terminal methyltransferase; methyltransferase like 13; methyltransferase-like protein 13", "tax_id": 10116, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (rno:289159)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Dual methyltransferase that catalyzes methylation of elongation factor 1-alpha (EEF1A1 and EEF1A2) at two different positions, and is therefore involved in the regulation of mRNA translation. Via its C-terminus, methylates EEF1A1 and EEF1A2 at the N-terminal residue 'Gly-2'. Via its N-terminus dimethylates EEF1A1 and EEF1A2 at residue 'Lys-55'. Has no activity towards core histones H2A, H2B, H3 and H4., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016279 protein-lysine N-methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I5ZV13-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZWX3-1", "uniprot_id": [ { "id": "A0A8I5ZWX3_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZWX3", "type": "external" } ], "mass": 67913.0, "length": 604, "protein_name": "Adenosine deaminase-like", "gene_name": "Mapda", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Mapda; Adal", "gene_names_refseq": "", "protein_names_uniprotkb": "Adenosine deaminase-like", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Deaminase involved in the detoxification of modified adenosines containing N(6)-methylated adenine (m6A) post-transcriptional modification. Modified nucleosides are derived from the degradation of RNAs (mRNAs, rRNAs and tRNAs) and possess intrinsic cytotoxicity and must be cleared to prevent metabolic dysfunction. Acts downstream of ADK and catalyzes the hydrolysis of the free cytosolic methylated adenosine nucleotides N(6)-methyl-AMP (m6AMP), N(6),N(6)-dimethyl-AMP (m6,6AMP) and N(6)-isopentenyl-AMP (i6AMP) to produce inositol monophosphate (IMP). Catalyzes the removal of different alkyl groups not only from N6-substituted purine or 2-aminopurine nucleoside monophosphates but also from O6-substituted compounds in vitro., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0005198 structural molecule activity;GO:0003676 nucleic acid binding;GO:0062154 N6-methyl-AMP deaminase activity;GO:0046872 metal ion binding", "go_cellular_component": "", "go_biological_process": "GO:0016032 viral process;GO:0110052 toxic metabolite repair;GO:0009117 nucleotide metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I5ZWX3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZWY2-1", "uniprot_id": [ { "id": "A0A8I5ZWY2_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZWY2", "type": "external" } ], "mass": 34498.0, "length": 307, "protein_name": "Olfactory receptor", "gene_name": "Or1ad1", "organism": "Rat", "refseq_name": "olfactory receptor Olr1405", "refseq_ac": [ { "id": "NP_001001012", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001012", "type": "external" } ], "gene_names_uniprotkb": "Or1ad1", "gene_names_refseq": "Olr1405; Or1ad1", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1405; olfactory receptor Olr1405; olfactory receptor gene Olr1405", "tax_id": 10116, "disease": "", "pathway": " (rno:405386)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I5ZWY2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZWY4-1", "uniprot_id": [ { "id": "A0A8I5ZWY4_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZWY4", "type": "external" } ], "mass": 28449.0, "length": 256, "protein_name": "2-aminoethanethiol dioxygenase", "gene_name": "Ado", "organism": "Rat", "refseq_name": "2-aminoethanethiol dioxygenase", "refseq_ac": [ { "id": "NP_001101096", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101096", "type": "external" } ], "gene_names_uniprotkb": "Ado", "gene_names_refseq": "Ado; RGD1308233", "protein_names_uniprotkb": "2-aminoethanethiol dioxygenase", "protein_names_refseq": "2-aminoethanethiol (cysteamine) dioxygenase; 2-aminoethanethiol dioxygenase", "tax_id": 10116, "disease": "", "pathway": " (rno:309732); (R-RNO-1614558)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005506 iron ion binding;GO:0047800 cysteamine dioxygenase activity", "go_cellular_component": "", "go_biological_process": "GO:0071456 cellular response to hypoxia", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I5ZWY4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZX92-1", "uniprot_id": [ { "id": "A0A8I5ZX92_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZX92", "type": "external" } ], "mass": 37227.0, "length": 330, "protein_name": "Olfactory receptor", "gene_name": "Or12k5", "organism": "Rat", "refseq_name": "olfactory receptor Olr421", "refseq_ac": [ { "id": "NP_001000824", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000824", "type": "external" } ], "gene_names_uniprotkb": "Or12k5; Or12k7", "gene_names_refseq": "Olr421; Or12k5", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 421; olfactory receptor Olr421; olfactory receptor gene Olr421", "tax_id": 10116, "disease": "", "pathway": " (rno:296685); (rno:405113)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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Siat8e; St8siav", "gene_names_refseq": "SATV; SIAT8-E; SIAT8E; ST8SiaV; St8sia5", "protein_names_uniprotkb": "Alpha-2,8-sialyltransferase 8E; 2.4.99.-; SATV; SIAT8-E; ST8SiaV; Sialyltransferase 8E; Sialyltransferase St8Sia V", "protein_names_refseq": "ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 5; alpha-2,8-sialyltransferase 8E isoform 1; alpha-2,8-sialyltransferase 8E; sialyltransferase St8Sia V", "tax_id": 10116, "disease": "", "pathway": " (rno:364901); (R-RNO-4085001); (R-RNO-9840309)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "15843597;1606358;19103603", "class_list": "", "function": "Expression of St8sia5 increases over 15 fold at night in the rat pineal gland., [RefSeq, PubMed]; Involved in the synthesis of gangliosides GD1c, GT1a, GQ1b, GP1c and GT3 from GD1a, GT1b, GM1b and GD3 respectively., [UniProtKB, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A0G2JV41;E9PU47", "ec_number_list": [ { "id": "2.4.3.8", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.3.8", "type": "external" }, { "id": "2.4.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.3.-", "type": "external" }, { "id": "2.4.99.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.-", "type": "external" } ], "go_molecular_function": "GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity;GO:0008373 sialyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0006688 glycosphingolipid biosynthetic process;GO:0009311 oligosaccharide metabolic process;GO:0006491 N-glycan processing;GO:0009101 glycoprotein biosynthetic process", "synthesized_glycan_count": 21, "hit_score": 0.4, "record_id": "Q6ZXC8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "C0HLM6-1", "uniprot_id": [ { "id": "SIM20_RAT", "url": "https://www.uniprot.org/uniprot/C0HLM6", "type": "external" } ], "mass": 7800.0, "length": 69, "protein_name": "Small integral membrane protein 20", "gene_name": "Smim20", "organism": "Rat", "refseq_name": "small integral membrane protein 20", "refseq_ac": [ { "id": "NP_001128111", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001128111", "type": "external" } ], "gene_names_uniprotkb": "Smim20; AABR07015507.1", "gene_names_refseq": "MITRAC7; PNX; RGD1565192; Smim20", "protein_names_uniprotkb": "Small integral membrane protein 20; MITRAC7; Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 7 kDa", "protein_names_refseq": "mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 7 kDa; phoenixin; small integral membrane protein 20", "tax_id": 10116, "disease": "", "pathway": " (rno:501923)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "22963497;23912037;27440717;28844870;28965207;29364701;30251651;30609107;30930149;31422055;31637758;33059202;33928538;38870753", "class_list": "", "function": "Chronic unpredictable stress (CUS) reduced phoenixin expression, induced abnormal sperm and testis morphology in male rats., [RefSeq, PubMed]; Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly (By similarity). Promotes the progression of complex assembly after the association of Mt-Co1/Cox11 with Cox4I1 and Cox6c (By similarity). Chaperone-like assembly factor required to stabilize newly synthesized Mt-Co1/Cox1 and to prevent its premature turnover (By similarity)., [UniProtKB, UniProtKB]; Modulatory effect of olanzapine on SMIM20/phoenixin, NPQ/spexin and NUCB2/nesfatin-1 gene expressions in the rat brainstem., [RefSeq, PubMed]; Peptide involved in a broad spectrum of regulatory functions (PubMed:27440717, PubMed:28844870, PubMed:28965207, PubMed:29364701, PubMed:30609107). Is a ligand for GPR173 (PubMed:27440717). As part of the reproductive cycle, it regulates gonadotropin-releasing hormone (GnRH) signaling in the hypothalamus and pituitary gland which augments the release of luteinizing hormone (PubMed:22963497, PubMed:27440717). More specifically, it regulates the expression of transcription factors CEBPB and POU2F1/OCT1 through the cAMP-PKA signaling pathway, which subsequently regulate the expression of GNRHR and KISS1 (By similarity). Plays a protective role in memory retention through activation of GNRHR (By similarity). Regulates the secretion of AVP by hypothalamic neurons (PubMed:29364701). Plays a role in the transduction of the itch sensation (By similarity). Induces anxiolytic effects, reducing behavior associated with anxiety (By similarity). Regulates food intake as well as satiation and satiety by increasing NUCB2 expression in neurons (PubMed:28844870, PubMed:30930149). In the ovary, it regulates follicular growth by stimulating granulosa cell proliferation by increasing the expression of GPR173, CREB1, CYP19A1, KITLG, FSHR, and LHCGR (By similarity). It also increases the production of estradiol (E2) (By similarity). In the heart, it regulates contractility and relaxation by activating the AKT1-NOS3 and MAPK1-MAPK3 signaling pathways (PubMed:28965207). It also plays a cardioprotective role during ischemia, where it activates the SAFE and RISK pathways (PubMed:28965207). Stimulates the proliferation and differentiation of preadipocytes (PubMed:30251651). In pancreatic islet cells, it induces proliferation of islet cells as well as the production of INS1 and INS2 through activation of the MAPK1-MAPK3 signaling pathways (PubMed:31422055)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, UniProtKB, PubMed, PubMed, PubMed, PubMed, UniProtKB]; Phoenixin induced a significant enhancement in plasma FSH, LH and testosterone without inducing any alteration in plasma GnRH in the rats., [RefSeq, PubMed]; Phoenixin may represent a new class of hypothalamically-derived pituitary priming factors that sensitize the pituitary to the action of other releasing factors., [RefSeq, PubMed]; Restraint stress affects circulating NUCB2/nesfatin-1 and phoenixin levels in male rats., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0033617 mitochondrial respiratory chain complex IV assembly", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "C0HLM6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6ADK8-1", "uniprot_id": [ { "id": "A0A8I6ADK8_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6ADK8", "type": "external" } ], "mass": 180847.0, "length": 1614, "protein_name": "Rap guanine nucleotide exchange factor 6", "gene_name": "Rapgef6", "organism": "Rat", "refseq_name": "rap guanine nucleotide exchange factor 6 isoform X2", "refseq_ac": [ { "id": "XP_006246339", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006246339", "type": "external" } ], "gene_names_uniprotkb": "Rapgef6", "gene_names_refseq": "Rapgef6", "protein_names_uniprotkb": "Rap guanine nucleotide exchange factor 6", "protein_names_refseq": "rap guanine nucleotide exchange factor 6 isoform X2", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity;GO:0031267 small GTPase binding;GO:0030742 GTP-dependent protein binding;GO:0070300 phosphatidic acid binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0016324 apical plasma membrane;GO:0030139 endocytic vesicle;GO:0005737 cytoplasm", "go_biological_process": "GO:0032486 Rap protein signal transduction;GO:0031175 neuron projection development;GO:0007265 Ras protein signal transduction;GO:1903698 positive regulation of microvillus assembly;GO:0007264 small GTPase-mediated signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6ADK8-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZWS4-1", "uniprot_id": [ { "id": "A0A8I5ZWS4_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZWS4", "type": "external" } ], "mass": 83946.0, "length": 725, "protein_name": "Protein Hook homolog 3", "gene_name": "Hook3", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Hook3; AABR07026291.1", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein Hook homolog 3", "protein_names_refseq": "", "tax_id": 10116, "disease": "Emery-Dreifuss muscular dystrophy (Disease Ontology:DOID:11726)", "pathway": " (rno:306548)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Predominantly recruits 2 dyneins, which increases both the force and speed of the microtubule motor. Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). May regulate clearance of endocytosed receptors such as MSR1. Participates in defining the architecture and localization of the Golgi complex. FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding;GO:0042802 identical protein binding;GO:0034452 dynactin binding;GO:0051959 dynein light intermediate chain binding;GO:0045503 dynein light chain binding", "go_cellular_component": "GO:0030897 HOPS complex;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005874 microtubule;GO:0070695 FHF complex", "go_biological_process": "GO:0031122 cytoplasmic microtubule organization;GO:0015031 protein transport;GO:0007032 endosome organization;GO:0007040 lysosome organization;GO:0008333 endosome to lysosome transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I5ZWS4-1", "record_type": "protein", "filter_code": 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Parkinson's disease (Disease Ontology:DOID:14330); alcohol use disorder (Disease Ontology:DOID:1574)", "pathway": " (rno:302969); (R-RNO-72163); (R-RNO-9770562)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "16641100;22673903", "class_list": "", "function": "", "predicted_glycosites": 6, "predicted_n_glycosites": 0, "predicted_o_glycosites": 6, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0070742 C2H2 zinc finger domain binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005681 spliceosomal complex;GO:0016607 nuclear speck;GO:0015030 Cajal body;GO:0071013 catalytic step 2 spliceosome", "go_biological_process": "GO:0006397 mRNA processing;GO:0008380 RNA splicing;GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8I6A2Y2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A606-1", "uniprot_id": [ { "id": "A0A8I6A606_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A606", "type": "external" } ], "mass": 53953.0, "length": 484, "protein_name": "Suppressor of fused homolog", "gene_name": "Sufu", "organism": "Rat", "refseq_name": "suppressor of fused homolog isoform 2", "refseq_ac": [ { "id": "NP_001426873", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001426873", "type": "external" } ], "gene_names_uniprotkb": "Sufu", "gene_names_refseq": "Sufu", "protein_names_uniprotkb": "Suppressor of fused homolog", "protein_names_refseq": "suppressor of fused homolog isoform 2; 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Down-regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of GLI3 (GLI3FL). GLI3FL is complexed with SUFU in the cytoplasm and is maintained in a neutral state. Without the Hh signal, the SUFU-GLI3 complex is recruited to cilia, leading to the efficient processing of GLI3FL into GLI3R. When Hh signaling is initiated, SUFU dissociates from GLI3FL and the latter translocates to the nucleus, where it is phosphorylated, destabilized, and converted to a transcriptional activator (GLI3A)., [UniProtKB, UniProtKB, UniProtKB]; Through targeted inhibition of SUFU and activation of Hedgehog signaling pathway, miR-874 could promote the proliferation and differentiation of osteoblasts in osteoporosis rats. Erratum:[Biochem Biophys Res Commun. 2022 Dec 25;636(Pt 1):213. doi: 10.1016/j.bbrc.2022.10.084. 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"reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0032991 protein-containing complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I5ZSV2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A9H4-1", "uniprot_id": [ { "id": "A0A8I6A9H4_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A9H4", "type": "external" } ], "mass": 48206.0, "length": 433, "protein_name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "gene_name": "Art3", "organism": "Rat", "refseq_name": "", "refseq_ac": [], 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"external" }, { "id": "3.5.1.92", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.92", "type": "external" }, { "id": "3.2.2.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.2.6", "type": "external" }, { "id": "3.1.4.50", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.50", "type": "external" }, { "id": "3.4.11.9", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.11.9", "type": "external" } ], "go_molecular_function": "GO:0016779 nucleotidyltransferase activity;GO:0106274 NAD+-protein-arginine ADP-ribosyltransferase activity;GO:0003950 NAD+ poly-ADP-ribosyltransferase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0098552 side of membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6A9H4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5Y9U2-1", "uniprot_id": [ { "id": "A0A8I5Y9U2_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5Y9U2", "type": "external" } ], "mass": 61081.0, "length": 553, "protein_name": "CCR4-NOT transcription complex subunit 2", "gene_name": "Cnot2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Cnot2", "gene_names_refseq": "", "protein_names_uniprotkb": "CCR4-NOT transcription complex subunit 2; CCR4-associated factor 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:299805); (R-RNO-6804115)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, 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P-body;GO:0030014 CCR4-NOT complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:2000036 regulation of stem cell population maintenance;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0001829 trophectodermal cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I5Y9U2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A4F2-1", "uniprot_id": [ { "id": "A0A8I6A4F2_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A4F2", "type": "external" } ], "mass": 73766.0, "length": 656, "protein_name": "Integrator complex subunit 9", "gene_name": "Ints9", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ints9", "gene_names_refseq": "", "protein_names_uniprotkb": "Integrator complex subunit 9", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:290322); (R-RNO-6807505)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the integrator complex, a multiprotein complex that terminates RNA polymerase II (Pol II) transcription in the promoter-proximal region of genes. The integrator complex provides a quality checkpoint during transcription elongation by driving premature transcription termination of transcripts that are unfavorably configured for transcriptional elongation: the complex terminates transcription by (1) catalyzing dephosphorylation of the C-terminal domain (CTD) of Pol II subunit POLR2A/RPB1 and SUPT5H/SPT5, (2) degrading the exiting nascent RNA transcript via endonuclease activity and (3) promoting the release of Pol II from bound DNA. The integrator complex is also involved in terminating the synthesis of non-coding Pol II transcripts, such as enhancer RNAs (eRNAs), small nuclear RNAs (snRNAs), telomerase RNAs and long non-coding RNAs (lncRNAs). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the integrator complex., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0032039 integrator complex;GO:0160232 INTAC complex;GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0090287 regulation of cellular response to growth factor stimulus;GO:0034472 snRNA 3'-end processing;GO:0160240 RNA polymerase II transcription initiation surveillance;GO:0034243 regulation of transcription elongation by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6A4F2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZYG1-1", "uniprot_id": [ { "id": "A0A8I5ZYG1_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZYG1", "type": "external" } ], "mass": 102251.0, "length": 903, "protein_name": "Oxysterol-binding protein", "gene_name": "Osbpl5", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Osbpl5", "gene_names_refseq": "", "protein_names_uniprotkb": "Oxysterol-binding protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:361686); (R-RNO-1482801)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane: specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum. Binds phosphatidylserine and PI4P in a mutually exclusive manner. May cooperate with NPC1 to mediate the exit of cholesterol from endosomes/lysosomes. Binds 25-hydroxycholesterol and cholesterol., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015485 cholesterol binding;GO:0008289 lipid binding;GO:0070273 phosphatidylinositol-4-phosphate binding;GO:0001786 phosphatidylserine binding;GO:0140343 phosphatidylserine transfer activity", "go_cellular_component": "GO:0005829 cytosol;GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane;GO:0140268 endoplasmic reticulum-plasma membrane contact site;GO:1990351 transporter complex", "go_biological_process": "GO:0015914 phospholipid transport;GO:0006869 lipid transport;GO:0120010 intermembrane phospholipid transfer", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I5ZYG1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6GKW7-1", "uniprot_id": [ { "id": "A0A8I6GKW7_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6GKW7", "type": "external" } ], "mass": 106346.0, "length": 926, "protein_name": "Antiviral innate immune response receptor RIG-I", "gene_name": "Rig1", "organism": "Rat", "refseq_name": "antiviral innate immune response receptor RIG-I", "refseq_ac": [ { "id": "NP_001382000", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382000", "type": "external" } ], "gene_names_uniprotkb": "Rig1", "gene_names_refseq": "Ddx58; Rig1; Rigi", "protein_names_uniprotkb": "Antiviral innate immune response receptor RIG-I; 3.6.4.13; ATP-dependent RNA helicase DDX58; DEAD box protein 58; RIG-I-like receptor 1; RNA sensor RIG-I; Retinoic acid-inducible gene 1 protein; Retinoic acid-inducible gene I protein", "protein_names_refseq": "DEAD (Asp-Glu-Ala-Asp) box polypeptide 58; DEXD/H-box helicase 58; antiviral innate immune response receptor RIG-I; probable ATP-dependent RNA helicase DDX58", "tax_id": 10116, "disease": "Fanconi anemia (Disease Ontology:DOID:13636)", "pathway": " (rno:297989); (R-RNO-1169408); (R-RNO-5689880); (R-RNO-8983711); (R-RNO-936440); (R-RNO-9909505)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.1.5", "url": 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that encodes the first 3 enzymatic activities of the de novo pyrimidine pathway: carbamoylphosphate synthetase (CPSase; EC 6.3.5.5), aspartate transcarbamylase (ATCase; EC 2.1.3.2) and dihydroorotase (DHOase; EC 3.5.2.3). The CPSase-function is accomplished in 2 steps, by a glutamine-dependent amidotransferase activity (GATase) that binds and cleaves glutamine to produce ammonia, followed by an ammonium-dependent carbamoyl phosphate synthetase, which reacts with the ammonia, hydrogencarbonate and ATP to form carbamoyl phosphate. The endogenously produced carbamoyl phosphate is sequestered and channeled to the ATCase active site. ATCase then catalyzes the formation of carbamoyl-L-aspartate from L-aspartate and carbamoyl phosphate. In the last step, DHOase catalyzes the cyclization of carbamoyl aspartate to dihydroorotate., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.3.4.16", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.4.16", "type": "external" }, { "id": "2.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.3.2", "type": "external" }, { "id": "3.5.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.2.3", "type": "external" }, { "id": "6.3.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.5.5", "type": "external" }, { "id": "3.5.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.2", "type": "external" } ], "go_molecular_function": "GO:0004087 carbamoyl-phosphate synthase (ammonia) activity;GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity;GO:0004151 dihydroorotase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0043025 neuronal cell body;GO:0043195 terminal bouton", "go_biological_process": "GO:0006520 amino acid metabolic process;GO:0006541 glutamine metabolic process;GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process;GO:0044205 'de novo' UMP biosynthetic process;GO:0019240 citrulline biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I5ZMM2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5YBG5-1", "uniprot_id": [ { "id": "A0A8I5YBG5_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5YBG5", "type": "external" } ], "mass": 199017.0, "length": 1755, "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "Ubr2", "organism": "Rat", "refseq_name": "E3 ubiquitin-protein ligase UBR2 isoform 1", "refseq_ac": [ { "id": "NP_001399747", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001399747", "type": "external" } ], "gene_names_uniprotkb": "Ubr2", "gene_names_refseq": "Ubr2", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase; 2.3.2.27", "protein_names_refseq": "E3 ubiquitin-protein ligase UBR2 isoform 1; E3 ubiquitin-protein ligase UBR2", "tax_id": 10116, "disease": "metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); neurodegenerative disease (Disease Ontology:DOID:1289)", "pathway": " (R-RNO-983168)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "38843836", "class_list": "", "function": "Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "2.3.2.32", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.32", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "2.3.2.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.24", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0070728 L-leucine binding;GO:0141053 histone H2A ubiquitin ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000785 chromatin;GO:0000151 ubiquitin ligase complex", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway;GO:0007283 spermatogenesis;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0050862 positive regulation of T cell receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A8I5YBG5-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A346-1", "uniprot_id": [ { "id": "A0A8I6A346_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A346", "type": "external" } ], "mass": 34978.0, "length": 312, "protein_name": "Olfactory receptor 1177", "gene_name": "Olr1177; Or7e173d", "organism": "Rat", "refseq_name": "olfactory receptor Olr1177", "refseq_ac": [ { "id": "NP_001000865", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000865", "type": "external" } ], "gene_names_uniprotkb": "Olr1177; Or7e173d; Olr1177; Or7e173", "gene_names_refseq": "Olr1177", "protein_names_uniprotkb": "Olfactory receptor 1177", "protein_names_refseq": "olfactory receptor Olr1177; olfactory receptor gene Olr1177", "tax_id": 10116, "disease": "", "pathway": " (rno:405160); (rno:405373)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6A346-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A588-1", "uniprot_id": [ { "id": "A0A8I6A588_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A588", "type": "external" } ], "mass": 30030.0, "length": 254, "protein_name": "ETS-related transcription factor Elf-5", "gene_name": "Elf5", "organism": "Rat", "refseq_name": "ETS-related transcription factor Elf-5 isoform X1", "refseq_ac": [ { "id": "XP_008760292", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008760292", "type": "external" } ], "gene_names_uniprotkb": "Elf5", "gene_names_refseq": "Elf5", "protein_names_uniprotkb": "ETS-related transcription factor Elf-5; E74-like factor 5", "protein_names_refseq": "ETS-related transcription factor Elf-5 isoform X1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:1990837 sequence-specific double-stranded DNA binding;GO:0003700 DNA-binding transcription factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007398 ectoderm development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6A588-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5YBL2-1", "uniprot_id": [ { "id": "A0A8I5YBL2_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5YBL2", "type": "external" } ], "mass": 103660.0, "length": 913, "protein_name": "Tyrosine-protein phosphatase non-receptor type", "gene_name": "Ptpn3", "organism": "Rat", "refseq_name": "tyrosine-protein phosphatase non-receptor type 3", "refseq_ac": [ { "id": "NP_001094224", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094224", "type": "external" } ], "gene_names_uniprotkb": "Ptpn3", "gene_names_refseq": "Ptpn3", "protein_names_uniprotkb": "Tyrosine-protein phosphatase non-receptor type; 3.1.3.48", "protein_names_refseq": "tyrosine-protein phosphatase non-receptor type 3", "tax_id": 10116, "disease": "", "pathway": " (rno:362524); (R-RNO-182971); (R-RNO-5675221)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May act at junctions between the membrane and the cytoskeleton., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21", "type": "external" }, { "id": "3.1.3.18", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.18", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" }, { "id": "3.1.3.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.5", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" } ], "go_molecular_function": "GO:0008092 cytoskeletal protein binding;GO:0004725 protein tyrosine phosphatase activity;GO:0001784 phosphotyrosine residue binding;GO:0051117 ATPase binding;GO:0017080 sodium channel regulator activity", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005737 cytoplasm;GO:0009898 cytoplasmic side of plasma membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0051045 negative regulation of membrane protein ectodomain proteolysis;GO:0045930 negative regulation of mitotic cell cycle;GO:0097421 liver regeneration;GO:0098902 regulation of membrane depolarization during action potential;GO:1902305 regulation of sodium ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I5YBL2-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JUW3-1", "uniprot_id": [ { "id": "A0A0G2JUW3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JUW3", "type": "external" } ], "mass": 64318.0, "length": 574, "protein_name": "Cysteine-rich secretory protein LCCL domain containing 2", "gene_name": "Crispld2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Crispld2", "gene_names_refseq": "", "protein_names_uniprotkb": "Cysteine-rich secretory protein LCCL domain containing 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "orofacial cleft (Disease Ontology:DOID:0050567)", "pathway": " (R-RNO-6798695)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, 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Erythrocyte ankyrins also link spectrin (beta chain) to the cytoplasmic domain of the erythrocytes anion exchange protein; they retain most or all of these binding functions., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019899 enzyme binding;GO:0051117 ATPase binding;GO:0044325 transmembrane transporter binding;GO:0030507 spectrin binding;GO:0008093 cytoskeletal anchor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0045211 postsynaptic membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0055085 transmembrane transport;GO:0072659 protein localization to plasma membrane;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006779 porphyrin-containing compound biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I5ZJ94-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZQZ7-1", "uniprot_id": [ { "id": "A0A8I5ZQZ7_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZQZ7", "type": "external" } ], "mass": 71502.0, "length": 612, "protein_name": "Zinc finger protein 655", "gene_name": "Zfp655", "organism": "Rat", "refseq_name": "zinc finger protein 655 isoform 1", "refseq_ac": [ { "id": "NP_001424414", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001424414", "type": "external" } ], "gene_names_uniprotkb": "Zfp655", "gene_names_refseq": "RGD1309158; 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"ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0140870 RNA polymerase inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0016604 nuclear body;GO:0032021 NELF complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription;GO:0034244 negative regulation of transcription elongation by RNA polymerase II;GO:0160239 transcription pausing by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6B5Y3-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5YC36-1", "uniprot_id": [ { "id": "A0A8I5YC36_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5YC36", "type": "external" } ], "mass": 347327.0, "length": 3114, "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "Ranbp2", "organism": "Rat", 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to be essential for maintaining mitochondrial cristae formation and mitochondrial function by acting via YME1L1 in a kinase-independent manner to regulate essential mitochondrial structural proteins OPA1 and IMMT. The action of this enzyme is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, 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{ "id": "A0A8I6G5G3_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6G5G3", "type": "external" } ], "mass": 31941.0, "length": 286, "protein_name": "Transport and golgi organization 2 homolog", "gene_name": "Tango2", "organism": "Rat", "refseq_name": "transport and Golgi organization protein 2 homolog isoform X6", "refseq_ac": [ { "id": "XP_038944437", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038944437", "type": "external" } ], "gene_names_uniprotkb": "Tango2; RGD1310348", "gene_names_refseq": "RGD1310348; Tango2", "protein_names_uniprotkb": "Transport and golgi organization 2 homolog", "protein_names_refseq": "transport and Golgi organization protein 2 homolog isoform X6", "tax_id": 10116, "disease": "TANGO2-related metabolic encephalopathy and arrythmias (Disease Ontology:DOID:0081386)", "pathway": " (rno:360738)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, 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"external" } ], "gene_names_uniprotkb": "Evi5", "gene_names_refseq": "Evi5", "protein_names_uniprotkb": "Ecotropic viral integration site 5", "protein_names_refseq": "ecotropic viral integration site 5 protein homolog isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:100360066)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, 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"0000000.0000001.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6GDZ5-1", "uniprot_id": [ { "id": "A0A8I6GDZ5_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6GDZ5", "type": "external" } ], "mass": 43852.0, "length": 385, "protein_name": "tRNA N(3)-cytidine methyltransferase", "gene_name": "Mettl2", "organism": "Rat", "refseq_name": "methyltransferase-like protein 2A", "refseq_ac": [ { "id": "NP_001102309", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102309", "type": "external" } ], "gene_names_uniprotkb": "Mettl2; Mettl2b", "gene_names_refseq": "Mettl2a; Mettl2b; Mettl2", "protein_names_uniprotkb": "tRNA N(3)-cytidine methyltransferase; 2.1.1.-", "protein_names_refseq": "methyltransferase 2, tRNA N3-cytidine; methyltransferase like 2B; methyltransferase-like protein 2A", "tax_id": 10116, "disease": "", "pathway": " (rno:363687)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", 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Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core). In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A forming an intermediate. 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Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0150047 G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential", "go_cellular_component": "GO:0043235 receptor complex;GO:0045211 postsynaptic membrane;GO:0042734 presynaptic membrane;GO:0048787 presynaptic active zone membrane;GO:0098794 postsynapse", "go_biological_process": "GO:0051260 protein homooligomerization;GO:0008277 regulation of G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A6Y7S3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B0BNE7-1", "uniprot_id": [ { "id": "B0BNE7_RAT", "url": "https://www.uniprot.org/uniprot/B0BNE7", "type": "external" } ], "mass": 27544.0, "length": 249, "protein_name": "Tetraspanin", "gene_name": "Tspan7", "organism": "Rat", "refseq_name": "tetraspanin-7", "refseq_ac": [ { "id": "NP_001385666", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385666", "type": "external" } ], "gene_names_uniprotkb": "Tspan7", "gene_names_refseq": "A15; DXS1692E; MXS1; TALLA-1; Tm4sf2; Tspan7", "protein_names_uniprotkb": "Tetraspanin", "protein_names_refseq": "Transmembrane 4, superfamily member 2 (cell surface glycoprotein A15); neuroprotective protein 5; tetraspanin-7; transmembrane 4 superfamily member 2", "tax_id": 10116, "disease": "non-syndromic X-linked intellectual disability 58 (Disease Ontology:DOID:0112024)", "pathway": " (rno:363447); (R-RNO-416993)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "36625203", "class_list": "", "function": "Integrin beta1/FAK/SRC signal pathway is involved in autism spectrum disorder in Tspan7 knockout rats. Publication Status: Online-Only, [RefSeq, PubMed]; May be involved in cell proliferation and cell motility., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1M9I6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0098794 postsynapse", "go_biological_process": "GO:0099149 regulation of postsynaptic neurotransmitter receptor internalization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "B0BNE7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F7EM85-1", "uniprot_id": [ { "id": "F7EM85_RAT", "url": "https://www.uniprot.org/uniprot/F7EM85", "type": "external" } ], "mass": 44009.0, "length": 399, "protein_name": "F-box protein 22", "gene_name": "Fbxo22", "organism": "Rat", "refseq_name": "F-box only protein 22", "refseq_ac": [ { "id": "NP_001032859", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032859", "type": "external" } ], "gene_names_uniprotkb": "Fbxo22", "gene_names_refseq": "Fbxo22", "protein_names_uniprotkb": "F-box protein 22", "protein_names_refseq": "F-box only protein 22", "tax_id": 10116, "disease": "", "pathway": " (rno:300724); (R-RNO-8951664); (R-RNO-983168)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0010830 regulation of myotube differentiation;GO:0048742 regulation of skeletal muscle fiber development;GO:0006913 nucleocytoplasmic transport;GO:0000209 protein polyubiquitination;GO:0009267 cellular response to starvation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F7EM85-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F7FJV3-1", "uniprot_id": [ { "id": "F7FJV3_RAT", "url": "https://www.uniprot.org/uniprot/F7FJV3", "type": "external" } ], "mass": 42930.0, "length": 387, "protein_name": "cAMP responsive element binding protein 3", "gene_name": "Creb3", "organism": "Rat", "refseq_name": "cyclic AMP-responsive element-binding protein 3", "refseq_ac": [ { "id": "NP_001382561", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382561", "type": "external" } ], "gene_names_uniprotkb": "Creb3", "gene_names_refseq": "Creb3", "protein_names_uniprotkb": "cAMP responsive element binding protein 3", "protein_names_refseq": "cyclic AMP-responsive element-binding protein 3", "tax_id": 10116, "disease": "", "pathway": " (rno:298400)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "25349404;26511246;30863858;37678424", "class_list": "", "function": "Alterations in neuronal injury-associated Luman/CREB3 expression support that a multiphasic cell body response occurs and reveal a novel contralateral plasticity in axon growth capacity at 1-week post-injury, [RefSeq, PubMed]; Identification of creb3 as a regulator of the injury-induced unfolded protein response and cholesterol at levels that benefit the intrinsic ability of axotomized adult rat sensory neurons to undergo axonal regeneration reveals new therapeutic targets, [RefSeq, PubMed]; Sensing nerve injury at the axonal ER: activated Luman/CREB3 serves as a novel axonally synthesized retrograde regeneration signal., [RefSeq, PubMed]; Transplantation of endothelial progenitor cells improves myocardial hypertrophy in spontaneously hypertensive rats through HO-1/CREB3/AKT axis., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0003700 DNA-binding transcription factor activity;GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0090045 positive regulation of deacetylase activity;GO:0006351 DNA-templated transcription;GO:0030335 positive regulation of cell migration;GO:0042127 regulation of cell population proliferation;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "F7FJV3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q4TU74-1", "uniprot_id": [ { "id": "Q4TU74_RAT", "url": "https://www.uniprot.org/uniprot/Q4TU74", "type": "external" } ], "mass": 25455.0, "length": 227, "protein_name": "Reproductive homeobox 9 like 1", "gene_name": "Rhoxf9", "organism": "Rat", "refseq_name": "Rhox homeobox family member 9", "refseq_ac": [ { "id": "NP_001020045", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020045", "type": "external" } ], "gene_names_uniprotkb": "Rhoxf9; Rhox9", "gene_names_refseq": "Psx4; Rhox9; Rhoxf9", "protein_names_uniprotkb": "Reproductive homeobox 9 like 1", "protein_names_refseq": "Rhox homeobox family member 9; homeobox protein PSX4; reproductive homeobox 9; reproductive homeobox on X chromosome, 9", "tax_id": 10116, "disease": "", "pathway": " (rno:298352)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "M0R9K0", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q4TU74-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5FVP4-1", "uniprot_id": [ { "id": "Q5FVP4_RAT", "url": "https://www.uniprot.org/uniprot/Q5FVP4", "type": "external" } ], "mass": 66698.0, "length": 580, "protein_name": "Zinc finger protein 271", "gene_name": "Zfp35", "organism": "Rat", "refseq_name": "zinc finger protein 271", "refseq_ac": [ { "id": "NP_001013159", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013159", "type": "external" } ], "gene_names_uniprotkb": "Zfp35", "gene_names_refseq": "Zfp239; Zfp35", "protein_names_uniprotkb": "Zinc finger protein 271", "protein_names_refseq": "zinc finger protein 239; zinc finger protein 271", "tax_id": 10116, "disease": "", "pathway": " (rno:307547)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A096MJ05", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045596 negative regulation of cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q5FVP4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5M857-1", "uniprot_id": [ { "id": "Q5M857_RAT", "url": "https://www.uniprot.org/uniprot/Q5M857", "type": "external" } ], "mass": 45253.0, "length": 399, "protein_name": "Cyclin B2", "gene_name": "Ccnb2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ccnb2", "gene_names_refseq": "", "protein_names_uniprotkb": "Cyclin B2", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:363088); (R-RNO-2500257); (R-RNO-2565942); (R-RNO-2980767); (R-RNO-2995383); (R-RNO-3301854); (R-RNO-69273); (R-RNO-69478); (R-RNO-8852276)", "pathway_count": 9, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Essential for the control of the cell cycle at the G2/M (mitosis) transition., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0005813 centrosome;GO:0005829 cytosol", "go_biological_process": "GO:0001701 in utero embryonic development;GO:0040008 regulation of growth;GO:0051301 cell division;GO:0048538 thymus development;GO:0000082 G1/S transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q5M857-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5UCE3-1", "uniprot_id": [ { "id": "Q5UCE3_RAT", "url": "https://www.uniprot.org/uniprot/Q5UCE3", "type": "external" } ], "mass": 40918.0, "length": 366, "protein_name": "Left-right determination factor", "gene_name": "Lefty2", "organism": "Rat", "refseq_name": "left-right determination factor 2 precursor", "refseq_ac": [ { "id": "NP_001007557", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007557", "type": "external" } ], "gene_names_uniprotkb": "Lefty2", "gene_names_refseq": "Ebaf2; Lefty2", "protein_names_uniprotkb": "Left-right determination factor", "protein_names_refseq": "endometrial bleeding associated factor; left-right determination factor 2 precursor", "tax_id": 10116, "disease": "congenital heart disease (Disease Ontology:DOID:1682)", "pathway": " (rno:289316); (R-RNO-114608)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "17507784;21205391;31418961;32745796;34737126", "class_list": "", "function": "LEFTY2 alleviates hepatic stellate cell activation and liver fibrosis by regulating the TGF-beta1/Smad3 pathway., [RefSeq, PubMed]; LEFTY2 is expressed at a high level just before the embryos pass to the uterus; its biological effect might be relevant and significant for the preimplantation stage of embryo development in the oviduct., [RefSeq, PubMed]; Role of EBAF/Nodal/p27 signaling pathway in development of placenta in normal and diabetic rats., [RefSeq, PubMed]; The highest expression of lefty2 was at the 4(th) day after mating (five folds respect to day one), just when the embryos have completed their transit through the oviduct., [RefSeq, PubMed]; These observations have shed new light on the relevance of the NODAL/LEFTY2 pathway in the oviduct during early embryo development and the role of the embryo in modulating this pathway., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A0G2K998", "ec_number_list": [], "go_molecular_function": "GO:0005125 cytokine activity;GO:0005160 transforming growth factor beta receptor binding;GO:0008083 growth factor activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0030509 BMP signaling pathway;GO:0009948 anterior/posterior axis specification", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q5UCE3-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q672J3-1", "uniprot_id": [ { "id": "Q672J3_RAT", "url": "https://www.uniprot.org/uniprot/Q672J3", "type": "external" } ], "mass": 86360.0, "length": 757, "protein_name": "Zinc finger and BTB domain containing 1", "gene_name": "Zbtb1", "organism": "Rat", "refseq_name": "zinc finger and BTB domain-containing protein 1 isoform X1", "refseq_ac": [ { "id": "XP_038968200", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038968200", "type": "external" } ], "gene_names_uniprotkb": "Zbtb1", "gene_names_refseq": "Zbtb1", "protein_names_uniprotkb": "Zinc finger and BTB domain containing 1", "protein_names_refseq": "zinc finger and BTB domain-containing protein 1 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:314246)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "E9PT64", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0070530 K63-linked polyubiquitin modification-dependent protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0031965 nuclear membrane;GO:0016604 nuclear body", "go_biological_process": "GO:0002711 positive regulation of T cell mediated immunity;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006281 DNA repair;GO:0006338 chromatin remodeling;GO:0051260 protein homooligomerization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q672J3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q67ER1-1", "uniprot_id": [ { "id": "Q67ER1_RAT", "url": "https://www.uniprot.org/uniprot/Q67ER1", "type": "external" } ], "mass": 38028.0, "length": 337, "protein_name": "Ring finger protein 113A2", "gene_name": "Rnf113a2", "organism": "Rat", "refseq_name": "zinc finger protein 183 (RING finger, C3HC4 type)", "refseq_ac": [ { "id": "NP_001004445", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004445", "type": "external" } ], "gene_names_uniprotkb": "Rnf113a2", "gene_names_refseq": "Rnf113a2; Znf183", "protein_names_uniprotkb": "Ring finger protein 113A2", "protein_names_refseq": "zinc finger protein 183 (RING finger, C3HC4 type)", "tax_id": 10116, "disease": "nonphotosensitive trichothiodystrophy 5 (Disease Ontology:DOID:0111868)", "pathway": " (rno:314313); (R-RNO-72163)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005684 U2-type spliceosomal complex", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q67ER1-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6MG00-1", "uniprot_id": [ { "id": "Q6MG00_RAT", "url": "https://www.uniprot.org/uniprot/Q6MG00", "type": "external" } ], "mass": 20331.0, "length": 181, "protein_name": "RT1 class Ib, locus O1", "gene_name": "RT1-O1", "organism": "Rat", "refseq_name": "RT1 class Ib, locus O1", "refseq_ac": [ { "id": "NP_001008856", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008856", "type": "external" } ], "gene_names_uniprotkb": "RT1-O1", "gene_names_refseq": "Qlikea; RT1-O1; RT1-O", "protein_names_uniprotkb": "RT1 class Ib, locus O1", "protein_names_refseq": "RT1 class Ib gene, H2-Q-like, grc region; RT1 class Ib, locus H2-Q-like, grc region; RT1 class Ib, locus O1", "tax_id": 10116, "disease": "", "pathway": " (rno:24751)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in the presentation of foreign antigens to the immune system., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A0G2JT60", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0030670 phagocytic vesicle membrane;GO:0042612 MHC class I protein complex;GO:0098553 lumenal side of endoplasmic reticulum membrane", "go_biological_process": "GO:0002474 antigen processing and presentation of peptide antigen via MHC class I", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q6MG00-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6P4Z7-1", "uniprot_id": [ { "id": "Q6P4Z7_RAT", "url": "https://www.uniprot.org/uniprot/Q6P4Z7", "type": "external" } ], "mass": 17825.0, "length": 166, "protein_name": "Cyclin-dependent kinase 4 inhibitor D", "gene_name": "Cdkn2d", "organism": "Rat", "refseq_name": "cyclin-dependent kinase 4 inhibitor D", "refseq_ac": [ { "id": "NP_001009719", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001009719", "type": "external" } ], "gene_names_uniprotkb": "Cdkn2d", "gene_names_refseq": "Cdkn2d", "protein_names_uniprotkb": "Cyclin-dependent kinase 4 inhibitor D; p19-INK4d", "protein_names_refseq": "cyclin-dependent kinase 4 inhibitor D", "tax_id": 10116, "disease": "", "pathway": " (rno:494444); (R-RNO-2559580); (R-RNO-2559582); (R-RNO-2559585); (R-RNO-69231)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "26722409", "class_list": "", "function": "Interacts strongly with CDK4 and CDK6 and inhibits them., [UniProtKB, UniProtKB]; P19 may play an important role in the ototoxic effects of cisplatin and is probably involved in the pathogenesis of hearing loss. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0097129 cyclin D2-CDK4 complex", "go_biological_process": "GO:0008285 negative regulation of cell population proliferation;GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0032526 response to retinoic acid;GO:0030308 negative regulation of cell growth;GO:0009411 response to UV", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q6P4Z7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6QI29-1", "uniprot_id": [ { "id": "Q6QI29_RAT", "url": "https://www.uniprot.org/uniprot/Q6QI29", "type": "external" } ], "mass": 12633.0, "length": 111, "protein_name": "Uncharacterized protein", "gene_name": "", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F7FLV0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q6QI29-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q76M99-1", "uniprot_id": [ { "id": "S22AO_RAT", "url": "https://www.uniprot.org/uniprot/Q76M99", "type": "external" } ], "mass": 60981.0, "length": 551, "protein_name": "Steroid transmembrane transporter SLC22A24", "gene_name": "Slc22a24", "organism": "Rat", "refseq_name": "steroid transmembrane transporter SLC22A24", "refseq_ac": [ { "id": "NP_775424", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775424", "type": "external" } ], "gene_names_uniprotkb": "Slc22a24; Slc22a19; Slc22a9", "gene_names_refseq": "Oat5; Slc22a19; Slc22a24; Slc22a9; rOat5", "protein_names_uniprotkb": "Steroid transmembrane transporter SLC22A24; Organic anion transporter 5; Solute carrier family 22 member 24; rOat5", "protein_names_refseq": "organic anion transporter 5; solute carrier family 22 (organic anion transporter), member 19; solute carrier family 22 (organic anion transporter), member 9; solute carrier family 22 (organic anion/cation transporter), member 9; solute carrier family 22 member 10; solute carrier family 22, member 24; steroid transmembrane transporter SLC22A24", "tax_id": 10116, "disease": "mismatch repair cancer syndrome (Disease Ontology:DOID:0112182); Lynch syndrome (Disease Ontology:DOID:3883)", "pathway": " (rno:286961)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "15068970;16079298;18796410;20865662;24199190;26269671;31553721;32497308", "class_list": "", "function": "An increased expression of Oat5 in renal homogenates, in apical membranes, and in its urinary excretion was observed in rats with vascular calcification., [RefSeq, PubMed]; Cholestasis induced by common bile duct ligation in the rat induces upregulation of Oat5 in kidneys., [RefSeq, PubMed]; Highly expressed in kidney. Motive forces behind Oat5 function, which provide insight into its membrane localization, need to be further resolved., [RefSeq, PubMed]; ROat5 is renal organic anion/dicarboxylates exchanger and, under physiological conditions, may function as an apical reabsorptive pathway, [RefSeq, PubMed]; Renal expression of Oat5 in rats (and mice) exhibits zonal and sex differences, [RefSeq, PubMed]; Renal transmembrane organic anion/dicarboxylate exchanger that participates in the reabsorption of conjugated steroids, as well as bile acids, driven by an outward gradient of dicarboxylates such as glutarate or succinate (PubMed:16079298). Transports estrone 3-sulfate and estradiol-17-glucuronide (17beta-estradiol 17-O-(beta-D-glucuronate)), but not androstanediol glucuronide (5alpha-androstane-3alpha,17beta-diol 3-O-(beta-D-glucuronate)), nor taurocholate (PubMed:31553721). Prefers sulfate conjugates of steroids rather than glucuronide conjugates (PubMed:16079298)., [UniProtKB, PubMed, PubMed]; Urinary excretion of Oat5 might be an early indicator of renal dysfunction, [RefSeq, PubMed]; Utility of urinary organic anion transporter 5 as an early biomarker of obstructive nephropathy., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0019534 toxin transmembrane transporter activity", "go_cellular_component": "GO:0016324 apical plasma membrane", "go_biological_process": "GO:0006811 monoatomic ion transport;GO:0015711 organic anion transport;GO:0043252 sodium-independent organic anion transport;GO:0008202 steroid metabolic process;GO:0002238 response to molecule of fungal origin", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q76M99-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q7TNA8-1", "uniprot_id": [ { "id": "Q7TNA8_RAT", "url": "https://www.uniprot.org/uniprot/Q7TNA8", "type": "external" } ], "mass": 42049.0, "length": 382, "protein_name": "L-lactate dehydrogenase", "gene_name": "Ldhal6b", "organism": "Rat", "refseq_name": "L-lactate dehydrogenase A-like 6B", "refseq_ac": [ { "id": "NP_899163", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_899163", "type": "external" } ], "gene_names_uniprotkb": "Ldhal6b", "gene_names_refseq": "Ldhal6b; Ldhl", "protein_names_uniprotkb": "L-lactate dehydrogenase; 1.1.1.27", "protein_names_refseq": "L-lactate dehydrogenase A-like 6B", "tax_id": 10116, "disease": "disease of metabolism (Disease Ontology:DOID:0014667)", "pathway": " (rno:369018); (R-RNO-70268)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", 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0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.1.27", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.27", "type": "external" } ], "go_molecular_function": "GO:0051287 NAD binding;GO:0004459 L-lactate dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0019674 NAD+ metabolic process;GO:0006089 lactate metabolic process;GO:0042867 pyruvate catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q7TNA8-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q80ZF4-1", "uniprot_id": [ { "id": "Q80ZF4_RAT", "url": "https://www.uniprot.org/uniprot/Q80ZF4", "type": "external" } ], "mass": 44036.0, "length": 386, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Mapkapk2", "organism": "Rat", "refseq_name": "MAP kinase-activated protein kinase 2", "refseq_ac": [ { "id": "NP_835203", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_835203", "type": "external" } ], "gene_names_uniprotkb": "Mapkapk2", "gene_names_refseq": "Mapkapk2", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "MAP kinase-activated protein kinase 2; mitogen-activated protein kinase-activated protein kinase 2", "tax_id": 10116, "disease": "", "pathway": " (rno:289014); (R-RNO-171007); (R-RNO-199920); (R-RNO-2142691); (R-RNO-2559580); (R-RNO-3371453); (R-RNO-4420097); (R-RNO-450302); (R-RNO-450385); (R-RNO-450513); (R-RNO-5357905)", "pathway_count": 11, "publication_count": 2, "publication_id_list": "21139061;24927932", "class_list": "", "function": "Is suggested that renal protective effect may be related to MAPKAPK-2 activation in the reduction of renal ischemia-reperfusion injury by ischemic postconditioning, [RefSeq, PubMed]; MK2 small interfering RNA delivery arrests lipopolysaccharide-induced inflammatory bone loss, decreases inflammatory infiltrate, and decreases osteoclastogenesis., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, 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"https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.7.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.34", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" }, { "id": "1.13.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.13.11.-", "type": "external" }, { "id": "1.13.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:1.13.11.34", "type": "external" }, { "id": "2.7.11.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.19", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.11.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.4", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.4.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.18", "type": "external" }, { "id": "3.1.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.24.-", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" } ], "go_molecular_function": "GO:0009931 calcium-dependent protein serine/threonine kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0051019 mitogen-activated protein kinase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0006468 protein phosphorylation;GO:0006954 inflammatory response;GO:0032496 response to lipopolysaccharide;GO:0035556 intracellular signal transduction;GO:0048255 mRNA stabilization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q80ZF4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JZJ1-1", "uniprot_id": [ { "id": "A0A0G2JZJ1_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JZJ1", "type": "external" } ], "mass": 34577.0, "length": 310, "protein_name": "Ubiquitin C-terminal hydrolase PSMD14", "gene_name": "Psmd14", "organism": "Rat", "refseq_name": "26S proteasome non-ATPase regulatory subunit 14", "refseq_ac": [ { "id": "NP_001020860", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020860", "type": "external" } ], "gene_names_uniprotkb": "Psmd14", "gene_names_refseq": "Psmd14", "protein_names_uniprotkb": "Ubiquitin C-terminal hydrolase PSMD14; 26S Proteasome regulatory subunit RPN11; 26S proteasome non-ATPase regulatory subunit 14", "protein_names_refseq": "26S proteasome non-ATPase regulatory subunit 14; proteasome (prosome, macropain) 26S subunit, non-ATPase, 14", "tax_id": 10116, "disease": "alcohol-associated liver disease (Disease Ontology:DOID:0070658)", "pathway": " (rno:311078)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "17329080;29398115;33609735", "class_list": "", "function": "Males and females differ in the regulation and engagement of, but not requirement for, protein degradation in the amygdala during fear memory formation., [RefSeq, PubMed]; Translocation from synapse to the nucleus is involved in regulation of Tbr-1 function in postnatal and adult brains, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A6HLU7;F1LMW6;Q4V8E2", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0061133 endopeptidase activator activity;GO:0070628 proteasome binding;GO:0061578 K63-linked deubiquitinase activity;GO:0140492 metal-dependent deubiquitinase activity", "go_cellular_component": "GO:0031597 cytosolic proteasome complex;GO:0022624 proteasome accessory complex;GO:0005654 nucleoplasm;GO:0000502 proteasome complex;GO:0008541 proteasome regulatory particle, lid subcomplex", "go_biological_process": "GO:0006508 proteolysis;GO:0045471 response to ethanol;GO:0070536 protein K63-linked deubiquitination;GO:0016241 regulation of macroautophagy;GO:0006303 double-strand break repair via nonhomologous end joining", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2JZJ1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K6F4-1", "uniprot_id": [ { "id": "A0A0G2K6F4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K6F4", "type": "external" } ], "mass": 101657.0, "length": 894, "protein_name": "Exostosin-like 3", "gene_name": "Extl3", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Extl3", "gene_names_refseq": "", "protein_names_uniprotkb": "Exostosin-like 3; 2.4.1.223; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Multiple exostosis-like protein 3", "protein_names_refseq": "", "tax_id": 10116, "disease": "hereditary multiple exostoses (Disease Ontology:DOID:206)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Glycosyltransferase which regulates the biosynthesis of heparan sulfate (HS). Initiates HS synthesis by transferring the first N-acetyl-alpha-D-glucosamine (alpha-GlcNAc) residue (GlcNAcT-I activity) to the tetrasaccharide linker (GlcA-Gal-Gal-Xyl-)Ser core linker. May also transfer alpha-GlcNAc residues during HS elongation (GlcNAcT-II activity). Lacks glucuronyl transferase II (GlcAT-II) activity. Important for both skeletal development and hematopoiesis, through the formation of HS proteoglycans (HSPGs). Through the synthesis of HS, regulates postnatal pancreatic islet maturation and insulin secretion., [UniProtKB, UniProtKB]; Receptor for REG3A, REG3B and REG3G, induces the activation of downstream signaling pathways such as PI3K-AKT or RAS-RAF-MEK-ERK signaling pathway. Required for the function of REG3A in regulating keratinocyte proliferation and differentiation. Required for the inhibition of skin inflammation mediated by REG3A through the activation of PI3K-AKT-STAT3 pathway. Required for the function of REG3A and REG3G in glucose tolerance in pancreas. 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Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction. As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest. As part of a ribonucleoprotein complex composed at least of ZNF827, HNRNPL and the circular RNA circZNF827 that nucleates the complex on chromatin, may negatively regulate the transcription of genes involved in neuronal differentiation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003729 mRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005681 spliceosomal complex;GO:0002102 podosome", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006397 mRNA processing;GO:0010629 negative regulation of gene expression;GO:0008380 RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I5ZZG4-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A072-1", "uniprot_id": [ { "id": "A0A8I6A072_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A072", "type": "external" } ], "mass": 26427.0, "length": 237, "protein_name": "Rab-like protein 3", "gene_name": "Rabl3", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Rabl3", "gene_names_refseq": "", "protein_names_uniprotkb": "Rab-like protein 3; 3.6.5.2", "protein_names_refseq": "", "tax_id": 10116, "disease": "pancreatic cancer (Disease Ontology:DOID:1793)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Small GTPase required for KRAS signaling regulation and modulation of cell proliferation. Regulator of KRAS prenylation, and probably prenylation of other small GTPases. Required for lymphocyte development and function. Not required for myeloid cell development. Interacts with Rab11 to promote ciliary vesicle formation at the mother centriole, thereby regulating early ciliogenesis. The GTP-binding capacity of RABL3 is essential for ciliogenesis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, 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positive regulation of mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6A079-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A1G6-1", "uniprot_id": [ { "id": "A0A8I6A1G6_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A1G6", "type": "external" } ], "mass": 40558.0, "length": 372, "protein_name": "Regulatory factor X-associated ankyrin-containing protein", "gene_name": "Rfxank", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Rfxank", "gene_names_refseq": "", "protein_names_uniprotkb": "Regulatory factor X-associated ankyrin-containing protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "severe combined immunodeficiency (Disease Ontology:DOID:627)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", 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0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042826 histone deacetylase binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0090575 RNA polymerase II transcription regulator complex", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007265 Ras protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6A1G6-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A3R0-1", "uniprot_id": [ { "id": "A0A8I6A3R0_RAT", "url": 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"reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005925 focal adhesion;GO:0015629 actin cytoskeleton;GO:0030027 lamellipodium", "go_biological_process": "GO:0030036 actin cytoskeleton organization;GO:0030032 lamellipodium assembly;GO:0034446 substrate adhesion-dependent cell spreading;GO:0071963 establishment or maintenance of cell polarity regulating cell shape;GO:0030031 cell projection assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KB09-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AHX2-1", "uniprot_id": [ { "id": "A0A8I6AHX2_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AHX2", "type": "external" } ], "mass": 267485.0, "length": 2430, "protein_name": "Telomere-associated protein RIF1", "gene_name": "Rif1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Rif1", "gene_names_refseq": "", "protein_names_uniprotkb": "Telomere-associated protein RIF1; Rap1-interacting factor 1 homolog", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-5693571)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Key regulator of TP53BP1 that plays a key role in the repair of double-strand DNA breaks (DSBs) in response to DNA damage: acts by promoting non-homologous end joining (NHEJ)-mediated repair of DSBs. In response to DNA damage, interacts with ATM-phosphorylated TP53BP1. Interaction with TP53BP1 leads to dissociate the interaction between NUDT16L1/TIRR and TP53BP1, thereby unmasking the tandem Tudor-like domain of TP53BP1 and allowing recruitment to DNA DSBs. Once recruited to DSBs, RIF1 and TP53BP1 act by promoting NHEJ-mediated repair of DSBs. In the same time, RIF1 and TP53BP1 specifically counteract the function of BRCA1 by blocking DSBs resection via homologous recombination (HR) during G1 phase. Also required for immunoglobulin class-switch recombination (CSR) during antibody genesis, a process that involves the generation of DNA DSBs. Promotes NHEJ of dysfunctional telomeres., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 1, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0000781 chromosome, telomeric region;GO:0005819 spindle;GO:0035861 site of double-strand break;GO:0005654 nucleoplasm", "go_biological_process": "GO:2000042 negative regulation of double-strand break repair via homologous recombination;GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining;GO:0006281 DNA repair;GO:0000723 telomere maintenance;GO:0031509 subtelomeric heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I6AHX2-1", "record_type": "protein", "filter_code": "0000000.1000101.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZT67-1", "uniprot_id": [ { "id": "A0A8I5ZT67_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZT67", "type": "external" } ], "mass": 86259.0, "length": 744, "protein_name": "Zinc finger protein 120 like 1", "gene_name": "Zfp120l1", "organism": "Rat", "refseq_name": "zinc finger protein 431-like isoform X1", "refseq_ac": [ { "id": "XP_038938713", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038938713", "type": "external" } ], "gene_names_uniprotkb": "Zfp120l1; LOC102555317", "gene_names_refseq": "Zfp120l1", "protein_names_uniprotkb": "Zinc finger protein 120 like 1", "protein_names_refseq": "zinc finger protein 431-like isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:102555317)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0003700 DNA-binding transcription factor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I5ZT67-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AFP3-1", "uniprot_id": [ { "id": "A0A8I6AFP3_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AFP3", "type": "external" } ], "mass": 129301.0, "length": 1129, "protein_name": "Phospholipid-transporting ATPase", "gene_name": "Atp11c", "organism": "Rat", "refseq_name": "ATPase phospholipid transporting 11C isoform 1", "refseq_ac": [ { "id": "NP_001419934", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001419934", "type": "external" } ], "gene_names_uniprotkb": "Atp11c", "gene_names_refseq": "Atp11c-ps1; Atp11c; RGD1564481", "protein_names_uniprotkb": "Phospholipid-transporting ATPase; 7.6.2.1", "protein_names_refseq": "ATPase phospholipid transporting 11C isoform 1; ATPase, class VI, type 11C, pseudogene 1; phospholipid-transporting ATPase IG", "tax_id": 10116, "disease": "X-linked congenital hemolytic anemia (Disease Ontology:DOID:0111846)", "pathway": " (R-RNO-936837)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids, phosphatidylserines (PS) and phosphatidylethanolamines (PE), from the outer to the inner leaflet of the plasma membrane. Major PS-flippase in immune cell subsets. In erythrocyte plasma membrane, it is required to maintain PS in the inner leaflet preventing its exposure on the surface. This asymmetric distribution is critical for the survival of erythrocytes in circulation since externalized PS is a phagocytic signal for erythrocyte clearance by splenic macrophages. Required for B cell differentiation past the pro-B cell stage. Seems to mediate PS flipping in pro-B cells. May be involved in the transport of cholestatic bile acids., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "7.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.1", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0090555 phosphatidylethanolamine flippase activity;GO:0140326 ATPase-coupled intramembrane lipid transporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0055037 recycling endosome;GO:1990531 phospholipid-translocating ATPase complex;GO:0016020 membrane", "go_biological_process": "GO:0045332 phospholipid translocation;GO:0002329 pre-B cell differentiation;GO:0045579 positive regulation of B cell differentiation;GO:0015914 phospholipid transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I6AFP3-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6GMR5-1", "uniprot_id": [ { "id": "A0A8I6GMR5_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6GMR5", "type": "external" } ], "mass": 101479.0, "length": 855, "protein_name": "RNA-binding protein 25", "gene_name": "Rbm25l1; Rbm25", "organism": "Rat", "refseq_name": "RNA-binding protein 25 isoform X1", "refseq_ac": [ { "id": "XP_038968572", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038968572", "type": "external" } ], "gene_names_uniprotkb": "Rbm25l1; Rbm25; Rbm25l1", "gene_names_refseq": "Rbm25", "protein_names_uniprotkb": "RNA-binding protein 25; RNA-binding motif protein 25", "protein_names_refseq": "RNA-binding protein 25 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:497865); (R-RNO-9770562)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016607 nuclear speck", "go_biological_process": "GO:0000381 regulation of alternative mRNA splicing, via spliceosome;GO:0006397 mRNA processing;GO:0008380 RNA splicing;GO:0042981 regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6GMR5-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A567-1", "uniprot_id": [ { "id": "A0A8I6A567_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A567", "type": "external" } ], "mass": 266986.0, "length": 2439, "protein_name": "SEH1-like nucleoporin", "gene_name": "Cep192; Seh1l", "organism": "Rat", "refseq_name": "centrosomal protein of 192 kDa isoform X3", "refseq_ac": [ { "id": "XP_063133382", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063133382", "type": "external" } ], "gene_names_uniprotkb": "Cep192; Seh1l; Seh1l", "gene_names_refseq": "Cep192; Da1-6; Seh1l", "protein_names_uniprotkb": "SEH1-like nucleoporin", "protein_names_refseq": "centrosomal protein of 192 kDa isoform X3", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-2565942); (R-RNO-380259); (R-RNO-380270); (R-RNO-380284); (R-RNO-380320); (R-RNO-5620912); (R-RNO-8854518)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "As a component of the GATOR2 complex, functions as an activator of the amino acid-sensing branch of the mTORC1 signaling pathway. The GATOR2 complex indirectly activates mTORC1 through the inhibition of the GATOR1 subcomplex. GATOR2 probably acts as an E3 ubiquitin-protein ligase toward GATOR1. In the presence of abundant amino acids, the GATOR2 complex mediates ubiquitination of the NPRL2 core component of the GATOR1 complex, leading to GATOR1 inactivation. In the absence of amino acids, GATOR2 is inhibited, activating the GATOR1 complex. Within the GATOR2 complex, SEC13 and SEH1L are required to stabilize the complex., [UniProtKB, UniProtKB, UniProtKB]; Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity;GO:0019902 phosphatase binding", "go_cellular_component": "GO:0031080 nuclear pore outer ring;GO:0005635 nuclear envelope;GO:0005765 lysosomal membrane;GO:0000776 kinetochore;GO:0061700 GATOR2 complex", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0051315 attachment of mitotic spindle microtubules to kinetochore;GO:0006999 nuclear pore organization;GO:0015031 protein transport;GO:0050830 defense response to Gram-positive bacterium", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I6A567-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AJW7-1", "uniprot_id": [ { "id": "A0A8I6AJW7_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AJW7", "type": "external" } ], "mass": 35317.0, "length": 316, "protein_name": "Olfactory receptor family 2 subfamily AG member 19", "gene_name": "Or2ag19b", "organism": "Rat", "refseq_name": "olfactory receptor Olr214", "refseq_ac": [ { "id": "NP_001000197", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000197", "type": "external" } ], "gene_names_uniprotkb": "Or2ag19b; Or2ag19", "gene_names_refseq": "Olr214; Or2ag19", "protein_names_uniprotkb": "Olfactory receptor family 2 subfamily AG member 19", "protein_names_refseq": "olfactory receptor 214; olfactory receptor Olr214; olfactory receptor gene Olr214", "tax_id": 10116, "disease": "", "pathway": " (rno:293361); (rno:405392)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "M0RDA9", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6AJW7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZUI1-1", "uniprot_id": [ { "id": "A0A8I5ZUI1_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZUI1", "type": "external" } ], "mass": 62213.0, "length": 557, "protein_name": "Ras-specific guanine nucleotide-releasing factor RalGPS1", "gene_name": "Ralgps1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ralgps1", "gene_names_refseq": "", "protein_names_uniprotkb": "Ras-specific guanine nucleotide-releasing factor RalGPS1; 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4.3.2.2; ASL; Adenylosuccinase", "protein_names_refseq": "adenylosuccinate lyase", "tax_id": 10116, "disease": "adenylosuccinase lyase deficiency (Disease Ontology:DOID:0050762); prostate cancer (Disease Ontology:DOID:10283); breast cancer (Disease Ontology:DOID:1612)", "pathway": " (rno:315150); (R-RNO-73817)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.3.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:4.3.2.2", "type": "external" } ], "go_molecular_function": "GO:0016829 lyase activity;GO:0042802 identical protein binding;GO:0004018 N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity;GO:0070626 (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity", "go_cellular_component": "GO:0005829 cytosol;GO:0032991 protein-containing complex", "go_biological_process": "GO:0007584 response to nutrient;GO:0042594 response to starvation;GO:0001666 response to hypoxia;GO:0014850 response to muscle activity;GO:0006177 GMP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I5ZTN5-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6GAY3-1", "uniprot_id": [ { "id": "A0A8I6GAY3_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6GAY3", "type": "external" } ], "mass": 20732.0, "length": 196, "protein_name": "Guanine nucleotide-binding protein subunit gamma", "gene_name": "Gng12", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Gng12", "gene_names_refseq": "", "protein_names_uniprotkb": "Guanine nucleotide-binding protein subunit gamma", "protein_names_refseq": "", "tax_id": 10116, "disease": "obesity (Disease Ontology:DOID:9970)", "pathway": " (rno:114120); (R-RNO-1296041); (R-RNO-202040); (R-RNO-381676); (R-RNO-392170); (R-RNO-392451); (R-RNO-400042); (R-RNO-4086398); (R-RNO-416476); (R-RNO-418594); (R-RNO-418597); (R-RNO-420092); (R-RNO-428930); (R-RNO-432040); (R-RNO-456926); (R-RNO-8964616); (R-RNO-9856530); (R-RNO-997272)", "pathway_count": 18, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042301 phosphate ion binding;GO:0031681 G-protein beta-subunit binding;GO:0030165 PDZ domain binding", "go_cellular_component": "GO:0005884 actin filament;GO:0045202 synapse;GO:0005834 heterotrimeric G-protein complex", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0032496 response to lipopolysaccharide;GO:0021987 cerebral cortex development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I6GAY3-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AV25-1", "uniprot_id": [ { "id": "A0A8I6AV25_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AV25", "type": "external" } ], "mass": 21328.0, "length": 195, "protein_name": "Zinc finger, SWIM-type containing 7", "gene_name": "Zswim7", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Zswim7", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger, SWIM-type containing 7", "protein_names_refseq": "", "tax_id": 10116, "disease": "ovarian dysgenesis 10 (Disease Ontology:DOID:0061014); 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5.2.1.8; PPIase", "protein_names_refseq": "peptidyl-prolyl cis-trans isomerase C precursor; peptidyl-prolyl cis-trans isomerase C", "tax_id": 10116, "disease": "", "pathway": " (rno:291463)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding., [UniProtKB, UniProtKB]; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0016018 cyclosporin A binding;GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F7FHM1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AU47-1", "uniprot_id": [ { "id": "A0A8I6AU47_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AU47", "type": "external" } ], "mass": 35782.0, "length": 314, "protein_name": "Olfactory receptor", "gene_name": "Or6c6b; Or6c6f; Or6c6h; Or6c6i", "organism": "Rat", "refseq_name": "olfactory receptor Olr951", "refseq_ac": [ { "id": "NP_001000073", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000073", "type": "external" } ], "gene_names_uniprotkb": "Or6c6b; Or6c6f; Or6c6h; Or6c6i; Olr951; Olr962; Or6c6b; Or6c6h; Or6c6i", "gene_names_refseq": "Olr951; ratchr7-4859164-4858220_ORF", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor Olr951; olfactory receptor gene Olr951", "tax_id": 10116, "disease": "", "pathway": " (rno:288810); (rno:288879); (rno:288887); (rno:302045); (rno:404948)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6AU47-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AHA3-1", "uniprot_id": [ { "id": "A0A8I6AHA3_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AHA3", "type": "external" } ], "mass": 53361.0, "length": 471, "protein_name": "Methyltransferase 4, N6-adenosine", "gene_name": "Mettl4", "organism": "Rat", "refseq_name": "N(6)-adenine-specific methyltransferase METTL4", "refseq_ac": [ { "id": "NP_001178743", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178743", "type": "external" } ], "gene_names_uniprotkb": "Mettl4", "gene_names_refseq": "Mettl4; RGD1306451", "protein_names_uniprotkb": "Methyltransferase 4, N6-adenosine", "protein_names_refseq": "N(6)-adenine-specific methyltransferase METTL4; methyltransferase like 4; methyltransferase-like protein 4", "tax_id": 10116, "disease": "", "pathway": " (rno:316731)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "33992834", "class_list": "", "function": "METTL3/METTL14 Transactivation and m(6)A-Dependent TGF-beta1 Translation in Activated Kupffer Cells., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, 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N6-methyladenosine methyltransferase complex;GO:0005829 cytosol;GO:0005634 nucleus;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0032259 methylation;GO:0043484 regulation of RNA splicing;GO:0045814 negative regulation of gene expression, epigenetic;GO:0090296 regulation of mitochondrial DNA replication;GO:0120049 snRNA (adenine-N6)-methylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I6AHA3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AN76-1", "uniprot_id": [ { "id": "A0A8I6AN76_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AN76", "type": "external" } ], "mass": 122754.0, "length": 1078, "protein_name": "WD repeat domain 64", "gene_name": "Wdr64", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Wdr64", "gene_names_refseq": "", "protein_names_uniprotkb": "WD repeat domain 64", 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"refseq_ac": [ { "id": "XP_008759682", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008759682", "type": "external" } ], "gene_names_uniprotkb": "Cdc14a", "gene_names_refseq": "Cdc14a", "protein_names_uniprotkb": "Cell division cycle 14A", "protein_names_refseq": "dual specificity protein phosphatase CDC14A isoform X2", "tax_id": 10116, "disease": "autosomal recessive nonsyndromic deafness 32 (Disease Ontology:DOID:0110491)", "pathway": " (R-RNO-176407); (R-RNO-5687128)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Dual-specificity phosphatase. Required for centrosome separation and productive cytokinesis during cell division. Dephosphorylates SIRT2 around early anaphase. May dephosphorylate the APC subunit FZR1/CDH1, thereby promoting APC-FZR1 dependent degradation of mitotic cyclins and subsequent exit from mitosis. Required for normal hearing., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.53", "type": "external" }, { "id": "3.1.3.52", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.52", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "3.1.3.74", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.74", "type": "external" } ], "go_molecular_function": "GO:0004722 protein serine/threonine phosphatase activity;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0000922 spindle pole;GO:0005654 nucleoplasm;GO:0005813 centrosome;GO:0060091 kinocilium;GO:0032426 stereocilium tip", "go_biological_process": "GO:0051301 cell division;GO:0007605 sensory perception of sound;GO:0060271 cilium assembly;GO:0000226 microtubule cytoskeleton organization;GO:0007096 regulation of exit from mitosis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6B415-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6GAW9-1", "uniprot_id": [ { "id": "A0A8I6GAW9_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6GAW9", "type": "external" } ], "mass": 155424.0, "length": 1388, "protein_name": "Ubiquitin conjugation factor E4", "gene_name": "Ube4b", "organism": "Rat", "refseq_name": "ubiquitin conjugation factor E4 B isoform X1", "refseq_ac": [ { "id": "XP_006239449", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006239449", "type": "external" } ], "gene_names_uniprotkb": "Ube4b", "gene_names_refseq": "Ube4b; ufd2a", "protein_names_uniprotkb": "Ubiquitin conjugation factor E4; 2.3.2.27; RING-type E3 ubiquitin transferase E4", "protein_names_refseq": "ubiquitin conjugation factor E4 B isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:298652)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. Also functions as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. Mediates 'Lys-48'-linked polyubiquitination of substrates., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0019899 enzyme binding;GO:0051117 ATPase binding;GO:0061630 ubiquitin protein ligase activity;GO:0034450 ubiquitin-ubiquitin ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000151 ubiquitin ligase complex", "go_biological_process": "GO:0031175 neuron projection development;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0009411 response to UV;GO:0016567 protein ubiquitination;GO:0000209 protein polyubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I6GAW9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A5D5-1", "uniprot_id": [ { "id": "A0A8I6A5D5_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A5D5", "type": "external" } ], "mass": 93967.0, "length": 853, "protein_name": "SH2 domain containing 3C", "gene_name": "Sh2d3c", "organism": "Rat", "refseq_name": "SH2 domain-containing protein 3C", "refseq_ac": [ { "id": "NP_001102049", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102049", "type": "external" } ], "gene_names_uniprotkb": "Sh2d3c", "gene_names_refseq": "NSP3; Sh2d3c", "protein_names_uniprotkb": "SH2 domain containing 3C", "protein_names_refseq": "SH2 domain-containing protein 3C", "tax_id": 10116, "disease": "", "pathway": " (rno:362111)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "22673903;29966723", "class_list": "", "function": "NSP3 RNAi knock-down partially rescued amyloid-Beta-oligomer-treated neurons., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001784 phosphotyrosine residue binding;GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0007264 small GTPase-mediated signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8I6A5D5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AHB5-1", "uniprot_id": [ { "id": "A0A8I6AHB5_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AHB5", "type": "external" } ], "mass": 61057.0, "length": 544, "protein_name": "BBSome complex member BBS4", "gene_name": "Bbs4", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Bbs4", "gene_names_refseq": "", "protein_names_uniprotkb": "BBSome complex member BBS4", "protein_names_refseq": "", "tax_id": 10116, "disease": "Bardet-Biedl syndrome 4 (Disease Ontology:DOID:0110126); morbid obesity (Disease Ontology:DOID:11981); Bardet-Biedl syndrome (Disease Ontology:DOID:1935); obesity (Disease Ontology:DOID:9970)", "pathway": " (rno:300754); (R-RNO-5620922)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0048487 beta-tubulin binding;GO:0043014 alpha-tubulin binding;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding;GO:0034452 dynactin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0005929 cilium;GO:0016020 membrane;GO:0031514 motile cilium", "go_biological_process": "GO:0002260 lymphocyte homeostasis;GO:0010629 negative regulation of gene expression;GO:0016358 dendrite development;GO:0030534 adult behavior;GO:0060612 adipose tissue development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6AHB5-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6APB9-1", "uniprot_id": [ { "id": "A0A8I6APB9_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6APB9", "type": "external" } ], "mass": 34297.0, "length": 310, "protein_name": "PAK4-inhibitor INKA2", "gene_name": "Inka2", "organism": "Rat", "refseq_name": "PAK4-inhibitor INKA2 isoform X1", "refseq_ac": [ { "id": "XP_006233150", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006233150", "type": "external" } ], "gene_names_uniprotkb": "Inka2; Fam212b", "gene_names_refseq": "Fam212b; Inka2; RGD1306526", "protein_names_uniprotkb": "PAK4-inhibitor INKA2; Induced in neural crest by AP2-alpha protein-related homolog; PAK4-inhibitor inka2", "protein_names_refseq": "PAK4-inhibitor INKA2 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:310764)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Inhibitor of the serine/threonine-protein kinase PAK4. Acts by binding PAK4 in a substrate-like manner, inhibiting the protein kinase activity., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0030291 protein serine/threonine kinase inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6APB9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6APS9-1", "uniprot_id": [ { "id": "A0A8I6APS9_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6APS9", "type": "external" } ], "mass": 115999.0, "length": 1078, "protein_name": "Ankyrin repeat domain 28", "gene_name": "Ankrd28", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ankrd28", "gene_names_refseq": "", "protein_names_uniprotkb": "Ankyrin repeat domain 28", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:306264); (R-RNO-171319); (R-RNO-204005)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019888 protein phosphatase regulator activity", "go_cellular_component": "GO:0005829 cytosol;GO:0030027 lamellipodium;GO:0008287 protein serine/threonine phosphatase complex;GO:0005654 nucleoplasm", "go_biological_process": "GO:0051894 positive regulation of focal adhesion assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6APS9-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6GL93-1", "uniprot_id": [ { "id": "A0A8I6GL93_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6GL93", "type": "external" } ], "mass": 85810.0, "length": 733, "protein_name": "Solute carrier family 53 member 1", "gene_name": "Xpr1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Xpr1", "gene_names_refseq": "", "protein_names_uniprotkb": "Solute carrier family 53 member 1; Phosphate exporter SLC53A1", "protein_names_refseq": "", "tax_id": 10116, "disease": "basal ganglia calcification (Disease Ontology:DOID:0060230)", "pathway": " (rno:289424)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Inorganic ion transporter that mediates phosphate ion export across the plasma membrane. Plays a major role in phosphate homeostasis, preventing intracellular phosphate accumulation and possible calcium phosphate precipitation, ultimately preserving calcium signaling. Binds inositol hexakisphosphate (Ins6P) and similar inositol polyphosphates, such as 5-diphospho-inositol pentakisphosphate (5-InsP7), which are important intracellular signaling molecules involved in regulation of phosphate flux., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001618 virus receptor activity;GO:0015562 efflux transmembrane transporter activity;GO:0005315 phosphate transmembrane transporter activity;GO:0000822 inositol hexakisphosphate binding", "go_cellular_component": "GO:0016020 membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0009615 response to virus;GO:0035435 phosphate ion transmembrane transport;GO:0030643 intracellular phosphate ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6GL93-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8L2QL41-1", "uniprot_id": [ { "id": "A0A8L2QL41_RAT", "url": "https://www.uniprot.org/uniprot/A0A8L2QL41", "type": "external" } ], "mass": 62603.0, "length": 561, "protein_name": "Carboxylic ester hydrolase", "gene_name": "Ces2f", "organism": "Rat", "refseq_name": "acylcarnitine hydrolase-like", "refseq_ac": [ { "id": "XP_038954070", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038954070", "type": "external" } ], "gene_names_uniprotkb": "Ces2f; 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zinc transporter ZIP10", "tax_id": 10116, "disease": "", "pathway": " (rno:363229)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "22673903;33742346;38843836", "class_list": "", "function": "Chronic Running Exercise Regulates Cytotoxic Cell Functions and Zinc Transporter SLC39A10/ZIP10 Levels in Diabetic Rats., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005385 zinc ion transmembrane transporter activity;GO:0008160 protein tyrosine phosphatase activator activity;GO:0140410 monoatomic cation:bicarbonate symporter activity", "go_cellular_component": "GO:0016324 apical plasma membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0001837 epithelial to mesenchymal transition;GO:0071577 zinc ion transmembrane transport;GO:0030890 positive regulation of B cell proliferation;GO:0006882 intracellular zinc ion homeostasis;GO:0030003 intracellular monoatomic cation homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A1W2Q626-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0100000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6G5Q1-1", "uniprot_id": [ { "id": "A0A8I6G5Q1_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6G5Q1", "type": "external" } ], "mass": 95817.0, "length": 862, "protein_name": "Semaphorin-4D", "gene_name": "Sema4d", "organism": "Rat", "refseq_name": "semaphorin-4D precursor", "refseq_ac": [ { "id": "NP_001164034", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001164034", "type": "external" } ], "gene_names_uniprotkb": "Sema4d", "gene_names_refseq": "Sema4d", "protein_names_uniprotkb": "Semaphorin-4D", "protein_names_refseq": "sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D; semaphorin-4D precursor", "tax_id": 10116, "disease": "", "pathway": " (rno:306790); (R-RNO-416550); (R-RNO-416572); (R-RNO-416700)", "pathway_count": 4, "publication_count": 6, "publication_id_list": "22673903;24549858;26489627;28624895;36970799;38843836", "class_list": "", "function": "Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling. Regulates GABAergic synapse development. Promotes the development of inhibitory synapses in a PLXNB1-dependent manner. Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA. Promotes the migration of cerebellar granule cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Induces endothelial cell migration through the activation of PTK2B/PYK2, SRC, and the phosphatidylinositol 3-kinase-AKT pathway., [UniProtKB, UniProtKB, UniProtKB]; Sema4D knockdown in OPCs inhibited wound tissue angiogenesis and inflammation genes expression and upregulated axon regeneration genes expression at early phase, [RefSeq, PubMed]; Skeletal fluorosis in vitro is caused by inhibition of osteogenesis via Sema4D/Plexin-B1 signaling pathway., [RefSeq, PubMed]; These results demonstrate a novel physiological function for sema4D/plxnB1 signaling in retinal pigment epithelium phagocytosis., [RefSeq, PubMed]; [The role of semaphorin 4D in the mechanism of bisphosphonate-related osteonecrosis of the jaw in rats]., [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030215 semaphorin receptor binding;GO:0004888 transmembrane signaling receptor activity;GO:0005102 signaling receptor binding;GO:0042802 identical protein binding;GO:0038191 neuropilin binding", "go_cellular_component": "GO:0016020 membrane;GO:0098982 GABA-ergic synapse;GO:0002116 semaphorin receptor complex;GO:0005615 extracellular space;GO:0005886 plasma membrane", "go_biological_process": "GO:0007399 nervous system development;GO:0030154 cell differentiation;GO:0120035 regulation of plasma membrane bounded cell projection organization;GO:0031344 regulation of cell projection organization;GO:0043931 ossification involved in bone maturation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A8I6G5Q1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0100000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6ANV3-1", "uniprot_id": [ { "id": "A0A8I6ANV3_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6ANV3", "type": "external" } ], "mass": 252942.0, "length": 2363, "protein_name": "Neuron navigator 3", "gene_name": "Nav3", "organism": "Rat", "refseq_name": "neuron navigator 3 isoform X1", "refseq_ac": [ { "id": "XP_038935037", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038935037", "type": "external" } ], "gene_names_uniprotkb": "Nav3", "gene_names_refseq": "Nav3; RGD1306259", "protein_names_uniprotkb": "Neuron navigator 3; Pore membrane and/or filament-interacting-like protein 1", "protein_names_refseq": "neuron navigator 3 isoform X1", "tax_id": 10116, "disease": "cerebellar hypoplasia (Disease Ontology:DOID:0070338); opiate dependence (Disease Ontology:DOID:2559)", "pathway": " (rno:314814)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "38843836", "class_list": "", "function": "Is involved in microtubule cytoskeleton organization and plays a role in cell migration., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0008017 microtubule binding", "go_cellular_component": "GO:0005640 nuclear outer membrane;GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005874 microtubule;GO:1990752 microtubule end", "go_biological_process": "GO:0022008 neurogenesis;GO:0032703 negative regulation of interleukin-2 production;GO:0007399 nervous system development;GO:0030336 negative regulation of cell migration;GO:0007026 negative regulation of microtubule depolymerization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A8I6ANV3-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0100000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6GCQ3-1", "uniprot_id": [ { "id": "A0A8I6GCQ3_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6GCQ3", "type": "external" } ], "mass": 123447.0, "length": 1101, "protein_name": "Anoctamin", "gene_name": "Ano8", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ano8", "gene_names_refseq": "", "protein_names_uniprotkb": "Anoctamin", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-2672351); (R-RNO-381426); (R-RNO-8957275)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005229 intracellularly calcium-gated chloride channel activity", "go_cellular_component": "GO:0016020 membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:1902476 chloride transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I6GCQ3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AWM3-1", "uniprot_id": [ { "id": "A0A8I6AWM3_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AWM3", "type": "external" } ], "mass": 268025.0, "length": 2329, "protein_name": "Spectrin beta chain", "gene_name": "Sptb", "organism": "Rat", "refseq_name": "spectrin beta chain, erythrocytic isoform 2", "refseq_ac": [ { "id": "NP_001420901", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001420901", "type": "external" } ], "gene_names_uniprotkb": "Sptb", "gene_names_refseq": "Spnb1; Sptb", "protein_names_uniprotkb": "Spectrin beta chain", "protein_names_refseq": "erythroid spectrin beta; spectrin beta 1; spectrin beta chain, erythrocyte; spectrin beta chain, erythrocytic isoform 2; spectrin beta chain, erythrocytic", "tax_id": 10116, "disease": "spinocerebellar ataxia 5 (Disease Ontology:DOID:0050882); hereditary spherocytosis type 2 (Disease Ontology:DOID:0110917); hereditary spherocytosis (Disease Ontology:DOID:12971)", "pathway": " (R-RNO-375165); (R-RNO-445095); (R-RNO-5673001); (R-RNO-6807878)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "21297961;22673903", "class_list": "", "function": "Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Suggest that betaI-spectrin is a synaptic protein that can modulate both the morphological and functional dynamics of dendritic spines, perhaps via interaction with actin and Rac3. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0005200 structural constituent of cytoskeleton;GO:0005543 phospholipid binding;GO:0051015 actin filament binding;GO:0030506 ankyrin binding", "go_cellular_component": "GO:0016020 membrane;GO:0008091 spectrin;GO:0098978 glutamatergic synapse;GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0051693 actin filament capping;GO:0098885 modification of postsynaptic actin cytoskeleton;GO:0007009 plasma membrane organization;GO:0030036 actin cytoskeleton organization;GO:0030097 hemopoiesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8I6AWM3-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6B1B9-1", "uniprot_id": [ { "id": "A0A8I6B1B9_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6B1B9", "type": "external" } ], "mass": 223906.0, "length": 1996, "protein_name": "Leucine-rich repeat serine/threonine-protein kinase 1", "gene_name": "Lrrk1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Lrrk1", "gene_names_refseq": "", "protein_names_uniprotkb": "Leucine-rich repeat serine/threonine-protein kinase 1; 2.7.11.1", "protein_names_refseq": "", "tax_id": 10116, "disease": "Parkinson's disease 8 (Disease Ontology:DOID:0060371); late onset Parkinson's disease (Disease Ontology:DOID:0060892); osteosclerotic metaphyseal dysplasia (Disease Ontology:DOID:0081111); osteopetrosis (Disease Ontology:DOID:13533); Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (R-RNO-2672351)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Serine/threonine-protein kinase which phosphorylates RAB proteins involved in intracellular trafficking. Phosphorylates RAB7A; this activity is dependent on protein kinase C (PKC) activation. 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0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": 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"2.7.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.34", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "2.7.11.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.19", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" 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"external" } ], "mass": 94738.0, "length": 849, "protein_name": "Round spermatid basic protein 1-like", "gene_name": "Rsbn1l", "organism": "Rat", "refseq_name": "lysine-specific demethylase RSBN1L isoform X1", "refseq_ac": [ { "id": "XP_063142027", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063142027", "type": "external" } ], "gene_names_uniprotkb": "Rsbn1l", "gene_names_refseq": "RGD1308748; Rsbn1l", "protein_names_uniprotkb": "Round spermatid basic protein 1-like", "protein_names_refseq": "lysine-specific demethylase RSBN1L isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:311987)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, 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"ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005794 Golgi apparatus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I6AS17-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6ASC6-1", "uniprot_id": [ { "id": "A0A8I6ASC6_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6ASC6", "type": "external" } ], "mass": 134702.0, "length": 1253, "protein_name": "Immunoglobulin superfamily DCC subclass member 4", "gene_name": "Igdcc4", "organism": "Rat", "refseq_name": "immunoglobulin superfamily DCC subclass member 4 isoform 2 precursor", "refseq_ac": [ { "id": "NP_001402636", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001402636", "type": "external" } ], "gene_names_uniprotkb": "Igdcc4", "gene_names_refseq": "Igdcc4; Nope", "protein_names_uniprotkb": "Immunoglobulin 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0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050768 negative regulation of neurogenesis;GO:0098609 cell-cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A8I6ASC6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AR85-1", "uniprot_id": [ { "id": "A0A8I6AR85_RAT", "url": 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cerebrooculofacioskeletal syndrome 4 (Disease Ontology:DOID:0080914); stomach cancer (Disease Ontology:DOID:10534); kidney failure (Disease Ontology:DOID:1074); azoospermia (Disease Ontology:DOID:14227); alcohol use disorder (Disease Ontology:DOID:1574); breast cancer (Disease Ontology:DOID:1612); pancreatic cancer (Disease Ontology:DOID:1793); ovary epithelial cancer (Disease Ontology:DOID:2152); transient cerebral ischemia (Disease Ontology:DOID:224); anemia (Disease Ontology:DOID:2355); ovarian cancer (Disease Ontology:DOID:2394); high grade glioma (Disease Ontology:DOID:3070); osteosarcoma (Disease Ontology:DOID:3347); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung carcinoma (Disease Ontology:DOID:3905); lung non-small cell carcinoma (Disease Ontology:DOID:3908); esophagus adenocarcinoma (Disease Ontology:DOID:4914); myelofibrosis (Disease Ontology:DOID:4971); hepatocellular carcinoma (Disease Ontology:DOID:684); acute myeloid leukemia (Disease Ontology:DOID:9119); colorectal cancer (Disease Ontology:DOID:9256); multiple myeloma (Disease Ontology:DOID:9538); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (rno:292673); (R-RNO-5685938); (R-RNO-5696395); (R-RNO-5696400); (R-RNO-6782135); (R-RNO-6783310)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 24, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003684 damaged DNA binding;GO:0003697 single-stranded DNA binding;GO:0001094 TFIID-class transcription factor complex binding;GO:1990841 promoter-specific chromatin binding", "go_cellular_component": "GO:0000110 nucleotide-excision repair factor 1 complex;GO:0070522 ERCC4-ERCC1 complex;GO:0005634 nucleus;GO:0000109 nucleotide-excision repair complex;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006312 mitotic recombination;GO:0006302 double-strand break repair;GO:0070914 UV-damage excision repair;GO:0006310 DNA recombination;GO:0032204 regulation of telomere maintenance", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6GI31-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6GB45-1", "uniprot_id": [ { "id": "A0A8I6GB45_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6GB45", "type": "external" } ], "mass": 76578.0, "length": 685, "protein_name": "Mitotic spindle positioning", "gene_name": "Misp", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Misp; LOC500797", "gene_names_refseq": "", "protein_names_uniprotkb": "Mitotic spindle positioning", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:500797)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, 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"GO:0005884 actin filament;GO:0005886 plasma membrane;GO:0005925 focal adhesion;GO:0030864 cortical actin cytoskeleton;GO:0031616 spindle pole centrosome", "go_biological_process": "GO:0016477 cell migration;GO:0090307 mitotic spindle assembly;GO:0030866 cortical actin cytoskeleton organization;GO:0000132 establishment of mitotic spindle orientation;GO:0030953 astral microtubule organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I6GB45-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AGZ6-1", "uniprot_id": [ { "id": "A0A8I6AGZ6_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AGZ6", "type": "external" } ], "mass": 70622.0, "length": 617, "protein_name": "FAM161 centrosomal protein B", "gene_name": "Fam161b", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Fam161b", "gene_names_refseq": "", 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"protein_name": "Connector enhancer of kinase suppressor of Ras 1", "gene_name": "Cnksr1", "organism": "Rat", "refseq_name": "connector enhancer of kinase suppressor of ras 1 isoform X2", "refseq_ac": [ { "id": "XP_038965563", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038965563", "type": "external" } ], "gene_names_uniprotkb": "Cnksr1", "gene_names_refseq": "Cnksr1", "protein_names_uniprotkb": "Connector enhancer of kinase suppressor of Ras 1", "protein_names_refseq": "connector enhancer of kinase suppressor of ras 1 isoform X2", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0005938 cell cortex", "go_biological_process": "GO:0050808 synapse organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I6AN25-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6G3R2-1", "uniprot_id": [ { "id": "A0A8I6G3R2_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6G3R2", "type": "external" } ], "mass": 100691.0, "length": 914, "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "Cbl", "organism": "Rat", "refseq_name": "E3 ubiquitin-protein ligase CBL", "refseq_ac": [ { "id": "NP_001406884", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001406884", "type": "external" } ], "gene_names_uniprotkb": "Cbl", "gene_names_refseq": "Cbl; RGD1561386; c-Cbl", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase CBL; 2.3.2.27", "protein_names_refseq": "Cas-Br-M (murine) ecotropic retroviral transforming sequence; Casitas B-lineage lymphoma; Cbl proto-oncogene, E3 ubiquitin protein ligase; E3 ubiquitin-protein ligase CBL", "tax_id": 10116, "disease": "juvenile myelomonocytic leukemia (Disease Ontology:DOID:0050458); myeloid neoplasm (Disease Ontology:DOID:0070004); myeloproliferative neoplasm (Disease Ontology:DOID:2226); transient cerebral ischemia (Disease Ontology:DOID:224); osteosarcoma (Disease Ontology:DOID:3347); Noonan syndrome (Disease Ontology:DOID:3490); congenital diaphragmatic hernia (Disease Ontology:DOID:3827); lung non-small cell carcinoma (Disease Ontology:DOID:3908); hyperglycemia (Disease Ontology:DOID:4195); congestive heart failure (Disease Ontology:DOID:6000); hepatocellular carcinoma (Disease Ontology:DOID:684); acute myeloid leukemia (Disease Ontology:DOID:9119); colorectal cancer (Disease Ontology:DOID:9256); multiple myeloma (Disease Ontology:DOID:9538); type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": " (rno:500985); (R-RNO-1059683); (R-RNO-1295596); (R-RNO-1433559); (R-RNO-182971); (R-RNO-2173789); (R-RNO-5654726); (R-RNO-5654727); (R-RNO-5654732); (R-RNO-5654733); (R-RNO-6807004); (R-RNO-8849469); (R-RNO-8856825); (R-RNO-8856828); (R-RNO-912631)", "pathway_count": 15, "publication_count": 3, "publication_id_list": "22673903;30021515;37199660", "class_list": "", "function": "E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; FTO represses NLRP3-mediated pyroptosis and alleviates myocardial ischemia-reperfusion injury via inhibiting CBL-mediated ubiquitination and degradation of beta-catenin., [RefSeq, PubMed]; Results suggest that ubiquitin and the E3 ubiquitin ligases c-Cbl and Cbl-b function as neuroimmune modulators in the subacute phase of neuropathic pain after nerve injury. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 15, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.1.3.86", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.86", "type": "external" }, { "id": "3.1.3.56", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.56", "type": "external" }, { "id": "3.1.3.36", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.36", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "2.7.11.30", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.30", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "3.2.1.31", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.31", "type": "external" } ], "go_molecular_function": "GO:0001784 phosphotyrosine residue binding;GO:0008270 zinc ion binding;GO:0005509 calcium ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0017124 SH3 domain binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0005929 cilium;GO:0005925 focal adhesion", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0016567 protein ubiquitination;GO:0023051 regulation of signaling;GO:1902531 regulation of intracellular signal transduction;GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A8I6G3R2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AS15-1", "uniprot_id": [ { "id": "A0A8I6AS15_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AS15", "type": "external" } ], "mass": 64181.0, "length": 586, "protein_name": "IKAROS family zinc finger 4", "gene_name": "Ikzf4", "organism": "Rat", "refseq_name": "zinc finger protein Eos", "refseq_ac": [ { "id": "NP_001414216", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414216", "type": "external" } ], "gene_names_uniprotkb": "Ikzf4", "gene_names_refseq": "Ikzf4", "protein_names_uniprotkb": "IKAROS family zinc finger 4", "protein_names_refseq": "zinc finger protein Eos; zinc finger protein, subfamily 1A, 4", "tax_id": 10116, "disease": "encephalomyelitis (Disease Ontology:DOID:640)", "pathway": " (rno:100361923)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0003700 DNA-binding transcription factor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0016604 nuclear body;GO:0032991 protein-containing complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0051260 protein homooligomerization;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6AS15-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6GLR7-1", "uniprot_id": [ { "id": "A0A8I6GLR7_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6GLR7", "type": "external" } ], "mass": 465510.0, "length": 4069, "protein_name": "Dynein axonemal heavy chain 3", "gene_name": "Dnah3", "organism": "Rat", "refseq_name": "dynein axonemal heavy chain 3", "refseq_ac": [ { "id": "NP_001414569", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414569", "type": "external" } ], "gene_names_uniprotkb": "Dnah3", "gene_names_refseq": "AABR07005597.1; Dnah3; Dnahc3l; Dnahc3", "protein_names_uniprotkb": "Dynein axonemal heavy chain 3; Axonemal beta dynein heavy chain 3; Ciliary dynein heavy chain 3", "protein_names_refseq": "dynein axonemal heavy chain 3; dynein heavy chain 3, axonemal-like; dynein, axonemal, heavy polypeptide 3", "tax_id": 10116, "disease": "", "pathway": " (rno:117249)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051959 dynein light intermediate chain binding;GO:0045505 dynein intermediate chain binding;GO:0005524 ATP binding;GO:0008569 minus-end-directed microtubule motor activity", "go_cellular_component": "GO:0030286 dynein complex;GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0036126 sperm flagellum;GO:0005858 axonemal dynein complex", "go_biological_process": "GO:0007018 microtubule-based movement;GO:0007288 sperm axoneme assembly;GO:0036159 inner dynein arm assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6GLR7-1", "record_type": "protein", "filter_code": "0000000.0000001.001000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZTL5-1", "uniprot_id": [ { "id": "A0A8I5ZTL5_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZTL5", "type": "external" } ], "mass": 31891.0, "length": 295, "protein_name": "TGFB-induced factor homeobox 1", "gene_name": "Tgif1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Tgif1", "gene_names_refseq": "", "protein_names_uniprotkb": "TGFB-induced factor homeobox 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "holoprosencephaly 4 (Disease Ontology:DOID:0110880); otitis media (Disease Ontology:DOID:10754); holoprosencephaly (Disease Ontology:DOID:4621); muscular atrophy (Disease Ontology:DOID:767)", "pathway": " (R-RNO-2173795)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0070410 co-SMAD binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0010470 regulation of gastrulation;GO:1902871 positive regulation of amacrine cell differentiation;GO:0006351 DNA-templated transcription;GO:0038092 nodal signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I5ZTL5-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6ARV9-1", "uniprot_id": [ { "id": "A0A8I6ARV9_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6ARV9", "type": "external" } ], "mass": 55690.0, "length": 493, "protein_name": "Carboxypeptidase", "gene_name": "Ctsa", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ctsa", "gene_names_refseq": "", "protein_names_uniprotkb": "Carboxypeptidase; 3.4.16.-", "protein_names_refseq": "", "tax_id": 10116, "disease": "brain small vessel disease 6 with leukoencephalopathy (Disease Ontology:DOID:0061236); galactosialidosis (Disease Ontology:DOID:0080540); lysosomal storage disease (Disease Ontology:DOID:3211)", "pathway": " (rno:296370); (R-RNO-2132295); (R-RNO-4085001); (R-RNO-6798695); (R-RNO-9840310)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, 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Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. 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Required for localization of DDX21 and NCL to the granular compartment of the nucleolus. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005730 nucleolus;GO:0032040 small-subunit processome", "go_biological_process": "GO:0042274 ribosomal small subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8J8XQ12-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8L2QHS0-1", "uniprot_id": [ { "id": "A0A8L2QHS0_RAT", "url": "https://www.uniprot.org/uniprot/A0A8L2QHS0", "type": "external" } ], "mass": 103395.0, "length": 960, "protein_name": "Ras-interacting protein 1", "gene_name": "Rasip1", "organism": "Rat", "refseq_name": "ras-interacting protein 1", "refseq_ac": [ { "id": "NP_001099731", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099731", "type": "external" } ], "gene_names_uniprotkb": "Rasip1", "gene_names_refseq": "Rasip1", "protein_names_uniprotkb": "Ras-interacting protein 1", "protein_names_refseq": "ras-interacting protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:292912)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells. May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. 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"go_cellular_component": "GO:0005576 extracellular region;GO:0031012 extracellular matrix;GO:0005588 collagen type V trimer", "go_biological_process": "GO:0007160 cell-matrix adhesion;GO:0030199 collagen fibril organization;GO:0048705 skeletal system morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F7EVZ0-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F7EYK8-1", "uniprot_id": [ { "id": "F7EYK8_RAT", "url": "https://www.uniprot.org/uniprot/F7EYK8", "type": "external" } ], "mass": 72990.0, "length": 678, "protein_name": "Ubiquilin-3", "gene_name": "Ubqln3", "organism": "Rat", "refseq_name": "ubiquilin-3 isoform X1", "refseq_ac": [ { "id": "XP_017444687", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017444687", "type": "external" } ], "gene_names_uniprotkb": "Ubqln3", "gene_names_refseq": "Ubqln3", "protein_names_uniprotkb": 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"length": 210, "protein_name": "Calmodulin-like protein 4", "gene_name": "Calml4", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Calml4", "gene_names_refseq": "", "protein_names_uniprotkb": "Calmodulin-like protein 4", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "As part of the intermicrovillar adhesion complex/IMAC plays a role in epithelial brush border differentiation, controlling microvilli organization and length. Acts as a light chain for MYO7B and is required for efficient targeting of the IMAC to the tips of border brush microvilli., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0030234 enzyme regulator activity;GO:0032028 myosin head/neck binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005902 microvillus", "go_biological_process": "GO:0000226 microtubule cytoskeleton organization;GO:1904970 brush border assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F7F9Q8-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F7FLA1-1", "uniprot_id": [ { "id": "F7FLA1_RAT", "url": "https://www.uniprot.org/uniprot/F7FLA1", "type": "external" } ], "mass": 47385.0, "length": 432, "protein_name": "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "gene_name": "Slc35b2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Slc35b2", "gene_names_refseq": "", "protein_names_uniprotkb": "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "hypomyelinating leukodystrophy 26 (Disease Ontology:DOID:0070403)", "pathway": " (R-RNO-174362); 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Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0042802 identical protein binding;GO:0003714 transcription corepressor activity;GO:0000976 transcription cis-regulatory region binding", "go_cellular_component": "GO:0005634 nucleus;GO:0017053 transcription repressor complex;GO:0005667 transcription regulator complex;GO:0000118 histone deacetylase complex;GO:0072686 mitotic spindle", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006508 proteolysis;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JY80-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5YCM0-1", "uniprot_id": [ { "id": "A0A8I5YCM0_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5YCM0", "type": "external" } ], "mass": 36007.0, "length": 323, "protein_name": "Olfactory receptor", "gene_name": "Or5p58", "organism": "Rat", "refseq_name": "similar to olfactory receptor MOR204-14", "refseq_ac": [ { "id": "NP_001389380", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001389380", "type": "external" } ], "gene_names_uniprotkb": "Or5p58", "gene_names_refseq": "Or5p58; RGD1562400", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 482; similar to olfactory receptor MOR204-14", "tax_id": 10116, "disease": "", "pathway": " (rno:499237)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I5YCM0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZMG7-1", "uniprot_id": [ { "id": "A0A8I5ZMG7_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZMG7", "type": "external" } ], "mass": 66270.0, "length": 568, "protein_name": "Zinc finger protein 950 like 16", "gene_name": "Zfp950l16", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Zfp950l16; LOC102549410", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger protein 950 like 16", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-212436)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I5ZMG7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZMP3-1", "uniprot_id": [ { "id": "A0A8I5ZMP3_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZMP3", "type": "external" } ], "mass": 49080.0, "length": 437, "protein_name": "RT1 class Ia, locus A1", "gene_name": "ENSRNOG00000069209", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ENSRNOG00000069209; RT1-A1", "gene_names_refseq": "", "protein_names_uniprotkb": "RT1 class Ia, locus A1", "protein_names_refseq": "", "tax_id": 10116, "disease": "Stevens-Johnson syndrome (Disease Ontology:DOID:0050426); colitis (Disease Ontology:DOID:0060180); Cytomegalovirus retinitis (Disease Ontology:DOID:0080160); COVID-19 (Disease Ontology:DOID:0080600); ankylosing spondylitis 1 (Disease Ontology:DOID:0080603); erythema nodosum (Disease Ontology:DOID:0080750); occupational asthma (Disease Ontology:DOID:0080820); graft-versus-host disease (Disease Ontology:DOID:0081267); birdshot chorioretinopathy (Disease Ontology:DOID:0111079); psoriasis 1 (Disease Ontology:DOID:0111286); sensorineural hearing loss (Disease Ontology:DOID:10003); spondyloarthropathy (Disease Ontology:DOID:1123); trachoma (Disease Ontology:DOID:11265); sarcoidosis (Disease Ontology:DOID:11335); retinal vasculitis (Disease Ontology:DOID:11563); otosclerosis (Disease Ontology:DOID:12185); Graves' disease (Disease Ontology:DOID:12361); respiratory syncytial virus infectious disease (Disease Ontology:DOID:1273); retinopathy of prematurity (Disease Ontology:DOID:13025); uveitis (Disease Ontology:DOID:13141); Behcet's disease (Disease Ontology:DOID:13241); anterior uveitis (Disease Ontology:DOID:1407); cystic fibrosis (Disease Ontology:DOID:1485); hepatitis C (Disease Ontology:DOID:1883); Takayasu's arteritis (Disease Ontology:DOID:2508); synovitis (Disease Ontology:DOID:2703); dermatitis (Disease Ontology:DOID:2723); asthma (Disease Ontology:DOID:2841); severe acute respiratory syndrome (Disease Ontology:DOID:2945); cerebral infarction (Disease Ontology:DOID:3526); acute retinal necrosis syndrome (Disease Ontology:DOID:3611); thrombophlebitis (Disease Ontology:DOID:3875); tuberculosis (Disease Ontology:DOID:399); cervical cancer (Disease Ontology:DOID:4362); allergic rhinitis (Disease Ontology:DOID:4481); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); uveal melanoma (Disease Ontology:DOID:6039); reactive arthritis (Disease Ontology:DOID:6196); ankylosing spondylitis (Disease Ontology:DOID:7147); diabetic retinopathy (Disease Ontology:DOID:8947); allergic asthma (Disease Ontology:DOID:9415); Meniere's disease (Disease Ontology:DOID:9849); alopecia (Disease Ontology:DOID:987); mitral valve prolapse (Disease Ontology:DOID:988)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in the presentation of foreign antigens to the immune system., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 44, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030881 beta-2-microglobulin binding;GO:0044877 protein-containing complex binding;GO:0042277 peptide binding", "go_cellular_component": "GO:0030670 phagocytic vesicle membrane;GO:0042612 MHC class I protein complex;GO:0098553 lumenal side of endoplasmic reticulum membrane", "go_biological_process": "GO:0002474 antigen processing and presentation of peptide antigen via MHC class I;GO:0001916 positive regulation of T cell mediated cytotoxicity;GO:0045953 negative regulation of natural killer cell mediated cytotoxicity;GO:0002517 T cell tolerance induction;GO:0002657 positive regulation of tolerance induction to nonself antigen", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I5ZMP3-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZN27-1", "uniprot_id": [ { "id": "CNGB1_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZN27", "type": "external" } ], "mass": 147160.0, "length": 1307, "protein_name": "Cyclic nucleotide-gated channel beta-1", "gene_name": "Cngb1", "organism": "Rat", "refseq_name": "cyclic nucleotide-gated channel beta-1 isoform 2", "refseq_ac": [ { "id": "NP_001376189", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376189", "type": "external" } ], "gene_names_uniprotkb": "Cngb1; CNCG2; CNCG3L; CNCG4; RCNC2", "gene_names_refseq": "CNG-4; CNG4; Cngb1; Gm1959", "protein_names_uniprotkb": "Cyclic nucleotide-gated channel beta-1; CNG channel 4; CNG-4; CNG4; Cyclic nucleotide-gated cation channel 4", "protein_names_refseq": "CNG channel 4; cyclic nucleotide gated channel beta 1; cyclic nucleotide-gated cation channel 4; cyclic nucleotide-gated cation channel beta-1; cyclic nucleotide-gated channel beta subunit 1; cyclic nucleotide-gated channel beta-1 isoform 2", "tax_id": 10116, "disease": "retinitis pigmentosa 45 (Disease Ontology:DOID:0110402); retinitis pigmentosa (Disease Ontology:DOID:10584)", "pathway": " (rno:83686); (R-RNO-2485179); (R-RNO-2514859); (R-RNO-5620916)", "pathway_count": 4, "publication_count": 6, "publication_id_list": "10377344;11764791;15134638;27405959;9539801;9878057", "class_list": "", "function": "CNGB1b subunit participates in ligand-gated activation of olfactory CNG channels and, particularly, contributes to rapid termination of odorant signal in an olfactory sensory neuron. Erratum:[Sci Rep. 2018 Jun 28;8:47000. doi: 10.1038/srep47000. PMID: 29952375] Publication Status: Online-Only, [RefSeq, PubMed]; Pore-forming subunit of the olfactory cyclic nucleotide-gated channel. Operates in the cilia of olfactory sensory neurons where chemical stimulation of the odorant is converted to an electrical signal. Mediates odorant-induced cAMP-dependent Ca(2+) influx triggering neuron depolarization. The rise of intracellular Ca(2+) levels potentiates the olfactory response by activating Ca(2+)-dependent Cl(-) channels, but it also serves as a negative feedback signal to desensitize the channel for rapid adaptation to odorants., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]; Pore-forming subunit of the rod cyclic nucleotide-gated channel. Mediates rod photoresponses at dim light converting transient changes in intracellular cGMP levels into electrical signals. In the dark, cGMP levels are high and keep the channel open enabling a steady inward current carried by Na(+) and Ca(2+) ions that leads to membrane depolarization and neurotransmitter release from synaptic terminals. Upon photon absorption cGMP levels decline leading to channel closure and membrane hyperpolarization that ultimately slows neurotransmitter release and signals the presence of light, the end point of the phototransduction cascade. Conducts cGMP- and cAMP-gated ion currents, with permeability for monovalent and divalent cations. The selectivity for Ca(2+) over Na(+) increases with cGMP concentrations, whereas the selectivity among monovalent ions is independent of the cGMP levels., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A0G2JXF2;A0A0G2K685;F1LQB8;O55157", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "1.8.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.-.-", "type": "external" } ], "go_molecular_function": "GO:0005262 calcium channel activity;GO:0044877 protein-containing complex binding;GO:0005223 intracellularly cGMP-activated cation channel activity;GO:0005272 sodium channel activity;GO:0005222 intracellularly cAMP-activated cation channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0043195 terminal bouton;GO:0001750 photoreceptor outer segment;GO:0017071 intracellular cyclic nucleotide activated cation channel complex", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0010628 positive regulation of gene expression;GO:0006816 calcium ion transport;GO:0051480 regulation of cytosolic calcium ion concentration;GO:0051899 membrane depolarization", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A8I5ZN27-1", "record_type": "protein", "filter_code": "0000000.0100111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZNW0-1", "uniprot_id": [ { "id": "A0A8I5ZNW0_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZNW0", "type": "external" } ], "mass": 13514.0, "length": 124, "protein_name": "Immunoglobulin V-set domain-containing protein", "gene_name": "ENSRNOG00000066577", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ENSRNOG00000066577", "gene_names_refseq": "", "protein_names_uniprotkb": "Immunoglobulin V-set domain-containing protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0019814 immunoglobulin complex", "go_biological_process": "GO:0006955 immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I5ZNW0-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZRJ5-1", "uniprot_id": [ { "id": "A0A8I5ZRJ5_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZRJ5", "type": "external" } ], "mass": 25311.0, "length": 225, "protein_name": "Rho GDP-dissociation inhibitor 3", "gene_name": "Arhgdig", "organism": "Rat", "refseq_name": "rho GDP-dissociation inhibitor 3", "refseq_ac": [ { "id": "NP_001101739", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101739", "type": "external" } ], "gene_names_uniprotkb": "Arhgdig", "gene_names_refseq": "Arhgdig", "protein_names_uniprotkb": "Rho GDP-dissociation inhibitor 3; Rho-GDI gamma", "protein_names_refseq": "Rho GDP dissociation inhibitor (GDI) gamma; rho GDP-dissociation inhibitor 3", "tax_id": 10116, "disease": "", "pathway": " (rno:360500); (R-RNO-9013026); (R-RNO-9013148); (R-RNO-9013407); (R-RNO-9013408)", "pathway_count": 5, "publication_count": 2, "publication_id_list": "20051515;38029612", "class_list": "", "function": "Corticosterone, via SGK phosphorylation of GDI at Ser-213, increases the formation of GDI-Rab4 complex, facilitating the functional cycle of Rab4 and Rab4-mediated recycling of AMPARs to the synaptic membrane, [RefSeq, PubMed]; Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP., [UniProtKB, UniProtKB]; RhoGDI3 at the trans-Golgi network participates in NLRP3 inflammasome activation, VSMC phenotypic modulation, and neointima formation., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005094 Rho GDP-dissociation inhibitor activity;GO:0005096 GTPase activator activity;GO:0030695 GTPase regulator activity;GO:0005092 GDP-dissociation inhibitor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0007266 Rho protein signal transduction;GO:0032880 regulation of protein localization;GO:0001835 blastocyst hatching", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8I5ZRJ5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZRU6-1", "uniprot_id": [ { "id": "A0A8I5ZRU6_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZRU6", "type": "external" } ], "mass": 48263.0, "length": 421, "protein_name": "Serpin family A member 1F like 2", "gene_name": "ENSRNOG00000064752", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ENSRNOG00000064752; 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In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, 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"https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005516 calmodulin binding;GO:0005525 GTP binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007265 Ras protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6ABM0-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6ACT0-1", "uniprot_id": [ { "id": "A0A8I6ACT0_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6ACT0", "type": "external" } ], "mass": 60853.0, "length": 573, "protein_name": "60 kDa heat shock protein, mitochondrial", "gene_name": "Hspd1l1", "organism": "Rat", "refseq_name": "60 kDa heat shock protein, mitochondrial-like", "refseq_ac": [ { "id": "XP_063133708", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063133708", "type": "external" } ], "gene_names_uniprotkb": "Hspd1l1; LOC103694176", "gene_names_refseq": "Hspd1l1", "protein_names_uniprotkb": "60 kDa heat shock protein, mitochondrial; 5.6.1.7; 60 kDa chaperonin; Chaperonin 60; Heat shock protein 60; Mitochondrial matrix protein P1", "protein_names_refseq": "60 kDa heat shock protein, mitochondrial-like", "tax_id": 10116, "disease": "hypomyelinating leukodystrophy 4 (Disease Ontology:DOID:0060789); hereditary spastic paraplegia 13 (Disease Ontology:DOID:0110766); glucose intolerance (Disease Ontology:DOID:10603); Alzheimer's disease (Disease Ontology:DOID:10652); autistic disorder (Disease Ontology:DOID:12849); Down syndrome (Disease Ontology:DOID:14250); cystic fibrosis (Disease Ontology:DOID:1485); arteriosclerosis (Disease Ontology:DOID:2349); hereditary spastic paraplegia (Disease Ontology:DOID:2476); coronary artery disease (Disease Ontology:DOID:3393); carotid artery disease (Disease Ontology:DOID:3407); systemic juvenile rheumatoid arthritis (Disease Ontology:DOID:676); rheumatoid arthritis (Disease Ontology:DOID:7148); systemic lupus erythematosus (Disease Ontology:DOID:9074); aphthous stomatitis (Disease Ontology:DOID:9663)", "pathway": " (rno:103694176)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp10, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and association with 2 heptameric rings of the co-chaperonin Hsp10. This leads to sequestration of the substrate protein in the inner cavity of Hsp60 where, for a certain period of time, it can fold undisturbed by other cell components. Synchronous hydrolysis of ATP in all Hsp60 subunits results in the dissociation of the chaperonin rings and the release of ADP and the folded substrate protein., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 15, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0051087 protein-folding chaperone binding;GO:0140662 ATP-dependent protein folding chaperone", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0032727 positive regulation of interferon-alpha production;GO:0045041 protein import into mitochondrial intermembrane space;GO:0032755 positive regulation of interleukin-6 production;GO:0042110 T cell activation;GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6ACT0-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AFA7-1", "uniprot_id": [ { "id": "A0A8I6AFA7_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AFA7", "type": "external" } ], "mass": 34592.0, "length": 309, "protein_name": "Olfactory receptor", "gene_name": "Or2y1c", "organism": "Rat", "refseq_name": "olfactory receptor Olr1394", "refseq_ac": [ { "id": "NP_001001091", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001091", "type": "external" } ], "gene_names_uniprotkb": "Or2y1c; Or2y1", "gene_names_refseq": "Olr1394; Or2y1c", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1394; olfactory receptor Olr1394; olfactory receptor gene Olr1394", "tax_id": 10116, "disease": "", "pathway": " (rno:405985)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6AFA7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AEP5-1", "uniprot_id": [ { "id": "A0A8I6AEP5_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AEP5", "type": "external" } ], "mass": 61734.0, "length": 564, "protein_name": "Polyamine oxidase", "gene_name": "Paox", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Paox", "gene_names_refseq": "", "protein_names_uniprotkb": "Polyamine oxidase", "protein_names_refseq": "", "tax_id": 10116, "disease": "lung non-small cell carcinoma (Disease Ontology:DOID:3908)", "pathway": " (rno:293589)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016491 oxidoreductase activity;GO:0046592 polyamine oxidase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005782 peroxisomal matrix", "go_biological_process": "GO:0046203 spermidine catabolic process;GO:0006598 polyamine catabolic process;GO:0009446 putrescine biosynthetic process;GO:0009447 putrescine catabolic process;GO:0046208 spermine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6AEP5-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F7F4X8-1", "uniprot_id": [ { "id": "F7F4X8_RAT", "url": "https://www.uniprot.org/uniprot/F7F4X8", "type": "external" } ], "mass": 31634.0, "length": 290, "protein_name": "TNF receptor superfamily member 14", "gene_name": "Tnfrsf14", "organism": "Rat", "refseq_name": "tumor necrosis factor receptor superfamily member 14 isoform X4", "refseq_ac": [ { "id": "XP_006239648", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006239648", "type": "external" } ], "gene_names_uniprotkb": "Tnfrsf14", "gene_names_refseq": "Tnfrsf14", "protein_names_uniprotkb": "TNF receptor superfamily member 14", "protein_names_refseq": "tumor necrosis factor receptor superfamily member 14 isoform X4", "tax_id": 10116, "disease": "arteriosclerosis (Disease Ontology:DOID:2349); myocardial infarction (Disease Ontology:DOID:5844)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding;GO:0048018 receptor ligand activity;GO:0019955 cytokine binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009897 external side of plasma membrane;GO:0098797 plasma membrane protein complex;GO:0002947 tumor necrosis factor receptor superfamily complex", "go_biological_process": "GO:0050829 defense response to Gram-negative bacterium;GO:0050830 defense response to Gram-positive bacterium;GO:2000406 positive regulation of T cell migration;GO:0031295 T cell costimulation;GO:0042130 negative regulation of T cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F7F4X8-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZKS5-1", "uniprot_id": [ { "id": "A0A8I5ZKS5_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZKS5", "type": "external" } ], "mass": 86355.0, "length": 767, "protein_name": "Protein transport protein SEC23", "gene_name": "Sec23b", "organism": "Rat", "refseq_name": "protein transport protein Sec23B", "refseq_ac": [ { "id": "NP_001264164", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264164", "type": "external" } ], "gene_names_uniprotkb": "Sec23b", "gene_names_refseq": "Sec23b", "protein_names_uniprotkb": "Protein transport protein SEC23", "protein_names_refseq": "Sec23 homolog B, COPII coat complex component; Sec23 homolog B, coat complex II component; protein transport protein Sec23B", "tax_id": 10116, "disease": "craniolenticulosutural dysplasia (Disease Ontology:DOID:0070307); Cowden syndrome 7 (Disease Ontology:DOID:0081003); congenital dyserythropoietic anemia type II (Disease Ontology:DOID:0111401); Roberts syndrome (Disease Ontology:DOID:5325)", "pathway": " (rno:362226)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29393594;38843836", "class_list": "", "function": "Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005789 endoplasmic reticulum membrane;GO:0030127 COPII vesicle coat;GO:0070971 endoplasmic reticulum exit site;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0090114 COPII-coated vesicle budding;GO:0090110 COPII-coated vesicle cargo loading", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A8I5ZKS5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A1R7-1", "uniprot_id": [ { "id": "A0A8I6A1R7_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A1R7", "type": "external" } ], "mass": 124204.0, "length": 1084, "protein_name": "Zinc finger protein 729b", "gene_name": "Zfp729b", "organism": "Rat", "refseq_name": "zinc finger protein 729b isoform 1", "refseq_ac": [ { "id": "NP_001395704", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001395704", "type": "external" } ], "gene_names_uniprotkb": "Zfp729b", "gene_names_refseq": "Zfp729b; Zfp748l1", "protein_names_uniprotkb": "Zinc finger protein 729b", "protein_names_refseq": "zinc finger protein 728-like; zinc finger protein 729b isoform 1; zinc finger protein 748 like 1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6A1R7-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A3C7-1", "uniprot_id": [ { "id": "A0A8I6A3C7_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A3C7", "type": "external" } ], "mass": 73022.0, "length": 659, "protein_name": "Sorting nexin 9", "gene_name": "Snx9", "organism": "Rat", "refseq_name": "sorting nexin-9 isoform X1", "refseq_ac": [ { "id": "XP_038946688", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038946688", "type": "external" } ], "gene_names_uniprotkb": "Snx9", "gene_names_refseq": "Snx9", "protein_names_uniprotkb": "Sorting nexin 9", "protein_names_refseq": "sorting nexin-9 isoform X1", "tax_id": 10116, "disease": "colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (rno:683687); (R-RNO-432722); (R-RNO-8856828)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Promotes internalization of TNFR. Promotes degradation of EGFR after EGF signaling. Stimulates the GTPase activity of DNM1. Promotes DNM1 oligomerization. Promotes activation of the Arp2/3 complex by WASL, and thereby plays a role in the reorganization of the F-actin cytoskeleton. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Has lower affinity for membranes enriched in phosphatidylinositol 3-phosphate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0031625 ubiquitin protein ligase binding;GO:0005545 1-phosphatidylinositol binding;GO:0071933 Arp2/3 complex binding;GO:0035091 phosphatidylinositol binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005905 clathrin-coated pit;GO:0030659 cytoplasmic vesicle membrane;GO:0030136 clathrin-coated vesicle", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0051044 positive regulation of membrane protein ectodomain proteolysis;GO:0006898 receptor-mediated endocytosis;GO:0016197 endosomal transport;GO:0000281 mitotic cytokinesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6A3C7-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6ALA8-1", "uniprot_id": [ { "id": "A0A8I6ALA8_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6ALA8", "type": "external" } ], "mass": 76383.0, "length": 688, "protein_name": "TBC1 domain family member 25", "gene_name": "Tbc1d25", "organism": "Rat", "refseq_name": "TBC1 domain family member 25", "refseq_ac": [ { "id": "NP_001100425", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100425", "type": "external" } ], "gene_names_uniprotkb": "Tbc1d25", "gene_names_refseq": "Oatl1; RGD1559711; Tbc1d25", "protein_names_uniprotkb": "TBC1 domain family member 25", "protein_names_refseq": "TBC1 domain family member 25; ornithine aminotransferase-like 1", "tax_id": 10116, "disease": "", "pathway": " (rno:302552); (R-RNO-8854214)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "22673903;38100060", "class_list": "", "function": "Acts as a GTPase-activating protein specific for RAB33B. Involved in the regulation of autophagosome maturation, the process in which autophagosomes fuse with endosomes and lysosomes., [UniProtKB, UniProtKB, UniProtKB]; TBC1 domain family member 25 protects against myocardial apoptosis and the proinflammatory response triggered by ischemia-reperfusion injury through suppression of the TAK1-JNK/p38 MAPK signaling cascade., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005776 autophagosome", "go_biological_process": "GO:1901096 regulation of autophagosome maturation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8I6ALA8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5Y0H0-1", "uniprot_id": [ { "id": "A0A8I5Y0H0_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5Y0H0", "type": "external" } ], "mass": 89589.0, "length": 777, "protein_name": "Cullin-1", "gene_name": "Cul1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Cul1", "gene_names_refseq": "", "protein_names_uniprotkb": "Cullin-1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:362356); (R-RNO-1169091); (R-RNO-1170546); (R-RNO-174113); (R-RNO-187577); (R-RNO-195253); (R-RNO-202424); (R-RNO-2565942); (R-RNO-2871837); (R-RNO-5607761); (R-RNO-5607764); (R-RNO-5610780); (R-RNO-5610785); (R-RNO-5676590); (R-RNO-5684264); (R-RNO-68949); (R-RNO-69231); (R-RNO-69601); (R-RNO-8854050); (R-RNO-8951664); (R-RNO-9020702); (R-RNO-917937); (R-RNO-9762114); (R-RNO-983168); (R-RNO-9929356)", "pathway_count": 25, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding;GO:0160072 ubiquitin ligase complex scaffold activity", "go_cellular_component": "GO:0031461 cullin-RING ubiquitin ligase complex;GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0008283 cell population proliferation;GO:0006915 apoptotic process;GO:0043123 positive regulation of canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I5Y0H0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AJN5-1", "uniprot_id": [ { "id": "A0A8I6AJN5_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AJN5", "type": "external" } ], "mass": 24253.0, "length": 215, "protein_name": "Lipid transferase CIDEA", "gene_name": "Cidea", "organism": "Rat", "refseq_name": "lipid transferase CIDEA", "refseq_ac": [ { "id": "NP_001163938", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163938", "type": "external" } ], "gene_names_uniprotkb": "Cidea", "gene_names_refseq": "Cidea", "protein_names_uniprotkb": "Lipid transferase CIDEA; Cell death activator CIDE-A; Cell death-inducing DFFA-like effector A", "protein_names_refseq": "cell death activator CIDE-A; cell death-inducing DNA fragmentation factor, alpha subunit-like effector A; lipid transferase CIDEA", "tax_id": 10116, "disease": "obesity (Disease Ontology:DOID:9970)", "pathway": " (rno:291541); (R-RNO-8964572)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "19577538;33661766", "class_list": "", "function": "Cell death-associated lipid droplet protein CIDE-A is a noncanonical marker of endoplasmic reticulum stress. Publication Status: Online-Only, [RefSeq, PubMed]; These results suggest that acute cold exposure resulted in down-regulation of CIDEA in interscapular brown adipose tissue by sympathetically activated beta(3)-adrenoreceptor-mediated mechanisms in rats., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0070300 phosphatidic acid binding;GO:0120013 lipid transfer activity", "go_cellular_component": "GO:0005811 lipid droplet;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005740 mitochondrial envelope", "go_biological_process": "GO:0006915 apoptotic process;GO:0019915 lipid storage;GO:0070417 cellular response to cold;GO:0001659 temperature homeostasis;GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8I6AJN5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AG34-1", "uniprot_id": [ { "id": "A0A8I6AG34_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AG34", "type": "external" } ], "mass": 137226.0, "length": 1223, "protein_name": "Gse1 coiled-coil protein", "gene_name": "Gse1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Gse1", "gene_names_refseq": "", "protein_names_uniprotkb": "Gse1 coiled-coil protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "stomach cancer (Disease Ontology:DOID:10534)", "pathway": " (rno:307913)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0001701 in utero embryonic development;GO:0001890 placenta development;GO:0010467 gene expression", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6AG34-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AJZ8-1", "uniprot_id": [ { "id": "A0A8I6AJZ8_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AJZ8", "type": "external" } ], "mass": 54158.0, "length": 488, "protein_name": "E3 ubiquitin-protein ligase Hakai", "gene_name": "Cbll1", "organism": "Rat", "refseq_name": "E3 ubiquitin-protein ligase Hakai isoform 3", "refseq_ac": [ { "id": "NP_001101488", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101488", "type": "external" } ], "gene_names_uniprotkb": "Cbll1", "gene_names_refseq": "Cbll1", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase Hakai; 2.3.2.27; Casitas B-lineage lymphoma-transforming sequence-like protein 1; RING-type E3 ubiquitin transferase Hakai", "protein_names_refseq": "Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1; Casitas B-lineage lymphoma-like 1; Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1; Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase; E3 ubiquitin-protein ligase Hakai isoform 3; E3 ubiquitin-protein ligase Hakai", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-9766229); (R-RNO-983168); (R-RNO-9958810)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "E3 ubiquitin-protein ligase that mediates ubiquitination of several tyrosine-phosphorylated Src substrates, including CDH1, CTTN and DOK1. Targets CDH1 for endocytosis and degradation. Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing. Its function in the WMM complex is unknown., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, 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"https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25", "type": "external" }, { "id": "3.4.22.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.1", "type": "external" }, { "id": "3.4.22.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.15", "type": "external" }, { "id": "3.4.22.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.27", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0036396 RNA N6-methyladenosine methyltransferase complex;GO:0005737 cytoplasm;GO:0016607 nuclear speck;GO:0005634 nucleus", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0030155 regulation of cell adhesion;GO:0006397 mRNA processing;GO:0007162 negative regulation of cell adhesion;GO:0030335 positive regulation of cell migration", 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Tgap1l3; Tgap1l8", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Tgap1l11; Tgap1l3; Tgap1l8; LOC103691539; LOC678817; RGD1563562; Tgap1l3; Tgap1l8", "gene_names_refseq": "", "protein_names_uniprotkb": "Rho-GAP domain-containing protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:678817)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "", "go_biological_process": "GO:0007165 signal transduction;GO:0035023 regulation of Rho protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6GKX2-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KAG4-1", "uniprot_id": [ { "id": "A0A0G2KAG4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KAG4", "type": "external" } ], "mass": 21022.0, "length": 187, "protein_name": "FAM3 metabolism regulating signaling molecule B", "gene_name": "Fam3b", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Fam3b", "gene_names_refseq": "", "protein_names_uniprotkb": "FAM3 metabolism regulating signaling molecule B", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:304050)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030246 carbohydrate binding;GO:0005125 cytokine activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space", "go_biological_process": "GO:0007165 signal transduction;GO:0030073 insulin secretion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2KAG4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZPC4-1", "uniprot_id": [ { "id": "A0A8I5ZPC4_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZPC4", "type": "external" } ], "mass": 39256.0, "length": 355, "protein_name": "Solute carrier family 35 member D1", "gene_name": "Slc35d1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Slc35d1", "gene_names_refseq": "", "protein_names_uniprotkb": "Solute carrier family 35 member D1", "protein_names_refseq": "", "tax_id": 10116, "disease": "schneckenbecken dysplasia (Disease Ontology:DOID:0050775); depressive disorder (Disease Ontology:DOID:1596)", "pathway": " (R-RNO-173599); (R-RNO-727802)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015297 antiporter activity;GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity;GO:0005461 UDP-glucuronate transmembrane transporter activity;GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity;GO:0005463 UDP-N-acetylgalactosamine transmembrane transporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0050650 chondroitin sulfate proteoglycan biosynthetic process;GO:0090481 pyrimidine nucleotide-sugar transmembrane transport;GO:0048706 embryonic skeletal system development;GO:0015780 nucleotide-sugar transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I5ZPC4-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZVG2-1", "uniprot_id": [ { "id": "A0A8I5ZVG2_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZVG2", "type": "external" } ], "mass": 104893.0, "length": 938, "protein_name": "Catenin delta 1", "gene_name": "Ctnnd1", "organism": "Rat", "refseq_name": "catenin delta-1 isoform b", "refseq_ac": [ { "id": "NP_001420299", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001420299", "type": "external" } ], "gene_names_uniprotkb": "Ctnnd1", "gene_names_refseq": "Catns; Ctnnd1; P120", "protein_names_uniprotkb": "Catenin delta 1", "protein_names_refseq": "catenin (cadherin associated protein), delta 1; catenin delta-1 isoform b; catenin src; p120 catenin", "tax_id": 10116, "disease": "oral squamous cell carcinoma (Disease Ontology:DOID:0050866); autism spectrum disorder (Disease Ontology:DOID:0060041); blepharocheilodontic syndrome 2 (Disease Ontology:DOID:0080346); pulmonary hypertension (Disease Ontology:DOID:6432)", "pathway": " (rno:311163); (R-RNO-418990); (R-RNO-5218920); (R-RNO-9762292); (R-RNO-9764561); (R-RNO-9766229); (R-RNO-9958810); (R-RNO-9958825)", "pathway_count": 8, "publication_count": 4, "publication_id_list": "16396499;16641100;22673903;30995547", "class_list": "", "function": "Decreased expression of p120-catenin was detected in intracranial aneurysm endothelium., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0045296 cadherin binding;GO:0005102 signaling receptor binding;GO:0019901 protein kinase binding;GO:0019904 protein domain specific binding;GO:0050839 cell adhesion molecule binding", "go_cellular_component": "GO:0070161 anchoring junction;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005912 adherens junction", "go_biological_process": "GO:0098609 cell-cell adhesion;GO:0010829 negative regulation of D-glucose transmembrane transport;GO:1902532 negative regulation of intracellular signal transduction;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0007155 cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A8I5ZVG2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A1C4-1", "uniprot_id": [ { "id": "A0A8I6A1C4_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A1C4", "type": "external" } ], "mass": 207152.0, "length": 1814, "protein_name": "E3 ubiquitin-protein ligase SHPRH", "gene_name": "Shprh", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Shprh", "gene_names_refseq": "", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase SHPRH; 2.3.2.27; RING-type E3 ubiquitin transferase SHPRH; SNF2, histone-linker, PHD and RING finger domain-containing helicase", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:308282); (R-RNO-8866654)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "E3 ubiquitin-protein ligase involved in DNA repair. Upon genotoxic stress, accepts ubiquitin from the UBE2N-UBE2V2 E2 complex and transfers it to 'Lys-164' of PCNA which had been monoubiquitinated by UBE2A/B-RAD18, promoting the formation of non-canonical poly-ubiquitin chains linked through 'Lys-63'., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0016787 hydrolase activity;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000786 nucleosome", "go_biological_process": "GO:0006281 DNA repair;GO:0006974 DNA damage response;GO:0006334 nucleosome assembly;GO:0000209 protein polyubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6A1C4-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6ABG6-1", "uniprot_id": [ { "id": "A0A8I6ABG6_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6ABG6", "type": "external" } ], "mass": 271338.0, "length": 2558, "protein_name": "Talin 1", "gene_name": "Tln1", "organism": "Rat", "refseq_name": "talin-1 isoform X1", "refseq_ac": [ { "id": "XP_063143800", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063143800", "type": "external" } ], "gene_names_uniprotkb": "Tln1", "gene_names_refseq": "Tln1; Tln", "protein_names_uniprotkb": "Talin 1", "protein_names_refseq": "talin-1 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:313494); (R-RNO-114608); (R-RNO-354192); (R-RNO-354194); (R-RNO-372708); (R-RNO-399955); (R-RNO-445355); (R-RNO-5674135)", "pathway_count": 8, "publication_count": 2, "publication_id_list": "16641100;22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0005200 structural constituent of cytoskeleton;GO:0051015 actin filament binding;GO:0017166 vinculin binding;GO:0030274 LIM domain binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005912 adherens junction;GO:0005925 focal adhesion", "go_biological_process": "GO:0007044 cell-substrate junction assembly;GO:0007229 integrin-mediated signaling pathway;GO:0030036 actin cytoskeleton organization;GO:0098609 cell-cell adhesion;GO:0030866 cortical actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8I6ABG6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O70631-1", "uniprot_id": [ { "id": "EST2C_RAT", "url": "https://www.uniprot.org/uniprot/O70631", "type": "external" } ], "mass": 62170.0, "length": 561, "protein_name": "Acylcarnitine hydrolase", "gene_name": "Ces2c; Ces2", "organism": "Rat", "refseq_name": "acylcarnitine hydrolase precursor", "refseq_ac": [ { "id": "NP_598270", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_598270", "type": "external" } ], "gene_names_uniprotkb": "Ces2c; Ces2; Ces2c; Ces2l; Ces2; LOC100910040", "gene_names_refseq": "ACH M1; CESRL4; Ces2c; Ces2l; Ces2", "protein_names_uniprotkb": "Acylcarnitine hydrolase; 3.1.1.-; 3.1.1.28; ACH M1; Carboxylic ester hydrolase", "protein_names_refseq": "acylcarnitine hydrolase precursor; acylcarnitine hydrolase-like; carboxylesterase 2 (intestine, liver); carboxylic ester hydrolase", "tax_id": 10116, "disease": "", "pathway": " (rno:100910144); (rno:171118)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "12230550;15794950;17392394;17764701;29393594", "class_list": "", "function": "CES2 isoenzymes shown to be major intestinal esterases in first pass hydrolysis of ester containing drugs., [RefSeq, PubMed]; Comparative analysis of CES1 and CES2 in liver and small intestine of humans, monkeys, dogs, rabbits and rats, [RefSeq, PubMed]; Hydrolase with high activity towards palmitoylcarnitine. Is also active with p-nitrophenylacetate and alpha-naphthylacetate (By similarity). May also hydrolyze retinyl esters (PubMed:12230550)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "G3V9D8", "ec_number_list": [ { "id": "3.1.1.88", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.88", "type": "external" }, { "id": "3.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.-", "type": "external" }, { "id": "3.1.1.28", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.28", "type": "external" }, { "id": "3.1.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.23", "type": "external" }, { "id": "3.1.1.79", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.79", "type": "external" }, { "id": "3.1.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.1", "type": "external" }, { "id": "3.1.1.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.67", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" } ], "go_molecular_function": "GO:0047619 acylcarnitine hydrolase activity;GO:0050253 retinyl-palmitate esterase activity;GO:0047376 all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity;GO:0106435 carboxylesterase activity;GO:0052689 carboxylic ester hydrolase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0043231 intracellular membrane-bounded organelle", "go_biological_process": "GO:0001523 retinoid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "O70631-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5XWR9-1", "uniprot_id": [ { "id": "A0A8I5XWR9_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5XWR9", "type": "external" } ], "mass": 101055.0, "length": 903, "protein_name": "Zinc finger CCCH type containing 12C", "gene_name": "Zc3h12c", "organism": "Rat", "refseq_name": "probable ribonuclease ZC3H12C isoform X1", "refseq_ac": [ { "id": "XP_006243135", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006243135", "type": "external" } ], "gene_names_uniprotkb": "Zc3h12c", "gene_names_refseq": "RGD1565078; Zc3h12c", "protein_names_uniprotkb": "Zinc finger CCCH type containing 12C", "protein_names_refseq": "probable ribonuclease ZC3H12C isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:315658)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16641100", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0016787 hydrolase activity;GO:0004519 endonuclease activity;GO:0003729 mRNA binding;GO:0004521 RNA endonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0036464 cytoplasmic ribonucleoprotein granule", "go_biological_process": "GO:0061158 3'-UTR-mediated mRNA destabilization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I5XWR9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q4KLN3-1", "uniprot_id": [ { "id": "Q4KLN3_RAT", "url": "https://www.uniprot.org/uniprot/Q4KLN3", "type": "external" } ], "mass": 73856.0, "length": 655, "protein_name": "SRSF protein kinase 1", "gene_name": "Srpk1", "organism": "Rat", "refseq_name": "SRSF protein kinase 1", "refseq_ac": [ { "id": "NP_001020897", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020897", "type": "external" } ], "gene_names_uniprotkb": "Srpk1", "gene_names_refseq": "Srpk1", "protein_names_uniprotkb": "SRSF protein kinase 1; 2.7.11.1; SFRS protein kinase 1; Serine/arginine-rich protein-specific kinase 1", "protein_names_refseq": "SFRS protein kinase 1; SRSF protein kinase 1; serine/arginine-rich protein specific kinase 1; serine/threonine-protein kinase SRPK1", "tax_id": 10116, "disease": "", "pathway": " (rno:361811)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "22673903;29393594;30101479;33167866", "class_list": "", "function": "Downregulation of long noncoding RNA DLEU1 attenuates hypersensitivity in chronic constriction injury-induced neuropathic pain in rats by targeting miR-133a-3p/SRPK1 axis. Publication Status: Online-Only, [RefSeq, PubMed]; The vascular walls in Intracranial aneurysm rat models produced high levels of SRPK1 expression and an activated PI3 K/Akt signaling pathway, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "E9PTN4", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.34", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" }, { "id": "2.7.11.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.19", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.11.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.4", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.4.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.18", "type": "external" }, { "id": "3.1.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.24.-", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0000287 magnesium ion binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016604 nuclear body;GO:0016363 nuclear matrix;GO:0005694 chromosome;GO:0005634 nucleus", "go_biological_process": "GO:0006397 mRNA processing;GO:0007059 chromosome segregation;GO:0030154 cell differentiation;GO:0008380 RNA splicing;GO:0006468 protein phosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q4KLN3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZK79-1", "uniprot_id": [ { "id": "A0A8I5ZK79_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZK79", "type": "external" } ], "mass": 24982.0, "length": 219, "protein_name": "Phosphatidylinositol glycan anchor biosynthesis, class F", "gene_name": "Pigf", "organism": "Rat", "refseq_name": "phosphatidylinositol-glycan biosynthesis class F protein", "refseq_ac": [ { "id": "NP_001385898", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385898", "type": "external" } ], "gene_names_uniprotkb": "Pigf", "gene_names_refseq": "Pigf", "protein_names_uniprotkb": "Phosphatidylinositol glycan anchor biosynthesis, class F", "protein_names_refseq": "phosphatidylinositol-glycan biosynthesis class F protein", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-162710)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "27280428", "class_list": "", "function": "Thus, a tilt in the angiogenic balance toward anti-angiogenic sFlt-1 is associated with decreased vascular relaxation and increased vasoconstriction and BP. Restoring the angiogenic/antiangiogenic balance using PlGF enhances endothelial NO-cGMP vascular relaxation and decreases vasoconstriction and BP in HTN-Preg rats and could offer a new approach in the management of PE., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051377 mannose-ethanolamine phosphotransferase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006506 GPI anchor biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I5ZK79-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZNG4-1", "uniprot_id": [ { "id": "A0A8I5ZNG4_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZNG4", "type": "external" } ], "mass": 194656.0, "length": 1733, "protein_name": "RPTOR independent companion of MTOR, complex 2", "gene_name": "Rictor", "organism": "Rat", "refseq_name": "rapamycin-insensitive companion of mTOR isoform X1", "refseq_ac": [ { "id": "XP_038959455", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038959455", "type": "external" } ], "gene_names_uniprotkb": "Rictor", "gene_names_refseq": "Rictor", "protein_names_uniprotkb": "RPTOR independent companion of MTOR, complex 2", "protein_names_refseq": "rapamycin-insensitive companion of mTOR isoform X1", "tax_id": 10116, "disease": "colorectal adenocarcinoma (Disease Ontology:DOID:0050861); 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"A0A8I5ZZ56_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZZ56", "type": "external" } ], "mass": 105666.0, "length": 923, "protein_name": "Inner centromere protein", "gene_name": "Incenp", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Incenp", "gene_names_refseq": "", "protein_names_uniprotkb": "Inner centromere protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-141430); (R-RNO-141444); (R-RNO-2467813); (R-RNO-2500257); (R-RNO-4615885); (R-RNO-5663220); (R-RNO-68877); (R-RNO-9648025)", "pathway_count": 8, "publication_count": 2, "publication_id_list": "16641100;22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0140677 molecular function activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005819 spindle;GO:0005874 microtubule;GO:0000776 kinetochore;GO:0030496 midbody", "go_biological_process": "GO:0007059 chromosome segregation;GO:0051301 cell division;GO:0051310 metaphase chromosome alignment;GO:0000281 mitotic cytokinesis;GO:0051257 meiotic spindle midzone assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8I5ZZ56-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZQ14-1", "uniprot_id": [ { "id": "A0A8I5ZQ14_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZQ14", "type": "external" } ], "mass": 84279.0, "length": 763, "protein_name": "AFG3 (ATPase family gene 3)-like 1", "gene_name": "Afg3l1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Afg3l1", "gene_names_refseq": "", "protein_names_uniprotkb": "AFG3 (ATPase family gene 3)-like 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "spinocerebellar ataxia 28 (Disease Ontology:DOID:0050977); optic atrophy 12 (Disease Ontology:DOID:0080840); neurodegenerative disease (Disease Ontology:DOID:1289); hereditary spastic paraplegia (Disease Ontology:DOID:2476)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "7.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.9.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.9.1.1", "type": "external" }, { "id": "6.1.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.12", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" } ], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0016887 ATP hydrolysis activity;GO:0004176 ATP-dependent peptidase activity", "go_cellular_component": "GO:0005745 m-AAA complex;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0008053 mitochondrial fusion;GO:0034982 mitochondrial protein processing;GO:0042407 cristae formation;GO:0006508 proteolysis;GO:0051604 protein maturation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I5ZQ14-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5XVM7-1", "uniprot_id": [ { "id": "A0A8I5XVM7_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5XVM7", "type": "external" } ], "mass": 17486.0, "length": 158, "protein_name": "OCIA domain containing 2", "gene_name": "Ociad2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ociad2", "gene_names_refseq": "", "protein_names_uniprotkb": "OCIA domain containing 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005768 endosome", "go_biological_process": "GO:0016477 cell migration;GO:0009617 response to bacterium;GO:0034551 mitochondrial respiratory chain complex III assembly;GO:2000736 regulation of stem cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I5XVM7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZKA9-1", "uniprot_id": [ { "id": "A0A8I5ZKA9_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZKA9", "type": "external" } ], "mass": 71394.0, "length": 632, "protein_name": "ATP binding cassette subfamily D member 4", "gene_name": "Abcd4", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Abcd4", "gene_names_refseq": "", "protein_names_uniprotkb": "ATP binding cassette subfamily D member 4", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:299196)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Lysosomal membrane protein that transports cobalamin (Vitamin B12) from the lysosomal lumen to the cytosol in an ATP-dependent manner. Targeted by LMBRD1 lysosomal chaperone from the endoplasmic reticulum to the lysosomal membrane. Then forms a complex with lysosomal chaperone LMBRD1 and cytosolic MMACHC to transport cobalamin across the lysosomal membrane., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "7.6.2.8", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.8", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0140359 ABC-type transporter activity;GO:0042802 identical protein binding;GO:0015420 ABC-type vitamin B12 transporter activity", "go_cellular_component": "GO:0031090 organelle membrane;GO:0005777 peroxisome;GO:0005765 lysosomal membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:1990830 cellular response to leukemia inhibitory factor;GO:0009235 cobalamin metabolic process;GO:0015889 cobalamin transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I5ZKA9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A122-1", "uniprot_id": [ { "id": "A0A8I6A122_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A122", "type": "external" } ], "mass": 20887.0, "length": 186, "protein_name": "TATA box-binding protein-like 1", "gene_name": "Tbpl1", "organism": "Rat", "refseq_name": "TATA box-binding protein-like 1", "refseq_ac": [ { "id": "NP_001120673", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001120673", "type": "external" } ], "gene_names_uniprotkb": "Tbpl1", "gene_names_refseq": "Tbpl1", "protein_names_uniprotkb": "TATA box-binding protein-like 1; TATA box-binding protein-related factor 2; TBP-like factor; TBP-related protein", "protein_names_refseq": "TATA box-binding protein-like 1; TATA box-binding protein-like protein 1; TBP-like 1", "tax_id": 10116, "disease": "", "pathway": " (rno:689030)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23374846;26446791", "class_list": "", "function": "Part of a specialized transcription system that mediates the transcription of most ribosomal proteins through the 5'-TCT-3' motif which is a core promoter element at these genes. Seems to also mediate the transcription of NF1. Does not bind the TATA box., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; These findings have indicated that overproduction of reactive oxygen species after testicular torsion-detorsion can damage testicular spermatogenesis by downregulation of TRF2 expression., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding;GO:0016251 RNA polymerase II general transcription initiation factor activity;GO:0140223 general transcription initiation factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005672 transcription factor TFIIA complex", "go_biological_process": "GO:0006352 DNA-templated transcription initiation;GO:0007283 spermatogenesis;GO:0001675 acrosome assembly;GO:0007289 spermatid nucleus differentiation;GO:0006235 dTTP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A8I6A122-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AAD8-1", "uniprot_id": [ { "id": "A0A8I6AAD8_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AAD8", "type": "external" } ], "mass": 52992.0, "length": 461, "protein_name": "Sorting nexin-4", "gene_name": "Snx4", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Snx4", "gene_names_refseq": "", "protein_names_uniprotkb": "Sorting nexin-4", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in the regulation of endocytosis and in several stages of intracellular trafficking. Plays a role in recycling endocytosed transferrin receptor and prevent its degradation. Involved in autophagosome assembly by regulating trafficking and recycling of phospholipid scramblase ATG9A., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005158 insulin receptor binding;GO:0005154 epidermal growth factor receptor binding;GO:0032266 phosphatidylinositol-3-phosphate binding;GO:0035091 phosphatidylinositol binding;GO:1990460 leptin receptor binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0031901 early endosome membrane", "go_biological_process": "GO:0015031 protein transport;GO:0032456 endocytic recycling;GO:1903595 positive regulation of histamine secretion by mast cell;GO:2000786 positive regulation of autophagosome assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6AAD8-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AS60-1", "uniprot_id": [ { "id": "A0A8I6AS60_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AS60", "type": "external" } ], "mass": 69438.0, "length": 639, "protein_name": "Eyes absent homolog", "gene_name": "Eya4", "organism": "Rat", "refseq_name": "eyes absent homolog 4 isoform X2", "refseq_ac": [ { "id": "XP_038959236", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038959236", "type": "external" } ], "gene_names_uniprotkb": "Eya4", "gene_names_refseq": "Eya4", "protein_names_uniprotkb": "Eyes absent homolog; 3.1.3.48", "protein_names_refseq": "eyes absent homolog 4 isoform X2", "tax_id": 10116, "disease": "dilated cardiomyopathy 1J (Disease Ontology:DOID:0110440); autosomal dominant nonsyndromic deafness 10 (Disease Ontology:DOID:0110542); sensorineural hearing loss (Disease Ontology:DOID:10003); otitis media (Disease Ontology:DOID:10754); dilated cardiomyopathy (Disease Ontology:DOID:12930); branchiootorenal syndrome (Disease Ontology:DOID:14702); eye disease (Disease Ontology:DOID:5614); congestive heart failure (Disease Ontology:DOID:6000)", "pathway": " (rno:292172); (R-RNO-5693565)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.1.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21", "type": "external" }, { "id": "3.1.3.18", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.18", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" }, { "id": "3.1.3.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.5", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006281 DNA repair;GO:0006351 DNA-templated transcription;GO:0007605 sensory perception of sound;GO:0042474 middle ear morphogenesis;GO:0048839 inner ear development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6AS60-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZM18-1", "uniprot_id": [ { "id": "A0A8I5ZM18_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZM18", "type": "external" } ], "mass": 47866.0, "length": 431, "protein_name": "Transmembrane protease serine", "gene_name": "Tmprss11c", "organism": "Rat", "refseq_name": "transmembrane protease, serine 11C isoform 1", "refseq_ac": [ { "id": "NP_001399454", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001399454", "type": "external" } ], "gene_names_uniprotkb": "Tmprss11c; Tmprss11b", "gene_names_refseq": "Hatl3; Tmprss11c", "protein_names_uniprotkb": "Transmembrane protease serine; 3.4.21.-", "protein_names_refseq": "airway trypsin-like 3; transmembrane protease, serine 11C isoform 1", "tax_id": 10116, "disease": "", "pathway": " (rno:408213)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0008236 serine-type peptidase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0043204 perikaryon", "go_biological_process": "GO:0016485 protein processing;GO:0006508 proteolysis;GO:0097264 self proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I5ZM18-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZNR8-1", "uniprot_id": [ { "id": "A0A8I5ZNR8_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZNR8", "type": "external" } ], "mass": 226691.0, "length": 1978, "protein_name": "Dedicator of cytokinesis protein 4", "gene_name": "Dock4", "organism": "Rat", "refseq_name": "dedicator of cytokinesis protein 4", "refseq_ac": [ { "id": "NP_001414020", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414020", "type": "external" } ], "gene_names_uniprotkb": "Dock4", "gene_names_refseq": "Dock4", "protein_names_uniprotkb": "Dedicator of cytokinesis protein 4", "protein_names_refseq": "dedicator of cytokinesis protein 4", "tax_id": 10116, "disease": "", "pathway": " (rno:366608); (R-RNO-9013149); (R-RNO-9013404); (R-RNO-9013408); (R-RNO-983231)", "pathway_count": 5, "publication_count": 5, "publication_id_list": "16641100;18615735;22673903;23536706;36882763", "class_list": "", "function": "A new function of the Rac activator Dock4 in dendritic morphogenesis in hippocampal neurons, [RefSeq, PubMed]; Direct targeting of DOCK4 by miRNA-181d in oxygen-glucose deprivation/reoxygenation-mediated neuronal injury. Publication Status: Online-Only, [RefSeq, PubMed]; Dock4 is highly concentrated in dendritic spines and implicated in spine formation via interaction with the actin-binding protein cortactin., [RefSeq, PubMed]; Functions as a guanine nucleotide exchange factor (GEF) that promotes the exchange of GDP to GTP, converting inactive GDP-bound small GTPases into their active GTP-bound form. Involved in regulation of adherens junction between cells. Plays a role in cell migration., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Has a higher guanine nucleotide exchange factor activity compared to other isoforms., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity;GO:0005096 GTPase activator activity;GO:0017124 SH3 domain binding;GO:0031267 small GTPase binding;GO:0030165 PDZ domain binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0043226 organelle;GO:0098978 glutamatergic synapse", "go_biological_process": "GO:0007264 small GTPase-mediated signal transduction;GO:0060326 cell chemotaxis;GO:1904754 positive regulation of vascular associated smooth muscle cell migration;GO:1904694 negative regulation of vascular associated smooth muscle contraction;GO:0150052 regulation of postsynapse assembly", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A8I5ZNR8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZYJ1-1", "uniprot_id": [ { "id": "A0A8I5ZYJ1_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZYJ1", "type": "external" } ], "mass": 348753.0, "length": 3266, "protein_name": "Snf2-related CREBBP activator protein", "gene_name": "Srcap", "organism": "Rat", "refseq_name": "helicase SRCAP", "refseq_ac": [ { "id": "NP_001413863", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001413863", "type": "external" } ], "gene_names_uniprotkb": "Srcap", "gene_names_refseq": "RGD1565642; Srcap", "protein_names_uniprotkb": "Snf2-related CREBBP activator protein", "protein_names_refseq": "helicase SRCAP-like; helicase SRCAP", "tax_id": 10116, "disease": "syndromic intellectual disability (Disease Ontology:DOID:0050888); developmental disorder of mental health (Disease Ontology:DOID:0060037); Floating-Harbor syndrome (Disease Ontology:DOID:0111358)", "pathway": " (rno:361652)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 10, "predicted_n_glycosites": 0, "predicted_o_glycosites": 10, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 10, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0004386 helicase activity;GO:0003713 transcription coactivator activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005634 nucleus;GO:0048471 perinuclear region of cytoplasm;GO:0016604 nuclear body;GO:0000812 Swr1 complex", "go_biological_process": "GO:0006325 chromatin organization;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0141156 cAMP/PKA signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I5ZYJ1-1", "record_type": "protein", "filter_code": "0000000.0000111.001000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZTN7-1", "uniprot_id": [ { "id": "A0A8I5ZTN7_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZTN7", "type": "external" } ], "mass": 68984.0, "length": 604, "protein_name": "Guanylate binding protein 5", "gene_name": "Gbp5", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Gbp5", "gene_names_refseq": "", "protein_names_uniprotkb": "Guanylate binding protein 5", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:362050); (R-RNO-9953170)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity;GO:0140678 molecular function inhibitor activity", "go_cellular_component": "GO:0031410 cytoplasmic vesicle;GO:0000139 Golgi membrane;GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0071346 cellular response to type II interferon;GO:0031347 regulation of defense response;GO:0032741 positive regulation of interleukin-18 production;GO:0051289 protein homotetramerization;GO:0051607 defense response to virus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I5ZTN7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZT33-1", "uniprot_id": [ { "id": "A0A8I5ZT33_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZT33", "type": "external" } ], "mass": 70909.0, "length": 651, "protein_name": "Vitrin", "gene_name": "Vit", "organism": "Rat", "refseq_name": "vitrin precursor", "refseq_ac": [ { "id": "NP_001418816", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001418816", "type": "external" } ], "gene_names_uniprotkb": "Vit", "gene_names_refseq": "RGD1564128; Vit", "protein_names_uniprotkb": "Vitrin", "protein_names_refseq": "vitrin precursor", "tax_id": 10116, "disease": "", "pathway": " (rno:313831)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Promotes matrix assembly and cell adhesiveness. Plays a role in spinal cord formation by regulating the proliferation and differentiation of neural stem cells., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005539 glycosaminoglycan binding", "go_cellular_component": "GO:0031012 extracellular matrix;GO:0005614 interstitial matrix", "go_biological_process": "GO:0007399 nervous system development;GO:0021510 spinal cord development;GO:0030198 extracellular matrix organization;GO:0010811 positive regulation of cell-substrate adhesion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I5ZT33-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5XZV4-1", "uniprot_id": [ { "id": "A0A8I5XZV4_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5XZV4", "type": "external" } ], "mass": 140394.0, "length": 1267, "protein_name": "Zinc finger, MYND-type containing 8", "gene_name": "Zmynd8", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Zmynd8", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger, MYND-type containing 8", "protein_names_refseq": "", "tax_id": 10116, "disease": "syndromic intellectual disability (Disease Ontology:DOID:0050888)", "pathway": " (R-RNO-9940951)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0019904 protein domain specific binding;GO:0003714 transcription corepressor activity;GO:0140015 histone H3K14ac reader activity;GO:0140109 histone H3K4me1 reader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0043197 dendritic spine", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0007399 nervous system development;GO:0098815 modulation of excitatory postsynaptic potential;GO:0030336 negative regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I5XZV4-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A6B6-1", "uniprot_id": [ { "id": "A0A8I6A6B6_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A6B6", "type": "external" } ], "mass": 109451.0, "length": 977, "protein_name": "Protein phosphatase 1 regulatory subunit", "gene_name": "Ppp1r12b", "organism": "Rat", "refseq_name": "protein phosphatase 1 regulatory subunit 12B isoform X3", "refseq_ac": [ { "id": "XP_006249938", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006249938", "type": "external" } ], "gene_names_uniprotkb": "Ppp1r12b", "gene_names_refseq": "Ppp1r12b", "protein_names_uniprotkb": "Protein phosphatase 1 regulatory subunit", "protein_names_refseq": "protein phosphatase 1 regulatory subunit 12B isoform X3", "tax_id": 10116, "disease": "", "pathway": " (rno:304813); (R-RNO-2565942); (R-RNO-5625740); (R-RNO-5627123)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "22673903;34502162", "class_list": "", "function": "Regulates myosin phosphatase activity. Augments Ca(2+) sensitivity of the contractile apparatus., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0019208 phosphatase regulator activity;GO:0017020 myosin phosphatase regulator activity;GO:0004857 enzyme inhibitor activity", "go_cellular_component": "GO:0001725 stress fiber;GO:0030018 Z disc;GO:0031672 A band;GO:0005737 cytoplasm", "go_biological_process": "GO:0007165 signal transduction;GO:0048812 neuron projection morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A8I6A6B6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K4D6-1", "uniprot_id": [ { "id": "A0A0G2K4D6_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K4D6", "type": "external" } ], "mass": 83854.0, "length": 723, "protein_name": "RUN and FYVE domain containing 2", "gene_name": "Rufy2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Rufy2", "gene_names_refseq": "", "protein_names_uniprotkb": "RUN and FYVE domain containing 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017124 SH3 domain binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K4D6-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0DX21-1", "uniprot_id": [ { "id": "S17A9_RAT", "url": "https://www.uniprot.org/uniprot/P0DX21", "type": "external" } ], "mass": 48638.0, "length": 447, "protein_name": "Voltage-gated purine nucleotide uniporter SLC17A9", "gene_name": "Slc17a9", "organism": "Rat", "refseq_name": "voltage-gated purine nucleotide uniporter SLC17A9", "refseq_ac": [ { "id": "NP_001102083", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102083", "type": "external" } ], "gene_names_uniprotkb": "Slc17a9", "gene_names_refseq": "RGD1311940; Slc17a9; VNUT", "protein_names_uniprotkb": "Voltage-gated purine nucleotide uniporter SLC17A9; Solute carrier family 17 member 9; VNUT; Vesicular nucleotide transporter", "protein_names_refseq": "Vesicular nucleotide transporter; solute carrier family 17 (vesicular nucleotide transporter), member 9; voltage-gated purine nucleotide uniporter SLC17A9", "tax_id": 10116, "disease": "porokeratosis (Disease Ontology:DOID:3805)", "pathway": " (rno:362287)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "18375752;21810784;23832620;24989000;25043192;31810015", "class_list": "", "function": "Results indicate that release of ATP from periodontal ligament cells via VNUT is important for nociceptive transduction during orthodontic treatment, [RefSeq, PubMed]; These results demonstrate that intestinal L cells express VNUT (vesicular nucleotide transporter )and suggest that L cells are purinergic in nature and secrete nucleotides., [RefSeq, PubMed]; These results suggest that VNUT plays a role in ATP accumulation in dorsal root ganglion neurons, [RefSeq, PubMed]; VNUT mediates transport of ATP into synaptic vesicles of hippocampal neurons, [RefSeq, PubMed]; Voltage-gated ATP nucleotide uniporter that can also transport the purine nucleotides ADP and GTP. Uses the membrane potential as the driving force to control ATP accumulation in lysosomes and secretory vesicles (PubMed:18375752). By controlling ATP storage in lysosomes, regulates ATP-dependent proteins of these organelles (By similarity). Also indirectly regulates the exocytosis of ATP through its import into lysosomes in astrocytes and secretory vesicles such as adrenal chromaffin granules, mucin granules and synaptic vesicles (PubMed:18375752)., [UniProtKB, UniProtKB, PubMed, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005347 ATP transmembrane transporter activity;GO:0015217 ADP transmembrane transporter activity;GO:0001409 guanine nucleotide transmembrane transporter activity;GO:0160042 purine nucleotide uniporter activity;GO:0015291 secondary active transmembrane transporter activity", "go_cellular_component": "GO:0030141 secretory granule;GO:0005765 lysosomal membrane;GO:0030658 transport vesicle membrane;GO:0042584 chromaffin granule membrane;GO:0098594 mucin granule", "go_biological_process": "GO:0015866 ADP transport;GO:1905146 lysosomal protein catabolic process;GO:1903790 guanine nucleotide transmembrane transport;GO:0015867 ATP transport;GO:1904669 ATP export", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P0DX21-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZYV7-1", "uniprot_id": [ { "id": "A0A8I5ZYV7_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZYV7", "type": "external" } ], "mass": 34683.0, "length": 312, "protein_name": "Large ribosomal subunit protein bL21m", "gene_name": "Mrpl21", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Mrpl21", "gene_names_refseq": "", "protein_names_uniprotkb": "Large ribosomal subunit protein bL21m", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:309140); (R-RNO-5389840); (R-RNO-5419276); (R-RNO-9937383)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005762 mitochondrial large ribosomal subunit;GO:0005739 mitochondrion", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I5ZYV7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZLL3-1", "uniprot_id": [ { "id": "A0A8I5ZLL3_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZLL3", "type": "external" } ], "mass": 155803.0, "length": 1402, "protein_name": "Rho/Rac guanine nucleotide exchange factor 18", "gene_name": "Arhgef18", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Arhgef18", "gene_names_refseq": "", "protein_names_uniprotkb": "Rho/Rac guanine nucleotide exchange factor 18", "protein_names_refseq": "", "tax_id": 10116, "disease": "retinitis pigmentosa 78 (Disease Ontology:DOID:0061113)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0045177 apical part of cell", "go_biological_process": "GO:0007264 small GTPase-mediated signal transduction;GO:0150105 protein localization to cell-cell junction;GO:0030036 actin cytoskeleton organization;GO:0008360 regulation of cell shape;GO:0051497 negative regulation of stress fiber assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I5ZLL3-1", "record_type": "protein", "filter_code": "0000000.0000110.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A5M6-1", "uniprot_id": [ { "id": "A0A8I6A5M6_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A5M6", "type": "external" } ], "mass": 73411.0, "length": 650, "protein_name": "Rho GTPase activating protein 25", "gene_name": "Arhgap25", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Arhgap25", "gene_names_refseq": "", "protein_names_uniprotkb": "Rho GTPase activating protein 25", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:500246); 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lung small cell carcinoma (Disease Ontology:DOID:5409); myocardial infarction (Disease Ontology:DOID:5844); hepatocellular carcinoma (Disease Ontology:DOID:684); malignant pleural mesothelioma (Disease Ontology:DOID:7474); colorectal cancer (Disease Ontology:DOID:9256); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (R-RNO-3214842)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "22673903;34122720", "class_list": "", "function": "MicroRNA-145-Mediated KDM6A Downregulation Enhances Neural Repair after Spinal Cord Injury via the NOTCH2/Abcb1a Axis. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 20, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.68", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.68", "type": "external" }, { "id": "1.14.11.65", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.65", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0071558 histone H3K27me2/H3K27me3 demethylase activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0042802 identical protein binding;GO:0031490 chromatin DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0035097 histone methyltransferase complex;GO:0044666 MLL3/4 complex", "go_biological_process": "GO:0003007 heart morphogenesis;GO:0072359 circulatory system development;GO:1904385 cellular response to angiotensin;GO:0048570 notochord morphogenesis;GO:1990859 cellular response to endothelin", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8I6A5T3-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A922-1", "uniprot_id": [ { "id": "A0A8I6A922_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A922", "type": "external" } ], "mass": 65951.0, "length": 607, "protein_name": "Cdk5 and Abl enzyme substrate 2", "gene_name": "Cables2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Cables2", "gene_names_refseq": "", "protein_names_uniprotkb": "Cdk5 and Abl enzyme substrate 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:311703)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, 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"go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0001701 in utero embryonic development;GO:0007369 gastrulation;GO:0030330 DNA damage response, signal transduction by p53 class mediator;GO:0010467 gene expression;GO:0051726 regulation of cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6A922-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AQL7-1", "uniprot_id": [ { "id": "A0A8I6AQL7_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AQL7", "type": "external" } ], "mass": 106761.0, "length": 976, "protein_name": "Serine/threonine-protein kinase Nek9", "gene_name": "Nek9", "organism": "Rat", "refseq_name": "serine/threonine-protein kinase Nek9", "refseq_ac": [ { "id": "NP_001100217", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100217", "type": "external" } ], "gene_names_uniprotkb": 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Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression. Phosphorylates NEK6 and NEK7 and stimulates their activity by releasing the autoinhibitory functions of Tyr-108 and Tyr-97 respectively., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 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"type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0019901 protein kinase binding;GO:0030295 protein kinase activator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005634 nucleus;GO:0005813 centrosome", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0051301 cell division;GO:0007346 regulation of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I6AQL7-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZNS2-1", "uniprot_id": [ { "id": "A0A8I5ZNS2_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZNS2", "type": "external" } ], "mass": 140296.0, "length": 1317, "protein_name": "Activating transcription factor 7 interacting protein", "gene_name": "Atf7ip", "organism": "Rat", "refseq_name": 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"go_cellular_component": "GO:0005634 nucleus;GO:0005667 transcription regulator complex;GO:0005654 nucleoplasm;GO:0016604 nuclear body", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I5ZNS2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6ABJ9-1", "uniprot_id": [ { "id": "A0A8I6ABJ9_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6ABJ9", "type": "external" } ], "mass": 62499.0, "length": 582, "protein_name": "YTH domain-containing family protein", "gene_name": "Ythdf2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ythdf2", "gene_names_refseq": "", "protein_names_uniprotkb": "YTH domain-containing family protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "disease of metabolism (Disease Ontology:DOID:0014667)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:1990247 N6-methyladenosine-containing RNA reader activity;GO:0062153 C5-methylcytidine-containing RNA reader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0000932 P-body;GO:0036464 cytoplasmic ribonucleoprotein granule", "go_biological_process": "GO:1903679 positive regulation of cap-independent translational initiation;GO:2000232 regulation of rRNA processing;GO:0030155 regulation of cell adhesion;GO:0043488 regulation of mRNA stability;GO:1902036 regulation of hematopoietic stem cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I6ABJ9-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A9C9-1", "uniprot_id": [ { "id": "A0A8I6A9C9_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A9C9", "type": "external" } ], "mass": 29794.0, "length": 278, "protein_name": "Acrosomal vesicle protein 1", "gene_name": "Acrv1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Acrv1", "gene_names_refseq": "", "protein_names_uniprotkb": "Acrosomal vesicle protein 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0001669 acrosomal vesicle", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6A9C9-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K0X0-1", "uniprot_id": [ { "id": "A0A0G2K0X0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K0X0", "type": "external" } ], "mass": 30459.0, "length": 263, "protein_name": "Tafazzin family protein", "gene_name": "Tafazzin", "organism": "Rat", "refseq_name": "tafazzin isoform X1", "refseq_ac": [ { "id": "XP_038955846", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038955846", "type": "external" } ], "gene_names_uniprotkb": "Tafazzin; TAZ", "gene_names_refseq": "Tafazzin; Taz", "protein_names_uniprotkb": "Tafazzin family protein", "protein_names_refseq": "tafazzin isoform X1", "tax_id": 10116, "disease": "Barth syndrome (Disease Ontology:DOID:0050476); visceral heterotaxy (Disease Ontology:DOID:0050545); cardiomyopathy (Disease Ontology:DOID:0050700); dilated cardiomyopathy (Disease Ontology:DOID:12930)", "pathway": " (R-RNO-1482798)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acyltransferase which is required to remodel newly synthesized phospholipid cardiolipin, a key component of the mitochondrial inner membrane. Required for the initiation of mitophagy. Required to ensure progression of spermatocytes through meiosis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016746 acyltransferase activity;GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005743 mitochondrial inner membrane;GO:0005739 mitochondrion;GO:0005758 mitochondrial intermembrane space;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0006644 phospholipid metabolic process;GO:2001171 positive regulation of ATP biosynthetic process;GO:1900210 positive regulation of cardiolipin metabolic process;GO:0035965 cardiolipin acyl-chain remodeling;GO:0042407 cristae formation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K0X0-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6APJ0-1", "uniprot_id": [ { "id": "A0A8I6APJ0_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6APJ0", "type": "external" } ], "mass": 15822.0, "length": 141, "protein_name": "U6 snRNA-associated Sm-like protein LSm4", "gene_name": "Lsm4", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Lsm4; LSM4", "gene_names_refseq": "", "protein_names_uniprotkb": "U6 snRNA-associated Sm-like protein LSm4", "protein_names_refseq": "", "tax_id": 10116, "disease": "cancer (Disease Ontology:DOID:162); atherosclerosis (Disease Ontology:DOID:1936)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Binds specifically to the 3'-terminal U-tract of U6 snRNA., [UniProtKB, UniProtKB]; Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0042731 PH domain binding", "go_cellular_component": "GO:0005681 spliceosomal complex;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0006396 RNA processing;GO:0000956 nuclear-transcribed mRNA catabolic process;GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6APJ0-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AFQ6-1", "uniprot_id": [ { "id": "A0A8I6AFQ6_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AFQ6", "type": "external" } ], "mass": 35246.0, "length": 317, "protein_name": "Olfactory receptor", "gene_name": "Or52ae8", "organism": "Rat", "refseq_name": "olfactory receptor Olr115", "refseq_ac": [ { "id": "NP_001000152", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000152", "type": "external" } ], "gene_names_uniprotkb": "Or52ae8", "gene_names_refseq": "Olr115; Or52ae8; ratchr1-161443812-161442859_ORF", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 115; olfactory receptor Olr115; olfactory receptor gene Olr115", "tax_id": 10116, "disease": "", "pathway": " (rno:293253)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6AFQ6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AI28-1", "uniprot_id": [ { "id": "A0A8I6AI28_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AI28", "type": "external" } ], "mass": 54666.0, "length": 477, "protein_name": "Oxysterol-binding protein", "gene_name": "Osbpl2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Osbpl2", "gene_names_refseq": "", "protein_names_uniprotkb": "Oxysterol-binding protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "autosomal dominant nonsyndromic deafness 67 (Disease Ontology:DOID:0110588); 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Tcam1p", "gene_names_refseq": "Tcam1p; Tcam1", "protein_names_uniprotkb": "Intercellular adhesion molecule 1", "protein_names_refseq": "testicular cell adhesion molecule 1 homolog; testicular cell adhesion molecule 1 precursor", "tax_id": 10116, "disease": "dilated cardiomyopathy (Disease Ontology:DOID:12930)", "pathway": " (rno:59305)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cell adhesion molecule that functions as a receptor ligand of the signaling receptor ITGAL:ITGB2/LFA-1 (lymphocyte-function associated (LFA) molecule 1) ensuring leukocyte cell-cell adhesion, by providing a calibrated system to namely adjust T-cell killing to the antigen stimulation strength. Also functions as a ligand receptor of the signaling receptor ITGAM:ITGB2/MAC-1 ensuring adhesion between stimulated neutrophils and stimulated endothelial cells. During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. Promotes cell aggregation in epithelial cells through interaction with MUC1., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9Z133", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0006955 immune response;GO:0071333 cellular response to glucose stimulus;GO:0007159 leukocyte cell-cell adhesion;GO:0050900 leukocyte migration;GO:0002252 immune effector process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A6HK25-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A6HMU0-1", "uniprot_id": [ { "id": "A6HMU0_RAT", "url": "https://www.uniprot.org/uniprot/A6HMU0", "type": "external" } ], "mass": 35556.0, "length": 315, "protein_name": "Olfactory receptor", "gene_name": "Or5ak25", "organism": "Rat", "refseq_name": "olfactory receptor Olr442", "refseq_ac": [ { "id": "NP_001000284", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000284", "type": "external" } ], "gene_names_uniprotkb": "Or5ak25", "gene_names_refseq": "Olr442; Or5ak25; TB 567; ratchr3-68554730-68553783_ORF", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 442; olfactory receptor Olr442; olfactory receptor gene Olr442; taste bud receptor protein TB 567", "tax_id": 10116, "disease": "", "pathway": " (rno:295713)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q62943", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A6HMU0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A6JUI2-1", "uniprot_id": [ { "id": "A6JUI2_RAT", "url": "https://www.uniprot.org/uniprot/A6JUI2", "type": "external" } ], "mass": 34622.0, "length": 311, "protein_name": "Olfactory receptor", "gene_name": "Or1n1b", "organism": "Rat", "refseq_name": "olfactory receptor Olr416", "refseq_ac": [ { "id": "NP_001000387", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000387", "type": "external" } ], "gene_names_uniprotkb": "Or1n1b", "gene_names_refseq": "Olr416; Or1n1b; TB 334", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 416; olfactory receptor Olr416; olfactory receptor gene Olr416; taste bud receptor protein TB 334", "tax_id": 10116, "disease": "", "pathway": " (rno:296678)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1M9D5;Q62942", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A6JUI2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A6KT88-1", "uniprot_id": [ { "id": "A6KT88_RAT", "url": "https://www.uniprot.org/uniprot/A6KT88", "type": "external" } ], "mass": 17605.0, "length": 160, "protein_name": "Immediate early response 3", "gene_name": "Ier3", "organism": "Rat", "refseq_name": "radiation-inducible immediate-early gene IEX-1", "refseq_ac": [ { "id": "NP_997670", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997670", "type": "external" } ], "gene_names_uniprotkb": "Ier3", "gene_names_refseq": "Dif2; Ier3; Iex1; Ler3; Prg1", "protein_names_uniprotkb": "Immediate early response 3", "protein_names_refseq": "radiation-inducible immediate-early gene IEX-1", "tax_id": 10116, "disease": "T-cell non-Hodgkin lymphoma (Disease Ontology:DOID:0081312)", "pathway": " (rno:294235)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "27890615", "class_list": "", "function": "Analysis of consensus EGR-binding elements (EBEs) showed that the immediate early response 3 gene (IER3) is a novel transcriptional target gene of EGR2 as confirmed by the luciferase assay, electrophoretic mobility-shift assay (EMSA), chromatin immunoprecipitation (ChIP), and western blot analysis., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6MG18", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion", "go_biological_process": "GO:0046822 regulation of nucleocytoplasmic transport;GO:0050728 negative regulation of inflammatory response;GO:0006974 DNA damage response;GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage;GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A6KT88-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6XPU4-1", "uniprot_id": [ { "id": "FCG3A_RAT", "url": "https://www.uniprot.org/uniprot/Q6XPU4", "type": "external" } ], "mass": 28168.0, "length": 249, "protein_name": "Low affinity immunoglobulin gamma Fc region receptor III-A", "gene_name": "Fcgr3a", "organism": "Rat", "refseq_name": "low affinity immunoglobulin gamma Fc region receptor III-A precursor", "refseq_ac": [ { "id": "NP_997486", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997486", "type": "external" } ], "gene_names_uniprotkb": "Fcgr3a; Fcgr4", "gene_names_refseq": "CD16-2; Fcgr3a; Fcgr4", "protein_names_uniprotkb": "Low affinity immunoglobulin gamma Fc region receptor III-A; CD16-2; FcgammaRIV; IgG Fc receptor III-A", "protein_names_refseq": "Fc fragment of IgG intermediate affinity IV receptor; Fc fragment of IgG receptor IIIa; Fc fragment of IgG, low affinity IIIa, receptor for (CD16); Fc gamma receptor IIIa; IgG Fc receptor III-A; fcgammaRIV; low affinity immunoglobulin gamma Fc region receptor III-A precursor; low affinity immunoglobulin gamma Fc region receptor III-A; transmembrane receptor FcgammaRIII-X", "tax_id": 10116, "disease": "myelodysplastic syndrome (Disease Ontology:DOID:0050908); lymphoplasmacytic lymphoma (Disease Ontology:DOID:0060901); lupus nephritis (Disease Ontology:DOID:0080162); graft-versus-host disease (Disease Ontology:DOID:0081267); immunodeficiency 20 (Disease Ontology:DOID:0111941); allergic disease (Disease Ontology:DOID:1205); Behcet's disease (Disease Ontology:DOID:13241); temporal arteritis (Disease Ontology:DOID:13375); polyneuropathy (Disease Ontology:DOID:1389); thrombocytopenia due to platelet alloimmunization (Disease Ontology:DOID:1587); epilepsy (Disease Ontology:DOID:1826); multiple sclerosis (Disease Ontology:DOID:2377); asthma (Disease Ontology:DOID:2841); IgA glomerulonephritis (Disease Ontology:DOID:2986); coronary artery disease (Disease Ontology:DOID:3393); allergic rhinitis (Disease Ontology:DOID:4481); anti-basement membrane glomerulonephritis (Disease Ontology:DOID:4780); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); pneumonia (Disease Ontology:DOID:552); lymphopenia (Disease Ontology:DOID:614); myositis (Disease Ontology:DOID:633); ankylosing spondylitis (Disease Ontology:DOID:7147); rheumatoid arthritis (Disease Ontology:DOID:7148); arthritis (Disease Ontology:DOID:848); Crohn's disease (Disease Ontology:DOID:8778); autoimmune thrombocytopenic purpura (Disease Ontology:DOID:8924); systemic lupus erythematosus (Disease Ontology:DOID:9074)", "pathway": " (rno:304966); (R-RNO-163125); (R-RNO-6798695)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "34485821", "class_list": "", "function": "Receptor for the invariable Fc fragment of immunoglobulin gamma (IgG). Binds with intermediate affinity to both IgG2a and IgG2b. Can bind to IgG2a and IgG2b monomers. Does not display binding to IgG1 or IgG3 (By similarity). Recognizes neutralizing virus-specific IgGs displayed on the cell surface of infected cells and triggers antibody-dependent cellular cytotoxicity (ADCC). Confers protection to lethal influenza virus infection (By similarity). On splenic dendritic cells, uptakes antigen immune complexes and efficiently divert them into MHC class I and II antigen presentation pathways to provide for superior priming of CD4-positive and CD8-positive T cell immune responses (By similarity). Mediates neutrophil activation by IgG complexes redundantly with FCGR2A (By similarity). Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a (By similarity). Also acts as a receptor for the Fc region of immunoglobulin epsilon (IgE). Binds with low affinity to both the a and b allotypes of IgE. Has also been shown to bind to IgE allotype a only but not to allotype b. Binds aggregated IgE but not the monomeric form and bound monomeric IgG is readily displaced by IgE complexes. Binding to IgE promotes macrophage-mediated phagocytosis, antigen presentation to T cells, production of pro-inflammatory cytokines and the late phase of cutaneous allergic reactions (By similarity). Mediates enhanced ADCC in response to afucosylated IgGs (PubMed:34485821)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 27, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "A0A0B4J2J1", "ec_number_list": [], "go_molecular_function": "GO:0019767 IgE receptor activity;GO:0019863 IgE binding;GO:0019864 IgG binding;GO:0019770 IgG receptor activity;GO:0019772 low-affinity IgG receptor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0009897 external side of plasma membrane;GO:0033001 Fc-gamma receptor III complex", "go_biological_process": "GO:0038094 Fc-gamma receptor signaling pathway;GO:0002468 dendritic cell antigen processing and presentation;GO:0007166 cell surface receptor signaling pathway;GO:0019722 calcium-mediated signaling;GO:0045780 positive regulation of bone resorption", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q6XPU4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5Y0Y2-1", "uniprot_id": [ { "id": "A0A8I5Y0Y2_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5Y0Y2", "type": "external" } ], "mass": 106033.0, "length": 986, "protein_name": "DNA damage inducible 1 homolog 2", "gene_name": "Ddi2", "organism": "Rat", "refseq_name": "protein DDI1 homolog 2 isoform X1", "refseq_ac": [ { "id": "XP_006239367", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006239367", "type": "external" } ], "gene_names_uniprotkb": "Ddi2", "gene_names_refseq": "Ddi2; RGD1311815", "protein_names_uniprotkb": "DNA damage inducible 1 homolog 2", "protein_names_refseq": "protein DDI1 homolog 2 isoform X1", "tax_id": 10116, "disease": "obesity (Disease Ontology:DOID:9970)", "pathway": " (rno:313668)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0043130 ubiquitin binding;GO:0004190 aspartic-type endopeptidase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0015031 protein transport;GO:0016485 protein processing;GO:0031647 regulation of protein stability;GO:0010498 proteasomal protein catabolic process;GO:0097752 regulation of DNA stability", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I5Y0Y2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5Y7I2-1", "uniprot_id": [ { "id": "A0A8I5Y7I2_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5Y7I2", "type": "external" } ], "mass": 35874.0, "length": 327, "protein_name": "Potassium channel tetramerization domain containing 12", "gene_name": "Kctd12", "organism": "Rat", "refseq_name": "BTB/POZ domain-containing protein KCTD12", "refseq_ac": [ { "id": "NP_001386444", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386444", "type": "external" } ], "gene_names_uniprotkb": "Kctd12", "gene_names_refseq": "Kctd12", "protein_names_uniprotkb": "Potassium channel tetramerization domain containing 12", "protein_names_refseq": "BTB/POZ domain-containing protein KCTD12; potassium channel tetramerisation domain containing 12", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "27073217", "class_list": "", "function": "Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization., [UniProtKB, UniProtKB]; Study highlights that GABABRs differentially control cholecystokinin-expressing interneuron subtypes, and the kinetics and desensitization of GABABR-mediated currents are modulated by KCTD12 proteins, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, 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0, "publication_id_list": "", "class_list": "", "function": "E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby restricting the size of the intestinal stem cell zone. Along with RSPO2 and RNF43, constitutes a master switch that governs limb specification., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" } ], "go_molecular_function": "GO:0005109 frizzled binding;GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway;GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0016055 Wnt signaling pathway;GO:0016567 protein ubiquitination;GO:0030178 negative regulation of Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I5ZKZ0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZL56-1", "uniprot_id": [ { "id": "A0A8I5ZL56_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZL56", "type": "external" } ], "mass": 30309.0, "length": 276, "protein_name": "E4 promoter-binding protein 4", "gene_name": "Nfilz", "organism": "Rat", "refseq_name": "NFIL3 like protein", "refseq_ac": [ { "id": "NP_001388159", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001388159", "type": "external" } ], "gene_names_uniprotkb": "Nfilz", "gene_names_refseq": "Nfilz", "protein_names_uniprotkb": "E4 promoter-binding protein 4", "protein_names_refseq": "NFIL3 like protein; nuclear factor, interleukin 3, regulated-like", "tax_id": 10116, "disease": "", "pathway": " (rno:102546838)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts. Represses transcriptional activity of PER1. Represses transcriptional activity of PER2 via the B-site on the promoter. Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF). Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock. Protects pro-B cells from programmed cell death. Represses the transcription of CYP2A5. Positively regulates the expression and activity of CES2 by antagonizing the repressive action of NR1D1 on CES2. 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The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. 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Interaction with YTHDC1, a RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, promotes recruitment of SRSF3 to its mRNA-binding elements adjacent to m6A sites within exons. Also functions as an adapter involved in mRNA nuclear export. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA-binding activity. Involved in nuclear export of m6A-containing mRNAs via interaction with YTHDC1: interaction with YTHDC1 facilitates m6A-containing mRNA-binding to both SRSF3 and NXF1, promoting mRNA nuclear export., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:1990825 sequence-specific mRNA binding;GO:0003723 RNA binding;GO:0003729 mRNA binding;GO:0043274 phospholipase binding;GO:0070878 primary miRNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0016607 nuclear speck", "go_biological_process": "GO:0006406 mRNA export from nucleus;GO:1990830 cellular response to leukemia inhibitory factor;GO:0048024 regulation of mRNA splicing, via spliceosome;GO:0031053 primary miRNA processing;GO:0000381 regulation of alternative mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I6A2P1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A419-1", "uniprot_id": [ { "id": "A0A8I6A419_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A419", "type": "external" } ], "mass": 14920.0, "length": 141, "protein_name": "Similar to human chromosome 3 open reading frame 86", "gene_name": "C8h3orf86", "organism": "Rat", "refseq_name": "similar to human chromosome 3 open reading frame 86", "refseq_ac": [ { "id": "NP_001417611", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417611", "type": "external" } ], "gene_names_uniprotkb": "C8h3orf86", "gene_names_refseq": "C8h3orf86", "protein_names_uniprotkb": "Similar to human chromosome 3 open reading frame 86", "protein_names_refseq": "chromosome 8 C3orf86 homolog; similar to human chromosome 3 open reading frame 86; uncharacterized protein C3orf86 homolog; uncharacterized protein C8h3orf86", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6A419-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A4C1-1", "uniprot_id": [ { "id": "A0A8I6A4C1_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A4C1", "type": "external" } ], "mass": 36745.0, "length": 350, "protein_name": "RRM domain-containing protein", "gene_name": "ENSRNOG00000063783", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ENSRNOG00000063783", "gene_names_refseq": "", "protein_names_uniprotkb": "RRM domain-containing protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003730 mRNA 3'-UTR binding", "go_cellular_component": "GO:0071013 catalytic step 2 spliceosome", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6A4C1-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A5P2-1", "uniprot_id": [ { "id": "A0A8I6A5P2_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A5P2", "type": "external" } ], "mass": 18250.0, "length": 167, "protein_name": "Modulator of smoothened protein", "gene_name": "Mosmo", "organism": "Rat", "refseq_name": "modulator of smoothened protein precursor", "refseq_ac": [ { "id": "NP_001388691", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001388691", "type": "external" } ], "gene_names_uniprotkb": "Mosmo", "gene_names_refseq": "Mosmo", "protein_names_uniprotkb": "Modulator of smoothened protein; Attenuator of hedgehog", "protein_names_refseq": "modulator of smoothened protein precursor; uncharacterized protein C16orf52 homolog", "tax_id": 10116, "disease": "chromosome 16p12.1 deletion syndrome (Disease Ontology:DOID:0060399)", "pathway": " (rno:102547219)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a negative regulator of hedgehog signaling probably by promoting internalization and subsequent degradation of smoothened protein (SMO) present in the ciliary membrane. Plays a role in sonic hedgehog (SHH)-induced spinal neural progenitor cells differentiation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0060170 ciliary membrane", "go_biological_process": "GO:0060972 left/right pattern formation;GO:0001701 in utero embryonic development;GO:0007507 heart development;GO:0030324 lung development;GO:0030326 embryonic limb morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6A5P2-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A6Q5-1", "uniprot_id": [ { "id": "A0A8I6A6Q5_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A6Q5", "type": "external" } ], "mass": 81413.0, "length": 737, "protein_name": "KIAA1958 homolog", "gene_name": "Kiaa1958", "organism": "Rat", "refseq_name": "uncharacterized protein KIAA1958 homolog isoform X1", "refseq_ac": [ { "id": "XP_063143105", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063143105", "type": "external" } ], "gene_names_uniprotkb": "Kiaa1958; RGD1310951", "gene_names_refseq": "Kiaa1958; RGD1310951", "protein_names_uniprotkb": "KIAA1958 homolog", "protein_names_refseq": "uncharacterized protein KIAA1958 homolog isoform X1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6A6Q5-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A6W9-1", "uniprot_id": [ { "id": "A0A8I6A6W9_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A6W9", "type": "external" } ], "mass": 122029.0, "length": 1093, "protein_name": "Uncharacterized LOC134482685", "gene_name": "LOC134482685", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LOC134482685", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized LOC134482685", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6A6W9-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A6Y9-1", "uniprot_id": [ { "id": "A0A8I6A6Y9_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A6Y9", "type": "external" } ], "mass": 26632.0, "length": 238, "protein_name": "RNA-binding protein PNO1", "gene_name": "ENSRNOG00000066543", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ENSRNOG00000066543", "gene_names_refseq": "", "protein_names_uniprotkb": "RNA-binding protein PNO1; 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During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Positively regulates dimethylation of two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6A6Y9-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A7B0-1", "uniprot_id": [ { "id": "A0A8I6A7B0_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A7B0", "type": "external" } ], "mass": 24097.0, "length": 212, "protein_name": "Cd300 molecule-like family member D like 1", "gene_name": "Cd300ldl1", "organism": "Rat", "refseq_name": "CMRF35-like molecule 5", "refseq_ac": [ { 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"reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0002757 immune response-activating signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6A7B0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AAN3-1", "uniprot_id": [ { "id": "A0A8I6AAN3_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AAN3", "type": "external" } ], "mass": 87329.0, "length": 795, "protein_name": "Delta-1-pyrroline-5-carboxylate synthase", "gene_name": "Aldh18a1", "organism": "Rat", "refseq_name": "delta-1-pyrroline-5-carboxylate synthase isoform 1", "refseq_ac": [ { "id": "NP_001101994", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101994", "type": "external" } ], "gene_names_uniprotkb": "Aldh18a1", "gene_names_refseq": "Aldh18a1; Pycs", "protein_names_uniprotkb": "Delta-1-pyrroline-5-carboxylate synthase; Gamma-glutamyl kinase; Glutamate-5-semialdehyde dehydrogenase; Glutamyl-gamma-semialdehyde dehydrogenase", "protein_names_refseq": "delta-1-pyrroline-5-carboxylate synthase isoform 1; delta-1-pyrroline-5-carboxylate synthase; pyrroline-5-carboxylate synthetase 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}, { "id": "2.6.99.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.99.-", "type": "external" } ], "go_molecular_function": "GO:0051287 NAD binding;GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6AAX6-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AB90-1", "uniprot_id": [ { "id": "A0A8I6AB90_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AB90", "type": "external" } ], "mass": 61798.0, "length": 572, "protein_name": "Forkhead box N4", "gene_name": "Foxn4", "organism": "Rat", "refseq_name": "forkhead box protein N4", "refseq_ac": [ { "id": "NP_001376188", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376188", "type": "external" } ], 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The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated with ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0030663 COPI-coated vesicle membrane;GO:0005794 Golgi apparatus;GO:0030137 COPI-coated vesicle;GO:0030126 COPI vesicle coat", "go_biological_process": "GO:0015031 protein transport;GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0099612 protein localization to axon;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006891 intra-Golgi vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I6A9R8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AL84-1", "uniprot_id": [ { "id": "A0A8I6AL84_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AL84", "type": "external" } ], "mass": 148015.0, "length": 1358, "protein_name": "KN motif and ankyrin repeat domains 1", "gene_name": "Kank1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Kank1", "gene_names_refseq": "", "protein_names_uniprotkb": "KN motif and ankyrin repeat domains 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "spastic quadriplegic cerebral palsy 2 (Disease Ontology:DOID:0081360); 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LRRGT00104", "protein_names_uniprotkb": "B-cell scaffold protein with ankyrin repeats", "protein_names_refseq": "B-cell scaffold protein with ankyrin repeats isoform X3", "tax_id": 10116, "disease": "diffuse scleroderma (Disease Ontology:DOID:1580); systemic scleroderma (Disease Ontology:DOID:418); autoimmune thyroiditis (Disease Ontology:DOID:7188); psoriasis (Disease Ontology:DOID:8893); systemic lupus erythematosus (Disease Ontology:DOID:9074); type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0002020 protease binding;GO:0005102 signaling receptor binding;GO:0035591 signaling adaptor activity;GO:0043274 phospholipase binding;GO:1990782 protein tyrosine kinase binding", "go_cellular_component": "GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0007165 signal transduction;GO:0043410 positive regulation of MAPK cascade;GO:0032715 negative regulation of interleukin-6 production;GO:0042113 B cell activation;GO:0009617 response to bacterium", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I6AIR4-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F7EZ61-1", "uniprot_id": [ { "id": "F7EZ61_RAT", "url": "https://www.uniprot.org/uniprot/F7EZ61", "type": "external" } ], "mass": 53685.0, "length": 475, "protein_name": "BTB domain containing 10", "gene_name": "Btbd10", "organism": "Rat", "refseq_name": "BTB/POZ domain-containing protein 10 isoform a", "refseq_ac": [ { "id": "NP_001386330", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386330", "type": "external" } ], "gene_names_uniprotkb": "Btbd10", "gene_names_refseq": "Btbd10; RGD1306301", "protein_names_uniprotkb": "BTB domain containing 10", "protein_names_refseq": "BTB (POZ) domain containing 10; BTB/POZ domain-containing protein 10 isoform a; BTB/POZ domain-containing protein 10; K+ channel tetramerization protein", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "23330007;23564125", "class_list": "", "function": "Decreased GMRP1(BTBD10)-mediated Akt pathway contributed to cell apoptosis in hemorrhagic side, suggesting that GMRP1 played an important role in brain damage after intracerebral hemorrhage., [RefSeq, PubMed]; The results of this study showed that a decreased GMRP1-mediated Akt pathway contributed to cell apoptosis on the hemorrhagic side, suggesting that GMRP1 plays an important role in brain damage after intracerebral hemorrhage in rat model., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005654 nucleoplasm;GO:0001650 fibrillar center", "go_biological_process": "GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F7EZ61-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6G1L6-1", "uniprot_id": [ { "id": "A0A8I6G1L6_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6G1L6", "type": "external" } ], "mass": 338388.0, "length": 3011, "protein_name": "FRY microtubule binding protein", "gene_name": "Fry", "organism": "Rat", "refseq_name": "protein furry homolog", "refseq_ac": [ { "id": "NP_001163869", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163869", "type": "external" } ], "gene_names_uniprotkb": "Fry", "gene_names_refseq": "Fry; RGD1307034", "protein_names_uniprotkb": "FRY microtubule binding protein", "protein_names_refseq": "furry homolog; protein furry homolog", "tax_id": 10116, "disease": "syndromic intellectual disability (Disease Ontology:DOID:0050888)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004857 enzyme inhibitor activity", "go_cellular_component": "GO:0005938 cell cortex;GO:0030427 site of polarized growth", "go_biological_process": "GO:0000902 cell morphogenesis;GO:1904428 negative regulation of tubulin deacetylation;GO:0031175 neuron projection development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I6G1L6-1", "record_type": "protein", "filter_code": "0000000.0000110.001000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AG83-1", "uniprot_id": [ { "id": "A0A8I6AG83_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AG83", "type": "external" } ], "mass": 33213.0, "length": 303, "protein_name": "Ribonuclease P/MRP subunit p30", "gene_name": "Rpp30", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Rpp30", "gene_names_refseq": "", "protein_names_uniprotkb": "Ribonuclease P/MRP subunit p30", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:685332); (R-RNO-6791226)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004526 ribonuclease P activity;GO:0033204 ribonuclease P RNA binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0030681 multimeric ribonuclease P complex;GO:0005634 nucleus;GO:0000172 ribonuclease MRP complex;GO:0005730 nucleolus;GO:0005655 nucleolar ribonuclease P complex", "go_biological_process": "GO:0001682 tRNA 5'-leader removal;GO:0008033 tRNA processing;GO:0006364 rRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6AG83-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AKZ9-1", "uniprot_id": [ { "id": "A0A8I6AKZ9_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AKZ9", "type": "external" } ], "mass": 42281.0, "length": 376, "protein_name": "Beta-centractin", "gene_name": "Actr1b", "organism": "Rat", "refseq_name": "beta-centractin", "refseq_ac": [ { "id": "NP_001034117", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034117", "type": "external" } ], "gene_names_uniprotkb": "Actr1b", "gene_names_refseq": "Actr1b", "protein_names_uniprotkb": "Beta-centractin; Actin-related protein 1B", "protein_names_refseq": "ARP1 actin related protein 1 homolog B; ARP1 actin-related protein 1 homolog B, centractin beta; beta-centractin", "tax_id": 10116, "disease": "", "pathway": " (rno:316333); (R-RNO-2132295); (R-RNO-6798695)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005200 structural constituent of cytoskeleton;GO:0005524 ATP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005869 dynactin complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6AKZ9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6G3L4-1", "uniprot_id": [ { "id": "A0A8I6G3L4_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6G3L4", "type": "external" } ], "mass": 65607.0, "length": 579, "protein_name": "Mucolipin TRP cation channel 1", "gene_name": "Mcoln1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Mcoln1", "gene_names_refseq": "", "protein_names_uniprotkb": "Mucolipin TRP cation channel 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "Lisch epithelial corneal dystrophy (Disease Ontology:DOID:0060450); mucolipidosis type IV (Disease Ontology:DOID:0080490); glycoproteinosis (Disease Ontology:DOID:3343)", "pathway": " (rno:288371); (R-RNO-3295583); (R-RNO-917977)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0005261 monoatomic cation channel activity;GO:0072345 NAADP-sensitive calcium-release channel activity;GO:0005262 calcium channel activity;GO:0042802 identical protein binding;GO:0005267 potassium channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0010008 endosome membrane;GO:0097708 intracellular vesicle;GO:0016020 membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0097352 autophagosome maturation;GO:0090382 phagosome maturation;GO:0034755 iron ion transmembrane transport;GO:0051289 protein homotetramerization;GO:0071277 cellular response to calcium ion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I6G3L4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6G358-1", "uniprot_id": [ { "id": "A0A8I6G358_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6G358", "type": "external" } ], "mass": 84256.0, "length": 740, "protein_name": "F-BAR and double SH3 domains protein 2", "gene_name": "Fchsd2", "organism": "Rat", "refseq_name": "F-BAR and double SH3 domains protein 2", "refseq_ac": [ { "id": "NP_001382671", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382671", "type": "external" } ], "gene_names_uniprotkb": "Fchsd2", "gene_names_refseq": "Fchsd2", "protein_names_uniprotkb": "F-BAR and double SH3 domains protein 2; Protein nervous wreck 1; SH3 multiple domains protein 3", "protein_names_refseq": "F-BAR and double SH3 domains protein 2; FCH and double SH3 domains protein 2", "tax_id": 10116, "disease": "", "pathway": " (rno:308864)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Adapter protein that plays a role in endocytosis via clathrin-coated pits. Contributes to the internalization of cell surface receptors, such as integrin ITGB1 and transferrin receptor. Promotes endocytosis of EGFR in cancer cells, and thereby contributes to the down-regulation of EGFR signaling. Recruited to clathrin-coated pits during a mid-to-late stage of assembly, where it is required for normal progress from U-shaped intermediate stage pits to terminal, omega-shaped pits. Binds to membranes enriched in phosphatidylinositol 3,4-bisphosphate or phosphatidylinositol 3,4,5-trisphosphate. When bound to membranes, promotes actin polymerization via its interaction with WAS and/or WASL which leads to the activation of the Arp2/3 complex. Does not promote actin polymerisation in the absence of membranes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008289 lipid binding;GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding;GO:0043325 phosphatidylinositol-3,4-bisphosphate binding", "go_cellular_component": "GO:0042995 cell projection;GO:0005886 plasma membrane;GO:0005905 clathrin-coated pit;GO:0031594 neuromuscular junction;GO:0055037 recycling endosome", "go_biological_process": "GO:0030838 positive regulation of actin filament polymerization;GO:0007274 neuromuscular synaptic transmission;GO:0015031 protein transport;GO:0061024 membrane organization;GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I6G358-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6GM39-1", "uniprot_id": [ { "id": "A0A8I6GM39_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6GM39", "type": "external" } ], "mass": 177642.0, "length": 1594, "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "Topbp1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Topbp1", "gene_names_refseq": "", "protein_names_uniprotkb": "DNA topoisomerase 2-binding protein 1; DNA topoisomerase II-beta-binding protein 1; DNA topoisomerase II-binding protein 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-5685938); (R-RNO-5693607); (R-RNO-6804756); (R-RNO-69473)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0140463 chromatin-protein adaptor activity;GO:0042802 identical protein binding;GO:0043539 protein serine/threonine kinase activator activity;GO:0140031 phosphorylation-dependent protein binding", "go_cellular_component": "GO:0005813 centrosome;GO:0070532 BRCA1-B complex;GO:0000794 condensed nuclear chromosome;GO:0005654 nucleoplasm;GO:0016604 nuclear body", "go_biological_process": "GO:0006281 DNA repair;GO:0007095 mitotic G2 DNA damage checkpoint signaling;GO:0006270 DNA replication initiation;GO:0033314 mitotic DNA replication checkpoint signaling;GO:1990166 protein localization to site of double-strand break", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6GM39-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AIZ7-1", "uniprot_id": [ { "id": "A0A8I6AIZ7_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AIZ7", "type": "external" } ], "mass": 46227.0, "length": 409, "protein_name": "DEP domain-containing mTOR-interacting protein", "gene_name": "Deptor", "organism": "Rat", "refseq_name": "DEP domain-containing mTOR-interacting protein", "refseq_ac": [ { "id": "NP_001414142", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414142", "type": "external" } ], "gene_names_uniprotkb": "Deptor", "gene_names_refseq": "Depdc6; Deptor; RGD1561030", "protein_names_uniprotkb": "DEP domain-containing mTOR-interacting protein; DEP domain-containing protein 6", "protein_names_refseq": "DEP domain containing 6; DEP domain-containing mTOR-interacting protein", "tax_id": 10116, "disease": "", "pathway": " (rno:314979)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "22673903;25159114;29397070;31176743", "class_list": "", "function": "Low DEPTOR expression is associated with glomerular mesangial cell hypertrophy., [RefSeq, PubMed]; Mechanistically, DEPTOR inhibited both mTOR Complex 1 (mTORC1) and 2 (mTORC2) activities in PA cells. In addition, DEPTOR expression level was increased to suppress mTOR kinase activity via decreasing E3 ubiquitin ligase, betaTrCP1, in response to CAB., [RefSeq, PubMed]; Negative regulator of the mTORC1 and mTORC2 complexes: inhibits the protein kinase activity of MTOR, thereby inactivating both complexes. DEPTOR inhibits mTORC1 and mTORC2 to induce autophagy. In contrast to AKT1S1/PRAS40, only partially inhibits mTORC1 activity., [UniProtKB, UniProtKB]; Results illustrate the presence of DEPTOR in the rat brain and suggest a role for DEPTOR in the hypothalamic regulation of energy balance, which further supports the role of mTOR in energy homeostasis, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0004860 protein kinase inhibitor activity;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0070300 phosphatidic acid binding;GO:0030291 protein serine/threonine kinase inhibitor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005765 lysosomal membrane", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0032007 negative regulation of TOR signaling;GO:0007186 G protein-coupled receptor signaling pathway;GO:0006469 negative regulation of protein kinase activity;GO:0010508 positive regulation of autophagy", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A8I6AIZ7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZX76-1", "uniprot_id": [ { "id": "A0A8I5ZX76_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZX76", "type": "external" } ], "mass": 25115.0, "length": 218, "protein_name": "Eukaryotic translation initiation factor 3 subunit K", "gene_name": "Eif3k", "organism": "Rat", "refseq_name": "eukaryotic translation initiation factor 3 subunit K", "refseq_ac": [ { "id": "NP_001385632", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385632", "type": "external" } ], "gene_names_uniprotkb": "Eif3k; EIF3K; EIF3S12", "gene_names_refseq": "Eif3k; Eif3s12; PLAC-24", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 3 subunit K; Eukaryotic translation initiation factor 3 subunit 12; eIF-3 p25; eIF3k", "protein_names_refseq": "eukaryotic translation initiation factor 3 subunit K; eukaryotic translation initiation factor 3, subunit 12", "tax_id": 10116, "disease": "", "pathway": " (rno:292762); (R-RNO-156827); (R-RNO-72649); (R-RNO-72689); (R-RNO-72695); (R-RNO-72702)", "pathway_count": 6, "publication_count": 3, "publication_id_list": "12006665;16935469;22673903", "class_list": "", "function": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression., [UniProtKB, HAMAP, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Identification of a novel 24-kDa protein (Plac-24) that binds directly to dynein intermediate chain., [RefSeq, PubMed]; These observations suggest that PLAC-24 may play a role in the transport and the stabilisation of newly synthesised 5-HT(7) receptor towards the plasma membrane., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0043022 ribosome binding;GO:0003743 translation initiation factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0016282 eukaryotic 43S preinitiation complex;GO:0033290 eukaryotic 48S preinitiation complex;GO:0005852 eukaryotic translation initiation factor 3 complex;GO:0005829 cytosol", "go_biological_process": "GO:0006446 regulation of translational initiation;GO:0001732 formation of cytoplasmic translation initiation complex;GO:0006413 translational initiation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A8I5ZX76-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AF72-1", "uniprot_id": [ { "id": "A0A8I6AF72_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AF72", "type": "external" } ], "mass": 117883.0, "length": 1050, "protein_name": "MDS1 and EVI1 complex locus", "gene_name": "Mecom", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Mecom", "gene_names_refseq": "", "protein_names_uniprotkb": "MDS1 and EVI1 complex locus", "protein_names_refseq": "", "tax_id": 10116, "disease": "myeloid neoplasm (Disease Ontology:DOID:0070004); otitis media (Disease Ontology:DOID:10754)", "pathway": " (R-RNO-3214841); (R-RNO-8943724)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.367", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.367", "type": "external" }, { "id": "2.1.1.356", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.356", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0042803 protein homodimerization activity;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck;GO:0000118 histone deacetylase complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription;GO:0098727 maintenance of cell number;GO:0001701 in utero embryonic development;GO:0006954 inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I6AF72-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6ATN1-1", "uniprot_id": [ { "id": "A0A8I6ATN1_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6ATN1", "type": "external" } ], "mass": 91147.0, "length": 835, "protein_name": "BCL11 transcription factor A", "gene_name": "Bcl11a", "organism": "Rat", "refseq_name": "B-cell lymphoma/leukemia 11A", "refseq_ac": [ { "id": "NP_001178612", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178612", "type": "external" } ], "gene_names_uniprotkb": "Bcl11a", "gene_names_refseq": "Bcl11a", "protein_names_uniprotkb": "BCL11 transcription factor A", "protein_names_refseq": "B-cell CLL/lymphoma 11A (zinc finger protein); B-cell lymphoma/leukemia 11A; BAF chromatin remodeling complex subunit BCL11A; BCL11A, BAF complex component", "tax_id": 10116, "disease": "specific developmental disorder (Disease Ontology:DOID:0060038); autism spectrum disorder (Disease Ontology:DOID:0060041); sickle cell anemia (Disease Ontology:DOID:10923); beta thalassemia (Disease Ontology:DOID:12241); neurodegenerative disease (Disease Ontology:DOID:1289); lung non-small cell carcinoma (Disease Ontology:DOID:3908); schizophrenia (Disease Ontology:DOID:5419); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (rno:305589); (R-RNO-9933946); (R-RNO-9934037)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "17455301;22673903;37316757", "class_list": "", "function": "Regional and subcellular distributions of Bcl11A/Evi9/CTIP1 in rat brain were investigated by immunostaining and biochemical fractionation, [RefSeq, PubMed]; Transcription Factor BCL11A Regulates Schwann Cell Behavior During Peripheral Nerve Regeneration., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0019901 protein kinase binding;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0003714 transcription corepressor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0016514 SWI/SNF complex;GO:0098794 postsynapse;GO:0016604 nuclear body", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0010628 positive regulation of gene expression;GO:0010629 negative regulation of gene expression;GO:0010976 positive regulation of neuron projection development", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A8I6ATN1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6ATQ4-1", "uniprot_id": [ { "id": "A0A8I6ATQ4_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6ATQ4", "type": "external" } ], "mass": 52949.0, "length": 479, "protein_name": "Paired box 3", "gene_name": "Pax3", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Pax3", "gene_names_refseq": "", "protein_names_uniprotkb": "Paired box 3", "protein_names_refseq": "", "tax_id": 10116, "disease": "neural tube defect (Disease Ontology:DOID:0080074); Waardenburg syndrome type 1 (Disease Ontology:DOID:0110948); Waardenburg syndrome type 3 (Disease 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Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; The regulation of VSMC migration by cofilin is SSH1 dependent and that this mechanism potentially contributes to neointima formation following vascular injury in vivo., [RefSeq, PubMed]; Uppressing endogenous Slingshot with small RNA interference or function-blocking antibody led to a dramatic reduction of AMPA receptor-mediated excitatory postsynaptic currents, [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, 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"0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AVC5-1", "uniprot_id": [ { "id": "A0A8I6AVC5_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AVC5", "type": "external" } ], "mass": 141106.0, "length": 1316, "protein_name": "Latent-transforming growth factor beta-binding protein 3", "gene_name": "Ltbp3", "organism": "Rat", "refseq_name": "latent-transforming growth factor beta-binding protein 3 isoform X2", "refseq_ac": [ { "id": "XP_063131715", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063131715", "type": "external" } ], "gene_names_uniprotkb": "Ltbp3", "gene_names_refseq": "Ltbp3", "protein_names_uniprotkb": "Latent-transforming growth factor beta-binding protein 3", "protein_names_refseq": "latent-transforming growth factor beta-binding protein 3 isoform X2", "tax_id": 10116, "disease": "brachyolmia-amelogenesis imperfecta syndrome (Disease Ontology:DOID:0090143); geleophysic dysplasia 3 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2.1.1.356", "protein_names_refseq": "", "tax_id": 10116, "disease": "diffuse large B-cell lymphoma (Disease Ontology:DOID:0050745); colorectal adenoma (Disease Ontology:DOID:0050860); colorectal adenocarcinoma (Disease Ontology:DOID:0050861); oral squamous cell carcinoma (Disease Ontology:DOID:0050866); syndromic intellectual disability (Disease Ontology:DOID:0050888); myelodysplastic syndrome (Disease Ontology:DOID:0050908); chronic myelomonocytic leukemia (Disease Ontology:DOID:0080188); colorectal carcinoma (Disease Ontology:DOID:0080199); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); prostate cancer (Disease Ontology:DOID:10283); stomach cancer (Disease Ontology:DOID:10534); urinary bladder cancer (Disease Ontology:DOID:11054); leiomyoma (Disease Ontology:DOID:127); lung cancer (Disease Ontology:DOID:1324); Weaver syndrome (Disease Ontology:DOID:14731); pancreatic cancer (Disease Ontology:DOID:1793); colon cancer (Disease Ontology:DOID:219); endometriosis (Disease Ontology:DOID:289); invasive ductal carcinoma (Disease Ontology:DOID:3008); glioblastoma (Disease Ontology:DOID:3068); osteosarcoma (Disease Ontology:DOID:3347); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); cholangiocarcinoma (Disease Ontology:DOID:4947); myelofibrosis (Disease Ontology:DOID:4971); renal Wilms' tumor (Disease Ontology:DOID:5176); congestive heart failure (Disease Ontology:DOID:6000); hepatocellular carcinoma (Disease Ontology:DOID:684); B-cell lymphoma (Disease Ontology:DOID:707); malignant pleural mesothelioma (Disease Ontology:DOID:7474); abdominal aortic aneurysm (Disease Ontology:DOID:7693); chronic myeloid leukemia (Disease Ontology:DOID:8552); acute megakaryocytic leukemia (Disease Ontology:DOID:8761); acute myeloid leukemia (Disease Ontology:DOID:9119); colorectal cancer (Disease Ontology:DOID:9256); nasopharynx carcinoma (Disease Ontology:DOID:9261); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (rno:312299); (R-RNO-212300); (R-RNO-2559580); (R-RNO-3214841); (R-RNO-8943724); (R-RNO-8953750); (R-RNO-9764725); (R-RNO-9909649)", "pathway_count": 8, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 38, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.367", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.367", "type": "external" }, { "id": "2.1.1.356", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.356", "type": "external" }, { "id": "2.1.1.37", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.37", "type": "external" }, { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" } ], "go_molecular_function": "GO:0003682 chromatin binding;GO:0046976 histone H3K27 methyltransferase activity;GO:0140951 histone H3K27 trimethyltransferase activity;GO:0003677 DNA binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0035098 ESC/E(Z) complex;GO:0005654 nucleoplasm;GO:0045202 synapse;GO:0000785 chromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0032259 methylation;GO:0031507 heterochromatin formation;GO:0045605 negative regulation of epidermal cell differentiation;GO:0031509 subtelomeric heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I6AHI4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A1C9-1", "uniprot_id": [ { "id": "A0A8I6A1C9_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A1C9", "type": "external" } ], "mass": 35668.0, "length": 321, "protein_name": "Four and a half LIM domains protein 3", "gene_name": "Fhl3", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Fhl3", "gene_names_refseq": "", "protein_names_uniprotkb": "Four and a half LIM domains protein 3; Skeletal muscle LIM-protein 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:313582)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Recruited by SOX15 to FOXK1 promoters where it acts as a transcriptional coactivator of FOXK1., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003779 actin binding;GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0001725 stress fiber;GO:0030018 Z disc", "go_biological_process": "GO:0030036 actin cytoskeleton organization;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6A1C9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6GJQ1-1", "uniprot_id": [ { "id": "A0A8I6GJQ1_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6GJQ1", "type": "external" } ], "mass": 67965.0, "length": 609, "protein_name": "ADAMTS-like 5", "gene_name": "Adamtsl5", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Adamtsl5", "gene_names_refseq": "", "protein_names_uniprotkb": "ADAMTS-like 5", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:314626); (R-RNO-5173214)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008201 heparin binding;GO:0050436 microfibril binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0031012 extracellular matrix;GO:0001527 microfibril", "go_biological_process": "GO:0030198 extracellular matrix organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I6GJQ1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AQU2-1", "uniprot_id": [ { "id": "A0A8I6AQU2_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AQU2", "type": "external" } ], "mass": 105577.0, "length": 936, "protein_name": "Lysine-specific demethylase 7A", "gene_name": "Kdm7a", "organism": "Rat", "refseq_name": "lysine demethylase 7A", "refseq_ac": [ { "id": "NP_001415848", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001415848", "type": "external" } ], "gene_names_uniprotkb": "Kdm7a", "gene_names_refseq": "Jhdm1d; Kdm7a", "protein_names_uniprotkb": "Lysine-specific demethylase 7A; 1.14.11.65; JmjC domain-containing histone demethylation protein 1D; Lysine-specific demethylase 7; [histone H3]-dimethyl-L-lysine9 demethylase 7A", "protein_names_refseq": "jumonji C domain containing histone demethylase 1; lysine (K)-specific demethylase 7A; lysine demethylase 7A; lysine-specific demethylase 7A", "tax_id": 10116, "disease": "syndromic X-linked intellectual disability (Disease Ontology:DOID:0060309); melanoma (Disease Ontology:DOID:1909)", "pathway": " (R-RNO-3214842)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Histone demethylase required for brain development. Specifically demethylates dimethylated 'Lys-9', 'Lys-27' and 'Lys-36' (H3K9me2, H3K27me2, H3K36me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code. Specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. Demethylates H3K9me2 in absence of H3K4me3. Has activity toward H4K20Me1 only when nucleosome is used as a substrate and when not histone octamer is used as substrate., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.68", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.68", "type": "external" }, { "id": "1.14.11.65", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.65", "type": "external" }, { "id": "1.14.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.-", "type": "external" }, { "id": "1.14.99.66", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.99.66", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0051213 dioxygenase activity;GO:0032452 histone demethylase activity;GO:0035575 histone H4K20 demethylase activity;GO:0051864 histone H3K36 demethylase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006338 chromatin remodeling;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007399 nervous system development;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I6AQU2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6GEK3-1", "uniprot_id": [ { "id": "A0A8I6GEK3_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6GEK3", "type": "external" } ], "mass": 174671.0, "length": 1510, "protein_name": "EF-hand calcium-binding domain-containing protein 6", "gene_name": "Efcab6", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Efcab6", "gene_names_refseq": "", "protein_names_uniprotkb": "EF-hand calcium-binding domain-containing protein 6; DJ-1-binding protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "16641100;22673903", "class_list": "", "function": "Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogation of this complex. Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0036126 sperm flagellum;GO:0160111 axonemal A tubule inner sheath", "go_biological_process": "GO:0030317 flagellated sperm motility", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8I6GEK3-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6APE1-1", "uniprot_id": [ { "id": "A0A8I6APE1_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6APE1", "type": "external" } ], "mass": 123921.0, "length": 1126, "protein_name": "KIAA0319 like", "gene_name": "Kiaa0319l", "organism": "Rat", "refseq_name": "dyslexia-associated protein KIAA0319-like protein homolog isoform X1", "refseq_ac": [ { "id": "XP_063143093", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063143093", "type": "external" } ], "gene_names_uniprotkb": "Kiaa0319l; KIAA0319l; LOC100294508", "gene_names_refseq": "KIAA0319l", "protein_names_uniprotkb": "KIAA0319 like", "protein_names_refseq": "dyslexia-associated protein KIAA0319-like protein homolog isoform X1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "22673903;38843836", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0032588 trans-Golgi network membrane;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0001764 neuron migration;GO:0010996 response to auditory stimulus", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A8I6APE1-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000001000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6A4X3-1", "uniprot_id": [ { "id": "A0A8I6A4X3_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6A4X3", "type": "external" } ], "mass": 45409.0, "length": 430, "protein_name": "Selectin P ligand", "gene_name": "Selplg", "organism": "Rat", "refseq_name": "P-selectin glycoprotein ligand 1 precursor", "refseq_ac": [ { "id": "NP_001382082", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382082", "type": "external" } ], "gene_names_uniprotkb": "Selplg", "gene_names_refseq": "Psgl1; Selplg; Selpl", "protein_names_uniprotkb": "Selectin P ligand", "protein_names_refseq": "P-selectin glycoprotein ligand 1 precursor; P-selectin glycoprotein ligand 1 propeptide; leukocyte cell surface adhesion molecule; selectin, platelet (p-selectin) ligand", "tax_id": 10116, "disease": "carotid artery disease (Disease Ontology:DOID:3407)", "pathway": " (rno:363930); (R-RNO-202733)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "19058306", "class_list": "", "function": "Blockade of P-selectin alone failed to reduced polymorphonuclear leukocyte accumulation in the liver and protect hepatocytes from ischemia-reperfusion injury in the isolated blood-perfused cold-ex vivo rat liver model., [RefSeq, PubMed]", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0044853 plasma membrane raft;GO:0001931 uropod", "go_biological_process": "GO:0050902 leukocyte adhesive activation;GO:0050900 leukocyte migration;GO:0050901 leukocyte tethering or rolling;GO:0071354 cellular response to interleukin-6;GO:1903945 positive regulation of hepatocyte apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I6A4X3-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZM64-1", "uniprot_id": [ { "id": "A0A8I5ZM64_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZM64", "type": "external" } ], "mass": 58279.0, "length": 531, "protein_name": "RCC1 and BTB domain-containing protein 1", "gene_name": "Rcbtb1", "organism": "Rat", "refseq_name": "RCC1 and BTB domain-containing protein 1", "refseq_ac": [ { "id": "NP_001101850", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101850", "type": "external" } ], "gene_names_uniprotkb": "Rcbtb1", "gene_names_refseq": "Rcbtb1", "protein_names_uniprotkb": "RCC1 and BTB domain-containing protein 1; Regulator of chromosome condensation and BTB domain-containing protein 1", "protein_names_refseq": "RCC1 and BTB domain-containing protein 1; regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1", "tax_id": 10116, "disease": "childhood-onset asthma (Disease Ontology:DOID:0080815); allergic disease (Disease Ontology:DOID:1205)", "pathway": " (rno:361050)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in cell cycle regulation by chromatin remodeling., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8I5ZM64-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I5ZXX2-1", "uniprot_id": [ { "id": "A0A8I5ZXX2_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I5ZXX2", "type": "external" } ], "mass": 191181.0, "length": 1762, "protein_name": "Lysine-specific demethylase", "gene_name": "Kdm3b", "organism": "Rat", "refseq_name": "lysine-specific demethylase 3B", "refseq_ac": [ { "id": "NP_001414398", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414398", "type": "external" } ], "gene_names_uniprotkb": "Kdm3b; LOC682469", "gene_names_refseq": "Kdm3b", "protein_names_uniprotkb": "Lysine-specific demethylase; 1.14.11.65", "protein_names_refseq": "lysine (K)-specific demethylase 3B; lysine-specific demethylase 3B-like; lysine-specific demethylase 3B", "tax_id": 10116, "disease": "alcohol use disorder (Disease Ontology:DOID:1574); breast cancer (Disease Ontology:DOID:1612); lung non-small cell carcinoma (Disease Ontology:DOID:3908); colorectal cancer (Disease Ontology:DOID:9256); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (R-RNO-3214842)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.65", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.65", "type": "external" }, { "id": "1.14.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.-", "type": "external" }, { "id": "1.14.99.66", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.99.66", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0140683 histone H3K9me/H3K9me2 demethylase activity;GO:0031490 chromatin DNA binding;GO:0003712 transcription coregulator activity;GO:0032454 histone H3K9 demethylase activity", "go_cellular_component": "GO:0000118 histone deacetylase complex;GO:0005654 nucleoplasm;GO:0000785 chromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0070988 demethylation;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I5ZXX2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AM45-1", "uniprot_id": [ { "id": "A0A8I6AM45_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AM45", "type": "external" } ], "mass": 44685.0, "length": 402, "protein_name": "G protein-coupled receptor 132", "gene_name": "Gpr132", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Gpr132", "gene_names_refseq": "", "protein_names_uniprotkb": "G protein-coupled receptor 132", "protein_names_refseq": "", "tax_id": 10116, "disease": "autoimmune disease (Disease Ontology:DOID:417)", "pathway": " (rno:314480); (R-RNO-373076); (R-RNO-416476)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, 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"gene_names_refseq": "Zfp385b; Zfp533", "protein_names_uniprotkb": "Zinc finger protein 385B; Zinc finger protein 533", "protein_names_refseq": "zinc finger protein 385B isoform a; zinc finger protein 533", "tax_id": 10116, "disease": "", "pathway": " (rno:311137)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May play a role in p53/TP53-mediated apoptosis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, 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"A0A8I5Y545-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8I6AVP7-1", "uniprot_id": [ { "id": "A0A8I6AVP7_RAT", "url": "https://www.uniprot.org/uniprot/A0A8I6AVP7", "type": "external" } ], "mass": 50064.0, "length": 447, "protein_name": "Protein odr-4 homolog", "gene_name": "Odr4", "organism": "Rat", "refseq_name": "protein odr-4 homolog", "refseq_ac": [ { "id": "NP_001414631", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414631", "type": "external" } ], "gene_names_uniprotkb": "Odr4; RGD1307830", "gene_names_refseq": "Odr4; RGD1307830", "protein_names_uniprotkb": "Protein odr-4 homolog", "protein_names_refseq": "protein odr-4 homolog", "tax_id": 10116, "disease": "", "pathway": " (rno:304863)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May play a role in the trafficking of a subset of G-protein 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Contributes to IL18-induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016787 hydrolase activity;GO:0042007 interleukin-18 binding;GO:0042008 interleukin-18 receptor activity", "go_cellular_component": "GO:0016020 membrane;GO:0045092 interleukin-18 receptor complex;GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0120163 negative regulation of cold-induced thermogenesis;GO:0045063 T-helper 1 cell differentiation;GO:0006954 inflammatory response;GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8I6A1C2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true } ]