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KCASH1 protein; Potassium channel tetramerization domain-containing protein 11; RING-type E3 ubiquitin transferase subunit KCTD11", "protein_names_refseq": "BTB/POZ domain-containing protein KCTD11 isoform 2; BTB/POZ domain-containing protein KCTD11; potassium channel tetramerisation domain containing 11", "tax_id": 10116, "disease": "", "pathway": " (rno:363634)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role as a marker and a regulator of neuronal differentiation; Up-regulated by a variety of neurogenic signals, such as retinoic acid, epidermal growth factor/EGF and NGFB/nerve growth factor. Induces apoptosis, growth arrest and the expression of cyclin-dependent kinase inhibitor CDKN1B. Plays a role as a tumor repressor and inhibits cell growth and tumorigenicity of medulloblastoma (MDB). Acts as a probable substrate-specific adapter for a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex towards HDAC1. Functions as antagonist of the Hedgehog pathway on cell proliferation and differentiation by affecting the nuclear transfer of transcription factor GLI1, thus maintaining cerebellar granule cells in undifferentiated state, this effect probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. When knock-down, Hedgehog antagonism is impaired and proliferation of granule cells is sustained. 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RGD1306208", "gene_names_refseq": "", "protein_names_uniprotkb": "LKAAEAR motif containing 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:296483)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZIM8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZIP9-1", "uniprot_id": [ { "id": "D3ZIP9_RAT", "url": "https://www.uniprot.org/uniprot/D3ZIP9", "type": "external" } ], "mass": 69337.0, "length": 592, "protein_name": "Zinc finger protein 68", "gene_name": "Zfp68", "organism": "Rat", "refseq_name": "zinc finger protein 68 isoform 1", "refseq_ac": [ { "id": "NP_001100598", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100598", "type": "external" } ], "gene_names_uniprotkb": "Zfp68", "gene_names_refseq": "Zfp68", "protein_names_uniprotkb": "Zinc finger protein 68", "protein_names_refseq": "zinc finger protein 68 isoform 1", "tax_id": 10116, "disease": "", "pathway": " (rno:304337)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZIP9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZJG5-1", "uniprot_id": [ { "id": "D3ZJG5_RAT", "url": "https://www.uniprot.org/uniprot/D3ZJG5", "type": "external" } ], "mass": 35025.0, "length": 313, "protein_name": "Olfactory receptor family 10 subfamily G member 3C", "gene_name": "Or10g3c", "organism": "Rat", "refseq_name": "olfactory receptor Olr1639", "refseq_ac": [ { "id": "NP_001000833", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000833", "type": "external" } ], "gene_names_uniprotkb": "Or10g3c", "gene_names_refseq": "Olr1639; Or10g3c", "protein_names_uniprotkb": "Olfactory receptor family 10 subfamily G member 3C", "protein_names_refseq": "olfactory receptor 1639; olfactory receptor Olr1639; olfactory receptor gene Olr1639", "tax_id": 10116, "disease": "", "pathway": " (rno:405122)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004790 thioether S-methyltransferase activity;GO:0030748 amine N-methyltransferase activity;GO:0008170 N-methyltransferase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0009308 amine metabolic process;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZNJ5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZNX0-1", "uniprot_id": [ { "id": "D3ZNX0_RAT", "url": "https://www.uniprot.org/uniprot/D3ZNX0", "type": "external" } ], "mass": 88681.0, "length": 816, "protein_name": "BTB/POZ domain-containing protein KCTD3", "gene_name": "Kctd3", "organism": "Rat", "refseq_name": "BTB/POZ domain-containing protein KCTD3", "refseq_ac": [ { "id": "NP_001100669", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100669", "type": "external" } ], "gene_names_uniprotkb": "Kctd3", "gene_names_refseq": "Kctd3; Ren-45", "protein_names_uniprotkb": "BTB/POZ domain-containing protein KCTD3", "protein_names_refseq": "BTB/POZ domain-containing protein KCTD3; potassium channel tetramerisation domain containing 3", "tax_id": 10116, "disease": "", "pathway": " (rno:305055)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Accessory subunit of potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (HCN3) up-regulating its cell-surface expression and current density without affecting its voltage dependence and kinetics., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0051260 protein homooligomerization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZNX0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZP15-1", "uniprot_id": [ { "id": "D3ZP15_RAT", "url": "https://www.uniprot.org/uniprot/D3ZP15", "type": "external" } ], "mass": 22718.0, "length": 201, "protein_name": "small monomeric GTPase", "gene_name": "Rab9b", "organism": "Rat", "refseq_name": "ras-related protein Rab-9B", "refseq_ac": [ { "id": "NP_001102488", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102488", "type": "external" } ], "gene_names_uniprotkb": "Rab9b", "gene_names_refseq": "RGD1562951; Rab9b", "protein_names_uniprotkb": "small monomeric GTPase; 3.6.5.2", "protein_names_refseq": "ras-related protein Rab-9B", "tax_id": 10116, "disease": "", "pathway": " (rno:367915); (R-RNO-6798695); (R-RNO-6811440); (R-RNO-8873719); (R-RNO-8876198); (R-RNO-9706019)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.1", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.4.24.11", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.11", "type": "external" }, { "id": "3.4.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.11.-", "type": "external" }, { "id": "3.4.11.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.11.2", "type": "external" }, { "id": "2.5.1.60", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.60", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "1.2.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.5", "type": "external" }, { "id": "1.2.1.28", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.28", "type": "external" }, { "id": "1.2.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.7", "type": "external" }, { "id": "1.2.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.48", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" } ], "go_molecular_function": "GO:0005525 GTP binding;GO:0042802 identical protein binding;GO:0019003 GDP binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005764 lysosome;GO:0030670 phagocytic vesicle membrane;GO:0005770 late endosome", "go_biological_process": "GO:0015031 protein transport;GO:0006898 receptor-mediated endocytosis;GO:0042147 retrograde transport, endosome to Golgi;GO:0032482 Rab protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZP15-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZPC8-1", "uniprot_id": [ { "id": "D3ZPC8_RAT", "url": "https://www.uniprot.org/uniprot/D3ZPC8", "type": "external" } ], "mass": 31403.0, "length": 278, "protein_name": "X-ray repair cross complementing 2", "gene_name": "Xrcc2", "organism": "Rat", "refseq_name": "DNA repair protein XRCC2", "refseq_ac": [ { "id": "NP_001102685", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102685", "type": "external" } ], "gene_names_uniprotkb": "Xrcc2", "gene_names_refseq": "RGD1564823; Xrcc2", "protein_names_uniprotkb": "X-ray repair cross complementing 2", "protein_names_refseq": "DNA repair protein XRCC2; X-ray repair complementing defective repair in Chinese hamster cells 2; X-ray repair cross complementing protein 2", "tax_id": 10116, "disease": "primary ovarian insufficiency 17 (Disease Ontology:DOID:0080874); Fanconi anemia complementation group U (Disease Ontology:DOID:0111085); spermatogenic failure 50 (Disease Ontology:DOID:0112272); pancreatic cancer (Disease Ontology:DOID:1793)", "pathway": " (rno:499966); (R-RNO-5685942); (R-RNO-5693537); (R-RNO-5693568); (R-RNO-5693579); (R-RNO-5693616)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0000400 four-way junction DNA binding;GO:0140664 ATP-dependent DNA damage sensor activity;GO:0003677 DNA binding", "go_cellular_component": "GO:0005813 centrosome;GO:0005657 replication fork;GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex", "go_biological_process": "GO:2000269 regulation of fibroblast apoptotic process;GO:0000278 mitotic cell cycle;GO:0001701 in utero embryonic development;GO:0006281 DNA repair;GO:0010332 response to gamma radiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZPC8-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZPK4-1", "uniprot_id": [ { "id": "D3ZPK4_RAT", "url": "https://www.uniprot.org/uniprot/D3ZPK4", "type": "external" } ], "mass": 151551.0, "length": 1436, "protein_name": "Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D", "gene_name": "Ssc5d", "organism": "Rat", "refseq_name": "soluble scavenger receptor cysteine-rich domain-containing protein SSC5D precursor", "refseq_ac": [ { "id": "NP_001128017", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001128017", "type": "external" } ], "gene_names_uniprotkb": "Ssc5d", "gene_names_refseq": "RGD1565772; Ssc5d", "protein_names_uniprotkb": "Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D", "protein_names_refseq": "scavenger receptor cysteine rich domain containing (5 domains); scavenger receptor cysteine rich family, 5 domains; soluble scavenger receptor cysteine-rich domain-containing protein SSC5D precursor; soluble scavenger receptor cysteine-rich domain-containing protein SSC5D", "tax_id": 10116, "disease": "", "pathway": " (rno:308341)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Binds to extracellular matrix proteins. Binds to pathogen-associated molecular patterns (PAMPs) present on the cell walls of Gram-positive and Gram-negative bacteria and fungi, behaving as a pattern recognition receptor (PRR). Induces bacterial and fungal aggregation and subsequent inhibition of PAMP-induced cytokine release. Does not possess intrinsic bactericidal activity. 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LOC100911985", "gene_names_refseq": "Olr1238; Or8b43", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1238; olfactory receptor 8B3-like; olfactory receptor Olr1238; olfactory receptor gene Olr1238", "tax_id": 10116, "disease": "", "pathway": " (rno:405387)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZTG0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZTW5-1", "uniprot_id": [ { "id": "D3ZTW5_RAT", "url": "https://www.uniprot.org/uniprot/D3ZTW5", "type": "external" } ], "mass": 52998.0, "length": 473, "protein_name": "Mitochondrial adenyl nucleotide antiporter SLC25A24", "gene_name": "Slc25a54", "organism": "Rat", "refseq_name": "solute carrier family 25, member 54", "refseq_ac": [ { "id": "NP_001103110", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103110", "type": "external" } ], "gene_names_uniprotkb": "Slc25a54; LOC691448", "gene_names_refseq": "Slc25a54", "protein_names_uniprotkb": "Mitochondrial adenyl nucleotide antiporter SLC25A24; Small calcium-binding mitochondrial carrier protein 1; Solute carrier family 25 member 24", "protein_names_refseq": "solute carrier family 25, member 54", "tax_id": 10116, "disease": "", "pathway": " (rno:691448)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Electroneutral antiporter that mediates the transport of adenyl nucleotides through the inner mitochondrial membrane. Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it also acts as a broad specificity adenyl nucleotide antiporter. By regulating the mitochondrial matrix adenyl nucleotide pool, could adapt to changing cellular energetic demands and indirectly regulate adenyl nucleotide-dependent metabolic pathways. In vitro, a low activity is also observed with guanyl and pyrimidine nucleotides. May play a role in protecting cells against oxidative stress-induced cell death, by buffering calcium levels in the mitochondrial matrix through the formation of calcium-phosphate precipitates., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0015297 antiporter activity;GO:0005347 ATP transmembrane transporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005829 cytosol;GO:0005815 microtubule organizing center;GO:0033391 chromatoid body", "go_biological_process": "GO:0015866 ADP transport;GO:0015867 ATP transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZTW5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZTW9-1", "uniprot_id": [ { "id": "D3ZTW9_RAT", "url": "https://www.uniprot.org/uniprot/D3ZTW9", "type": "external" } ], "mass": 41327.0, "length": 368, "protein_name": "Nuclease EXOG, mitochondrial", "gene_name": "Exog", "organism": "Rat", "refseq_name": "nuclease EXOG, mitochondrial precursor", "refseq_ac": [ { "id": "NP_001100336", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100336", "type": "external" } ], "gene_names_uniprotkb": "Exog", "gene_names_refseq": "Endogl1; Exog", "protein_names_uniprotkb": "Nuclease EXOG, mitochondrial; Endonuclease G-like 1", "protein_names_refseq": "endo/exonuclease (5'-3'), endonuclease G-like; endonuclease G-like 1; nuclease EXOG, mitochondrial precursor", "tax_id": 10116, "disease": "", "pathway": " (rno:301062)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "27417117;33515431", "class_list": "", "function": "Endo/exonuclease G-like plays an essential role in cardiomyocyte physiology. Loss of endo/exonuclease G-like results in diminished adaptation to pathological stress. The decline in maximal respiration and reserve capacity is the first sign of mitochondrial dysfunction that determines subsequent cell death., [RefSeq, PubMed]; Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single-stranded DNA and 5'-3' exonuclease activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; PGC-1a Mediated-EXOG, a Specific Repair Enzyme for Mitochondrial DNA, Plays an Essential Role in the Rotenone-Induced Neurotoxicity of PC12 Cells., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0003676 nucleic acid binding;GO:0004521 RNA endonuclease activity;GO:0000014 single-stranded DNA endodeoxyribonuclease activity;GO:0008409 5'-3' exonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005743 mitochondrial inner membrane;GO:0005739 mitochondrion;GO:0032991 protein-containing complex", "go_biological_process": "GO:0006309 apoptotic DNA fragmentation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZTW9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZUL7-1", "uniprot_id": [ { "id": "D3ZUL7_RAT", "url": "https://www.uniprot.org/uniprot/D3ZUL7", "type": "external" } ], "mass": 34263.0, "length": 312, "protein_name": "Olfactory receptor", "gene_name": "Or6ae1", "organism": "Rat", "refseq_name": "olfactory receptor Olr286", "refseq_ac": [ { "id": "NP_001000554", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000554", "type": "external" } ], "gene_names_uniprotkb": "Or6ae1", "gene_names_refseq": "Olr286; Or6ae1", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 286; olfactory receptor Olr286; olfactory receptor gene Olr286", "tax_id": 10116, "disease": "", "pathway": " (rno:365384)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZUL7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZUP5-1", "uniprot_id": [ { "id": "D3ZUP5_RAT", "url": "https://www.uniprot.org/uniprot/D3ZUP5", "type": "external" } ], "mass": 8761.0, "length": 75, "protein_name": "Protein BRICK1", "gene_name": "Brk1", "organism": "Rat", "refseq_name": "protein BRICK1", "refseq_ac": [ { "id": "NP_001182405", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182405", "type": "external" } ], "gene_names_uniprotkb": "Brk1", "gene_names_refseq": "Brk1", "protein_names_uniprotkb": "Protein BRICK1", "protein_names_refseq": "BRICK1, SCAR/WAVE actin-nucleating complex subunit; probable protein BRICK1; protein BRICK1", "tax_id": 10116, "disease": "", "pathway": " (rno:679934); (R-RNO-2029482); (R-RNO-4420097); (R-RNO-5663213); (R-RNO-9013149); (R-RNO-9013404); (R-RNO-9013423)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0044877 protein-containing complex binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0030027 lamellipodium;GO:0031209 SCAR complex", "go_biological_process": "GO:0008064 regulation of actin polymerization or depolymerization;GO:0001701 in utero embryonic development;GO:0007015 actin filament organization;GO:0008284 positive regulation of cell population proliferation;GO:0030036 actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZUP5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZUR6-1", "uniprot_id": [ { "id": "D3ZUR6_RAT", "url": "https://www.uniprot.org/uniprot/D3ZUR6", "type": "external" } ], "mass": 78745.0, "length": 696, "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "Usp51", "organism": "Rat", "refseq_name": "ubiquitin carboxyl-terminal hydrolase 51", "refseq_ac": [ { "id": "NP_001101722", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101722", "type": "external" } ], "gene_names_uniprotkb": "Usp51", "gene_names_refseq": "RGD1562211; 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thrombospondin type-1 domain-containing protein 1; thrombospondin, type I, domain 1; thrombospondin, type I, domain containing 1", "tax_id": 10116, "disease": "hereditary lymphedema (Disease Ontology:DOID:0050580); intracranial berry aneurysm 12 (Disease Ontology:DOID:0080975)", "pathway": " (rno:364630); (R-RNO-5173214)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "19143766;22673903", "class_list": "", "function": "C5b-9 can promote proliferation of GMCs and secretion of fibronectin as well as synthesis of thrombospondin-1 and transforming growth factor-beta(1), [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0050840 extracellular matrix binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005768 endosome;GO:0005829 cytosol;GO:0005925 focal adhesion;GO:0009986 cell surface", "go_biological_process": "GO:0048041 focal adhesion assembly;GO:0002244 hematopoietic progenitor cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZW62-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZWC6-1", "uniprot_id": [ { "id": "D3ZWC6_RAT", "url": "https://www.uniprot.org/uniprot/D3ZWC6", "type": "external" } ], "mass": 58292.0, "length": 539, "protein_name": "Beta-1-syntrophin", "gene_name": "Sntb1", "organism": "Rat", "refseq_name": "beta-1-syntrophin", "refseq_ac": [ { "id": "NP_001124014", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001124014", "type": "external" } ], "gene_names_uniprotkb": "Sntb1", "gene_names_refseq": "Sntb1", "protein_names_uniprotkb": "Beta-1-syntrophin; 59 kDa dystrophin-associated protein A1 basic component 1; Syntrophin-2", "protein_names_refseq": "beta-1-syntrophin; syntrophin, basic 1", "tax_id": 10116, "disease": "Duchenne muscular dystrophy (Disease Ontology:DOID:11723); muscular dystrophy (Disease Ontology:DOID:9884)", "pathway": " (rno:299940); (R-RNO-9913351)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. 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RGD1560242", "gene_names_refseq": "Cfap95; RGD1560242", "protein_names_uniprotkb": "Cilia and flagella associated protein 95", "protein_names_refseq": "cilia- and flagella-associated protein 95 isoform 1; uncharacterized protein C9orf135 homolog", "tax_id": 10116, "disease": "", "pathway": " (rno:499334)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005737 cytoplasm;GO:0036126 sperm flagellum;GO:0005879 axonemal microtubule;GO:0160111 axonemal A tubule inner sheath", "go_biological_process": "GO:0030317 flagellated sperm motility", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZWG8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZYQ3-1", "uniprot_id": [ { "id": "D3ZYQ3_RAT", "url": "https://www.uniprot.org/uniprot/D3ZYQ3", "type": "external" } ], "mass": 80250.0, "length": 708, "protein_name": "Tumor necrosis factor alpha-induced protein 2", "gene_name": "Tnfaip2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Tnfaip2", "gene_names_refseq": "", "protein_names_uniprotkb": "Tumor necrosis factor alpha-induced protein 2; 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LOC690206", "gene_names_refseq": "1700013G24Rikl", "protein_names_uniprotkb": "RIKEN cDNA 1700013G24 gene like", "protein_names_refseq": "uncharacterized protein LOC690206", "tax_id": 10116, "disease": "", "pathway": " (rno:690206)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZYU7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZZ44-1", "uniprot_id": [ { "id": "D3ZZ44_RAT", "url": "https://www.uniprot.org/uniprot/D3ZZ44", "type": "external" } ], "mass": 90871.0, "length": 829, "protein_name": "Extracellular leucine-rich repeat and fibronectin type III domain containing 1", "gene_name": "Elfn1", "organism": "Rat", "refseq_name": "protein ELFN1 precursor", "refseq_ac": [ { "id": "NP_001099383", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099383", "type": "external" } ], "gene_names_uniprotkb": "Elfn1; 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C7h12orf73; LOC691921", "gene_names_refseq": "C7h12orf73; Uqcc6", "protein_names_uniprotkb": "Ubiquinol-cytochrome c reductase complex assembly factor 6", "protein_names_refseq": "protein BRAWNIN; uncharacterized protein C12orf73 homolog", "tax_id": 10116, "disease": "", "pathway": " (rno:691921)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0033617 mitochondrial respiratory chain complex IV assembly;GO:0034551 mitochondrial respiratory chain complex III assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZZG3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZZJ5-1", "uniprot_id": [ { "id": "D3ZZJ5_RAT", "url": "https://www.uniprot.org/uniprot/D3ZZJ5", "type": "external" } ], "mass": 21958.0, "length": 197, "protein_name": "Lysozyme g-like protein", "gene_name": "Lyg1", "organism": "Rat", "refseq_name": "lysozyme g-like protein 1 precursor", "refseq_ac": [ { "id": "NP_001092308", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092308", "type": "external" } ], "gene_names_uniprotkb": "Lyg1", "gene_names_refseq": "Lyg1; RGD1560332", "protein_names_uniprotkb": "Lysozyme g-like protein; 3.2.1.-", "protein_names_refseq": "lysozyme G-like 1; lysozyme g-like protein 1 precursor; lysozyme g-like protein 1-like; lysozyme g-like protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:503254)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "29393594", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003796 lysozyme activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0050830 defense response to Gram-positive bacterium;GO:0009253 peptidoglycan catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZZJ5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZZX1-1", "uniprot_id": [ { "id": "I5P1_RAT", "url": "https://www.uniprot.org/uniprot/D3ZZX1", "type": "external" } ], "mass": 47622.0, "length": 412, "protein_name": "Inositol polyphosphate-5-phosphatase A", "gene_name": "Inpp5a", "organism": "Rat", "refseq_name": "inositol polyphosphate-5-phosphatase A", "refseq_ac": [ { "id": "NP_001102393", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102393", "type": "external" } ], "gene_names_uniprotkb": "Inpp5a", "gene_names_refseq": "Inpp5a", "protein_names_uniprotkb": "Inositol polyphosphate-5-phosphatase A; 3.1.3.56; 5PTase; Type I inositol 1,4,5-trisphosphate 5-phosphatase", "protein_names_refseq": "5PTase; inositol polyphosphate-5-phosphatase A; type I inositol 1,4,5-trisphosphate 5-phosphatase-like; type I inositol 1,4,5-trisphosphate 5-phosphatase", "tax_id": 10116, "disease": "", "pathway": " (rno:365382); (R-RNO-1855183)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "8626616", "class_list": "", "function": "Phosphatase that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate, and inositol 1,3,4,5-tetrasphosphate to inositol 1,3,4-trisphosphate (PubMed:8626616). Plays a crucial role in the survival of cerebellar Purkinje cells (By similarity)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.86", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.86", "type": "external" }, { "id": "3.1.3.56", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.56", "type": "external" }, { "id": "3.1.3.36", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.36", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" }, { "id": "3.1.3.95", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.95", "type": "external" } ], "go_molecular_function": "GO:0042731 PH domain binding;GO:0004445 inositol-polyphosphate 5-phosphatase activity;GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity;GO:0052659 inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030425 dendrite", "go_biological_process": "GO:0050849 negative regulation of calcium-mediated signaling;GO:0046856 phosphatidylinositol dephosphorylation;GO:1900737 negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0043647 inositol phosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZZX1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A0A6-1", "uniprot_id": [ { "id": "D4A0A6_RAT", "url": "https://www.uniprot.org/uniprot/D4A0A6", "type": "external" } ], "mass": 37094.0, "length": 326, "protein_name": "Olfactory receptor", "gene_name": "Or4k6", "organism": "Rat", "refseq_name": "olfactory receptor Olr1609", "refseq_ac": [ { "id": "NP_001000973", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000973", "type": "external" } ], "gene_names_uniprotkb": "Or4k6", "gene_names_refseq": "Olr1609; Or4k6", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1609; olfactory receptor Olr1609; olfactory receptor gene Olr1609", "tax_id": 10116, "disease": "leukocyte adhesion deficiency 3 (Disease Ontology:DOID:0110912); platelet-type bleeding disorder 18 (Disease Ontology:DOID:0111051)", "pathway": " (rno:405328)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "29393594", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A0A6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A265-1", "uniprot_id": [ { "id": "D4A265_RAT", "url": "https://www.uniprot.org/uniprot/D4A265", "type": "external" } ], "mass": 15060.0, "length": 135, "protein_name": "Nescient helix loop helix 2", "gene_name": "Nhlh2", "organism": "Rat", "refseq_name": "helix-loop-helix protein 2", "refseq_ac": [ { "id": "NP_001099927", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099927", "type": "external" } ], "gene_names_uniprotkb": "Nhlh2", "gene_names_refseq": "Nhlh2", "protein_names_uniprotkb": "Nescient helix loop helix 2", "protein_names_refseq": "helix-loop-helix protein 2", "tax_id": 10116, "disease": "hypogonadotropic hypogonadism (Disease Ontology:DOID:0090070)", "pathway": " (rno:295327)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0000785 chromatin", "go_biological_process": "GO:0060179 male mating behavior;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A265-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A3A7-1", "uniprot_id": [ { "id": "D4A3A7_RAT", "url": "https://www.uniprot.org/uniprot/D4A3A7", "type": "external" } ], "mass": 57065.0, "length": 508, "protein_name": "Bestrophin", "gene_name": "Best2", "organism": "Rat", "refseq_name": "bestrophin-2", "refseq_ac": [ { "id": "NP_001383034", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383034", "type": "external" } ], "gene_names_uniprotkb": "Best2", "gene_names_refseq": "Best2; Vmd2l1", "protein_names_uniprotkb": "Bestrophin", "protein_names_refseq": "bestrophin-2; vitelliform macular dystrophy 2-like protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:364973); (R-RNO-2672351)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "21498420", "class_list": "", "function": "Forms calcium-sensitive chloride channels. Permeable to bicarbonate., [UniProtKB, UniProtKB]; MRNA levels for bestrophin-1 and -2 were also significantly reduced by bestrophin-3 down-regulation, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, 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"WAP four-disulfide core domain 16", "gene_name": "Wfdc16", "organism": "Rat", "refseq_name": "WAP four-disulfide core domain 16 precursor", "refseq_ac": [ { "id": "NP_001240607", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001240607", "type": "external" } ], "gene_names_uniprotkb": "Wfdc16", "gene_names_refseq": "Wfdc16", "protein_names_uniprotkb": "WAP four-disulfide core domain 16", "protein_names_refseq": "WAP four-disulfide core domain 16 precursor; WAP four-disulfide core domain protein 16", "tax_id": 10116, "disease": "", "pathway": " (rno:685201)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, 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humoral response;GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A3B9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A3D9-1", "uniprot_id": [ { "id": "D4A3D9_RAT", "url": "https://www.uniprot.org/uniprot/D4A3D9", "type": "external" } ], "mass": 56604.0, "length": 499, "protein_name": "Serine/threonine-protein kinase 32C", "gene_name": "Stk32c", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Stk32c", "gene_names_refseq": "", "protein_names_uniprotkb": "Serine/threonine-protein kinase 32C; 2.7.11.1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, 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"secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.34", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" }, { "id": "2.7.11.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.19", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.11.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.4", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.4.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.18", "type": "external" }, { "id": "3.1.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.24.-", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "", "go_biological_process": "GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A3D9-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A4U3-1", "uniprot_id": [ { "id": "D4A4U3_RAT", "url": "https://www.uniprot.org/uniprot/D4A4U3", "type": "external" } ], "mass": 27387.0, "length": 236, "protein_name": "Magnesium-dependent phosphatase 1", "gene_name": "Mdp1", "organism": "Rat", "refseq_name": "magnesium-dependent phosphatase 1 isoform 1", "refseq_ac": [ { "id": "NP_001388557", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001388557", "type": "external" } ], "gene_names_uniprotkb": "Mdp1", "gene_names_refseq": "Mdp-1; Mdp1; RGD1311147", "protein_names_uniprotkb": "Magnesium-dependent phosphatase 1; 3.1.3.48", "protein_names_refseq": "magnesium-dependent phosphatase 1 isoform 1", "tax_id": 10116, "disease": "", "pathway": "", 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} ], "mass": 42858.0, "length": 379, "protein_name": "Polyadenylate-binding protein 5", "gene_name": "Pabpc5", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Pabpc5; LOC100360473", "gene_names_refseq": "", "protein_names_uniprotkb": "Polyadenylate-binding protein 5", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:688518)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Binds the poly(A) tail of mRNA. 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May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "7.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.9.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.9.1.1", "type": "external" }, { "id": "6.1.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.12", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0019843 rRNA binding;GO:0003724 RNA helicase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0042645 mitochondrial nucleoid;GO:0035770 ribonucleoprotein granule", "go_biological_process": "GO:1902775 mitochondrial large ribosomal subunit assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A7Q5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A8D2-1", "uniprot_id": [ { "id": "D4A8D2_RAT", "url": "https://www.uniprot.org/uniprot/D4A8D2", "type": "external" } ], "mass": 33999.0, "length": 312, "protein_name": "Retinol dehydrogenase", "gene_name": "Rdh8", "organism": "Rat", "refseq_name": "retinol dehydrogenase 8", "refseq_ac": [ { "id": "NP_001162065", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162065", "type": "external" } ], "gene_names_uniprotkb": "Rdh8", "gene_names_refseq": "Rdh8", "protein_names_uniprotkb": "Retinol dehydrogenase; 1.1.1.300", "protein_names_refseq": "retinol dehydrogenase 8 (all-trans); retinol dehydrogenase 8", "tax_id": 10116, "disease": "", "pathway": " (rno:690953)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinal to all-trans-retinol. May play a role in the regeneration of visual pigment at high light intensity., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.1.300", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.300", "type": "external" }, { "id": "1.1.1.184", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.184", "type": "external" }, { "id": "1.1.1.122", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.122", "type": "external" }, { "id": "1.1.1.30", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.30", "type": "external" }, { "id": "1.1.1.104", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.104", "type": "external" }, { "id": "1.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.-", "type": "external" }, { "id": "1.1.1.62", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.62", "type": "external" }, { "id": "1.1.1.239", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.239", "type": "external" }, { "id": "1.1.1.105", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.105", "type": "external" }, { "id": "1.1.1.209", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.209", "type": "external" }, { "id": "1.1.1.53", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.53", "type": "external" }, { "id": "1.1.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.35", "type": "external" }, { "id": "1.1.1.178", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.178", "type": "external" }, { "id": "1.1.1.159", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.159", "type": "external" }, { "id": "1.1.1.21", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.21", "type": "external" }, { "id": "1.1.1.372", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.372", "type": "external" }, { "id": "1.1.1.54", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.54", "type": "external" }, { "id": "1.1.1.n12", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.n12", "type": "external" }, { "id": "1.1.1.330", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.330", "type": "external" } ], "go_molecular_function": "GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity;GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity;GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity", "go_cellular_component": "GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0042572 retinol metabolic process;GO:0007601 visual perception;GO:0006703 estrogen biosynthetic process;GO:0061370 testosterone biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A8D2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A8W4-1", "uniprot_id": [ { "id": "D4A8W4_RAT", "url": "https://www.uniprot.org/uniprot/D4A8W4", "type": "external" } ], "mass": 11049.0, "length": 101, "protein_name": "Prostate and testis expressed 14 like 2", "gene_name": "Pate14l2", "organism": "Rat", "refseq_name": "prostate and testis expressed 14 like 2 precursor", "refseq_ac": [ { "id": "NP_001247413", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001247413", "type": "external" } ], "gene_names_uniprotkb": "Pate14l2; LOC100360049", "gene_names_refseq": "Pate14l2", "protein_names_uniprotkb": "Prostate and testis expressed 14 like 2", "protein_names_refseq": "Secreted seminal-vesicle Ly-6 protein 1-like; prostate and testis expressed 14 like 2 precursor; prostate and testis expressed protein P; rCG64165-like", "tax_id": 10116, "disease": "", "pathway": " (rno:100360049)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "H9MZ09", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A8W4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AA42-1", "uniprot_id": [ { "id": "D4AA42_RAT", "url": "https://www.uniprot.org/uniprot/D4AA42", "type": "external" } ], "mass": 40137.0, "length": 354, "protein_name": "G protein subunit alpha transducin 2", "gene_name": "Gnat2", "organism": "Rat", "refseq_name": "guanine nucleotide-binding protein G(t) subunit alpha-2", "refseq_ac": [ { "id": "NP_001102420", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102420", "type": "external" } ], "gene_names_uniprotkb": "Gnat2", "gene_names_refseq": "Gnat2", "protein_names_uniprotkb": "G protein subunit alpha transducin 2", "protein_names_refseq": "guanine nucleotide binding protein (G protein), alpha transducing 2; guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2; guanine nucleotide binding protein, alpha transducing 2; guanine nucleotide-binding protein G(t) subunit alpha-2", "tax_id": 10116, "disease": "cone-rod dystrophy (Disease Ontology:DOID:0050572); achromatopsia 4 (Disease Ontology:DOID:0110010); color blindness (Disease Ontology:DOID:13399); achromatopsia (Disease Ontology:DOID:13911); McCune Albright syndrome (Disease Ontology:DOID:1858)", "pathway": " (rno:365901); (R-RNO-4086398); (R-RNO-418594)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0001664 G protein-coupled receptor binding;GO:0031683 G-protein beta/gamma-subunit complex binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0045202 synapse;GO:0001917 photoreceptor inner segment;GO:0001750 photoreceptor outer segment;GO:0005834 heterotrimeric G-protein complex", "go_biological_process": "GO:0009583 detection of light stimulus;GO:0048877 homeostasis of number of retina cells;GO:0007186 G protein-coupled receptor signaling pathway;GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0000902 cell morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4AA42-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AAK3-1", "uniprot_id": [ { "id": "D4AAK3_RAT", "url": "https://www.uniprot.org/uniprot/D4AAK3", "type": "external" } ], "mass": 62460.0, "length": 581, "protein_name": "Cysteine and serine rich nuclear protein 1", "gene_name": "Csrnp1", "organism": "Rat", "refseq_name": "cysteine/serine-rich nuclear protein 1", "refseq_ac": [ { "id": "NP_001102256", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102256", "type": "external" } ], "gene_names_uniprotkb": "Csrnp1", "gene_names_refseq": "Axud1; Csrnp1", "protein_names_uniprotkb": "Cysteine and serine rich nuclear protein 1", "protein_names_refseq": "AXIN1 up-regulated 1; cysteine/serine-rich nuclear protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:363165)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "28830684;29393594", "class_list": "", "function": "Axud1 mediated stress-induced cardiomyocytes apoptosis through activating Wnt/beta-catenin signaling pathway., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0043565 sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:0006915 apoptotic process;GO:0009791 post-embryonic development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D4AAK3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AC19-1", "uniprot_id": [ { "id": "D4AC19_RAT", "url": "https://www.uniprot.org/uniprot/D4AC19", "type": "external" } ], "mass": 26188.0, "length": 238, "protein_name": "Distal-less homeobox 4", "gene_name": "Dlx4", "organism": "Rat", "refseq_name": "homeobox protein DLX-4", "refseq_ac": [ { "id": "NP_001100510", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100510", "type": "external" } ], "gene_names_uniprotkb": "Dlx4", "gene_names_refseq": "Dlx4", "protein_names_uniprotkb": "Distal-less homeobox 4", "protein_names_refseq": "homeobox protein DLX-4", "tax_id": 10116, "disease": "orofacial cleft 15 (Disease Ontology:DOID:0080408)", "pathway": " (rno:303469)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, 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negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0048706 embryonic skeletal system development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4AC19-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ACD2-1", "uniprot_id": [ { "id": "D4ACD2_RAT", "url": "https://www.uniprot.org/uniprot/D4ACD2", "type": "external" } ], "mass": 81543.0, "length": 739, "protein_name": "BTB domain and CNC homolog 1", "gene_name": "Bach1", "organism": "Rat", "refseq_name": "transcription regulator protein BACH1", "refseq_ac": [ { "id": "NP_001100583", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100583", "type": "external" } ], "gene_names_uniprotkb": "Bach1; LOC100911490", "gene_names_refseq": "Bach1", "protein_names_uniprotkb": "BTB domain and CNC homolog 1", 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Publication Status: Online-Only, [RefSeq, PubMed]; Renal denervation improves mitochondrial oxidative stress and cardiac hypertrophy through inactivating SP1/BACH1-PACS2 signaling., [RefSeq, PubMed]; The Bach1/HO-1 pathway regulates oxidative stress and contributes to ferroptosis in doxorubicin-induced cardiomyopathy in H9c2 cells and mice., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0090575 RNA polymerase II transcription regulator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006281 DNA repair;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "D4ACD2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ACE4-1", "uniprot_id": [ { "id": "D4ACE4_RAT", "url": "https://www.uniprot.org/uniprot/D4ACE4", "type": "external" } ], "mass": 34114.0, "length": 328, "protein_name": "Homeobox protein Hox-D1", "gene_name": "Hoxd1", "organism": "Rat", "refseq_name": "homeobox protein Hox-D1", "refseq_ac": [ { "id": "NP_001099354", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099354", "type": "external" } ], "gene_names_uniprotkb": "Hoxd1", "gene_names_refseq": "Hoxd1", "protein_names_uniprotkb": "Homeobox protein Hox-D1", "protein_names_refseq": "homeobox protein Hox-D1", "tax_id": 10116, "disease": "", "pathway": " (rno:288151)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, 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"protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ACF2-1", "uniprot_id": [ { "id": "D4ACF2_RAT", "url": "https://www.uniprot.org/uniprot/D4ACF2", "type": "external" } ], "mass": 55101.0, "length": 480, "protein_name": "E3 ubiquitin-protein ligase TRIM21", "gene_name": "Trim21", "organism": "Rat", "refseq_name": "E3 ubiquitin-protein ligase TRIM21 isoform X1", "refseq_ac": [ { "id": "XP_006229946", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006229946", "type": "external" } ], "gene_names_uniprotkb": "Trim21", "gene_names_refseq": "Trim21", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase TRIM21; 2.3.2.27; 52 kDa Ro protein; 52 kDa ribonucleoprotein autoantigen Ro/SS-A; Ro(SS-A); Sjoegren syndrome type A antigen; Tripartite motif-containing protein 21", "protein_names_refseq": "E3 ubiquitin-protein ligase TRIM21 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-3134975); (R-RNO-9755511); (R-RNO-983168)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "2.3.2.32", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.32", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "2.3.2.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.24", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0003713 transcription coactivator activity;GO:0003723 RNA binding;GO:0008270 zinc ion binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0031410 cytoplasmic vesicle;GO:0019005 SCF ubiquitin ligase complex", "go_biological_process": "GO:0032897 negative regulation of viral transcription;GO:0044790 suppression of viral release by host;GO:0045087 innate immune response;GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction;GO:0046598 positive regulation of viral entry into host cell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4ACF2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ADG2-1", "uniprot_id": [ { "id": "D4ADG2_RAT", "url": "https://www.uniprot.org/uniprot/D4ADG2", "type": "external" } ], "mass": 38674.0, "length": 358, "protein_name": "Iron-sulfur cluster assembly factor IBA57, mitochondrial", "gene_name": "Iba57", "organism": "Rat", "refseq_name": "putative transferase CAF17, mitochondrial", "refseq_ac": [ { "id": "NP_001102297", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102297", "type": "external" } ], "gene_names_uniprotkb": "Iba57", "gene_names_refseq": "Iba57; RGD1306000", "protein_names_uniprotkb": "Iron-sulfur cluster assembly factor IBA57, mitochondrial; Iron-sulfur cluster assembly factor homolog", "protein_names_refseq": "IBA57 homolog, iron-sulfur cluster assembly; IBA57 iron-sulfur cluster assembly; IBA57, iron-sulfur cluster assembly homolog; putative transferase CAF17 homolog, mitochondrial; putative transferase CAF17, mitochondrial", "tax_id": 10116, "disease": "multiple mitochondrial dysfunctions syndrome 3 (Disease Ontology:DOID:0080135); hereditary spastic paraplegia 74 (Disease Ontology:DOID:0110819)", "pathway": " (rno:363611)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Mitochondrial protein involved in the maturation of mitochondrial [4Fe-4S]-proteins in the late stage of the iron-sulfur cluster assembly pathway. Operates in cooperation with ISCA2 in the maturation of [4Fe-4S] proteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:1990229 iron-sulfur cluster assembly complex", "go_biological_process": "GO:0006783 heme biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4ADG2-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AEC7-1", "uniprot_id": [ { "id": "D4AEC7_RAT", "url": "https://www.uniprot.org/uniprot/D4AEC7", "type": "external" } ], "mass": 88953.0, "length": 801, "protein_name": "Protein-lysine N-methyltransferase SMYD4", "gene_name": "Smyd4", "organism": "Rat", "refseq_name": "SET and MYND domain-containing protein 4", "refseq_ac": [ { "id": "NP_001099280", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099280", "type": "external" } ], "gene_names_uniprotkb": "Smyd4", "gene_names_refseq": "Smyd4", "protein_names_uniprotkb": "Protein-lysine N-methyltransferase SMYD4; SET and MYND domain-containing protein 4", "protein_names_refseq": "SET and MYND domain-containing protein 4", "tax_id": 10116, "disease": "congenital heart disease (Disease Ontology:DOID:1682)", "pathway": " (rno:287525)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Protein-lysine N-methyltransferase. Monomethylates PRMT5, modulating its transcriptional activity. May also act as a histone methyltransferase. Plays a critical role in cardiac development. Acts as a key epigenetic regulator of gene expression during cardiac development via its dual activities as a methyltransferase and negative regulator of HDAC1., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.361", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.361", "type": "external" }, { "id": "2.1.1.359", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.359", "type": "external" }, { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" }, { "id": "2.1.1.355", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.355", "type": "external" }, { "id": "2.1.1.354", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.354", "type": "external" }, { "id": "2.1.1.362", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.362", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042826 histone deacetylase binding;GO:0016279 protein-lysine N-methyltransferase activity;GO:0008168 methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0007507 heart development;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4AEC7-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AEF4-1", "uniprot_id": [ { "id": "D4AEF4_RAT", "url": "https://www.uniprot.org/uniprot/D4AEF4", "type": "external" } ], "mass": 94168.0, "length": 875, "protein_name": "Kelch-like family member 29", "gene_name": "Klhl29", "organism": "Rat", "refseq_name": "kelch-like protein 29", "refseq_ac": [ { "id": "NP_001100183", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100183", "type": "external" } ], "gene_names_uniprotkb": "Klhl29", "gene_names_refseq": "Kbtbd9; Klhl29", "protein_names_uniprotkb": "Kelch-like family member 29", "protein_names_refseq": "kelch repeat and BTB (POZ) domain containing 9; kelch-like 29; kelch-like protein 29", "tax_id": 10116, "disease": "", "pathway": " (rno:298867)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:1990756 ubiquitin-like ligase-substrate adaptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0031463 Cul3-RING ubiquitin ligase complex", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4AEF4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AEN1-1", "uniprot_id": [ { "id": "D4AEN1_RAT", "url": "https://www.uniprot.org/uniprot/D4AEN1", "type": "external" } ], "mass": 30773.0, "length": 263, "protein_name": "Receptor (chemosensory) transporter protein 1", "gene_name": "Rtp1", "organism": "Rat", "refseq_name": "receptor-transporting protein 1", "refseq_ac": [ { "id": "NP_001099340", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099340", "type": "external" } ], "gene_names_uniprotkb": "Rtp1", "gene_names_refseq": "RGD1560980; Rtp1", "protein_names_uniprotkb": "Receptor (chemosensory) transporter protein 1", "protein_names_refseq": "receptor transporter protein 1; receptor-transporting protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:288006)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0031849 olfactory receptor binding", "go_cellular_component": "GO:0009986 cell surface;GO:0016020 membrane", "go_biological_process": "GO:0006612 protein targeting to membrane;GO:0051205 protein insertion into membrane;GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4AEN1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E9PSJ3-1", "uniprot_id": [ { "id": "E9PSJ3_RAT", "url": "https://www.uniprot.org/uniprot/E9PSJ3", "type": "external" } ], "mass": 139682.0, "length": 1231, "protein_name": "Kinesin family member 4A", "gene_name": "Kif4a", "organism": "Rat", "refseq_name": "chromosome-associated kinesin KIF4A", "refseq_ac": [ { "id": "NP_001387859", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001387859", "type": "external" } ], "gene_names_uniprotkb": "Kif4a", "gene_names_refseq": "Kif4a; Kif4", "protein_names_uniprotkb": "Kinesin family member 4A", "protein_names_refseq": "chromosome-associated kinesin KIF4A; kinesin family member 4; kinesin heavy chain member 4", "tax_id": 10116, "disease": "non-syndromic X-linked intellectual disability 100 (Disease Ontology:DOID:0112040); epilepsy (Disease Ontology:DOID:1826)", "pathway": " (rno:84393); (R-RNO-2132295); (R-RNO-437239); (R-RNO-6811434); (R-RNO-983189)", "pathway_count": 5, "publication_count": 3, "publication_id_list": "19158085;22673903;25260485", "class_list": "", "function": "KIF4 is involved in the anterograde trafficking of ribosomal constituents to axons, [RefSeq, PubMed]; Knockdown of KIF4A expression with shRNA reduced the level of integrin beta1 in axons of developing neurons., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0046872 metal ion binding;GO:0003777 microtubule motor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005874 microtubule;GO:0005875 microtubule associated complex;GO:0030496 midbody", "go_biological_process": "GO:0000281 mitotic cytokinesis;GO:0007018 microtubule-based movement;GO:0007052 mitotic spindle organization;GO:0051256 mitotic spindle midzone assembly;GO:0051231 spindle elongation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "E9PSJ3-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LU78-1", "uniprot_id": [ { "id": "F1LU78_RAT", "url": "https://www.uniprot.org/uniprot/F1LU78", "type": "external" } ], "mass": 127584.0, "length": 1135, "protein_name": "Sentrin-specific protease 6", "gene_name": "Senp6", "organism": "Rat", "refseq_name": "sentrin-specific protease 6", "refseq_ac": [ { "id": "NP_001100312", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100312", "type": "external" } ], "gene_names_uniprotkb": "Senp6", "gene_names_refseq": "Senp6", "protein_names_uniprotkb": "Sentrin-specific protease 6; SUMO-1-specific protease 1; Sentrin/SUMO-specific protease SENP6", "protein_names_refseq": "SUMO/sentrin specific peptidase 6; SUMO/sentrin specific protease 6; SUMO1/sentrin specific peptidase 6; Sumo1/sentrin/SMT3 specific peptidase 6; sentrin-specific protease 6", "tax_id": 10116, "disease": "", "pathway": " (rno:300860)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "22673903;29393594;31781182", "class_list": "", "function": "Our data suggest that ethanol exposure during adolescence induces the microglia-mediated neuroinflammation via TLR4 activation, and SENP6 plays an essential role in dampening NF-kappaB activation and neuroinflammation. Publication Status: Online-Only, [RefSeq, PubMed]; Protease that deconjugates SUMO1, SUMO2 and SUMO3 from targeted proteins. Processes preferentially poly-SUMO2 and poly-SUMO3 chains, but does not efficiently process SUMO1, SUMO2 and SUMO3 precursors. Deconjugates SUMO1 from RXRA, leading to transcriptional activation. Involved in chromosome alignment and spindle assembly, by regulating the kinetochore CENPH-CENPI-CENPK complex. Desumoylates PML and CENPI, protecting them from degradation by the ubiquitin ligase RNF4, which targets polysumoylated proteins for proteasomal degradation. Also desumoylates RPA1, thus preventing recruitment of RAD51 to the DNA damage foci to initiate DNA repair through homologous recombination., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0070139 SUMO-specific endopeptidase activity;GO:0008234 cysteine-type peptidase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0099523 presynaptic cytosol;GO:0099524 postsynaptic cytosol", "go_biological_process": "GO:0070646 protein modification by small protein removal;GO:0006508 proteolysis;GO:0090169 regulation of spindle assembly;GO:0090234 regulation of kinetochore assembly;GO:0016926 protein desumoylation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "F1LU78-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LV28-1", "uniprot_id": [ { "id": "F1LV28_RAT", "url": "https://www.uniprot.org/uniprot/F1LV28", "type": "external" } ], "mass": 23225.0, "length": 196, "protein_name": "Cilia and flagella associated protein 107", "gene_name": "Cfap107", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Cfap107; LOC691162", "gene_names_refseq": "", "protein_names_uniprotkb": "Cilia and flagella associated protein 107", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0036126 sperm flagellum;GO:0005879 axonemal microtubule;GO:0160111 axonemal A tubule inner sheath", "go_biological_process": "GO:0030317 flagellated sperm motility", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LV28-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LVX1-1", "uniprot_id": [ { "id": "F1LVX1_RAT", "url": "https://www.uniprot.org/uniprot/F1LVX1", "type": "external" } ], "mass": 65360.0, "length": 565, "protein_name": "DnaJ homolog subfamily C member 1", "gene_name": "Dnajc1", "organism": "Rat", "refseq_name": "dnaJ homolog subfamily C member 1", "refseq_ac": [ { "id": "NP_001387766", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001387766", "type": "external" } ], "gene_names_uniprotkb": "Dnajc1", "gene_names_refseq": "Dnajc1", "protein_names_uniprotkb": "DnaJ homolog subfamily C member 1; DnaJ protein homolog MTJ1", "protein_names_refseq": "DnaJ (Hsp40) homolog, subfamily C, member 1-like; dnaJ homolog subfamily C member 1", "tax_id": 10116, "disease": "", "pathway": " (rno:100360412)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "May modulate protein synthesis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0051087 protein-folding chaperone binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0031965 nuclear membrane;GO:0005789 endoplasmic reticulum membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0006417 regulation of translation;GO:0006457 protein folding;GO:0050708 regulation of protein secretion", "synthesized_glycan_count": 0, 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RNA-binding motif protein 18", "protein_names_refseq": "probable RNA-binding protein 18", "tax_id": 10116, "disease": "", "pathway": " (rno:311902)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "G3V6X2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "G3V6X6-1", "uniprot_id": [ { "id": "G3V6X6_RAT", "url": "https://www.uniprot.org/uniprot/G3V6X6", "type": "external" } ], "mass": 20070.0, "length": 179, "protein_name": "Interleukin 22", "gene_name": "Il22", "organism": "Rat", "refseq_name": "interleukin-22 precursor", "refseq_ac": [ { "id": "NP_001178917", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178917", "type": "external" } ], "gene_names_uniprotkb": "Il22", "gene_names_refseq": "If2b1; 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Publication Status: Online-Only, [RefSeq, PubMed]; The that IL-22 plays a protective role in this process via the down-regulation of uncoupling protein-2 (UCP-2)., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005125 cytokine activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0043235 receptor complex;GO:0140368 decoy receptor complex", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0050728 negative regulation of inflammatory response;GO:0051384 response to glucocorticoid;GO:0072593 reactive oxygen species metabolic process;GO:0042509 regulation of tyrosine phosphorylation of STAT protein", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "G3V6X6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "G3V817-1", "uniprot_id": [ { "id": "G3V817_RAT", "url": "https://www.uniprot.org/uniprot/G3V817", "type": "external" } ], "mass": 83092.0, "length": 732, "protein_name": "DNA repair protein Ku80", "gene_name": "Xrcc5", "organism": "Rat", "refseq_name": "X-ray repair cross-complementing protein 5", "refseq_ac": [ { "id": "NP_803154", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_803154", "type": "external" } ], "gene_names_uniprotkb": "Xrcc5", "gene_names_refseq": "Ku80; Kup80; Xrcc5", "protein_names_uniprotkb": "DNA repair protein Ku80; 4.2.99.18; 5.6.2.4", "protein_names_refseq": "Ku autoantigen, 80kD); X-ray repair complementing defective repair in Chinese hamster cells 5; X-ray repair cross complementation (double-strand-break rejoining; X-ray repair cross-complementing protein 5", "tax_id": 10116, "disease": "COVID-19 (Disease Ontology:DOID:0080600); neurodegeneration with brain iron accumulation (Disease Ontology:DOID:0110734); hemochromatosis 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{ "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": 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"3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "3.4.25.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.25.1", "type": "external" }, { "id": "1.11.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.24", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003684 damaged DNA binding;GO:0042162 telomeric DNA binding;GO:0003678 DNA helicase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0043564 Ku70:Ku80 complex;GO:0070419 nonhomologous end joining complex;GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006310 DNA recombination;GO:0000723 telomere maintenance;GO:0006303 double-strand break repair via nonhomologous end joining;GO:1904430 negative regulation of t-circle formation;GO:0008283 cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "G3V817-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "G3V8D0-1", "uniprot_id": [ { "id": "G3V8D0_RAT", "url": "https://www.uniprot.org/uniprot/G3V8D0", "type": "external" } ], "mass": 43902.0, "length": 380, "protein_name": "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3", "gene_name": "St8sia3", "organism": "Rat", "refseq_name": "sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase", "refseq_ac": [ { "id": "NP_037161", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_037161", "type": "external" } ], "gene_names_uniprotkb": "St8sia3", "gene_names_refseq": "Siat8c; St8sia3", "protein_names_uniprotkb": "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3", "protein_names_refseq": "GT3-synthase; ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 3; Sialyltransferase 8 (GT3 alpha 2,8-sialyltransferase) C; Sialyltransferase 8 (GT3 alpha 28-sialyltransferase) C; sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase; sialyltransferase 8 C", "tax_id": 10116, "disease": "inflammatory bowel disease (Disease Ontology:DOID:0050589); autosomal dominant hypophosphatemic rickets (Disease Ontology:DOID:0050948); uremia (Disease Ontology:DOID:4676); chronic kidney disease (Disease Ontology:DOID:784)", "pathway": " (rno:25547); (R-RNO-4085001); (R-RNO-975577)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "38843836", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity;GO:0042802 identical protein binding;GO:0008373 sialyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0009101 glycoprotein biosynthetic process;GO:0009311 oligosaccharide metabolic process;GO:0009100 glycoprotein metabolic process;GO:0006491 N-glycan processing;GO:0097503 sialylation", "synthesized_glycan_count": 21, "hit_score": 0.4, "record_id": "G3V8D0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "G3V8K2-1", "uniprot_id": [ { "id": "G3V8K2_RAT", "url": "https://www.uniprot.org/uniprot/G3V8K2", "type": "external" } ], "mass": 8305.0, "length": 75, "protein_name": "Guanine nucleotide-binding protein subunit gamma", "gene_name": "Gng3", "organism": "Rat", "refseq_name": "guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3", "refseq_ac": [ { "id": "NP_446110", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_446110", "type": "external" } ], "gene_names_uniprotkb": "Gng3", "gene_names_refseq": "Gng3; Hg3d", "protein_names_uniprotkb": "Guanine nucleotide-binding protein subunit gamma", "protein_names_refseq": "guanine nucleotide binding protein (G protein), gamma 3; guanine nucleotide binding protein, gamma 3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3; heterotrimeric guanine nucleotide-binding protein 3d", "tax_id": 10116, "disease": "obesity (Disease Ontology:DOID:9970)", "pathway": " (rno:114117); (R-RNO-1296041); (R-RNO-202040); (R-RNO-381676); (R-RNO-392170); (R-RNO-392451); (R-RNO-400042); (R-RNO-4086398); (R-RNO-416476); (R-RNO-418594); (R-RNO-418597); (R-RNO-420092); (R-RNO-428930); (R-RNO-432040); (R-RNO-456926); (R-RNO-8964616); (R-RNO-9856530); (R-RNO-997272)", "pathway_count": 18, "publication_count": 2, "publication_id_list": "18613791;22673903", "class_list": "", "function": "Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction., [UniProtKB, UniProtKB]; Myocyte gamma(3) gene expression is regulated by myocyte-specific M-CAT and MEF-1 elements., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031681 G-protein beta-subunit binding", "go_cellular_component": "GO:0014069 postsynaptic density;GO:0030425 dendrite;GO:0045202 synapse;GO:0044297 cell body;GO:0005834 heterotrimeric G-protein complex", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007204 positive regulation of cytosolic calcium ion concentration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "G3V8K2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "G3V8M6-1", "uniprot_id": [ { "id": "G3V8M6_RAT", "url": "https://www.uniprot.org/uniprot/G3V8M6", "type": "external" } ], "mass": 29571.0, "length": 255, "protein_name": "Folate receptor alpha", "gene_name": "Folr1", "organism": "Rat", "refseq_name": "folate receptor alpha precursor", "refseq_ac": [ { "id": "NP_598211", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_598211", "type": "external" } ], "gene_names_uniprotkb": "Folr1", "gene_names_refseq": "Fbp1; Folr1", "protein_names_uniprotkb": "Folate receptor alpha", "protein_names_refseq": "folate binding protein 1; folate receptor 1 (adult); folate receptor alpha precursor", "tax_id": 10116, "disease": "cerebral folate receptor alpha deficiency (Disease Ontology:DOID:0050719)", "pathway": " (rno:171049); (R-RNO-204005); (R-RNO-5694530); (R-RNO-6807878)", "pathway_count": 4, "publication_count": 4, "publication_id_list": "26667416;27011008;30113208;36675153", "class_list": "", "function": "A Paternal Methylation Error in the Congenital Hydrocephalic Texas (H-Tx) Rat Is Partially Rescued with Natural Folate Supplements. Publication Status: Online-Only, [RefSeq, PubMed]; Folr1 plays an important role in folate and sulfur amino acid levels and affects glucose and lipid metabolism in the rat., [RefSeq, PubMed]; Inherited variation in the expression of Folr1 in the kidney influences the development of the metabolic syndrome, [RefSeq, PubMed]; These observations have implications in the pathology of FRa-autoantibodies associated with neural tube defect pregnancy, preterm birth and neurodevelopmental disorders including autism Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005542 folic acid binding;GO:0061714 folic acid receptor activity;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane;GO:0009897 external side of plasma membrane;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0017015 regulation of transforming growth factor beta receptor signaling pathway;GO:0046654 tetrahydrofolate biosynthetic process;GO:0035036 sperm-egg recognition;GO:0007155 cell adhesion;GO:0007342 fusion of sperm to egg plasma membrane involved in single fertilization", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "G3V8M6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "G3V8N8-1", "uniprot_id": [ { "id": "G3V8N8_RAT", "url": "https://www.uniprot.org/uniprot/G3V8N8", "type": "external" } ], "mass": 34903.0, "length": 304, "protein_name": "Probable RNA polymerase II nuclear localization protein SLC7A6OS", "gene_name": "Slc7a6os", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Slc7a6os", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable RNA polymerase II nuclear localization protein SLC7A6OS", "protein_names_refseq": "", "tax_id": 10116, "disease": "progressive myoclonus epilepsy (Disease Ontology:DOID:891)", "pathway": " (rno:246187)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Directs RNA polymerase II nuclear import., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0015031 protein transport;GO:0032502 developmental process;GO:0002244 hematopoietic progenitor cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "G3V8N8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "G3V8R3-1", "uniprot_id": [ { "id": "G3V8R3_RAT", "url": "https://www.uniprot.org/uniprot/G3V8R3", "type": "external" } ], "mass": 16078.0, "length": 142, "protein_name": "Hemoglobin subunit zeta", "gene_name": "Hbz", "organism": "Rat", "refseq_name": "hemoglobin subunit zeta", "refseq_ac": [ { "id": "NP_001166316", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001166316", "type": "external" } ], "gene_names_uniprotkb": "Hbz", "gene_names_refseq": "Glne1; Hbz; RGD1307486", "protein_names_uniprotkb": "Hemoglobin subunit zeta; Hemoglobin zeta chain; Zeta-globin", "protein_names_refseq": "globin e1; hemoglobin subunit zeta; hemoglobin, zeta; zeta-globin", "tax_id": 10116, "disease": "", "pathway": " (rno:287168)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "The zeta chain is an alpha-type chain of mammalian embryonic hemoglobin., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0019825 oxygen binding;GO:0005344 oxygen carrier activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005833 hemoglobin complex;GO:0031838 haptoglobin-hemoglobin complex", "go_biological_process": "GO:0048821 erythrocyte development;GO:0015671 oxygen transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "G3V8R3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "G3V8Z6-1", "uniprot_id": [ { "id": "G3V8Z6_RAT", "url": "https://www.uniprot.org/uniprot/G3V8Z6", "type": "external" } ], "mass": 84006.0, "length": 736, "protein_name": "Krev interaction trapped protein 1", "gene_name": "Krit1", "organism": "Rat", "refseq_name": "krev interaction trapped protein 1", "refseq_ac": [ { "id": "NP_001102088", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102088", "type": "external" } ], "gene_names_uniprotkb": "Krit1", "gene_names_refseq": "Krit1; RGD1305929", "protein_names_uniprotkb": "Krev interaction trapped protein 1", "protein_names_refseq": "krev interaction trapped protein 1", "tax_id": 10116, "disease": "cerebral cavernous malformation (Disease Ontology:DOID:0060669); cerebral cavernous malformation 1 (Disease Ontology:DOID:0080491)", "pathway": " (rno:362317)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, 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Exhibits reductive 3-beta-hydroxysteroid dehydrogenase activity toward 5-beta-androstanes, 5-beta-pregnanes, 4-pregnenes and bile acids. May contribute to the metabolism of adrenal-derived androgen precursors. Reduces 11-keto-4-androstene-3,17-dione (11KA4) and 11-keto-5alpha-androstane-3,17-dione (11K-Adione) into potent androgens 11-ketotestosterone (11KT) and 11-ketodihydrotestosterone (11KDHT), respectively. May also reduce endogenous and exogenous alpha-dicarbonyl compounds and xenobiotic alicyclic ketones., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.1.270", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.270", "type": "external" }, { "id": "1.1.1.62", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.62", "type": "external" }, { "id": "1.1.1.239", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.239", "type": "external" }, { "id": "1.1.1.105", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.105", "type": "external" }, { "id": "1.1.1.209", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.209", "type": "external" }, { "id": "1.1.1.53", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.53", "type": "external" }, { "id": "1.1.1.64", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.64", "type": "external" }, { "id": "1.1.1.145", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.145", "type": "external" }, { "id": "5.3.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.1", "type": "external" }, { "id": "1.1.1.210", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.210", "type": "external" }, { "id": "1.3.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.3", "type": "external" }, { "id": "1.1.1.330", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.330", "type": "external" } ], "go_molecular_function": "GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity;GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity;GO:0000253 3-beta-hydroxysteroid 3-dehydrogenase (NADP+) activity;GO:0016491 oxidoreductase activity", "go_cellular_component": "", "go_biological_process": "GO:0006694 steroid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "G3V978-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "G3V9L1-1", "uniprot_id": [ { "id": "G3V9L1_RAT", "url": "https://www.uniprot.org/uniprot/G3V9L1", "type": "external" } ], "mass": 124407.0, "length": 1122, "protein_name": "Testis expressed 2", "gene_name": "Tex2", "organism": "Rat", "refseq_name": "testis-expressed protein 2", "refseq_ac": [ { "id": "NP_001094024", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094024", "type": "external" } ], "gene_names_uniprotkb": "Tex2", "gene_names_refseq": "Tex2", "protein_names_uniprotkb": "Testis expressed 2", "protein_names_refseq": "testis expressed gene 2; 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LOC100912291", "gene_names_refseq": "4930444P10Rik; C5h8orf89", "protein_names_uniprotkb": "Similar to human chromosome 8 open reading frame 89", "protein_names_refseq": "putative uncharacterized protein C8orf89 homolog", "tax_id": 10116, "disease": "", "pathway": " (rno:100912291)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R8B2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R9R7-1", "uniprot_id": [ { "id": "M0R9R7_RAT", "url": "https://www.uniprot.org/uniprot/M0R9R7", "type": "external" } ], "mass": 35381.0, "length": 313, "protein_name": "Olfactory receptor", "gene_name": "Or8c18", "organism": "Rat", "refseq_name": "olfactory receptor Olr1226", "refseq_ac": [ { "id": "NP_001000442", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000442", "type": "external" } ], "gene_names_uniprotkb": "Or8c18", "gene_names_refseq": "Olr1226; 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II-specific;GO:1990837 sequence-specific double-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0RDI4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0RDM1-1", "uniprot_id": [ { "id": "M0RDM1_RAT", "url": "https://www.uniprot.org/uniprot/M0RDM1", "type": "external" } ], "mass": 113338.0, "length": 1070, "protein_name": "Sal-like protein 4", "gene_name": "Sall4", "organism": "Rat", "refseq_name": "sal-like protein 4", "refseq_ac": [ { "id": "NP_001414424", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414424", "type": "external" } ], "gene_names_uniprotkb": "Sall4; LOC686412", "gene_names_refseq": "Sall4", "protein_names_uniprotkb": "Sal-like protein 4; Zinc finger protein SALL4", "protein_names_refseq": "sal-like 4; sal-like protein 4", "tax_id": 10116, "disease": "Holt-Oram syndrome (Disease Ontology:DOID:0060468); Duane-radial ray syndrome (Disease Ontology:DOID:0060747); IVIC syndrome (Disease Ontology:DOID:0111381); otitis media (Disease Ontology:DOID:10754); Duane retraction syndrome (Disease Ontology:DOID:12557); ventricular septal defect (Disease Ontology:DOID:1657); endodermal sinus tumor (Disease Ontology:DOID:1911); ovarian germ cell cancer (Disease Ontology:DOID:2156); carcinoma (Disease Ontology:DOID:305); hepatoblastoma (Disease Ontology:DOID:687)", "pathway": " (rno:686412); (R-RNO-8943724)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, 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"external" } ], "mass": 67954.0, "length": 629, "protein_name": "Chaperonin containing TCP1 subunit 8 like 2", "gene_name": "Cct8l2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Cct8l2; Cct8l1; LOC102553845", "gene_names_refseq": "", "protein_names_uniprotkb": "Chaperonin containing TCP1 subunit 8 like 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:499967)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 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"https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.9.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.9.1.1", "type": "external" }, { "id": "6.1.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.12", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0051082 unfolded protein binding;GO:0016887 ATP hydrolysis activity;GO:0140662 ATP-dependent protein folding chaperone", "go_cellular_component": "GO:0005832 chaperonin-containing T-complex", "go_biological_process": "GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q3B7U6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q4KLZ0-1", "uniprot_id": [ { "id": "Q4KLZ0_RAT", "url": "https://www.uniprot.org/uniprot/Q4KLZ0", "type": "external" } ], "mass": 57013.0, "length": 512, "protein_name": "Pantetheinase", "gene_name": "Vnn1", "organism": "Rat", "refseq_name": "pantetheinase precursor", "refseq_ac": [ { "id": "NP_001020794", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020794", "type": "external" } ], "gene_names_uniprotkb": "Vnn1", "gene_names_refseq": "Tiff66; Vnn1", "protein_names_uniprotkb": 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Publication Status: Online-Only, [RefSeq, PubMed]; Pharmacological inhibition of vanin activity attenuates development of transplant vasculopathy. This was accompanied by reduced macrophage infiltration and increased glutathione-synthesizing capacity., [RefSeq, PubMed]; Proteomic-based study identifies vanin-1 as a marker of kidney damage in a rat model of type 1 diabetic nephropathy., [RefSeq, PubMed]; Urinary vanin-1 is a potentially sensitive biomarker for ameliorating renal tubular damage in salt-sensitive hypertension. Publication Status: Online-Only, [RefSeq, PubMed]; Urinary vanin-1 may serve as a candidate biomarker of renal tubular injury due to hydronephrosis. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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Rab38 influiences proteinuria independently of glomerular damage., [RefSeq, PubMed]; In an experimental diabetes model, Rab38 knockout rats showed higher urinary albumin concentrations and reduced amounts of megalin and cubilin at the proximal tubule cell surface compared to control rats., [RefSeq, PubMed]; Rab38 affects urinary protein excretion via effects in the proximal tubule., [RefSeq, PubMed]; Results indicate that Rab38 is expressed non-ubiquitously in specific tissues & regulates early vesicle transport relating to the endoplasmic reticulum; suggested that Rab38 abnormality may cause multiple organ diseases as well as oculocutaneous albinism, [RefSeq, PubMed]; The small GTPases Rab are key regulators in vesicle trafficking., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A6I5Z5", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.1", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" } ], "go_molecular_function": "GO:0035651 AP-3 adaptor complex binding;GO:0036461 BLOC-2 complex binding;GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0030742 GTP-dependent protein binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005769 early endosome;GO:0016020 membrane;GO:0048471 perinuclear region of cytoplasm;GO:0005764 lysosome", "go_biological_process": "GO:1903232 melanosome assembly;GO:0090383 phagosome acidification;GO:0006886 intracellular protein transport;GO:2001247 positive regulation of phosphatidylcholine biosynthetic process;GO:0060155 platelet dense granule organization", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q63483-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6DGG9-1", "uniprot_id": [ { "id": "CAMLG_RAT", "url": "https://www.uniprot.org/uniprot/Q6DGG9", "type": "external" } ], "mass": 32790.0, "length": 295, "protein_name": "Guided entry of tail-anchored proteins factor CAMLG", "gene_name": "Camlg", "organism": "Rat", "refseq_name": "guided entry of tail-anchored proteins factor CAMLG isoform 1", "refseq_ac": [ { "id": "NP_001385655", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385655", "type": "external" } ], "gene_names_uniprotkb": "Camlg; Caml; Get2", "gene_names_refseq": "Camlg; Caml", "protein_names_uniprotkb": "Guided entry of tail-anchored proteins factor CAMLG; Calcium signal-modulating cyclophilin ligand", "protein_names_refseq": "calcium signal-modulating cyclophilin ligand; guided entry of tail-anchored proteins factor CAMLG isoform 1; guided entry of tail-anchored proteins factor CAMLG", "tax_id": 10116, "disease": "congenital disorder of glycosylation type IIz (Disease Ontology:DOID:0051053); myeloid leukemia (Disease Ontology:DOID:8692)", "pathway": " (rno:81715)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "11762198;23041287;29967478", "class_list": "", "function": "CAML role in the hepatocyte proliferation.TMUB1 regulates hepatocyte proliferation by interacting with CAML and further interferes with the binding of CAML to cyclophilin B. Publication Status: Online-Only, [RefSeq, PubMed]; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum (PubMed:23041287). Together with GET1/WRB, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol (PubMed:23041287). Required for the stability of GET1 (By similarity). Stimulates calcium signaling in T cells through its involvement in elevation of intracellular calcium (By similarity). Essential for the survival of peripheral follicular B cells (By similarity)., [UniProtKB, UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F7FMD6;Q9ERK1", "ec_number_list": [], "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding;GO:0050839 cell adhesion molecule binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0043529 GET complex", "go_biological_process": "GO:0050821 protein stabilization;GO:0016192 vesicle-mediated transport;GO:0031397 negative regulation of protein ubiquitination;GO:0001782 B cell homeostasis;GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q6DGG9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6IE17-1", "uniprot_id": [ { "id": "Q6IE17_RAT", "url": "https://www.uniprot.org/uniprot/Q6IE17", "type": "external" } ], "mass": 11610.0, "length": 103, "protein_name": "Stefin A2-like 1", "gene_name": "Stfa2l1", "organism": "Rat", "refseq_name": "stefin-3", "refseq_ac": [ { "id": "NP_001004129", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004129", "type": "external" } ], "gene_names_uniprotkb": "Stfa2l1", "gene_names_refseq": "Stfa2l1; Stfa2", "protein_names_uniprotkb": "Stefin A2-like 1", "protein_names_refseq": "stefin A2; stefin-3", "tax_id": 10116, "disease": "peeling skin syndrome 4 (Disease Ontology:DOID:0070523)", "pathway": " (rno:408214)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "This is an intracellular thiol proteinase inhibitor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3ZEL6", "ec_number_list": [], "go_molecular_function": "GO:0004869 cysteine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q6IE17-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6IMK2-1", "uniprot_id": [ { "id": "Q6IMK2_RAT", "url": "https://www.uniprot.org/uniprot/Q6IMK2", "type": "external" } ], "mass": 47873.0, "length": 457, "protein_name": "Transcription factor Sp7", "gene_name": "Sp7", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Sp7", "gene_names_refseq": "", "protein_names_uniprotkb": "Transcription factor Sp7; Zinc finger protein osterix", "protein_names_refseq": "", "tax_id": 10116, "disease": "osteogenesis imperfecta type 12 (Disease Ontology:DOID:0110348); aortic valve stenosis (Disease Ontology:DOID:1712)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcriptional activator essential for osteoblast differentiation. Binds to SP1 and EKLF consensus sequences and to other G/C-rich sequences., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0017151 DEAD/H-box RNA helicase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0071344 diphosphate metabolic process;GO:0006357 regulation of transcription by RNA polymerase II;GO:0060218 hematopoietic stem cell differentiation;GO:0001649 osteoblast differentiation;GO:0071529 cementum mineralization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q6IMK2-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q71B06-1", "uniprot_id": [ { "id": "Q71B06_RAT", "url": "https://www.uniprot.org/uniprot/Q71B06", "type": "external" } ], "mass": 19473.0, "length": 173, "protein_name": "CKLF-like MARVEL transmembrane domain containing 8", "gene_name": "Cmtm8", "organism": "Rat", "refseq_name": "CKLF-like MARVEL transmembrane domain-containing protein 8", "refseq_ac": [ { "id": "NP_942049", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_942049", "type": "external" } ], "gene_names_uniprotkb": "Cmtm8", "gene_names_refseq": "Cklfsf8; Cmtm8", "protein_names_uniprotkb": "CKLF-like MARVEL transmembrane domain containing 8", "protein_names_refseq": "CKLF-like MARVEL transmembrane domain-containing protein 8; chemokine-like factor super family 8; chemokine-like related protein 8", "tax_id": 10116, "disease": "", "pathway": " (rno:301045)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, 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E5", "protein_names_uniprotkb": "Rho guanine nucleotide exchange factor 15", "protein_names_refseq": "Rho guanine nucleotide exchange factor (GEF) 15; ephexin-5; rho guanine nucleotide exchange factor 15", "tax_id": 10116, "disease": "brain small vessel disease 5 with osteoporosis (Disease Ontology:DOID:0061235)", "pathway": " (rno:287418); (R-RNO-193648); (R-RNO-416482); (R-RNO-8980692); (R-RNO-9013148); (R-RNO-9013149)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0098794 postsynapse;GO:0005737 cytoplasm", "go_biological_process": "GO:0032956 regulation of actin cytoskeleton organization;GO:0035025 positive regulation of Rho protein signal transduction;GO:0061299 retina vasculature morphogenesis in camera-type eye;GO:2000297 negative regulation of synapse maturation;GO:0150052 regulation of postsynapse assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JTU0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JTV4-1", "uniprot_id": [ { "id": "A0A0G2JTV4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JTV4", "type": "external" } ], "mass": 35027.0, "length": 312, "protein_name": "Olfactory receptor", "gene_name": "Or7g32", "organism": "Rat", "refseq_name": "olfactory receptor Olr1148", "refseq_ac": [ { "id": "NP_001000875", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000875", "type": "external" } ], "gene_names_uniprotkb": "Or7g32", "gene_names_refseq": "Olr1148; Or7g32", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1148; olfactory receptor Olr1148; olfactory receptor gene Olr1148", "tax_id": 10116, "disease": "", "pathway": " (rno:405173)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JTV4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JTW4-1", "uniprot_id": [ { "id": "A0A0G2JTW4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JTW4", "type": "external" } ], "mass": 36717.0, "length": 325, "protein_name": "N-lysine methyltransferase KMT5A", "gene_name": "AABR07010705.1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "AABR07010705.1", "gene_names_refseq": "", "protein_names_uniprotkb": "N-lysine methyltransferase KMT5A; 2.1.1.361; H4-K20-HMTase KMT5A; Histone-lysine N-methyltransferase KMT5A; Lysine-specific methylase 5A; PR/SET domain-containing protein 07; SET domain-containing protein 8", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher-order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones. Mediates monomethylation of p53/TP53 at 'Lys-382', leading to repress p53/TP53-target genes. Plays a negative role in TGF-beta response regulation and a positive role in cell migration., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.361", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.361", "type": "external" }, { "id": "2.1.1.359", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.359", "type": "external" }, { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" }, { "id": "2.1.1.362", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.362", "type": "external" }, { "id": "2.1.1.355", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.355", "type": "external" }, { "id": "2.1.1.354", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.354", "type": "external" } ], "go_molecular_function": "GO:0042799 histone H4K20 methyltransferase activity;GO:0140944 histone H4K20 monomethyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005700 polytene chromosome", "go_biological_process": "GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0051301 cell division;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JTW4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JU37-1", "uniprot_id": [ { "id": "A0A0G2JU37_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JU37", "type": "external" } ], "mass": 6049.0, "length": 56, "protein_name": "Keratin associated protein 20-22", "gene_name": "LOC134481131", "organism": "Rat", "refseq_name": "keratin-associated protein 20-2-like", "refseq_ac": [ { "id": "XP_063127032", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063127032", "type": "external" } ], "gene_names_uniprotkb": "LOC134481131", "gene_names_refseq": "LOC134481131", "protein_names_uniprotkb": "Keratin associated protein 20-22", "protein_names_refseq": "keratin-associated protein 20-2-like", "tax_id": 10116, "disease": "", "pathway": " (rno:134481131); 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LOC120098596", "gene_names_refseq": "", "protein_names_uniprotkb": "Gamma-aminobutyric acid receptor-associated protein-like 2; GABA(A) receptor-associated protein-like 2; Golgi-associated ATPase enhancer of 16 kDa", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:120098596)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1. Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding;GO:0008429 phosphatidylethanolamine binding", "go_cellular_component": "GO:0000421 autophagosome membrane", "go_biological_process": "GO:0097352 autophagosome maturation;GO:0000045 autophagosome assembly;GO:0000423 mitophagy;GO:0006995 cellular response to nitrogen starvation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JU55-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JUG7-1", "uniprot_id": [ { "id": "IQEC1_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JUG7", "type": "external" } ], "mass": 108080.0, "length": 962, "protein_name": "IQ motif and SEC7 domain-containing protein 1", "gene_name": "Iqsec1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Iqsec1; Brag2", "gene_names_refseq": "", "protein_names_uniprotkb": "IQ motif and SEC7 domain-containing protein 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "intellectual developmental disorder with short stature and behavioral abnormalities (Disease Ontology:DOID:0111674); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910)", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "20547133;22673903;38843836", "class_list": "", "function": "Guanine nucleotide exchange factor for ARF1 and ARF6. Guanine nucleotide exchange factor activity is enhanced by lipid binding. Accelerates GTP binding by ARFs of all three classes. Guanine nucleotide exchange protein for ARF6, mediating internalization of beta-1 integrin. Involved in neuronal development (By similarity). In neurons, plays a role in the control of vesicle formation by endocytoc cargo. Upon long term depression, interacts with GRIA2 and mediates the activation of ARF6 to internalize synaptic AMPAR receptors (PubMed:20547133)., [UniProtKB, UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0008289 lipid binding;GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0008021 synaptic vesicle;GO:0099092 postsynaptic density, intracellular component", "go_biological_process": "GO:0051549 positive regulation of keratinocyte migration;GO:0060996 dendritic spine development;GO:0051965 positive regulation of synapse assembly;GO:0016192 vesicle-mediated transport;GO:0032012 regulation of ARF protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0G2JUG7-1", "record_type": "protein", "filter_code": "0000000.0000110.010000.000000000000001000.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JV24-1", "uniprot_id": [ { "id": "A0A0G2JV24_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JV24", "type": "external" } ], "mass": 129806.0, "length": 1171, "protein_name": "Thrombospondin-1", "gene_name": "Thbs1", "organism": "Rat", "refseq_name": "thrombospondin-1 isoform 2 precursor", "refseq_ac": [ { "id": "NP_001385869", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385869", "type": "external" } ], "gene_names_uniprotkb": "Thbs1", "gene_names_refseq": "TSP-1; Thbs1; Tsp1", "protein_names_uniprotkb": "Thrombospondin-1; Glycoprotein G", "protein_names_refseq": "thrombospondin-1 isoform 2 precursor", "tax_id": 10116, "disease": "COVID-19 (Disease Ontology:DOID:0080600); prostate cancer (Disease Ontology:DOID:10283); primary open angle glaucoma (Disease Ontology:DOID:1070); urinary bladder cancer (Disease Ontology:DOID:11054); heart disease (Disease Ontology:DOID:114); Sjogren's syndrome (Disease Ontology:DOID:12894); pancreatic cancer (Disease Ontology:DOID:1793); pancreatic ductal carcinoma (Disease Ontology:DOID:3587); cholangiocarcinoma (Disease Ontology:DOID:4947); myocardial infarction (Disease Ontology:DOID:5844); diabetic retinopathy (Disease Ontology:DOID:8947); colorectal cancer (Disease Ontology:DOID:9256); obesity (Disease Ontology:DOID:9970)", "pathway": " (R-RNO-114608); (R-RNO-186797); (R-RNO-216083); (R-RNO-5173214)", "pathway_count": 4, "publication_count": 5, "publication_id_list": "36920202;37573658;38108523;38237742;38439091", "class_list": "", "function": "Exosomes derived from menstrual blood stromal cells ameliorated premature ovarian insufficiency and granulosa cell apoptosis by regulating SMAD3/AKT/MDM2/P53 pathway via delivery of thrombospondin-1., [RefSeq, PubMed]; RNF7 Induces Skeletal Muscle Cell Apoptosis and Arrests Cell Autophagy via Upregulation of THBS1 and Inactivation of the PI3K/Akt Signaling Pathway in a Rat Sepsis Model., [RefSeq, PubMed]; Targeting Thbs1 reduces bladder remodeling caused by partial bladder outlet obstruction via the FGFR3/p-FGFR3 pathway., [RefSeq, PubMed]; Thrombospondin 1 enhances systemic inflammation and disease severity in acute-on-chronic liver failure. Publication Status: Online-Only, [RefSeq, PubMed]; Thrombospondin-1-mediated crosstalk between autophagy and oxidative stress orchestrates repair of blast lung injury., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 13, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0002020 protease binding;GO:0005178 integrin binding;GO:0008201 heparin binding;GO:0042803 protein homodimerization activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005783 endoplasmic reticulum;GO:0009986 cell surface;GO:0030141 secretory granule;GO:0031012 extracellular matrix", "go_biological_process": "GO:0043032 positive regulation of macrophage activation;GO:0032693 negative regulation of interleukin-10 production;GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis;GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:0006954 inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0G2JV24-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JV96-1", "uniprot_id": [ { "id": "A0A0G2JV96_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JV96", "type": "external" } ], "mass": 34461.0, "length": 307, "protein_name": "Olfactory receptor", "gene_name": "Or5b100", "organism": "Rat", "refseq_name": "olfactory receptor Olr347", "refseq_ac": [ { "id": "NP_001000758", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000758", "type": "external" } ], "gene_names_uniprotkb": "Or5b100", "gene_names_refseq": "Olr347; Or5b100", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 347; olfactory receptor Olr347; olfactory receptor gene Olr347", "tax_id": 10116, "disease": "lysosomal storage disease (Disease Ontology:DOID:3211)", "pathway": " (rno:405031)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JV96-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JVP7-1", "uniprot_id": [ { "id": "A0A0G2JVP7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JVP7", "type": "external" } ], "mass": 13072.0, "length": 115, "protein_name": "40S ribosomal protein S26", "gene_name": "Rps26-ps4", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Rps26-ps4; Rps26-ps12", "gene_names_refseq": "", "protein_names_uniprotkb": "40S ribosomal protein S26", "protein_names_refseq": "", "tax_id": 10116, "disease": "Diamond-Blackfan anemia (Disease Ontology:DOID:1339)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JVP7-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JW56-1", "uniprot_id": [ { "id": "A0A0G2JW56_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JW56", "type": "external" } ], "mass": 7321.0, "length": 71, "protein_name": "Keratin associated protein 6-5", "gene_name": "AABR07033579.3", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "AABR07033579.3", "gene_names_refseq": "", "protein_names_uniprotkb": "Keratin associated protein 6-5", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0005882 intermediate filament", "go_biological_process": "GO:0031424 keratinization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JW56-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JWH3-1", "uniprot_id": [ { "id": "A0A0G2JWH3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JWH3", "type": "external" } ], "mass": 155902.0, "length": 1393, "protein_name": "Condensin complex subunit 1", "gene_name": "Ncapd2", "organism": "Rat", "refseq_name": "condensin complex subunit 1", "refseq_ac": [ { "id": "NP_001386371", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386371", "type": "external" } ], "gene_names_uniprotkb": "Ncapd2", "gene_names_refseq": "Ncapd2; RGD1562596", "protein_names_uniprotkb": "Condensin complex subunit 1", "protein_names_refseq": "condensin complex subunit 1", "tax_id": 10116, "disease": "primary autosomal recessive microcephaly 21 (Disease Ontology:DOID:0051032)", "pathway": " (R-RNO-2514853)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. May target the condensin complex to DNA via its C-terminal domain. May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Required for decatenation of non-centromeric ultrafine DNA bridges during anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042393 histone binding", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:1905820 positive regulation of chromosome separation;GO:0051984 positive regulation of chromosome segregation;GO:0051301 cell division;GO:0007076 mitotic chromosome condensation;GO:0010032 meiotic chromosome condensation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JWH3-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JWK3-1", "uniprot_id": [ { "id": "A0A0G2JWK3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JWK3", "type": "external" } ], "mass": 5592.0, "length": 52, "protein_name": "Uncharacterized protein", "gene_name": "AABR07070669.1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "AABR07070669.1", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JWK3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JWL4-1", "uniprot_id": [ { "id": "A0A0G2JWL4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JWL4", "type": "external" } ], "mass": 68551.0, "length": 625, "protein_name": "FA complementation group G", "gene_name": "Fancg", "organism": "Rat", "refseq_name": "Fanconi anemia group G protein", "refseq_ac": [ { "id": "NP_001414535", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414535", "type": "external" } ], "gene_names_uniprotkb": "Fancg", "gene_names_refseq": "Fancg", "protein_names_uniprotkb": "FA complementation group G", "protein_names_refseq": "Fanconi anemia group G protein; Fanconi anemia, complementation group G", "tax_id": 10116, "disease": "tongue squamous cell carcinoma (Disease Ontology:DOID:0050865); Fanconi anemia complementation group G (Disease Ontology:DOID:0111086); Fanconi anemia (Disease Ontology:DOID:13636); pancreatic cancer (Disease Ontology:DOID:1793)", "pathway": " (R-RNO-6783310); (R-RNO-9833482)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Candidate tumor suppressor gene., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0043240 Fanconi anaemia nuclear complex;GO:0005739 mitochondrion;GO:0016607 nuclear speck;GO:0000785 chromatin", "go_biological_process": "GO:0007286 spermatid development;GO:0006974 DNA damage response;GO:0001541 ovarian follicle development;GO:0007005 mitochondrion organization;GO:0009314 response to radiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JWL4-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JWN4-1", "uniprot_id": [ { "id": "A0A0G2JWN4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JWN4", "type": "external" } ], "mass": 38453.0, "length": 357, "protein_name": "Actin maturation protease", "gene_name": "Actmap", "organism": "Rat", "refseq_name": "actin maturation protease", "refseq_ac": [ { "id": "NP_001333237", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001333237", "type": "external" } ], "gene_names_uniprotkb": "Actmap", "gene_names_refseq": "Actmap; RGD1560854", "protein_names_uniprotkb": "Actin maturation protease; Actin aminopeptidase ACTMAP", "protein_names_refseq": "UPF0692 protein C19orf54 homolog; actin maturation protease", "tax_id": 10116, "disease": "", "pathway": " (rno:499106)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0070005 cysteine-type aminopeptidase activity;GO:0004239 initiator methionyl aminopeptidase activity", "go_cellular_component": "", "go_biological_process": "GO:0016485 protein processing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JWN4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JWU0-1", "uniprot_id": [ { "id": "A0A0G2JWU0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JWU0", "type": "external" } ], "mass": 62468.0, "length": 540, "protein_name": "Zinc finger protein 599", "gene_name": "Zfp599", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Zfp599", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger protein 599", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:103690166); (R-RNO-212436)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JWU0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JX94-1", "uniprot_id": [ { "id": "A0A0G2JX94_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JX94", "type": "external" } ], "mass": 121989.0, "length": 1142, "protein_name": "Angiomotin", "gene_name": "Amot", "organism": "Rat", "refseq_name": "angiomotin isoform 1", "refseq_ac": [ { "id": "NP_001419809", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001419809", "type": "external" } ], "gene_names_uniprotkb": "Amot", "gene_names_refseq": "Amot; RGD1564027", "protein_names_uniprotkb": "Angiomotin", "protein_names_refseq": "angiomotin isoform 1", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-2028269); (R-RNO-9762292)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "29317530;30039887;31325776;31940260", "class_list": "", "function": "AMOT130 linking F-actin to YAP is involved in intervertebral disc degeneration, [RefSeq, PubMed]; AMOT130/YAP mechanotransduction pathway plays a major role in topography-induced bone marrow mesenchymal stem cells osteoblastic differentiation., [RefSeq, PubMed]; Angiomotin links ROCK and YAP signaling in mechanosensitive differentiation of neural stem cells., [RefSeq, PubMed]; The AMOT-130 is essential for normal spine morphogenesis and identifies Lats1 as an upstream regulator in this process. Moreover, It findings may link AMOT-130 loss and the related spine defects to neurological disorders., [RefSeq, PubMed]", "predicted_glycosites": 7, "predicted_n_glycosites": 0, "predicted_o_glycosites": 7, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, 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180 kDa bullous pemphigoid antigen 2; Bullous pemphigoid antigen 2", "protein_names_refseq": "collagen alpha-1(XVII) chain isoform 1; collagen alpha-1(XVII) chain; collagen, type XVII, alpha 1; procollagen, type XVII, alpha 1", "tax_id": 10116, "disease": "junctional epidermolysis bullosa non-Herlitz type (Disease Ontology:DOID:0060738); epithelial recurrent erosion dystrophy (Disease Ontology:DOID:0070337); junctional epidermolysis bullosa (Disease Ontology:DOID:3209)", "pathway": " (rno:294027)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "39265891", "class_list": "", "function": "Junctional Epidermolysis Bullosa in Sprague Dawley Rats Caused by a Frameshift Mutation of Col17a1 Gene., [RefSeq, PubMed]; May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 6, "predicted_n_glycosites": 0, "predicted_o_glycosites": 6, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005604 basement membrane;GO:0030056 hemidesmosome;GO:0016020 membrane", "go_biological_process": "GO:0031581 hemidesmosome assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K449-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K4B1-1", "uniprot_id": [ { "id": "A0A0G2K4B1_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K4B1", "type": "external" } ], "mass": 35689.0, "length": 313, "protein_name": "Olfactory receptor", "gene_name": "Or4p22e", "organism": "Rat", "refseq_name": "olfactory receptor Olr636", "refseq_ac": [ { "id": "NP_001000645", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000645", "type": "external" } ], "gene_names_uniprotkb": "Or4p22e; 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K4B1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K4P1-1", "uniprot_id": [ { "id": "A0A0G2K4P1_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K4P1", "type": "external" } ], "mass": 63573.0, "length": 551, "protein_name": "Sestrin 1", "gene_name": "Sesn1", "organism": "Rat", "refseq_name": "sestrin-1 isoform X2", "refseq_ac": [ { "id": "XP_006256622", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006256622", "type": "external" } ], "gene_names_uniprotkb": "Sesn1", "gene_names_refseq": "Sesn1", "protein_names_uniprotkb": "Sestrin 1", "protein_names_refseq": "sestrin-1 isoform X2", "tax_id": 10116, "disease": "", "pathway": " (rno:294518); (R-RNO-5628897); (R-RNO-9639288); (R-RNO-9755511)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016491 oxidoreductase activity;GO:0070728 L-leucine binding;GO:0016684 oxidoreductase activity, acting on peroxide as acceptor", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0001650 fibrillar center;GO:0061700 GATOR2 complex;GO:0005634 nucleus", "go_biological_process": "GO:0051896 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0030308 negative regulation of cell growth;GO:0042149 cellular response to glucose starvation;GO:0072593 reactive oxygen species metabolic process;GO:0034198 cellular response to amino acid starvation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K4P1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K4W8-1", "uniprot_id": [ { "id": "A0A0G2K4W8_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K4W8", "type": "external" } ], "mass": 91889.0, "length": 836, "protein_name": "Exonuclease 1", "gene_name": "Exo1", "organism": "Rat", "refseq_name": "exonuclease 1", "refseq_ac": [ { "id": "NP_001100668", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100668", "type": "external" } ], "gene_names_uniprotkb": "Exo1", "gene_names_refseq": "Exo1", "protein_names_uniprotkb": "Exonuclease 1; 3.1.-.-", "protein_names_refseq": "exonuclease 1", "tax_id": 10116, "disease": "epilepsy (Disease Ontology:DOID:1826); primary ovarian insufficiency (Disease Ontology:DOID:5426)", "pathway": " (R-RNO-5358565); (R-RNO-5685938); (R-RNO-5685942); (R-RNO-5693537); (R-RNO-5693568); (R-RNO-5693579); (R-RNO-5693607); (R-RNO-5693616); (R-RNO-6804756); (R-RNO-69473)", "pathway_count": 10, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "5'->3' double-stranded DNA exonuclease which may also contain a cryptic 3'->5' double-stranded DNA exonuclease activity. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for DNA mismatch repair (MMR)., [UniProtKB, UniProtKB]; 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "5.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.1", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.1.22.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.22.-", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "6.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.5.1.1", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0046872 metal ion binding;GO:0035312 5'-3' DNA exonuclease activity;GO:0045145 single-stranded DNA 5'-3' DNA exonuclease 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"mass": 35406.0, "length": 317, "protein_name": "Olfactory receptor", "gene_name": "Or5b116b", "organism": "Rat", "refseq_name": "olfactory receptor Olr354", "refseq_ac": [ { "id": "NP_001001045", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001045", "type": "external" } ], "gene_names_uniprotkb": "Or5b116b", "gene_names_refseq": "Olr354; Or5b116b", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 354; olfactory receptor Olr354; olfactory receptor gene Olr354", "tax_id": 10116, "disease": "", "pathway": " (rno:405931)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K6B8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K6M9-1", "uniprot_id": [ { "id": "A0A0G2K6M9_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K6M9", "type": "external" } ], "mass": 76560.0, "length": 661, "protein_name": "Tyrosine-protein kinase", "gene_name": "Btk", "organism": "Rat", "refseq_name": "tyrosine-protein kinase BTK", "refseq_ac": [ { "id": "NP_001007799", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007799", "type": "external" } ], "gene_names_uniprotkb": "Btk", "gene_names_refseq": "Btk", "protein_names_uniprotkb": "Tyrosine-protein kinase; 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Nfkbiz; RGD1310834", "protein_names_uniprotkb": "NF-kappa-B inhibitor zeta; I-kappa-B-zeta; IL-1 inducible nuclear ankyrin-repeat protein; Molecule possessing ankyrin repeats induced by lipopolysaccharide", "protein_names_refseq": "IkappaB-zeta; NF-kappa-B inhibitor zeta; molecule possessing ankyrin-repeats induced by lipopolysaccharide; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta", "tax_id": 10116, "disease": "Stevens-Johnson syndrome (Disease Ontology:DOID:0050426); atopic dermatitis (Disease Ontology:DOID:3310)", "pathway": " (rno:304005)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "28099916", "class_list": "", "function": "Involved in regulation of NF-kappa-B transcription factor complexes. Inhibits NF-kappa-B activity without affecting its nuclear translocation upon stimulation. Inhibits DNA-binding of RELA and NFKB1/p50, and of the NF-kappa-B p65-p50 heterodimer and the NF-kappa-B p50-p50 homodimer. Also seems to activate NF-kappa-B-mediated transcription. In vitro, upon association with NFKB1/p50 has transcriptional activation activity and, together with NFKB1/p50 and RELA, is recruited to LCN2 promoters. Promotes transcription of LCN2 and DEFB4. Is recruited to IL-6 promoters and activates IL-6 but decreases TNF production in response to LPS. Seems to be involved in the induction of inflammatory genes activated through TLR/IL-1 receptor signaling. Involved in the induction of T helper 17 cells (Th17) differentiation upon recognition of antigen by T cell antigen receptor (TCR)., [UniProtKB, UniProtKB]; Suggest role for NF-kappaBIZ in age-associated progressive renal fibrosis via cytokine signaling., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000987 cis-regulatory region sequence-specific DNA binding;GO:0070974 POU domain binding;GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck", "go_biological_process": "GO:0045063 T-helper 1 cell differentiation;GO:0098773 skin epidermis development;GO:0032980 keratinocyte activation;GO:2000321 positive regulation of T-helper 17 cell differentiation;GO:0006338 chromatin remodeling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K6U7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K6W3-1", "uniprot_id": [ { "id": "A0A0G2K6W3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K6W3", "type": "external" } ], "mass": 17132.0, "length": 152, "protein_name": "Sosondowah ankyrin repeat domain family member A", "gene_name": "Sowaha", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Sowaha", "gene_names_refseq": "", "protein_names_uniprotkb": "Sosondowah ankyrin repeat domain family member A", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:497903)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K6W3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K7A5-1", "uniprot_id": [ { "id": "A0A0G2K7A5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K7A5", "type": "external" } ], "mass": 66647.0, "length": 680, "protein_name": "Collagen type X alpha 1 chain", "gene_name": "Col10a1", "organism": "Rat", "refseq_name": "collagen alpha-1(X) chain precursor", "refseq_ac": [ { "id": "NP_037272", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_037272", "type": "external" } ], "gene_names_uniprotkb": "Col10a1", "gene_names_refseq": "Col10a1", "protein_names_uniprotkb": "Collagen type X alpha 1 chain", "protein_names_refseq": "collagen alpha-1(X) chain precursor; 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Probably involved in control of anterograde transport of mitochondria and their subcellular distribution. Promotes mitochondrial fission during high calcium conditions. Can hydrolyze GTP, ATP and UTP., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Miro proteins serve as a [Ca(2+)](c)-sensitive switch and bifunctional regulator for both the motility and fusion-fission dynamics of the mitochondria., [RefSeq, PubMed]; The data point to HDAC6-dependent deacetylation of Miro1 as a mediator of axon growth inhibition through decreased mitochondrial transport., [RefSeq, PubMed]; These data suggest that Miro1 and the kinesin adaptor Grif-1 play an important role in regulating mitochondrial transport in neurons., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, 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"https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "7.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.-", "type": "external" }, { "id": "5.6.1.6", "url": 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activity;GO:0005524 ATP binding;GO:0004707 MAP kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0071493 cellular response to UV-B;GO:0006468 protein phosphorylation;GO:0010628 positive regulation of gene expression;GO:0035556 intracellular signal transduction;GO:0000165 MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2KB06-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P19999-1", "uniprot_id": [ { "id": "MBL1_RAT", "url": "https://www.uniprot.org/uniprot/P19999", "type": "external" } ], "mass": 25308.0, "length": 238, "protein_name": "Mannose-binding protein A", "gene_name": "Mbl1", "organism": "Rat", "refseq_name": "mannose-binding protein A precursor", "refseq_ac": [ { "id": "NP_036731", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_036731", "type": "external" } ], "gene_names_uniprotkb": "Mbl1", "gene_names_refseq": "Mbl1; Mbpa; Mlb1", "protein_names_uniprotkb": "Mannose-binding protein A; MBP-A; Mannan-binding protein", "protein_names_refseq": "MBP-A; Mannose binding protein A, serum; mannan-binding protein; mannose binding lectin (A); mannose binding lectin 1, protein A; mannose binding lectin 2, protein C; mannose-binding lectin (protein A) 1; mannose-binding protein A precursor; mannose-binding protein A", "tax_id": 10116, "disease": "", "pathway": " (rno:24548)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "10903744;10913141;11850428;1436090;1721241;21866632;22879370;25419660;3009480;3029088;3584121;7704532;8636086;9033386;9677372;9922165", "class_list": "", "function": "Calcium-dependent lectin (PubMed:11850428, PubMed:1436090, PubMed:9033386). 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Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]; Our data show an important role for MBL in the pathogenesis of brain ischemic injury and provide a strong support to the concept that MBL inhibition may be a relevant therapeutic target., [RefSeq, PubMed]; The expression of MBL was positively correlated with NF-kappaB expression in diabetic nephropathy., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 4, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 4, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 4, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030247 polysaccharide binding;GO:0070492 oligosaccharide binding;GO:0002020 protease binding;GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005771 multivesicular body;GO:0005576 extracellular region", "go_biological_process": "GO:0043129 surfactant homeostasis;GO:0050830 defense response to Gram-positive bacterium;GO:0050766 positive regulation of phagocytosis;GO:0070207 protein homotrimerization;GO:0001867 complement activation, lectin pathway", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P19999-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000001000.0100000000000.100.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JUM5-1", "uniprot_id": [ { "id": "A0A0G2JUM5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JUM5", "type": "external" } ], "mass": 59995.0, "length": 533, "protein_name": "T-box transcription factor 22", "gene_name": "Tbx22", "organism": "Rat", "refseq_name": "T-box transcription factor TBX22 isoform 1", "refseq_ac": [ { "id": "NP_001421332", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421332", "type": "external" } ], "gene_names_uniprotkb": "Tbx22", "gene_names_refseq": "Tbx 22; 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Fam102b", "gene_names_refseq": "Eeig2; Fam102b; RGD1310037", "protein_names_uniprotkb": "EEIG family member 2", "protein_names_refseq": "EEIG family member 2; family with sequence similarity 102, member B", "tax_id": 10116, "disease": "", "pathway": " (rno:365903)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JVH9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K5B5-1", "uniprot_id": [ { "id": "A0A0G2K5B5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K5B5", "type": "external" } ], "mass": 92861.0, "length": 810, "protein_name": "G-protein coupled receptors family 3 profile domain-containing protein", "gene_name": "ENSRNOG00000068544", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ENSRNOG00000068544; 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(R-RNO-6805567); (R-RNO-6809371)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3ZZI6", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0045295 gamma-catenin binding;GO:1990782 protein tyrosine kinase binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0030054 cell junction;GO:0030057 desmosome", "go_biological_process": "GO:0050770 regulation of axonogenesis;GO:0001701 in utero embryonic development;GO:0098609 cell-cell adhesion;GO:0007416 synapse assembly;GO:0050821 protein stabilization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K230-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZP98-1", "uniprot_id": [ { "id": "D3ZP98_RAT", "url": "https://www.uniprot.org/uniprot/D3ZP98", "type": "external" } ], "mass": 41776.0, "length": 378, "protein_name": "MCTS family member 2", "gene_name": "Hm13", "organism": "Rat", "refseq_name": "minor histocompatibility antigen H13 isoform 2", "refseq_ac": [ { "id": "NP_001386466", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386466", "type": "external" } ], "gene_names_uniprotkb": "Hm13; Mcts2", "gene_names_refseq": "H13; Hm13", "protein_names_uniprotkb": "MCTS family member 2", "protein_names_refseq": "histocompatibility 13; minor histocompatibility antigen H13 isoform 2; minor histocompatibility antigen H13", "tax_id": 10116, "disease": "", "pathway": " (rno:311545); (R-RNO-9707587)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, 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"go_molecular_function": "GO:0042500 aspartic endopeptidase activity, intramembrane cleaving;GO:0042803 protein homodimerization activity;GO:0031625 ubiquitin protein ligase binding;GO:0008233 peptidase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0098554 cytoplasmic side of endoplasmic reticulum membrane;GO:0005783 endoplasmic reticulum;GO:0005791 rough endoplasmic reticulum;GO:0009986 cell surface", "go_biological_process": "GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol;GO:0033619 membrane protein proteolysis;GO:0006465 signal peptide processing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZP98-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZSU3-1", "uniprot_id": [ { "id": "D3ZSU3_RAT", "url": "https://www.uniprot.org/uniprot/D3ZSU3", "type": "external" } ], "mass": 84010.0, "length": 771, "protein_name": "Solute carrier family 7, member 14", "gene_name": "Slc7a14", "organism": "Rat", "refseq_name": "solute carrier family 7 member 14", "refseq_ac": [ { "id": "NP_001425198", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001425198", "type": "external" } ], "gene_names_uniprotkb": "Slc7a14", "gene_names_refseq": "Slc7a14", "protein_names_uniprotkb": "Solute carrier family 7, member 14", "protein_names_refseq": "probable cationic amino acid transporter; solute carrier family 7 (cationic amino acid transporter, y+ system), member 14; solute carrier family 7 (orphan transporter), member 14; solute carrier family 7 member 14", "tax_id": 10116, "disease": "retinitis pigmentosa 68 (Disease Ontology:DOID:0110374); sensorineural hearing loss (Disease Ontology:DOID:10003); blindness (Disease Ontology:DOID:1432)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", 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0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015171 amino acid transmembrane transporter activity;GO:0046943 carboxylic acid transmembrane transporter activity;GO:0015185 gamma-aminobutyric acid transmembrane transporter activity", "go_cellular_component": "GO:0012505 endomembrane system;GO:0005886 plasma membrane;GO:0005765 lysosomal membrane", "go_biological_process": "GO:0006865 amino acid transport;GO:0051939 gamma-aminobutyric acid import", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZSU3-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZY17-1", "uniprot_id": [ { "id": "D3ZY17_RAT", "url": "https://www.uniprot.org/uniprot/D3ZY17", "type": "external" } ], "mass": 92644.0, "length": 827, "protein_name": "Ribosomal protein S6 kinase", "gene_name": "Rps6ka5", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Rps6ka5", "gene_names_refseq": "", "protein_names_uniprotkb": "Ribosomal protein S6 kinase; 2.7.11.1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-198753); (R-RNO-199920); (R-RNO-375165); (R-RNO-5621575)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, 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"2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.34", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" }, { "id": "2.7.11.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.19", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.11.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.4", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.4.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.18", "type": "external" }, { "id": "3.1.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.24.-", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity;GO:0004713 protein tyrosine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0070498 interleukin-1-mediated signaling pathway;GO:0006468 protein phosphorylation;GO:0043687 post-translational protein modification;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZY17-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZFD0-1", "uniprot_id": [ { "id": "MY18A_RAT", "url": "https://www.uniprot.org/uniprot/D3ZFD0", "type": "external" } ], "mass": 232667.0, "length": 2044, "protein_name": "Unconventional myosin-XVIIIa", "gene_name": "Myo18a", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Myo18a", "gene_names_refseq": "", "protein_names_uniprotkb": "Unconventional myosin-XVIIIa", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "16641100;22673903", "class_list": "", "function": "May link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (By similarity). May be involved in the maintenance of the stromal cell architectures required for cell to cell contact (By similarity). Regulates trafficking, expression, and activation of innate immune receptors on macrophages. Plays a role to suppress inflammatory responsiveness of macrophages via a mechanism that modulates CD14 trafficking. Acts as a receptor of surfactant-associated protein A (SFTPA1/SP-A) and plays an important role in internalization and clearance of SFTPA1-opsonized S.aureus by alveolar macrophages. Strongly enhances natural killer cell cytotoxicity (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 32, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0043531 ADP binding;GO:0003774 cytoskeletal motor activity;GO:0003779 actin binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0005903 brush border;GO:0005815 microtubule organizing center", "go_biological_process": "GO:0090164 asymmetric Golgi ribbon formation;GO:0016477 cell migration;GO:0043066 negative regulation of apoptotic process;GO:0050714 positive regulation of protein secretion;GO:0031032 actomyosin structure organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZFD0-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000001000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A4R5-1", "uniprot_id": [ { "id": "D4A4R5_RAT", "url": "https://www.uniprot.org/uniprot/D4A4R5", "type": "external" } ], "mass": 52439.0, "length": 456, "protein_name": "Glycine receptor alpha 4", "gene_name": "Glra4", "organism": "Rat", "refseq_name": "glycine receptor subunit alpha-4 precursor", "refseq_ac": [ { "id": "NP_001178843", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178843", "type": "external" } ], "gene_names_uniprotkb": "Glra4", "gene_names_refseq": "Glra4; RGD1564103", "protein_names_uniprotkb": "Glycine receptor alpha 4", "protein_names_refseq": "glycine receptor subunit alpha-4 precursor; glycine receptor subunit alpha-4; glycine receptor, alpha 4 subunit", "tax_id": 10116, "disease": "", "pathway": " (rno:367912)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "7.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "1.11.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.-", "type": "external" }, { "id": "1.8.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.-.-", "type": "external" }, { "id": "1.8.5.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.5.1", "type": "external" } ], "go_molecular_function": "GO:0022824 transmitter-gated monoatomic ion channel activity;GO:0004888 transmembrane signaling receptor activity;GO:0005254 chloride channel activity;GO:0016594 glycine binding;GO:0016934 extracellularly glycine-gated chloride channel activity", "go_cellular_component": "GO:0045211 postsynaptic membrane;GO:0034707 chloride channel complex;GO:0042995 cell projection;GO:0005886 plasma membrane;GO:0098690 glycinergic synapse", "go_biological_process": "GO:1902476 chloride transmembrane transport;GO:0043200 response to amino acid", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A4R5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZHR8-1", "uniprot_id": [ { "id": "D3ZHR8_RAT", "url": "https://www.uniprot.org/uniprot/D3ZHR8", "type": "external" } ], "mass": 32603.0, "length": 293, "protein_name": "tRNA wybutosine-synthesizing protein 3 homolog", "gene_name": "Tyw3", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Tyw3", "gene_names_refseq": "", "protein_names_uniprotkb": "tRNA wybutosine-synthesizing protein 3 homolog; 2.1.1.282; tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.282", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.282", "type": "external" } ], "go_molecular_function": "GO:0008168 methyltransferase activity;GO:0008175 tRNA methyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0008033 tRNA processing;GO:0032259 methylation;GO:0030488 tRNA methylation;GO:0031591 wybutosine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZHR8-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LPC5-1", "uniprot_id": [ { "id": "F1LPC5_RAT", "url": "https://www.uniprot.org/uniprot/F1LPC5", "type": "external" } ], "mass": 63342.0, "length": 574, "protein_name": "Transmembrane protein 259", "gene_name": "Tmem259", "organism": "Rat", "refseq_name": "membralin", "refseq_ac": [ { "id": "NP_001094356", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094356", "type": "external" } ], "gene_names_uniprotkb": "Tmem259; Mbrl", "gene_names_refseq": "Mbrl; RGD1311136; Tmem259", "protein_names_uniprotkb": "Transmembrane protein 259", "protein_names_refseq": "membralin", "tax_id": 10116, "disease": "", "pathway": " (rno:299608)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "12638133", "class_list": "", "function": "Genomic organization and expression (membralin), [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0034976 response to endoplasmic reticulum stress;GO:1904294 positive regulation of ERAD pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1LPC5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A4E5-1", "uniprot_id": [ { "id": "D4A4E5_RAT", "url": "https://www.uniprot.org/uniprot/D4A4E5", "type": "external" } ], "mass": 92870.0, "length": 833, "protein_name": "Coiled-coil serine-rich protein 2", "gene_name": "Ccser2", "organism": "Rat", "refseq_name": "serine-rich coiled-coil domain-containing protein 2 isoform 1", "refseq_ac": [ { "id": "NP_001414430", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414430", "type": "external" } ], "gene_names_uniprotkb": "Ccser2", "gene_names_refseq": "Ccser2; Fam190b; Gcap14; RGD1304626", "protein_names_uniprotkb": "Coiled-coil serine-rich protein 2", "protein_names_refseq": "family with sequence similarity 190, member B; granule cell antiserum positive 14; protein FAM190B; serine-rich coiled-coil domain-containing protein 2 isoform 1; serine-rich coiled-coil domain-containing protein 2", "tax_id": 10116, "disease": "", "pathway": " (rno:306306)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding", "go_cellular_component": "GO:0015630 microtubule cytoskeleton", "go_biological_process": "GO:0001578 microtubule bundle formation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A4E5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A1T9-1", "uniprot_id": [ { "id": "D4A1T9_RAT", "url": "https://www.uniprot.org/uniprot/D4A1T9", "type": "external" } ], "mass": 35955.0, "length": 327, "protein_name": "Solute carrier family 35 member D2", "gene_name": "Slc35d2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Slc35d2", "gene_names_refseq": "", "protein_names_uniprotkb": "Solute carrier family 35 member D2", "protein_names_refseq": "", "tax_id": 10116, "disease": "depressive disorder (Disease Ontology:DOID:1596)", "pathway": " (rno:290959); (R-RNO-2022854); (R-RNO-2022928); (R-RNO-727802)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015297 antiporter activity;GO:0005338 nucleotide-sugar transmembrane transporter activity;GO:0005461 UDP-glucuronate transmembrane transporter activity;GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity;GO:0005463 UDP-N-acetylgalactosamine transmembrane transporter activity", "go_cellular_component": "GO:0016020 membrane;GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0015012 heparan sulfate proteoglycan biosynthetic process;GO:0015780 nucleotide-sugar transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A1T9-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LPJ7-1", "uniprot_id": [ { "id": "F1LPJ7_RAT", "url": "https://www.uniprot.org/uniprot/F1LPJ7", "type": "external" } ], "mass": 102781.0, "length": 909, "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "Usp33", "organism": "Rat", "refseq_name": "ubiquitin carboxyl-terminal hydrolase 33", "refseq_ac": [ { "id": "NP_001401992", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001401992", "type": "external" } ], "gene_names_uniprotkb": "Usp33", "gene_names_refseq": "Usp33", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase; 3.4.19.12", "protein_names_refseq": "ubiquitin carboxyl-terminal hydrolase 33; ubiquitin specific protease 33", "tax_id": 10116, "disease": "", "pathway": " (rno:310960); (R-RNO-5689880)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "17628004;27156111", "class_list": "", "function": "Correlation between relative mRNA levels of WSB-1 and USP-33 in numerous tissues that do not express type 2 deiodinase(D2) suggests that these ubiquitin-related enzymes share additional substrates besides D2., [RefSeq, PubMed]; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes., [UniProtKB, UniProtKB]; High iodine intake had no discernible effects on USP20. Temporary increases in USP33 and USP19 mRNA levels were observed. The enzymes related to D2 ubiquitination change with prolonged high iodine intake. Increased D2 ubiquitination suppresses the activity of D2, causing a decrease in negative feedback of the hypothalamic-pituitary-thyroid axis., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004843 cysteine-type deubiquitinase activity;GO:0001664 G protein-coupled receptor binding;GO:0031267 small GTPase binding;GO:0004197 cysteine-type endopeptidase activity", "go_cellular_component": "GO:0005813 centrosome;GO:0048471 perinuclear region of cytoplasm;GO:0005794 Golgi apparatus;GO:0044297 cell body", "go_biological_process": "GO:0006508 proteolysis;GO:0006897 endocytosis;GO:0016579 protein deubiquitination;GO:0007399 nervous system development;GO:0016477 cell migration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1LPJ7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZDU2-1", "uniprot_id": [ { "id": "D3ZDU2_RAT", "url": "https://www.uniprot.org/uniprot/D3ZDU2", "type": "external" } ], "mass": 151528.0, "length": 1353, "protein_name": "Regulatory-associated protein of mTOR", "gene_name": "Rptor", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Rptor", "gene_names_refseq": "", "protein_names_uniprotkb": "Regulatory-associated protein of mTOR; p150 target of rapamycin (TOR)-scaffold protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "nicotine dependence (Disease Ontology:DOID:0050742)", "pathway": " (rno:287871); (R-RNO-1632852); (R-RNO-165159); (R-RNO-166208); (R-RNO-3371571); (R-RNO-380972); (R-RNO-5628897); (R-RNO-8943724); (R-RNO-9639288)", "pathway_count": 9, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0019901 protein kinase binding;GO:0030674 protein-macromolecule adaptor activity;GO:0030295 protein kinase activator activity;GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0031931 TORC1 complex;GO:0005764 lysosome;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0030425 dendrite", "go_biological_process": "GO:0031929 TOR signaling;GO:0038202 TORC1 signaling;GO:0023051 regulation of signaling;GO:0010646 regulation of cell communication;GO:0080090 regulation of primary metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZDU2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LP13-1", "uniprot_id": [ { "id": "F1LP13_RAT", "url": "https://www.uniprot.org/uniprot/F1LP13", "type": "external" } ], "mass": 161048.0, "length": 1442, "protein_name": "Receptor-type tyrosine-protein phosphatase gamma", "gene_name": "Ptprg", "organism": "Rat", "refseq_name": "receptor-type tyrosine-protein phosphatase gamma", "refseq_ac": [ { "id": "NP_599183", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_599183", "type": "external" } ], "gene_names_uniprotkb": "Ptprg", "gene_names_refseq": "Ptpg; Ptprg", "protein_names_uniprotkb": "Receptor-type tyrosine-protein phosphatase gamma; 3.1.3.48", "protein_names_refseq": "RPTP gamma A; RPTP gamma B; RPTP gamma C; RPTP gamma S; protein tyrosine phosphatase gamma; receptor-like protein tyrosine phosphatase gamma; receptor-type tyrosine-protein phosphatase gamma", "tax_id": 10116, "disease": "", "pathway": " (rno:171357)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "20014386;38843836", "class_list": "", "function": "Both phosphacan and receptor protein tyrosine phosphatase beta splice variants participate in both the acute degenerative and long-term regenerative phases of reactive synaptogenesis, [RefSeq, PubMed]; Possesses tyrosine phosphatase activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21", "type": "external" }, { "id": "3.1.3.18", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.18", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" }, { "id": "3.1.3.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.5", "type": "external" } ], "go_molecular_function": "GO:0004725 protein tyrosine phosphatase activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0005615 extracellular space", "go_biological_process": "GO:0010633 negative regulation of epithelial cell migration;GO:0007165 signal transduction;GO:0031175 neuron projection development;GO:0010977 negative regulation of neuron projection development", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "F1LP13-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0100000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A168-1", "uniprot_id": [ { "id": "D4A168_RAT", "url": "https://www.uniprot.org/uniprot/D4A168", "type": "external" } ], "mass": 106588.0, "length": 1001, "protein_name": "Zinc finger protein, multitype 1", "gene_name": "Zfpm1", "organism": "Rat", "refseq_name": "zinc finger protein ZFPM1 isoform X1", "refseq_ac": [ { "id": "XP_038953934", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038953934", "type": "external" } ], "gene_names_uniprotkb": "Zfpm1", "gene_names_refseq": "Zfpm1", "protein_names_uniprotkb": "Zinc finger protein, multitype 1", "protein_names_refseq": "zinc finger protein ZFPM1 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-8936459); (R-RNO-983231)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. May be involved in regulation of some genes in gonads. May also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0003714 transcription corepressor activity;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0017053 transcription repressor complex;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0003192 mitral valve formation;GO:0003195 tricuspid valve formation;GO:0010557 positive regulation of macromolecule biosynthetic process;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A168-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K8D1-1", "uniprot_id": [ { "id": "A0A0G2K8D1_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K8D1", "type": "external" } ], "mass": 59743.0, "length": 518, "protein_name": "Motile sperm domain-containing protein 2", "gene_name": "Mospd2", "organism": "Rat", "refseq_name": "motile sperm domain-containing protein 2", "refseq_ac": [ { "id": "NP_001385656", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385656", "type": "external" } ], "gene_names_uniprotkb": "Mospd2", "gene_names_refseq": "Mospd2; RGD1563952", "protein_names_uniprotkb": "Motile sperm domain-containing protein 2", "protein_names_refseq": "motile sperm domain-containing protein 2", "tax_id": 10116, "disease": "", "pathway": " (rno:363463); (R-RNO-6798695)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Endoplasmic reticulum-anchored protein that mediates the formation of contact sites between the endoplasmic (ER) and endosomes, mitochondria or Golgi through interaction with conventional- and phosphorylated-FFAT-containing organelle-bound proteins. In addition, forms endoplasmic reticulum (ER)-lipid droplets (LDs) contacts through a direct protein-membrane interaction and participates in LDs homeostasis. The attachment mechanism involves an amphipathic helix that has an affinity for lipid packing defects present at the surface of LDs. Promotes migration of primary monocytes and neutrophils, in response to various chemokines., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0033149 FFAT motif binding", "go_cellular_component": "GO:0044232 organelle membrane contact site;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0006935 chemotaxis;GO:0051260 protein homooligomerization;GO:0090026 positive regulation of monocyte chemotaxis;GO:0140042 lipid droplet formation;GO:0090023 positive regulation of neutrophil chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K8D1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZQQ1-1", "uniprot_id": [ { "id": "D3ZQQ1_RAT", "url": "https://www.uniprot.org/uniprot/D3ZQQ1", "type": "external" } ], "mass": 98144.0, "length": 905, "protein_name": "Aftiphilin", "gene_name": "Aftph", "organism": "Rat", "refseq_name": "aftiphilin", "refseq_ac": [ { "id": "NP_001292056", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292056", "type": "external" } ], "gene_names_uniprotkb": "Aftph", "gene_names_refseq": "Aftph; RGD1311920", "protein_names_uniprotkb": "Aftiphilin", "protein_names_refseq": "aftiphilin", "tax_id": 10116, "disease": "", "pathway": " (rno:305544)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030276 clathrin binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0032588 trans-Golgi network membrane;GO:0030121 AP-1 adaptor complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZQQ1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZD11-1", "uniprot_id": [ { "id": "D3ZD11_RAT", "url": "https://www.uniprot.org/uniprot/D3ZD11", "type": "external" } ], "mass": 24974.0, "length": 226, "protein_name": "Signal peptidase complex subunit 2", "gene_name": "Spcs2", "organism": "Rat", "refseq_name": "signal peptidase complex subunit 2", "refseq_ac": [ { "id": "NP_001178530", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178530", "type": "external" } ], "gene_names_uniprotkb": "Spcs2", "gene_names_refseq": "RGD1311253; Spcs2", "protein_names_uniprotkb": "Signal peptidase complex subunit 2", "protein_names_refseq": "signal peptidase complex subunit 2", "tax_id": 10116, "disease": "Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (rno:293142); (R-RNO-422085); (R-RNO-9768727)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008233 peptidase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0005787 signal peptidase complex", "go_biological_process": "GO:0045047 protein targeting to ER;GO:0006465 signal peptide processing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZD11-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ABU7-1", "uniprot_id": [ { "id": "D4ABU7_RAT", "url": "https://www.uniprot.org/uniprot/D4ABU7", "type": "external" } ], "mass": 24811.0, "length": 226, "protein_name": "Triggering receptor expressed on myeloid cells 1", "gene_name": "Trem1", "organism": "Rat", "refseq_name": "triggering receptor expressed on myeloid cells 1 precursor", "refseq_ac": [ { "id": "NP_001100355", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100355", "type": "external" } ], "gene_names_uniprotkb": "Trem1", "gene_names_refseq": "Trem1", "protein_names_uniprotkb": "Triggering receptor expressed on myeloid cells 1", "protein_names_refseq": "triggering receptor expressed on myeloid cells 1 precursor", "tax_id": 10116, "disease": "pterygium (Disease Ontology:DOID:0002116); bacterial sepsis (Disease Ontology:DOID:0040085); Stevens-Johnson syndrome (Disease Ontology:DOID:0050426); inflammatory bowel disease (Disease Ontology:DOID:0050589); chorioamnionitis (Disease Ontology:DOID:0050697); diffuse large B-cell lymphoma (Disease Ontology:DOID:0050745); colorectal adenoma (Disease Ontology:DOID:0050860); colorectal adenocarcinoma (Disease Ontology:DOID:0050861); oral squamous cell carcinoma (Disease Ontology:DOID:0050866); medulloblastoma (Disease Ontology:DOID:0050902); myelodysplastic syndrome (Disease Ontology:DOID:0050908); stroke (Disease Ontology:DOID:0051061); pre-malignant neoplasm (Disease Ontology:DOID:0060071); drug allergy (Disease Ontology:DOID:0060500); alcohol-associated liver disease (Disease Ontology:DOID:0070658); hepatic veno-occlusive disease (Disease Ontology:DOID:0080177); colorectal carcinoma (Disease Ontology:DOID:0080199); erythema nodosum (Disease Ontology:DOID:0080750); graft-versus-host disease (Disease Ontology:DOID:0081267); osteonecrosis (Disease Ontology:DOID:10159); thalassemia (Disease Ontology:DOID:10241); prostate cancer (Disease Ontology:DOID:10283); asbestosis (Disease Ontology:DOID:10320); lymphoid leukemia (Disease Ontology:DOID:1037); esophageal atresia (Disease Ontology:DOID:10485); Hirschsprung's disease (Disease Ontology:DOID:10487); stomach cancer (Disease Ontology:DOID:10534); primary open angle glaucoma (Disease Ontology:DOID:1070); Kuhnt-Junius degeneration (Disease Ontology:DOID:10873); hypospadias (Disease Ontology:DOID:10892); urinary bladder cancer (Disease Ontology:DOID:11054); asphyxia neonatorum (Disease Ontology:DOID:11088); Human papillomavirus infectious disease (Disease Ontology:DOID:11166); bronchopulmonary dysplasia (Disease Ontology:DOID:11650); head and neck cancer (Disease Ontology:DOID:11934); allergic disease (Disease Ontology:DOID:1205); optic neuritis (Disease Ontology:DOID:1210); malaria (Disease Ontology:DOID:12365); aplastic anemia (Disease Ontology:DOID:12449); autistic disorder (Disease Ontology:DOID:12849); uterine fibroid (Disease Ontology:DOID:13223); lung cancer (Disease Ontology:DOID:1324); mesenteric vascular occlusion (Disease Ontology:DOID:13252); angle-closure glaucoma (Disease Ontology:DOID:13550); Fanconi anemia (Disease Ontology:DOID:13636); exfoliation syndrome (Disease Ontology:DOID:13641); toxic shock syndrome (Disease Ontology:DOID:14115); Parkinson's disease (Disease Ontology:DOID:14330); aggressive periodontitis (Disease Ontology:DOID:1474); cystic fibrosis (Disease Ontology:DOID:1485); urticaria (Disease Ontology:DOID:1555); acute chest syndrome (Disease Ontology:DOID:1584); depressive disorder (Disease Ontology:DOID:1596); keratosis (Disease Ontology:DOID:161); breast cancer (Disease Ontology:DOID:1612); congenital heart disease (Disease Ontology:DOID:1682); malignant mesothelioma (Disease Ontology:DOID:1790); hepatitis C (Disease Ontology:DOID:1883); hepatitis B (Disease Ontology:DOID:2043); ovary epithelial cancer (Disease Ontology:DOID:2152); multiple sclerosis (Disease Ontology:DOID:2377); larynx cancer (Disease Ontology:DOID:2596); transitional cell carcinoma (Disease Ontology:DOID:2671); asthma (Disease Ontology:DOID:2841); cervix carcinoma (Disease Ontology:DOID:2893); acute pancreatitis (Disease Ontology:DOID:2913); pulmonary tuberculosis (Disease Ontology:DOID:2957); adenocarcinoma (Disease Ontology:DOID:299); malignant astrocytoma (Disease Ontology:DOID:3069); high grade glioma (Disease Ontology:DOID:3070); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); gallbladder cancer (Disease Ontology:DOID:3121); porphyria cutanea tarda (Disease Ontology:DOID:3132); atopic dermatitis (Disease Ontology:DOID:3310); coronary artery disease (Disease Ontology:DOID:3393); middle cerebral artery infarction (Disease Ontology:DOID:3525); toxic encephalopathy (Disease Ontology:DOID:3602); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); pleural empyema (Disease Ontology:DOID:3798); Lynch syndrome (Disease Ontology:DOID:3883); gastritis (Disease Ontology:DOID:4029); bacterial gastritis (Disease Ontology:DOID:4033); systemic scleroderma (Disease Ontology:DOID:418); cervical cancer (Disease Ontology:DOID:4362); macular degeneration (Disease Ontology:DOID:4448); renal cell carcinoma (Disease Ontology:DOID:4450); movement disease (Disease Ontology:DOID:480); small intestine adenocarcinoma (Disease Ontology:DOID:4906); esophagus adenocarcinoma (Disease Ontology:DOID:4914); cholangiocarcinoma (Disease Ontology:DOID:4947); esophageal cancer (Disease Ontology:DOID:5041); melioidosis (Disease Ontology:DOID:5052); liver cirrhosis (Disease Ontology:DOID:5082); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); schizophrenia (Disease Ontology:DOID:5419); oral submucous fibrosis (Disease Ontology:DOID:5773); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); leukopenia (Disease Ontology:DOID:615); hepatocellular carcinoma (Disease Ontology:DOID:684); rheumatoid arthritis (Disease Ontology:DOID:7148); end stage renal disease (Disease Ontology:DOID:783); periodontitis (Disease Ontology:DOID:824); cataract (Disease Ontology:DOID:83); lung disease (Disease Ontology:DOID:850); Hodgkin's lymphoma (Disease Ontology:DOID:8567); infectious mononucleosis (Disease Ontology:DOID:8568); ulcerative colitis (Disease Ontology:DOID:8577); oral cavity cancer (Disease Ontology:DOID:8618); myeloid leukemia (Disease Ontology:DOID:8692); bacterial pneumonia (Disease Ontology:DOID:874); Crohn's disease (Disease Ontology:DOID:8778); skin melanoma (Disease Ontology:DOID:8923); diabetic retinopathy (Disease Ontology:DOID:8947); polycythemia vera (Disease Ontology:DOID:8997); systemic lupus erythematosus (Disease Ontology:DOID:9074); acute myeloid leukemia (Disease Ontology:DOID:9119); amyloidosis (Disease Ontology:DOID:9120); colorectal cancer (Disease Ontology:DOID:9256); nasopharynx carcinoma (Disease Ontology:DOID:9261); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352); bacterial meningitis (Disease Ontology:DOID:9470); multiple myeloma (Disease Ontology:DOID:9538); oral mucosa leukoplakia (Disease Ontology:DOID:9655); senile cataract (Disease Ontology:DOID:9669); pulmonary emphysema (Disease Ontology:DOID:9675); type 1 diabetes mellitus (Disease Ontology:DOID:9744); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (rno:301229); (R-RNO-198933); (R-RNO-202733); (R-RNO-2172127)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "33727099", "class_list": "", "function": "Cell surface receptor that plays important roles in innate and adaptive immunity by amplifying inflammatory responses. Upon activation by various ligands such as PGLYRP1, HMGB1 or HSP70, multimerizes and forms a complex with transmembrane adapter TYROBP/DAP12. In turn, initiates a SYK-mediated cascade of tyrosine phosphorylation, activating multiple downstream mediators such as BTK, MAPK1, MAPK3 or phospholipase C-gamma. This cascade promotes the neutrophil- and macrophage-mediated release of pro-inflammatory cytokines and/or chemokines, as well as their migration and thereby amplifies inflammatory responses that are triggered by bacterial and fungal infections. By also promoting the amplification of inflammatory signals that are initially triggered by Toll-like receptor (TLR) and NOD-like receptor engagement, plays a major role in the pathophysiology of acute and chronic inflammatory diseases of different etiologies including septic shock and atherosclerosis., [UniProtKB, UniProtKB, UniProtKB]; Role of TREM-1 in the development of early brain injury after subarachnoid hemorrhage., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 129, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0097110 scaffold protein binding;GO:0140319 receptor decoy activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005615 extracellular space;GO:0009986 cell surface", "go_biological_process": "GO:0002250 adaptive immune response;GO:0070945 neutrophil-mediated killing of gram-negative bacterium;GO:0016477 cell migration;GO:0045087 innate immune response;GO:0071222 cellular response to lipopolysaccharide", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4ABU7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZWL1-1", "uniprot_id": [ { "id": "D3ZWL1_RAT", "url": "https://www.uniprot.org/uniprot/D3ZWL1", "type": "external" } ], "mass": 76364.0, "length": 677, "protein_name": "SKI-like proto-oncogene", "gene_name": "Skil", "organism": "Rat", "refseq_name": "ski-like protein isoform 1", "refseq_ac": [ { "id": "NP_001385519", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385519", "type": "external" } ], "gene_names_uniprotkb": "Skil", "gene_names_refseq": "Skil; Skir; Sno", "protein_names_uniprotkb": "SKI-like proto-oncogene", "protein_names_refseq": "SKI-like oncogene; ski-like protein isoform 1; ski-like protein; ski/sno related", "tax_id": 10116, "disease": "ureteral obstruction (Disease Ontology:DOID:5199)", "pathway": " (rno:114208); (R-RNO-2173795)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "28765970;29402324;30847937;31028803;37389959", "class_list": "", "function": "BMP7 may ameliorate diabetic nephropathy and renal fibrosis via increasing the expression of SnoN mRNA and protein in renal tubular epithelial cells, rather than directly inhibiting the degradation of SnoN by E3 ubiquitin ligase., [RefSeq, PubMed]; SKIL/SnoN attenuates TGF-beta1/SMAD signaling-dependent collagen synthesis in hepatic fibrosis. Publication Status: Online-Only, [RefSeq, PubMed]; Ski-related novel protein suppresses the development of diabetic nephropathy by modulating kidney transforming growth factor-beta signaling and microRNA-21 expression., [RefSeq, PubMed]; Studied the effects of herbal compound 861 on transforming growth factor beta1 (TGF-beta1)/Sma and Mad-related proteins (Smad)/Ski-related novel protein N (SnoN) signal pathway in a rat hepatic fibrosis disease model. Publication Status: Online-Only, [RefSeq, PubMed]; TAK1 mediated the phosphorylation of Ski-related novel protein N (SnoN), resulting in SnoN ubiquitination and eventual degradation, which enhanced EMT and extracellular matrix deposition to promote renal fibrosis during diabetic nephropathy., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046332 SMAD binding;GO:0003682 chromatin binding;GO:0019904 protein domain specific binding;GO:0042802 identical protein binding;GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0001669 acrosomal vesicle;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway;GO:0002088 lens development in camera-type eye;GO:0002260 lymphocyte homeostasis;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0007283 spermatogenesis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "D3ZWL1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A4K6-1", "uniprot_id": [ { "id": "D4A4K6_RAT", "url": "https://www.uniprot.org/uniprot/D4A4K6", "type": "external" } ], "mass": 196428.0, "length": 1728, "protein_name": "Nebulin-related anchoring protein", "gene_name": "Nrap", "organism": "Rat", "refseq_name": "nebulin-related-anchoring protein isoform X1", "refseq_ac": [ { "id": "XP_006231706", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006231706", "type": "external" } ], "gene_names_uniprotkb": "Nrap", "gene_names_refseq": "Nrap", "protein_names_uniprotkb": "Nebulin-related anchoring protein", "protein_names_refseq": "nebulin-related-anchoring protein isoform X1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0051015 actin filament binding;GO:0051371 muscle alpha-actinin binding;GO:0003779 actin binding;GO:0017166 vinculin binding", "go_cellular_component": "GO:0030018 Z disc;GO:0005916 fascia adherens;GO:0030016 myofibril;GO:0005927 muscle tendon junction", "go_biological_process": "GO:0071691 cardiac muscle thin filament assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A4K6-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E9PTB3-1", "uniprot_id": [ { "id": "E9PTB3_RAT", "url": "https://www.uniprot.org/uniprot/E9PTB3", "type": "external" } ], "mass": 37155.0, "length": 332, "protein_name": "Mitochondrial GTPase 1", "gene_name": "Mtg1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Mtg1; LOC100910751", "gene_names_refseq": "", "protein_names_uniprotkb": "Mitochondrial GTPase 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity. Displays mitochondrial GTPase activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005525 GTP binding;GO:0003924 GTPase activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0005761 mitochondrial ribosome", "go_biological_process": "GO:0070129 regulation of mitochondrial translation;GO:0044065 regulation of respiratory system process;GO:1902775 mitochondrial large ribosomal subunit assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E9PTB3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K9T1-1", "uniprot_id": [ { "id": "A0A0G2K9T1_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K9T1", "type": "external" } ], "mass": 98793.0, "length": 864, "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "Itch", "organism": "Rat", "refseq_name": "E3 ubiquitin-protein ligase Itchy homolog", "refseq_ac": [ { "id": "NP_001005887", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005887", "type": "external" } ], "gene_names_uniprotkb": "Itch", "gene_names_refseq": "Itch", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase; 2.3.2.26", "protein_names_refseq": "E3 ubiquitin-protein ligase Itchy homolog; itch E3 ubiquitin ligase; itchy E3 ubiquitin protein ligase homolog", "tax_id": 10116, "disease": "Liddle syndrome (Disease Ontology:DOID:0050477)", "pathway": " (rno:311567); (R-RNO-1253288); (R-RNO-168638); (R-RNO-2122948); (R-RNO-5610780); (R-RNO-5632684); (R-RNO-5675482); (R-RNO-8939236); (R-RNO-983168)", "pathway_count": 9, "publication_count": 2, "publication_id_list": "26796253;37306338", "class_list": "", "function": "Bone marrow mesenchymal stem cell-derived exosomes carrying E3 ubiquitin ligase ITCH attenuated cardiomyocyte apoptosis by mediating apoptosis signal-regulated kinase-1., [RefSeq, PubMed]; ITCH targets TXNIP for ubiquitin-proteasome degradation in cardiomyocytes and ameliorates reactive oxygen species-induced cardiotoxicity through the thioredoxin system. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "2.3.2.32", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.32", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "2.3.2.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.24", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "3.4.25.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.25.1", "type": "external" } ], "go_molecular_function": "GO:0061630 ubiquitin protein ligase activity;GO:0043021 ribonucleoprotein complex binding;GO:1990763 arrestin family protein binding;GO:0034450 ubiquitin-ubiquitin ligase activity;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0031901 early endosome membrane;GO:0005654 nucleoplasm", "go_biological_process": "GO:1902532 negative regulation of intracellular signal transduction;GO:0045087 innate immune response;GO:0051607 defense response to virus;GO:0006915 apoptotic process;GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2K9T1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZMQ3-1", "uniprot_id": [ { "id": "D3ZMQ3_RAT", "url": "https://www.uniprot.org/uniprot/D3ZMQ3", "type": "external" } ], "mass": 115592.0, "length": 1036, "protein_name": "Integrin alpha-4", "gene_name": "Itga4", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Itga4", "gene_names_refseq": "", "protein_names_uniprotkb": "Integrin alpha-4; 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Satl1", "protein_names_uniprotkb": "Spermidine/spermine N1-acetyl transferase-like 1", "protein_names_refseq": "spermidine/spermine N(1)-acetyltransferase-like protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:302325)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups;GO:0004145 diamine N-acetyltransferase activity;GO:0019809 spermidine binding;GO:0016746 acyltransferase activity", "go_cellular_component": "", "go_biological_process": "GO:0032918 spermidine acetylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZA19-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A917-1", "uniprot_id": [ { "id": "D4A917_RAT", "url": "https://www.uniprot.org/uniprot/D4A917", "type": "external" } ], "mass": 174522.0, "length": 1631, "protein_name": "Latent-transforming growth factor beta-binding protein 4", "gene_name": "Ltbp4", "organism": "Rat", "refseq_name": "latent-transforming growth factor beta-binding protein 4 precursor", "refseq_ac": [ { "id": "NP_001163807", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163807", "type": "external" } ], "gene_names_uniprotkb": "Ltbp4", "gene_names_refseq": "Ltbp4", "protein_names_uniprotkb": "Latent-transforming growth factor beta-binding protein 4", "protein_names_refseq": "latent-transforming growth factor beta-binding protein 4 precursor", "tax_id": 10116, "disease": "autosomal recessive cutis laxa type IC (Disease Ontology:DOID:0070139); cutis laxa (Disease Ontology:DOID:3144)", "pathway": " (rno:292734); (R-RNO-2129379); (R-RNO-2173789)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019838 growth factor binding;GO:0005509 calcium ion binding;GO:0050431 transforming growth factor beta binding", "go_cellular_component": "GO:0031012 extracellular matrix;GO:0005615 extracellular space;GO:0001527 microfibril", "go_biological_process": "GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0046879 hormone secretion;GO:0048251 elastic fiber assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A917-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LVK0-1", "uniprot_id": [ { "id": "F1LVK0_RAT", "url": "https://www.uniprot.org/uniprot/F1LVK0", "type": "external" } ], "mass": 558443.0, "length": 5042, "protein_name": "Bridge-like lipid transfer protein family member 1", "gene_name": "Bltp1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Bltp1; 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Ly49s8", "organism": "Rat", "refseq_name": "killer cell lectin-like receptor, subfamily A, member 5 isoform X1", "refseq_ac": [ { "id": "XP_038963383", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038963383", "type": "external" } ], "gene_names_uniprotkb": "Klra5; Ly49s8; LOC100911234; LOC134486851; Ly49s8", "gene_names_refseq": "Klra5; Ly-49.9", "protein_names_uniprotkb": "Ly49 stimulatory receptor 8", "protein_names_refseq": "killer cell lectin-like receptor, subfamily A, member 5 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:297666)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030246 carbohydrate binding;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0007155 cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E9PTN0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LSH0-1", "uniprot_id": [ { "id": "F1LSH0_RAT", "url": "https://www.uniprot.org/uniprot/F1LSH0", "type": "external" } ], "mass": 142128.0, "length": 1280, "protein_name": "Symplekin", "gene_name": "Sympk", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Sympk", "gene_names_refseq": "", "protein_names_uniprotkb": "Symplekin", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:292683); (R-RNO-159231); (R-RNO-73856); (R-RNO-77595); (R-RNO-9770562)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Scaffold protein that functions as a component of a multimolecular complex involved in histone mRNA 3'-end processing. Specific component of the tight junction (TJ) plaque, but might not be an exclusively junctional component. May have a house-keeping rule. Is involved in pre-mRNA polyadenylation. Enhances SSU72 phosphatase activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0097165 nuclear stress granule;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0016604 nuclear body", "go_biological_process": "GO:0031124 mRNA 3'-end processing;GO:0006397 mRNA processing;GO:0007155 cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1LSH0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1B0GWP1-1", "uniprot_id": [ { "id": "A0A1B0GWP1_RAT", "url": "https://www.uniprot.org/uniprot/A0A1B0GWP1", "type": "external" } ], "mass": 47306.0, "length": 412, "protein_name": "Elongation of very long chain fatty acids protein 1", "gene_name": "Elovl1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Elovl1; ELOVL1", "gene_names_refseq": "", "protein_names_uniprotkb": "Elongation of very long chain fatty acids protein 1; 2.3.1.199; 3-keto acyl-CoA synthase ELOVL1; ELOVL FA elongase 1; ELOVL fatty acid elongase 1; Very long chain 3-ketoacyl-CoA synthase 1; Very long chain 3-oxoacyl-CoA synthase 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "adrenoleukodystrophy (Disease Ontology:DOID:10588)", "pathway": " (R-RNO-2046105); (R-RNO-2046106); (R-RNO-75876)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.199", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.199", "type": "external" } ], "go_molecular_function": "GO:0009922 fatty acid elongase activity", "go_cellular_component": "GO:0016020 membrane;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006633 fatty acid biosynthetic process;GO:0046513 ceramide biosynthetic process;GO:0061436 establishment of skin barrier;GO:0030148 sphingolipid biosynthetic process;GO:0035338 long-chain fatty-acyl-CoA biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1B0GWP1-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KAS0-1", "uniprot_id": [ { "id": "A0A0G2KAS0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KAS0", "type": "external" } ], "mass": 128021.0, "length": 1188, "protein_name": "Calpain-15", "gene_name": "Capn15", "organism": "Rat", "refseq_name": "calpain-15 isoform 2", "refseq_ac": [ { "id": "NP_001426651", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001426651", "type": "external" } ], "gene_names_uniprotkb": "Capn15; Solh", "gene_names_refseq": "Capn15; Solh", "protein_names_uniprotkb": "Calpain-15; Small optic lobes homolog", "protein_names_refseq": "calpain-15 isoform 2; small optic lobes homolog", "tax_id": 10116, "disease": "", "pathway": " (rno:303000); (R-RNO-1474228)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004198 calcium-dependent cysteine-type endopeptidase activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2KAS0-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZJ25-1", "uniprot_id": [ { "id": "AAAT_RAT", "url": "https://www.uniprot.org/uniprot/D3ZJ25", "type": "external" } ], "mass": 58477.0, "length": 555, "protein_name": "Neutral amino acid transporter B(0)", "gene_name": "Slc1a5", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Slc1a5", "gene_names_refseq": "", "protein_names_uniprotkb": "Neutral amino acid transporter B(0); ASC-like Na(+)-dependent neutral amino acid transporter ASCT2; ATB(0); Insulin-activated amino acid transporter; Sodium-dependent neutral amino acid transporter type 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "tongue squamous cell carcinoma (Disease Ontology:DOID:0050865); episodic ataxia type 6 (Disease Ontology:DOID:0050994); neurodegenerative disease (Disease Ontology:DOID:1289); epilepsy (Disease Ontology:DOID:1826); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung adenocarcinoma (Disease Ontology:DOID:3910); pulmonary hypertension (Disease Ontology:DOID:6432)", "pathway": " (rno:292657); (R-RNO-352230); (R-RNO-9013149); (R-RNO-9013406); (R-RNO-9013407); (R-RNO-9013423)", "pathway_count": 6, "publication_count": 2, "publication_id_list": "10698697;22673903", "class_list": "", "function": "Sodium-coupled antiporter of neutral amino acids. In a tri-substrate transport cycle, exchanges neutral amino acids between the extracellular and intracellular compartments, coupled to the inward cotransport of at least one sodium ion (By similarity) (PubMed:10698697). The preferred substrate is the essential amino acid L-glutamine, a precursor for biosynthesis of proteins, nucleotides and amine sugars as well as an alternative fuel for mitochondrial oxidative phosphorylation. Exchanges L-glutamine with other neutral amino acids such as L-serine, L-threonine and L-asparagine in a bidirectional way. Provides L-glutamine to proliferating stem and activated cells driving the metabolic switch toward cell differentiation (By similarity). The transport cycle is usually pH-independent, with the exception of L-glutamate. Transports extracellular L-glutamate coupled to the cotransport of one proton and one sodium ion in exchange for intracellular L-glutamine counter-ion. May provide for L-glutamate uptake in glial cells regulating glutamine/glutamate cycle in the nervous system (By similarity). Part of transport systems for D-amino acids. Mediates D-serine release from the retinal glia potentially affecting NMDA receptor function in retinal neurons. May contribute to D-serine reabsorption at the brush border of renal proximal tubules thus modulating the dynamics of urinary versus blood D-serine levels (By similarity). Displays sodium- and amino acid-dependent but uncoupled channel-like anion conductance with a preference SCN(-) >> NO3(-) > I(-) > Cl(-) (PubMed:10698697). Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (By similarity)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.8.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.-.-", "type": "external" }, { "id": "1.8.5.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.5.1", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0015175 neutral L-amino acid transmembrane transporter activity;GO:0015186 L-glutamine transmembrane transporter activity;GO:0015194 L-serine transmembrane transporter activity;GO:0015293 symporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0042470 melanosome;GO:0009925 basal plasma membrane", "go_biological_process": "GO:0015825 L-serine transport;GO:0030218 erythrocyte differentiation;GO:0006868 glutamine transport;GO:0010585 glutamine secretion;GO:0015804 neutral amino acid transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZJ25-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZXX3-1", "uniprot_id": [ { "id": "D3ZXX3_RAT", "url": "https://www.uniprot.org/uniprot/D3ZXX3", "type": "external" } ], "mass": 370837.0, "length": 3332, "protein_name": "Unc-80 homolog, NALCN channel complex subunit", "gene_name": "Unc80", "organism": "Rat", "refseq_name": "protein unc-80 homolog isoform X7", "refseq_ac": [ { "id": "XP_038940528", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038940528", "type": "external" } ], "gene_names_uniprotkb": "Unc80", "gene_names_refseq": "Unc80", "protein_names_uniprotkb": "Unc-80 homolog, NALCN channel complex subunit", "protein_names_refseq": "protein unc-80 homolog isoform X7", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-2672351)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "38843836", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005261 monoatomic cation channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0034706 sodium channel complex;GO:0001518 voltage-gated sodium channel complex;GO:0034703 cation channel complex;GO:0030424 axon", "go_biological_process": "GO:0035725 sodium ion transmembrane transport;GO:0098908 regulation of neuronal action potential;GO:0055080 monoatomic cation homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "D3ZXX3-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000000001000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LS35-1", "uniprot_id": [ { "id": "F1LS35_RAT", "url": "https://www.uniprot.org/uniprot/F1LS35", "type": "external" } ], "mass": 126282.0, "length": 1126, "protein_name": "Hermansky-Pudlak syndrome 5 protein homolog", "gene_name": "Hps5", "organism": "Rat", "refseq_name": "BLOC-2 complex member HPS5", "refseq_ac": [ { "id": "NP_001129084", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001129084", "type": "external" } ], "gene_names_uniprotkb": "Hps5; Saa4", "gene_names_refseq": "Aa2-028; Ab1-018; Hps5", "protein_names_uniprotkb": "Hermansky-Pudlak syndrome 5 protein homolog", "protein_names_refseq": "BLOC-2 complex member HPS5; Hermansky-Pudlak syndrome 5", "tax_id": 10116, "disease": "Hermansky-Pudlak syndrome 5 (Disease Ontology:DOID:0060543); platelet storage pool deficiency (Disease Ontology:DOID:2223); Hermansky-Pudlak syndrome (Disease Ontology:DOID:3753)", "pathway": " (rno:308598)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "29393594", "class_list": "", "function": "May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Regulates intracellular vesicular trafficking in fibroblasts. May be involved in the regulation of general functions of integrins., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0031084 BLOC-2 complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0007596 blood coagulation;GO:0043473 pigmentation;GO:0048066 developmental pigmentation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1LS35-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZXB0-1", "uniprot_id": [ { "id": "D3ZXB0_RAT", "url": "https://www.uniprot.org/uniprot/D3ZXB0", "type": "external" } ], "mass": 47381.0, "length": 424, "protein_name": "Probable thioesterase PNKD", "gene_name": "Pnkd", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Pnkd", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable thioesterase PNKD; Myofibrillogenesis regulator 1; Paroxysmal nonkinesiogenic dyskinesia protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "paroxysmal nonkinesigenic dyskinesia 1 (Disease Ontology:DOID:0090049)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "38843836", "class_list": "", "function": "Probable thioesterase that may play a role in cellular detoxification processes; it likely acts on a yet-unknown alpha-hydroxythioester substrate. In vitro, it is able to catalyze the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid at very low rate, though this reaction is not physiologically relevant in vivo., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004416 hydroxyacylglutathione hydrolase activity;GO:0046872 metal ion binding;GO:0016790 thiolester hydrolase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0099523 presynaptic cytosol", "go_biological_process": "GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione;GO:0032225 regulation of synaptic transmission, dopaminergic;GO:0042053 regulation of dopamine metabolic process;GO:0046929 negative regulation of neurotransmitter secretion;GO:0050884 neuromuscular process controlling posture", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "D3ZXB0-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.000000000000001000.0100000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E9PU41-1", "uniprot_id": [ { "id": "E9PU41_RAT", "url": "https://www.uniprot.org/uniprot/E9PU41", "type": "external" } ], "mass": 83121.0, "length": 707, "protein_name": "Zinc finger protein 846", "gene_name": "Znf846", "organism": "Rat", "refseq_name": "uncharacterized protein LOC304336 isoform X1", "refseq_ac": [ { "id": "XP_038945325", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038945325", "type": "external" } ], "gene_names_uniprotkb": "Znf846; RGD1566386", "gene_names_refseq": "RGD1566386; Znf846", "protein_names_uniprotkb": "Zinc finger protein 846", "protein_names_refseq": "uncharacterized protein LOC304336 isoform X1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", 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"2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.34", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" }, { "id": "2.7.11.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.19", "type": "external" 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"external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004709 MAP kinase kinase kinase activity;GO:0106310 protein serine kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0004706 JUN kinase kinase kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006468 protein phosphorylation;GO:0007165 signal transduction;GO:0043065 positive regulation of apoptotic process;GO:0046777 protein autophosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LRA7-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZFT1-1", "uniprot_id": [ { "id": "D3ZFT1_RAT", "url": "https://www.uniprot.org/uniprot/D3ZFT1", "type": "external" } ], "mass": 125728.0, "length": 1131, "protein_name": "Replication factor C subunit 1", "gene_name": "Rfc1", "organism": "Rat", "refseq_name": "replication factor C subunit 1 isoform X6", "refseq_ac": [ { "id": "XP_038948446", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038948446", "type": "external" } ], "gene_names_uniprotkb": "Rfc1", "gene_names_refseq": "Recc1; Rfc1", "protein_names_uniprotkb": "Replication factor C subunit 1", "protein_names_refseq": "replication factor C subunit 1 isoform X6", "tax_id": 10116, "disease": "cerebellar ataxia, neuropathy, and vestibular areflexia syndrome (Disease Ontology:DOID:0070148); congenital heart disease (Disease Ontology:DOID:1682); West Nile fever (Disease Ontology:DOID:2366)", 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This subunit binds to the primer-template junction. Binds the PO-B transcription element as well as other GA rich DNA sequences. Can bind single- or double-stranded DNA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003689 DNA clamp loader activity;GO:0019904 protein domain specific binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005663 DNA replication factor C complex;GO:0005654 nucleoplasm;GO:0032991 protein-containing complex;GO:0031391 Elg1 RFC-like complex", "go_biological_process": "GO:0006281 DNA repair;GO:0006260 DNA replication;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "D3ZFT1-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LNX8-1", "uniprot_id": [ { "id": "F1LNX8_RAT", "url": "https://www.uniprot.org/uniprot/F1LNX8", "type": "external" } ], "mass": 66980.0, "length": 578, "protein_name": "Cytidine monophosphate-N-acetylneuraminic acid hydroxylase", "gene_name": "Cmah", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Cmah; Cmahp", "gene_names_refseq": "", "protein_names_uniprotkb": "Cytidine monophosphate-N-acetylneuraminic acid hydroxylase; 1.14.18.2; CMP-N-acetylneuraminate monooxygenase; CMP-Neu5Ac hydroxylase; CMP-NeuAc hydroxylase", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell-pathogen interactions. Catalyzes the conversion of CMP-N-acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.18.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.18.2", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0051537 2 iron, 2 sulfur cluster binding;GO:0030338 CMP-N-acetylneuraminate monooxygenase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0016020 membrane", "go_biological_process": "GO:0006054 N-acetylneuraminate metabolic process;GO:0030111 regulation of Wnt signaling pathway;GO:0046381 CMP-N-acetylneuraminate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LNX8-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZMZ8-1", "uniprot_id": [ { "id": "D3ZMZ8_RAT", "url": "https://www.uniprot.org/uniprot/D3ZMZ8", "type": "external" } ], "mass": 21555.0, "length": 201, "protein_name": "Interferon induced transmembrane protein 10", "gene_name": "Ifitm10", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ifitm10", "gene_names_refseq": "", "protein_names_uniprotkb": "Interferon induced transmembrane protein 10", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZMZ8-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZJR7-1", "uniprot_id": [ { "id": "D3ZJR7_RAT", "url": "https://www.uniprot.org/uniprot/D3ZJR7", "type": "external" } ], "mass": 100050.0, "length": 902, "protein_name": "Desmocollin 2", "gene_name": "Dsc2", "organism": "Rat", "refseq_name": "desmocollin-2 precursor", "refseq_ac": [ { "id": "NP_001028860", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001028860", "type": "external" } ], "gene_names_uniprotkb": "Dsc2", "gene_names_refseq": "Dsc2", "protein_names_uniprotkb": "Desmocollin 2", "protein_names_refseq": "desmocollin-2 precursor", "tax_id": 10116, "disease": "arrhythmogenic right ventricular cardiomyopathy (Disease Ontology:DOID:0050431); 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"A0A0G2KAI3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KAI3", "type": "external" } ], "mass": 54599.0, "length": 492, "protein_name": "Cytochrome P450 2W1", "gene_name": "Cyp2w1", "organism": "Rat", "refseq_name": "cytochrome P450, family 2, subfamily w, polypeptide 1", "refseq_ac": [ { "id": "NP_001414598", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414598", "type": "external" } ], "gene_names_uniprotkb": "Cyp2w1", "gene_names_refseq": "Cyp2w1", "protein_names_uniprotkb": "Cytochrome P450 2W1", "protein_names_refseq": "cytochrome P450 2W1; cytochrome P450, family 2, subfamily w, polypeptide 1", "tax_id": 10116, "disease": "", "pathway": " (rno:288517); (R-RNO-211958); (R-RNO-211981)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "16426568", "class_list": "", "function": "CYP2W1 is expressed human colonic and adrenal gland neoplasms, but not normal tissue, and is expressed in rat fetal and adult colon, [RefSeq, PubMed]", "predicted_glycosites": 0, 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"glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.14.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.-", "type": "external" }, { "id": "1.14.13.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.-", "type": "external" } ], "go_molecular_function": "GO:0008401 retinoic acid 4-hydroxylase activity;GO:0005506 iron ion binding;GO:0005503 all-trans retinal binding;GO:0020037 heme binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005788 endoplasmic reticulum lumen;GO:0009986 cell surface;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006805 xenobiotic metabolic process;GO:0006644 phospholipid metabolic process;GO:0006082 organic acid metabolic process;GO:0034653 retinoic acid catabolic process;GO:0046222 aflatoxin metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KAI3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KB74-1", "uniprot_id": [ { "id": "A0A0G2KB74_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KB74", "type": "external" } ], "mass": 165209.0, "length": 1523, "protein_name": "Disco-interacting protein 2 homolog A", "gene_name": "Dip2a", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Dip2a", "gene_names_refseq": "", "protein_names_uniprotkb": "Disco-interacting protein 2 homolog A", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, 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"secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003987 acetate-CoA ligase activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005739 mitochondrion;GO:0009986 cell surface;GO:0016020 membrane;GO:0043197 dendritic spine", "go_biological_process": "GO:0010629 negative regulation of gene expression;GO:0006085 acetyl-CoA biosynthetic process;GO:0060997 dendritic spine morphogenesis;GO:2000758 positive regulation of peptidyl-lysine acetylation;GO:1905274 regulation of modification of postsynaptic actin cytoskeleton", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2KB74-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2QC64-1", "uniprot_id": [ { "id": "A0A0G2QC64_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2QC64", "type": "external" } ], "mass": 57896.0, "length": 537, "protein_name": "Cytoplasmic dynein 2 intermediate chain 2", "gene_name": "Dync2i2", "organism": "Rat", "refseq_name": "cytoplasmic dynein 2 intermediate chain 2", "refseq_ac": [ { "id": "NP_001005542", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005542", "type": "external" } ], "gene_names_uniprotkb": "Dync2i2; Wdr34", "gene_names_refseq": "Dync2i2; Wdr34", "protein_names_uniprotkb": "Cytoplasmic dynein 2 intermediate chain 2; Dynein 2 intermediate chain 2; WD repeat-containing protein 34", "protein_names_refseq": "WD repeat domain 34; WD repeat-containing protein 34; cytoplasmic dynein 2 intermediate chain 2", "tax_id": 10116, "disease": "neural tube defect (Disease Ontology:DOID:0080074); short-rib thoracic dysplasia 11 with or without polydactyly (Disease Ontology:DOID:0110095)", "pathway": " (rno:296618); (R-RNO-5620924)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Inhibits the MAP3K7-induced NF-kappa-B activation pathway. Inhibits MAP3K7 phosphorylation at 'Thr-184' and 'Thr-187' upon Il-1 beta stimulation., [UniProtKB, UniProtKB]; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 2 complex (dynein-2 complex), a motor protein complex that drives the movement of cargos along microtubules within cilia and flagella in concert with the intraflagellar transport (IFT) system. DYNC2I2 plays a major role in retrograde ciliary protein trafficking and in ciliogenesis. Required also to maintain a functional transition zone., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0045503 dynein light chain binding;GO:0045504 dynein heavy chain binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005829 cytosol;GO:0005929 cilium;GO:0030175 filopodium", "go_biological_process": "GO:0060271 cilium assembly;GO:0042073 intraciliary transport;GO:0035721 intraciliary retrograde transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2QC64-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140UHX1-1", "uniprot_id": [ { "id": "A0A140UHX1_RAT", "url": "https://www.uniprot.org/uniprot/A0A140UHX1", "type": "external" } ], "mass": 71300.0, "length": 648, "protein_name": "Leucine-rich repeat and WD repeat-containing protein 1", "gene_name": "Lrwd1", "organism": "Rat", "refseq_name": "leucine-rich repeat and WD repeat-containing protein 1", "refseq_ac": [ { "id": "NP_001014003", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014003", "type": "external" } ], "gene_names_uniprotkb": "Lrwd1", "gene_names_refseq": "Lrwd1", "protein_names_uniprotkb": "Leucine-rich repeat and WD repeat-containing protein 1; Origin recognition complex-associated protein", "protein_names_refseq": "leucine-rich repeat and WD repeat-containing protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:304396)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "37551430", "class_list": "", "function": "Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0008327 methyl-CpG binding;GO:0061628 histone H3K27me3 reader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005813 centrosome;GO:0000776 kinetochore", "go_biological_process": "GO:0006260 DNA replication;GO:0006325 chromatin organization;GO:0071169 establishment of protein localization to chromatin", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140UHX1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1B0GWR7-1", "uniprot_id": [ { "id": "A0A1B0GWR7_RAT", "url": "https://www.uniprot.org/uniprot/A0A1B0GWR7", "type": "external" } ], "mass": 54104.0, "length": 520, "protein_name": "Mex-3 RNA binding family member A", "gene_name": "Mex3a", "organism": "Rat", "refseq_name": "RNA-binding protein MEX3A", "refseq_ac": [ { "id": "NP_001385668", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385668", "type": "external" } ], "gene_names_uniprotkb": "Mex3a", "gene_names_refseq": "Mex3a; RGD1564904", "protein_names_uniprotkb": "Mex-3 RNA binding family member A", "protein_names_refseq": "RNA-binding protein MEX3A; mex3 homolog A", "tax_id": 10116, "disease": "", "pathway": " (rno:310631)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0000932 P-body", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1B0GWR7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1B0GWR9-1", "uniprot_id": [ { "id": "A0A1B0GWR9_RAT", "url": "https://www.uniprot.org/uniprot/A0A1B0GWR9", "type": "external" } ], "mass": 135299.0, "length": 1194, "protein_name": "Phospholipid-transporting ATPase", "gene_name": "Atp8b4", "organism": "Rat", "refseq_name": "probable phospholipid-transporting ATPase IM", "refseq_ac": [ { "id": "NP_001417363", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417363", "type": "external" } ], "gene_names_uniprotkb": "Atp8b4", "gene_names_refseq": "Atp8b4", "protein_names_uniprotkb": "Phospholipid-transporting ATPase; 7.6.2.1", "protein_names_refseq": "ATPase, class I, type 8B, member 4; probable phospholipid-transporting ATPase IM", "tax_id": 10116, "disease": "progressive familial intrahepatic cholestasis (Disease Ontology:DOID:0070221)", "pathway": " (rno:311396); (R-RNO-6798695); (R-RNO-936837)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "7.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.1", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "1.14.14.18", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.18", "type": "external" }, { "id": "3.4.21.73", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.73", "type": "external" }, { "id": "1.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.-", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "6.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.3", "type": "external" }, { "id": "6.2.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.-", "type": "external" }, { "id": "6.2.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.7", "type": "external" }, { "id": "6.2.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.24", "type": "external" }, { "id": "6.2.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.15", "type": "external" }, { "id": "3.4.24.81", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.81", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "1.2.1.5", "url": 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"predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0016604 nuclear body;GO:0001669 acrosomal vesicle", "go_biological_process": "GO:0031619 homologous chromosome orientation in meiotic metaphase I;GO:0007059 chromosome segregation;GO:0008608 attachment of spindle microtubules to kinetochore;GO:0051301 cell division;GO:0006909 phagocytosis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3Z896-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3Z8K5-1", "uniprot_id": [ { "id": "D3Z8K5_RAT", "url": "https://www.uniprot.org/uniprot/D3Z8K5", "type": "external" } ], "mass": 115964.0, "length": 1041, "protein_name": "ubiquitinyl hydrolase 1", "gene_name": "Usp38", "organism": "Rat", "refseq_name": "ubiquitin carboxyl-terminal hydrolase 38", "refseq_ac": [ { "id": "NP_001100888", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100888", "type": "external" } ], "gene_names_uniprotkb": "Usp38", "gene_names_refseq": "Usp38", "protein_names_uniprotkb": "ubiquitinyl hydrolase 1; 3.4.19.12", "protein_names_refseq": "ubiquitin carboxyl-terminal hydrolase 38; ubiquitin specific protease 38", "tax_id": 10116, "disease": "", "pathway": " (rno:307764)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0031647 regulation of protein stability;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0045824 negative regulation of innate immune response;GO:1990168 protein K33-linked deubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3Z8K5-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3Z8N7-1", "uniprot_id": [ { "id": "D3Z8N7_RAT", "url": "https://www.uniprot.org/uniprot/D3Z8N7", "type": "external" } ], "mass": 64974.0, "length": 576, "protein_name": "F-box protein 15", "gene_name": "Fbxo15", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Fbxo15; AABR07064622.1", "gene_names_refseq": "", "protein_names_uniprotkb": "F-box protein 15", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-8951664); (R-RNO-983168)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Nucleic acid-binding protein which is essential for retrotransposition of LINE-1 elements in the genome. Functions as a nucleic acid chaperone binding its own transcript and therefore preferentially mobilizing the transcript from which they are encoded., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000166 nucleotide binding;GO:0003727 single-stranded RNA binding", "go_cellular_component": "GO:0019005 SCF ubiquitin ligase complex;GO:0005730 nucleolus;GO:0010494 cytoplasmic stress granule;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0032197 retrotransposition", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3Z8N7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3Z8X4-1", "uniprot_id": [ { "id": "D3Z8X4_RAT", "url": "https://www.uniprot.org/uniprot/D3Z8X4", "type": "external" } ], "mass": 262143.0, "length": 2283, "protein_name": "DNA polymerase epsilon catalytic subunit", "gene_name": "Pole", "organism": "Rat", "refseq_name": "DNA polymerase epsilon catalytic subunit A", "refseq_ac": [ { "id": "NP_001100622", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100622", "type": "external" } ], "gene_names_uniprotkb": "Pole", "gene_names_refseq": "POLE1; Pole", "protein_names_uniprotkb": "DNA polymerase epsilon catalytic subunit; 2.7.7.7", "protein_names_refseq": "DNA polymerase epsilon catalytic subunit A; DNA-directed DNA polymerase epsilon; polymerase (DNA directed), epsilon, catalytic subunit; polymerase (DNA) epsilon, catalytic subunit", "tax_id": 10116, "disease": "mismatch repair cancer syndrome (Disease Ontology:DOID:0112182); duodenum cancer (Disease Ontology:DOID:10021); prostate cancer (Disease Ontology:DOID:10283); lung cancer (Disease Ontology:DOID:1324); endometrial cancer (Disease Ontology:DOID:1380); cancer (Disease Ontology:DOID:162); ascending colon cancer (Disease Ontology:DOID:218); ovarian cancer (Disease Ontology:DOID:2394); kidney cancer (Disease Ontology:DOID:263); endometrial carcinoma (Disease Ontology:DOID:2871); glioblastoma (Disease Ontology:DOID:3068); high grade glioma (Disease Ontology:DOID:3070); anaplastic astrocytoma (Disease Ontology:DOID:3078); breast carcinoma (Disease Ontology:DOID:3459); liver cancer (Disease Ontology:DOID:3571); gastric adenocarcinoma (Disease Ontology:DOID:3717); lung squamous cell carcinoma (Disease Ontology:DOID:3907); lung non-small cell carcinoma (Disease Ontology:DOID:3908); pleomorphic xanthoastrocytoma (Disease Ontology:DOID:4852); endometrial serous adenocarcinoma (Disease Ontology:DOID:5750); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (rno:304573); (R-RNO-110314); (R-RNO-5651801); (R-RNO-5656169); (R-RNO-5685942); (R-RNO-5693537); (R-RNO-5696397); (R-RNO-5696400); (R-RNO-6782135); (R-RNO-6782210); (R-RNO-68952); (R-RNO-68962)", "pathway_count": 12, "publication_count": 2, "publication_id_list": "16641100;29393594", "class_list": "", "function": "DNA polymerase II participates in chromosomal DNA replication., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 21, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "6.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.5.1.1", "type": "external" }, { "id": "2.3.2.32", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.32", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" }, { "id": "2.4.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.-", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.7.102", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.102", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "5.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.1", "type": "external" }, { "id": "2.7.7.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.31", "type": "external" }, { "id": "2.7.7.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.-", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "4.2.99.-", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.-", "type": "external" }, { "id": "2.4.2.30", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.30", "type": "external" }, { "id": "3.1.11.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.2", "type": "external" }, { "id": "3.1.21.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.21.-", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" } ], "go_molecular_function": "GO:0003887 DNA-directed DNA polymerase activity;GO:0008310 single-stranded DNA 3'-5' DNA exonuclease activity;GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0008622 epsilon DNA polymerase complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0071897 DNA biosynthetic process;GO:0006272 leading strand elongation;GO:0006297 nucleotide-excision repair, DNA gap filling;GO:0006287 base-excision repair, gap-filling;GO:0045004 DNA replication proofreading", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3Z8X4-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3Z930-1", "uniprot_id": [ { "id": "D3Z930_RAT", "url": "https://www.uniprot.org/uniprot/D3Z930", "type": "external" } ], "mass": 52061.0, "length": 461, "protein_name": "Ribosome assembly protein METTL17, mitochondrial", "gene_name": "Mettl17", "organism": "Rat", "refseq_name": "methyltransferase-like protein 17, mitochondrial", "refseq_ac": [ { "id": "NP_001414183", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414183", "type": "external" } ], "gene_names_uniprotkb": "Mettl17", "gene_names_refseq": "Mett11d1; Mettl17; RGD1559895", "protein_names_uniprotkb": "Ribosome assembly protein METTL17, mitochondrial; Methyltransferase-like protein 17", "protein_names_refseq": "methyltransferase 11 domain containing 1; methyltransferase-like protein 17, mitochondrial", "tax_id": 10116, "disease": "", "pathway": " (rno:305845)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Mitochondrial ribosome (mitoribosome) assembly factor. Binds at the interface of the head and body domains of the mitochondrial small ribosomal subunit (mt-SSU), occluding the mRNA channel and preventing compaction of the head domain towards the body. Probable inactive methyltransferase: retains the characteristic folding and ability to bind S-adenosyl-L-methionine, but it probably lost its methyltransferase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0097177 mitochondrial ribosome binding;GO:1904047 S-adenosyl-L-methionine binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006412 translation;GO:0042274 ribosomal small subunit biogenesis;GO:0180026 mitochondrial small ribosomal subunit assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3Z930-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3Z951-1", "uniprot_id": [ { "id": "D3Z951_RAT", "url": "https://www.uniprot.org/uniprot/D3Z951", "type": "external" } ], "mass": 109721.0, "length": 994, "protein_name": "Rho GTPase-activating protein 11A", "gene_name": "Arhgap11a", "organism": "Rat", "refseq_name": "rho GTPase-activating protein 11A", "refseq_ac": [ { "id": "NP_001161996", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161996", "type": "external" } ], "gene_names_uniprotkb": "Arhgap11a", "gene_names_refseq": "Arhgap11a; RGD1309107", "protein_names_uniprotkb": "Rho GTPase-activating protein 11A; Rho-type GTPase-activating protein 11A", "protein_names_refseq": "rho GTPase-activating protein 11A", "tax_id": 10116, "disease": "", "pathway": " (rno:296060); (R-RNO-8980692)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0007165 signal transduction;GO:0043547 positive regulation of GTPase activity", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3Z951-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3Z9D0-1", "uniprot_id": [ { "id": "D3Z9D0_RAT", "url": "https://www.uniprot.org/uniprot/D3Z9D0", "type": "external" } ], "mass": 209510.0, "length": 1937, "protein_name": "KIAA1549 homolog", "gene_name": "Kiaa1549", "organism": "Rat", "refseq_name": "UPF0606 protein KIAA1549 homolog isoform X1", "refseq_ac": [ { "id": "XP_231616", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_231616", "type": "external" } ], "gene_names_uniprotkb": "Kiaa1549; RGD1306271", "gene_names_refseq": "Kiaa1549", "protein_names_uniprotkb": "KIAA1549 homolog", "protein_names_refseq": "UPF0606 protein KIAA1549 homolog isoform X1", "tax_id": 10116, "disease": "retinitis pigmentosa 86 (Disease Ontology:DOID:0112143)", "pathway": " (rno:312246)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "22673903;38843836", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0032391 photoreceptor connecting cilium", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "D3Z9D0-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0100000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3Z9J9-1", "uniprot_id": [ { "id": "D3Z9J9_RAT", "url": "https://www.uniprot.org/uniprot/D3Z9J9", "type": "external" } ], "mass": 47098.0, "length": 425, "protein_name": "Acylglycerol transacylase", "gene_name": "Pnpla3", "organism": "Rat", "refseq_name": "1-acylglycerol-3-phosphate O-acyltransferase PNPLA3", "refseq_ac": [ { "id": "NP_001269253", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269253", "type": "external" } ], "gene_names_uniprotkb": "Pnpla3", "gene_names_refseq": "Adpn; Pnpla3", "protein_names_uniprotkb": "Acylglycerol transacylase; 2.3.1.51; 3.1.1.3; 3.1.1.4; Adiponutrin; Calcium-independent phospholipase A2-epsilon; Lysophosphatidic acid acyltransferase; Patatin-like phospholipase domain-containing protein 3", "protein_names_refseq": "1-acylglycerol-3-phosphate O-acyltransferase PNPLA3; adiponutrin; patatin-like phospholipase domain containing 3; patatin-like phospholipase domain-containing protein 3", "tax_id": 10116, "disease": "Chanarin-Dorfman syndrome (Disease Ontology:DOID:0050729); acquired metabolic disease (Disease Ontology:DOID:0060158); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); hypothyroidism (Disease Ontology:DOID:1459); coronary artery disease (Disease Ontology:DOID:3393); liver cirrhosis (Disease Ontology:DOID:5082); hepatocellular carcinoma (Disease Ontology:DOID:684); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352); steatotic liver disease (Disease Ontology:DOID:9452); obesity (Disease Ontology:DOID:9970)", "pathway": " (rno:362972); (R-RNO-1482883)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "12565853;17372308;19619606;22673903;28433418;35908495", "class_list": "", "function": "Adiponutrin expression is highly regulated by feeding conditions in the different adipose tissue depots, but this regulation is impaired in obese rats., [RefSeq, PubMed]; Data suggest that adiponutrin could be involved in overall energy homeostasis, as is leptin., [RefSeq, PubMed]; Histone acetylation plays a role in the modulation of PNPLA3 levels in the liver exposed to binge ethanol drinking., [RefSeq, PubMed]; Inulin may prevent steatosis by suppressing cannabinoid receptor-1 and patatin-like phospholipase-3 expression in liver., [RefSeq, PubMed]; PNPLA3 mRNA expression is upregulated by tri-iodothyronine in adipocytes in vitro, in humans and rats, and in vivo in rat white adipose tissue., [RefSeq, PubMed]; Specifically catalyzes coenzyme A (CoA)-dependent acylation of 1-acyl-sn-glycerol 3-phosphate (2-lysophosphatidic acid/LPA) to generate phosphatidic acid (PA), an important metabolic intermediate and precursor for both triglycerides and glycerophospholipids. Does not esterify other lysophospholipids. Acyl donors are long chain (at least C16) fatty acyl-CoAs: arachidonoyl-CoA, linoleoyl-CoA, oleoyl-CoA and at a lesser extent palmitoyl-CoA. Additionally possesses low triacylglycerol lipase and CoA-independent acylglycerol transacylase activities and thus may play a role in acyl-chain remodeling of triglycerides. In vitro may express hydrolytic activity against glycerolipids triacylglycerol, diacylglycerol and monoacylglycerol, with a strong preference for oleic acid as the acyl moiety. However, the triacylglycerol hydrolase activity is controversial and may be very low. Possesses phospholipase A2 activity., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 11, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" }, { "id": "2.3.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.15", "type": "external" }, { "id": "3.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.-", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "3.1.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.23", "type": "external" }, { "id": "3.1.1.79", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.79", "type": "external" }, { "id": "3.1.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.6", "type": "external" }, { "id": "1.11.1.27", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.27", "type": "external" }, { "id": "2.3.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.23", "type": "external" }, { "id": "3.1.1.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.13", "type": "external" }, { "id": "2.3.1.67", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.67", "type": "external" }, { "id": "2.3.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.25", "type": "external" }, { "id": "3.1.1.116", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.116", "type": "external" }, { "id": "3.1.1.26", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.26", "type": "external" }, { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.1.1.34", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.34", "type": "external" }, { "id": "2.3.1.n7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.n7", "type": "external" } ], "go_molecular_function": "GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0042171 lysophosphatidic acid acyltransferase activity;GO:0004623 phospholipase A2 activity;GO:0036042 long-chain fatty acyl-CoA binding;GO:0004806 triacylglycerol lipase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005811 lipid droplet;GO:0016020 membrane", "go_biological_process": "GO:0006650 glycerophospholipid metabolic process;GO:0001676 long-chain fatty acid metabolic process;GO:0006654 phosphatidic acid biosynthetic process;GO:0032869 cellular response to insulin stimulus;GO:0050872 white fat cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "D3Z9J9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3Z9T8-1", "uniprot_id": [ { "id": "D3Z9T8_RAT", "url": "https://www.uniprot.org/uniprot/D3Z9T8", "type": "external" } ], "mass": 25715.0, "length": 225, "protein_name": "Phospholipid scramblase", "gene_name": "Plscr1l1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Plscr1l1", "gene_names_refseq": "", "protein_names_uniprotkb": "Phospholipid scramblase", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:102551265)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017128 phospholipid scramblase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0045089 positive regulation of innate immune response;GO:0070782 phosphatidylserine exposure on apoptotic cell surface", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3Z9T8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZA82-1", "uniprot_id": [ { "id": "D3ZA82_RAT", "url": "https://www.uniprot.org/uniprot/D3ZA82", "type": "external" } ], "mass": 119317.0, "length": 1048, "protein_name": "Maestro heat-like repeat family member 8", "gene_name": "Mroh8", "organism": "Rat", "refseq_name": "maestro heat-like repeat family member 8 isoform 1", "refseq_ac": [ { "id": "NP_001418728", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001418728", "type": "external" } ], "gene_names_uniprotkb": "Mroh8; LOC100360777", "gene_names_refseq": "Mroh8", "protein_names_uniprotkb": "Maestro heat-like repeat family member 8", "protein_names_refseq": "maestro heat-like repeat family member 8 isoform 1", "tax_id": 10116, "disease": "", "pathway": " (rno:100360777)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZA82-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZAB7-1", "uniprot_id": [ { "id": "D3ZAB7_RAT", "url": "https://www.uniprot.org/uniprot/D3ZAB7", "type": "external" } ], "mass": 34921.0, "length": 319, "protein_name": "Zinc finger protein 688", "gene_name": "Zfp688", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Zfp688", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger protein 688", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:102554302); (R-RNO-212436)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, 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Three CDX2-binding proteins were found in rat gastric tissue, and those proteins were identified to the homeobox protein Hox-D8, LIM homeobox protein 6, and SMC1L1 protein., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:1990837 sequence-specific double-stranded DNA binding;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0021877 forebrain neuron fate commitment;GO:0021799 cerebral cortex radially oriented cell migration;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030182 neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "D3ZDG6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZDJ5-1", "uniprot_id": [ { "id": "D3ZDJ5_RAT", "url": "https://www.uniprot.org/uniprot/D3ZDJ5", "type": "external" } ], "mass": 28591.0, "length": 245, "protein_name": "rRNA biogenesis protein RRP36", "gene_name": "Rrp36", "organism": "Rat", "refseq_name": "ribosomal RNA processing protein 36 homolog isoform 2", "refseq_ac": [ { "id": "NP_001386340", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386340", "type": "external" } ], "gene_names_uniprotkb": "Rrp36", "gene_names_refseq": "Rrp36", "protein_names_uniprotkb": "rRNA biogenesis protein RRP36", "protein_names_refseq": "rCG43434-like; ribosomal RNA processing 36 homolog; ribosomal RNA processing protein 36 homolog isoform 2; ribosomal RNA processing protein 36 homolog", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-6791226)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0030686 90S preribosome", "go_biological_process": "GO:0006364 rRNA processing;GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0042274 ribosomal small subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZDJ5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZE93-1", "uniprot_id": [ { "id": "D3ZE93_RAT", "url": "https://www.uniprot.org/uniprot/D3ZE93", "type": "external" } ], "mass": 29693.0, "length": 275, "protein_name": "CEA cell adhesion molecule 19", "gene_name": "Ceacam19", "organism": "Rat", "refseq_name": "carcinoembryonic antigen-related cell adhesion molecule 19 precursor", "refseq_ac": [ { "id": "NP_001185899", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185899", "type": "external" } ], "gene_names_uniprotkb": "Ceacam19", "gene_names_refseq": "Ceacam19", "protein_names_uniprotkb": "CEA cell adhesion molecule 19", "protein_names_refseq": "carcinoembryonic antigen-related cell adhesion molecule 19 precursor; carcinoembryonic antigen-related cell adhesion molecule 19", "tax_id": 10116, "disease": "", "pathway": " (rno:680640)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZE93-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZEC4-1", "uniprot_id": [ { "id": "D3ZEC4_RAT", "url": "https://www.uniprot.org/uniprot/D3ZEC4", "type": "external" } ], "mass": 33967.0, "length": 303, "protein_name": "Olfactory receptor", "gene_name": "Or1ad5", "organism": "Rat", "refseq_name": "olfactory receptor Olr1406", "refseq_ac": [ { "id": "NP_001000786", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000786", "type": "external" } ], "gene_names_uniprotkb": "Or1ad5", "gene_names_refseq": "Olr1406; Or1ad5", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1406; olfactory receptor Olr1406; olfactory receptor gene Olr1406", "tax_id": 10116, "disease": "", "pathway": " (rno:405064)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004984 olfactory receptor activity;GO:0038022 G protein-coupled olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZEC4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZEK5-1", "uniprot_id": [ { "id": "D3ZEK5_RAT", "url": "https://www.uniprot.org/uniprot/D3ZEK5", "type": "external" } ], "mass": 74513.0, "length": 660, "protein_name": "Heparan-sulfate 6-O-sulfotransferase", "gene_name": "Hs6st2", "organism": "Rat", "refseq_name": "heparan-sulfate 6-O-sulfotransferase 2", "refseq_ac": [ { "id": "NP_001178655", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178655", "type": "external" } ], "gene_names_uniprotkb": "Hs6st2", "gene_names_refseq": "Hs6st2; RGD1563872; RGD1564397", "protein_names_uniprotkb": "Heparan-sulfate 6-O-sulfotransferase; 2.8.2.-", "protein_names_refseq": "heparan-sulfate 6-O-sulfotransferase 2", "tax_id": 10116, "disease": "Paganini-Miozzo syndrome (Disease Ontology:DOID:0111843)", "pathway": " (rno:302489); (R-RNO-2022928)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "38843836", "class_list": "", "function": "6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.8.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.2.-", "type": "external" } ], "go_molecular_function": "GO:0017095 heparan sulfate 6-sulfotransferase activity;GO:0008146 sulfotransferase activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0016020 membrane", "go_biological_process": "GO:0015012 heparan sulfate proteoglycan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "D3ZEK5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZEL3-1", "uniprot_id": [ { "id": "D3ZEL3_RAT", "url": "https://www.uniprot.org/uniprot/D3ZEL3", "type": "external" } ], "mass": 36127.0, "length": 307, "protein_name": "Transmembrane and coiled-coil domains 5B", "gene_name": "Tmco5b", "organism": "Rat", "refseq_name": "transmembrane and coiled-coil domain-containing protein 5B isoform 1", "refseq_ac": [ { "id": "NP_001417594", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417594", "type": "external" } ], "gene_names_uniprotkb": "Tmco5b", "gene_names_refseq": "RGD1561237; 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Protects cells from ER stress-induced apoptosis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0051865 protein autoubiquitination;GO:1904294 positive regulation of ERAD pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZG84-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZGQ8-1", "uniprot_id": [ { "id": "D3ZGQ8_RAT", "url": "https://www.uniprot.org/uniprot/D3ZGQ8", "type": "external" } ], "mass": 162622.0, "length": 1448, "protein_name": "Remodeling and spacing factor 1", "gene_name": "Rsf1", "organism": "Rat", "refseq_name": "remodeling and spacing factor 1", "refseq_ac": [ { "id": "NP_001414397", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414397", "type": "external" } ], "gene_names_uniprotkb": "Rsf1", "gene_names_refseq": "Hbxap; Rsf1", "protein_names_uniprotkb": "Remodeling and spacing factor 1", "protein_names_refseq": "hepatitis B virus x associated protein; remodeling and spacing factor 1", "tax_id": 10116, "disease": "", "pathway": " (rno:308839); (R-RNO-606279)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042393 histone binding;GO:0140751 histone octamer slider activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0031213 RSF complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006355 regulation of DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZGQ8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZH95-1", "uniprot_id": [ { "id": "D3ZH95_RAT", "url": "https://www.uniprot.org/uniprot/D3ZH95", "type": "external" } ], "mass": 69104.0, "length": 622, "protein_name": "Retrotransposon Gag like 3", "gene_name": "Rtl3", "organism": "Rat", "refseq_name": "retrotransposon Gag-like protein 3", "refseq_ac": [ { "id": "NP_001388081", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001388081", "type": "external" } ], "gene_names_uniprotkb": "Rtl3", "gene_names_refseq": "RGD1564805; Rtl3; Zcchc5", "protein_names_uniprotkb": "Retrotransposon Gag like 3", "protein_names_refseq": "retrotransposon Gag-like protein 3; zinc finger CCHC domain-containing protein 5; zinc finger CCHC-type containing 5; zinc finger, CCHC domain containing 5", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003676 nucleic acid binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZH95-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZHU3-1", "uniprot_id": [ { "id": "D3ZHU3_RAT", "url": "https://www.uniprot.org/uniprot/D3ZHU3", "type": "external" } ], "mass": 45531.0, "length": 419, "protein_name": "MEF2-activating motif and SAP domain-containing transcriptional regulator", "gene_name": "Mamstr", "organism": "Rat", "refseq_name": "MEF2 activating motif and SAP domain containing transcriptional regulator", "refseq_ac": [ { "id": "NP_001419575", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001419575", "type": "external" } ], "gene_names_uniprotkb": "Mamstr", "gene_names_refseq": "Mamstr", "protein_names_uniprotkb": "MEF2-activating motif and SAP domain-containing transcriptional regulator; MEF2-activating SAP transcriptional regulatory protein", "protein_names_refseq": "MEF2 activating motif and SAP domain containing transcriptional regulator", "tax_id": 10116, "disease": "", "pathway": " (rno:691041)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcriptional coactivator. Stimulates the transcriptional activity of MEF2C. Stimulates MYOD1 activity in part via MEF2, resulting in an enhancement of skeletal muscle differentiation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0010831 positive regulation of myotube differentiation;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZHU3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZHX4-1", "uniprot_id": [ { "id": "D3ZHX4_RAT", "url": "https://www.uniprot.org/uniprot/D3ZHX4", "type": "external" } ], "mass": 68245.0, "length": 617, "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "Rmi1", "organism": "Rat", "refseq_name": "recQ-mediated genome instability protein 1", "refseq_ac": [ { "id": "NP_001387555", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001387555", "type": "external" } ], "gene_names_uniprotkb": "Rmi1", "gene_names_refseq": "RGD1310671; Rmi1", "protein_names_uniprotkb": "RecQ-mediated genome instability protein 1", "protein_names_refseq": "RMI1, RecQ mediated genome instability 1, homolog; recQ-mediated genome instability protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:306734); (R-RNO-5685938); (R-RNO-5685942); (R-RNO-5693537); (R-RNO-5693568); (R-RNO-5693579); (R-RNO-5693607); (R-RNO-5693616); (R-RNO-6804756); (R-RNO-69473)", "pathway_count": 10, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000166 nucleotide binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0016604 nuclear body;GO:0031422 RecQ family helicase-topoisomerase III complex", "go_biological_process": "GO:0000712 resolution of meiotic recombination intermediates;GO:0035264 multicellular organism growth;GO:0006260 DNA replication;GO:0042593 glucose homeostasis;GO:0009749 response to glucose", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZHX4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZI66-1", "uniprot_id": [ { "id": "D3ZI66_RAT", "url": "https://www.uniprot.org/uniprot/D3ZI66", "type": "external" } ], "mass": 42586.0, "length": 394, "protein_name": "Ring finger protein 149", "gene_name": "Rnf149", "organism": "Rat", "refseq_name": "E3 ubiquitin-protein ligase RNF149 precursor", "refseq_ac": [ { "id": "NP_001418215", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001418215", "type": "external" } ], "gene_names_uniprotkb": "Rnf149", "gene_names_refseq": "Rnf149", "protein_names_uniprotkb": "Ring finger protein 149", "protein_names_refseq": "E3 ubiquitin-protein ligase RNF149 precursor; E3 ubiquitin-protein ligase RNF149", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "35634494", "class_list": "", "function": "Role of the Ubiquitin Ligase RNF149 in the Development of Rat Neonatal Gonocytes. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0016020 membrane;GO:0005770 late endosome", "go_biological_process": "GO:0071466 cellular response to xenobiotic stimulus;GO:0031647 regulation of protein stability;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0043409 negative regulation of MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZI66-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZI75-1", "uniprot_id": [ { "id": "D3ZI75_RAT", "url": "https://www.uniprot.org/uniprot/D3ZI75", "type": "external" } ], "mass": 10875.0, "length": 99, "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2", "gene_name": "LOC120099907", "organism": "Rat", "refseq_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2-like", "refseq_ac": [ { "id": "XP_063137049", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063137049", "type": "external" } ], "gene_names_uniprotkb": "LOC120099907", "gene_names_refseq": "LOC120099907", "protein_names_uniprotkb": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2", "protein_names_refseq": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2-like", "tax_id": 10116, "disease": "nuclear type mitochondrial complex I deficiency 13 (Disease Ontology:DOID:0112076); Alzheimer's disease (Disease Ontology:DOID:10652)", "pathway": " (rno:120099907)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045271 respiratory chain complex I", "go_biological_process": "GO:0022904 respiratory electron transport chain", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZI75-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZI88-1", "uniprot_id": [ { "id": "D3ZI88_RAT", "url": "https://www.uniprot.org/uniprot/D3ZI88", "type": "external" } ], "mass": 133054.0, "length": 1164, "protein_name": "KIAA2012 homolog", "gene_name": "Kiaa2012", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Kiaa2012; RGD1562029", "gene_names_refseq": "", "protein_names_uniprotkb": "KIAA2012 homolog", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZI88-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZIE4-1", "uniprot_id": [ { "id": "FYB1_RAT", "url": "https://www.uniprot.org/uniprot/D3ZIE4", "type": "external" } ], "mass": 91412.0, "length": 830, "protein_name": "FYN-binding protein 1", "gene_name": "Fyb1", "organism": "Rat", "refseq_name": "FYN-binding protein 1 isoform X1", "refseq_ac": [ { "id": "XP_006232081", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006232081", "type": "external" } ], "gene_names_uniprotkb": "Fyb1; Fyb", "gene_names_refseq": "ADAP; Fyb1; Fyb; RGD1563421; SLAP-130; p120/p130", "protein_names_uniprotkb": "FYN-binding protein 1; ADAP; Adhesion and degranulation promoting adaptor protein; FYB-120/130; FYN-T-binding protein; SLAP-130; SLP-76-associated phosphoprotein; p120/p130", "protein_names_refseq": "FYN-binding protein 1 isoform X1", "tax_id": 10116, "disease": "thrombocytopenia (Disease Ontology:DOID:1588)", "pathway": " (rno:499537); (R-RNO-202433); (R-RNO-391160)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "12681493;22673903", "class_list": "", "function": "Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells (By similarity). May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton (By similarity). Modulates the expression of IL2 (By similarity). Involved in platelet activation (By similarity). Prevents the degradation of SKAP1 and SKAP2 (By similarity). May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells (PubMed:12681493)., [UniProtKB, UniProtKB, PubMed, UniProtKB]; Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton. Modulates the expression of IL2. Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008289 lipid binding;GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0032991 protein-containing complex;GO:0070161 anchoring junction", "go_biological_process": "GO:0007229 integrin-mediated signaling pathway;GO:0072659 protein localization to plasma membrane;GO:0050852 T cell receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZIE4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZIM9-1", "uniprot_id": [ { "id": "D3ZIM9_RAT", "url": "https://www.uniprot.org/uniprot/D3ZIM9", "type": "external" } ], "mass": 18314.0, "length": 160, "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "ENSRNOG00000064328", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ENSRNOG00000064328", "gene_names_refseq": "", "protein_names_uniprotkb": "Large ribosomal subunit protein eL21; 60S ribosomal protein L21", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZIM9-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZJ07-1", "uniprot_id": [ { "id": "D3ZJ07_RAT", "url": "https://www.uniprot.org/uniprot/D3ZJ07", "type": "external" } ], "mass": 65789.0, "length": 602, "protein_name": "T-box transcription factor 15", "gene_name": "Tbx15", "organism": "Rat", "refseq_name": "T-box transcription factor TBX15", "refseq_ac": [ { "id": "NP_001382004", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382004", "type": "external" } ], "gene_names_uniprotkb": "Tbx15", "gene_names_refseq": "Tbx15", "protein_names_uniprotkb": "T-box transcription factor 15", "protein_names_refseq": "T-box 15; T-box transcription factor TBX15", "tax_id": 10116, "disease": "", "pathway": " (rno:295315)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:1990837 sequence-specific double-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0090571 RNA polymerase II transcription repressor complex", "go_biological_process": "GO:0001708 cell fate specification;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZJ07-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZJ32-1", "uniprot_id": [ { "id": "D3ZJ32_RAT", "url": "https://www.uniprot.org/uniprot/D3ZJ32", "type": "external" } ], "mass": 94100.0, "length": 845, "protein_name": "Extended synaptotagmin-2", "gene_name": "Esyt2", "organism": "Rat", "refseq_name": "extended synaptotagmin-2", "refseq_ac": [ { "id": "NP_001258098", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258098", "type": "external" } ], "gene_names_uniprotkb": "Esyt2", "gene_names_refseq": "Esyt2; RGD1565705", "protein_names_uniprotkb": "Extended synaptotagmin-2", "protein_names_refseq": "extended synaptotagmin protein 2; extended synaptotagmin-2; extended synaptotagmin-like protein 2", "tax_id": 10116, "disease": "", "pathway": " (rno:299488); (R-RNO-9845576)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "19893752;22673903", "class_list": "", "function": "Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding; this occurs most likely via the AP-2 complex. Promotes the localization of SACM1L at endoplasmic reticulum-plasma membrane contact sites (EPCS)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Visual signals derived from the rat ChR2-expressing retinal ganglion cells under the control of a mouse Thy-1.2 promotor are reinterpreted by the brain to form behavior-related vision Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0005509 calcium ion binding;GO:0005544 calcium-dependent phospholipid binding;GO:0008429 phosphatidylethanolamine binding;GO:0031210 phosphatidylcholine binding", "go_cellular_component": "GO:0044232 organelle membrane contact site;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane;GO:0009898 cytoplasmic side of plasma membrane;GO:0140268 endoplasmic reticulum-plasma membrane contact site", "go_biological_process": "GO:0006869 lipid transport;GO:0006897 endocytosis;GO:0061817 endoplasmic reticulum-plasma membrane tethering", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZJ32-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZJ51-1", "uniprot_id": [ { "id": "D3ZJ51_RAT", "url": "https://www.uniprot.org/uniprot/D3ZJ51", "type": "external" } ], "mass": 104636.0, "length": 927, "protein_name": "PHD finger protein 8 like", "gene_name": "Phf8l", "organism": "Rat", "refseq_name": "uncharacterized protein LOC299557", "refseq_ac": [ { "id": "NP_001100235", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100235", "type": "external" } ], "gene_names_uniprotkb": "Phf8l; RGD1310212", "gene_names_refseq": "Phf8l; RGD1310212", "protein_names_uniprotkb": "PHD finger protein 8 like", "protein_names_refseq": "uncharacterized protein LOC299557", "tax_id": 10116, "disease": "syndromic X-linked intellectual disability (Disease Ontology:DOID:0060309); syndromic X-linked intellectual disability Siderius type (Disease Ontology:DOID:0060812); prostate cancer (Disease Ontology:DOID:10283)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0051213 dioxygenase activity;GO:0003712 transcription coregulator activity;GO:0032452 histone demethylase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZJ51-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZJC1-1", "uniprot_id": [ { "id": "D3ZJC1_RAT", "url": "https://www.uniprot.org/uniprot/D3ZJC1", "type": "external" } ], "mass": 29655.0, "length": 277, "protein_name": "CIMAP1 family member D", "gene_name": "Cimap1d", "organism": "Rat", "refseq_name": "protein CIMAP1D", "refseq_ac": [ { "id": "NP_001178706", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178706", "type": "external" } ], "gene_names_uniprotkb": "Cimap1d; 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Morc; RGD1565610", "protein_names_uniprotkb": "MORC family CW-type zinc finger protein 1", "protein_names_refseq": "MORC family CW-type zinc finger protein 1; microrchidia 1", "tax_id": 10116, "disease": "melancholic depression (Disease Ontology:DOID:1595)", "pathway": " (rno:360712)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29393594;34331083", "class_list": "", "function": "Morc1 as a potential new target gene in mood regulation: when and where to find in the brain., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0007283 spermatogenesis;GO:0010629 negative regulation of gene expression;GO:0030154 cell differentiation;GO:0001662 behavioral fear response;GO:0031047 regulatory ncRNA-mediated gene silencing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZKF3-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZKL5-1", "uniprot_id": [ { "id": "D3ZKL5_RAT", "url": "https://www.uniprot.org/uniprot/D3ZKL5", "type": "external" } ], "mass": 35095.0, "length": 310, "protein_name": "Olfactory receptor", "gene_name": "Or5m9", "organism": "Rat", "refseq_name": "olfactory receptor Olr475", "refseq_ac": [ { "id": "NP_001000686", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000686", "type": "external" } ], "gene_names_uniprotkb": "Or5m9", "gene_names_refseq": "Olr475; Or5m9", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 475; olfactory receptor Olr475; olfactory receptor gene Olr475", "tax_id": 10116, "disease": "", "pathway": " (rno:404891)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZKL5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZL21-1", "uniprot_id": [ { "id": "D3ZL21_RAT", "url": "https://www.uniprot.org/uniprot/D3ZL21", "type": "external" } ], "mass": 27615.0, "length": 246, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Tp53rka", "organism": "Rat", "refseq_name": "TP53-regulating kinase (p53-related protein kinase) (Nori-2)", "refseq_ac": [ { "id": "NP_001386770", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386770", "type": "external" } ], "gene_names_uniprotkb": "Tp53rka; LOC685619; Trp53rka", "gene_names_refseq": "Tp53rka; Trp53rka", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1; Nori-2; TP53-regulating kinase; p53-related protein kinase", "protein_names_refseq": "EKC/KEOPS complex subunit TP53RK; TP53-regulating kinase (p53-related protein kinase) (Nori-2); TP53-regulating kinase; rCG32187-like; transformation related protein 53 regulating kinase A; tumor protein p53 regulating kinase A", "tax_id": 10116, "disease": "Galloway-Mowat syndrome 4 (Disease Ontology:DOID:0080246)", "pathway": " (rno:685619); (R-RNO-6804756)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TP53RK has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit OSGEP. Atypical protein kinase that phosphorylates 'Ser-15' of p53/TP53 protein and may therefore participate in its activation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, 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}, { "id": "2.7.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.34", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" }, { "id": "2.7.11.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.19", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": 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Or8a1", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1195; olfactory receptor Olr1195; olfactory receptor gene Olr1195", "tax_id": 10116, "disease": "", "pathway": " (rno:405971)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZMV7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZMY7-1", "uniprot_id": [ { "id": "5NTC_RAT", "url": "https://www.uniprot.org/uniprot/D3ZMY7", "type": "external" } ], "mass": 64866.0, "length": 560, "protein_name": "Cytosolic purine 5'-nucleotidase", "gene_name": "Nt5c2", "organism": "Rat", "refseq_name": "cytosolic purine 5'-nucleotidase", "refseq_ac": [ { "id": "NP_001388640", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001388640", "type": "external" } ], "gene_names_uniprotkb": "Nt5c2", "gene_names_refseq": "Nt5c2", "protein_names_uniprotkb": "Cytosolic purine 5'-nucleotidase; 2.7.1.77; 3.1.3.5; 3.1.3.99; Cytosolic nucleoside phosphotransferase 5'N", "protein_names_refseq": "cytosolic nucleoside phosphotransferase 5'N; cytosolic purine 5'-nucleotidase", "tax_id": 10116, "disease": "hereditary spastic paraplegia 45 (Disease Ontology:DOID:0110797); obesity (Disease Ontology:DOID:9970)", "pathway": " (rno:100363253); (R-RNO-2161541); (R-RNO-74259); (R-RNO-9755088)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "6260203", "class_list": "", "function": "Broad specificity cytosolic 5'-nucleotidase that catalyzes the dephosphorylation of 6-hydroxypurine nucleoside 5'-monophosphates (PubMed:6260203). In addition, possesses a phosphotransferase activity by which it can transfer a phosphate from a donor nucleoside monophosphate to an acceptor nucleoside, preferably inosine, deoxyinosine and guanosine (By similarity). Has the highest activities for IMP and GMP followed by dIMP, dGMP and XMP (PubMed:6260203). Could also catalyze the transfer of phosphates from pyrimidine monophosphates but with lower efficiency (By similarity). Through these activities regulates the purine nucleoside/nucleotide pools within the cell (PubMed:6260203)., [UniProtKB, PubMed, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.5", "type": "external" }, { "id": "2.7.1.77", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.77", "type": "external" }, { "id": "3.1.3.99", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.99", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.91", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.91", "type": "external" }, { "id": "3.1.3.89", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.89", "type": "external" }, { "id": "3.1.3.35", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.35", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.1.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.1", "type": "external" }, { "id": "3.6.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.9", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0008253 5'-nucleotidase activity;GO:0050146 nucleoside phosphotransferase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0050689 negative regulation of defense response to virus by host;GO:0046054 dGMP metabolic process;GO:0046037 GMP metabolic process;GO:0046040 IMP metabolic process;GO:0046085 adenosine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZMY7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZN03-1", "uniprot_id": [ { "id": "D3ZN03_RAT", "url": "https://www.uniprot.org/uniprot/D3ZN03", "type": "external" } ], "mass": 11762.0, "length": 115, "protein_name": "Large ribosomal subunit protein P2", "gene_name": "Rplp2l3", "organism": "Rat", "refseq_name": "large ribosomal subunit protein P2-like", "refseq_ac": [ { "id": "XP_038948670", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038948670", "type": "external" } ], "gene_names_uniprotkb": "Rplp2l3; LOC100362751", "gene_names_refseq": "Rplp2l3", "protein_names_uniprotkb": "Large ribosomal subunit protein P2; 60S acidic ribosomal protein P2", "protein_names_refseq": "large ribosomal subunit protein P2-like", "tax_id": 10116, "disease": "", "pathway": " (rno:100362751)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays an important role in the elongation step of protein synthesis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0002182 cytoplasmic translational elongation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZN03-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZN41-1", "uniprot_id": [ { "id": "D3ZN41_RAT", "url": "https://www.uniprot.org/uniprot/D3ZN41", "type": "external" } ], "mass": 158841.0, "length": 1417, "protein_name": "Phospholipid-transporting ATPase", "gene_name": "Atp10d", "organism": "Rat", "refseq_name": "phospholipid-transporting ATPase VD", "refseq_ac": [ { "id": "NP_001414735", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414735", "type": "external" } ], "gene_names_uniprotkb": "Atp10d", "gene_names_refseq": "Atp10d", "protein_names_uniprotkb": "Phospholipid-transporting ATPase; 7.6.2.1", "protein_names_refseq": "ATPase, class V, type 10D; phospholipid-transporting ATPase VD; probable phospholipid-transporting ATPase VD", "tax_id": 10116, "disease": "progressive familial intrahepatic cholestasis (Disease Ontology:DOID:0070221)", "pathway": " (rno:360932); (R-RNO-936837)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "7.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.1", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0140326 ATPase-coupled intramembrane lipid transporter activity;GO:0140351 glycosylceramide flippase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane;GO:1990531 phospholipid-translocating ATPase complex", "go_biological_process": "GO:0045332 phospholipid translocation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZN41-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZNC0-1", "uniprot_id": [ { "id": "D3ZNC0_RAT", "url": "https://www.uniprot.org/uniprot/D3ZNC0", "type": "external" } ], "mass": 49064.0, "length": 455, "protein_name": "OTU domain-containing protein 1", "gene_name": "Otud1", "organism": "Rat", "refseq_name": "OTU domain-containing protein 1", "refseq_ac": [ { "id": "NP_001387701", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001387701", "type": "external" } ], "gene_names_uniprotkb": "Otud1", "gene_names_refseq": "Otud1; RGD1563344", "protein_names_uniprotkb": "OTU domain-containing protein 1; 3.4.19.12", "protein_names_refseq": "OTU domain containing 1; OTU domain-containing protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:498803); (R-RNO-5357786); (R-RNO-5357905); (R-RNO-5357956)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Deubiquitinating enzyme that specifically hydrolyzes 'Lys-63'-linked polyubiquitin to monoubiquitin. Required for the stability and translation of a subset mRNAs with a high abundance of rare codons by mediating deubiquitination of 40S ribosomal protein RPS10/eS10, thereby antagonizing ZNF598-mediated 40S ubiquitination. The abundance of rare codons in mRNAs can limit the translation rate and can lead to ribosome collisions that trigger activation of ribosome quality control (RQC) pathway by ZNF598. OTUD1-mediated deubiquitination prevents activation of the RQC and subsequent dissociation of ribosomes and stimulates formation of polysomes and translation., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" } ], "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "", "go_biological_process": "GO:0006508 proteolysis;GO:0070536 protein K63-linked deubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZNC0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZNC9-1", "uniprot_id": [ { "id": "D3ZNC9_RAT", "url": "https://www.uniprot.org/uniprot/D3ZNC9", "type": "external" } ], "mass": 45265.0, "length": 409, "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "Marchf4", "organism": "Rat", "refseq_name": "E3 ubiquitin-protein ligase MARCHF4", "refseq_ac": [ { "id": "NP_001414713", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414713", "type": "external" } ], "gene_names_uniprotkb": "Marchf4; March4", "gene_names_refseq": "March4; Marchf4", "protein_names_uniprotkb": "RING-type E3 ubiquitin transferase; 2.3.2.27", "protein_names_refseq": "E3 ubiquitin-protein ligase MARCH4; E3 ubiquitin-protein ligase MARCHF4; membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase", "tax_id": 10116, "disease": "", "pathway": " (rno:367295)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005795 Golgi stack;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZNC9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZNI3-1", "uniprot_id": [ { "id": "D3ZNI3_RAT", "url": "https://www.uniprot.org/uniprot/D3ZNI3", "type": "external" } ], "mass": 209606.0, "length": 1877, "protein_name": "Protein RRP5 homolog", "gene_name": "Pdcd11", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Pdcd11", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein RRP5 homolog; Programmed cell death protein 11", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-6791226)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0051059 NF-kappaB binding;GO:0003676 nucleic acid binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005829 cytosol;GO:0032040 small-subunit processome", "go_biological_process": "GO:0006364 rRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZNI3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZNP4-1", "uniprot_id": [ { "id": "D3ZNP4_RAT", "url": "https://www.uniprot.org/uniprot/D3ZNP4", "type": "external" } ], "mass": 20241.0, "length": 180, "protein_name": "PABIR family member 3", "gene_name": "Pabir3", "organism": "Rat", "refseq_name": "PABIR family member 3 isoform 1", "refseq_ac": [ { "id": "NP_001420045", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001420045", "type": "external" } ], "gene_names_uniprotkb": "Pabir3; Fam122c", "gene_names_refseq": "Fam122c; Pabir3", "protein_names_uniprotkb": "PABIR family member 3", "protein_names_refseq": "PABIR family member 1; PABIR family member 3 isoform 1; family with sequence similarity 122, member C; family with sequence similarity 122C; protein FAM122A-like", "tax_id": 10116, "disease": "", "pathway": " (rno:685701)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004865 protein serine/threonine phosphatase inhibitor activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZNP4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZNS6-1", "uniprot_id": [ { "id": "D3ZNS6_RAT", "url": "https://www.uniprot.org/uniprot/D3ZNS6", "type": "external" } ], "mass": 167398.0, "length": 1488, "protein_name": "Pleckstrin homology domain-containing family H member 2", "gene_name": "Plekhh2", "organism": "Rat", "refseq_name": "pleckstrin homology domain-containing family H member 2", "refseq_ac": [ { "id": "NP_001178699", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178699", "type": "external" } ], "gene_names_uniprotkb": "Plekhh2", "gene_names_refseq": "Plekhh2; RGD1304935", "protein_names_uniprotkb": "Pleckstrin homology domain-containing family H member 2", "protein_names_refseq": "pleckstrin homology domain containing, family H (with MyTH4 domain) member 2; pleckstrin homology domain-containing family H member 2", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "16641100;22673903", "class_list": "", "function": "In the kidney glomerulus may play a role in linking podocyte foot processes to the glomerular basement membrane. May be involved in stabilization of F-actin by attenuating its depolymerization. Can recruit TGFB1I1 from focal adhesions to podocyte lamellipodia., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0030027 lamellipodium;GO:0030864 cortical actin cytoskeleton", "go_biological_process": "GO:0030835 negative regulation of actin filament depolymerization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZNS6-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZP59-1", "uniprot_id": [ { "id": "D3ZP59_RAT", "url": "https://www.uniprot.org/uniprot/D3ZP59", "type": "external" } ], "mass": 27848.0, "length": 248, "protein_name": "Nucleophosmin", "gene_name": "AABR07055527.1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "AABR07055527.1", "gene_names_refseq": "", "protein_names_uniprotkb": "Nucleophosmin", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0003723 RNA binding;GO:0042802 identical protein binding;GO:0042393 histone binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0010824 regulation of centrosome duplication;GO:0000055 ribosomal large subunit export from nucleus;GO:0006338 chromatin remodeling;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0042273 ribosomal large subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZP59-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZP96-1", "uniprot_id": [ { "id": "D3ZP96_RAT", "url": "https://www.uniprot.org/uniprot/D3ZP96", "type": "external" } ], "mass": 102144.0, "length": 905, "protein_name": "DNA replication licensing factor MCM2", "gene_name": "Mcm2", "organism": "Rat", "refseq_name": "DNA replication licensing factor MCM2", "refseq_ac": [ { "id": "NP_001101343", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101343", "type": "external" } ], "gene_names_uniprotkb": "Mcm2", "gene_names_refseq": "Mcm2", "protein_names_uniprotkb": "DNA replication licensing factor MCM2; 3.6.4.12; DNA replication licensing factor mcm2; Minichromosome maintenance protein 2 homolog; Nuclear protein BM28", "protein_names_refseq": "DNA replication licensing factor MCM2; minichromosome maintenance deficient 2 mitotin", "tax_id": 10116, "disease": "autosomal dominant nonsyndromic deafness 70 (Disease Ontology:DOID:0110592); Alzheimer's disease (Disease Ontology:DOID:10652)", "pathway": " (rno:312538); (R-RNO-176187); (R-RNO-68867); (R-RNO-68949); (R-RNO-68962)", "pathway_count": 5, "publication_count": 2, "publication_id_list": "22673903;29393594", "class_list": "", "function": "Acts as a component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division. Plays a role in terminally differentiated hair cells development of the cochlea and induces cells apoptosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.-", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "7.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.9.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.9.1.1", "type": "external" }, { "id": "6.1.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.12", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" } ], "go_molecular_function": "GO:0003688 DNA replication origin binding;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0019899 enzyme binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0000785 chromatin;GO:0005664 nuclear origin of replication recognition complex", "go_biological_process": "GO:0006915 apoptotic process;GO:0006260 DNA replication;GO:0006334 nucleosome assembly;GO:0071353 cellular response to interleukin-4;GO:0006270 DNA replication initiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZP96-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZPC3-1", "uniprot_id": [ { "id": "D3ZPC3_RAT", "url": "https://www.uniprot.org/uniprot/D3ZPC3", "type": "external" } ], "mass": 30795.0, "length": 279, "protein_name": "TLC domain containing 2", "gene_name": "Tlcd2", "organism": "Rat", "refseq_name": "TLC domain-containing protein 2", "refseq_ac": [ { "id": "NP_001385776", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385776", "type": "external" } ], "gene_names_uniprotkb": "Tlcd2", "gene_names_refseq": "RGD1562631; Tlcd2", "protein_names_uniprotkb": "TLC domain containing 2", "protein_names_refseq": "TLC domain-containing protein 2", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007009 plasma membrane organization;GO:0055091 phospholipid homeostasis;GO:0071709 membrane assembly;GO:0097035 regulation of membrane lipid distribution", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZPC3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZPL5-1", "uniprot_id": [ { "id": "D3ZPL5_RAT", "url": "https://www.uniprot.org/uniprot/D3ZPL5", "type": "external" } ], "mass": 30122.0, "length": 266, "protein_name": "60S ribosomal protein L7a", "gene_name": "AABR07007121.1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "AABR07007121.1", "gene_names_refseq": "", "protein_names_uniprotkb": "60S ribosomal protein L7a", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the ribosome., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0000470 maturation of LSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZPL5-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZPN7-1", "uniprot_id": [ { "id": "D3ZPN7_RAT", "url": "https://www.uniprot.org/uniprot/D3ZPN7", "type": "external" } ], "mass": 18678.0, "length": 160, "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC134480579", "organism": "Rat", "refseq_name": "large ribosomal subunit protein eL21-like", "refseq_ac": [ { "id": "XP_063124197", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063124197", "type": "external" } ], "gene_names_uniprotkb": "LOC134480579", "gene_names_refseq": "LOC134480579", "protein_names_uniprotkb": "Large ribosomal subunit protein eL21; 60S ribosomal protein L21", "protein_names_refseq": "large ribosomal subunit protein eL21-like", "tax_id": 10116, "disease": "", "pathway": " (rno:134480579); (R-RNO-156827); (R-RNO-1799339); (R-RNO-6791226); (R-RNO-72689); (R-RNO-72706); (R-RNO-975956); (R-RNO-975957); (R-RNO-9954709); (R-RNO-9954714); (R-RNO-9954716)", "pathway_count": 11, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZPN7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZPP0-1", "uniprot_id": [ { "id": "D3ZPP0_RAT", "url": "https://www.uniprot.org/uniprot/D3ZPP0", "type": "external" } ], "mass": 68283.0, "length": 619, "protein_name": "Zinc finger protein 668", "gene_name": "Zfp668", "organism": "Rat", "refseq_name": "zinc finger protein 668 isoform 1", "refseq_ac": [ { "id": "NP_001425143", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001425143", "type": "external" } ], "gene_names_uniprotkb": "Zfp668", "gene_names_refseq": "RGD1308623; Zfp668; Znf668", "protein_names_uniprotkb": "Zinc finger protein 668", "protein_names_refseq": "zinc finger protein 668 isoform 1", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-212436)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "May be involved in transcriptional regulation. May play a role in DNA repair process., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000976 transcription cis-regulatory region binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006281 DNA repair;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZPP0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZQ30-1", "uniprot_id": [ { "id": "D3ZQ30_RAT", "url": "https://www.uniprot.org/uniprot/D3ZQ30", "type": "external" } ], "mass": 93659.0, "length": 840, "protein_name": "Telomere length regulation protein TEL2 homolog", "gene_name": "Telo2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Telo2", "gene_names_refseq": "", "protein_names_uniprotkb": "Telomere length regulation protein TEL2 homolog", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:302986)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. May be involved in telomere length regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0019901 protein kinase binding;GO:0019900 kinase binding;GO:0042162 telomeric DNA binding;GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016604 nuclear body;GO:0110078 TTT Hsp90 cochaperone complex", "go_biological_process": "GO:0051083 'de novo' cotranslational protein folding;GO:0050821 protein stabilization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZQ30-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZQ38-1", "uniprot_id": [ { "id": "D3ZQ38_RAT", "url": "https://www.uniprot.org/uniprot/D3ZQ38", "type": "external" } ], "mass": 23607.0, "length": 210, "protein_name": "TBC/LysM-associated domain containing 2", "gene_name": "Tldc2", "organism": "Rat", "refseq_name": "TLD domain-containing protein 2 isoform X2", "refseq_ac": [ { "id": "XP_017447757", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017447757", "type": "external" } ], "gene_names_uniprotkb": "Tldc2; LOC100364430", "gene_names_refseq": "Tldc2", "protein_names_uniprotkb": "TBC/LysM-associated domain containing 2", "protein_names_refseq": "TLD domain-containing protein 2 isoform X2", "tax_id": 10116, "disease": "cerebellar hyplasia/atrophy, epilepsy, and global developmental delay (Disease Ontology:DOID:0070339)", "pathway": " (rno:502689)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006979 response to oxidative stress;GO:1900408 negative regulation of cellular response to oxidative stress", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZQ38-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZQ68-1", "uniprot_id": [ { "id": "D3ZQ68_RAT", "url": "https://www.uniprot.org/uniprot/D3ZQ68", "type": "external" } ], "mass": 77451.0, "length": 680, "protein_name": "Zinc finger protein 263", "gene_name": "Zfp263", "organism": "Rat", "refseq_name": "zinc finger protein 263", "refseq_ac": [ { "id": "NP_001386347", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386347", "type": "external" } ], "gene_names_uniprotkb": "Zfp263", "gene_names_refseq": "Zfp263", "protein_names_uniprotkb": "Zinc finger protein 263; Zinc finger protein FPM315; Zinc finger protein with KRAB and SCAN domains 12", "protein_names_refseq": "zinc finger protein 263", "tax_id": 10116, "disease": "", "pathway": " (rno:287076); (R-RNO-212436)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Transcription factor that binds to the consensus sequence 5'-TCCTCCC-3' and acts as a transcriptional repressor. Binds to the promoter region of SIX3 and recruits other proteins involved in chromatin modification and transcriptional corepression, resulting in methylation of the promoter and transcriptional repression. Acts as a transcriptional repressor of HS3ST1 and HS3ST3A1 via binding to gene promoter regions., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000976 transcription cis-regulatory region binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZQ68-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZQD9-1", "uniprot_id": [ { "id": "D3ZQD9_RAT", "url": "https://www.uniprot.org/uniprot/D3ZQD9", "type": "external" } ], "mass": 18710.0, "length": 158, "protein_name": "Developmental pluripotency-associated protein 3-like", "gene_name": "LOC120096627", "organism": "Rat", "refseq_name": "developmental pluripotency-associated protein 3-like", "refseq_ac": [ { "id": "XP_063129850", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063129850", "type": "external" } ], "gene_names_uniprotkb": "LOC120096627", "gene_names_refseq": "LOC120096627", "protein_names_uniprotkb": "Developmental pluripotency-associated protein 3-like", "protein_names_refseq": "developmental pluripotency-associated protein 3-like", "tax_id": 10116, "disease": "", "pathway": " (rno:120096627)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0044726 epigenetic programing of female pronucleus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZQD9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZQE6-1", "uniprot_id": [ { "id": "D3ZQE6_RAT", "url": "https://www.uniprot.org/uniprot/D3ZQE6", "type": "external" } ], "mass": 34838.0, "length": 309, "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "Or8b101c", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Or8b101c; Olfr887; Olr1217", "gene_names_refseq": "", "protein_names_uniprotkb": "G-protein coupled receptors family 1 profile domain-containing protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZQE6-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZQH3-1", "uniprot_id": [ { "id": "D3ZQH3_RAT", "url": "https://www.uniprot.org/uniprot/D3ZQH3", "type": "external" } ], "mass": 60712.0, "length": 574, "protein_name": "Scavenger receptor cysteine rich family member with 4 domains", "gene_name": "Ssc4d", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ssc4d; Srcrb4d", "gene_names_refseq": "", "protein_names_uniprotkb": "Scavenger receptor cysteine rich family member with 4 domains", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:304401)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005044 scavenger receptor activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZQH3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZQK8-1", "uniprot_id": [ { "id": "D3ZQK8_RAT", "url": "https://www.uniprot.org/uniprot/D3ZQK8", "type": "external" } ], "mass": 196838.0, "length": 1719, "protein_name": "Lymphocyte antigen 75", "gene_name": "Ly75", "organism": "Rat", "refseq_name": "lymphocyte antigen 75 precursor", "refseq_ac": [ { "id": "NP_001414075", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414075", "type": "external" } ], "gene_names_uniprotkb": "Ly75", "gene_names_refseq": "Ly75; RGD1565962", "protein_names_uniprotkb": "Lymphocyte antigen 75; DEC-205", "protein_names_refseq": "lymphocyte antigen 75 precursor", "tax_id": 10116, "disease": "", "pathway": " (rno:499800)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "29393594", "class_list": "", "function": "Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment. Causes reduced proliferation of B lymphocytes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0030246 carbohydrate binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0006898 receptor-mediated endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZQK8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZRG8-1", "uniprot_id": [ { "id": "D3ZRG8_RAT", "url": "https://www.uniprot.org/uniprot/D3ZRG8", "type": "external" } ], "mass": 175130.0, "length": 1639, "protein_name": "Peroxisome proliferator-activated receptor gamma coactivator-related protein 1", "gene_name": "Pprc1", "organism": "Rat", "refseq_name": "peroxisome proliferator-activated receptor gamma coactivator-related protein 1 isoform 1", "refseq_ac": [ { "id": "NP_001424478", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001424478", "type": "external" } ], "gene_names_uniprotkb": "Pprc1", "gene_names_refseq": "Pprc1", "protein_names_uniprotkb": "Peroxisome proliferator-activated receptor gamma coactivator-related protein 1; PGC-1-related coactivator", "protein_names_refseq": "peroxisome proliferative activated receptor, gamma, coactivator-related 1; peroxisome proliferator-activated receptor gamma coactivator-related protein 1 isoform 1; peroxisome proliferator-activated receptor gamma coactivator-related protein 1; peroxisome proliferator-activated receptor gamma, coactivator-related 1", "tax_id": 10116, "disease": "Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a coactivator during transcriptional activation of nuclear genes related to mitochondrial biogenesis and cell growth. Involved in the transcription coactivation of CREB and NRF1 target genes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0003723 RNA binding;GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0097009 energy homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZRG8-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZRM0-1", "uniprot_id": [ { "id": "D3ZRM0_RAT", "url": "https://www.uniprot.org/uniprot/D3ZRM0", "type": "external" } ], "mass": 128730.0, "length": 1137, "protein_name": "Serine/threonine/tyrosine interacting like 2", "gene_name": "Styxl2", "organism": "Rat", "refseq_name": "serine/threonine/tyrosine-interacting-like protein 2", "refseq_ac": [ { "id": "NP_001178858", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178858", "type": "external" } ], "gene_names_uniprotkb": "Styxl2; 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Tigit", "protein_names_uniprotkb": "T-cell immunoreceptor with Ig and ITIM domains; V-set and transmembrane domain-containing protein 3", "protein_names_refseq": "T cell immunoreceptor with Ig and ITIM domains precursor", "tax_id": 10116, "disease": "", "pathway": " (rno:363784)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "21416464", "class_list": "", "function": "Animals deficient in Vstm3 are more sensitive to autoimmune challenges indicating that this new member of the CD28 family is an important regulator of T-cell responses, [RefSeq, PubMed]; Inhibitory receptor that plays a role in the modulation of immune responses. Suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. Upon binding to its ligands PVR/CD155 or NECTIN2/CD112, which are expressed on antigen-presenting cells, sends inhibitory signals to the T-cell or NK cell. Mechanistically, interaction with ligand leads to phosphorylation of the cytoplasmic tail by Src family tyrosine kinases such as FYN or LCK, allowing subsequent binding to adapter GRB2 and SHIP1/INPP5D. In turn, inhibits PI3K and MAPK signaling cascades. In addition, associates with beta-arrestin-2/ARRB2 to recruit SHIP1/INPP5D that suppresses autoubiquitination of TRAF6 and subsequently inhibits NF-kappa-B signaling pathway. Also acts as a receptor for NECTIN4 to inhibit NK cell cytotoxicity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0042802 identical protein binding;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0032695 negative regulation of interleukin-12 production;GO:0045953 negative regulation of natural killer cell mediated cytotoxicity;GO:0032733 positive regulation of interleukin-10 production;GO:0050868 negative regulation of T cell activation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZTQ2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZTT0-1", "uniprot_id": [ { "id": "D3ZTT0_RAT", "url": "https://www.uniprot.org/uniprot/D3ZTT0", "type": "external" } ], "mass": 40904.0, "length": 357, "protein_name": "Double homeobox 4", "gene_name": "Dux4", "organism": "Rat", "refseq_name": "double homeobox 4", "refseq_ac": [ { "id": "NP_001419931", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001419931", "type": "external" } ], "gene_names_uniprotkb": "Dux4; Duxbl1", "gene_names_refseq": "Dux4; Duxbl1; Duxbl; RGD1311053", "protein_names_uniprotkb": "Double homeobox 4", "protein_names_refseq": "double homeobox 4; double homeobox B-like 1; double homeobox protein 4C-like; double homeobox protein B", "tax_id": 10116, "disease": "", "pathway": " (rno:306226)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000976 transcription cis-regulatory region binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0031965 nuclear membrane", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0008285 negative regulation of cell population proliferation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006915 apoptotic process;GO:0070317 negative regulation of G0 to G1 transition", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZTT0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZTV2-1", "uniprot_id": [ { "id": "D3ZTV2_RAT", "url": "https://www.uniprot.org/uniprot/D3ZTV2", "type": "external" } ], "mass": 118668.0, "length": 1057, "protein_name": "DNA excision repair protein ERCC-5", "gene_name": "Ercc5", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ercc5", "gene_names_refseq": "", "protein_names_uniprotkb": "DNA excision repair protein ERCC-5", "protein_names_refseq": "", "tax_id": 10116, "disease": "disease by infectious agent (Disease Ontology:DOID:0050117); cerebrooculofacioskeletal syndrome 3 (Disease Ontology:DOID:0080913); xeroderma pigmentosum group G (Disease Ontology:DOID:0110849); stomach cancer (Disease Ontology:DOID:10534); lung cancer (Disease Ontology:DOID:1324); melanoma (Disease Ontology:DOID:1909); larynx cancer (Disease Ontology:DOID:2596); Cockayne syndrome (Disease Ontology:DOID:2962); high grade glioma (Disease Ontology:DOID:3070); coronary artery disease (Disease Ontology:DOID:3393); lung non-small cell carcinoma (Disease Ontology:DOID:3908)", "pathway": " (rno:301382)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 11, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008047 enzyme activator activity;GO:0016788 hydrolase activity, acting on ester bonds;GO:0042803 protein homodimerization activity;GO:0046872 metal ion binding;GO:0003684 damaged DNA binding", "go_cellular_component": "GO:0000109 nucleotide-excision repair complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0032991 protein-containing complex;GO:0005662 DNA replication factor A complex", "go_biological_process": "GO:0006281 DNA repair;GO:0043066 negative regulation of apoptotic process;GO:0035264 multicellular organism growth;GO:0009411 response to UV;GO:0000724 double-strand break repair via homologous recombination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZTV2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZTX1-1", "uniprot_id": [ { "id": "D3ZTX1_RAT", "url": "https://www.uniprot.org/uniprot/D3ZTX1", "type": "external" } ], "mass": 82939.0, "length": 772, "protein_name": "Tripartite motif-containing protein 67", "gene_name": "Trim67", "organism": "Rat", "refseq_name": "tripartite motif-containing protein 67 isoform X3", "refseq_ac": [ { "id": "XP_017456793", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017456793", "type": "external" } ], "gene_names_uniprotkb": "Trim67", "gene_names_refseq": "RGD1560667; Trim67", "protein_names_uniprotkb": "Tripartite motif-containing protein 67", "protein_names_refseq": "tripartite motif-containing protein 67 isoform X3", "tax_id": 10116, "disease": "Opitz GBBB syndrome (Disease Ontology:DOID:0080697)", "pathway": " (rno:307938)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "29393594", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton", "go_biological_process": "GO:0046580 negative regulation of Ras protein signal transduction;GO:0010976 positive regulation of neuron projection development;GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZTX1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZTX4-1", "uniprot_id": [ { "id": "D3ZTX4_RAT", "url": "https://www.uniprot.org/uniprot/D3ZTX4", "type": "external" } ], "mass": 515839.0, "length": 4511, "protein_name": "Sucrase-isomaltase, intestinal", "gene_name": "Mgam2; Mgam", "organism": "Rat", "refseq_name": "maltase-glucoamylase", "refseq_ac": [ { "id": "NP_001414380", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414380", "type": "external" } ], "gene_names_uniprotkb": "Mgam2; Mgam; Mgam2", "gene_names_refseq": "Mgam", "protein_names_uniprotkb": "Sucrase-isomaltase, intestinal", "protein_names_refseq": "maltase-glucoamylase, intestinal-like; maltase-glucoamylase", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 8, "predicted_n_glycosites": 0, "predicted_o_glycosites": 8, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 1, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004558 alpha-1,4-glucosidase activity;GO:0016160 amylase activity;GO:0030246 carbohydrate binding;GO:0090599 alpha-glucosidase activity", "go_cellular_component": "GO:0016324 apical plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0000025 maltose catabolic process;GO:1901027 dextrin catabolic process;GO:0005975 carbohydrate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZTX4-1", "record_type": "protein", "filter_code": "0000000.1000000.000100.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZTX5-1", "uniprot_id": [ { "id": "D3ZTX5_RAT", "url": "https://www.uniprot.org/uniprot/D3ZTX5", "type": "external" } ], "mass": 111117.0, "length": 986, "protein_name": "EF hand domain family, member B", "gene_name": "Efhb", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Efhb", "gene_names_refseq": "", "protein_names_uniprotkb": "EF hand domain family, member B", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0061891 calcium ion sensor activity", "go_cellular_component": "GO:0036126 sperm flagellum;GO:0005879 axonemal microtubule;GO:0160111 axonemal A tubule inner sheath", "go_biological_process": "GO:0070884 regulation of calcineurin-NFAT signaling cascade;GO:0030317 flagellated sperm motility;GO:2001256 regulation of store-operated calcium entry", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZTX5-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZU55-1", "uniprot_id": [ { "id": "D3ZU55_RAT", "url": "https://www.uniprot.org/uniprot/D3ZU55", "type": "external" } ], "mass": 75075.0, "length": 719, "protein_name": "Forkhead box protein K1", "gene_name": "Foxk1", "organism": "Rat", "refseq_name": "forkhead box protein K1", "refseq_ac": [ { "id": "NP_001032296", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032296", "type": "external" } ], "gene_names_uniprotkb": "Foxk1", "gene_names_refseq": "Foxk1; RGD1309643", "protein_names_uniprotkb": "Forkhead box protein K1; Myocyte nuclear factor", "protein_names_refseq": "forkhead box protein K1", "tax_id": 10116, "disease": "", "pathway": " (rno:304298); (R-RNO-5689603)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0071889 14-3-3 protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0042594 response to starvation;GO:0010906 regulation of glucose metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZU55-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZUD3-1", "uniprot_id": [ { "id": "D3ZUD3_RAT", "url": "https://www.uniprot.org/uniprot/D3ZUD3", "type": "external" } ], "mass": 46284.0, "length": 440, "protein_name": "WAS/WASL interacting protein family, member 2", "gene_name": "Wipf2", "organism": "Rat", "refseq_name": "WAS/WASL-interacting protein family member 2", "refseq_ac": [ { "id": "NP_001178754", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178754", "type": "external" } ], "gene_names_uniprotkb": "Wipf2", "gene_names_refseq": "RGD1561080; 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Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in metabolic regulation; may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism. Involved in mitotic progression and regulation of the spindle assembly checkpoint by regulating the stability of MAD1L1 mRNA. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may involve histone deacetylases. Involved in the maintenance of embryonic stem (ES) cell identity., [UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0000932 P-body;GO:0030014 CCR4-NOT complex;GO:0030015 CCR4-NOT core complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006417 regulation of translation;GO:0006355 regulation of DNA-templated transcription;GO:0001829 trophectodermal cell differentiation;GO:0007368 determination of left/right symmetry", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZUV9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZV51-1", "uniprot_id": [ { "id": "D3ZV51_RAT", "url": "https://www.uniprot.org/uniprot/D3ZV51", "type": "external" } ], "mass": 35272.0, "length": 316, "protein_name": "Olfactory receptor", "gene_name": "Or5d41b", "organism": "Rat", "refseq_name": "olfactory receptor Olr610", "refseq_ac": [ { "id": "NP_001000336", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000336", "type": "external" } ], "gene_names_uniprotkb": "Or5d41b; LOC100909611; Or5d41", "gene_names_refseq": "Olr610; Or5d41", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 610; olfactory receptor Olr610; olfactory receptor gene Olr610", "tax_id": 10116, "disease": "", "pathway": " (rno:295836)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. 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ENSRNOG00000065077", "gene_names_refseq": "LOC120096991", "protein_names_uniprotkb": "Large ribosomal subunit protein eL31; 60S ribosomal protein L31", "protein_names_refseq": "large ribosomal subunit protein eL31-like", "tax_id": 10116, "disease": "", "pathway": " (rno:120096991)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the large ribosomal subunit. 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"external" } ], "gene_names_uniprotkb": "Dzip3", "gene_names_refseq": "Dzip3; RGD1563278", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase DZIP3; 2.3.2.27; RING-type E3 ubiquitin transferase DZIP3", "protein_names_refseq": "DAZ interacting protein 3, zinc finger; E3 ubiquitin-protein ligase DZIP3", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-983168)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. 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RGD1562200", "gene_names_refseq": "", "protein_names_uniprotkb": "Patatin like phospholipase domain containing 4", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-163560)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004806 triacylglycerol lipase activity;GO:0050253 retinyl-palmitate esterase activity;GO:0004623 phospholipase A2 activity;GO:0016411 acylglycerol O-acyltransferase activity;GO:0051264 mono-olein transacylation activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005811 lipid droplet;GO:0016020 membrane", "go_biological_process": "GO:0016042 lipid catabolic process;GO:0055088 lipid homeostasis;GO:0019433 triglyceride catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A227-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A264-1", "uniprot_id": [ { "id": "D4A264_RAT", "url": "https://www.uniprot.org/uniprot/D4A264", "type": "external" } ], "mass": 40476.0, "length": 377, "protein_name": "15-oxoprostaglandin 13-reductase", "gene_name": "Ptgr3", "organism": "Rat", "refseq_name": "prostaglandin reductase 3", "refseq_ac": [ { "id": "NP_001099599", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099599", "type": "external" } ], "gene_names_uniprotkb": "Ptgr3; Zadh2", "gene_names_refseq": "Ptgr3; Zadh2", "protein_names_uniprotkb": "15-oxoprostaglandin 13-reductase; 1.3.1.48; 15-oxoprostaglandin 13-reductase; Zinc-binding alcohol dehydrogenase domain-containing protein 2", "protein_names_refseq": "prostaglandin reductase 3; zinc binding alcohol dehydrogenase, domain containing 2; zinc-binding alcohol dehydrogenase domain-containing protein 2", "tax_id": 10116, "disease": "", "pathway": " (rno:291403)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest efficiency towards 15-keto-PGE2-alpha. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 1, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.48", "type": "external" }, { "id": "1.3.1.74", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.74", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0047522 15-oxoprostaglandin 13-reductase [NAD(P)+] activity", "go_cellular_component": "GO:0005777 peroxisome", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0045599 negative regulation of fat cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A264-1", "record_type": "protein", "filter_code": "0000000.1000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A281-1", "uniprot_id": [ { "id": "D4A281_RAT", "url": "https://www.uniprot.org/uniprot/D4A281", "type": "external" } ], "mass": 19106.0, "length": 175, "protein_name": "TNF receptor superfamily member 13C", "gene_name": "Tnfrsf13c", "organism": "Rat", "refseq_name": "TNF receptor superfamily member 13C", "refseq_ac": [ { "id": "NP_001418900", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001418900", "type": "external" } ], "gene_names_uniprotkb": "Tnfrsf13c", "gene_names_refseq": "RGD1560810; Tnfrsf13c", "protein_names_uniprotkb": "TNF receptor superfamily member 13C", "protein_names_refseq": "TNF receptor superfamily member 13C; tumor necrosis factor receptor superfamily, member 13c", "tax_id": 10116, "disease": "common variable immunodeficiency 4 (Disease Ontology:DOID:0081147)", "pathway": " (rno:500910); (R-RNO-5668541); (R-RNO-5676594)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "22124120;22391142", "class_list": "", "function": "BAFF/BAFF-R involved in autoantibody production in rats with collagen-induced arthritis via PI3K-Akt-mTOR signaling and the regulation of paeoniflorin., [RefSeq, PubMed]; Soluble BAFF levels inversely correlate with peripheral B cell numbers and the expression of BAFF receptors., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0031295 T cell costimulation;GO:0050776 regulation of immune response;GO:0002636 positive regulation of germinal center formation;GO:0030890 positive regulation of B cell proliferation;GO:0032729 positive regulation of type II interferon production", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D4A281-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A331-1", "uniprot_id": [ { "id": "D4A331_RAT", "url": "https://www.uniprot.org/uniprot/D4A331", "type": "external" } ], "mass": 133091.0, "length": 1198, "protein_name": "Tubulin tyrosine ligase like 4", "gene_name": "Ttll4", "organism": "Rat", "refseq_name": "tubulin monoglutamylase TTLL4", "refseq_ac": [ { "id": "NP_001414011", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414011", "type": "external" } ], "gene_names_uniprotkb": "Ttll4", "gene_names_refseq": "Ttll4", "protein_names_uniprotkb": "Tubulin tyrosine ligase like 4", "protein_names_refseq": "tubulin monoglutamylase TTLL4; tubulin polyglutamylase TTLL4; tubulin tyrosine ligase-like family, member 4", "tax_id": 10116, "disease": "", "pathway": " (rno:690512); (R-RNO-8955332)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "29393594", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0070740 tubulin-glutamic acid ligase activity;GO:0005524 ATP binding;GO:0015631 tubulin binding;GO:0070739 protein-glutamic acid ligase activity", "go_cellular_component": "GO:0005874 microtubule;GO:0036064 ciliary basal body;GO:0097731 9+0 non-motile cilium", "go_biological_process": "GO:0000226 microtubule cytoskeleton organization;GO:0018095 protein polyglutamylation;GO:0018200 peptidyl-glutamic acid modification;GO:0120222 regulation of blastocyst development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A331-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A349-1", "uniprot_id": [ { "id": "D4A349_RAT", "url": "https://www.uniprot.org/uniprot/D4A349", "type": "external" } ], "mass": 81296.0, "length": 739, "protein_name": "Endoplasmic reticulum membrane sensor NFE2L1", "gene_name": "Nfe2l1", "organism": "Rat", "refseq_name": "endoplasmic reticulum membrane sensor NFE2L1 isoform 1", "refseq_ac": [ { "id": "NP_001101763", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101763", "type": "external" } ], "gene_names_uniprotkb": "Nfe2l1", "gene_names_refseq": "Nfe2l1", "protein_names_uniprotkb": "Endoplasmic reticulum membrane sensor NFE2L1; Nuclear factor erythroid 2-related factor 1; Nuclear factor, erythroid derived 2, like 1", "protein_names_refseq": "endoplasmic reticulum membrane sensor NFE2L1 isoform 1; endoplasmic reticulum membrane sensor NFE2L1; nuclear factor erythroid 2-related factor 1; nuclear factor, erythroid 2-like 1; nuclear factor, erythroid derived 2,-like 1", "tax_id": 10116, "disease": "hepatocellular carcinoma (Disease Ontology:DOID:684); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (rno:360610)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "This gene encodes a protein that is involved in globin gene expression in erythrocytes. Confusion has occurred in bibliographic databases for genes in the 'nuclear respiratory factor' and 'nuclear factor (erythroid-derived 2)' families due to a shared symbol or alias pattern of NRF*. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity;GO:0019904 protein domain specific binding;GO:0042802 identical protein binding;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0090575 RNA polymerase II transcription regulator complex;GO:0032991 protein-containing complex", "go_biological_process": "GO:0021781 glial cell fate commitment;GO:0070417 cellular response to cold;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A349-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A3D6-1", "uniprot_id": [ { "id": "D4A3D6_RAT", "url": "https://www.uniprot.org/uniprot/D4A3D6", "type": "external" } ], "mass": 54781.0, "length": 486, "protein_name": "ETS transcription factor ERG", "gene_name": "Erg", "organism": "Rat", "refseq_name": "transcriptional regulator ERG isoform 5", "refseq_ac": [ { "id": "NP_001424636", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001424636", "type": "external" } ], "gene_names_uniprotkb": "Erg", "gene_names_refseq": "Erg", "protein_names_uniprotkb": "ETS transcription factor ERG", "protein_names_refseq": "ERG, ETS transcription factor; avian erythroblastosis virus E-26 (v-ets) oncogene related; transcriptional regulator ERG isoform 5; transcriptional regulator ERG; v-ets avian erythroblastosis virus E26 oncogene; v-ets erythroblastosis virus E26 oncogene homolog; v-ets erythroblastosis virus E26 oncogene like", "tax_id": 10116, "disease": "hereditary lymphedema (Disease Ontology:DOID:0050580); pulmonary venoocclusive disease (Disease Ontology:DOID:5453); osteoarthritis (Disease Ontology:DOID:8398); myeloid leukemia (Disease Ontology:DOID:8692)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:1990837 sequence-specific double-stranded DNA binding;GO:0003700 DNA-binding transcription factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A3D6-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A3G1-1", "uniprot_id": [ { "id": "D4A3G1_RAT", "url": "https://www.uniprot.org/uniprot/D4A3G1", "type": "external" } ], "mass": 35973.0, "length": 317, "protein_name": "Olfactory receptor", "gene_name": "Or52e8b", "organism": "Rat", "refseq_name": "olfactory receptor Olr184", "refseq_ac": [ { "id": "NP_001000182", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000182", "type": "external" } ], "gene_names_uniprotkb": "Or52e8b", "gene_names_refseq": "Olr184; Or52e8b; ratchr1-162890207-162889254_ORF", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 184; olfactory receptor Olr184; olfactory receptor gene Olr184", "tax_id": 10116, "disease": "", "pathway": " (rno:293329)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "29393594", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A3G1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A3G9-1", "uniprot_id": [ { "id": "D4A3G9_RAT", "url": "https://www.uniprot.org/uniprot/D4A3G9", "type": "external" } ], "mass": 59180.0, "length": 550, "protein_name": "Omega-hydroxyceramide transacylase", "gene_name": "Pnpla1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Pnpla1", "gene_names_refseq": "", "protein_names_uniprotkb": "Omega-hydroxyceramide transacylase; 2.3.1.296; Patatin-like phospholipase domain-containing protein 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "Chanarin-Dorfman syndrome (Disease Ontology:DOID:0050729); acquired metabolic disease (Disease Ontology:DOID:0060158); autosomal recessive congenital ichthyosis 10 (Disease Ontology:DOID:0060719); diabetes mellitus (Disease Ontology:DOID:9351); obesity (Disease Ontology:DOID:9970)", "pathway": " (rno:361812)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Omega-hydroxyceramide transacylase involved in the synthesis of omega-O-acylceramides (esterified omega-hydroxyacyl-sphingosine; EOS), which are extremely hydrophobic lipids involved in skin barrier formation. Catalyzes the last step of the synthesis of omega-O-acylceramides by transferring linoleic acid from triglycerides to an omega-hydroxyceramide. Omega-O-acylceramides, are required for the biogenesis of lipid lamellae in the stratum corneum and the formation of the cornified lipid envelope which are essential for the epidermis barrier function. These lipids also play a role in keratinocyte differentiation. May also act on omega-hydroxylated ultra-long chain fatty acids (omega-OH ULCFA) and acylglucosylceramides (GlcEOS)., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.296", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.296", "type": "external" } ], "go_molecular_function": "GO:0004806 triacylglycerol lipase activity;GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups;GO:0030280 structural constituent of skin epidermis;GO:0106341 omega-hydroxyceramide transacylase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005811 lipid droplet;GO:0016020 membrane", "go_biological_process": "GO:0046513 ceramide biosynthetic process;GO:0055088 lipid homeostasis;GO:0061436 establishment of skin barrier;GO:0030216 keratinocyte differentiation;GO:0019433 triglyceride catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A3G9-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A3K2-1", "uniprot_id": [ { "id": "D4A3K2_RAT", "url": "https://www.uniprot.org/uniprot/D4A3K2", "type": "external" } ], "mass": 67740.0, "length": 622, "protein_name": "SHC adaptor protein 4", "gene_name": "Shc4", "organism": "Rat", "refseq_name": "SHC-transforming protein 4", "refseq_ac": [ { "id": "NP_001177994", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001177994", "type": "external" } ], "gene_names_uniprotkb": "Shc4", "gene_names_refseq": "RGD1309182; Shc4", "protein_names_uniprotkb": "SHC adaptor protein 4", "protein_names_refseq": "SHC (Src homology 2 domain containing) family, member 4; SHC-transforming protein 4", "tax_id": 10116, "disease": "", "pathway": " (rno:679845)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "31823725", "class_list": "", "function": "ShcD shows relatively widespread distribution in the adult brain and spinal cord, with prominent levels of staining throughout the olfactory bulb, as well as in sub-structures of the cerebellum and hippocampus, including the subgranular zone. Co-localization studies confirm the expression of ShcD in mature neurons and progenitor cells. ShcD immunoreactivity is primarily localized to axons and somata. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019904 protein domain specific binding;GO:0030971 receptor tyrosine kinase binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0008284 positive regulation of cell population proliferation;GO:0035556 intracellular signal transduction;GO:0048863 stem cell differentiation;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A3K2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A3S1-1", "uniprot_id": [ { "id": "D4A3S1_RAT", "url": "https://www.uniprot.org/uniprot/D4A3S1", "type": "external" } ], "mass": 65325.0, "length": 588, "protein_name": "F-box protein 24", "gene_name": "Fbxo24", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Fbxo24", "gene_names_refseq": "", "protein_names_uniprotkb": "F-box protein 24", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:304374)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:1990756 ubiquitin-like ligase-substrate adaptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0019005 SCF ubiquitin ligase complex", "go_biological_process": "GO:0007283 spermatogenesis;GO:0007338 single fertilization;GO:0006325 chromatin organization;GO:0007005 mitochondrion organization;GO:0030163 protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A3S1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A3S6-1", "uniprot_id": [ { "id": "D4A3S6_RAT", "url": "https://www.uniprot.org/uniprot/D4A3S6", "type": "external" } ], "mass": 80251.0, "length": 750, "protein_name": "MTSS I-BAR domain containing 2", "gene_name": "Mtss2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Mtss2; Mtss1l", "gene_names_refseq": "", "protein_names_uniprotkb": "MTSS I-BAR domain containing 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "intellectual developmental disorder with ocular anomalies and distinctive facial features (Disease Ontology:DOID:0081301)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0003785 actin monomer binding;GO:0005096 GTPase activator activity;GO:0005543 phospholipid binding;GO:0005546 phosphatidylinositol-4,5-bisphosphate binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005925 focal adhesion;GO:0015629 actin cytoskeleton;GO:0030027 lamellipodium;GO:0032587 ruffle membrane", "go_biological_process": "GO:0007009 plasma membrane organization;GO:0061024 membrane organization;GO:0090630 activation of GTPase activity;GO:0036120 cellular response to platelet-derived growth factor stimulus;GO:0097581 lamellipodium organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A3S6-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A447-1", "uniprot_id": [ { "id": "D4A447_RAT", "url": "https://www.uniprot.org/uniprot/D4A447", "type": "external" } ], "mass": 161886.0, "length": 1442, "protein_name": "CD109 antigen", "gene_name": "Cd109", "organism": "Rat", "refseq_name": "CD109 antigen precursor", "refseq_ac": [ { "id": "NP_001102241", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102241", "type": "external" } ], "gene_names_uniprotkb": "Cd109", "gene_names_refseq": "Cd109", "protein_names_uniprotkb": "CD109 antigen", "protein_names_refseq": "CD109 antigen precursor; CD109 antigen", "tax_id": 10116, "disease": "", "pathway": " (rno:363104); (R-RNO-114608); (R-RNO-163125)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Modulates negatively TGFB1 signaling in keratinocytes., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0098552 side of membrane", "go_biological_process": "GO:0001933 negative regulation of protein phosphorylation;GO:0061045 negative regulation of wound healing;GO:0001942 hair follicle development;GO:0010839 negative regulation of keratinocyte proliferation;GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A447-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A460-1", "uniprot_id": [ { "id": "D4A460_RAT", "url": "https://www.uniprot.org/uniprot/D4A460", "type": "external" } ], "mass": 22824.0, "length": 210, "protein_name": "Low density lipoprotein receptor class A domain containing 1", "gene_name": "Ldlrad1", "organism": "Rat", "refseq_name": "low-density lipoprotein receptor class A domain-containing protein 1 isoform X3", "refseq_ac": [ { "id": "XP_006238619", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006238619", "type": "external" } ], "gene_names_uniprotkb": "Ldlrad1", "gene_names_refseq": "Ldlrad1", "protein_names_uniprotkb": "Low density lipoprotein receptor class A domain containing 1", "protein_names_refseq": "low-density lipoprotein receptor class A domain-containing protein 1 isoform X3", "tax_id": 10116, "disease": "", "pathway": " (rno:689088)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0016192 vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A460-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A4R1-1", "uniprot_id": [ { "id": "D4A4R1_RAT", "url": "https://www.uniprot.org/uniprot/D4A4R1", "type": "external" } ], "mass": 95727.0, "length": 897, "protein_name": "Echinoderm microtubule-associated protein-like 3", "gene_name": "B3gat3; Eml3", "organism": "Rat", "refseq_name": "echinoderm microtubule-associated protein-like 3 isoform X1", "refseq_ac": [ { "id": "XP_006231069", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006231069", "type": "external" } ], "gene_names_uniprotkb": "B3gat3; Eml3; B3gat3; Eml3; LOC102551660", "gene_names_refseq": "Eml3; RGD1311368", "protein_names_uniprotkb": "Echinoderm microtubule-associated protein-like 3", "protein_names_refseq": "echinoderm microtubule-associated protein-like 3 isoform X1", "tax_id": 10116, "disease": "Larsen-like syndrome B3GAT3 type (Disease Ontology:DOID:0080575); Duchenne muscular dystrophy (Disease Ontology:DOID:11723)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Regulates mitotic spindle assembly, microtubule (MT)-kinetochore attachment and chromosome separation via recruitment of HAUS augmin-like complex and TUBG1 to the existing MTs and promoting MT-based MT nucleation. Required for proper alignnment of chromosomes during metaphase., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.135", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.135", "type": "external" } ], "go_molecular_function": "GO:0008017 microtubule binding;GO:0015020 glucuronosyltransferase activity;GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity;GO:0072542 protein phosphatase activator activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005819 spindle;GO:0015630 microtubule cytoskeleton;GO:0030496 midbody", "go_biological_process": "GO:0051301 cell division;GO:0000226 microtubule cytoskeleton organization;GO:0007080 mitotic metaphase chromosome alignment;GO:1901673 regulation of mitotic spindle assembly;GO:0090316 positive regulation of intracellular protein transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A4R1-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A521-1", "uniprot_id": [ { "id": "D4A521_RAT", "url": "https://www.uniprot.org/uniprot/D4A521", "type": "external" } ], "mass": 33367.0, "length": 296, "protein_name": "Similar to human chromosome 17 open reading frame 78", "gene_name": "C10h17orf78", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "C10h17orf78; 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Or2aa1; ratchr10-45910921-45909962_ORF", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1463; olfactory receptor Olr1463; olfactory receptor gene Olr1463", "tax_id": 10116, "disease": "", "pathway": " (rno:287363)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "29393594", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A522-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A544-1", "uniprot_id": [ { "id": "D4A544_RAT", "url": "https://www.uniprot.org/uniprot/D4A544", "type": "external" } ], "mass": 68853.0, "length": 602, "protein_name": "DENN domain containing 6A", "gene_name": "Dennd6a", "organism": "Rat", "refseq_name": "protein DENND6A", "refseq_ac": [ { "id": "NP_001127939", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001127939", "type": "external" } ], "gene_names_uniprotkb": "Dennd6a", "gene_names_refseq": "Dennd6a; Fam116a; RGD1306064", "protein_names_uniprotkb": "DENN domain containing 6A", "protein_names_refseq": "DENN/MADD domain containing 6A; family with sequence similarity 116, member A; hypothetical protein MGC38041; protein DENND6A", "tax_id": 10116, "disease": "", "pathway": " (rno:306229); (R-RNO-8876198)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0055037 recycling endosome", "go_biological_process": "GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A544-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A589-1", "uniprot_id": [ { "id": "D4A589_RAT", "url": "https://www.uniprot.org/uniprot/D4A589", "type": "external" } ], "mass": 165751.0, "length": 1472, "protein_name": "Telomerase-binding protein EST1A", "gene_name": "Smg6", "organism": "Rat", "refseq_name": "telomerase-binding protein EST1A", "refseq_ac": [ { "id": "NP_001099278", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099278", "type": "external" } ], "gene_names_uniprotkb": "Smg6", "gene_names_refseq": "LRRGT00040; RGD1309609; Smg6", "protein_names_uniprotkb": "Telomerase-binding protein EST1A; 3.1.-.-", "protein_names_refseq": "Smg-6 homolog, nonsense mediated mRNA decay factor; telomerase-binding protein EST1A", "tax_id": 10116, "disease": "", "pathway": " (rno:287522); (R-RNO-975957)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "22673903;38685156", "class_list": "", "function": "Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini. May have a general role in telomere regulation. Promotes in vitro the ability of TERT to elongate telomeres. Overexpression induces telomere uncapping, chromosomal end-to-end fusions (telomeric DNA persists at the fusion points) and did not perturb TRF2 telomeric localization. Binds to the single-stranded 5'-(GTGTGG)(4)GTGT-3' telomeric DNA, but not to a telomerase RNA template component (TER)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Mechanism of circRNA_SMG6 mediating lung macrophage ECM degradation via miR-570-3p in microplastics-induced emphysema., [RefSeq, PubMed]; Plays a role in nonsense-mediated mRNA decay. Is thought to provide a link to the mRNA degradation machinery as it has endonuclease activity required to initiate NMD, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation. Degrades single-stranded RNA (ssRNA), but not ssDNA or dsRNA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.62", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.62", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0016787 hydrolase activity;GO:0030145 manganese ion binding;GO:0043021 ribonucleoprotein complex binding;GO:0042162 telomeric DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005697 telomerase holoenzyme complex", "go_biological_process": "GO:0032204 regulation of telomere maintenance;GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:1904354 negative regulation of telomere capping", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D4A589-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A598-1", "uniprot_id": [ { "id": "D4A598_RAT", "url": "https://www.uniprot.org/uniprot/D4A598", "type": "external" } ], "mass": 38252.0, "length": 333, "protein_name": "Acyltransferase", "gene_name": "Awat2", "organism": "Rat", "refseq_name": "acyl-CoA wax alcohol acyltransferase 2", "refseq_ac": [ { "id": "NP_001178653", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178653", "type": "external" } ], "gene_names_uniprotkb": "Awat2", "gene_names_refseq": "Awat2; Dgat2l4; RGD1565111", "protein_names_uniprotkb": "Acyltransferase; 2.3.1.-", "protein_names_refseq": "acyl-CoA wax alcohol acyltransferase 2; diacylglycerol O-acyltransferase 2-like 4", "tax_id": 10116, "disease": "dry eye syndrome (Disease Ontology:DOID:10140)", "pathway": " (rno:302425); (R-RNO-1482883); (R-RNO-2187335); (R-RNO-9640463)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, 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"0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A5W8-1", "uniprot_id": [ { "id": "D4A5W8_RAT", "url": "https://www.uniprot.org/uniprot/D4A5W8", "type": "external" } ], "mass": 62470.0, "length": 553, "protein_name": "CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase", "gene_name": "Pgs1", "organism": "Rat", "refseq_name": "CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial", "refseq_ac": [ { "id": "NP_001414415", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414415", "type": "external" } ], "gene_names_uniprotkb": "Pgs1", "gene_names_refseq": "Pgs1; RGD1305052", "protein_names_uniprotkb": "CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; 2.7.8.5", "protein_names_refseq": "CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial", "tax_id": 10116, "disease": "", "pathway": " (rno:303698)", "pathway_count": 1, 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"D4A634_RAT", "url": "https://www.uniprot.org/uniprot/D4A634", "type": "external" } ], "mass": 124637.0, "length": 1105, "protein_name": "Ran-binding protein 6", "gene_name": "Ranbp6", "organism": "Rat", "refseq_name": "ran-binding protein 6", "refseq_ac": [ { "id": "NP_001101054", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101054", "type": "external" } ], "gene_names_uniprotkb": "Ranbp6", "gene_names_refseq": "Ranbp6", "protein_names_uniprotkb": "Ran-binding protein 6", "protein_names_refseq": "ran-binding protein 6", "tax_id": 10116, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (rno:309326)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May function in nuclear protein import as nuclear transport receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, 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localization sequence binding;GO:0061608 nuclear import signal receptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0045202 synapse", "go_biological_process": "GO:0006606 protein import into nucleus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A634-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A680-1", "uniprot_id": [ { "id": "D4A680_RAT", "url": "https://www.uniprot.org/uniprot/D4A680", "type": "external" } ], "mass": 75503.0, "length": 681, "protein_name": "Rubicon like autophagy enhancer", "gene_name": "Rubcnl", "organism": "Rat", "refseq_name": "protein associated with UVRAG as autophagy enhancer isoform X1", "refseq_ac": [ { "id": "XP_008769127", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008769127", "type": "external" } ], "gene_names_uniprotkb": "Rubcnl; RGD1304929", "gene_names_refseq": 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MALT1 promotes necroptosis in stroke rat brain via targeting the A20/RIPK3 pathway., [RefSeq, PubMed]; Protease that enhances BCL10-induced activation: acts via formation of CBM complexes that channel adaptive and innate immune signaling downstream of CARD domain-containing proteins (CARD9, CARD11 and CARD14) to activate NF-kappa-B and MAP kinase p38 pathways which stimulate expression of genes encoding pro-inflammatory cytokines and chemokines. Mediates BCL10 cleavage: MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion. Involved in the induction of T helper 17 cells (Th17) differentiation. Cleaves RC3H1 and ZC3H12A in response to T-cell receptor (TCR) stimulation which releases their cooperatively repressed targets to promote Th17 cell differentiation. Also mediates cleavage of N4BP1 in T-cells following TCR-mediated activation, leading to N4BP1 inactivation. May also have ubiquitin ligase activity: binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Targeting of MALT1 May Improve Functional Recovery and Attenuate Microglia M1 Polarization-Mediated Neuroinflammation During Spinal Cord Injury., [RefSeq, PubMed]; The Weakened Interaction Between HECTD4 and GluN2B in Ischemic Stroke Promotes Calcium Overload and Brain Injury Through a Mechanism Involving the Decrease of GluN2B and MALT1 Ubiquitination., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019209 kinase activator activity;GO:0002020 protease binding;GO:0004175 endopeptidase activity;GO:0042802 identical protein binding;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm;GO:0032449 CBM complex;GO:0002096 polkadots", "go_biological_process": "GO:2000321 positive regulation of T-helper 17 cell differentiation;GO:0045087 innate immune response;GO:0042113 B cell activation;GO:0050852 T cell receptor signaling pathway;GO:0043123 positive regulation of canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "D4A980-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A9G7-1", "uniprot_id": [ { "id": "D4A9G7_RAT", "url": "https://www.uniprot.org/uniprot/D4A9G7", "type": "external" } ], "mass": 34663.0, "length": 312, "protein_name": "Olfactory receptor", "gene_name": "LOC102555599; Or5l14b", "organism": "Rat", "refseq_name": "olfactory receptor Olr602", "refseq_ac": [ { "id": "NP_001000333", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000333", "type": "external" } ], "gene_names_uniprotkb": "LOC102555599; Or5l14b; Or5l14b", "gene_names_refseq": "Olr602; Or5l14b", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 602; olfactory receptor Olr602; olfactory receptor gene Olr602", "tax_id": 10116, "disease": "", "pathway": " (rno:102555599); (rno:295829)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"6.2.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.-", "type": "external" }, { "id": "6.2.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.7", "type": "external" }, { "id": "6.2.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.24", "type": "external" }, { "id": "6.2.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.15", "type": "external" }, { "id": "3.4.24.81", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.81", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.3.1.n7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.n7", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "1.2.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.5", "type": "external" }, { "id": "1.2.1.28", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.28", "type": "external" }, { "id": "1.2.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.7", "type": "external" }, { "id": "1.2.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.48", "type": "external" }, { "id": "1.14.19.17", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.19.17", "type": "external" }, { "id": "5.2.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.-", "type": "external" }, { "id": "3.2.2.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.2.6", "type": "external" }, { "id": "2.3.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.20", "type": "external" }, { "id": "2.3.1.76", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.76", "type": "external" } ], "go_molecular_function": "GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006654 phosphatidic acid biosynthetic process;GO:0008544 epidermis 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"protein_name": "Keratin-associated protein", "gene_name": "Krtap13-1l1", "organism": "Rat", "refseq_name": "keratin-associated protein 13-1-like", "refseq_ac": [ { "id": "XP_002727896", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002727896", "type": "external" } ], "gene_names_uniprotkb": "Krtap13-1l1; LOC100363136", "gene_names_refseq": "Krtap13-1l1", "protein_names_uniprotkb": "Keratin-associated protein", "protein_names_refseq": "keratin-associated protein 13-1-like", "tax_id": 10116, "disease": "", "pathway": " (rno:100363136)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0045095 keratin filament", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4ACE6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ACK9-1", "uniprot_id": [ { "id": "D4ACK9_RAT", "url": "https://www.uniprot.org/uniprot/D4ACK9", "type": "external" } ], "mass": 98009.0, "length": 831, "protein_name": "Zinc finger protein 788", "gene_name": "Zfp788", "organism": "Rat", "refseq_name": "zinc finger protein 788", "refseq_ac": [ { "id": "NP_001403490", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001403490", "type": "external" } ], "gene_names_uniprotkb": "Zfp788; 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(R-RNO-4641263)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0008201 heparin binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0035878 nail development;GO:0016055 Wnt signaling pathway;GO:0090263 positive regulation of canonical Wnt signaling pathway;GO:0030177 positive regulation of Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4ACX0-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LUU6-1", "uniprot_id": [ { "id": "F1LUU6_RAT", "url": "https://www.uniprot.org/uniprot/F1LUU6", "type": "external" } ], "mass": 87842.0, "length": 770, "protein_name": "Rho guanine nucleotide exchange factor 38", "gene_name": "Arhgef38", "organism": "Rat", "refseq_name": "rho guanine nucleotide exchange factor 38", "refseq_ac": [ { "id": "NP_001414563", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414563", "type": "external" } ], "gene_names_uniprotkb": "Arhgef38", "gene_names_refseq": "Arhgef38; RGD1311728", "protein_names_uniprotkb": "Rho guanine nucleotide exchange factor 38", "protein_names_refseq": "Rho guanine nucleotide exchange factor (GEF) 38; rho guanine nucleotide exchange factor 38-like; rho guanine nucleotide exchange factor 38", "tax_id": 10116, "disease": "", "pathway": " (rno:295449); (R-RNO-193648); (R-RNO-416482)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May act as a guanine-nucleotide releasing factor., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LUU6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ADC6-1", "uniprot_id": [ { "id": "D4ADC6_RAT", "url": "https://www.uniprot.org/uniprot/D4ADC6", "type": "external" } ], "mass": 86744.0, "length": 793, "protein_name": "Polyamine-transporter SLC45A4", "gene_name": "Slc45a4", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Slc45a4", "gene_names_refseq": "", "protein_names_uniprotkb": "Polyamine-transporter SLC45A4; Solute carrier family 45 member 4", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Neuronal polyamine-transporter involved in pain perception. Transports polyamines such as putrescine, cadaverine, spermine and spermidine. Expressed in sensory neuron subtypes within the dorsal root ganglion, where it regulates the excitability of C-polymodal nociceptors by mediating polyamine transport., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008506 sucrose:proton symporter activity;GO:0015489 putrescine transmembrane transporter activity;GO:0015203 polyamine transmembrane transporter activity;GO:0015606 spermidine transmembrane transporter activity;GO:0000297 spermine transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0019233 sensory perception of pain;GO:0048266 behavioral response to pain;GO:0015770 sucrose transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4ADC6-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ADQ4-1", "uniprot_id": [ { "id": "D4ADQ4_RAT", "url": "https://www.uniprot.org/uniprot/D4ADQ4", "type": "external" } ], "mass": 41490.0, "length": 368, "protein_name": "Stimulated by retinoic acid 8", "gene_name": "Stra8", "organism": "Rat", "refseq_name": "stimulated by retinoic acid 8", "refseq_ac": [ { "id": "NP_001418743", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001418743", "type": "external" } ], "gene_names_uniprotkb": "Stra8", "gene_names_refseq": "RGD1562852; Stra8", "protein_names_uniprotkb": "Stimulated by retinoic acid 8", "protein_names_refseq": "stimulated by retinoic acid 8; stimulated by retinoic acid gene 8 protein homolog", "tax_id": 10116, "disease": "", "pathway": " (rno:500079)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0048133 male germ-line stem cell asymmetric division;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007283 spermatogenesis;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0071300 cellular response to retinoic acid", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4ADQ4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ADQ8-1", "uniprot_id": [ { "id": "D4ADQ8_RAT", "url": "https://www.uniprot.org/uniprot/D4ADQ8", "type": "external" } ], "mass": 63614.0, "length": 579, "protein_name": "CEA cell adhesion molecule 20", "gene_name": "Ceacam20", "organism": "Rat", "refseq_name": "carcinoembryonic antigen-related cell adhesion molecule 20 precursor", "refseq_ac": [ { "id": "NP_001163795", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163795", "type": "external" } ], "gene_names_uniprotkb": "Ceacam20", "gene_names_refseq": "Ceacam20; 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(R-RNO-418594); (R-RNO-420499)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0050912 detection of chemical stimulus involved in sensory perception of taste", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4AEI0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AEK3-1", "uniprot_id": [ { "id": "D4AEK3_RAT", "url": "https://www.uniprot.org/uniprot/D4AEK3", "type": "external" } ], "mass": 114361.0, "length": 1037, "protein_name": "Cysteine-rich motor neuron 1 protein", "gene_name": "Crim1", "organism": "Rat", "refseq_name": "cysteine-rich motor neuron 1 protein precursor", "refseq_ac": [ { "id": "NP_001162574", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162574", "type": "external" } ], "gene_names_uniprotkb": "Crim1", "gene_names_refseq": "Crim1", "protein_names_uniprotkb": "Cysteine-rich motor neuron 1 protein", "protein_names_refseq": "cysteine rich transmembrane BMP regulator 1 (chordin like); cysteine-rich motor neuron 1 protein precursor; cysteine-rich motor neuron 1", "tax_id": 10116, "disease": "microphthalmia (Disease Ontology:DOID:10629); cataract (Disease Ontology:DOID:83)", "pathway": " (rno:298744)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity;GO:0030165 PDZ domain binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0016020 membrane", "go_biological_process": "GO:0030514 negative regulation of BMP signaling pathway;GO:0045668 negative regulation of osteoblast differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4AEK3-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E9PST6-1", "uniprot_id": [ { "id": "E9PST6_RAT", "url": "https://www.uniprot.org/uniprot/E9PST6", "type": "external" } ], "mass": 28742.0, "length": 250, "protein_name": "Prolactin family 7, subfamily A, member 4", "gene_name": "Prl7a4", "organism": "Rat", "refseq_name": "prolactin family 7, subfamily a, member 4 precursor", "refseq_ac": [ { "id": "NP_001008342", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008342", "type": "external" } ], "gene_names_uniprotkb": "Prl7a4", "gene_names_refseq": "Ghd8; 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protein downstream neighbor of Son isoform 1; protein downstream neighbor of Son", "tax_id": 10116, "disease": "microcephaly, short stature, and limb abnormalities (Disease Ontology:DOID:0081431); microcephaly-micromelia syndrome (Disease Ontology:DOID:0081432); syndrome (Disease Ontology:DOID:225)", "pathway": " (rno:288257)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0030894 replisome;GO:0005634 nucleus;GO:0005657 replication fork", "go_biological_process": "GO:0006260 DNA replication;GO:0000077 DNA damage checkpoint signaling;GO:0007095 mitotic G2 DNA damage checkpoint signaling;GO:0031297 replication fork processing;GO:0033314 mitotic DNA replication checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E9PSU2-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E9PSU5-1", "uniprot_id": [ { "id": "E9PSU5_RAT", "url": "https://www.uniprot.org/uniprot/E9PSU5", "type": "external" } ], "mass": 38334.0, "length": 368, "protein_name": "Heterogeneous nuclear ribonucleoprotein A3", "gene_name": "AABR07048397.1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "AABR07048397.1; 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Binds to the cis-acting response element, A2RE. May be involved in pre-mRNA splicing., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003730 mRNA 3'-UTR binding", "go_cellular_component": "GO:0071013 catalytic step 2 spliceosome", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E9PSU5-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E9PSY2-1", "uniprot_id": [ { "id": "E9PSY2_RAT", "url": "https://www.uniprot.org/uniprot/E9PSY2", "type": "external" } ], "mass": 34286.0, "length": 316, "protein_name": "MAGE family member B4", "gene_name": "Mageb1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Mageb1; 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Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotes dephosphorylation of UPF1. Together with SMG7 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation. Necessary for TERT activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding;GO:0042826 histone deacetylase binding;GO:0042162 telomeric DNA binding;GO:0051721 protein phosphatase 2A binding;GO:0070034 telomerase RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0036464 cytoplasmic ribonucleoprotein granule;GO:0005697 telomerase holoenzyme complex", "go_biological_process": "GO:0032204 regulation of telomere maintenance;GO:0035303 regulation of dephosphorylation;GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "E9PU03-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E9PU26-1", "uniprot_id": [ { "id": "E9PU26_RAT", "url": "https://www.uniprot.org/uniprot/E9PU26", "type": "external" } ], "mass": 31013.0, "length": 267, "protein_name": "Killer cell lectin-like receptor, subfamily A, member 1", "gene_name": "Klra1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Klra1; Klra5; Ly49i3", "gene_names_refseq": "", "protein_names_uniprotkb": "Killer cell lectin-like receptor, subfamily A, member 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "M0R8V3", "ec_number_list": [], "go_molecular_function": "GO:0030246 carbohydrate binding;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0007155 cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E9PU26-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E9PU77-1", "uniprot_id": [ { "id": "E9PU77_RAT", "url": "https://www.uniprot.org/uniprot/E9PU77", "type": "external" } ], "mass": 68780.0, "length": 609, "protein_name": "Synaptotagmin-like protein 3", "gene_name": "Sytl3", "organism": "Rat", "refseq_name": "synaptotagmin-like protein 3 isoform X1", "refseq_ac": [ { "id": "XP_006227950", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006227950", "type": "external" } ], "gene_names_uniprotkb": "Sytl3", "gene_names_refseq": "RGD1561992; Sytl3", "protein_names_uniprotkb": "Synaptotagmin-like protein 3; Exophilin-6", "protein_names_refseq": "synaptotagmin-like protein 3 isoform X1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids in the presence of calcium ions., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, 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"Cell cycle and apoptosis regulator 2", "gene_name": "Ccar2", "organism": "Rat", "refseq_name": "cell cycle and apoptosis regulator protein 2", "refseq_ac": [ { "id": "NP_001163943", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163943", "type": "external" } ], "gene_names_uniprotkb": "Ccar2; RGD1309922", "gene_names_refseq": "Ccar2; RGD1309922", "protein_names_uniprotkb": "Cell cycle and apoptosis regulator 2", "protein_names_refseq": "cell cycle and apoptosis regulator protein 2", "tax_id": 10116, "disease": "", "pathway": " (rno:306007)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, 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"refseq_ac": [], "gene_names_uniprotkb": "Clec4m; Cd209b", "gene_names_refseq": "", "protein_names_uniprotkb": "C-type lectin domain family 4 member M", "protein_names_refseq": "", "tax_id": 10116, "disease": "extrapulmonary tuberculosis (Disease Ontology:DOID:0050598); severe acute respiratory syndrome (Disease Ontology:DOID:2945); pulmonary tuberculosis (Disease Ontology:DOID:2957)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, 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"type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005819 spindle;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0071459 protein localization to chromosome, centromeric region;GO:0051754 meiotic sister chromatid cohesion, centromeric;GO:0007094 mitotic spindle assembly checkpoint signaling;GO:0007091 metaphase/anaphase transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LMI1-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LMQ3-1", "uniprot_id": [ { "id": "F1LMQ3_RAT", "url": "https://www.uniprot.org/uniprot/F1LMQ3", "type": "external" } ], "mass": 39877.0, "length": 353, "protein_name": "26S proteasome non-ATPase regulatory subunit 8", "gene_name": "Psmd8", "organism": "Rat", "refseq_name": "26S proteasome non-ATPase regulatory subunit 8", "refseq_ac": [ { "id": "NP_001094301", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094301", "type": "external" } ], "gene_names_uniprotkb": "Psmd8", "gene_names_refseq": "Psmd8", "protein_names_uniprotkb": "26S proteasome non-ATPase regulatory subunit 8; 26S proteasome regulatory subunit RPN12", "protein_names_refseq": "26S proteasome non-ATPase regulatory subunit 8; proteasome (prosome, macropain) 26S subunit, non-ATPase, 8", "tax_id": 10116, "disease": "", "pathway": " (rno:292766); (R-RNO-1169091); (R-RNO-1234176); (R-RNO-1236978); (R-RNO-174084); (R-RNO-174113); (R-RNO-174154); (R-RNO-174178); (R-RNO-174184); (R-RNO-187577); (R-RNO-195253); (R-RNO-202424); (R-RNO-2467813); (R-RNO-2871837); (R-RNO-349425); (R-RNO-350562); (R-RNO-382556); (R-RNO-450408); (R-RNO-4608870); (R-RNO-4641257); (R-RNO-4641258); (R-RNO-5358346); (R-RNO-5607761); (R-RNO-5607764); (R-RNO-5610780); (R-RNO-5610785); (R-RNO-5632684); (R-RNO-5658442); (R-RNO-5668541); (R-RNO-5676590); (R-RNO-5687128); (R-RNO-5689603); (R-RNO-5689880); (R-RNO-68867); (R-RNO-68949); (R-RNO-69017); (R-RNO-69481); (R-RNO-69601); (R-RNO-75815); (R-RNO-8852276); (R-RNO-8854050); (R-RNO-8939236); (R-RNO-8941858); (R-RNO-8948751); (R-RNO-8951664); (R-RNO-9020702); (R-RNO-9755511); (R-RNO-9762114); (R-RNO-9766229); (R-RNO-983168); (R-RNO-9907900); (R-RNO-9929356); (R-RNO-9929491); (R-RNO-9931269); (R-RNO-9932298); (R-RNO-9954709)", "pathway_count": 56, "publication_count": 1, "publication_id_list": "29398115", "class_list": "", "function": "Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, 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"uniprot_canonical_ac": "F1LNJ1-1", "uniprot_id": [ { "id": "F1LNJ1_RAT", "url": "https://www.uniprot.org/uniprot/F1LNJ1", "type": "external" } ], "mass": 284858.0, "length": 2526, "protein_name": "Leucine-rich repeat serine/threonine-protein kinase 2", "gene_name": "Lrrk2", "organism": "Rat", "refseq_name": "leucine-rich repeat serine/threonine-protein kinase 2 isoform X1", "refseq_ac": [ { "id": "XP_063119437", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063119437", "type": "external" } ], "gene_names_uniprotkb": "Lrrk2", "gene_names_refseq": "Lrrk2", "protein_names_uniprotkb": "Leucine-rich repeat serine/threonine-protein kinase 2; 2.7.11.1", "protein_names_refseq": "leucine-rich repeat serine/threonine-protein kinase 2 isoform X1", "tax_id": 10116, "disease": "synucleinopathy (Disease Ontology:DOID:0050890); Parkinson's disease 8 (Disease Ontology:DOID:0060371); Parkinsonism (Disease Ontology:DOID:0080855); neurodegenerative disease (Disease Ontology:DOID:1289); Parkinson's disease (Disease Ontology:DOID:14330); cancer (Disease Ontology:DOID:162); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); rheumatoid arthritis (Disease Ontology:DOID:7148); Crohn's disease (Disease Ontology:DOID:8778); frontotemporal dementia (Disease Ontology:DOID:9255); diabetic neuropathy (Disease Ontology:DOID:9743)", "pathway": " (rno:300160); (R-RNO-8857538)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, 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"type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "3.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.1", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.34", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "2.7.11.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.19", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.11.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.4", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.4.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.18", "type": "external" }, { "id": "3.1.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.24.-", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0003779 actin binding;GO:0003924 GTPase activity;GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:1902902 negative regulation of autophagosome assembly;GO:0031344 regulation of cell projection organization;GO:0051900 regulation of mitochondrial depolarization;GO:1900244 positive regulation of synaptic vesicle endocytosis;GO:0060628 regulation of ER to Golgi vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1LNJ1-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LP29-1", "uniprot_id": [ { "id": "F1LP29_RAT", "url": "https://www.uniprot.org/uniprot/F1LP29", "type": "external" } ], "mass": 86688.0, "length": 789, "protein_name": "Centrosomal protein of 78 kDa", "gene_name": "Cep78", "organism": "Rat", "refseq_name": "centrosomal protein of 78 kDa isoform 1", "refseq_ac": [ { "id": "NP_068509", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_068509", "type": "external" } ], "gene_names_uniprotkb": "Cep78", "gene_names_refseq": "Cep78; Ip63", "protein_names_uniprotkb": "Centrosomal protein of 78 kDa", "protein_names_refseq": "centrosomal protein 78kDa; centrosomal protein of 78 kDa isoform 1; centrosomal protein of 78 kDa", "tax_id": 10116, "disease": "", "pathway": " (rno:60347); (R-RNO-2565942); (R-RNO-380259); (R-RNO-380270); (R-RNO-380284); (R-RNO-380320); (R-RNO-5620912); (R-RNO-8854518)", "pathway_count": 8, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Centriole wall protein that localizes to mature centrioles and regulates centriole and cilia biogenesis. Involved in centrosome duplication: required for efficient PLK4 centrosomal localization and PLK4-induced overduplication of centrioles. Involved in cilium biogenesis and controls cilium length. Acts as a regulator of protein stability by preventing ubiquitination of centrosomal proteins, such as CCP110 and tektins. Associates with the EDVP complex, preventing ubiquitination and degradation of CCP110. Promotes deubiquitination of tektin proteins (TEKT1, TEKT2, TEK3, TEKT4 and TEKT5) via its interaction with USP16., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, 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"length": 494, "protein_name": "Forkhead box D2", "gene_name": "Foxd2", "organism": "Rat", "refseq_name": "forkhead box protein D2", "refseq_ac": [ { "id": "NP_001386132", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386132", "type": "external" } ], "gene_names_uniprotkb": "Foxd2", "gene_names_refseq": "Foxd2", "protein_names_uniprotkb": "Forkhead box D2", "protein_names_refseq": "forkhead box protein D2", "tax_id": 10116, "disease": "", "pathway": " (rno:313504)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, 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{ "id": "SCN7A_RAT", "url": "https://www.uniprot.org/uniprot/F1LQQ7", "type": "external" } ], "mass": 192136.0, "length": 1680, "protein_name": "Sodium channel protein type 7 subunit alpha", "gene_name": "Scn7a", "organism": "Rat", "refseq_name": "sodium channel protein type 7 subunit alpha", "refseq_ac": [ { "id": "NP_001375437", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001375437", "type": "external" } ], "gene_names_uniprotkb": "Scn7a; Scl11", "gene_names_refseq": "Na-G; SCL-11; Scn6a; Scn7a", "protein_names_uniprotkb": "Sodium channel protein type 7 subunit alpha; Glial sodium channel alpha subunit; Na-G; Nax channel; SCL-11; Voltage-gated sodium channel-like protein", "protein_names_refseq": "glial sodium channel alpha subunit; nax channel; sodium channel protein type 7 subunit alpha; sodium channel voltage-gated type VI alpha polypeptide; sodium channel, voltage-gated, type 6, alpha polypeptide; sodium channel, voltage-gated, type VII, alpha subunit; voltage-gated sodium channel-like protein", "tax_id": 10116, "disease": "generalized epilepsy with febrile seizures plus (Disease Ontology:DOID:0060170); Dravet syndrome (Disease Ontology:DOID:0080422); generalized epilepsy with febrile seizures plus 2 (Disease Ontology:DOID:0111294); epilepsy (Disease Ontology:DOID:1826); anxiety disorder (Disease Ontology:DOID:2030); brain infarction (Disease Ontology:DOID:3454)", "pathway": " (rno:64155)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "1379737;15102913;19765660;21084682;22673903;23026072;32027092;37783507;9001394", "class_list": "", "function": "Data demonstrate predominant localisation of Na(V)1.6 and Na(V)1.7 on SGN cell bodies and Na(V)1.1 on axonal processes in rat brain., [RefSeq, PubMed]; NaX Channel Is a Physiological [Na[+]] Detector in Oxytocin- and Vasopressin-Releasing Magnocellular Neurosecretory Cells of the Rat Supraoptic Nucleus. Publication Status: Online-Only, [RefSeq, PubMed]; Sodium leak channel functioning as an osmosensor regulating sodium ion levels in various tissues and organs. While most sodium channels are voltage-gated, SCN7A is not and lets sodium flow through membrane along its concentration gradient (PubMed:21084682, PubMed:9001394). In glial cells of the central nervous system, senses body-fluid sodium levels and controls salt intake behavior as well as voluntary water intake through activation of nearby neurons to maintain appropriate sodium levels in the body (By similarity). By mediating sodium influx into keratinocytes, also plays a role in skin barrier homeostasis (By similarity)., [UniProtKB, UniProtKB, UniProtKB, PubMed, PubMed]; The results of this study demonstrated that enhanced expression of SCN7A/Nax channel within distinct subpopulation of DRG neurons contributes to bone cancer pain by increasing the excitability of these neurons, [RefSeq, PubMed]; The sodium channel NaX : Possible player in excitation-contraction coupling., [RefSeq, PubMed]; This study shows that a neuronal population of the median preoptic nucleus acts as functional Na+ sensors and that the Na(X) channel might represent the molecular basis for the extracellular sodium level sensing in these neurons., [RefSeq, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 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0.1, "record_id": "F1LQU1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LRA5-1", "uniprot_id": [ { "id": "F1LRA5_RAT", "url": "https://www.uniprot.org/uniprot/F1LRA5", "type": "external" } ], "mass": 138036.0, "length": 1275, "protein_name": "Proteoglycan 4", "gene_name": "Prg4", "organism": "Rat", "refseq_name": "proteoglycan 4 precursor", "refseq_ac": [ { "id": "NP_001099432", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099432", "type": "external" } ], "gene_names_uniprotkb": "Prg4", "gene_names_refseq": "Prg4", "protein_names_uniprotkb": "Proteoglycan 4", "protein_names_refseq": "lubricin; proteoglycan 4 precursor; proteoglycan 4, (megakaryocyte stimulating factor, articular superficial zone protein, camptodactyly, arthropathy, coxa vara, pericarditis syndrome)", "tax_id": 10116, "disease": "camptodactyly-arthropathy-coxa vara-pericarditis syndrome (Disease Ontology:DOID:0090127); pericarditis (Disease Ontology:DOID:1787)", "pathway": "", "pathway_count": 0, "publication_count": 6, "publication_id_list": "19790069;21041994;32716572;34459483;35917632;38897120", "class_list": "", "function": "Blocking TNFalpha resulted in a chondroprotective effect, exemplified by increased lubricin deposition on articular cartilage and a decrease in sGAG release from articular cartilage in an animal model of posttraumatic arthritis., [RefSeq, PubMed]; Effects of in vivo cyclic compressive loading on the distribution of local Col2 and superficial lubricin in rat knee cartilage., [RefSeq, PubMed]; Immunohistochemical evaluation of autotaxin and lubricin in mild osteoarthritic rat model performing moderate physical activity., [RefSeq, PubMed]; PRG4 is synthesized and secreted by condylar cartilage chondrocytes and its expression is differentially regulated by IL-1alpha and TGF-beta1., [RefSeq, PubMed]; PRG4 mitigates hemorrhagic shock-induced cardiac injury by inhibiting mitochondrial dysregulation, oxidative stress and NLRP3-mediated pyroptosis., [RefSeq, PubMed]; Proteoglycan 4 (lubricin) is a highly sialylated glycoprotein associated with cardiac valve damage in animal models of infective endocarditis., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 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"0000000.0000110.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LRM4-1", "uniprot_id": [ { "id": "F1LRM4_RAT", "url": "https://www.uniprot.org/uniprot/F1LRM4", "type": "external" } ], "mass": 40687.0, "length": 377, "protein_name": "Homeobox protein DBX2", "gene_name": "Dbx2", "organism": "Rat", "refseq_name": "homeobox protein DBX2 isoform 1", "refseq_ac": [ { "id": "NP_001418946", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001418946", "type": "external" } ], "gene_names_uniprotkb": "Dbx2", "gene_names_refseq": "Dbx2", "protein_names_uniprotkb": "Homeobox protein DBX2; Developing brain homeobox protein 2", "protein_names_refseq": "homeobox protein DBX2 isoform 1; homeobox protein DBX2", "tax_id": 10116, "disease": "", "pathway": " (rno:541457)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, 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[ { "id": "F1LVL5_RAT", "url": "https://www.uniprot.org/uniprot/F1LVL5", "type": "external" } ], "mass": 164632.0, "length": 1487, "protein_name": "Shroom family member 4", "gene_name": "Shroom4", "organism": "Rat", "refseq_name": "protein Shroom4", "refseq_ac": [ { "id": "NP_001178659", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178659", "type": "external" } ], "gene_names_uniprotkb": "Shroom4", "gene_names_refseq": "RGD1563434; Shroom4", "protein_names_uniprotkb": "Shroom family member 4", "protein_names_refseq": "protein Shroom4", "tax_id": 10116, "disease": "", "pathway": " (rno:317391)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "22673903;28262662;38843836", "class_list": "", "function": "Shrm4 interaction with GABA-B receptors shapes inhibitory neurotransmission. 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97273.0, "length": 861, "protein_name": "E3 ubiquitin-protein ligase HECTD3", "gene_name": "Hectd3", "organism": "Rat", "refseq_name": "E3 ubiquitin-protein ligase HECTD3", "refseq_ac": [ { "id": "NP_001386141", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386141", "type": "external" } ], "gene_names_uniprotkb": "Hectd3; RGD1309823", "gene_names_refseq": "Hectd3; RGD1309823", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase HECTD3; 2.3.2.26; HECT domain-containing protein 3; HECT-type E3 ubiquitin transferase HECTD3", "protein_names_refseq": "E3 ubiquitin-protein ligase HECTD3; HECT domain containing E3 ubiquitin protein ligase 3", "tax_id": 10116, "disease": "", "pathway": " (rno:313525); (R-RNO-983168)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "35913790", "class_list": "", "function": "HECTD3 promotes NLRP3 inflammasome and pyroptosis to exacerbate diabetes-related cognitive impairment by stabilising MALT1 to regulate JNK pathway., [RefSeq, 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"biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0014069 postsynaptic density;GO:0030426 growth cone", "go_biological_process": "GO:0051963 regulation of synapse assembly;GO:0007413 axonal fasciculation;GO:0021772 olfactory bulb development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LQP7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MJN4-1", "uniprot_id": [ { "id": "SEPT4_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MJN4", "type": "external" } ], "mass": 53083.0, "length": 459, "protein_name": "Septin-4", "gene_name": "Septin4", "organism": "Rat", "refseq_name": "septin-4 isoform 5", "refseq_ac": [ { "id": "NP_001401264", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001401264", "type": "external" } ], "gene_names_uniprotkb": "Septin4; Arts; Bh5; Gm11492; Pnut12; Sep4; Sept4", "gene_names_refseq": "EG3-1RVC; EG3RVC; Pnutl2; Sept4; Septin4; hCDCREL-2", "protein_names_uniprotkb": "Septin-4; Apoptosis-related protein in the TGF-beta signaling pathway; Arts; Bradeion beta; Brain protein H5; CE5B3 beta; Cell division control-related protein 2; Peanut-like protein 2; hCDCREL-2", "protein_names_refseq": "CE5B3 beta; apoptosis-related protein in the TGF-beta signaling pathway; arts; bradeion beta; brain protein H5; cell division control-related protein 2; expression gene 3 in rat visual cortex; expression gene 3-1 in rat visual cortex; peanut-like 2; peanut-like protein 2; septin-4 isoform 5", "tax_id": 10116, "disease": "Lewy body dementia (Disease Ontology:DOID:12217); neurodegenerative disease (Disease Ontology:DOID:1289); Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (R-RNO-111457); (R-RNO-111469)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "18938227;22673903", "class_list": "", "function": "Filament-forming cytoskeletal GTPase., [UniProtKB, UniProtKB]; Filament-forming cytoskeletal GTPase. Pro-apoptotic protein involved in LGR5-positive intestinal stem cell and Paneth cell expansion in the intestines, via its interaction with XIAP (By similarity). May also play a role in the regulation of cell fate in the intestine (By similarity). Positive regulator of apoptosis involved in hematopoietic stem cell homeostasis; via its interaction with XIAP (By similarity). Negative regulator of repair and hair follicle regeneration in response to injury, due to inhibition of hair follicle stem cell proliferation, potentially via its interaction with XIAP (By similarity). Plays an important role in male fertility and sperm motility (By similarity). During spermiogenesis, essential for the establishment of the annulus (a fibrous ring structure connecting the midpiece and the principal piece of the sperm flagellum) which is a requisite for the structural and mechanical integrity of the sperm (By similarity). Involved in the migration of cortical neurons and the formation of neuron leading processes during embryonic development (By similarity). Required for dopaminergic metabolism in presynaptic autoreceptors; potentially via activity as a presynaptic scaffold protein (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0000287 magnesium ion binding;GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0097227 sperm annulus;GO:0005940 septin ring;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0030424 axon", "go_biological_process": "GO:0030382 sperm mitochondrion organization;GO:0048729 tissue morphogenesis;GO:2000647 negative regulation of stem cell proliferation;GO:0043065 positive regulation of apoptotic process;GO:0001764 neuron migration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A096MJN4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0RA86-1", "uniprot_id": [ { "id": "M0RA86_RAT", "url": "https://www.uniprot.org/uniprot/M0RA86", "type": "external" } ], "mass": 66000.0, "length": 595, "protein_name": "Coiled-coil domain containing 9", "gene_name": "Ccdc9", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ccdc9; Inafm1; LOC684934", "gene_names_refseq": "", "protein_names_uniprotkb": "Coiled-coil domain containing 9", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0035145 exon-exon junction complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0RA86-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Z4YNJ9-1", "uniprot_id": [ { "id": "Z4YNJ9_RAT", "url": "https://www.uniprot.org/uniprot/Z4YNJ9", "type": "external" } ], "mass": 41632.0, "length": 359, "protein_name": "Stearoyl-coenzyme A desaturase 3", "gene_name": "Scd3", "organism": "Rat", "refseq_name": "stearoyl-coenzyme A desaturase 3", "refseq_ac": [ { "id": "NP_001419478", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001419478", "type": "external" } ], "gene_names_uniprotkb": "Scd3; LOC681458", "gene_names_refseq": "Scd3", "protein_names_uniprotkb": "Stearoyl-coenzyme A desaturase 3", "protein_names_refseq": "acyl-CoA desaturase 3; stearoyl-coenzyme A desaturase 3", "tax_id": 10116, "disease": "restrictive cardiomyopathy (Disease Ontology:DOID:397)", "pathway": " (rno:681458)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0016215 acyl-CoA desaturase activity;GO:0005506 iron ion binding;GO:0004768 stearoyl-CoA 9-desaturase activity;GO:0032896 palmitoyl-CoA 9-desaturase activity", "go_cellular_component": "GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006633 fatty acid biosynthetic process;GO:0006636 unsaturated fatty acid biosynthetic process;GO:1903966 monounsaturated fatty acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Z4YNJ9-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A567-1", "uniprot_id": [ { "id": "D4A567_RAT", "url": "https://www.uniprot.org/uniprot/D4A567", "type": "external" } ], "mass": 67155.0, "length": 621, "protein_name": "BUB3 mitotic checkpoint protein", "gene_name": "Bub3", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Bub3", "gene_names_refseq": "", "protein_names_uniprotkb": "BUB3 mitotic checkpoint protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (rno:361662)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "38843836", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0000776 kinetochore;GO:0033597 mitotic checkpoint complex", "go_biological_process": "GO:0008608 attachment of spindle microtubules to kinetochore;GO:0034501 protein localization to kinetochore;GO:0051983 regulation of chromosome segregation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "D4A567-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R7B3-1", "uniprot_id": [ { "id": "M0R7B3_RAT", "url": "https://www.uniprot.org/uniprot/M0R7B3", "type": "external" } ], "mass": 31159.0, "length": 269, "protein_name": "MORN repeat-containing protein 3", "gene_name": "Morn3", "organism": "Rat", "refseq_name": "MORN repeat containing 3 isoform 1", "refseq_ac": [ { "id": "NP_001418817", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001418817", "type": "external" } ], "gene_names_uniprotkb": "Morn3; LOC687615", "gene_names_refseq": "Morn3", "protein_names_uniprotkb": "MORN repeat-containing protein 3", "protein_names_refseq": "MORN repeat containing 3 isoform 1; MORN repeat-containing protein 3", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Assembles a suppression complex (suppresome) by tethering SIRT1 and MDM2 to regulate composite modifications of p53/TP53. Confers both deacetylation-mediated functional inactivation, by SIRT1, and ubiquitination-dependent degradation, by MDM2, of p53/TP53, promoting a proliferative and cell survival behaviors. May play a role in the regulation of spermatogenesis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0001669 acrosomal vesicle", "go_biological_process": "GO:1901797 negative regulation of signal transduction by p53 class mediator", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R7B3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R9E4-1", "uniprot_id": [ { "id": "M0R9E4_RAT", "url": "https://www.uniprot.org/uniprot/M0R9E4", "type": "external" } ], "mass": 119510.0, "length": 1045, "protein_name": "Coiled-coil domain containing 57", "gene_name": "Ccdc57", "organism": "Rat", "refseq_name": "coiled-coil domain-containing protein 57 isoform X8", "refseq_ac": [ { "id": "XP_038943494", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038943494", "type": "external" } ], "gene_names_uniprotkb": "Ccdc57", "gene_names_refseq": "Ccdc57", "protein_names_uniprotkb": "Coiled-coil domain containing 57", "protein_names_refseq": "coiled-coil domain-containing protein 57 isoform X8", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005813 centrosome;GO:0005814 centriole;GO:0034451 centriolar satellite;GO:0036064 ciliary basal body", "go_biological_process": "GO:0003351 epithelial cilium movement involved in extracellular fluid movement;GO:0045931 positive regulation of mitotic cell cycle;GO:0000086 G2/M transition of mitotic cell cycle;GO:0060271 cilium assembly;GO:0007020 microtubule nucleation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R9E4-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F7FFR1-1", "uniprot_id": [ { "id": "F7FFR1_RAT", "url": "https://www.uniprot.org/uniprot/F7FFR1", "type": "external" } ], "mass": 65229.0, "length": 578, "protein_name": "Probable arginine--tRNA ligase, mitochondrial", "gene_name": "Rars2", "organism": "Rat", "refseq_name": "probable arginine--tRNA ligase, mitochondrial isoform X1", "refseq_ac": [ { "id": "XP_006238048", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006238048", "type": "external" } ], "gene_names_uniprotkb": "Rars2", "gene_names_refseq": "Rars2; 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2.7.7.9", "protein_names_refseq": "", "tax_id": 10116, "disease": "developmental and epileptic encephalopathy 83 (Disease Ontology:DOID:0112218); cancer (Disease Ontology:DOID:162)", "pathway": " (rno:289827); (R-RNO-173599); (R-RNO-3322077)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.9", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.9", "type": "external" } ], "go_molecular_function": "GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity;GO:0042802 identical protein binding;GO:0032557 pyrimidine ribonucleotide binding;GO:0005536 D-glucose binding;GO:0051748 UTP-monosaccharide-1-phosphate uridylyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0005978 glycogen biosynthetic process;GO:0006011 UDP-alpha-D-glucose metabolic process;GO:0007420 brain development;GO:0005977 glycogen metabolic process;GO:0019255 glucose 1-phosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K542-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZUX2-1", "uniprot_id": [ { "id": "D3ZUX2_RAT", "url": "https://www.uniprot.org/uniprot/D3ZUX2", "type": "external" } ], "mass": 38520.0, "length": 346, "protein_name": "Glycosyltransferase 1 domain-containing protein 1", "gene_name": "Glt1d1", "organism": "Rat", "refseq_name": "glycosyltransferase 1 domain-containing protein 1 isoform 1", "refseq_ac": [ { "id": "NP_001418661", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001418661", "type": "external" } ], "gene_names_uniprotkb": "Glt1d1", "gene_names_refseq": "Glt1d1; 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Jun activation domain-binding protein 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (R-RNO-5696394); (R-RNO-6781823); (R-RNO-8856825); (R-RNO-8951664); (R-RNO-9929356)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008237 metallopeptidase activity;GO:0046872 metal ion binding;GO:0019784 deNEDDylase activity;GO:0035718 macrophage migration inhibitory factor binding;GO:0019899 enzyme binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0008180 COP9 signalosome;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0006508 proteolysis;GO:1903894 regulation of IRE1-mediated unfolded protein response;GO:1990182 exosomal secretion;GO:0043065 positive regulation of apoptotic process;GO:0043066 negative regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F7EUU4-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R3X3-1", "uniprot_id": [ { "id": "M0R3X3_RAT", "url": "https://www.uniprot.org/uniprot/M0R3X3", "type": "external" } ], "mass": 150833.0, "length": 1373, "protein_name": "Rho guanine nucleotide exchange factor 10", "gene_name": "Arhgef10", "organism": "Rat", "refseq_name": "rho guanine nucleotide exchange factor 10", "refseq_ac": [ { "id": "NP_001413962", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001413962", "type": "external" } ], "gene_names_uniprotkb": "Arhgef10; RGD1565043", "gene_names_refseq": "Arhgef10; RGD1565043", "protein_names_uniprotkb": "Rho guanine nucleotide exchange factor 10", "protein_names_refseq": "Rho guanine nucleotide exchange factor (GEF) 10; rho guanine nucleotide exchange factor 10", "tax_id": 10116, "disease": "alcohol-related birth defects (Disease Ontology:DOID:0050668); autism spectrum disorder (Disease Ontology:DOID:0060041)", "pathway": " (rno:306618); (R-RNO-193648); (R-RNO-416482); (R-RNO-8980692); (R-RNO-9013026); (R-RNO-9013106); (R-RNO-9013148); (R-RNO-9013149)", "pathway_count": 8, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May play a role in developmental myelination of peripheral nerves., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity;GO:0019894 kinesin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005813 centrosome", "go_biological_process": "GO:0051056 regulation of small GTPase mediated signal transduction;GO:0051496 positive regulation of stress fiber assembly;GO:0090307 mitotic spindle assembly;GO:0030036 actin cytoskeleton organization;GO:0035025 positive regulation of Rho protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R3X3-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JW93-1", "uniprot_id": [ { "id": "A0A0G2JW93_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JW93", "type": "external" } ], "mass": 20379.0, "length": 168, "protein_name": "High mobility group protein B4", "gene_name": "Hmgb4l2; Hmgb4l4; Hmgb4l6; Hmgb4l7; LOC103694587; LOC120099255", "organism": "Rat", "refseq_name": "high mobility group protein B4-like", "refseq_ac": [ { "id": "XP_003752207", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003752207", "type": "external" } ], "gene_names_uniprotkb": "Hmgb4l2; Hmgb4l4; Hmgb4l6; Hmgb4l7; LOC103694587; LOC120099255; Hmgb4l1; Hmgb4l2; Hmgb4l4; Hmgb4l6; Hmgb4l7; Hmgb4l8; Hmgb4l9; LOC100364877; LOC103690902; LOC103690904; LOC108349258; LOC108352140; LOC120099255; LOC120099272; LOC120099313; LOC134484169; LOC681067; LOC688702; RGD1560585", "gene_names_refseq": "Hmgb4l1", "protein_names_uniprotkb": "High mobility group protein B4", "protein_names_refseq": "high mobility group protein B4-like", "tax_id": 10116, "disease": "", "pathway": " (rno:100364877); (rno:103694587); (rno:120099255); (rno:120099313); (rno:317584); (rno:317597); (rno:317604); (rno:681067); (rno:688702)", "pathway_count": 9, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:0006338 chromatin remodeling", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JW93-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M2D4-1", "uniprot_id": [ { "id": "F1M2D4_RAT", "url": "https://www.uniprot.org/uniprot/F1M2D4", "type": "external" } ], "mass": 163594.0, "length": 1505, "protein_name": "Rho GTPase activating protein 23", "gene_name": "Arhgap23", "organism": "Rat", "refseq_name": "rho GTPase-activating protein 23", "refseq_ac": [ { "id": "NP_001415678", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001415678", "type": "external" } ], "gene_names_uniprotkb": "Arhgap23", "gene_names_refseq": "Arhgap23l; Arhgap23", "protein_names_uniprotkb": "Rho GTPase activating protein 23", "protein_names_refseq": "Rho GTPase activating protein 23 like; pulmonary surfactant-associated protein D-like; rho GTPase-activating protein 23; translation initiation factor IF-2-like", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-8980692); (R-RNO-9013149)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "22673903;38843836", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "F1M2D4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M4Q3-1", "uniprot_id": [ { "id": "F1M4Q3_RAT", "url": "https://www.uniprot.org/uniprot/F1M4Q3", "type": "external" } ], "mass": 611572.0, "length": 5635, "protein_name": "Hemicentin-1", "gene_name": "Hmcn1", "organism": "Rat", "refseq_name": "hemicentin-1 precursor", "refseq_ac": [ { "id": "NP_001258221", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258221", "type": "external" } ], "gene_names_uniprotkb": "Hmcn1", "gene_names_refseq": "Hmcn1; RGD1564772", "protein_names_uniprotkb": "Hemicentin-1; Fibulin-6", "protein_names_refseq": "hemicentin-1 precursor", "tax_id": 10116, "disease": "age related macular degeneration 1 (Disease Ontology:DOID:0110014)", "pathway": " (rno:289094)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "16641100;29488390", "class_list": "", "function": "Identify HMCN1 as a new molecule involved in the dynamic changes of podocyte foot processes in glomerular disease., [RefSeq, PubMed]; Involved in transforming growth factor beta-mediated rearrangement of the podocyte cytoskeleton which includes reduction of F-actin fibers and broadening, flattening and elongation of podocytes. Plays a role in basement membrane organization. May promote cleavage furrow maturation during cytokinesis in preimplantation embryos. May play a role in the architecture of adhesive and flexible epithelial cell junctions. May play a role during myocardial remodeling by imparting an effect on cardiac fibroblast migration., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0008046 axon guidance receptor activity", "go_cellular_component": "GO:0031012 extracellular matrix;GO:0005576 extracellular region;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005938 cell cortex", "go_biological_process": "GO:0050808 synapse organization;GO:0009617 response to bacterium;GO:0030036 actin cytoskeleton organization;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0071711 basement membrane organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1M4Q3-1", "record_type": "protein", "filter_code": "0000000.0000111.000100.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K402-1", "uniprot_id": [ { "id": "A0A0G2K402_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K402", "type": "external" } ], "mass": 63350.0, "length": 591, "protein_name": "Myelin expression factor 2", "gene_name": "Myef2; Slc24a5", "organism": "Rat", "refseq_name": "myelin expression factor 2", "refseq_ac": [ { "id": "NP_001013223", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013223", "type": "external" } ], "gene_names_uniprotkb": "Myef2; Slc24a5", "gene_names_refseq": "Myef2", "protein_names_uniprotkb": "Myelin expression factor 2", "protein_names_refseq": "myelin basic protein expression factor 2, repressor; myelin expression factor 2", "tax_id": 10116, "disease": "ocular albinism 1 (Disease Ontology:DOID:0050633); oculocutaneous albinism type VI (Disease Ontology:DOID:0080614)", "pathway": " (rno:311387); (rno:679712); (R-RNO-425561)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) to the melanosome in exchange for 4 cytoplasmic Na(+). Involved in pigmentation, possibly by participating in ion transport in melanosomes. Predominant sodium-calcium exchanger in melanocytes., [UniProtKB, UniProtKB]; Transcriptional repressor of the myelin basic protein gene (MBP). Binds to the proximal MB1 element 5'-TTGTCC-3' of the MBP promoter. Its binding to MB1 and function are inhibited by PURA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005262 calcium channel activity;GO:0015293 symporter activity;GO:0008273 calcium, potassium:sodium antiporter activity;GO:0015085 calcium ion transmembrane transporter activity;GO:0003729 mRNA binding", "go_cellular_component": "GO:0016020 membrane;GO:0042470 melanosome;GO:0005802 trans-Golgi network;GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0048022 negative regulation of melanin biosynthetic process;GO:0006874 intracellular calcium ion homeostasis;GO:0034220 monoatomic ion transmembrane transport;GO:0070588 calcium ion transmembrane transport;GO:0070509 calcium ion import", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K402-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M589-1", "uniprot_id": [ { "id": "F1M589_RAT", "url": "https://www.uniprot.org/uniprot/F1M589", "type": "external" } ], "mass": 103000.0, "length": 934, "protein_name": "Protein PML", "gene_name": "Pml", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Pml", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein PML", "protein_names_refseq": "", "tax_id": 10116, "disease": "acute promyelocytic leukemia (Disease Ontology:DOID:0060318); pre-eclampsia (Disease Ontology:DOID:10591); skin cancer (Disease Ontology:DOID:4159); clear cell renal cell carcinoma (Disease Ontology:DOID:4467); hepatocellular carcinoma (Disease Ontology:DOID:684); multiple myeloma (Disease Ontology:DOID:9538)", "pathway": " (rno:315713); (R-RNO-3108214); (R-RNO-3232142); (R-RNO-6804758); (R-RNO-8934593); (R-RNO-8948747)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0060090 molecular adaptor activity;GO:0003713 transcription coactivator activity;GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:1904816 positive regulation of protein localization to chromosome, telomeric region;GO:0044790 suppression of viral release by host;GO:0030578 PML body organization;GO:0006338 chromatin remodeling;GO:0008285 negative regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1M589-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MKC4-1", "uniprot_id": [ { "id": "A0A096MKC4_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MKC4", "type": "external" } ], "mass": 87018.0, "length": 755, "protein_name": "Transmembrane channel-like protein", "gene_name": "Tmc1", "organism": "Rat", "refseq_name": "transmembrane channel-like protein 1 isoform 2", "refseq_ac": [ { "id": "NP_001428430", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001428430", "type": "external" } ], "gene_names_uniprotkb": "Tmc1", "gene_names_refseq": "Tmc1", "protein_names_uniprotkb": "Transmembrane channel-like protein", "protein_names_refseq": "transmembrane channel-like gene family 1; transmembrane channel-like protein 1 isoform 2; transmembrane channel-like protein 1", "tax_id": 10116, "disease": "autosomal recessive nonsyndromic deafness 7 (Disease Ontology:DOID:0110520); autosomal dominant nonsyndromic deafness 36 (Disease Ontology:DOID:0110563); sensorineural hearing loss (Disease Ontology:DOID:10003)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005262 calcium channel activity;GO:0008381 mechanosensitive monoatomic ion channel activity;GO:0005245 voltage-gated calcium channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009897 external side of plasma membrane;GO:0032426 stereocilium tip;GO:0032420 stereocilium", "go_biological_process": "GO:0060005 vestibular reflex;GO:0050910 detection of mechanical stimulus involved in sensory perception of sound;GO:0070588 calcium ion transmembrane transport;GO:1903169 regulation of calcium ion transmembrane transport;GO:0060117 auditory receptor cell development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A096MKC4-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M7T1-1", "uniprot_id": [ { "id": "F1M7T1_RAT", "url": "https://www.uniprot.org/uniprot/F1M7T1", "type": "external" } ], "mass": 15032.0, "length": 129, "protein_name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "gene_name": "Ndufb4l1; Ndufb4l4; Ndufb4", "organism": "Rat", "refseq_name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4-like", "refseq_ac": [ { "id": "XP_038956055", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038956055", "type": "external" } ], "gene_names_uniprotkb": "Ndufb4l1; Ndufb4l4; Ndufb4; AABR07014298.1; LOC100361934; Ndufb4l4; Ndufb4", "gene_names_refseq": "Ndufb4l4", "protein_names_uniprotkb": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4; Complex I-B15; NADH-ubiquinone oxidoreductase B15 subunit", "protein_names_refseq": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4-like", "tax_id": 10116, "disease": "", "pathway": " (rno:100361934); (rno:288088)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045271 respiratory chain complex I", "go_biological_process": "GO:0022904 respiratory electron transport chain", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M7T1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JT46-1", "uniprot_id": [ { "id": "A0A0G2JT46_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JT46", "type": "external" } ], "mass": 61450.0, "length": 527, "protein_name": "Zinc finger protein 545", "gene_name": "Zfp82", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Zfp82", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger protein 545", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:100910231)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, 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0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.4.6", "url": 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"2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" }, { "id": "2.7.11.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.19", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.11.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.4", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.4.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.18", "type": "external" }, { "id": "3.1.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.24.-", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 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LOC679894; Pkd2", "gene_names_refseq": "Thoc2l", "protein_names_uniprotkb": "THO complex subunit 2", "protein_names_refseq": "similar to THO complex subunit 2 (Tho2)", "tax_id": 10116, "disease": "ciliopathy (Disease Ontology:DOID:0060340); polycystic kidney disease (Disease Ontology:DOID:0080322); polycystic kidney disease 2 (Disease Ontology:DOID:0110859); X-linked intellectual disability-short stature-overweight syndrome (Disease Ontology:DOID:0112056); intracranial aneurysm (Disease Ontology:DOID:10941); acute kidney failure (Disease Ontology:DOID:3021); retinal degeneration (Disease Ontology:DOID:8466); autosomal dominant polycystic kidney disease (Disease Ontology:DOID:898)", "pathway": " (rno:498328); (rno:679894)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D4A5F1", "ec_number_list": [], "go_molecular_function": "GO:0051371 muscle alpha-actinin binding;GO:0015271 outward rectifier potassium channel activity;GO:0003729 mRNA binding;GO:0005102 signaling receptor binding;GO:0005262 calcium channel activity", "go_cellular_component": "GO:0045180 basal cortex;GO:0034703 cation channel complex;GO:0098554 cytoplasmic side of endoplasmic reticulum membrane;GO:0002133 polycystin complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0090279 regulation of calcium ion import;GO:0003127 detection of nodal flow;GO:0072208 metanephric smooth muscle tissue development;GO:0072164 mesonephric tubule development;GO:0072218 metanephric ascending thin limb development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1LZ00-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LZA7-1", "uniprot_id": [ { "id": "F1LZA7_RAT", "url": "https://www.uniprot.org/uniprot/F1LZA7", "type": "external" } ], "mass": 88563.0, "length": 776, "protein_name": "Junctional cadherin complex regulator", "gene_name": "Jhy", "organism": "Rat", "refseq_name": "junctional cadherin complex regulator isoform 1", "refseq_ac": [ { "id": "NP_001416378", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001416378", "type": "external" } ], "gene_names_uniprotkb": "Jhy", "gene_names_refseq": "Jhy; RGD1309108", "protein_names_uniprotkb": "Junctional cadherin complex regulator", "protein_names_refseq": "jhy protein homolog; junctional cadherin complex regulator isoform 1; juvenile hydrocephalus; uncharacterized protein C11orf63 homolog", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0030154 cell differentiation;GO:0007420 brain development;GO:0044458 motile cilium assembly;GO:0035082 axoneme assembly;GO:0090175 regulation of establishment of planar polarity", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LZA7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LZJ4-1", "uniprot_id": [ { "id": "F1LZJ4_RAT", "url": "https://www.uniprot.org/uniprot/F1LZJ4", "type": "external" } ], "mass": 30590.0, "length": 277, "protein_name": "Putative hydroxypyruvate isomerase", "gene_name": "Hyi", "organism": "Rat", "refseq_name": "putative hydroxypyruvate isomerase", "refseq_ac": [ { "id": "NP_001385769", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385769", "type": "external" } ], "gene_names_uniprotkb": "Hyi; RGD1561416", "gene_names_refseq": "Hyi; RGD1561416", "protein_names_uniprotkb": "Putative hydroxypyruvate isomerase; 5.3.1.22", "protein_names_refseq": "putative hydroxypyruvate isomerase", "tax_id": 10116, "disease": "", "pathway": " (rno:500536)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.3.1.22", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.1.22", "type": "external" } ], "go_molecular_function": "GO:0008903 hydroxypyruvate isomerase activity", "go_cellular_component": "", "go_biological_process": "GO:0046487 glyoxylate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LZJ4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LZR4-1", "uniprot_id": [ { "id": "F1LZR4_RAT", "url": "https://www.uniprot.org/uniprot/F1LZR4", "type": "external" } ], "mass": 80626.0, "length": 718, "protein_name": "Interleukin-31 receptor subunit alpha", "gene_name": "Il31ra", "organism": "Rat", "refseq_name": "interleukin-31 receptor subunit alpha isoform X1", "refseq_ac": [ { "id": "XP_038959084", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038959084", "type": "external" } ], "gene_names_uniprotkb": "Il31ra", "gene_names_refseq": "Il31ra", "protein_names_uniprotkb": "Interleukin-31 receptor subunit alpha; GLM-R; Gp130-like monocyte receptor; ZcytoR17", "protein_names_refseq": "interleukin-31 receptor subunit alpha isoform X1", "tax_id": 10116, "disease": "primary localized cutaneous amyloidosis 2 (Disease Ontology:DOID:0080931)", "pathway": " (R-RNO-6788467)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1. Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019955 cytokine binding;GO:0004896 cytokine receptor activity", "go_cellular_component": "GO:0043235 receptor complex;GO:0009897 external side of plasma membrane;GO:0042734 presynaptic membrane", "go_biological_process": "GO:0002067 glandular epithelial cell differentiation;GO:0098542 defense response to other organism;GO:0008284 positive regulation of cell population proliferation;GO:0002438 acute inflammatory response to antigenic stimulus;GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LZR4-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M038-1", "uniprot_id": [ { "id": "F1M038_RAT", "url": "https://www.uniprot.org/uniprot/F1M038", "type": "external" } ], "mass": 38287.0, "length": 331, "protein_name": "Docking protein 6", "gene_name": "Dok6", "organism": "Rat", "refseq_name": "docking protein 6", "refseq_ac": [ { "id": "NP_001178872", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178872", "type": "external" } ], "gene_names_uniprotkb": "Dok6", "gene_names_refseq": "Dok6; RGD1564376", "protein_names_uniprotkb": "Docking protein 6", "protein_names_refseq": "docking protein 6", "tax_id": 10116, "disease": "", "pathway": " (rno:498898); (R-RNO-8853659)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "20078947", "class_list": "", "function": "Dok6 can promote neurite outgrowth induced by neurotrophin-3 stimulation through its C-terminus in TrkC-positive PC12 cells., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0035591 signaling adaptor activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1M038-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M078-1", "uniprot_id": [ { "id": "F1M078_RAT", "url": "https://www.uniprot.org/uniprot/F1M078", "type": "external" } ], "mass": 134499.0, "length": 1198, "protein_name": "Zinc finger protein 804A", "gene_name": "Zfp804a", "organism": "Rat", "refseq_name": "zinc finger protein 804A", "refseq_ac": [ { "id": "NP_001416774", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001416774", "type": "external" } ], "gene_names_uniprotkb": "Zfp804a", "gene_names_refseq": "RGD1305239; Zfp804a; Znf804a", "protein_names_uniprotkb": "Zinc finger protein 804A", "protein_names_refseq": "zinc finger protein 804A", "tax_id": 10116, "disease": "schizophrenia (Disease Ontology:DOID:5419)", "pathway": " (rno:295695)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "22384243;26148198", "class_list": "", "function": "These data implicate ZFP804A in growth cone function and neurite elongation. Publication Status: Online-Only, [RefSeq, PubMed]; ZNF804a regulates expression of the schizophrenia-associated genes PRSS16, COMT, PDE4B, and DRD2, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, 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RGD1562431", "gene_names_refseq": "Pced1bl1", "protein_names_uniprotkb": "PC-esterase domain containing 1B like 1", "protein_names_refseq": "PC-esterase domain-containing protein 1B-like", "tax_id": 10116, "disease": "", "pathway": " (rno:316465)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M6L4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M6N0-1", "uniprot_id": [ { "id": "F1M6N0_RAT", "url": "https://www.uniprot.org/uniprot/F1M6N0", "type": "external" } ], "mass": 31660.0, "length": 306, "protein_name": "KPRP N-terminal and LCE C-terminal like protein", "gene_name": "Kplce", "organism": "Rat", "refseq_name": "protein KPLCE", "refseq_ac": [ { "id": "NP_001406451", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001406451", "type": "external" } ], "gene_names_uniprotkb": "Kplce; LOC686143", "gene_names_refseq": "Kplce", "protein_names_uniprotkb": "KPRP N-terminal and LCE C-terminal like protein", "protein_names_refseq": "protein KPLCE; skin-specific protein 32", "tax_id": 10116, "disease": "", "pathway": " (rno:686143)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M6N0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M6Z0-1", "uniprot_id": [ { "id": "F1M6Z0_RAT", "url": "https://www.uniprot.org/uniprot/F1M6Z0", "type": "external" } ], "mass": 148744.0, "length": 1354, "protein_name": "Tripartite motif-containing protein 66", "gene_name": "Trim66", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Trim66", "gene_names_refseq": "", "protein_names_uniprotkb": "Tripartite motif-containing protein 66", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:361623)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May function as transcription repressor; The repressive effects are mediated, at least in part, by recruitment of deacetylase activity. May play a role as negative regulator of postmeiotic genes acting through CBX3 complex formation and centromere association., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0010369 chromocenter;GO:0005654 nucleoplasm", "go_biological_process": "GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M6Z0-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M706-1", "uniprot_id": [ { "id": "F1M706_RAT", "url": "https://www.uniprot.org/uniprot/F1M706", "type": "external" } ], "mass": 12258.0, "length": 105, "protein_name": "60S ribosomal protein L36", "gene_name": "Rpl36l5", "organism": "Rat", "refseq_name": "large ribosomal subunit protein eL36-like", "refseq_ac": [ { "id": "XP_038945785", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038945785", "type": "external" } ], "gene_names_uniprotkb": "Rpl36l5; AABR07072272.1; LOC100360439", "gene_names_refseq": "Rpl36l5", "protein_names_uniprotkb": "60S ribosomal protein L36", "protein_names_refseq": "large ribosomal subunit protein eL36-like", "tax_id": 10116, "disease": "", "pathway": " (rno:100360439); (R-RNO-156827); (R-RNO-1799339); (R-RNO-6791226); (R-RNO-72689); (R-RNO-72706); (R-RNO-975956); (R-RNO-975957); (R-RNO-9954709); (R-RNO-9954714); (R-RNO-9954716)", "pathway_count": 11, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M706-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M711-1", "uniprot_id": [ { "id": "F1M711_RAT", "url": "https://www.uniprot.org/uniprot/F1M711", "type": "external" } ], "mass": 125245.0, "length": 1120, "protein_name": "Pecanex-like protein", "gene_name": "AABR07064804.1; Pcnx4", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "AABR07064804.1; Pcnx4; AABR07064804.1; Pcnx4", "gene_names_refseq": "", "protein_names_uniprotkb": "Pecanex-like protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M711-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M759-1", "uniprot_id": [ { "id": "F1M759_RAT", "url": "https://www.uniprot.org/uniprot/F1M759", "type": "external" } ], "mass": 39369.0, "length": 359, "protein_name": "Prickle planar cell polarity protein 4", "gene_name": "Prickle4", "organism": "Rat", "refseq_name": "prickle-like protein 4 isoform X1", "refseq_ac": [ { "id": "XP_038940418", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038940418", "type": "external" } ], "gene_names_uniprotkb": "Prickle4", "gene_names_refseq": "Prickle4; RGD1563979", "protein_names_uniprotkb": "Prickle planar cell polarity protein 4", "protein_names_refseq": "prickle-like protein 4 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:316212)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051371 muscle alpha-actinin binding;GO:0003779 actin binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005912 adherens junction;GO:0001725 stress fiber;GO:0030018 Z disc;GO:0031941 filamentous actin", "go_biological_process": "GO:0007507 heart development;GO:0030036 actin cytoskeleton organization;GO:0061061 muscle structure development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M759-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M7A9-1", "uniprot_id": [ { "id": "F1M7A9_RAT", "url": "https://www.uniprot.org/uniprot/F1M7A9", "type": "external" } ], "mass": 24941.0, "length": 219, "protein_name": "Large ribosomal subunit protein uL6", "gene_name": "AABR07026048.1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "AABR07026048.1", "gene_names_refseq": "", "protein_names_uniprotkb": "Large ribosomal subunit protein uL6; 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[provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M8Z7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M990-1", "uniprot_id": [ { "id": "F1M990_RAT", "url": "https://www.uniprot.org/uniprot/F1M990", "type": "external" } ], "mass": 9720.0, "length": 79, "protein_name": "Cyclin-dependent kinases regulatory subunit", "gene_name": "Cks1l", "organism": "Rat", "refseq_name": "CDC28 protein kinase regulatory subunit 1-like", "refseq_ac": [ { "id": "NP_001395729", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001395729", "type": "external" } ], "gene_names_uniprotkb": "Cks1l; AABR07049223.1", "gene_names_refseq": "Cks1bp6; Cks1l", "protein_names_uniprotkb": "Cyclin-dependent kinases regulatory subunit", "protein_names_refseq": "CDC28 protein kinase 1B-like; CDC28 protein kinase regulatory subunit 1-like; CDC28 protein kinase regulatory subunit 1B pseudogene 6; cyclin-dependent kinases regulatory subunit 1", "tax_id": 10116, "disease": "", "pathway": " (rno:681162)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22017545", "class_list": "", "function": "Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function., [UniProtKB, UniProtKB, UniProtKB]; Skp2 and Cks1 are up-regulated by the TNFalpha-RelB/p52 pathway in the early stages of renal damage and are collaboratively involved in down-regulation of p27 in proliferative tubular dilation and the progression of chronic nephropathy., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0042393 histone binding;GO:0043130 ubiquitin binding;GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity", "go_cellular_component": "GO:0019005 SCF ubiquitin ligase complex;GO:0000307 cyclin-dependent protein kinase holoenzyme complex", "go_biological_process": "GO:0044772 mitotic cell cycle phase transition;GO:0051301 cell division;GO:0007346 regulation of mitotic cell cycle;GO:0048144 fibroblast proliferation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1M990-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M9P7-1", "uniprot_id": [ { "id": "F1M9P7_RAT", "url": "https://www.uniprot.org/uniprot/F1M9P7", "type": "external" } ], "mass": 77495.0, "length": 686, "protein_name": "MAM domain-containing protein 2", "gene_name": "Mamdc2", "organism": "Rat", "refseq_name": "MAM domain-containing protein 2 precursor", "refseq_ac": [ { "id": "NP_001094166", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094166", "type": "external" } ], "gene_names_uniprotkb": "Mamdc2", "gene_names_refseq": "Mamdc2", "protein_names_uniprotkb": "MAM domain-containing protein 2; MAM domain-containing proteoglycan", "protein_names_refseq": "MAM domain-containing protein 2 precursor; MAM domain-containing protein 2", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005539 glycosaminoglycan binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0031012 extracellular matrix;GO:0005614 interstitial matrix", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M9P7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M9Q3-1", "uniprot_id": [ { "id": "F1M9Q3_RAT", "url": "https://www.uniprot.org/uniprot/F1M9Q3", "type": "external" } ], "mass": 201938.0, "length": 1798, "protein_name": "E3 ubiquitin-protein ligase listerin", "gene_name": "Ltn1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ltn1", "gene_names_refseq": "", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase listerin; 2.3.2.27; RING-type E3 ubiquitin transferase listerin", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-983168); (R-RNO-9954709)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "2.3.2.32", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.32", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "2.3.2.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.24", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity;GO:0043023 ribosomal large subunit binding", "go_cellular_component": "GO:0005829 cytosol;GO:0022626 cytosolic ribosome;GO:1990112 RQC complex", "go_biological_process": "GO:0072344 rescue of stalled ribosome;GO:0051865 protein autoubiquitination;GO:1990116 ribosome-associated ubiquitin-dependent protein catabolic process;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M9Q3-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M9V4-1", "uniprot_id": [ { "id": "F1M9V4_RAT", "url": "https://www.uniprot.org/uniprot/F1M9V4", "type": "external" } ], "mass": 226049.0, "length": 2055, "protein_name": "KIAA1210 homolog", "gene_name": "Kiaa1210", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Kiaa1210; 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transforming growth factor-beta receptor type 3-like protein precursor", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005024 transforming growth factor beta receptor activity;GO:0005114 type II transforming growth factor beta receptor binding;GO:0005539 glycosaminoglycan binding", "go_cellular_component": "", "go_biological_process": "GO:0017015 regulation of transforming growth factor beta receptor signaling pathway;GO:0016477 cell migration;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0001837 epithelial to mesenchymal transition", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R3W3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R4D3-1", "uniprot_id": [ { "id": "M0R4D3_RAT", "url": "https://www.uniprot.org/uniprot/M0R4D3", "type": "external" } ], "mass": 60777.0, "length": 538, "protein_name": "Butyrophilin-like 4", "gene_name": "Btnl4", "organism": "Rat", "refseq_name": "butyrophilin-like 9 precursor", "refseq_ac": [ { "id": "NP_001159826", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001159826", "type": "external" } ], "gene_names_uniprotkb": "Btnl4; 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coiled-coil domain-containing protein 166", "tax_id": 10116, "disease": "", "pathway": " (rno:680799)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R4R5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R4T2-1", "uniprot_id": [ { "id": "M0R4T2_RAT", "url": "https://www.uniprot.org/uniprot/M0R4T2", "type": "external" } ], "mass": 135189.0, "length": 1182, "protein_name": "NLR family, pyrin domain containing 1B", "gene_name": "Nlrp1b", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Nlrp1b", "gene_names_refseq": "", "protein_names_uniprotkb": "NLR family, pyrin domain containing 1B", "protein_names_refseq": "", "tax_id": 10116, "disease": "vitiligo (Disease Ontology:DOID:12306)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Constitutes the active part of the Nlrp1a inflammasome. In absence of pathogens and other damage-associated signals, interacts with the N-terminal part of Nlrp1a (NACHT, LRR and PYD domains-containing protein 1a, N-terminus), preventing activation of the Nlrp1a inflammasome. In response to pathogen-associated signals, the N-terminal part of Nlrp1a is degraded by the proteasome, releasing this form, which polymerizes to form the Nlrp1a inflammasome complex: the Nlrp1a inflammasome complex then directly recruits pro-caspase-1 (proCASP1) and promotes caspase-1 (CASP1) activation, leading to gasdermin-D (GSDMD) cleavage and subsequent pyroptosis., [UniProtKB, UniProtKB]; Constitutes the precursor of the Nlrp1a inflammasome, which mediates autoproteolytic processing within the FIIND domain to generate the N-terminal and C-terminal parts, which are associated non-covalently in absence of pathogens and other damage-associated signals., [UniProtKB, UniProtKB]; Regulatory part that prevents formation of the Nlrp1a inflammasome: in absence of pathogens and other damage-associated signals, interacts with the C-terminal part of Nlrp1a (NACHT, LRR and PYD domains-containing protein 1a, C-terminus), preventing activation of the Nlrp1a inflammasome. In response to pathogen-associated signals, this part is ubiquitinated by the N-end rule pathway and degraded by the proteasome, releasing the cleaved C-terminal part of the protein, which polymerizes and forms the Nlrp1a inflammasome., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0097110 scaffold protein binding;GO:0008233 peptidase activity;GO:0038187 pattern recognition receptor activity;GO:0140608 cysteine-type endopeptidase activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0043025 neuronal cell body;GO:0072559 NLRP3 inflammasome complex", "go_biological_process": "GO:0006508 proteolysis;GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:0042981 regulation of apoptotic process;GO:0097193 intrinsic apoptotic signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R4T2-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R593-1", "uniprot_id": [ { "id": "M0R593_RAT", "url": "https://www.uniprot.org/uniprot/M0R593", "type": "external" } ], "mass": 31461.0, "length": 272, "protein_name": "Uncharacterized LOC108350036", "gene_name": "LOC108350036", "organism": "Rat", "refseq_name": "uncharacterized protein LOC108350036 isoform X1", "refseq_ac": [ { "id": "XP_063138970", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063138970", "type": "external" } ], "gene_names_uniprotkb": "LOC108350036", "gene_names_refseq": "LOC108350036", "protein_names_uniprotkb": "Uncharacterized LOC108350036", "protein_names_refseq": "uncharacterized protein LOC108350036 isoform X1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R593-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R5D7-1", "uniprot_id": [ { "id": "M0R5D7_RAT", "url": "https://www.uniprot.org/uniprot/M0R5D7", "type": "external" } ], "mass": 14543.0, "length": 134, "protein_name": "Psoriasis susceptibility 1 candidate 2", "gene_name": "Psors1c2", "organism": "Rat", "refseq_name": "psoriasis susceptibility 1 candidate gene 2 protein precursor", "refseq_ac": [ { "id": "NP_001159488", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001159488", "type": "external" } ], "gene_names_uniprotkb": "Psors1c2", "gene_names_refseq": "Pcg; Psors1c2; Spr1", "protein_names_uniprotkb": "Psoriasis susceptibility 1 candidate 2", "protein_names_refseq": "psoriasis susceptibility 1 candidate gene 2 protein precursor", "tax_id": 10116, "disease": "", "pathway": " (rno:686254)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R5D7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R5G5-1", "uniprot_id": [ { "id": "M0R5G5_RAT", "url": "https://www.uniprot.org/uniprot/M0R5G5", "type": "external" } ], "mass": 271975.0, "length": 2457, "protein_name": "Polycystin-1-like protein 2", "gene_name": "Pkd1l2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Pkd1l2", "gene_names_refseq": "", "protein_names_uniprotkb": "Polycystin-1-like protein 2; PC1-like 2 protein; Polycystic kidney disease protein 1-like 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May function as a G-protein-coupled receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 2, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005262 calcium channel activity;GO:0005509 calcium ion binding;GO:0030246 carbohydrate binding", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0050982 detection of mechanical stimulus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R5G5-1", "record_type": "protein", "filter_code": "0000000.1000000.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R5Z6-1", "uniprot_id": [ { "id": "M0R5Z6_RAT", "url": "https://www.uniprot.org/uniprot/M0R5Z6", "type": "external" } ], "mass": 174566.0, "length": 1775, "protein_name": "Melanoma-associated antigen D1", "gene_name": "AABR07037520.1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "AABR07037520.1; Tro", "gene_names_refseq": "", "protein_names_uniprotkb": "Melanoma-associated antigen D1; MAGE-D1 antigen; Neurotrophin receptor-interacting MAGE homolog", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0030308 negative regulation of cell growth", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R5Z6-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R657-1", "uniprot_id": [ { "id": "M0R657_RAT", "url": "https://www.uniprot.org/uniprot/M0R657", "type": "external" } ], "mass": 30609.0, "length": 264, "protein_name": "Y-linked testis-specific protein 1-like", "gene_name": "LOC134486240", "organism": "Rat", "refseq_name": "Y-linked testis-specific protein 1-like", "refseq_ac": [ { "id": "XP_063141231", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063141231", "type": "external" } ], "gene_names_uniprotkb": "LOC134486240; LOC108353098; LOC134478819; LOC134484539; LOC134486252", "gene_names_refseq": "LOC134486240", "protein_names_uniprotkb": "Y-linked testis-specific protein 1-like", "protein_names_refseq": "Y-linked testis-specific protein 1-like", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8I6AX36", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0007276 gamete generation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R657-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R665-1", "uniprot_id": [ { "id": "M0R665_RAT", "url": "https://www.uniprot.org/uniprot/M0R665", "type": "external" } ], "mass": 23314.0, "length": 211, "protein_name": "Large ribosomal subunit protein eL29", "gene_name": "LOC120093247", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LOC120093247", "gene_names_refseq": "", "protein_names_uniprotkb": "Large ribosomal subunit protein eL29; 60S ribosomal protein L29", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:120093247); (R-RNO-156827); (R-RNO-1799339); (R-RNO-6791226); (R-RNO-72689); (R-RNO-72706); (R-RNO-975956); (R-RNO-975957); (R-RNO-9954709); (R-RNO-9954714); (R-RNO-9954716)", "pathway_count": 11, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R665-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R6H0-1", "uniprot_id": [ { "id": "M0R6H0_RAT", "url": "https://www.uniprot.org/uniprot/M0R6H0", "type": "external" } ], "mass": 41889.0, "length": 357, "protein_name": "LINE-1 retrotransposable element ORF1 protein", "gene_name": "AABR07004232.1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "AABR07004232.1", "gene_names_refseq": "", "protein_names_uniprotkb": "LINE-1 retrotransposable element ORF1 protein; LINE retrotransposable element 1; LINE1 retrotransposable element 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Nucleic acid-binding protein which is essential for retrotransposition of LINE-1 elements in the genome. Functions as a nucleic acid chaperone binding its own transcript and therefore preferentially mobilizing the transcript from which they are encoded., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000166 nucleotide binding;GO:0003727 single-stranded RNA binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0010494 cytoplasmic stress granule;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0032197 retrotransposition", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R6H0-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R6P4-1", "uniprot_id": [ { "id": "M0R6P4_RAT", "url": "https://www.uniprot.org/uniprot/M0R6P4", "type": "external" } ], "mass": 34858.0, "length": 314, "protein_name": "Olfactory receptor", "gene_name": "Or5p76b", "organism": "Rat", "refseq_name": "olfactory receptor Olr278", "refseq_ac": [ { "id": "NP_001000730", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000730", "type": "external" } ], "gene_names_uniprotkb": "Or5p76b", "gene_names_refseq": "Olr278; Or5p76b", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 278; olfactory receptor Olr278; olfactory receptor gene Olr278", "tax_id": 10116, "disease": "", "pathway": " (rno:404986)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"refseq_ac": [ { "id": "NP_001414437", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414437", "type": "external" } ], "gene_names_uniprotkb": "Tbc1d16", "gene_names_refseq": "Tbc1d16", "protein_names_uniprotkb": "TBC1 domain family, member 16", "protein_names_refseq": "TBC1 domain family member 16", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-8854214)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, 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"2.7.11.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.4", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.4.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.18", "type": "external" }, { "id": "3.1.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.24.-", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "", "go_biological_process": "GO:0042149 cellular response to glucose starvation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "M0R777-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R7F3-1", "uniprot_id": [ { "id": "M0R7F3_RAT", "url": "https://www.uniprot.org/uniprot/M0R7F3", "type": "external" } ], "mass": 55329.0, "length": 502, "protein_name": "Wiskott-Aldrich syndrome protein family member", "gene_name": "Wasf3", "organism": "Rat", "refseq_name": "actin-binding protein WASF3", "refseq_ac": [ { "id": "NP_001414083", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414083", "type": "external" } ], "gene_names_uniprotkb": "Wasf3", "gene_names_refseq": "Wasf3", "protein_names_uniprotkb": "Wiskott-Aldrich syndrome 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The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0034237 protein kinase A regulatory subunit binding;GO:0071933 Arp2/3 complex binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005856 cytoskeleton;GO:0030027 lamellipodium;GO:0098794 postsynapse;GO:0031209 SCAR complex", "go_biological_process": "GO:0098885 modification of postsynaptic actin cytoskeleton;GO:0030036 actin cytoskeleton organization;GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation;GO:0030032 lamellipodium assembly;GO:0014003 oligodendrocyte development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R7F3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R7L1-1", "uniprot_id": [ { "id": "M0R7L1_RAT", "url": "https://www.uniprot.org/uniprot/M0R7L1", "type": "external" } ], "mass": 45881.0, "length": 399, "protein_name": "Lipase", "gene_name": "Lipj", "organism": "Rat", "refseq_name": "tear acid lipase-like protein", "refseq_ac": [ { "id": "XP_006231366", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006231366", "type": "external" } ], "gene_names_uniprotkb": "Lipj; LOC100360690", "gene_names_refseq": "Lipj", "protein_names_uniprotkb": "Lipase", "protein_names_refseq": "tear acid lipase-like protein", "tax_id": 10116, "disease": "", "pathway": " (rno:100360690)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.-", "type": "external" }, { "id": "3.1.1.71", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.71", "type": "external" }, { "id": "3.1.1.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.13", "type": "external" } ], "go_molecular_function": "GO:0004771 sterol ester esterase activity", "go_cellular_component": "GO:0005811 lipid droplet", "go_biological_process": "GO:0016042 lipid catabolic process;GO:0016125 sterol metabolic process;GO:0019915 lipid storage", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R7L1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R7T6-1", "uniprot_id": [ { "id": "RBM24_RAT", "url": "https://www.uniprot.org/uniprot/M0R7T6", "type": "external" } ], "mass": 24852.0, "length": 236, "protein_name": "RNA-binding protein 24", "gene_name": "Rbm24", "organism": "Rat", "refseq_name": "RNA-binding protein 24", "refseq_ac": [ { "id": "NP_001178029", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178029", "type": "external" } ], "gene_names_uniprotkb": "Rbm24", "gene_names_refseq": "Rbm24", "protein_names_uniprotkb": "RNA-binding protein 24; RNA-binding motif protein 24", "protein_names_refseq": "RNA-binding protein 24", "tax_id": 10116, "disease": "microphthalmia (Disease Ontology:DOID:10629); dilated cardiomyopathy (Disease Ontology:DOID:12930); cataract (Disease Ontology:DOID:83)", "pathway": " (rno:690139)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "27289039", "class_list": "", "function": "Multifunctional RNA-binding protein involved in the regulation of pre-mRNA splicing, mRNA stability and mRNA translation important for cell fate decision and differentiation (PubMed:27289039). Plays a major role in pre-mRNA alternative splicing regulation (By similarity). Mediates preferentially muscle-specific exon inclusion in numerous mRNAs important for striated cardiac and skeletal muscle cell differentiation (By similarity). Binds to intronic splicing enhancer (ISE) composed of stretches of GU-rich motifs localized in flanking intron of exon that will be included by alternative splicing (By similarity). Involved in embryonic stem cell (ESC) transition to cardiac cell differentiation by promoting pre-mRNA alternative splicing events of several pluripotency and/or differentiation genes (By similarity). Plays a role in the regulation of mRNA stability (By similarity). Binds to 3'-untranslated region (UTR) AU-rich elements in target transcripts, such as CDKN1A and MYOG, leading to maintain their stabilities (By similarity). Involved in myogenic differentiation by regulating MYOG levels (By similarity). Binds to multiple regions in the mRNA 3'-UTR of TP63 isoform 2, hence inducing its destabilization (By similarity). Also promotes the destabilization of the CHRM2 mRNA via its binding to a region in the coding sequence (By similarity). Plays a role in the regulation of mRNA translation (By similarity). Mediates repression of p53/TP53 mRNA translation through its binding to U-rich element in the 3'-UTR, hence preventing EIF4E from binding to p53/TP53 mRNA and translation initiation (By similarity). Binds to a huge amount of mRNAs (By similarity). Required for embryonic heart development, sarcomer and M-band formation in striated muscles (By similarity). Together with RBM20, promotes the expression of short isoforms of PDLIM5/ENH in cardiomyocytes (PubMed:27289039)., [UniProtKB, PubMed, UniProtKB, UniProtKB]; Results suggest that, in healthy conditions, RBM20 and RBM24 cooperate to promote the expression of short ENH isoforms., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:1990825 sequence-specific mRNA binding;GO:0097157 pre-mRNA intronic binding;GO:0003730 mRNA 3'-UTR binding;GO:1990715 mRNA CDS binding;GO:0035925 mRNA 3'-UTR AU-rich region binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0010831 positive regulation of myotube differentiation;GO:0010830 regulation of myotube differentiation;GO:0006397 mRNA processing;GO:0030154 cell differentiation;GO:0048255 mRNA stabilization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "M0R7T6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R8E3-1", "uniprot_id": [ { "id": "M0R8E3_RAT", "url": "https://www.uniprot.org/uniprot/M0R8E3", "type": "external" } ], "mass": 30938.0, "length": 277, "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "ENSRNOG00000069479", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ENSRNOG00000069479", "gene_names_refseq": "", "protein_names_uniprotkb": "Peptidase S1 domain-containing protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-1592389); (R-RNO-381426)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0030141 secretory granule", "go_biological_process": "GO:0003073 regulation of systemic arterial blood pressure;GO:0031638 zymogen activation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R8E3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R950-1", "uniprot_id": [ { "id": "M0R950_RAT", "url": "https://www.uniprot.org/uniprot/M0R950", "type": "external" } ], "mass": 86315.0, "length": 791, "protein_name": "ATR interacting protein", "gene_name": "Atrip", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Atrip", "gene_names_refseq": "", "protein_names_uniprotkb": "ATR interacting protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "Seckel syndrome (Disease Ontology:DOID:0050569)", "pathway": " (R-RNO-176187); (R-RNO-5685938); (R-RNO-5693607); (R-RNO-6783310); (R-RNO-6804756); (R-RNO-69473)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0070530 K63-linked polyubiquitin modification-dependent protein binding", "go_cellular_component": "GO:0005654 nucleoplasm", "go_biological_process": "GO:0000077 DNA damage checkpoint signaling;GO:0006281 DNA repair", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R950-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R994-1", "uniprot_id": [ { "id": "M0R994_RAT", "url": "https://www.uniprot.org/uniprot/M0R994", "type": "external" } ], "mass": 35678.0, "length": 314, "protein_name": "Olfactory receptor", "gene_name": "Or5d14l1", "organism": "Rat", "refseq_name": "rCG27063-like", "refseq_ac": [ { "id": "NP_001396239", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001396239", "type": "external" } ], "gene_names_uniprotkb": "Or5d14l1; LOC100365887", "gene_names_refseq": "Or5d14l1", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 5D14; rCG27063-like", "tax_id": 10116, "disease": "", "pathway": " (rno:100365887)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R994-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R9F7-1", "uniprot_id": [ { "id": "M0R9F7_RAT", "url": "https://www.uniprot.org/uniprot/M0R9F7", "type": "external" } ], "mass": 52392.0, "length": 519, "protein_name": "Macrophage receptor with collagenous structure", "gene_name": "Marco", "organism": "Rat", "refseq_name": "macrophage receptor MARCO", "refseq_ac": [ { "id": "NP_001102481", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102481", "type": "external" } ], "gene_names_uniprotkb": "Marco", "gene_names_refseq": "Marco", "protein_names_uniprotkb": "Macrophage receptor with collagenous structure", "protein_names_refseq": "macrophage receptor MARCO", "tax_id": 10116, "disease": "meningococcal meningitis (Disease Ontology:DOID:0080176); silicosis (Disease Ontology:DOID:10325); respiratory syncytial virus infectious disease (Disease Ontology:DOID:1273); pulmonary tuberculosis (Disease Ontology:DOID:2957)", "pathway": " (rno:367391)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "15987691;30391304;31344978", "class_list": "", "function": "Polyguanylic acid reduced MARCO expression and inhibition of MARCO regulated the expression of silica-induced epithelial-mesenchymal transition markers in rat silicosis model., [RefSeq, PubMed]; SR-MARCO could be the scavenger receptor responsible for the adhesion of astrocytes and microglia to Abeta, [RefSeq, PubMed]; The molecular docking revealed that S-allyl-mercapto-glutathione interacting with Colec12, MARCO (class A), and SCARB1 (class B) scavenger receptors in in vitro tests demonstrates a direct stimulation of immunoglobulin secretion by S-allylmercaptoglutathione (GSSA) in CD19+ B lymphocytes. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001540 amyloid-beta binding;GO:0001664 G protein-coupled receptor binding;GO:0038024 cargo receptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0006897 endocytosis;GO:0006911 phagocytosis, engulfment;GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0030198 extracellular matrix organization;GO:0070374 positive regulation of ERK1 and ERK2 cascade", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "M0R9F7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R9G0-1", "uniprot_id": [ { "id": "M0R9G0_RAT", "url": "https://www.uniprot.org/uniprot/M0R9G0", "type": "external" } ], "mass": 35763.0, "length": 319, "protein_name": "Olfactory receptor family 56 subfamily B member 2K", "gene_name": "Or56b2k", "organism": "Rat", "refseq_name": "olfactory receptor Olr167", "refseq_ac": [ { "id": "NP_001000173", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000173", "type": "external" } ], "gene_names_uniprotkb": "Or56b2k", "gene_names_refseq": "Olr167; Or56b2k", "protein_names_uniprotkb": "Olfactory receptor family 56 subfamily B member 2K", "protein_names_refseq": "olfactory receptor 167; olfactory receptor Olr167; olfactory receptor gene Olr167; putative olfactory receptor 56B2-like", "tax_id": 10116, "disease": "", "pathway": " (rno:293314)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0071396 cellular response to lipid", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R9G0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R9P2-1", "uniprot_id": [ { "id": "M0R9P2_RAT", "url": "https://www.uniprot.org/uniprot/M0R9P2", "type": "external" } ], "mass": 34545.0, "length": 305, "protein_name": "Olfactory receptor", "gene_name": "Or5ac22", "organism": "Rat", "refseq_name": "olfactory receptor Olr1532", "refseq_ac": [ { "id": "NP_001001103", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001103", "type": "external" } ], "gene_names_uniprotkb": "Or5ac22", "gene_names_refseq": "Olr1532; Or5ac22", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1532; olfactory receptor Olr1532; olfactory receptor gene Olr1532", "tax_id": 10116, "disease": "", "pathway": " (rno:405999)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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Also functions as a pH-independent carnitine efflux transporter (By similarity)., [UniProtKB, UniProtKB, PubMed]; Extracellular pH-and Na(+)-sensitive low-affinity creatine transporter. 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In pancreatic beta-cells, inhibits insulin secretion probably by interacting with and regulating STX1A and STX4, key t-SNARE proteins involved in the fusion of insulin granules to the plasma membrane. Also plays a role in neurotransmitter release by inhibiting basal acetylcholine release from axon terminals and by preventing synaptic fatigue upon repetitive stimulation. Promotes as well axonal outgrowth., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0045159 myosin II binding;GO:0005096 GTPase activator activity;GO:0019905 syntaxin binding", "go_cellular_component": "GO:0098992 neuronal dense core vesicle;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0031594 neuromuscular junction", "go_biological_process": "GO:0050714 positive regulation of protein secretion;GO:0042593 glucose homeostasis;GO:0046676 negative regulation of insulin secretion;GO:0006887 exocytosis;GO:0006893 Golgi to plasma membrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZU84-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZUD9-1", "uniprot_id": [ { "id": "D3ZUD9_RAT", "url": "https://www.uniprot.org/uniprot/D3ZUD9", "type": "external" } ], "mass": 15509.0, "length": 133, "protein_name": "Transmembrane protein 60", "gene_name": "Tmem60", "organism": "Rat", "refseq_name": "transmembrane protein 60", "refseq_ac": [ { "id": "NP_001178539", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178539", "type": "external" } ], "gene_names_uniprotkb": "Tmem60", "gene_names_refseq": "RGD1308939; 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Or9g20", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 459; olfactory receptor Olr459; olfactory receptor gene Olr459", "tax_id": 10116, "disease": "", "pathway": " (rno:295729)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZVQ4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZWP6-1", "uniprot_id": [ { "id": "D3ZWP6_RAT", "url": "https://www.uniprot.org/uniprot/D3ZWP6", "type": "external" } ], "mass": 211604.0, "length": 1894, "protein_name": "Plexin-A2", "gene_name": "Plxna2", "organism": "Rat", "refseq_name": "plexin-A2 precursor", "refseq_ac": [ { "id": "NP_001099458", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099458", "type": "external" } ], "gene_names_uniprotkb": "Plxna2", "gene_names_refseq": "Plxna2", "protein_names_uniprotkb": "Plexin-A2", "protein_names_refseq": "plexin-A2 precursor", "tax_id": 10116, "disease": "", "pathway": " (rno:289392); (R-RNO-399954); (R-RNO-399955); (R-RNO-399956)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "34474008;37068642;38843836", "class_list": "", "function": "Coreceptor for SEMA3A and SEMA6A. Necessary for signaling by SEMA6A and class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm., [UniProtKB, UniProtKB]; MiR-145a-5p/Plexin-A2 promotes the migration of OECs and transplantation of miR-145a-5p engineered OECs enhances the functional recovery in rats with SCI., [RefSeq, PubMed]; PLXNA2 knockdown promotes M2 microglia polarization through mTOR/STAT3 signaling to improve functional recovery in rats after cerebral ischemia/reperfusion injury., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, 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"gene_name": "G3bp1", "organism": "Rat", "refseq_name": "ras GTPase-activating protein-binding protein 1", "refseq_ac": [ { "id": "NP_598249", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_598249", "type": "external" } ], "gene_names_uniprotkb": "G3bp1", "gene_names_refseq": "G3bp1; G3bp; RGD1310666", "protein_names_uniprotkb": "Ras GTPase-activating protein-binding protein 1; 3.6.4.12; 3.6.4.13", "protein_names_refseq": "GTPase activating protein (SH3 domain) binding protein 1; Ras-GTPase-activating protein SH3-domain binding protein 1; ras GTPase-activating protein-binding protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:171092)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "20392851;22673903;33065005;36450665;37442236;38843836", "class_list": "", "function": "A Ca(2+)-Dependent Switch Activates Axonal Casein Kinase 2alpha Translation and Drives G3BP1 Granule Disassembly for Axon Regeneration., [RefSeq, PubMed]; G3BP1 coordinates lysophagy activity to protect against compression-induced cell ferroptosis during intervertebral disc degeneration., [RefSeq, PubMed]; The translation initiating factor eIF4E and arginine methylation underlie G3BP1 function in dendritic spine development of neurons., [RefSeq, PubMed]; Two related proteins found in association with nsP4 at both times of infection, GTPase-activating protein (SH3 domain) binding protein 1 (G3BP1) and G3BP2 were also previously identified as associated with sindbis virus nsP2 and nsP3., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, 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"https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "7.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.1.3.1", "url": 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"url": "https://www.uniprot.org/uniprot/D4A050", "type": "external" } ], "mass": 149649.0, "length": 1310, "protein_name": "Protein broad-minded", "gene_name": "Tbc1d32", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Tbc1d32; LOC100359595", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein broad-minded; TBC1 domain family member 32", "protein_names_refseq": "", "tax_id": 10116, "disease": "visceral heterotaxy (Disease Ontology:DOID:0050545); Meckel syndrome (Disease Ontology:DOID:0050778); orofaciodigital syndrome IX (Disease Ontology:DOID:0060382); VACTERL association (Disease Ontology:DOID:14679); Bardet-Biedl syndrome (Disease Ontology:DOID:1935)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "16641100", "class_list": "", "function": "Required for high-level Shh responses in the developing neural tube. Together with CDK20, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to Shh signaling., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005929 cilium", "go_biological_process": "GO:0007507 heart development;GO:0001822 kidney development;GO:0060041 retina development in camera-type eye;GO:0021915 neural tube development;GO:0060271 cilium assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A050-1", "record_type": "protein", "filter_code": "0000000.0000110.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A0S2-1", "uniprot_id": [ { "id": "D4A0S2_RAT", "url": "https://www.uniprot.org/uniprot/D4A0S2", "type": "external" } ], "mass": 28925.0, "length": 260, "protein_name": "Uncharacterized protein", "gene_name": "AABR07026929.1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "AABR07026929.1", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A0S2-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A0W1-1", "uniprot_id": [ { "id": "D4A0W1_RAT", "url": "https://www.uniprot.org/uniprot/D4A0W1", "type": "external" } ], "mass": 20117.0, "length": 183, "protein_name": "ER membrane protein complex subunit 4", "gene_name": "Emc4", "organism": "Rat", "refseq_name": "ER membrane protein complex subunit 4", "refseq_ac": [ { "id": "NP_001099965", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099965", "type": "external" } ], "gene_names_uniprotkb": "Emc4; 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It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030054 cell junction;GO:0030424 axon;GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "GO:0002260 lymphocyte homeostasis;GO:0007009 plasma membrane organization;GO:0030036 actin cytoskeleton organization;GO:0030097 hemopoiesis;GO:0008360 regulation of cell shape", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "D4A678-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A7E9-1", "uniprot_id": [ { "id": "D4A7E9_RAT", "url": "https://www.uniprot.org/uniprot/D4A7E9", "type": "external" } ], "mass": 42913.0, "length": 398, "protein_name": "Stomatin-like protein 1", "gene_name": "Stoml1", "organism": "Rat", "refseq_name": "stomatin-like protein 1", "refseq_ac": [ { "id": "NP_001292167", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292167", "type": "external" } ], "gene_names_uniprotkb": "Stoml1", "gene_names_refseq": "RGD1559463; Stoml1", "protein_names_uniprotkb": "Stomatin-like protein 1", "protein_names_refseq": "stomatin (EPB72)-like 1; stomatin-like protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:300748)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008200 ion channel inhibitor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045121 membrane raft;GO:0031410 cytoplasmic vesicle;GO:0031902 late endosome membrane", "go_biological_process": "GO:0006869 lipid transport;GO:1990830 cellular response to leukemia inhibitory factor", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A7E9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A8Z5-1", "uniprot_id": [ { "id": "D4A8Z5_RAT", "url": "https://www.uniprot.org/uniprot/D4A8Z5", "type": "external" } ], "mass": 24319.0, "length": 218, "protein_name": "Protein N-lysine methyltransferase METTL21A", "gene_name": "Mettl21a", "organism": "Rat", "refseq_name": "protein N-lysine methyltransferase METTL21A", "refseq_ac": [ { "id": "NP_001386380", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386380", "type": "external" } ], "gene_names_uniprotkb": "Mettl21a; LOC102553119", "gene_names_refseq": "Fam119a; Mettl21a; RGD1311824", "protein_names_uniprotkb": "Protein N-lysine methyltransferase METTL21A; Methyltransferase-like protein 21A", "protein_names_refseq": "family with sequence similarity 119, member A; methyltransferase like 21A; protein N-lysine methyltransferase METTL21A-like; protein N-lysine methyltransferase METTL21A", "tax_id": 10116, "disease": "", "pathway": " (rno:102553119); (R-RNO-8876725)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Protein-lysine methyltransferase that selectively trimethylates residues in heat shock protein 70 (HSP70) family members. Contributes to the in vivo trimethylation of Lys residues in HSPA1 and HSPA8. In vitro methylates 'Lys-561' in HSPA1, 'Lys-564' in HSPA2, 'Lys-585' in HSPA5, 'Lys-563' in HSPA6 and 'Lys-561' in HSPA8., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" }, { "id": "2.1.1.359", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.359", "type": "external" }, { "id": "2.1.1.372", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.372", "type": "external" } ], "go_molecular_function": "GO:0051117 ATPase binding;GO:0031072 heat shock protein binding;GO:0008276 protein methyltransferase activity;GO:0030544 Hsp70 protein binding;GO:0016279 protein-lysine N-methyltransferase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0032991 protein-containing complex", "go_biological_process": "GO:0006479 protein methylation;GO:1903333 negative regulation of protein folding", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A8Z5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A9M3-1", "uniprot_id": [ { "id": "D4A9M3_RAT", "url": "https://www.uniprot.org/uniprot/D4A9M3", "type": "external" } ], "mass": 36262.0, "length": 320, "protein_name": "Olfactory receptor", "gene_name": "Or2a20", "organism": "Rat", "refseq_name": "olfactory receptor Olr820", "refseq_ac": [ { "id": "NP_001000974", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000974", "type": "external" } ], "gene_names_uniprotkb": "Or2a20", "gene_names_refseq": "Olr820; Or2a20", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 820; olfactory receptor Olr820; olfactory receptor gene Olr820", "tax_id": 10116, "disease": "", "pathway": " (rno:405329)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A9M3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A9Q3-1", "uniprot_id": [ { "id": "D4A9Q3_RAT", "url": "https://www.uniprot.org/uniprot/D4A9Q3", "type": "external" } ], "mass": 15733.0, "length": 143, "protein_name": "Small ribosomal subunit protein uS12", "gene_name": "Rps23l1", "organism": "Rat", "refseq_name": "small ribosomal subunit protein uS12-like", "refseq_ac": [ { "id": "XP_038948515", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038948515", "type": "external" } ], "gene_names_uniprotkb": "Rps23l1; AABR07072400.1; RGD1563570", "gene_names_refseq": "Rps23l1", "protein_names_uniprotkb": "Small ribosomal subunit protein uS12; 40S ribosomal protein S23", "protein_names_refseq": "small ribosomal subunit protein uS12-like", "tax_id": 10116, "disease": "brachycephaly, trichomegaly, and developmental delay (Disease Ontology:DOID:0070415)", "pathway": " (rno:498360)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005791 rough endoplasmic reticulum;GO:0005840 ribosome;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A9Q3-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AAG7-1", "uniprot_id": [ { "id": "D4AAG7_RAT", "url": "https://www.uniprot.org/uniprot/D4AAG7", "type": "external" } ], "mass": 35516.0, "length": 315, "protein_name": "Olfactory receptor", "gene_name": "Or9r3b", "organism": "Rat", "refseq_name": "olfactory receptor Olr1067", "refseq_ac": [ { "id": "NP_001000697", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000697", "type": "external" } ], "gene_names_uniprotkb": "Or9r3b", "gene_names_refseq": "Olr1067; Or9r3b", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1067; olfactory receptor Olr1067; olfactory receptor gene Olr1067", "tax_id": 10116, "disease": "", "pathway": " (rno:404903)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4AAG7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AAR7-1", "uniprot_id": [ { "id": "D4AAR7_RAT", "url": "https://www.uniprot.org/uniprot/D4AAR7", "type": "external" } ], "mass": 143274.0, "length": 1249, "protein_name": "Coiled-coil domain containing 136", "gene_name": "Ccdc136", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ccdc136", "gene_names_refseq": "", "protein_names_uniprotkb": "Coiled-coil domain containing 136", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:362331)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0002080 acrosomal membrane", "go_biological_process": "GO:0007283 spermatogenesis;GO:0007338 single fertilization;GO:0001675 acrosome assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4AAR7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AAT1-1", "uniprot_id": [ { "id": "D4AAT1_RAT", "url": "https://www.uniprot.org/uniprot/D4AAT1", "type": "external" } ], "mass": 99271.0, "length": 905, "protein_name": "ADAM metallopeptidase with thrombospondin type 1 motif, 8", "gene_name": "Adamts8", "organism": "Rat", "refseq_name": "A disintegrin and metalloproteinase with thrombospondin motifs 8 precursor", "refseq_ac": [ { "id": "NP_001414107", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414107", "type": "external" } ], "gene_names_uniprotkb": "Adamts8", "gene_names_refseq": "Adamts8", "protein_names_uniprotkb": "ADAM metallopeptidase with thrombospondin type 1 motif, 8", "protein_names_refseq": "A disintegrin and metalloproteinase with thrombospondin motifs 8 precursor; A disintegrin and metalloproteinase with thrombospondin motifs 8; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8", "tax_id": 10116, "disease": "", "pathway": " (rno:300475); (R-RNO-5173214)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "21257285;37424113", "class_list": "", "function": "After myocardial infarction, ADAMTS8 mRNA increased at 6 h, peaked at 24 h, remained high at 3 d, then decreased gradually., [RefSeq, PubMed]; Expression of placental growth factor and a disintegrin and metalloprotease with a thrombospondin type motifs 1-4-8 during the three trimesters of rat pregnancy at the maternal-fetal interface., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008201 heparin binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0031012 extracellular matrix", "go_biological_process": "GO:0006508 proteolysis;GO:0030198 extracellular matrix organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D4AAT1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AAZ2-1", "uniprot_id": [ { "id": "D4AAZ2_RAT", "url": "https://www.uniprot.org/uniprot/D4AAZ2", "type": "external" } ], "mass": 45508.0, "length": 415, "protein_name": "Zona pellucida-like domain-containing protein 1", "gene_name": "Zpld1", "organism": "Rat", "refseq_name": "zona pellucida-like domain-containing protein 1", "refseq_ac": [ { "id": "XP_038944667", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038944667", "type": "external" } ], "gene_names_uniprotkb": "Zpld1", "gene_names_refseq": "Zpld1", "protein_names_uniprotkb": "Zona pellucida-like domain-containing protein 1; Cupulin", "protein_names_refseq": "zona pellucida-like domain-containing protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:363768)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Glycoprotein which is a component of the gelatinous extracellular matrix in the cupulae of the vestibular organ., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0009986 cell surface;GO:0030659 cytoplasmic vesicle membrane", "go_biological_process": "GO:0060005 vestibular reflex", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4AAZ2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ABN8-1", "uniprot_id": [ { "id": "D4ABN8_RAT", "url": "https://www.uniprot.org/uniprot/D4ABN8", "type": "external" } ], "mass": 194726.0, "length": 1719, "protein_name": "5'-3' exoribonuclease 1", "gene_name": "Xrn1", "organism": "Rat", "refseq_name": "5'-3' exoribonuclease 1", "refseq_ac": [ { "id": "NP_001292169", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292169", "type": "external" } ], "gene_names_uniprotkb": "Xrn1", "gene_names_refseq": "RGD1309713; Xrn1", "protein_names_uniprotkb": "5'-3' exoribonuclease 1; 3.1.13.-", "protein_names_refseq": "5'-3' exoribonuclease 1", "tax_id": 10116, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652)", "pathway": " (rno:300944); (R-RNO-450385); (R-RNO-450513)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "25736288", "class_list": "", "function": "XRN1 knockdown impairs the translational repression triggered by NMDA. Collectively, these observations support a role for the SX-bodies in the reversible masking and silencing of mRNAs at the synapse., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.1.62", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.62", "type": "external" }, { "id": "3.1.13.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.-", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0002151 G-quadruplex RNA binding;GO:0051880 G-quadruplex DNA binding;GO:0004534 5'-3' RNA exonuclease activity;GO:0070034 telomerase RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0030425 dendrite", "go_biological_process": "GO:0071028 nuclear mRNA surveillance;GO:0071409 cellular response to cycloheximide;GO:0017148 negative regulation of translation;GO:0006402 mRNA catabolic process;GO:0000956 nuclear-transcribed mRNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4ABN8-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ABZ5-1", "uniprot_id": [ { "id": "D4ABZ5_RAT", "url": "https://www.uniprot.org/uniprot/D4ABZ5", "type": "external" } ], "mass": 59206.0, "length": 527, "protein_name": "DNA polymerase epsilon subunit", "gene_name": "Pole2", "organism": "Rat", "refseq_name": "DNA polymerase epsilon subunit 2", "refseq_ac": [ { "id": "NP_001162579", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162579", "type": "external" } ], "gene_names_uniprotkb": "Pole2", "gene_names_refseq": "Pole2", "protein_names_uniprotkb": "DNA polymerase epsilon subunit; DNA polymerase II subunit 2", "protein_names_refseq": "DNA polymerase epsilon subunit 2; polymerase (DNA directed), epsilon 2 (p59 subunit); polymerase (DNA directed), epsilon 2, accessory subunit; polymerase (DNA) epsilon 2, accessory subunit", "tax_id": 10116, "disease": "", "pathway": " (rno:299112); (R-RNO-110314); (R-RNO-5651801); (R-RNO-5656169); (R-RNO-5685942); (R-RNO-5693537); (R-RNO-5696397); (R-RNO-5696400); (R-RNO-6782135); (R-RNO-6782210); (R-RNO-68952); (R-RNO-68962)", "pathway_count": 12, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Accessory component of the DNA polymerase epsilon complex. Participates in DNA repair and in chromosomal DNA replication., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0008622 epsilon DNA polymerase complex;GO:0005654 nucleoplasm;GO:0016604 nuclear body", "go_biological_process": "GO:0042276 error-prone translesion synthesis;GO:0006261 DNA-templated DNA replication", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4ABZ5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AC93-1", "uniprot_id": [ { "id": "D4AC93_RAT", "url": "https://www.uniprot.org/uniprot/D4AC93", "type": "external" } ], "mass": 21674.0, "length": 199, "protein_name": "Transmembrane protein 223", "gene_name": "Tmem223", "organism": "Rat", "refseq_name": "transmembrane protein 223", "refseq_ac": [ { "id": "NP_001178033", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178033", "type": "external" } ], "gene_names_uniprotkb": "Tmem223; LOC686289", "gene_names_refseq": "Tmem223", "protein_names_uniprotkb": "Transmembrane protein 223", "protein_names_refseq": "transmembrane protein 223", "tax_id": 10116, "disease": "", "pathway": " (rno:690285)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0097177 mitochondrial ribosome binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0033617 mitochondrial respiratory chain complex IV assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4AC93-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ACB1-1", "uniprot_id": [ { "id": "D4ACB1_RAT", "url": "https://www.uniprot.org/uniprot/D4ACB1", "type": "external" } ], "mass": 35192.0, "length": 316, "protein_name": "Olfactory receptor", "gene_name": "Or9i1b", "organism": "Rat", "refseq_name": "olfactory receptor Olr384", "refseq_ac": [ { "id": "NP_001000263", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000263", "type": "external" } ], "gene_names_uniprotkb": "Or9i1b", "gene_names_refseq": "Olr384; Or9i1b", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 384; olfactory receptor Olr384; olfactory receptor gene Olr384", "tax_id": 10116, "disease": "", "pathway": " (rno:293817)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4ACB1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ACU7-1", "uniprot_id": [ { "id": "D4ACU7_RAT", "url": "https://www.uniprot.org/uniprot/D4ACU7", "type": "external" } ], "mass": 36560.0, "length": 322, "protein_name": "Olfactory receptor", "gene_name": "Or12d13", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Or12d13; Olr1734", "gene_names_refseq": "", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 1, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4ACU7-1", "record_type": "protein", "filter_code": "0000000.1000000.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AD70-1", "uniprot_id": [ { "id": "D4AD70_RAT", "url": "https://www.uniprot.org/uniprot/D4AD70", "type": "external" } ], "mass": 8246.0, "length": 70, "protein_name": "Large ribosomal subunit protein eL38", "gene_name": "Rpl38l1", "organism": "Rat", "refseq_name": "large ribosomal subunit protein eL38-like", "refseq_ac": [ { "id": "XP_038964549", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038964549", "type": "external" } ], "gene_names_uniprotkb": "Rpl38l1; AABR07060145.1; RGD1561636", "gene_names_refseq": "Rpl38l1", "protein_names_uniprotkb": "Large ribosomal subunit protein eL38; 60S ribosomal protein L38", "protein_names_refseq": "large ribosomal subunit protein eL38-like", "tax_id": 10116, "disease": "otitis media (Disease Ontology:DOID:10754)", "pathway": " (rno:502741)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0006412 translation;GO:0022618 protein-RNA complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4AD70-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AEA3-1", "uniprot_id": [ { "id": "D4AEA3_RAT", "url": "https://www.uniprot.org/uniprot/D4AEA3", "type": "external" } ], "mass": 54064.0, "length": 491, "protein_name": "Peptidoglycan recognition protein 4", "gene_name": "Pglyrp4", "organism": "Rat", "refseq_name": "peptidoglycan recognition protein 4 isoform X1", "refseq_ac": [ { "id": "XP_063137890", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063137890", "type": "external" } ], "gene_names_uniprotkb": "Pglyrp4", "gene_names_refseq": "Pglyrp4", "protein_names_uniprotkb": "Peptidoglycan recognition protein 4", "protein_names_refseq": "peptidoglycan recognition protein 4 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-6803157)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Also binds to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. 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The 17S U2 SnRNP complex (1) directly participates in early spliceosome assembly and (2) mediates recognition of the intron branch site during pre-mRNA splicing by promoting the selection of the pre-mRNA branch-site adenosine, the nucleophile for the first step of splicing. Within the 17S U2 SnRNP complex, SF3B3 is part of the SF3B subcomplex, which is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence in pre-mRNA. Sequence independent binding of SF3A and SF3B subcomplexes upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Also acts as a component of the minor spliceosome, which is involved in the splicing of U12-type introns in pre-mRNAs., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030620 U2 snRNA binding;GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005681 spliceosomal complex;GO:0071013 catalytic step 2 spliceosome", "go_biological_process": "GO:0042177 negative regulation of protein catabolic process;GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E9PT66-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E9PTU9-1", "uniprot_id": [ { "id": "E9PTU9_RAT", "url": "https://www.uniprot.org/uniprot/E9PTU9", "type": "external" } ], "mass": 44971.0, "length": 391, "protein_name": "Bone morphogenetic protein 15", "gene_name": "Bmp15", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Bmp15", "gene_names_refseq": "", "protein_names_uniprotkb": "Bone morphogenetic protein 15", "protein_names_refseq": "", "tax_id": 10116, "disease": "ovarian dysgenesis 2 (Disease Ontology:DOID:0080494); 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LOC102553503; LOC120101034; LOC120101038; LOC134485799; RGD1559714; RGD1563667; Spopfm2l1; Tdpoz2l8", "gene_names_refseq": "RGD1563667; Spopfm2l2; Tdpoz-T2", "protein_names_uniprotkb": "Speckle-type BTB/POZ protein family member 2 like 1", "protein_names_refseq": "RAF domain and POZ/BTB containing protein T2", "tax_id": 10116, "disease": "", "pathway": " (rno:365855); (rno:502570)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8I6GB22", "ec_number_list": [], "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0030162 regulation of proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E9PTZ3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E9PU08-1", "uniprot_id": [ { "id": "E9PU08_RAT", "url": "https://www.uniprot.org/uniprot/E9PU08", "type": "external" } ], "mass": 71023.0, "length": 630, "protein_name": "Solute carrier family 22, member 14", "gene_name": "Slc22a14", "organism": "Rat", "refseq_name": "solute carrier family 22 member 14 isoform 1", "refseq_ac": [ { "id": "NP_001101663", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101663", "type": "external" } ], "gene_names_uniprotkb": "Slc22a14; AABR07071731.1", "gene_names_refseq": "Slc22a14", "protein_names_uniprotkb": "Solute carrier family 22, member 14", "protein_names_refseq": "solute carrier family 22 (organic cation transporter), member 14; solute carrier family 22 member 14 isoform 1", "tax_id": 10116, "disease": "", "pathway": " (rno:316061)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0032217 riboflavin transmembrane transporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0097228 sperm principal piece", "go_biological_process": "GO:0030317 flagellated sperm motility;GO:0048240 sperm capacitation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E9PU08-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LNK6-1", "uniprot_id": [ { "id": "F1LNK6_RAT", "url": "https://www.uniprot.org/uniprot/F1LNK6", "type": "external" } ], "mass": 49336.0, "length": 417, "protein_name": "DNA primase", "gene_name": "Prim1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Prim1; LOC134479640", "gene_names_refseq": "", "protein_names_uniprotkb": "DNA primase; 2.7.7.-", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-113501); (R-RNO-174411); (R-RNO-174430); (R-RNO-68952); (R-RNO-68962); (R-RNO-69091); (R-RNO-69166); (R-RNO-69183)", "pathway_count": 8, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.7.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.-", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0003899 DNA-directed RNA polymerase activity;GO:0000287 magnesium ion binding;GO:0008270 zinc ion binding;GO:0032553 ribonucleotide binding", "go_cellular_component": "GO:0005658 alpha DNA polymerase:primase complex", "go_biological_process": "GO:0006269 DNA replication, synthesis of primer;GO:0006270 DNA replication initiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LNK6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LTD0-1", "uniprot_id": [ { "id": "F1LTD0_RAT", "url": "https://www.uniprot.org/uniprot/F1LTD0", "type": "external" } ], "mass": 52783.0, "length": 455, "protein_name": "G protein-coupled receptor 89B", "gene_name": "Gpr89", "organism": "Rat", "refseq_name": "G protein-coupled receptor 89", "refseq_ac": [ { "id": "NP_001132958", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001132958", "type": "external" } ], "gene_names_uniprotkb": "Gpr89; Gpr89b", "gene_names_refseq": "Gphra; Gphr; Gpr89b; Gpr89; RGD1304837", "protein_names_uniprotkb": "G protein-coupled receptor 89B", "protein_names_refseq": "G protein-coupled receptor 89B; G protein-coupled receptor 89", "tax_id": 10116, "disease": "", "pathway": " (rno:362003)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.8.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.-.-", "type": "external" }, { "id": "1.8.5.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.5.1", "type": "external" } ], "go_molecular_function": "GO:0008308 voltage-gated monoatomic anion channel activity", "go_cellular_component": "GO:0032580 Golgi cisterna membrane;GO:0030660 Golgi-associated vesicle membrane;GO:0016020 membrane", "go_biological_process": "GO:0030217 T cell differentiation;GO:0051452 intracellular pH reduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LTD0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LTR3-1", "uniprot_id": [ { "id": "F1LTR3_RAT", "url": "https://www.uniprot.org/uniprot/F1LTR3", "type": "external" } ], "mass": 148129.0, "length": 1308, "protein_name": "Putative ATP-dependent RNA helicase TDRD12", "gene_name": "Tdrd12", "organism": "Rat", "refseq_name": "tudor domain containing 12 isoform 1", "refseq_ac": [ { "id": "NP_001419536", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001419536", "type": "external" } ], "gene_names_uniprotkb": "Tdrd12", "gene_names_refseq": "RGD1562792; Tdrd12", "protein_names_uniprotkb": "Putative ATP-dependent RNA helicase TDRD12; 3.6.4.13; ES cell-associated transcript 8 protein; Tudor domain-containing protein 12", "protein_names_refseq": "putative ATP-dependent RNA helicase TDRD12; tudor domain containing 12 isoform 1", "tax_id": 10116, "disease": "", "pathway": " (rno:689639)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Probable ATP-binding RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process. Acts via the PET complex, a multiprotein complex required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "7.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.9.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.9.1.1", "type": "external" }, { "id": "6.1.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.12", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003676 nucleic acid binding;GO:0003724 RNA helicase activity", "go_cellular_component": "GO:1990923 PET complex", "go_biological_process": "GO:0007283 spermatogenesis;GO:0009566 fertilization;GO:0007140 male meiotic nuclear division;GO:0034587 piRNA processing;GO:0042078 germ-line stem cell division", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LTR3-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LUG6-1", "uniprot_id": [ { "id": "F1LUG6_RAT", "url": "https://www.uniprot.org/uniprot/F1LUG6", "type": "external" } ], "mass": 36289.0, "length": 330, "protein_name": "Tetratricopeptide repeat domain 24", "gene_name": "Ttc24", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ttc24", "gene_names_refseq": "", "protein_names_uniprotkb": "Tetratricopeptide repeat domain 24", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:100361582)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LUG6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LVN2-1", "uniprot_id": [ { "id": "F1LVN2_RAT", "url": "https://www.uniprot.org/uniprot/F1LVN2", "type": "external" } ], "mass": 35579.0, "length": 314, "protein_name": "Olfactory receptor", "gene_name": "Olr1481", "organism": "Rat", "refseq_name": "olfactory receptor Olr1482", "refseq_ac": [ { "id": "NP_001000026", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000026", "type": "external" } ], "gene_names_uniprotkb": "Olr1481; Or1e16", "gene_names_refseq": "Olr1482; Or1e16", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1482; olfactory receptor Olr1482; olfactory receptor gene Olr1482", "tax_id": 10116, "disease": "", "pathway": " (rno:287484); (rno:363639)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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Also stimulates B-cells. Binds to and activates the ILST/gp130 receptor., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0005125 cytokine activity;GO:0005127 ciliary neurotrophic factor receptor binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0097058 CRLF-CLCF1 complex;GO:0097059 CNTFR-CLCF1 complex", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0008284 positive regulation of cell population proliferation;GO:0043524 negative regulation of neuron apoptotic process;GO:0030890 positive regulation of B cell proliferation;GO:0030183 B cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F7EKG3-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "G3V7J5-1", "uniprot_id": [ { "id": "EST2E_RAT", "url": "https://www.uniprot.org/uniprot/G3V7J5", "type": "external" } ], "mass": 63583.0, "length": 567, "protein_name": "Pyrethroid hydrolase Ces2e", "gene_name": "Ces2e", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ces2e", "gene_names_refseq": "", "protein_names_uniprotkb": "Pyrethroid hydrolase Ces2e; 3.1.1.-; 3.1.1.88; Carboxylic ester hydrolase", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "12230550", "class_list": "", "function": "Carboxylesterase that catalyzes the hydrolysis of pyrethroids pesticides. Hydrolyzes trans-permethrin at a rate about 22-fold higher than cis-permethrin. Also hydrolyzes trans-cypermethrin (By similarity). Hydrolyzes retinyl esters (PubMed:12230550)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O35535", "ec_number_list": [ { "id": "3.1.1.88", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.88", "type": "external" }, { "id": "3.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.-", "type": "external" }, { "id": "3.1.1.28", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.28", "type": "external" }, { "id": "3.1.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.23", "type": "external" }, { "id": "3.1.1.79", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.79", "type": "external" }, { "id": "3.1.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.1", "type": "external" }, { "id": "3.1.1.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.67", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" } ], "go_molecular_function": "GO:0102209 trans-permethrin hydrolase activity;GO:0050253 retinyl-palmitate esterase activity;GO:0047376 all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity;GO:0106435 carboxylesterase activity", "go_cellular_component": "GO:0043231 intracellular membrane-bounded organelle", "go_biological_process": "GO:0001523 retinoid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "G3V7J5-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R3Z9-1", "uniprot_id": [ { "id": "M0R3Z9_RAT", "url": "https://www.uniprot.org/uniprot/M0R3Z9", "type": "external" } ], "mass": 22270.0, "length": 213, "protein_name": "Keratin-associated protein", "gene_name": "Krtap26-1", "organism": "Rat", "refseq_name": "keratin-associated protein 26-1", "refseq_ac": [ { "id": "XP_003751060", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003751060", "type": "external" } ], "gene_names_uniprotkb": "Krtap26-1; LOC684589", "gene_names_refseq": "Krtap26-1", "protein_names_uniprotkb": "Keratin-associated protein", "protein_names_refseq": "keratin-associated protein 26-1", "tax_id": 10116, "disease": "", "pathway": " (rno:684589)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0005829 cytosol;GO:0045095 keratin filament", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R3Z9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R487-1", "uniprot_id": [ { "id": "M0R487_RAT", "url": "https://www.uniprot.org/uniprot/M0R487", "type": "external" } ], "mass": 30353.0, "length": 264, "protein_name": "Y-linked testis-specific protein 1-like", "gene_name": "LOC103694726", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LOC103694726; LOC134478838; LOC134484320; LOC134484371; LOC134484471", "gene_names_refseq": "", "protein_names_uniprotkb": "Y-linked testis-specific protein 1-like", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0007276 gamete generation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R487-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R494-1", "uniprot_id": [ { "id": "M0R494_RAT", "url": "https://www.uniprot.org/uniprot/M0R494", "type": "external" } ], "mass": 60318.0, "length": 529, "protein_name": "Zinc finger protein 420", "gene_name": "Zfp420", "organism": "Rat", "refseq_name": "zinc finger protein 383 isoform X1", "refseq_ac": [ { "id": "XP_038949669", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038949669", "type": "external" } ], "gene_names_uniprotkb": "Zfp420", "gene_names_refseq": "Zfp420", "protein_names_uniprotkb": "Zinc finger protein 420", "protein_names_refseq": "zinc finger protein 383 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:103690163)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0001835 blastocyst hatching", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R494-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R499-1", "uniprot_id": [ { "id": "M0R499_RAT", "url": "https://www.uniprot.org/uniprot/M0R499", "type": "external" } ], "mass": 35646.0, "length": 315, "protein_name": "Olfactory receptor", "gene_name": "Or2t47", "organism": "Rat", "refseq_name": "olfactory receptor Olr1425", "refseq_ac": [ { "id": "NP_001000010", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000010", "type": "external" } ], "gene_names_uniprotkb": "Or2t47", "gene_names_refseq": "Olr1425; Or2t47", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1425; olfactory receptor Olr1425; olfactory receptor gene Olr1425", "tax_id": 10116, "disease": "", "pathway": " (rno:287316)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R499-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R5Y9-1", "uniprot_id": [ { "id": "M0R5Y9_RAT", "url": "https://www.uniprot.org/uniprot/M0R5Y9", "type": "external" } ], "mass": 19591.0, "length": 167, "protein_name": "tRNA-splicing ligase-activating factor archease", "gene_name": "Zbtb8os", "organism": "Rat", "refseq_name": "protein archease isoform 1", "refseq_ac": [ { "id": "NP_001386418", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386418", "type": "external" } ], "gene_names_uniprotkb": "Zbtb8os", "gene_names_refseq": "RGD1562249; 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Involved in BMP signaling and in the regulation of the immature compartment of the hematopoietic system. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved specification of B-cell lineage; this interaction preventing EBF1 to bind DNA and activate target genes., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0019904 protein domain specific binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JT53-1", "record_type": "protein", "filter_code": "0000000.0000110.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JTM9-1", "uniprot_id": [ { "id": "A0A0G2JTM9_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JTM9", "type": "external" } ], "mass": 42142.0, "length": 377, "protein_name": "DnaJ homolog subfamily B member 14", "gene_name": "Dnajb14", "organism": "Rat", "refseq_name": "dnaJ homolog subfamily B member 14", "refseq_ac": [ { "id": "NP_001102663", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102663", "type": "external" } ], "gene_names_uniprotkb": "Dnajb14", "gene_names_refseq": "Dnajb14", "protein_names_uniprotkb": "DnaJ homolog subfamily B member 14", "protein_names_refseq": "DnaJ (Hsp40) homolog, subfamily B, member 14; 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congestive heart failure (Disease Ontology:DOID:6000)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007507 heart development;GO:0033574 response to testosterone", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JXI7-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JXQ3-1", "uniprot_id": [ { "id": "A0A0G2JXQ3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JXQ3", "type": "external" } ], "mass": 35974.0, "length": 324, "protein_name": "Olfactory receptor", "gene_name": "Or6all1", "organism": "Rat", "refseq_name": "olfactory receptor 6E1-like", "refseq_ac": [ { "id": "XP_008757096", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008757096", "type": "external" } ], "gene_names_uniprotkb": "Or6all1; LOC103689958", "gene_names_refseq": "LOC103689958", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 6E1-like", "tax_id": 10116, "disease": "", "pathway": " (rno:103689958)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JXQ3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JXV9-1", "uniprot_id": [ { "id": "A0A0G2JXV9_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JXV9", "type": "external" } ], "mass": 26503.0, "length": 248, "protein_name": "Paired related homeobox 2", "gene_name": "Prrx2", "organism": "Rat", "refseq_name": "paired mesoderm homeobox protein 2", "refseq_ac": [ { "id": "NP_001402085", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001402085", "type": "external" } ], "gene_names_uniprotkb": "Prrx2", "gene_names_refseq": "Prrx2; Prx2", "protein_names_uniprotkb": "Paired related homeobox 2", "protein_names_refseq": "paired mesoderm homeobox protein 2", "tax_id": 10116, "disease": "", "pathway": " (rno:113931)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "22577874;23644741;24881871;25795141;39434056", "class_list": "", "function": "Data indicate that PRXs are produced in the pituitary progenitor cells and may play roles in the process of terminal differentiation during early pituitary organogenesis., [RefSeq, PubMed]; Expression stimulated by Klf6, [RefSeq, PubMed]; PRRX1- and PRRX2-positive mesenchymal stem/progenitor cells are present at the periphery of the embryonic pituitary and participate in pituitary vasculogenesis by differentiation into vascular endothelial cells and pericytes., [RefSeq, PubMed]; PRX proteins, especially PRX2, play a role in the morphogenesis of the primordial tissues formed by the epithelio-mesenchymal interaction and that neural crest cells contribute to the morphogenesis of tissues derived from the cranial placode., [RefSeq, PubMed]; Upregulation of PRRX2 by silencing Marveld3 as a protective mechanism against radiation-induced ferroptosis in skin cells. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0045880 positive regulation of smoothened signaling pathway;GO:0006357 regulation of transcription by RNA polymerase II;GO:0042472 inner ear morphogenesis;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0030326 embryonic limb morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0G2JXV9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JZ53-1", "uniprot_id": [ { "id": "A0A0G2JZ53_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JZ53", "type": "external" } ], "mass": 539426.0, "length": 4949, "protein_name": "Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6", "gene_name": "Birc6", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Birc6", "gene_names_refseq": "", "protein_names_uniprotkb": "Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6; 2.3.2.24; BIR repeat-containing ubiquitin-conjugating enzyme; Baculoviral IAP repeat-containing protein 6; Ubiquitin-conjugating BIR domain enzyme apollon", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004842 ubiquitin-protein transferase activity;GO:0004869 cysteine-type endopeptidase inhibitor activity;GO:0061631 ubiquitin conjugating enzyme activity", "go_cellular_component": "GO:0000922 spindle pole;GO:0005634 nucleus;GO:0005768 endosome;GO:0005794 Golgi apparatus;GO:0005813 centrosome", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0042127 regulation of cell population proliferation;GO:0043066 negative regulation of apoptotic process;GO:0051301 cell division;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JZ53-1", "record_type": "protein", "filter_code": "0000000.0000100.000100.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R7R1-1", "uniprot_id": [ { "id": "M0R7R1_RAT", "url": "https://www.uniprot.org/uniprot/M0R7R1", "type": "external" } ], "mass": 62354.0, "length": 561, "protein_name": "Carboxylic ester hydrolase", "gene_name": "Cesl1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Cesl1", "gene_names_refseq": "", "protein_names_uniprotkb": "Carboxylic ester hydrolase; 3.1.1.-", "protein_names_refseq": "", "tax_id": 10116, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); stomach cancer (Disease Ontology:DOID:10534); gastrointestinal system cancer (Disease Ontology:DOID:3119); hepatocellular carcinoma (Disease Ontology:DOID:684); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (rno:501232)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0052689 carboxylic ester hydrolase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R7R1-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JUN6-1", "uniprot_id": [ { "id": "A0A0G2JUN6_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JUN6", "type": "external" } ], "mass": 209779.0, "length": 1863, "protein_name": "Fer-1-like protein 6", "gene_name": "Fer1l6", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Fer1l6", "gene_names_refseq": "", "protein_names_uniprotkb": "Fer-1-like protein 6", "protein_names_refseq": "", "tax_id": 10116, "disease": "limb-girdle muscular dystrophy (Disease Ontology:DOID:11724)", "pathway": " (rno:314997)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Calcium/phospholipid-binding protein which is essential for proper development of skeletal and cardiac muscle., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0005544 calcium-dependent phospholipid binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0048471 perinuclear region of cytoplasm;GO:0055037 recycling endosome;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0009617 response to bacterium", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JUN6-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K873-1", "uniprot_id": [ { "id": "A0A0G2K873_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K873", "type": "external" } ], "mass": 74116.0, "length": 652, "protein_name": "Asteroid homolog 1", "gene_name": "Aste1", "organism": "Rat", "refseq_name": "protein asteroid homolog 1 isoform X1", "refseq_ac": [ { "id": "XP_063121879", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063121879", "type": "external" } ], "gene_names_uniprotkb": "Aste1", "gene_names_refseq": "Aste1; RGD1304643", "protein_names_uniprotkb": "Asteroid homolog 1", "protein_names_refseq": "protein asteroid homolog 1 isoform X1", "tax_id": 10116, "disease": "mismatch repair cancer syndrome (Disease Ontology:DOID:0112182); Lynch syndrome (Disease Ontology:DOID:3883)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000014 single-stranded DNA endodeoxyribonuclease activity;GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity", "go_cellular_component": "", "go_biological_process": "GO:0006303 double-strand break repair via nonhomologous end joining;GO:0000724 double-strand break repair via homologous recombination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K873-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KAC0-1", "uniprot_id": [ { "id": "A0A0G2KAC0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KAC0", "type": "external" } ], "mass": 40599.0, "length": 370, "protein_name": "Phosphoserine aminotransferase", "gene_name": "Psat1", "organism": "Rat", "refseq_name": "phosphoserine aminotransferase isoform X1", "refseq_ac": [ { "id": "XP_063143070", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063143070", "type": "external" } ], "gene_names_uniprotkb": "Psat1", "gene_names_refseq": "Psa1; Psat1", "protein_names_uniprotkb": "Phosphoserine aminotransferase; 2.6.1.52", "protein_names_refseq": "phosphoserine aminotransferase isoform X1", "tax_id": 10116, "disease": "PSAT deficiency (Disease Ontology:DOID:0050723); Neu-Laxova syndrome 2 (Disease Ontology:DOID:0080075)", "pathway": " (R-RNO-977347)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "18683930", "class_list": "", "function": "Involved in L-serine biosynthesis via the phosphorylated pathway, a three-step pathway converting the glycolytic intermediate 3-phospho-D-glycerate into L-serine. Catalyzes the second step, that is the pyridoxal 5'-phosphate-dependent transamination of 3-phosphohydroxypyruvate and L-glutamate to O-phosphoserine (OPS) and alpha-ketoglutarate. Acts as an inhibitor of ferroptosis in response to interferon-gamma (IFNG) by promoting GPX4 stability: following phosphorylation by CAMK2A, PSAT1 interacts with GPX4 and provides 2-oxoglutarate to EGLN3, leading to GPX4 hydroxylation and stability., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.6.1.52", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.52", "type": "external" } ], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0004648 O-phospho-L-serine:2-oxoglutarate aminotransferase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006564 L-serine biosynthetic process;GO:0110076 negative regulation of ferroptosis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2KAC0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JVD2-1", "uniprot_id": [ { "id": "A0A0G2JVD2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JVD2", "type": "external" } ], "mass": 52483.0, "length": 467, "protein_name": "Mitochondrial adenyl nucleotide antiporter SLC25A23", "gene_name": "Slc25a23", "organism": "Rat", "refseq_name": "mitochondrial adenyl nucleotide antiporter SLC25A23", "refseq_ac": [ { "id": "NP_001100343", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100343", "type": "external" } ], "gene_names_uniprotkb": "Slc25a23", "gene_names_refseq": "Slc25a23", "protein_names_uniprotkb": "Mitochondrial adenyl nucleotide antiporter SLC25A23; Short calcium-binding mitochondrial carrier protein 3; Solute carrier family 25 member 23", "protein_names_refseq": "calcium-binding mitochondrial carrier protein SCaMC-3; mitochondrial adenyl nucleotide antiporter SLC25A23; phosphate carrier), member 23; solute carrier family 25 (mitochondrial carrier", "tax_id": 10116, "disease": "", "pathway": " (rno:301113)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Electroneutral antiporter that mediates the transport of adenine nucleotides through the inner mitochondrial membrane. Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it also acts as a broad specificity adenyl nucleotide antiporter. By regulating the mitochondrial matrix adenine nucleotide pool could adapt to changing cellular energetic demands and indirectly regulate adenine nucleotide-dependent metabolic pathways. Also acts as a regulator of mitochondrial calcium uptake and can probably transport trace amounts of other divalent metal cations in complex with ATP. In vitro, a low activity is also observed with guanyl and pyrimidine nucleotides., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0000295 adenine nucleotide transmembrane transporter activity;GO:0005347 ATP transmembrane transporter activity;GO:0140987 ATP:phosphate antiporter activity;GO:0140988 ADP:phosphate antiporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0043457 regulation of cellular respiration;GO:0071277 cellular response to calcium ion;GO:0006851 mitochondrial calcium ion transmembrane transport;GO:0015866 ADP transport;GO:0036444 calcium import into the mitochondrion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JVD2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JXM5-1", "uniprot_id": [ { "id": "A0A0G2JXM5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JXM5", "type": "external" } ], "mass": 46322.0, "length": 420, "protein_name": "Polymerase delta-interacting protein 3", "gene_name": "Poldip3", "organism": "Rat", "refseq_name": "polymerase delta-interacting protein 3", "refseq_ac": [ { "id": "NP_001123978", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001123978", "type": "external" } ], "gene_names_uniprotkb": "Poldip3", "gene_names_refseq": "Poldip3", "protein_names_uniprotkb": "Polymerase delta-interacting protein 3; S6K1 Aly/REF-like target", "protein_names_refseq": "polymerase (DNA) delta interacting protein 3; polymerase (DNA-directed), delta interacting protein 3; polymerase delta-interacting protein 3", "tax_id": 10116, "disease": "", "pathway": " (rno:315170); (R-RNO-159236)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. Recruits activated ribosomal protein S6 kinase beta-1 I/RPS6KB1 to newly synthesized mRNA. Involved in nuclear mRNA export; probably mediated by association with the TREX complex., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0044877 protein-containing complex binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck;GO:0036464 cytoplasmic ribonucleoprotein granule;GO:0005737 cytoplasm", "go_biological_process": "GO:0016973 poly(A)+ mRNA export from nucleus;GO:0045727 positive regulation of translation;GO:0006417 regulation of translation;GO:0051028 mRNA transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JXM5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K765-1", "uniprot_id": [ { "id": "A0A0G2K765_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K765", "type": "external" } ], "mass": 9246.0, "length": 81, "protein_name": "Uncharacterized protein", "gene_name": "Zfp606", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Zfp606", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, 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BRCA2-associated factor 35; HMG box-containing protein 20B; Structural DNA-binding protein BRAF35", "protein_names_refseq": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related isoform X4", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-3214815); (R-RNO-983231)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0045666 positive regulation of neuron differentiation;GO:0010468 regulation of gene expression;GO:0035914 skeletal muscle cell differentiation;GO:0033234 negative regulation of protein sumoylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A586-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A6E6-1", "uniprot_id": [ { "id": "D4A6E6_RAT", "url": "https://www.uniprot.org/uniprot/D4A6E6", "type": "external" } ], "mass": 48278.0, "length": 411, "protein_name": "Heparan-sulfate 6-O-sulfotransferase", "gene_name": "Hs6st1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Hs6st1", "gene_names_refseq": "", "protein_names_uniprotkb": "Heparan-sulfate 6-O-sulfotransferase; 2.8.2.-", "protein_names_refseq": "", "tax_id": 10116, "disease": "hypogonadotropic hypogonadism 15 with or without anosmia (Disease Ontology:DOID:0090075)", "pathway": " (R-RNO-2022928)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.8.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.2.-", "type": "external" } ], "go_molecular_function": "GO:0008146 sulfotransferase activity;GO:0017095 heparan sulfate 6-sulfotransferase activity", "go_cellular_component": "GO:0016020 membrane;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0001525 angiogenesis;GO:0048286 lung alveolus development;GO:0048666 neuron development;GO:0060716 labyrinthine layer blood vessel development;GO:0015012 heparan sulfate proteoglycan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A6E6-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E9PST5-1", "uniprot_id": [ { "id": "E9PST5_RAT", "url": "https://www.uniprot.org/uniprot/E9PST5", "type": "external" } ], "mass": 151038.0, "length": 1339, "protein_name": "Apoptotic chromatin condensation inducer in the nucleus", "gene_name": "Acin1", "organism": "Rat", "refseq_name": "apoptotic chromatin condensation inducer in the nucleus", "refseq_ac": [ { "id": "NP_001163939", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163939", "type": "external" } ], "gene_names_uniprotkb": "Acin1", "gene_names_refseq": "Acin1", "protein_names_uniprotkb": "Apoptotic chromatin condensation inducer in the nucleus", "protein_names_refseq": "acinus; apoptotic chromatin condensation inducer in the nucleus", "tax_id": 10116, "disease": "", "pathway": " (rno:305884); (R-RNO-111465); (R-RNO-72163)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "16641100;16767516;22673903", "class_list": "", "function": "Data indicate increases in the nuclear levels of caspase-activated acinus and DNase and Endonuclease G (a caspase-independent endonuclease) in CA1 and CA3 pyramidal cell nuclei with different temporal patterns following an AMPA-insult., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003676 nucleic acid binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0016607 nuclear speck;GO:0061574 ASAP complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0043065 positive regulation of apoptotic process;GO:0030218 erythrocyte differentiation;GO:0045657 positive regulation of monocyte differentiation;GO:0008380 RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "E9PST5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A7Z5-1", "uniprot_id": [ { "id": "D4A7Z5_RAT", "url": "https://www.uniprot.org/uniprot/D4A7Z5", "type": "external" } ], "mass": 28772.0, "length": 253, "protein_name": "Diablo IAP-binding mitochondrial protein", "gene_name": "Diablol1; Diablo", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Diablol1; Diablo; Diablo; LOC100360940", "gene_names_refseq": "", "protein_names_uniprotkb": "Diablo IAP-binding mitochondrial protein; Diablo homolog, mitochondrial; Direct IAP-binding protein with low pI", "protein_names_refseq": "", "tax_id": 10116, "disease": "autosomal dominant nonsyndromic deafness 64 (Disease Ontology:DOID:0110585); lung non-small cell carcinoma (Disease Ontology:DOID:3908)", "pathway": " (rno:100360940); (R-RNO-111457); (R-RNO-111463); (R-RNO-111464); (R-RNO-111469); (R-RNO-9627069)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP). Inhibits the activity of BIRC6/BRUCE by inhibiting its binding to caspases., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0009898 cytoplasmic side of plasma membrane;GO:0035631 CD40 receptor complex", "go_biological_process": "GO:0006915 apoptotic process;GO:0051402 neuron apoptotic process;GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0043065 positive regulation of apoptotic process;GO:0097190 apoptotic signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A7Z5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZCK4-1", "uniprot_id": [ { "id": "D3ZCK4_RAT", "url": "https://www.uniprot.org/uniprot/D3ZCK4", "type": "external" } ], "mass": 79398.0, "length": 687, "protein_name": "IRF4-binding protein", "gene_name": "Def6", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Def6", "gene_names_refseq": "", "protein_names_uniprotkb": "IRF4-binding protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "immunodeficiency 87 (Disease Ontology:DOID:0061057); systemic lupus erythematosus (Disease Ontology:DOID:9074)", "pathway": " (rno:309642); (R-RNO-8980692); (R-RNO-9013148); (R-RNO-9013149); (R-RNO-9013404)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005911 cell-cell junction", "go_biological_process": "GO:0098876 vesicle-mediated transport to the plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZCK4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZKH4-1", "uniprot_id": [ { "id": "D3ZKH4_RAT", "url": "https://www.uniprot.org/uniprot/D3ZKH4", "type": "external" } ], "mass": 331559.0, "length": 2958, "protein_name": "Histone-lysine N-methyltransferase ASH1L", "gene_name": "Ash1l", "organism": "Rat", "refseq_name": "histone-lysine N-methyltransferase ASH1L isoform X2", "refseq_ac": [ { "id": "XP_008759376", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008759376", "type": "external" } ], "gene_names_uniprotkb": "Ash1l", "gene_names_refseq": "Ash1l", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase ASH1L; 2.1.1.359; 2.1.1.367; ASH1-like protein; Absent small and homeotic disks protein 1 homolog", "protein_names_refseq": "histone-lysine N-methyltransferase ASH1L isoform X2", "tax_id": 10116, "disease": "developmental disorder of mental health (Disease Ontology:DOID:0060037); autism spectrum disorder (Disease Ontology:DOID:0060041); autosomal dominant intellectual developmental disorder 52 (Disease Ontology:DOID:0080231); leukemia (Disease Ontology:DOID:1240)", "pathway": " (rno:310638); (R-RNO-3214841)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Histone methyltransferase specifically trimethylating 'Lys-36' of histone H3 forming H3K36me3. Also monomethylates 'Lys-9' of histone H3 (H3K9me1) in vitro. The physiological significance of the H3K9me1 activity is unclear., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.367", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.367", "type": "external" }, { "id": "2.1.1.357", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.357", "type": "external" }, { "id": "2.1.1.359", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.359", "type": "external" }, { "id": "2.1.1.372", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.372", "type": "external" }, { "id": "2.1.1.366", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.366", "type": "external" }, { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" }, { "id": "2.1.1.355", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.355", "type": "external" }, { "id": "2.1.1.354", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.354", "type": "external" }, { "id": "2.1.1.362", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.362", "type": "external" }, { "id": "2.1.1.361", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.361", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0042800 histone H3K4 methyltransferase activity;GO:0046975 histone H3K36 methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005923 bicellular tight junction;GO:0016604 nuclear body;GO:0005694 chromosome", "go_biological_process": "GO:0048733 sebaceous gland development;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0002674 negative regulation of acute inflammatory response;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZKH4-1", "record_type": "protein", "filter_code": "0000000.0000011.001000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZC55-1", "uniprot_id": [ { "id": "D3ZC55_RAT", "url": "https://www.uniprot.org/uniprot/D3ZC55", "type": "external" } ], "mass": 74830.0, "length": 675, "protein_name": "Heat shock 70 kDa protein 12A", "gene_name": "Hspa12a", "organism": "Rat", "refseq_name": "heat shock 70 kDa protein 12A isoform 2", "refseq_ac": [ { "id": "NP_001100915", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100915", "type": "external" } ], "gene_names_uniprotkb": "Hspa12a", "gene_names_refseq": "Hspa12a", "protein_names_uniprotkb": "Heat shock 70 kDa protein 12A", "protein_names_refseq": "heat shock 70 kDa protein 12A isoform 2; heat shock 70kDa protein 12A; heat shock protein 12A", "tax_id": 10116, "disease": "", "pathway": " (rno:307997); (R-RNO-3371453)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "16641100;22673903;38843836", "class_list": "", "function": "Adapter protein for SORL1, but not SORT1. 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bcl-2-like protein 12", "tax_id": 10116, "disease": "", "pathway": " (rno:361567)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "22673903;29393594", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0002039 p53 binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006915 apoptotic process;GO:0043066 negative regulation of apoptotic process;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:2000773 negative regulation of cellular senescence;GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3Z9I2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A748-1", "uniprot_id": [ { "id": "D4A748_RAT", "url": "https://www.uniprot.org/uniprot/D4A748", "type": "external" } ], "mass": 355154.0, "length": 3187, "protein_name": "WDFY family member 4", "gene_name": "Wdfy4", "organism": "Rat", "refseq_name": "WD repeat- and FYVE domain-containing protein 4", "refseq_ac": [ { "id": "NP_001414587", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414587", "type": "external" } ], "gene_names_uniprotkb": "Wdfy4; 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Ccdc58", "gene_names_refseq": "Ccdc58; Mix23; RGD1564582", "protein_names_uniprotkb": "Protein MIX23; Coiled-coil domain-containing protein 58", "protein_names_refseq": "coiled-coil domain containing 58; coiled-coil domain-containing protein 58; protein MIX23", "tax_id": 10116, "disease": "", "pathway": " (rno:288065)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16641100", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005758 mitochondrial intermembrane space;GO:0005739 mitochondrion", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A305-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZQW8-1", "uniprot_id": [ { "id": "D3ZQW8_RAT", "url": "https://www.uniprot.org/uniprot/D3ZQW8", "type": "external" } ], "mass": 160947.0, "length": 1576, "protein_name": "BRD4 interacting chromatin remodeling complex associated protein", "gene_name": "Bicra", "organism": "Rat", "refseq_name": "BRD4-interacting chromatin-remodeling complex-associated protein", "refseq_ac": [ { "id": "NP_001099696", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099696", "type": "external" } ], "gene_names_uniprotkb": "Bicra; Gltscr1", "gene_names_refseq": "Bicra; Gltscr1", "protein_names_uniprotkb": "BRD4 interacting chromatin remodeling complex associated protein", "protein_names_refseq": "BRD4 interacting chromatin remodelling complex associated protein; BRD4-interacting chromatin-remodeling complex-associated protein; glioma tumor suppressor candidate region gene 1", "tax_id": 10116, "disease": "Coffin-Siris syndrome 12 (Disease Ontology:DOID:0112370); Coffin-Siris syndrome (Disease Ontology:DOID:1925)", "pathway": " (rno:292622); (R-RNO-9933947)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 11, "predicted_n_glycosites": 0, "predicted_o_glycosites": 11, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 1, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 11, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0140537 transcription regulator activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0016514 SWI/SNF complex", "go_biological_process": "GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZQW8-1", "record_type": "protein", "filter_code": "0000000.1000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B2GV36-1", "uniprot_id": [ { "id": "S22AD_RAT", "url": "https://www.uniprot.org/uniprot/B2GV36", "type": "external" } ], "mass": 60691.0, "length": 551, "protein_name": "Solute carrier family 22 member 13", "gene_name": "LOC120094289; Slc22a13", "organism": "Rat", "refseq_name": "solute carrier family 22 member 13", "refseq_ac": [ { "id": "NP_001119757", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119757", "type": "external" } ], "gene_names_uniprotkb": "LOC120094289; Slc22a13; LOC120094289", "gene_names_refseq": "OAT10; ORCTL-3; Slc22a13", "protein_names_uniprotkb": "Solute carrier family 22 member 13; OAT10; ORCTL-3; Organic anion transporter 10; Organic cation transporter-like 3", "protein_names_refseq": "organic anion transporter 10; organic cation transporter-like 3; solute carrier family 22 (organic anion transporter), member 13; solute carrier family 22 (organic anion/urate transporter), member 13; solute carrier family 22 (organic cation transporter), member 13; solute carrier family 22 member 13", "tax_id": 10116, "disease": "", "pathway": " (rno:316062); (R-RNO-196807)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "18411268;24147638;35144162", "class_list": "", "function": "Anion antiporter that mediates the transport of nicotinate (PubMed:35144162). Possibly involved in nicotinate intestinal reabsorption (By similarity)., [UniProtKB, PubMed, UniProtKB]; Expression of SLC22A13 in basolateral membrane of renal collecting duct stimulates efflux of aspartate and glutamate., [RefSeq, PubMed]; SLC22A13 is a new urate and high affinity nicotinate transporter, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015143 urate transmembrane transporter activity;GO:0090416 nicotinate transmembrane transporter activity;GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0016324 apical plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0045922 negative regulation of fatty acid metabolic process;GO:2001142 nicotinate transport;GO:0015747 urate transport;GO:0002854 positive regulation of T cell mediated cytotoxicity directed against tumor cell target", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "B2GV36-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZQH1-1", "uniprot_id": [ { "id": "SRRM3_RAT", "url": "https://www.uniprot.org/uniprot/D3ZQH1", "type": "external" } ], "mass": 70923.0, "length": 648, "protein_name": "Serine/arginine repetitive matrix protein 3", "gene_name": "Srrm3", "organism": "Rat", "refseq_name": "serine/arginine repetitive matrix protein 3", "refseq_ac": [ { "id": "NP_001264323", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264323", "type": "external" } ], "gene_names_uniprotkb": "Srrm3", "gene_names_refseq": "RGD1307391; Srrm3", "protein_names_uniprotkb": "Serine/arginine repetitive matrix protein 3", "protein_names_refseq": "serine/arginine repetitive matrix protein 3", "tax_id": 10116, "disease": "", "pathway": " (rno:685890)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "36759540", "class_list": "", "function": "RNA splicing factor that regulates inclusion of microexons in mRNA transcripts (PubMed:36759540). Required for motor coordination. In cortical neurons, acts redundantly with SRRM4 and regulates many alternative splicing events, including inclusion of exon 4 into the transcriptional repressor REST transcript, leading to REST inactivation. REST inactivation de-represses potassium-chloride cotransporter 2/SLC12A5 expression, resulting in the switch in GABAergic neurotransmission from immature excitatory to inhibitory (By similarity). Regulates inclusion of a microexon in TBC1D24 in the brain cortex (By similarity). In pancreatic islets, mediates microexon inclusion. Regulates glucose- and amino acid-stimulated insulin secretion, as well as glucagon secretion (PubMed:36759540). Important for islet morphogenesis during pancreas development (By similarity). Regulates microexon inclusion in the developing retina, which is required for outer segment maintenance and vision (By similarity)., [UniProtKB, UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0046676 negative regulation of insulin secretion;GO:0008380 RNA splicing;GO:0070093 negative regulation of glucagon secretion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZQH1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B4F7A3-1", "uniprot_id": [ { "id": "B4F7A3_RAT", "url": "https://www.uniprot.org/uniprot/B4F7A3", "type": "external" } ], "mass": 37121.0, "length": 344, "protein_name": "Galectin", "gene_name": "Lgalsl", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Lgalsl", "gene_names_refseq": "", "protein_names_uniprotkb": "Galectin", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:360983)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "16641100;22673903", "class_list": "", "function": "Does not bind lactose, and may not bind carbohydrates., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030246 carbohydrate binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "B4F7A3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZE16-1", "uniprot_id": [ { "id": "D3ZE16_RAT", "url": "https://www.uniprot.org/uniprot/D3ZE16", "type": "external" } ], "mass": 75945.0, "length": 676, "protein_name": "Alpha-L-iduronidase", "gene_name": "Idua", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Idua; LOC100363795", "gene_names_refseq": "", "protein_names_uniprotkb": "Alpha-L-iduronidase; 3.2.1.76", "protein_names_refseq": "", "tax_id": 10116, "disease": "Scheie syndrome (Disease Ontology:DOID:0060222); mucopolysaccharidosis Ih/s (Disease Ontology:DOID:0111389); mucopolysaccharidosis Ih (Disease Ontology:DOID:0111390); otitis media (Disease Ontology:DOID:10754); gastric ulcer (Disease Ontology:DOID:10808); mucopolysaccharidosis I (Disease Ontology:DOID:12802)", "pathway": " (rno:360904); (R-RNO-2024096); (R-RNO-2024101)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.2.1.76", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.76", "type": "external" } ], "go_molecular_function": "GO:0003940 L-iduronidase activity;GO:0005102 signaling receptor binding", "go_cellular_component": "GO:0043202 lysosomal lumen;GO:0005615 extracellular space;GO:0005764 lysosome", "go_biological_process": "GO:0030209 dermatan sulfate proteoglycan catabolic process;GO:0005975 carbohydrate metabolic process;GO:0006027 glycosaminoglycan catabolic process;GO:0030200 heparan sulfate proteoglycan catabolic process;GO:0030211 heparin proteoglycan catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZE16-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZMB0-1", "uniprot_id": [ { "id": "D3ZMB0_RAT", "url": "https://www.uniprot.org/uniprot/D3ZMB0", "type": "external" } ], "mass": 216294.0, "length": 1932, "protein_name": "ADAM metallopeptidase with thrombospondin type 1 motif, 9", "gene_name": "Adamts9", "organism": "Rat", "refseq_name": "A disintegrin and metalloproteinase with thrombospondin motifs 9 precursor", "refseq_ac": [ { "id": "NP_001416065", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001416065", "type": "external" } ], "gene_names_uniprotkb": "Adamts9", "gene_names_refseq": "Adamts9", "protein_names_uniprotkb": "ADAM metallopeptidase with thrombospondin type 1 motif, 9", "protein_names_refseq": "A disintegrin and metalloproteinase with thrombospondin motifs 9 precursor; A disintegrin and metalloproteinase with thrombospondin motifs 9; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 9", "tax_id": 10116, "disease": "scoliosis (Disease Ontology:DOID:0060249); type 2 diabetes mellitus (Disease Ontology:DOID:9352); obesity (Disease Ontology:DOID:9970)", "pathway": " (rno:312566); (R-RNO-5173214)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "19348733", "class_list": "", "function": "Study indicates that ADAMTS-9 expression is modulated in response to cerebral ischaemia in vivo, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008270 zinc ion binding;GO:0004175 endopeptidase activity;GO:0008237 metallopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005783 endoplasmic reticulum;GO:0009986 cell surface;GO:0031012 extracellular matrix", "go_biological_process": "GO:0006508 proteolysis;GO:0030198 extracellular matrix organization;GO:0009617 response to bacterium;GO:0048593 camera-type eye morphogenesis;GO:0045636 positive regulation of melanocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZMB0-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K2I4-1", "uniprot_id": [ { "id": "A0A0G2K2I4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K2I4", "type": "external" } ], "mass": 108666.0, "length": 955, "protein_name": "Zinc finger protein 26", "gene_name": "Zfp26", "organism": "Rat", "refseq_name": "zinc finger protein 26 isoform X2", "refseq_ac": [ { "id": "XP_038937759", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038937759", "type": "external" } ], "gene_names_uniprotkb": "Zfp26", "gene_names_refseq": "RGD1565847; Zfp26", "protein_names_uniprotkb": "Zinc finger protein 26", "protein_names_refseq": "zinc finger protein 26 isoform X2", "tax_id": 10116, "disease": "", "pathway": " (rno:367033)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000976 transcription cis-regulatory region binding;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0016604 nuclear body", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K2I4-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZBP2-1", "uniprot_id": [ { "id": "D3ZBP2_RAT", "url": "https://www.uniprot.org/uniprot/D3ZBP2", "type": "external" } ], "mass": 145457.0, "length": 1277, "protein_name": "Paired amphipathic helix protein Sin3a", "gene_name": "Sin3a", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Sin3a", "gene_names_refseq": "", "protein_names_uniprotkb": "Paired amphipathic helix protein Sin3a; Histone deacetylase complex subunit Sin3a; Transcriptional corepressor Sin3a", "protein_names_refseq": "", "tax_id": 10116, "disease": "developmental disorder of mental health (Disease Ontology:DOID:0060037); chromosome 15q24 deletion syndrome (Disease Ontology:DOID:0060395); Huntington's disease (Disease Ontology:DOID:12858); cancer (Disease Ontology:DOID:162); transient cerebral ischemia (Disease Ontology:DOID:224)", "pathway": " (R-RNO-3899300); (R-RNO-400206); (R-RNO-8936459); (R-RNO-9022692); (R-RNO-9707564); (R-RNO-9824594); (R-RNO-9825892)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in the control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation. Cooperates with FOXK1 to regulate cell cycle progression probably by repressing cell cycle inhibitor genes expression. Required for cortical neuron differentiation and callosal axon elongation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003714 transcription corepressor activity;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding;GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005694 chromosome;GO:0032991 protein-containing complex;GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0048511 rhythmic process;GO:0051726 regulation of cell cycle;GO:0001701 in utero embryonic development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZBP2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K9R9-1", "uniprot_id": [ { "id": "A0A0G2K9R9_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K9R9", "type": "external" } ], "mass": 211185.0, "length": 1843, "protein_name": "Proteasome activator complex subunit 4", "gene_name": "Psme4", "organism": "Rat", "refseq_name": "proteasome activator complex subunit 4", "refseq_ac": [ { "id": "NP_001020311", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020311", "type": "external" } ], "gene_names_uniprotkb": "Psme4", "gene_names_refseq": "Psme4", "protein_names_uniprotkb": "Proteasome activator complex subunit 4; Proteasome activator PA200; Protein BLM10 homolog", "protein_names_refseq": "proteasome (prosome, macropain) activator subunit 4; proteasome activator complex subunit 4", "tax_id": 10116, "disease": "visceral heterotaxy (Disease Ontology:DOID:0050545)", "pathway": " (rno:498433)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP- and ubiquitin-independent degradation of core histones during spermatogenesis and DNA damage response. Recognizes and binds acetylated histones via its bromodomain-like (BRDL) region and activates the proteasome by opening the gated channel for substrate entry. Binds to the core proteasome via its C-terminus, which occupies the same binding sites as the proteasomal ATPases, opening the closed structure of the proteasome via an active gating mechanism. Component of the spermatoproteasome, a form of the proteasome specifically found in testis: binds to acetylated histones and promotes degradation of histones, thereby participating actively to the exchange of histones during spermatogenesis. Also involved in DNA damage response in somatic cells, by promoting degradation of histones following DNA double-strand breaks., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016504 peptidase activator activity;GO:0070628 proteasome binding", "go_cellular_component": "GO:1990111 spermatoproteasome complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0016607 nuclear speck", "go_biological_process": "GO:0006281 DNA repair;GO:0006974 DNA damage response;GO:0010499 proteasomal ubiquitin-independent protein catabolic process;GO:0035092 sperm DNA condensation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K9R9-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AC02-1", "uniprot_id": [ { "id": "D4AC02_RAT", "url": "https://www.uniprot.org/uniprot/D4AC02", "type": "external" } ], "mass": 107060.0, "length": 972, "protein_name": "Signal peptide, CUB and EGF-like domain-containing protein 2", "gene_name": "Scube2", "organism": "Rat", "refseq_name": "signal peptide, CUB and EGF-like domain-containing protein 2 precursor", "refseq_ac": [ { "id": "NP_001414533", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414533", "type": "external" } ], "gene_names_uniprotkb": "Scube2", "gene_names_refseq": "RGD1563998; Scube2-ps1; Scube2", "protein_names_uniprotkb": "Signal peptide, CUB and EGF-like domain-containing protein 2; Protein CEGP1; Scube/You", "protein_names_refseq": "signal peptide, CUB and EGF-like domain-containing protein 2 precursor; signal peptide, CUB and EGF-like domain-containing protein 2; signal peptide, CUB domain, EGF-like 2, pseudogene 1", "tax_id": 10116, "disease": "", "pathway": " (rno:499241); (R-RNO-5362798)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "31734396", "class_list": "", "function": "Matrix metalloproteinase-9 regulates the blood brain barrier via the hedgehog pathway in a rat model of traumatic brain injury., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0097108 hedgehog family protein binding;GO:0008289 lipid binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0009986 cell surface", "go_biological_process": "GO:0045880 positive regulation of smoothened signaling pathway;GO:0007165 signal transduction;GO:0045669 positive regulation of osteoblast differentiation;GO:1902732 positive regulation of chondrocyte proliferation;GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4AC02-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K1F8-1", "uniprot_id": [ { "id": "A0A0G2K1F8_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1F8", "type": "external" } ], "mass": 24503.0, "length": 225, "protein_name": "Membrane spanning 4-domains A7", "gene_name": "Ms4a7", "organism": "Rat", "refseq_name": "membrane-spanning 4-domains subfamily A member 7", "refseq_ac": [ { "id": "NP_001397220", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001397220", "type": "external" } ], "gene_names_uniprotkb": "Ms4a7", "gene_names_refseq": "Ms4a7", "protein_names_uniprotkb": "Membrane spanning 4-domains A7", "protein_names_refseq": "membrane-spanning 4-domains subfamily A member 7; membrane-spanning 4-domains, subfamily A, member 7", "tax_id": 10116, "disease": "", "pathway": " (rno:293744)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane;GO:0005802 trans-Golgi network", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K1F8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K4K6-1", "uniprot_id": [ { "id": "A0A0G2K4K6_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K4K6", "type": "external" } ], "mass": 139027.0, "length": 1241, "protein_name": "Erythroid differentiation regulatory factor 1", "gene_name": "Edrf1", "organism": "Rat", "refseq_name": "erythroid differentiation-related factor 1 isoform X2", "refseq_ac": [ { "id": "XP_008758111", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008758111", "type": "external" } ], "gene_names_uniprotkb": "Edrf1; RGD1306820", "gene_names_refseq": "Edrf1; RGD1306820", "protein_names_uniprotkb": "Erythroid differentiation regulatory factor 1", "protein_names_refseq": "erythroid differentiation-related factor 1 isoform X2", "tax_id": 10116, "disease": "", "pathway": " (rno:309069)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K4K6-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K7P2-1", "uniprot_id": [ { "id": "A0A0G2K7P2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K7P2", "type": "external" } ], "mass": 107008.0, "length": 950, "protein_name": "PHD finger protein 14", "gene_name": "Phf14", "organism": "Rat", "refseq_name": "PHD finger protein 14 isoform X1", "refseq_ac": [ { "id": "XP_006236166", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006236166", "type": "external" } ], "gene_names_uniprotkb": "Phf14", "gene_names_refseq": "Phf14; RGD1563764", "protein_names_uniprotkb": "PHD finger protein 14", "protein_names_refseq": "PHD finger protein 14 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:500030)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Histone-binding protein. Binds preferentially to unmodified histone H3 but can also bind to a lesser extent to histone H3 trimethylated at 'Lys-9' (H3K9me3) as well as to histone H3 monomethylated at 'Lys-27' (H3K27ac) and trimethylated at 'Lys-27' (H3K27me3). Represses PDGFRA expression, thus playing a role in regulation of mesenchymal cell proliferation. Suppresses the expression of CDKN1A/p21 by reducing the level of trimethylation of histone H3 'Lys-4', leading to enhanced proliferation of germinal center B cells., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042393 histone binding;GO:0140566 histone reader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005694 chromosome;GO:0000785 chromatin", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006338 chromatin remodeling;GO:0006357 regulation of transcription by RNA polymerase II;GO:0008285 negative regulation of cell population proliferation;GO:0048286 lung alveolus development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K7P2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K7H6-1", "uniprot_id": [ { "id": "A0A0G2K7H6_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K7H6", "type": "external" } ], "mass": 38815.0, "length": 347, "protein_name": "Serpin B12", "gene_name": "Serpinb8", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Serpinb8", "gene_names_refseq": "", "protein_names_uniprotkb": "Serpin B12", "protein_names_refseq": "", "tax_id": 10116, "disease": "peeling skin syndrome 5 (Disease Ontology:DOID:0070524)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Inhibits trypsin and plasmin, but not thrombin, coagulation factor Xa, or urokinase-type plasminogen activator. May play a role in cell differentiation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005829 cytosol", "go_biological_process": "GO:0010951 negative regulation of endopeptidase activity;GO:0090136 epithelial cell-cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K7H6-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K4K0-1", "uniprot_id": [ { "id": "A0A0G2K4K0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K4K0", "type": "external" } ], "mass": 189862.0, "length": 1751, "protein_name": "Ras-responsive element-binding protein 1", "gene_name": "Rreb1", "organism": "Rat", "refseq_name": "ras-responsive element-binding protein 1 isoform X1", "refseq_ac": [ { "id": "XP_006253876", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006253876", "type": "external" } ], "gene_names_uniprotkb": "Rreb1", "gene_names_refseq": "Rreb1", "protein_names_uniprotkb": "Ras-responsive element-binding protein 1", "protein_names_refseq": "ras-responsive element-binding protein 1 isoform X1", "tax_id": 10116, "disease": "RASopathy (Disease Ontology:DOID:0080690)", "pathway": " (rno:306873)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0016607 nuclear speck;GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0051094 positive regulation of developmental process;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K4K0-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A303-1", "uniprot_id": [ { "id": "D4A303_RAT", "url": "https://www.uniprot.org/uniprot/D4A303", "type": "external" } ], "mass": 67923.0, "length": 619, "protein_name": "CBFA2/RUNX1 partner transcriptional co-repressor 3", "gene_name": "Cbfa2t3", "organism": "Rat", "refseq_name": "protein CBFA2T3", "refseq_ac": [ { "id": "NP_001101923", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101923", "type": "external" } ], "gene_names_uniprotkb": "Cbfa2t3", "gene_names_refseq": "Cbfa2t3", "protein_names_uniprotkb": "CBFA2/RUNX1 partner transcriptional co-repressor 3", "protein_names_refseq": "CBFA2/RUNX1 translocation partner 3; core-binding factor, runt domain, alpha subunit 2; protein CBFA2T3; translocated to, 3", "tax_id": 10116, "disease": "", "pathway": " (rno:361431)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, 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"GO:0006351 DNA-templated transcription;GO:0030851 granulocyte differentiation;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0008285 negative regulation of cell population proliferation;GO:0001666 response to hypoxia", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A303-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1W2Q6P4-1", "uniprot_id": [ { "id": "A0A1W2Q6P4_RAT", "url": "https://www.uniprot.org/uniprot/A0A1W2Q6P4", "type": "external" } ], "mass": 47926.0, "length": 429, "protein_name": "Queuine tRNA-ribosyltransferase accessory subunit 2", "gene_name": "Qtrt2", "organism": "Rat", "refseq_name": "queuine tRNA-ribosyltransferase accessory subunit 2 isoform X1", "refseq_ac": [ { "id": "XP_008766981", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008766981", "type": "external" } ], "gene_names_uniprotkb": "Qtrt2; QTRT2", "gene_names_refseq": "Qtrt2; Qtrtd1", "protein_names_uniprotkb": "Queuine tRNA-ribosyltransferase accessory subunit 2; Queuine tRNA-ribosyltransferase domain-containing protein 1", "protein_names_refseq": "queuine tRNA-ribosyltransferase accessory subunit 2 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:288364)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, 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"go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0046872 metal ion binding;GO:0046982 protein heterodimerization activity;GO:0008479 tRNA-guanosine(34) queuine transglycosylase activity;GO:0140767 enzyme-substrate adaptor activity", "go_cellular_component": "GO:1990234 transferase complex;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0032991 protein-containing complex;GO:0032473 cytoplasmic side of mitochondrial outer membrane", "go_biological_process": "GO:0002099 tRNA wobble guanine modification;GO:0006400 tRNA modification", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1W2Q6P4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K1F7-1", "uniprot_id": [ { "id": "A0A0G2K1F7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1F7", "type": "external" } ], "mass": 395569.0, "length": 3512, "protein_name": "Unconventional myosin-XV", "gene_name": "Myo15a", "organism": "Rat", "refseq_name": "unconventional myosin-XV", "refseq_ac": [ { "id": "NP_001414755", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414755", "type": "external" } ], "gene_names_uniprotkb": "Myo15a", "gene_names_refseq": "Myo15a; Myo15; RGD1561873", "protein_names_uniprotkb": "Unconventional myosin-XV; Unconventional myosin-15", "protein_names_refseq": "myosin XV; unconventional myosin-XV-like; unconventional myosin-XV", "tax_id": 10116, "disease": "autosomal recessive nonsyndromic deafness 3 (Disease Ontology:DOID:0110488); sensorineural hearing loss (Disease Ontology:DOID:10003); blindness (Disease Ontology:DOID:1432)", "pathway": " (rno:501699)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "14629112;21479269", "class_list": "", "function": "Mutations in binding domains of myosin XV do not only cause non-syndromic hearing loss but can also lead to syndromic disorders including retinal dysfunction. Publication Status: Online-Only, [RefSeq, PubMed]; Myo15 and Kcnj12 can be regarded as candidate genes for the deafblind phenotype of the LEW-ci2 rat., [RefSeq, PubMed]; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Required for the arrangement of stereocilia in mature hair bundles., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0005524 ATP binding;GO:0003774 cytoskeletal motor activity;GO:0051015 actin filament binding;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0032420 stereocilium;GO:0016459 myosin complex;GO:0005737 cytoplasm;GO:0015629 actin cytoskeleton;GO:0016020 membrane", "go_biological_process": "GO:0007605 sensory perception of sound;GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0007626 locomotory behavior;GO:0042472 inner ear morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2K1F7-1", "record_type": "protein", "filter_code": "0000000.0000111.001000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A802-1", "uniprot_id": [ { "id": "D4A802_RAT", "url": "https://www.uniprot.org/uniprot/D4A802", "type": "external" } ], "mass": 8390.0, "length": 76, "protein_name": "Small proline rich protein 2F", "gene_name": "Sprr2f", "organism": "Rat", "refseq_name": "uncharacterized protein LOC102550416", "refseq_ac": [ { "id": "NP_001395841", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001395841", "type": "external" } ], "gene_names_uniprotkb": "Sprr2f", "gene_names_refseq": "Sprr2f", "protein_names_uniprotkb": "Small proline rich protein 2F", "protein_names_refseq": "small proline-rich protein 2I-like; 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RGD1308759", "protein_names_uniprotkb": "MAU2 chromatid cohesion factor homolog; Cohesin loading complex subunit SCC4 homolog", "protein_names_refseq": "MAU2 chromatid cohesion factor homolog isoform 1; Mau2 chromatid cohesion factor homolog", "tax_id": 10116, "disease": "", "pathway": " (rno:290668); (R-RNO-2470946)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0061775 cohesin loader activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005634 nucleus;GO:0016604 nuclear body;GO:0000785 chromatin;GO:0032116 SMC loading complex", "go_biological_process": "GO:0007059 chromosome segregation;GO:0051301 cell division;GO:0007064 mitotic sister chromatid cohesion;GO:0034088 maintenance of mitotic sister chromatid cohesion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3Z8G8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K0K4-1", "uniprot_id": [ { "id": "A0A0G2K0K4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K0K4", "type": "external" } ], "mass": 34542.0, "length": 307, "protein_name": "Olfactory receptor", "gene_name": "Or8g2", "organism": "Rat", "refseq_name": "olfactory receptor Olr1328", "refseq_ac": [ { "id": "NP_001000599", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000599", "type": "external" } ], "gene_names_uniprotkb": "Or8g2", "gene_names_refseq": "Olr1328; Or8g2", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1328; olfactory receptor Olr1328; olfactory receptor gene Olr1328", "tax_id": 10116, "disease": "", "pathway": " (rno:367067)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 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"total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003823 antigen binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0019814 immunoglobulin complex", "go_biological_process": "GO:0016064 immunoglobulin mediated immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K0W7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K1A9-1", "uniprot_id": [ { "id": "A0A0G2K1A9_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1A9", "type": "external" } ], "mass": 80916.0, "length": 723, "protein_name": "Nucleolar protein 11", "gene_name": "Nol11", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Nol11", "gene_names_refseq": "", "protein_names_uniprotkb": "Nucleolar protein 11", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-6791226)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, 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true }, { "uniprot_canonical_ac": "A1EC97-1", "uniprot_id": [ { "id": "A1EC97_RAT", "url": "https://www.uniprot.org/uniprot/A1EC97", "type": "external" } ], "mass": 22267.0, "length": 198, "protein_name": "Dual specificity phosphatase 14", "gene_name": "Dusp14", "organism": "Rat", "refseq_name": "dual specificity protein phosphatase 14", "refseq_ac": [ { "id": "NP_001073362", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073362", "type": "external" } ], "gene_names_uniprotkb": "Dusp14", "gene_names_refseq": "Dusp14l2; Dusp14", "protein_names_uniprotkb": "Dual specificity phosphatase 14", "protein_names_refseq": "dual specificity phosphatase 14-like 2; dual specificity protein phosphatase 14", "tax_id": 10116, "disease": "chromosome 17q12 deletion syndrome (Disease Ontology:DOID:0060404); pulmonary tuberculosis (Disease Ontology:DOID:2957)", "pathway": " (rno:360580)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29860460;34605731", "class_list": "", 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"go_biological_process": "GO:0090263 positive regulation of canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A7YY82-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B0BN40-1", "uniprot_id": [ { "id": "B0BN40_RAT", "url": "https://www.uniprot.org/uniprot/B0BN40", "type": "external" } ], "mass": 39363.0, "length": 344, "protein_name": "Rho guanine nucleotide exchange factor 39", "gene_name": "Arhgef39", "organism": "Rat", "refseq_name": "rho guanine nucleotide exchange factor 39", "refseq_ac": [ { "id": "NP_001100146", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100146", "type": "external" } ], "gene_names_uniprotkb": "Arhgef39", "gene_names_refseq": "Arhgef39; RGD1310376", "protein_names_uniprotkb": "Rho guanine nucleotide exchange factor 39", "protein_names_refseq": "Rho guanine nucleotide exchange factor (GEF) 39; rho guanine nucleotide exchange factor 39; vav-like protein C9orf100 homolog", "tax_id": 10116, "disease": "", "pathway": " (rno:298404); (R-RNO-193648); (R-RNO-416482); (R-RNO-9013149)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Promotes cell proliferation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, 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"https://www.uniprot.org/uniprot/B0BN83", "type": "external" } ], "mass": 31204.0, "length": 282, "protein_name": "Armadillo repeat-containing protein 1", "gene_name": "Armc1", "organism": "Rat", "refseq_name": "armadillo repeat-containing protein 1", "refseq_ac": [ { "id": "NP_001099895", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099895", "type": "external" } ], "gene_names_uniprotkb": "Armc1", "gene_names_refseq": "Armc1; RGD1560393", "protein_names_uniprotkb": "Armadillo repeat-containing protein 1", "protein_names_refseq": "armadillo repeat-containing protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:294948)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F7F379", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0005829 cytosol", "go_biological_process": "GO:0048312 intracellular distribution of mitochondria", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "B0BN83-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B0BNK1-1", "uniprot_id": [ { "id": "B0BNK1_RAT", "url": "https://www.uniprot.org/uniprot/B0BNK1", "type": "external" } ], "mass": 23426.0, "length": 216, "protein_name": "small monomeric GTPase", "gene_name": "Rab5c", "organism": "Rat", "refseq_name": "ras-related protein Rab-5C", "refseq_ac": [ { "id": "NP_001099310", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099310", "type": "external" } ], "gene_names_uniprotkb": "Rab5c", "gene_names_refseq": "Rab5c", "protein_names_uniprotkb": "small monomeric GTPase; 3.6.5.2", "protein_names_refseq": "ras-related protein Rab-5C", "tax_id": 10116, "disease": "cancer (Disease Ontology:DOID:162); carcinoma (Disease Ontology:DOID:305); kidney disease (Disease Ontology:DOID:557)", "pathway": " (rno:287709); (R-RNO-432722); (R-RNO-6798695); (R-RNO-8856828); (R-RNO-8873719); (R-RNO-8876198)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "38843836", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, 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"3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "7.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.1", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "3.1.3.86", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.86", "type": "external" }, { "id": "3.1.3.56", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.56", "type": "external" }, { "id": "3.1.3.36", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.36", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "3.4.16.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.16.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "2.5.1.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.18", "type": "external" }, { "id": "3.1.3.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.5", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "3.4.23.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.23.-", "type": "external" }, { "id": "2.5.1.60", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.60", "type": "external" }, { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" }, { "id": "2.3.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.23", "type": "external" }, { "id": "2.3.1.67", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.67", "type": "external" }, { "id": "2.3.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.25", "type": "external" }, { "id": "3.2.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.25", "type": "external" }, { "id": "3.5.1.92", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.92", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" }, { "id": "3.2.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.20", "type": "external" }, { "id": "3.4.17.22", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.17.22", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0019003 GDP binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0005768 endosome;GO:0005769 early endosome;GO:0005811 lipid droplet;GO:0005886 plasma membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006897 endocytosis;GO:0030100 regulation of endocytosis;GO:0007032 endosome organization;GO:0016197 endosomal transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "B0BNK1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B0K037-1", "uniprot_id": [ { "id": "B0K037_RAT", "url": "https://www.uniprot.org/uniprot/B0K037", "type": "external" } ], "mass": 25498.0, "length": 228, "protein_name": "General transcription factor 3C polypeptide 6", "gene_name": "Gtf3c6", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Gtf3c6", "gene_names_refseq": "", "protein_names_uniprotkb": "General transcription factor 3C polypeptide 6; Transcription factor IIIC 35 kDa subunit; Transcription factor IIIC subunit 6", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:361858); (R-RNO-76061); (R-RNO-76066)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0000995 RNA polymerase III general transcription initiation factor activity", "go_cellular_component": "GO:0000127 transcription factor TFIIIC complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0016604 nuclear body", "go_biological_process": "GO:0006383 transcription by RNA polymerase III;GO:0006384 transcription initiation at RNA polymerase III promoter", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B0K037-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B1H291-1", "uniprot_id": [ { "id": "B1H291_RAT", "url": "https://www.uniprot.org/uniprot/B1H291", "type": "external" } ], "mass": 70500.0, "length": 637, "protein_name": "Testicular spindle-associated protein SHCBP1L", "gene_name": "Shcbp1l", "organism": "Rat", "refseq_name": "testicular spindle-associated protein SHCBP1L", "refseq_ac": [ { "id": "NP_001099431", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099431", "type": "external" } ], "gene_names_uniprotkb": "Shcbp1l", "gene_names_refseq": "RGD1305609; Shcbp1l", "protein_names_uniprotkb": "Testicular spindle-associated protein SHCBP1L; SHC SH2 domain-binding protein 1-like protein", "protein_names_refseq": "SHC SH2 domain-binding protein 1-like protein; SHC SH2-domain binding protein 1-like; testicular spindle-associated protein SHCBP1L", "tax_id": 10116, "disease": "", "pathway": " (rno:289101)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Testis-specific spindle-associated factor that plays a role in spermatogenesis. In association with HSPA2, participates in the maintenance of spindle integrity during meiosis in male germ cells., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0072687 meiotic spindle;GO:0005819 spindle", "go_biological_process": "GO:2001252 positive regulation of chromosome organization;GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0007112 male meiosis cytokinesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "B1H291-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B1WBV4-1", "uniprot_id": [ { "id": "B1WBV4_RAT", "url": "https://www.uniprot.org/uniprot/B1WBV4", "type": "external" } ], "mass": 27741.0, "length": 249, "protein_name": "Pleckstrin homology domain-containing family F member 2", "gene_name": "Plekhf2", "organism": "Rat", "refseq_name": "pleckstrin homology domain-containing family F member 2", "refseq_ac": [ { "id": "NP_001102125", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102125", "type": "external" } ], "gene_names_uniprotkb": "Plekhf2", "gene_names_refseq": "Plekhf2", "protein_names_uniprotkb": "Pleckstrin homology domain-containing family F member 2", "protein_names_refseq": "pleckstrin homology domain containing, family F (with FYVE domain) member 2; pleckstrin homology domain-containing family F member 2", "tax_id": 10116, "disease": "", "pathway": " (rno:362484)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0035091 phosphatidylinositol binding", "go_cellular_component": "GO:0005769 early endosome;GO:0005783 endoplasmic reticulum;GO:0031901 early endosome membrane;GO:0030133 transport vesicle", "go_biological_process": "GO:0015031 protein transport;GO:0007032 endosome organization;GO:0008333 endosome to lysosome transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "B1WBV4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B1WC05-1", "uniprot_id": [ { "id": "B1WC05_RAT", "url": "https://www.uniprot.org/uniprot/B1WC05", "type": "external" } ], "mass": 52781.0, "length": 461, "protein_name": "Box C/D snoRNA protein 1", "gene_name": "Znhit6", "organism": "Rat", "refseq_name": "box C/D snoRNA protein 1", "refseq_ac": [ { "id": "NP_001099673", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099673", "type": "external" } ], "gene_names_uniprotkb": "Znhit6", "gene_names_refseq": "RGD1308723; Znhit6", "protein_names_uniprotkb": "Box C/D snoRNA protein 1; Zinc finger HIT domain-containing protein 6", "protein_names_refseq": "box C/D snoRNA protein 1; zinc finger, HIT type 6", "tax_id": 10116, "disease": "", "pathway": " (rno:292160)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0019899 enzyme binding;GO:0042802 identical protein binding;GO:0051117 ATPase binding;GO:0001094 TFIID-class transcription factor complex binding", "go_cellular_component": "GO:0070761 pre-snoRNP complex;GO:0005634 nucleus", "go_biological_process": "GO:0051259 protein complex oligomerization;GO:0042254 ribosome biogenesis;GO:0000492 box C/D snoRNP assembly;GO:0048254 snoRNA localization;GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "B1WC05-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B1WC49-1", "uniprot_id": [ { "id": "B1WC49_RAT", "url": "https://www.uniprot.org/uniprot/B1WC49", "type": "external" } ], "mass": 59020.0, "length": 524, "protein_name": "Apoptosis inhibitor 5", "gene_name": "Api5", "organism": "Rat", "refseq_name": "apoptosis inhibitor 5 isoform 1", "refseq_ac": [ { "id": "NP_001386658", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386658", "type": "external" } ], "gene_names_uniprotkb": "Api5", "gene_names_refseq": "Api5", "protein_names_uniprotkb": "Apoptosis inhibitor 5", "protein_names_refseq": "apoptosis inhibitor 5 isoform 1", "tax_id": 10116, "disease": "", "pathway": " (rno:362170)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0017134 fibroblast growth factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck;GO:0005681 spliceosomal complex", "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "B1WC49-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B1WC52-1", "uniprot_id": [ { "id": "B1WC52_RAT", "url": "https://www.uniprot.org/uniprot/B1WC52", "type": "external" } ], "mass": 53045.0, "length": 469, "protein_name": "E3 ubiquitin-protein ligase TRAIP", "gene_name": "Traip", "organism": "Rat", "refseq_name": "E3 ubiquitin-protein ligase TRAIP", "refseq_ac": [ { "id": "NP_001102474", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102474", "type": "external" } ], "gene_names_uniprotkb": "Traip", "gene_names_refseq": "Traip", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase TRAIP; 2.3.2.27; TRAF-interacting protein", "protein_names_refseq": "E3 ubiquitin-protein ligase TRAIP", "tax_id": 10116, "disease": "Seckel syndrome 9 (Disease Ontology:DOID:0070005)", "pathway": " (rno:367167); (R-RNO-983168)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "2.3.2.32", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.32", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "2.3.2.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.24", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0042802 identical protein binding;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0048471 perinuclear region of cytoplasm;GO:0090734 site of DNA damage", "go_biological_process": "GO:0006281 DNA repair;GO:0007165 signal transduction;GO:0016567 protein ubiquitination;GO:0031297 replication fork processing;GO:0006974 DNA damage response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B1WC52-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B1WC61-1", "uniprot_id": [ { "id": "ACAD9_RAT", "url": "https://www.uniprot.org/uniprot/B1WC61", "type": "external" } ], "mass": 68843.0, "length": 625, "protein_name": "Complex I assembly factor ACAD9, mitochondrial", "gene_name": "Acad9", "organism": "Rat", "refseq_name": "complex I assembly factor ACAD9, mitochondrial", "refseq_ac": [ { "id": "NP_861433", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_861433", "type": "external" } ], "gene_names_uniprotkb": "Acad9", "gene_names_refseq": "ACAD-9; Acad9; Nyggf2", "protein_names_uniprotkb": "Complex I assembly factor ACAD9, mitochondrial; 1.3.8.7; 1.3.8.8; ACAD-9; Acyl-CoA dehydrogenase family member 9", "protein_names_refseq": "acyl-CoA dehydrogenase family member 9, mitochondrial; acyl-Coenzyme A dehydrogenase family, member 9; complex I assembly factor ACAD9, mitochondrial", "tax_id": 10116, "disease": "nuclear type mitochondrial complex I deficiency 20 (Disease Ontology:DOID:0112072)", "pathway": " (rno:294973); (R-RNO-6799198)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "18385088;22982022;28084602;38843836", "class_list": "", "function": "Accumulation of 3-hydroxylated intermediates of long-chain fatty acids may contribute to the pathogenesis of retinopathy in MTP deficiencies., [RefSeq, PubMed]; Results suggested that Glu389 could function as the catalytic base that abstracted the alpha-proton of the acyl-CoA substrate in a proposed catalytic mechanism., [RefSeq, PubMed]; Together with NDUFAF1 and ECSIT, forms part of the mitochondrial complex I (MCIA),which is required for the biogenesis of respiratory Complex I (CI) and is therefore crucial for the activation of the oxidative phosphorylation system. ECSIT binding triggers a large conformational change, switching ACAD9 from a fatty acid oxidation (FAO) enzyme to a CI assembly factor. The function in CI assembly is independent of the fatty acid oxidation (FAO) activity of the protein. As FAO enzyme, it catalyzes the first step in mitochondrial FAO, which consists in the proR-proR stereospecific alpha, beta-dehydrogenation of fatty acyl-CoA thioesters using the electron transfer flavoprotein (ETF) as their physiologic electron acceptor, resulting in the formation of trans-2-enoyl-CoA ((2E)-enoyl-CoA). Its preferred substrates are both saturated and unsaturated long-chain acyl-CoA substrates, with optimum activity toward the latter. In addition, based on its established catalytic mechanism, and combined genetic interaction or mutant phenotype evidence, it is predicted to act also on substrates that have not been tested experimentally but are metabolized by mitochondrial FAO, including long-chain unsaturated fatty acids such as linoleate (9Z,12Z-octadecadienoate), linolenate (9Z,12Z,15Z-octadecatrienoate), and others. Among the different mitochondrial acyl-CoA dehydrogenases, its FAO activity overlaps with that of ACADV and ACADL, but plays a primary role in tissues where it is the main long-chain ACAD expressed. It differs significantly from ACADVL in the use of polyunsaturated substrates in vitro, especially docosahexaenoic acid (which is not primarily used for energy but mainly beta-oxidized in the peroxisomes)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, 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"https://www.rhea-db.org/rhea/?query=ec:2.1.1.320", "type": "external" } ], "go_molecular_function": "GO:0003995 acyl-CoA dehydrogenase activity;GO:0004466 long-chain fatty acyl-CoA dehydrogenase activity;GO:0050660 flavin adenine dinucleotide binding;GO:0070991 medium-chain fatty acyl-CoA dehydrogenase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0030425 dendrite;GO:0031966 mitochondrial membrane;GO:0160295 mitochondrial complex I intermediate assembly complex", "go_biological_process": "GO:0046395 carboxylic acid catabolic process;GO:0001676 long-chain fatty acid metabolic process;GO:0032981 mitochondrial respiratory chain complex I assembly;GO:0051791 medium-chain fatty acid metabolic process;GO:0006631 fatty acid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "B1WC61-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B1WC74-1", "uniprot_id": [ { "id": "B1WC74_RAT", "url": "https://www.uniprot.org/uniprot/B1WC74", "type": "external" } ], "mass": 17642.0, "length": 159, "protein_name": "EP300 interacting inhibitor of differentiation 1", "gene_name": "Eid1", "organism": "Rat", "refseq_name": "EP300-interacting inhibitor of differentiation 1", "refseq_ac": [ { "id": "NP_001102675", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102675", "type": "external" } ], "gene_names_uniprotkb": "Eid1", "gene_names_refseq": "Eid1; RGD1562702", "protein_names_uniprotkb": "EP300 interacting inhibitor of differentiation 1", "protein_names_refseq": "EP300-interacting inhibitor of differentiation 1", "tax_id": 10116, "disease": "", "pathway": " (rno:499882)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, 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"https://www.ncbi.nlm.nih.gov/protein/NP_001102781", "type": "external" } ], "gene_names_uniprotkb": "Mab21l4; RGD1563692", "gene_names_refseq": "Mab21l4; RGD1563692", "protein_names_uniprotkb": "Mab-21 like 4", "protein_names_refseq": "protein mab-21-like 4; uncharacterized protein C2orf54 homolog", "tax_id": 10116, "disease": "", "pathway": " (rno:501185)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, 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"url": "https://www.uniprot.org/uniprot/B1WC89", "type": "external" } ], "mass": 35984.0, "length": 328, "protein_name": "Sosondowah ankyrin repeat domain family member D", "gene_name": "Sowahd", "organism": "Rat", "refseq_name": "ankyrin repeat domain-containing protein SOWAHD", "refseq_ac": [ { "id": "NP_001166844", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001166844", "type": "external" } ], "gene_names_uniprotkb": "Sowahd", "gene_names_refseq": "Ankrd58; RGD1563086; Sowahd", "protein_names_uniprotkb": "Sosondowah ankyrin repeat domain family member D", "protein_names_refseq": "ankyrin repeat domain 58; ankyrin repeat domain-containing protein 58; ankyrin repeat domain-containing protein SOWAHD", "tax_id": 10116, "disease": "", "pathway": " (rno:367699)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, 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"ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B1WC89-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B1WC90-1", "uniprot_id": [ { "id": "B1WC90_RAT", "url": "https://www.uniprot.org/uniprot/B1WC90", "type": "external" } ], "mass": 53489.0, "length": 470, "protein_name": "TNF receptor-associated factor", "gene_name": "Traf4", "organism": "Rat", "refseq_name": "TNF receptor-associated factor 4", "refseq_ac": [ { "id": "NP_001100487", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100487", "type": "external" } ], "gene_names_uniprotkb": "Traf4", "gene_names_refseq": "Traf4", "protein_names_uniprotkb": "TNF receptor-associated factor", "protein_names_refseq": "TNF receptor-associated factor 4", "tax_id": 10116, "disease": "lung adenocarcinoma (Disease Ontology:DOID:3910)", "pathway": " (rno:303285)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "22673903;37642020", "class_list": "", "function": "TRAF Family Member 4 Promotes Cardiac Hypertrophy Through the Activation of the AKT Pathway., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, 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system", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "B1WC90-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B2GUV6-1", "uniprot_id": [ { "id": "B2GUV6_RAT", "url": "https://www.uniprot.org/uniprot/B2GUV6", "type": "external" } ], "mass": 54474.0, "length": 480, "protein_name": "Sestrin 2", "gene_name": "Sesn2", "organism": "Rat", "refseq_name": "sestrin-2", "refseq_ac": [ { "id": "NP_001102828", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102828", "type": "external" } ], "gene_names_uniprotkb": "Sesn2", "gene_names_refseq": "RGD1566319; Sesn2", "protein_names_uniprotkb": "Sestrin 2", "protein_names_refseq": "sestrin-2", "tax_id": 10116, "disease": "", "pathway": " (rno:502988); (R-RNO-5628897); (R-RNO-9639288); (R-RNO-9755511)", "pathway_count": 4, "publication_count": 6, "publication_id_list": "19430206;31085280;31199952;32275923;32526292;38666564", "class_list": "", "function": "SESN2 protected against Dox-induced cardiotoxicity through improving mitochondria function and mitophagy. These results established SESN2 as a key player in mitochondrial function and provided a potential therapeutic approach to Dox-induced cardiomyopathy., [RefSeq, PubMed]; Sestrin 2 overexpression alleviates hydrogen peroxide-induced apoptosis and oxidative stress in rat retinal ganglion cells by downregulating Keap1 and reinforcing activation of Nrf2/antioxidant response element signaling., [RefSeq, PubMed]; Sestrin2 overexpression activates the Nrf2/HO-1 pathway, leading to enhanced angiogenesis following cerebral ischemia., [RefSeq, PubMed]; Sestrin2 promotes angiogenesis to alleviate brain injury by activating Nrf2 through regulating the interaction between p62 and Keap1 following photothrombotic stroke in rats., [RefSeq, PubMed]; The impact of sestrin2 on reactive oxygen species in diabetic retinopathy., [RefSeq, PubMed]; The importance of histone acetylation in the regulation of Srxn1 and Sesn2, to understand more about how these genes are regulated by synaptic activity was investigated., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3ZFT9", "ec_number_list": [], "go_molecular_function": "GO:0044877 protein-containing complex binding;GO:0016684 oxidoreductase activity, acting on peroxide as acceptor;GO:0005092 GDP-dissociation inhibitor activity;GO:0032542 sulfiredoxin activity;GO:0042731 PH domain binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005765 lysosomal membrane;GO:0031588 nucleotide-activated protein kinase complex", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0006635 fatty acid beta-oxidation;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0072659 protein localization to plasma membrane;GO:0032147 activation of protein kinase activity", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "B2GUV6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B2GUV8-1", "uniprot_id": [ { "id": "B2GUV8_RAT", "url": "https://www.uniprot.org/uniprot/B2GUV8", "type": "external" } ], "mass": 78865.0, "length": 707, "protein_name": "BCL6, transcription repressor", "gene_name": "Bcl6", "organism": "Rat", "refseq_name": "B-cell lymphoma 6 protein", "refseq_ac": [ { "id": "NP_001100554", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100554", "type": "external" } ], "gene_names_uniprotkb": "Bcl6", "gene_names_refseq": "Bcl6", "protein_names_uniprotkb": "BCL6, transcription repressor", "protein_names_refseq": "B-cell CLL/lymphoma 6; B-cell leukemia/lymphoma 6; B-cell lymphoma 6 protein", "tax_id": 10116, "disease": "diffuse large B-cell lymphoma (Disease Ontology:DOID:0050745); B-cell lymphoma (Disease Ontology:DOID:707)", "pathway": " (rno:303836)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "22673903;29972264;30805081;31346987", "class_list": "", "function": "BCL6 attenuates proliferation and oxidative stress of vascular smooth muscle cells in hypertension. Publication Status: Online-Only, [RefSeq, PubMed]; Bcl6 may participate in the maintenance of cardiomyocyte balance. Bcl6 deficiency disrupts this balance, causing inflammation, oxidative stress, and apoptosis in cardiomyocytes and aggregates in hypoxia-induced cardiomyocyte injury., [RefSeq, PubMed]; The results showed that Bcl6 overexpression induced decreased proliferation and reduced activation of fibroblasts which were stimulated with TGFb1. It was found that activated smad2 and smad3 were not changed by overexpressing Bcl6, but smad4 was decreased., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005657 replication fork;GO:0042382 paraspeckles", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006954 inflammatory response;GO:0007283 spermatogenesis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "B2GUV8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B2GV39-1", "uniprot_id": [ { "id": "B2GV39_RAT", "url": "https://www.uniprot.org/uniprot/B2GV39", "type": "external" } ], "mass": 66231.0, "length": 576, "protein_name": "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B", "gene_name": "Mgat4b", "organism": "Rat", "refseq_name": "alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B isoform X1", "refseq_ac": [ { "id": "XP_006246312", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006246312", "type": "external" } ], "gene_names_uniprotkb": "Mgat4b", "gene_names_refseq": "Mgat4b; 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Binds the stem-loop structure of replication-dependent histone pre-mRNAs and contributes to efficient 3'-end processing by stabilizing the complex between histone pre-mRNA and U7 small nuclear ribonucleoprotein (snRNP), via the histone downstream element (HDE). Plays an important role in targeting mature histone mRNA from the nucleus to the cytoplasm and to the translation machinery. Stabilizes mature histone mRNA and could be involved in cell-cycle regulation of histone gene expression. Involved in the mechanism by which growing oocytes accumulate histone proteins that support early embryogenesis. 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CD2 antigen cytoplasmic tail-binding protein 2", "tax_id": 10116, "disease": "", "pathway": " (rno:293505)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Involved in pre-mRNA splicing as component of the U5 snRNP complex that is involved in spliceosome assembly., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043021 ribonucleoprotein complex binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0016607 nuclear speck;GO:0005681 spliceosomal complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0008380 RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "B4F786-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B5DF62-1", "uniprot_id": [ { "id": "B5DF62_RAT", "url": "https://www.uniprot.org/uniprot/B5DF62", "type": "external" } ], "mass": 64750.0, "length": 593, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Pak4", "organism": "Rat", "refseq_name": "serine/threonine-protein kinase PAK 4", "refseq_ac": [ { "id": "NP_001099708", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099708", "type": "external" } ], "gene_names_uniprotkb": "Pak4", "gene_names_refseq": "Pak4", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "p21 (CDKN1A)-activated kinase 4; p21 protein (Cdc42/Rac)-activated kinase 4; p21-activated kinase 4; serine/threonine-protein kinase PAK 4", "tax_id": 10116, "disease": "Parkinson's disease (Disease Ontology:DOID:14330); clear cell renal cell carcinoma (Disease Ontology:DOID:4467)", "pathway": " (rno:292756); (R-RNO-9013149); (R-RNO-9013404); (R-RNO-9013406); (R-RNO-9013407); (R-RNO-9013408); (R-RNO-9013420); (R-RNO-9013423); (R-RNO-9013424)", "pathway_count": 9, "publication_count": 5, "publication_id_list": "16641100;22673903;27903866;29445744;31984786", "class_list": "", "function": "In pancreatic acinar cells, activation of focal adhesion kinases (p125(FAK),PYK2) and its accompanying adapter proteins, p130CAS/paxillin; Mek1/2, p44/42, GSK3, and beta-catenin are mediated by PAK4., [RefSeq, PubMed]; In summary, PAK4 is a key regulator in the pathophysiological process of acute lung injury (ALI) and can be a useful target for ALI treatment., [RefSeq, PubMed]; PAK4 activity was markedly decreased in postmortem brain tissue from Parkinson's disease (PD) patients and in rodent models of PD. Expression of constitutively active PAK4(S445N/S474E) (caPAK4) protected DA neurons in both the 6-hydroxydopamine and alpha-synuclein rat models of PD and preserved motor function., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "2.7.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.34", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.11.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.19", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.10.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.4", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "2.7.11.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.4", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.4.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.18", "type": "external" }, { "id": "3.1.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.24.-", "type": "external" }, { "id": "1.16.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.16.1.-", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "1.6.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.3.-", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.1.1.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.13", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0030674 protein-macromolecule adaptor activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0030054 cell junction", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0045766 positive regulation of angiogenesis;GO:0050821 protein stabilization;GO:0060996 dendritic spine development;GO:2000352 negative regulation of endothelial cell apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "B5DF62-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B5DFH3-1", "uniprot_id": [ { "id": "B5DFH3_RAT", "url": "https://www.uniprot.org/uniprot/B5DFH3", "type": "external" } ], "mass": 33962.0, "length": 313, "protein_name": "Protein sprouty homolog 1", "gene_name": "Spry1", "organism": "Rat", "refseq_name": "protein sprouty homolog 1", "refseq_ac": [ { "id": "NP_001382001", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382001", "type": "external" } ], "gene_names_uniprotkb": "Spry1", "gene_names_refseq": "Spry1", "protein_names_uniprotkb": "Protein sprouty homolog 1", "protein_names_refseq": "protein sprouty homolog 1; sprouty homolog 1, antagonist of FGF signaling", "tax_id": 10116, "disease": "", "pathway": " (rno:294981); (R-RNO-182971)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "17141539;22236546;22880013;30635790", "class_list": "", "function": "A comparison the distribution of Sprouty-1 and Sprouty-2 proteins by immunohistochemistry in developing and adult rat lung., [RefSeq, PubMed]; Expressed in the lens throughout embryogenesis, Spry1 becomes restricted to the lens epithelium, indicating that lens cell proliferation and fiber differentiation may be tightly regulated by this negative regulatory molecule., [RefSeq, PubMed]; Our findings indicate that Spry1 is an important regulator of cardiomyocyte viability during ischemia-reperfusion injury Publication Status: Online-Only, [RefSeq, PubMed]; The spatio-temporal expression of Decorin, Semaphorin6D, SPARC, Spry-1 and Tsukushi in developing prostate is described and observed similar mesenchymal expression patterns in rat and human., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, 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Or8u3", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 477; olfactory receptor Olr477; olfactory receptor gene Olr477", "tax_id": 10116, "disease": "", "pathway": " (rno:295747)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. 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Erratum:[Can J Physiol Pharmacol. 2014 Jun;92(6):519], [RefSeq, PubMed]; Lactoferrin promotes the autophagy activity during osteoblast formation via BCL2-Beclin1 signaling., [RefSeq, PubMed]; Lf supplemented in food during lactation attenuated acute and long-term cerebral LPS-induced alterations. This provides a new evidence for a promising use of Lf as a preventive neuroprotective approach in preterm encephalopathy., [RefSeq, PubMed]; The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity. Shows a preferential cleavage at -Arg-Ser-Arg-Arg-|- and -Arg-Arg-Ser-Arg-|-, and of Z-Phe-Arg-|-aminomethylcoumarin sites., [UniProtKB, UniProtKB, UniProtKB]; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, 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Publication Status: Online-Only, [RefSeq, PubMed]; Protein phosphatase involved in the inactivation of MAP kinases. Has a specificity for the MAPK11/MAPK12/MAPK13/MAPK14 subfamily. It preferably dephosphorylates p38., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, 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"D3ZC04_RAT", "url": "https://www.uniprot.org/uniprot/D3ZC04", "type": "external" } ], "mass": 100289.0, "length": 890, "protein_name": "Extended synaptotagmin-3", "gene_name": "Esyt3", "organism": "Rat", "refseq_name": "extended synaptotagmin-3", "refseq_ac": [ { "id": "NP_001416359", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001416359", "type": "external" } ], "gene_names_uniprotkb": "Esyt3", "gene_names_refseq": "Esyt3; Fam62c; RGD1561304", "protein_names_uniprotkb": "Extended synaptotagmin-3", "protein_names_refseq": "extended synaptotagmin protein 3; extended synaptotagmin-3; extended synaptotagmin-like protein 3; family with sequence similarity 62 (C2 domain containing), member C", "tax_id": 10116, "disease": "", "pathway": " (rno:363120); (R-RNO-9845576)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, 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"length": 375, "protein_name": "Structure-specific endonuclease subunit EME2", "gene_name": "Eme2", "organism": "Rat", "refseq_name": "probable crossover junction endonuclease EME2 isoform 1", "refseq_ac": [ { "id": "NP_001388876", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001388876", "type": "external" } ], "gene_names_uniprotkb": "Eme2", "gene_names_refseq": "Eme2; RGD1304924", "protein_names_uniprotkb": "Structure-specific endonuclease subunit EME2", "protein_names_refseq": "essential meiotic endonuclease 1 homolog 2; probable crossover junction endonuclease EME2 isoform 1; probable crossover junction endonuclease EME2", "tax_id": 10116, "disease": "", "pathway": " (rno:302982); (R-RNO-5693568); (R-RNO-6783310)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 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binding;GO:0004520 DNA endonuclease activity;GO:0140767 enzyme-substrate adaptor activity", "go_cellular_component": "GO:0043596 nuclear replication fork;GO:0048476 Holliday junction resolvase complex;GO:0000781 chromosome, telomeric region;GO:1905347 endodeoxyribonuclease complex;GO:0005634 nucleus", "go_biological_process": "GO:0000712 resolution of meiotic recombination intermediates;GO:0000723 telomere maintenance;GO:0006302 double-strand break repair;GO:0031573 mitotic intra-S DNA damage checkpoint signaling;GO:0031297 replication fork processing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZC60-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZCC7-1", "uniprot_id": [ { "id": "D3ZCC7_RAT", "url": "https://www.uniprot.org/uniprot/D3ZCC7", "type": "external" } ], "mass": 27741.0, "length": 246, "protein_name": "SIX homeobox 6", "gene_name": 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"reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:1990837 sequence-specific double-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0001654 eye development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZCC7-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZCD7-1", "uniprot_id": [ { "id": "D3ZCD7_RAT", "url": "https://www.uniprot.org/uniprot/D3ZCD7", "type": "external" } ], "mass": 27428.0, "length": 244, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Tp53rkb", "organism": "Rat", "refseq_name": "TP53-regulating kinase", "refseq_ac": [ { "id": "NP_001102076", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102076", "type": "external" } ], "gene_names_uniprotkb": "Tp53rkb; Tp53rk; Trp53rkb", "gene_names_refseq": "Tp53rkb; Tp53rk; Trp53rkb; 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The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TP53RK has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit OSGEP. Atypical protein kinase that phosphorylates 'Ser-15' of p53/TP53 protein and may therefore participate in its activation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, 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}, { "id": "2.7.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.34", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" }, { "id": "2.7.11.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.19", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": 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"external" } ], "gene_names_uniprotkb": "Plxnb1", "gene_names_refseq": "Plxnb1", "protein_names_uniprotkb": "Plexin-B1", "protein_names_refseq": "plexin-B1 precursor", "tax_id": 10116, "disease": "developmental disorder of mental health (Disease Ontology:DOID:0060037); obesity (Disease Ontology:DOID:9970)", "pathway": " (rno:316009); (R-RNO-416482); (R-RNO-416550); (R-RNO-416572)", "pathway_count": 4, "publication_count": 6, "publication_id_list": "15297673;16188938;26489627;28624895;35236339;38843836", "class_list": "", "function": "Increased BMSC exosomal miR-140-3p alleviates bone degradation and promotes bone restoration by targeting Plxnb1 in diabetic rats. Publication Status: Online-Only, [RefSeq, PubMed]; P190 transiently associates with plexins, and its RhoGAP activity is increased in response to semaphorin stimulation. We conclude that p190-RhoGAP is crucially involved in semaphorin signalling to the actin cytoskeleton, via interaction with plexins., [RefSeq, PubMed]; Plexin-B1 mediates Sema4D-induced repulsive axon guidance signaling by acting as a GTPase activating protein for R-Ras., [RefSeq, PubMed]; Receptor for SEMA4D. Plays a role in GABAergic synapse development. Mediates SEMA4A- and SEMA4D-dependent inhibitory synapse development. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. 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EPH-related receptor tyrosine kinase ligand 4", "protein_names_refseq": "ephrin-A4 precursor", "tax_id": 10116, "disease": "", "pathway": " (rno:310643); (R-RNO-2682334); (R-RNO-3928663); (R-RNO-3928665)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "22193443;32745487", "class_list": "", "function": "Activated ephrinA3/EphA4 forward signaling induces retinal ganglion cell apoptosis in experimental glaucoma., [RefSeq, PubMed]; Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. May play a role in the interaction between activated B-lymphocytes and dendritic cells in tonsils., [UniProtKB, UniProtKB]; Chondroitinase ABC can decrease the expression level of EphA4 and reduce the number of astrocytes after spinal cord injury., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046875 ephrin receptor binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0098552 side of membrane", "go_biological_process": "GO:0048013 ephrin receptor signaling pathway;GO:0007411 axon guidance", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZEN1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZF29-1", "uniprot_id": [ { "id": "D3ZF29_RAT", "url": "https://www.uniprot.org/uniprot/D3ZF29", "type": "external" } ], "mass": 30973.0, "length": 278, "protein_name": "Deoxyribonuclease", "gene_name": "Dnase1l2", "organism": "Rat", "refseq_name": "deoxyribonuclease-1-like 2", "refseq_ac": [ { "id": "NP_001414031", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414031", "type": "external" } ], "gene_names_uniprotkb": "Dnase1l2", "gene_names_refseq": "Dnase1l2", "protein_names_uniprotkb": "Deoxyribonuclease", "protein_names_refseq": "deoxyribonuclease I-like 2; deoxyribonuclease-1-like 2; rCG35247-like", "tax_id": 10116, "disease": "", "pathway": " (rno:681124)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Divalent cation-dependent acid DNA endonuclease involved in the breakdown of the nucleus during corneocyte formation of epidermal keratinocytes. May play an immune role by eliminating harmful DNA released into the extracellular environment by damaged epidermal cells., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0004530 deoxyribonuclease I activity;GO:0016787 hydrolase activity;GO:0004519 endonuclease activity;GO:0004536 DNA nuclease activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005634 nucleus", "go_biological_process": "GO:0001942 hair follicle development;GO:0006308 DNA catabolic process;GO:0003335 corneocyte development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZF29-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZF35-1", "uniprot_id": [ { "id": "D3ZF35_RAT", "url": "https://www.uniprot.org/uniprot/D3ZF35", "type": "external" } ], "mass": 82979.0, "length": 735, "protein_name": "Myeloid zinc finger 1", "gene_name": "Mzf1", "organism": "Rat", "refseq_name": "myeloid zinc finger 1 isoform 1", "refseq_ac": [ { "id": "NP_001101940", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101940", "type": "external" } ], "gene_names_uniprotkb": "Mzf1", "gene_names_refseq": "Mzf1; Zfp98", "protein_names_uniprotkb": "Myeloid zinc finger 1", "protein_names_refseq": "myeloid zinc finger 1 isoform 1; zinc finger protein 98", "tax_id": 10116, "disease": "", "pathway": " (rno:361508)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "25630025;31582966", "class_list": "", "function": "That MZF1 may contribute to neuropathic pain via regulation of TRPV1 expression in dorsal root ganglions Publication Status: Online-Only, [RefSeq, PubMed]; This study demonstrated that MZF1 participated in CCI-induced reductions in Kv1.2 mRNA and protein and total Kv current and the CCI-induced increase in neuronal excitability through MZF1-triggered Kv1.2 Erratum:[Pain. 2022 Feb 1;163(2):e384. doi: 10.1097/j.pain.0000000000002563. PMID: 35029603], [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042803 protein homodimerization activity;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000976 transcription cis-regulatory region binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZF35-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZF70-1", "uniprot_id": [ { "id": "D3ZF70_RAT", "url": "https://www.uniprot.org/uniprot/D3ZF70", "type": "external" } ], "mass": 114094.0, "length": 1008, "protein_name": "Family with sequence similarity 83, member B", "gene_name": "Fam83b", "organism": "Rat", "refseq_name": "protein FAM83B", "refseq_ac": [ { "id": "NP_001101639", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101639", "type": "external" } ], "gene_names_uniprotkb": "Fam83b", "gene_names_refseq": "Fam83b; RGD1311988; Sack1b", "protein_names_uniprotkb": "Family with sequence similarity 83, member B", "protein_names_refseq": "family with sequence similarity 83, member B; protein FAM83B", "tax_id": 10116, "disease": "", "pathway": " (rno:315829); (R-RNO-177929); (R-RNO-9696264); (R-RNO-9696270); (R-RNO-9696273)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0005154 epidermal growth factor receptor binding;GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding;GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0008283 cell population proliferation;GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZF70-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZFA0-1", "uniprot_id": [ { "id": "D3ZFA0_RAT", "url": "https://www.uniprot.org/uniprot/D3ZFA0", "type": "external" } ], "mass": 42025.0, "length": 375, "protein_name": "Similar to human chromosome 16 open reading frame 89", "gene_name": "C10h16orf89", "organism": "Rat", "refseq_name": "UPF0764 protein C16orf89 homolog precursor", "refseq_ac": [ { "id": "NP_001099232", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099232", "type": "external" } ], "gene_names_uniprotkb": "C10h16orf89; RGD1565166", "gene_names_refseq": "C10h16orf89; RGD1565166", "protein_names_uniprotkb": "Similar to human chromosome 16 open reading frame 89", "protein_names_refseq": "UPF0764 protein C16orf89 homolog precursor; UPF0764 protein C16orf89 homolog", "tax_id": 10116, "disease": "", "pathway": " (rno:287059)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZFA0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZFA4-1", "uniprot_id": [ { "id": "D3ZFA4_RAT", "url": "https://www.uniprot.org/uniprot/D3ZFA4", "type": "external" } ], "mass": 36357.0, "length": 320, "protein_name": "Olfactory receptor", "gene_name": "Or2a57", "organism": "Rat", "refseq_name": "olfactory receptor Olr821", "refseq_ac": [ { "id": "NP_001000842", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000842", "type": "external" } ], "gene_names_uniprotkb": "Or2a57", "gene_names_refseq": "Olr821; Or2a57", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 821; olfactory receptor Olr821; olfactory receptor gene Olr821", "tax_id": 10116, "disease": "", "pathway": " (rno:405131)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZFA4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZFM2-1", "uniprot_id": [ { "id": "D3ZFM2_RAT", "url": "https://www.uniprot.org/uniprot/D3ZFM2", "type": "external" } ], "mass": 169526.0, "length": 1546, "protein_name": "Tubby-related protein 4", "gene_name": "Tulp4", "organism": "Rat", "refseq_name": "tubby-related protein 4", "refseq_ac": [ { "id": "NP_001102607", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102607", "type": "external" } ], "gene_names_uniprotkb": "Tulp4", "gene_names_refseq": "RGD1564487; Tulp4", "protein_names_uniprotkb": "Tubby-related protein 4; Tubby superfamily protein; Tubby-like protein 4", "protein_names_refseq": "tubby like protein 4; tubby-related protein 4", "tax_id": 10116, "disease": "", "pathway": " (rno:499016); (R-RNO-8951664)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16641100", "class_list": "", "function": "May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZFM2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZFM4-1", "uniprot_id": [ { "id": "D3ZFM4_RAT", "url": "https://www.uniprot.org/uniprot/D3ZFM4", "type": "external" } ], "mass": 33304.0, "length": 293, "protein_name": "Dehydrodolichyl diphosphate synthase complex subunit NUS1", "gene_name": "Nus1", "organism": "Rat", "refseq_name": "dehydrodolichyl diphosphate synthase complex subunit NUS1", "refseq_ac": [ { "id": "NP_001157629", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157629", "type": "external" } ], "gene_names_uniprotkb": "Nus1", "gene_names_refseq": "Nus1; RGD1307879", "protein_names_uniprotkb": "Dehydrodolichyl diphosphate synthase complex subunit NUS1; 2.5.1.87; Dehydrodolichyl diphosphate synthase complex subunit nus1; Nogo-B receptor; Nuclear undecaprenyl pyrophosphate synthase 1 homolog", "protein_names_refseq": "dehydrodolichyl diphosphate synthase complex subunit NUS1; nogo-B receptor; nuclear undecaprenyl pyrophosphate synthase 1 homolog", "tax_id": 10116, "disease": "autosomal dominant intellectual developmental disorder 55 (Disease Ontology:DOID:0080227); congenital disorder of glycosylation Iaa (Disease Ontology:DOID:0080553); Parkinson's disease (Disease Ontology:DOID:14330); epilepsy (Disease Ontology:DOID:1826); congenital disorder of glycosylation (Disease Ontology:DOID:5212)", "pathway": " (rno:294400); (R-RNO-446199)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "31154456;31442237;34662809", "class_list": "", "function": "NUS1 was upregulated in IUAs tissues, and the high expression level of NUS1 was positively correlated with the severity of IUAs. NUS1 promoted cell proliferation in vitro. NUS1 overexpression on cell migration and invasion promoted the EMT process in vitro and in vivo. Publication Status: Online-Only, [RefSeq, PubMed]; Silencing Nogo-B improves the integrity of blood-retinal barrier in diabetic retinopathy via regulating Src, PI3K/Akt and ERK pathways., [RefSeq, PubMed]; The results found that capillaries and vascular smooth muscle cell content reduced, and nogo-B receptor and ICAM-1 were elevated in rats with diabetic erectile dysfunction. Publication Status: Online-Only, [RefSeq, PubMed]; With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Both subunits contribute to enzymatic activity, i.e. condensation of multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol phosphate which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER). Synthesizes long-chain polyprenols, mostly of C95 and C100 chain length. Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.5.1.87", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.87", "type": "external" }, { "id": "2.5.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.-", "type": "external" } ], "go_molecular_function": "GO:0004659 prenyltransferase activity;GO:0045547 ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity", "go_cellular_component": "GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane;GO:1904423 dehydrodolichyl diphosphate synthase complex", "go_biological_process": "GO:0001525 angiogenesis;GO:0030154 cell differentiation;GO:0032383 regulation of intracellular cholesterol transport;GO:0042632 cholesterol homeostasis;GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "D3ZFM4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZFR1-1", "uniprot_id": [ { "id": "D3ZFR1_RAT", "url": "https://www.uniprot.org/uniprot/D3ZFR1", "type": "external" } ], "mass": 43454.0, "length": 393, "protein_name": "Sulfotransferase", "gene_name": "Hs3st3a1", "organism": "Rat", "refseq_name": "heparan sulfate glucosamine 3-O-sulfotransferase 3A1", "refseq_ac": [ { "id": "NP_001165538", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001165538", "type": "external" } ], "gene_names_uniprotkb": "Hs3st3a1", "gene_names_refseq": "Hs3st3a1; Hs3st3a; RGD1561262", "protein_names_uniprotkb": "Sulfotransferase; 2.8.2.-", "protein_names_refseq": "heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1; heparan sulfate (glucosamine) 3-O-sulfotransferase 3A; heparan sulfate glucosamine 3-O-sulfotransferase 3A1", "tax_id": 10116, "disease": "", "pathway": " (rno:363618); (R-RNO-2022928)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.8.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.2.-", "type": "external" }, { "id": "2.8.2.29", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.2.29", "type": "external" } ], "go_molecular_function": "GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0006024 glycosaminoglycan biosynthetic process;GO:0001658 branching involved in ureteric bud morphogenesis;GO:0015012 heparan sulfate proteoglycan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZFR1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZG05-1", "uniprot_id": [ { "id": "D3ZG05_RAT", "url": "https://www.uniprot.org/uniprot/D3ZG05", "type": "external" } ], "mass": 14509.0, "length": 132, "protein_name": "40S ribosomal protein S12", "gene_name": "LOC120100003", "organism": "Rat", "refseq_name": "small ribosomal subunit protein eS12-like", "refseq_ac": [ { "id": "XP_063136246", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063136246", "type": "external" } ], "gene_names_uniprotkb": "LOC120100003", "gene_names_refseq": "LOC120100003", "protein_names_uniprotkb": "40S ribosomal protein S12", "protein_names_refseq": "small ribosomal subunit protein eS12-like", "tax_id": 10116, "disease": "", "pathway": " (rno:120100003)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Subunit of the 40S ribosomal complex., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:1990145 maintenance of translational fidelity;GO:0042274 ribosomal small subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZG05-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZGG8-1", "uniprot_id": [ { "id": "D3ZGG8_RAT", "url": "https://www.uniprot.org/uniprot/D3ZGG8", "type": "external" } ], "mass": 113533.0, "length": 1002, "protein_name": "Hermansky-Pudlak syndrome 3 protein homolog", "gene_name": "Hps3", "organism": "Rat", "refseq_name": "BLOC-2 complex member HPS3", "refseq_ac": [ { "id": "NP_001101134", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101134", "type": "external" } ], "gene_names_uniprotkb": "Hps3", "gene_names_refseq": "Hps3", "protein_names_uniprotkb": "Hermansky-Pudlak syndrome 3 protein homolog", "protein_names_refseq": "BLOC-2 complex member HPS3; Hermansky-Pudlak syndrome 3 homolog", "tax_id": 10116, "disease": "Hermansky-Pudlak syndrome 3 (Disease Ontology:DOID:0060541); platelet storage pool deficiency (Disease Ontology:DOID:2223); Hermansky-Pudlak syndrome (Disease Ontology:DOID:3753)", "pathway": " (rno:310288)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "29393594", "class_list": "", "function": "Involved in early stages of melanosome biogenesis and maturation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0031084 BLOC-2 complex", "go_biological_process": "GO:0043473 pigmentation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZGG8-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZGJ3-1", "uniprot_id": [ { "id": "D3ZGJ3_RAT", "url": "https://www.uniprot.org/uniprot/D3ZGJ3", "type": "external" } ], "mass": 56053.0, "length": 504, "protein_name": "Zinc finger and BTB domain containing 37", "gene_name": "Zbtb37", "organism": "Rat", "refseq_name": "zinc finger and BTB domain-containing protein 37", "refseq_ac": [ { "id": "NP_001100661", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100661", "type": "external" } ], "gene_names_uniprotkb": "Zbtb37", "gene_names_refseq": "RGD1308731; Zbtb37", "protein_names_uniprotkb": "Zinc finger and BTB domain containing 37", "protein_names_refseq": "zinc finger and BTB domain-containing protein 37", "tax_id": 10116, "disease": "", "pathway": " (rno:304918)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:1990837 sequence-specific double-stranded DNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0002682 regulation of immune system process;GO:0001817 regulation of cytokine production", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZGJ3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZGK0-1", "uniprot_id": [ { "id": "D3ZGK0_RAT", "url": "https://www.uniprot.org/uniprot/D3ZGK0", "type": "external" } ], "mass": 62595.0, "length": 567, "protein_name": "Zinc finger protein 768", "gene_name": "Zfp768", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Zfp768; LOC100361606", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger protein 768", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Binds to mammalian-wide interspersed repeat (MIRs) sequences in euchromatin and promoter regions of genes at the consensus sequence 5'-GCTGTGTG-[N20]-CCTCTCTG-3', consisting of two anchor regions connected by a linker region; the linker region probably does not contribute to the binding specificity. Required for cell homeostasis. 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Ttpal", "protein_names_uniprotkb": "Alpha tocopherol transfer protein like", "protein_names_refseq": "alpha-tocopherol transfer protein-like; tocopherol (alpha) transfer protein-like", "tax_id": 10116, "disease": "", "pathway": " (rno:296349)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:1902936 phosphatidylinositol bisphosphate binding", "go_cellular_component": "GO:0030136 clathrin-coated vesicle", "go_biological_process": "GO:0007040 lysosome organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZGM8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZGN6-1", "uniprot_id": [ { "id": "D3ZGN6_RAT", "url": "https://www.uniprot.org/uniprot/D3ZGN6", "type": "external" } ], "mass": 56721.0, "length": 506, "protein_name": "Group 3 secretory phospholipase A2", "gene_name": "Pla2g3", "organism": "Rat", "refseq_name": "group 3 secretory phospholipase A2 precursor", "refseq_ac": [ { "id": "NP_001099485", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099485", "type": "external" } ], "gene_names_uniprotkb": "Pla2g3", "gene_names_refseq": "Pla2g3", "protein_names_uniprotkb": "Group 3 secretory phospholipase A2; 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Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. 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Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation., [UniProtKB, UniProtKB]; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. 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(R-RNO-6798695)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "16213650;28714326", "class_list": "", "function": "Identification and functional analysis of the human Rap2C ortholog., [RefSeq, PubMed]; Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form., [UniProtKB, UniProtKB]; Study found that SCII upregulated the expression of miR-204 and downregulated the expression of RAP2C; that hypoxia increased the expression of miR-204 and decreased the expression of RAP2C, and overexpression of RAP2C attenuates the effect of hypoxia on apoptosis rate; and miR-204 could directly bind to RAP2C, and could regulate the expression of RAP2C., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.1", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" } ], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0019003 GDP binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005923 bicellular tight junction;GO:0016020 membrane", "go_biological_process": "GO:0032486 Rap protein signal transduction;GO:0030336 negative regulation of cell migration;GO:0090557 establishment of endothelial intestinal barrier;GO:0031954 positive regulation of protein autophosphorylation;GO:0061097 regulation of protein tyrosine kinase activity", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZK56-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZKF6-1", "uniprot_id": [ { "id": "D3ZKF6_RAT", "url": "https://www.uniprot.org/uniprot/D3ZKF6", "type": "external" } ], "mass": 87770.0, "length": 750, "protein_name": "EF-hand domain-containing family member C2", "gene_name": "Efhc2", "organism": "Rat", "refseq_name": "EF-hand domain-containing family member C2", "refseq_ac": [ { "id": "NP_001100422", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100422", "type": "external" } ], "gene_names_uniprotkb": "Efhc2", "gene_names_refseq": "Efhc2; RGD1563388", "protein_names_uniprotkb": "EF-hand domain-containing family member C2", "protein_names_refseq": "EF-hand domain (C-terminal) containing 2; EF-hand domain-containing family member C2", "tax_id": 10116, "disease": "", "pathway": " (rno:302507)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0036126 sperm flagellum;GO:0036064 ciliary basal body;GO:0005879 axonemal microtubule;GO:0160111 axonemal A tubule inner sheath", "go_biological_process": "GO:0048814 regulation of dendrite morphogenesis;GO:0030317 flagellated sperm motility;GO:1990830 cellular response to leukemia inhibitory factor", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZKF6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZKN1-1", "uniprot_id": [ { "id": "D3ZKN1_RAT", "url": "https://www.uniprot.org/uniprot/D3ZKN1", "type": "external" } ], "mass": 39894.0, "length": 371, "protein_name": "BPI fold containing family A, member 6", "gene_name": "Bpifa6", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Bpifa6", "gene_names_refseq": "", "protein_names_uniprotkb": "BPI fold containing family A, member 6", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008289 lipid binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZKN1-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZKR4-1", "uniprot_id": [ { "id": "D3ZKR4_RAT", "url": "https://www.uniprot.org/uniprot/D3ZKR4", "type": "external" } ], "mass": 35261.0, "length": 315, "protein_name": "Olfactory receptor family 2 subfamily D member 2", "gene_name": "Or2d2b", "organism": "Rat", "refseq_name": "olfactory receptor Olr233", "refseq_ac": [ { "id": "NP_001000207", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000207", "type": "external" } ], "gene_names_uniprotkb": "Or2d2b; Or2d2", "gene_names_refseq": "Olr233; Or2d2; ratchr1-164507524-164506577_ORF", "protein_names_uniprotkb": "Olfactory receptor family 2 subfamily D member 2", "protein_names_refseq": "olfactory receptor 233; olfactory receptor Olr233; olfactory receptor gene Olr233", "tax_id": 10116, "disease": "", "pathway": " (rno:293377); (rno:405921)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZKR4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZLD7-1", "uniprot_id": [ { "id": "D3ZLD7_RAT", "url": "https://www.uniprot.org/uniprot/D3ZLD7", "type": "external" } ], "mass": 129906.0, "length": 1150, "protein_name": "Protein phosphatase 2, regulatory subunit B'', alpha", "gene_name": "Ppp2r3a", "organism": "Rat", "refseq_name": "serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha", "refseq_ac": [ { "id": "NP_001012202", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012202", "type": "external" } ], "gene_names_uniprotkb": "Ppp2r3a", "gene_names_refseq": "Ppp2r3a", "protein_names_uniprotkb": "Protein phosphatase 2, regulatory subunit B'', alpha", "protein_names_refseq": "DNA for thyroid hormone receptor binding site (258bp); protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha", "tax_id": 10116, "disease": "", "pathway": " (rno:363122)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "34635097;34982454", "class_list": "", "function": "The B regulatory subunit might modulate substrate selectivity and catalytic activity, and might also direct the localization of the catalytic enzyme to a particular subcellular compartment., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; The potential mechanism of PPP2R3A in myocardial cells and its interacting proteins., [RefSeq, PubMed]; Zinc-mediated activation of CREB pathway in proliferation of pulmonary artery smooth muscle cells in pulmonary hypertension. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0019888 protein phosphatase regulator activity;GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0000159 protein phosphatase type 2A complex", "go_biological_process": "GO:0007525 somatic muscle development;GO:0090249 regulation of cell migration involved in somitogenic axis elongation;GO:0001756 somitogenesis;GO:0060828 regulation of canonical Wnt signaling pathway;GO:0090090 negative regulation of canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZLD7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZLM5-1", "uniprot_id": [ { "id": "D3ZLM5_RAT", "url": "https://www.uniprot.org/uniprot/D3ZLM5", "type": "external" } ], "mass": 78562.0, "length": 725, "protein_name": "NHL repeat-containing protein 2", "gene_name": "Nhlrc2", "organism": "Rat", "refseq_name": "NHL repeat-containing protein 2", "refseq_ac": [ { "id": "NP_001100914", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100914", "type": "external" } ], "gene_names_uniprotkb": "Nhlrc2", "gene_names_refseq": "Nhlrc2", "protein_names_uniprotkb": "NHL repeat-containing protein 2", "protein_names_refseq": "NHL repeat-containing protein 2", "tax_id": 10116, "disease": "", "pathway": " (rno:307986); (R-RNO-114608)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for normal embryonic development., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZLM5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZLM6-1", "uniprot_id": [ { "id": "D3ZLM6_RAT", "url": "https://www.uniprot.org/uniprot/D3ZLM6", "type": "external" } ], "mass": 59219.0, "length": 536, "protein_name": "dolichol kinase", "gene_name": "Dolk", "organism": "Rat", "refseq_name": "dolichol kinase", "refseq_ac": [ { "id": "NP_001101296", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101296", "type": "external" } ], "gene_names_uniprotkb": "Dolk", "gene_names_refseq": "Dolk; Tmem15", "protein_names_uniprotkb": "dolichol kinase; 2.7.1.108", "protein_names_refseq": "dolichol kinase; transmembrane protein 15", "tax_id": 10116, "disease": "congenital disorder of glycosylation type I (Disease Ontology:DOID:0050570); congenital disorder of glycosylation Im (Disease Ontology:DOID:0080565)", "pathway": " (rno:311847); (R-RNO-446199)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.108", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.108", "type": "external" } ], "go_molecular_function": "GO:0004168 dolichol kinase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0043048 dolichyl monophosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZLM6-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZLV0-1", "uniprot_id": [ { "id": "D3ZLV0_RAT", "url": "https://www.uniprot.org/uniprot/D3ZLV0", "type": "external" } ], "mass": 35939.0, "length": 327, "protein_name": "Olfactory receptor", "gene_name": "Or5c1", "organism": "Rat", "refseq_name": "olfactory receptor Olr434", "refseq_ac": [ { "id": "NP_001000397", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000397", "type": "external" } ], "gene_names_uniprotkb": "Or5c1; Olr434", "gene_names_refseq": "Olr434; Or5c1", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 434; olfactory receptor Olr434; olfactory receptor gene Olr434", "tax_id": 10116, "disease": "", "pathway": " (rno:296694)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZLV0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZM03-1", "uniprot_id": [ { "id": "D3ZM03_RAT", "url": "https://www.uniprot.org/uniprot/D3ZM03", "type": "external" } ], "mass": 11381.0, "length": 101, "protein_name": "Vacuolar ATPase assembly factor VMA21", "gene_name": "Vma21", "organism": "Rat", "refseq_name": "vacuolar ATPase assembly integral membrane protein VMA21 isoform 2", "refseq_ac": [ { "id": "NP_001389190", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001389190", "type": "external" } ], "gene_names_uniprotkb": "Vma21", "gene_names_refseq": "RGD1566155; Vma21", "protein_names_uniprotkb": "Vacuolar ATPase assembly factor VMA21", "protein_names_refseq": "VMA21 vacuolar H+-ATPase homolog; VMA21, vacuolar ATPase assembly factor; vacuolar ATPase assembly integral membrane protein VMA21 isoform 2; vacuolar ATPase assembly integral membrane protein VMA21-like; vacuolar ATPase assembly integral membrane protein VMA21", "tax_id": 10116, "disease": "X-linked myopathy with excessive autophagy (Disease Ontology:DOID:0050760); follicular lymphoma (Disease Ontology:DOID:0050873)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0012507 ER to Golgi transport vesicle membrane;GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005764 lysosome", "go_biological_process": "GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly;GO:0007042 lysosomal lumen acidification", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZM03-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZM05-1", "uniprot_id": [ { "id": "D3ZM05_RAT", "url": "https://www.uniprot.org/uniprot/D3ZM05", "type": "external" } ], "mass": 87209.0, "length": 768, "protein_name": "Tetratricopeptide repeat domain 14", "gene_name": "Ttc14", "organism": "Rat", "refseq_name": "tetratricopeptide 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"uniprot_canonical_ac": "D3ZM19-1", "uniprot_id": [ { "id": "D3ZM19_RAT", "url": "https://www.uniprot.org/uniprot/D3ZM19", "type": "external" } ], "mass": 45615.0, "length": 420, "protein_name": "Ecotropic viral integration site 2B", "gene_name": "Evi2b", "organism": "Rat", "refseq_name": "protein EVI2B precursor", "refseq_ac": [ { "id": "NP_001258411", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258411", "type": "external" } ], "gene_names_uniprotkb": "Evi2b; LOC100910940", "gene_names_refseq": "Evi2b", "protein_names_uniprotkb": "Ecotropic viral integration site 2B", "protein_names_refseq": "protein EVI2B precursor; protein EVI2B-like", "tax_id": 10116, "disease": "", "pathway": " (rno:100910940)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "22673903;29393594", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, 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"go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0030854 positive regulation of granulocyte differentiation;GO:2000035 regulation of stem cell division;GO:0045660 positive regulation of neutrophil differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZM19-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZM39-1", "uniprot_id": [ { "id": "D3ZM39_RAT", "url": "https://www.uniprot.org/uniprot/D3ZM39", "type": "external" } ], "mass": 113911.0, "length": 1060, "protein_name": "Desmoglein 1", "gene_name": "Dsg1", "organism": "Rat", "refseq_name": "desmoglein-1 precursor", "refseq_ac": [ { "id": "NP_001419356", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001419356", "type": "external" } ], "gene_names_uniprotkb": "Dsg1", "gene_names_refseq": "Dsg1b; Dsg1c; Dsg1", "protein_names_uniprotkb": "Desmoglein 1", "protein_names_refseq": "desmoglein 1 beta; desmoglein 1 gamma; desmoglein-1 precursor", "tax_id": 10116, "disease": "keratosis palmoplantaris striata 1 (Disease Ontology:DOID:0081108)", "pathway": " (R-RNO-351906); (R-RNO-6798695); (R-RNO-6805567); (R-RNO-6809371); (R-RNO-9696264); (R-RNO-9696270)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion., [UniProtKB, UniProtKB]; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, 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"D3ZM64-1", "uniprot_id": [ { "id": "D3ZM64_RAT", "url": "https://www.uniprot.org/uniprot/D3ZM64", "type": "external" } ], "mass": 93818.0, "length": 832, "protein_name": "Protein Jade-1", "gene_name": "Jade1", "organism": "Rat", "refseq_name": "protein Jade-1", "refseq_ac": [ { "id": "NP_001401981", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001401981", "type": "external" } ], "gene_names_uniprotkb": "Jade1; Phf17", "gene_names_refseq": "Jade1; Phf17", "protein_names_uniprotkb": "Protein Jade-1; Jade family PHD finger protein 1; PHD finger protein 17", "protein_names_refseq": "PHD finger protein 17; protein Jade-1", "tax_id": 10116, "disease": "", "pathway": " (rno:310352); (R-RNO-3214847)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator 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"NP_001178764", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178764", "type": "external" } ], "gene_names_uniprotkb": "Cplx4", "gene_names_refseq": "Cplx4", "protein_names_uniprotkb": "Complexin 4", "protein_names_refseq": "complexin-4", "tax_id": 10116, "disease": "depressive disorder (Disease Ontology:DOID:1596)", "pathway": " (rno:361342)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019905 syntaxin binding;GO:0000149 SNARE binding", "go_cellular_component": "GO:0043195 terminal bouton;GO:0045202 synapse;GO:0031201 SNARE complex", "go_biological_process": "GO:0046928 regulation of neurotransmitter secretion;GO:0050804 modulation of chemical synaptic transmission;GO:0031630 regulation of synaptic vesicle fusion to presynaptic active zone membrane;GO:0016079 synaptic vesicle exocytosis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZM85-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZM88-1", "uniprot_id": [ { "id": "D3ZM88_RAT", "url": "https://www.uniprot.org/uniprot/D3ZM88", "type": "external" } ], "mass": 34592.0, "length": 312, "protein_name": "Olfactory receptor", "gene_name": "Or7g16", "organism": "Rat", "refseq_name": "olfactory receptor Olr1122", "refseq_ac": [ { "id": "NP_001000882", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000882", "type": "external" } ], "gene_names_uniprotkb": "Or7g16", "gene_names_refseq": "Olr1122; Or7g16", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1122; olfactory receptor Olr1122; olfactory receptor gene Olr1122", "tax_id": 10116, "disease": "", "pathway": " (rno:405181)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]; Possible taste receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3ZZK4", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZM88-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZMB1-1", "uniprot_id": [ { "id": "D3ZMB1_RAT", "url": "https://www.uniprot.org/uniprot/D3ZMB1", "type": "external" } ], "mass": 25102.0, "length": 221, "protein_name": "Tumor rejection antigen P1A", "gene_name": "Trap1a", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Trap1a", "gene_names_refseq": "", "protein_names_uniprotkb": "Tumor rejection antigen P1A", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:680619)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZMB1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true } ]