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        "function": "Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10. Binds to polypyrimidine-rich controlling element (PCE) of CFTR and promotes exon skipping of CFTR exon 9, thereby antagonizing TIA1 and its role in exon inclusion of CFTR exon 9. Plays a role in the splicing of pyruvate kinase PKM by binding repressively to a polypyrimidine tract flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes Fas exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0003723 RNA binding;GO:0003729 mRNA binding",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006397 mRNA processing;GO:0045595 regulation of cell differentiation;GO:0043249 erythrocyte maturation;GO:0008380 RNA splicing;GO:0043484 regulation of RNA splicing",
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        "hit_score": 0.2,
        "record_id": "A0A288CFU5-1",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A481C860-1",
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            {
                "id": "A0A481C860_PIG",
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            }
        ],
        "mass": 49678.0,
        "length": 446,
        "protein_name": "RING-type E3 ubiquitin transferase",
        "gene_name": "PJA1",
        "organism": "Pig",
        "refseq_name": "E3 ubiquitin-protein ligase Praja-1 isoform X3",
        "refseq_ac": [
            {
                "id": "XP_005673760",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005673760",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "PJA1",
        "gene_names_refseq": "PJA1",
        "protein_names_uniprotkb": "RING-type E3 ubiquitin transferase; 2.3.2.27",
        "protein_names_refseq": "E3 ubiquitin-protein ligase Praja-1 isoform X3",
        "tax_id": 9823,
        "disease": "",
        "pathway": " (ssc:100518407);  (R-SSC-983168)",
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        "secondary_ac_list": "A0A287B4A5",
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        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity",
        "go_cellular_component": "GO:0005737 cytoplasm",
        "go_biological_process": "GO:0016567 protein ubiquitination",
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        "hit_score": 0.2,
        "record_id": "A0A481C860-1",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A4X1SFW8-1",
        "uniprot_id": [
            {
                "id": "A0A4X1SFW8_PIG",
                "url": "https://www.uniprot.org/uniprot/A0A4X1SFW8",
                "type": "external"
            }
        ],
        "mass": 24798.0,
        "length": 220,
        "protein_name": "Ras-related protein Rab-28",
        "gene_name": "RAB28",
        "organism": "Pig",
        "refseq_name": "ras-related protein Rab-28 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_020955930",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955930",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "RAB28",
        "gene_names_refseq": "RAB28; RB28",
        "protein_names_uniprotkb": "Ras-related protein Rab-28; 3.6.5.2",
        "protein_names_refseq": "ras-related protein Rab-28 isoform X1",
        "tax_id": 9823,
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        "function": "The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB28 is required for shedding and phagocytosis of cone cell outer segments (OS) discs in the retina. Also participates in nuclear factor kappa-B p65/RELA nuclear transport in endothelial cells., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0019003 GDP binding;GO:0003925 G protein activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005886 plasma membrane;GO:0012505 endomembrane system;GO:0030670 phagocytic vesicle membrane;GO:0005770 late endosome",
        "go_biological_process": "GO:0006886 intracellular protein transport;GO:0015031 protein transport",
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    },
    {
        "uniprot_canonical_ac": "A0A287BSR3-1",
        "uniprot_id": [
            {
                "id": "A0A287BSR3_PIG",
                "url": "https://www.uniprot.org/uniprot/A0A287BSR3",
                "type": "external"
            }
        ],
        "mass": 40429.0,
        "length": 364,
        "protein_name": "Solute carrier family 35 member C2",
        "gene_name": "SLC35C2",
        "organism": "Pig",
        "refseq_name": "solute carrier family 35 member H1",
        "refseq_ac": [
            {
                "id": "NP_001172088",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001172088",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "SLC35C2",
        "gene_names_refseq": "SLC35C2",
        "protein_names_uniprotkb": "Solute carrier family 35 member C2",
        "protein_names_refseq": "solute carrier family 35 member H1",
        "tax_id": 9823,
        "disease": "",
        "pathway": " (ssc:100152375)",
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        "go_molecular_function": "GO:0015297 antiporter activity",
        "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0016020 membrane;GO:0005801 cis-Golgi network;GO:0005793 endoplasmic reticulum-Golgi intermediate compartment",
        "go_biological_process": "GO:0015786 UDP-glucose transmembrane transport",
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        "hit_score": 0.2,
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    },
    {
        "uniprot_canonical_ac": "A0A287BRP1-1",
        "uniprot_id": [
            {
                "id": "A0A287BRP1_PIG",
                "url": "https://www.uniprot.org/uniprot/A0A287BRP1",
                "type": "external"
            }
        ],
        "mass": 54572.0,
        "length": 506,
        "protein_name": "Na(+)/H(+) exchange regulatory cofactor NHE-RF4",
        "gene_name": "NHERF4",
        "organism": "Pig",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "NHERF4",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Na(+)/H(+) exchange regulatory cofactor NHE-RF4; Natrium-phosphate cotransporter IIa C-terminal-associated protein 2; PDZ domain-containing protein 2; PDZ domain-containing protein 3; Sodium-hydrogen exchanger regulatory factor 4",
        "protein_names_refseq": "",
        "tax_id": 9823,
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        "class_list": "",
        "function": "Acts as a regulatory protein that associates with GUCY2C and negatively modulates its heat-stable enterotoxin-mediated activation. Stimulates SLC9A3 activity in the presence of elevated calcium ions., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0043495 protein-membrane adaptor activity;GO:1990381 ubiquitin-specific protease binding;GO:0030251 guanylate cyclase inhibitor activity",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005903 brush border;GO:0016324 apical plasma membrane;GO:0043296 apical junction complex;GO:0005886 plasma membrane",
        "go_biological_process": "GO:0072659 protein localization to plasma membrane",
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        "hit_score": 0.2,
        "record_id": "A0A287BRP1-1",
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        "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000",
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    },
    {
        "uniprot_canonical_ac": "A0A480TMJ2-1",
        "uniprot_id": [
            {
                "id": "A0A480TMJ2_PIG",
                "url": "https://www.uniprot.org/uniprot/A0A480TMJ2",
                "type": "external"
            }
        ],
        "mass": 60005.0,
        "length": 522,
        "protein_name": "MSL complex subunit 3",
        "gene_name": "MSL3",
        "organism": "Pig",
        "refseq_name": "MSL complex subunit 3 isoform 1",
        "refseq_ac": [
            {
                "id": "NP_001231010",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231010",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "MSL3",
        "gene_names_refseq": "MSL3",
        "protein_names_uniprotkb": "MSL complex subunit 3; Male-specific lethal 3 homolog; Male-specific lethal-3 homolog 1; Male-specific lethal-3 protein-like 1",
        "protein_names_refseq": "MSL complex subunit 3 isoform 1; male-specific lethal 3 homolog",
        "tax_id": 9823,
        "disease": "",
        "pathway": " (ssc:100526025);  (R-SSC-3214847)",
        "pathway_count": 2,
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        "class_list": "",
        "function": "Non-catalytic component of the MSL histone acetyltransferase complex, a multiprotein complex that mediates the majority of histone H4 acetylation at 'Lys-16' (H4K16ac), an epigenetic mark that prevents chromatin compaction. The MSL complex is required for chromosome stability and genome integrity by maintaining homeostatic levels of H4K16ac. The MSL complex is also involved in gene dosage by promoting up-regulation of genes expressed by the X chromosome. X up-regulation is required to compensate for autosomal biallelic expression. The MSL complex also participates in gene dosage compensation by promoting expression of Tsix non-coding RNA. Acts as a histone reader that specifically recognizes and binds histone H4 monomethylated at 'Lys-20' (H4K20Me1) in a DNA-dependent manner and is proposed to be involved in chromosomal targeting of the MSL complex. May play a role X inactivation in females., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "secondary_ac_list": "F1SG12",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003677 DNA binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0035267 NuA4 histone acetyltransferase complex;GO:0072487 MSL complex",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription;GO:0006325 chromatin organization;GO:0006355 regulation of DNA-templated transcription",
        "synthesized_glycan_count": 0,
        "hit_score": 0.2,
        "record_id": "A0A480TMJ2-1",
        "record_type": "protein",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A480SNH9-1",
        "uniprot_id": [
            {
                "id": "A0A480SNH9_PIG",
                "url": "https://www.uniprot.org/uniprot/A0A480SNH9",
                "type": "external"
            }
        ],
        "mass": 37424.0,
        "length": 340,
        "protein_name": "CD2 antigen cytoplasmic tail-binding protein 2",
        "gene_name": "CD2BP2",
        "organism": "Pig",
        "refseq_name": "CD2 antigen cytoplasmic tail-binding protein 2",
        "refseq_ac": [
            {
                "id": "XP_003354584",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003354584",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "CD2BP2",
        "gene_names_refseq": "CD2BP2",
        "protein_names_uniprotkb": "CD2 antigen cytoplasmic tail-binding protein 2",
        "protein_names_refseq": "CD2 antigen cytoplasmic tail-binding protein 2",
        "tax_id": 9823,
        "disease": "",
        "pathway": " (ssc:100621208)",
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        "class_list": "",
        "function": "Involved in pre-mRNA splicing as component of the U5 snRNP complex that is involved in spliceosome assembly., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 2,
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        ],
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        ],
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            }
        ],
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        "protein_name": "U5 small nuclear ribonucleoprotein 40 kDa protein",
        "gene_name": "SNRNP40",
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        "refseq_name": "U5 small nuclear ribonucleoprotein 40 kDa protein",
        "refseq_ac": [
            {
                "id": "XP_003356314",
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            }
        ],
        "gene_names_uniprotkb": "SNRNP40",
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        "protein_names_uniprotkb": "U5 small nuclear ribonucleoprotein 40 kDa protein; WD repeat-containing protein 57",
        "protein_names_refseq": "U5 small nuclear ribonucleoprotein 40 kDa protein",
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        "function": "Required for pre-mRNA splicing as component of the activated spliceosome. Component of the U5 small nuclear ribonucleoprotein (snRNP) complex and the U4/U6-U5 tri-snRNP complex, building blocks of the spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs., [UniProtKB, UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:0016607 nuclear speck;GO:0071007 U2-type catalytic step 2 spliceosome;GO:0005682 U5 snRNP;GO:0005681 spliceosomal complex",
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    },
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        ],
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            {
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        "go_molecular_function": "GO:0016279 protein-lysine N-methyltransferase activity;GO:0008168 methyltransferase activity",
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        "go_biological_process": "GO:1904736 negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase;GO:0032259 methylation",
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    },
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        ],
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            {
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            }
        ],
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        "go_molecular_function": "GO:0030331 nuclear estrogen receptor binding",
        "go_cellular_component": "GO:0044666 MLL3/4 complex",
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        ],
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        "protein_name": "Zinc finger protein 70",
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        ],
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        "protein_name": "Heat shock transcription factor 2 binding protein",
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            {
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            }
        ],
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        "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005694 chromosome",
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        ],
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        "protein_name": "Dihydropyrimidinase-related protein 4",
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            {
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        ],
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        "protein_names_uniprotkb": "Dihydropyrimidinase-related protein 4; Collapsin response mediator protein 3; UNC33-like phosphoprotein 4",
        "protein_names_refseq": "dihydropyrimidinase-related protein 4",
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        "function": "Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides;GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds",
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        ],
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        "protein_name": "Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7",
        "gene_name": "JMJD7",
        "organism": "Pig",
        "refseq_name": "bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7",
        "refseq_ac": [
            {
                "id": "NP_001191173",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191173",
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        ],
        "gene_names_uniprotkb": "JMJD7",
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        "protein_names_uniprotkb": "Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7; 1.14.11.63; JmjC domain-containing protein 7; Jumonji domain-containing protein 7",
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        "function": "Bifunctional enzyme that acts both as an endopeptidase and 2-oxoglutarate-dependent monooxygenase. Endopeptidase that cleaves histones N-terminal tails at the carboxyl side of methylated arginine or lysine residues, to generate 'tailless nucleosomes', which may trigger transcription elongation. Preferentially recognizes and cleaves monomethylated and dimethylated arginine residues of histones H2, H3 and H4. After initial cleavage, continues to digest histones tails via its aminopeptidase activity. Additionally, may play a role in protein biosynthesis by modifying the translation machinery. Acts as a Fe(2+) and 2-oxoglutarate-dependent monooxygenase, catalyzing (S)-stereospecific hydroxylation at C-3 of 'Lys-22' of DRG1 and 'Lys-21' of DRG2 translation factors (TRAFAC), promoting their interaction with ribonucleic acids (RNA)., [UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005925 focal adhesion;GO:0005634 nucleus",
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    },
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        ],
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        "publication_id_list": "29550768;30135578;30135580;32541898;32543654;33446560;33795473;33902107;33958484;34021257;34265249;34526721;34530439;34762484;35476980;35858621;36201575;36424526;36869814;37148879;37369200;37932450;38127763;38401543;38570683;38604172;38816438;39547223;39547229;39666822;39762629;40043114;40835814;41162378",
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        "function": "Isoform 2 may participate in the regulation of nucleoplasmic coilin protein interactions in neuronal and transformed cells., [UniProtKB, UniProtKB]; Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation., [UniProtKB, UniProtKB, UniProtKB]",
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    },
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        "protein_names_uniprotkb": "Pro-neuregulin-3, membrane-bound isoform",
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        "pathway": " (R-SSC-1227986);  (R-SSC-1236394);  (R-SSC-1250196);  (R-SSC-1250342);  (R-SSC-1250347);  (R-SSC-1257604);  (R-SSC-1963640);  (R-SSC-1963642);  (R-SSC-5673001);  (R-SSC-6785631);  (R-SSC-6811558);  (R-SSC-8847993);  (R-SSC-8863795)",
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        "go_biological_process": "GO:0007416 synapse assembly;GO:0050804 modulation of chemical synaptic transmission;GO:0038138 ERBB4-ERBB4 signaling pathway;GO:0007399 nervous system development;GO:0035556 intracellular signal transduction",
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        "go_molecular_function": "GO:0033677 DNA/RNA helicase activity;GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0003725 double-stranded RNA binding",
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        ],
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        "protein_name": "Hypoxia up-regulated protein 1",
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            {
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    },
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            }
        ],
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            {
                "id": "NP_001254761",
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            }
        ],
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        ],
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        ],
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        ],
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        "protein_name": "Laminin subunit alpha-3",
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            {
                "id": "XP_003482090",
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        ],
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        "protein_names_refseq": "laminin subunit alpha 3 precursor; laminin, alpha 3",
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        "pathway": " (ssc:100511642);  (R-SSC-1474228);  (R-SSC-2022090);  (R-SSC-3000157);  (R-SSC-446107);  (R-SSC-9913351)",
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        "function": "Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components., [UniProtKB, UniProtKB, UniProtKB]; Laminin-5 is thought to be involved in (1) cell adhesion via integrin alpha-3/beta-1 in focal adhesion and integrin alpha-6/beta-4 in hemidesmosomes, (2) signal transduction via tyrosine phosphorylation of pp125-FAK and p80, (3) differentiation of keratinocytes., [UniProtKB, UniProtKB, UniProtKB]",
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        ],
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        "go_cellular_component": "GO:0000139 Golgi membrane;GO:0017119 Golgi transport complex",
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        ],
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        "protein_name": "Vesicle transport protein",
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            {
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        ],
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        "gene_names_refseq": "SFT2D1",
        "protein_names_uniprotkb": "Vesicle transport protein",
        "protein_names_refseq": "vesicle transport protein SFT2A",
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        "function": "May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "gene_names_uniprotkb": "NUDT17",
        "gene_names_refseq": "NUDT17",
        "protein_names_uniprotkb": "m7GpppN-mRNA hydrolase NUDT17; 3.6.1.62; Nucleoside diphosphate-linked moiety X motif 17",
        "protein_names_refseq": "nucleoside diphosphate-linked moiety X motif 17 isoform X1",
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        "function": "Acts as a decapping enzyme capable of hydrolyzing monomethylated capped RNAs (in vitro). Hydrolyzes monomethylated capped RNA after alpha and beta phosphates to form N(7)-methyl-GDP. Shows low activity towards unmethylated capped RNA., [UniProtKB, UniProtKB, UniProtKB]",
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        ],
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        "function": "Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate to L-proline using NAD(P)H. At physiologic concentrations, has higher specific activity in the presence of NADH. Involved in cellular response to oxidative stress. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0000794 condensed nuclear chromosome;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005813 centrosome",
        "go_biological_process": "GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex;GO:0007018 microtubule-based movement;GO:0044782 cilium organization",
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        "protein_name": "Neutral ceramidase",
        "gene_name": "ASAH2",
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        "refseq_name": "neutral ceramidase",
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            {
                "id": "XP_005671307",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005671307",
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            }
        ],
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        "go_biological_process": "GO:0046513 ceramide biosynthetic process;GO:0046512 sphingosine biosynthetic process;GO:0046514 ceramide catabolic process;GO:0044241 lipid digestion;GO:0042759 long-chain fatty acid biosynthetic process",
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                "id": "XP_003130335",
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        "function": "Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate (TPP) utilizing UTP and therefore links the biosynthesis of TPP to pyrimidines metabolism. By producing thiamine pyrophosphate, a cofactor of the mitochondrial pyruvate dehydrogenase indirectly regulates pyruvate oxidation and lipogenesis. Although it can also catalyze thiamine phosphorylation using ATP and CTP in vitro, it does so with significantly lower efficiency and without physiological relevance evidence., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "protein_name": "Nectin-1",
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        "refseq_name": "nectin-1 precursor",
        "refseq_ac": [
            {
                "id": "NP_001001262",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001262",
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            }
        ],
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        "protein_names_refseq": "herpes virus entry mediator C; herpesvirus entry mediator C; nectin-1 precursor; nectin-1; poliovirus receptor-related 1 (herpesvirus entry mediator C); poliovirus receptor-related protein 1",
        "tax_id": 9823,
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        "pathway": " (ssc:397247);  (R-SSC-418990);  (R-SSC-420597)",
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        "function": "A monoclonal antibody neutralizes pesudorabies virus by blocking gD binding to the receptor nectin-1., [RefSeq, PubMed]; Contribution of the second and third Ig-like domains of nectin-1 was analysed by generating transgenic mice expressing the entire ectodomain of nectin-1 fused to the porcine Fc portion., [RefSeq, PubMed]; Pseudorabies virus infects host cells via both human and swine nectin-1. Publication Status: Online-Only, [RefSeq, PubMed]; Results demonstrate that a soluble form of the first domain of porcine nectin-1 is able to exert a significant antiviral effect against pseudorabies virus infection., [RefSeq, PubMed]",
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        "go_cellular_component": "GO:0048787 presynaptic active zone membrane;GO:0005886 plasma membrane;GO:0005912 adherens junction;GO:0044291 cell-cell contact zone;GO:0043296 apical junction complex",
        "go_biological_process": "GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0090103 cochlea morphogenesis;GO:1902414 protein localization to cell junction;GO:0007155 cell adhesion",
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        ],
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        "protein_name": "Oxysterol-binding protein",
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        "refseq_name": "oxysterol-binding protein-related protein 1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_013854717",
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        "protein_names_refseq": "oxysterol-binding protein-related protein 1 isoform X1",
        "tax_id": 9823,
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        "pathway": " (R-SSC-192105);  (R-SSC-2132295)",
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        "function": "Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate. Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A. Binds 25-hydroxycholesterol and cholesterol., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0008289 lipid binding;GO:0015485 cholesterol binding;GO:0032935 sterol sensor activity",
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        "go_biological_process": "GO:0006869 lipid transport;GO:0042632 cholesterol homeostasis;GO:0090120 lysosome to ER cholesterol transport",
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        ],
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        "length": 535,
        "protein_name": "Heat shock transcription factor 2",
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        "refseq_name": "heat shock factor protein 2 isoform X1",
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            {
                "id": "XP_005659284",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005659284",
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            }
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        "protein_names_uniprotkb": "Heat shock transcription factor 2",
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        "tax_id": 9823,
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        "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0043565 sequence-specific DNA binding;GO:0042802 identical protein binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm",
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        ],
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        "protein_name": "Deoxyhypusine hydroxylase",
        "gene_name": "DOHH",
        "organism": "Pig",
        "refseq_name": "deoxyhypusine hydroxylase",
        "refseq_ac": [
            {
                "id": "XP_003123090",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123090",
                "type": "external"
            }
        ],
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        "protein_names_uniprotkb": "Deoxyhypusine hydroxylase; 1.14.99.29; DOHH; Deoxyhypusine dioxygenase; Deoxyhypusine monooxygenase",
        "protein_names_refseq": "deoxyhypusine hydroxylase",
        "tax_id": 9823,
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        "function": "Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF-5A. This is the second step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor., [UniProtKB, HAMAP, UniProtKB, UniProtKB]",
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            {
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            {
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        ],
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        "pathway": " (R-SSC-1222556);  (R-SSC-77387);  (R-SSC-917977);  (R-SSC-9639288);  (R-SSC-983712)",
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        "go_cellular_component": "GO:0005634 nucleus",
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            {
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            }
        ],
        "gene_names_uniprotkb": "SCAMP4",
        "gene_names_refseq": "SCAMP4",
        "protein_names_uniprotkb": "Secretory carrier-associated membrane protein; Secretory carrier membrane protein",
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        "publication_id_list": "32543654",
        "class_list": "",
        "function": "Probably involved in membrane protein trafficking., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:0016020 membrane;GO:0032588 trans-Golgi network membrane;GO:0055038 recycling endosome membrane",
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            }
        ],
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            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134325",
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        "protein_names_refseq": "D-tyrosyl-tRNA(Tyr) deacylase 1",
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        "protein_names_uniprotkb": "OXA1L mitochondrial inner membrane protein",
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        "go_biological_process": "GO:0051262 protein tetramerization;GO:0032981 mitochondrial respiratory chain complex I assembly;GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly;GO:0009060 aerobic respiration;GO:0032979 protein insertion into mitochondrial inner membrane from matrix",
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        "protein_name": "Glia maturation factor",
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            {
                "id": "XP_013845962",
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        ],
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        "protein_names_refseq": "glia maturation factor gamma isoform X2",
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        "go_molecular_function": "GO:0003779 actin binding;GO:0008083 growth factor activity;GO:0071933 Arp2/3 complex binding",
        "go_cellular_component": "GO:0030864 cortical actin cytoskeleton;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0071944 cell periphery",
        "go_biological_process": "GO:0071846 actin filament debranching;GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation",
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    {
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        ],
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        "refseq_ac": [],
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        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Cadherin 8",
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        "tax_id": 9823,
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        "go_biological_process": "GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016477 cell migration;GO:0000902 cell morphogenesis;GO:0007043 cell-cell junction assembly;GO:0034332 adherens junction organization",
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        "protein_name": "TATA-box binding protein associated factor 4b",
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        "protein_names_uniprotkb": "TATA-box binding protein associated factor 4b",
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        "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0006366 transcription by RNA polymerase II;GO:0006352 DNA-templated transcription initiation;GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter",
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        "protein_names_uniprotkb": "Solute carrier family 25 member 47; Mitochondrial NAD(+) transporter SLC25A47",
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        "go_cellular_component": "GO:0098592 cytoplasmic side of apical plasma membrane;GO:0032541 cortical endoplasmic reticulum;GO:0140268 endoplasmic reticulum-plasma membrane contact site",
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    },
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        "protein_names_refseq": "Interphotoreceptor retinoid-binding protein; Interstitial retinol-binding protein; Retinol-binding protein 3; excision repair cross-complementing rodent repair deficiency, complementation group 6; interphotoreceptor retinoid binding protein; retinol-binding protein 3 precursor",
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        ],
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        "refseq_name": "transmembrane protein 59-like precursor",
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            {
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        "pathway": " (R-SSC-112382);  (R-SSC-113418);  (R-SSC-5696395);  (R-SSC-5696400);  (R-SSC-674695);  (R-SSC-6781823);  (R-SSC-6782135);  (R-SSC-6782210);  (R-SSC-6796648);  (R-SSC-72086);  (R-SSC-73762);  (R-SSC-73772);  (R-SSC-73776);  (R-SSC-73779);  (R-SSC-73863);  (R-SSC-75953);  (R-SSC-75955);  (R-SSC-76042);  (R-SSC-77075)",
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            {
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        "function": "Transcriptional activator. Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "protein_name": "ASXL transcriptional regulator 2",
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        "protein_name": "Suppressor of IKBKE 1",
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        "organism": "Pig",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "SIKE1",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Suppressor of IKBKE 1; Suppressor of IKK-epsilon",
        "protein_names_refseq": "",
        "tax_id": 9823,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 1,
        "publication_id_list": "32543654",
        "class_list": "",
        "function": "Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and RIGI. Does not inhibit NF-kappa-B activation pathways. Associates with the striatin-interacting phosphatase and kinase (STRIPAK) core complex, forming the extended (SIKE1:SLMAP)STRIPAK complex. The (SIKE1:SLMAP)STRIPAK complex dephosphorylates STK3 leading to the inhibition of Hippo signaling and the control of cell growth., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
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        "mined_c_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "disease_count": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0019901 protein kinase binding;GO:0030674 protein-macromolecule adaptor activity;GO:0031267 small GTPase binding",
        "go_cellular_component": "GO:0090443 FAR/SIN/STRIPAK complex",
        "go_biological_process": "GO:0035331 negative regulation of hippo signaling",
        "synthesized_glycan_count": 0,
        "hit_score": 0.2,
        "record_id": "F1SBS2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "F1SE30-1",
        "uniprot_id": [
            {
                "id": "F1SE30_PIG",
                "url": "https://www.uniprot.org/uniprot/F1SE30",
                "type": "external"
            }
        ],
        "mass": 204468.0,
        "length": 1865,
        "protein_name": "Ankyrin-1",
        "gene_name": "ANK1",
        "organism": "Pig",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "ANK1",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Ankyrin-1; Erythrocyte ankyrin",
        "protein_names_refseq": "",
        "tax_id": 9823,
        "disease": "",
        "pathway": " (R-SSC-447043);  (R-SSC-6807878)",
        "pathway_count": 2,
        "publication_count": 1,
        "publication_id_list": "32543654",
        "class_list": "",
        "function": "Component of the ankyrin-1 complex, a multiprotein complex involved in the stability and shape of the erythrocyte membrane. Attaches integral membrane proteins to cytoskeletal elements; binds to the erythrocyte membrane protein band 4.2, to Na-K ATPase, to the lymphocyte membrane protein GP85, and to the cytoskeletal proteins fodrin, tubulin, vimentin and desmin. Erythrocyte ankyrins also link spectrin (beta chain) to the cytoplasmic domain of the erythrocytes anion exchange protein; they retain most or all of these binding functions., [UniProtKB, UniProtKB, UniProtKB]",
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0051117 ATPase binding;GO:0044325 transmembrane transporter binding;GO:0030507 spectrin binding;GO:0008093 cytoskeletal anchor activity;GO:0019903 protein phosphatase binding",
        "go_cellular_component": "GO:0016020 membrane;GO:0071944 cell periphery;GO:0014731 spectrin-associated cytoskeleton;GO:0016529 sarcoplasmic reticulum;GO:0005886 plasma membrane",
        "go_biological_process": "GO:0007165 signal transduction;GO:0072659 protein localization to plasma membrane;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport",
        "synthesized_glycan_count": 0,
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        "record_type": "protein",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "F1SA39-1",
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            {
                "id": "F1SA39_PIG",
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                "type": "external"
            }
        ],
        "mass": 39889.0,
        "length": 353,
        "protein_name": "Pleckstrin-2",
        "gene_name": "PLEK2",
        "organism": "Pig",
        "refseq_name": "pleckstrin-2 isoform X2",
        "refseq_ac": [
            {
                "id": "XP_001928470",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928470",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "PLEK2",
        "gene_names_refseq": "PLEK2",
        "protein_names_uniprotkb": "Pleckstrin-2",
        "protein_names_refseq": "pleckstrin-2 isoform X2",
        "tax_id": 9823,
        "disease": "",
        "pathway": " (ssc:100154251)",
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        "publication_id_list": "32543654",
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        "ec_number_list": [],
        "go_molecular_function": "GO:0043325 phosphatidylinositol-3,4-bisphosphate binding;GO:0080025 phosphatidylinositol-3,5-bisphosphate binding;GO:0032266 phosphatidylinositol-3-phosphate binding",
        "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0031258 lamellipodium membrane",
        "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0030036 actin cytoskeleton organization;GO:0120034 positive regulation of plasma membrane bounded cell projection assembly;GO:0043131 erythrocyte enucleation",
        "synthesized_glycan_count": 0,
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        "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "F1SE79-1",
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            {
                "id": "F1SE79_PIG",
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                "type": "external"
            }
        ],
        "mass": 33992.0,
        "length": 292,
        "protein_name": "DCN1-like protein",
        "gene_name": "DCUN1D4",
        "organism": "Pig",
        "refseq_name": "DCN1-like protein 4 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005666699",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666699",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "DCUN1D4",
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        "protein_names_uniprotkb": "DCN1-like protein; Defective in cullin neddylation protein 1-like protein",
        "protein_names_refseq": "DCN1-like protein 4 isoform X1",
        "tax_id": 9823,
        "disease": "",
        "pathway": " (ssc:100521504);  (R-SSC-8951664)",
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        "ec_number_list": [],
        "go_molecular_function": "GO:0032182 ubiquitin-like protein binding;GO:0097602 cullin family protein binding;GO:0031624 ubiquitin conjugating enzyme binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0000151 ubiquitin ligase complex",
        "go_biological_process": "GO:0045116 protein neddylation;GO:2000436 positive regulation of protein neddylation",
        "synthesized_glycan_count": 0,
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        "record_id": "F1SE79-1",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "F1S8S5-1",
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            }
        ],
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        "protein_name": "Transmembrane protein 129, E3 ubiquitin ligase",
        "gene_name": "TMEM129",
        "organism": "Pig",
        "refseq_name": "E3 ubiquitin-protein ligase TM129 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_003128850",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128850",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "TMEM129",
        "gene_names_refseq": "TMEM129",
        "protein_names_uniprotkb": "Transmembrane protein 129, E3 ubiquitin ligase",
        "protein_names_refseq": "E3 ubiquitin-protein ligase TM129 isoform X1",
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        "go_molecular_function": "GO:0061630 ubiquitin protein ligase activity",
        "go_cellular_component": "GO:0016020 membrane;GO:0005783 endoplasmic reticulum",
        "go_biological_process": "GO:0016567 protein ubiquitination;GO:0000209 protein polyubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0030970 retrograde protein transport, ER to cytosol",
        "synthesized_glycan_count": 0,
        "hit_score": 0.2,
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    },
    {
        "uniprot_canonical_ac": "F1SAH1-1",
        "uniprot_id": [
            {
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                "url": "https://www.uniprot.org/uniprot/F1SAH1",
                "type": "external"
            }
        ],
        "mass": 107569.0,
        "length": 975,
        "protein_name": "NLR family member X1",
        "gene_name": "NLRX1",
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        "refseq_name": "NLR family member X1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005667461",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005667461",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "NLRX1",
        "gene_names_refseq": "NLRX1",
        "protein_names_uniprotkb": "NLR family member X1",
        "protein_names_refseq": "NLR family member X1 isoform X1",
        "tax_id": 9823,
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        "function": "Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction. Instead, promotes autophagy by interacting with TUFM and subsequently recruiting the autophagy-related proteins ATG5 and ATG12. Also regulates MAVS-dependent NLRP3 inflammasome activation to attenuate apoptosis. Has no inhibitory function on NF-kappa-B signaling pathway, but enhances NF-kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species. Regulates viral mediated-inflammation and energy metabolism in a sex-dependent manner. In females, prevents uncontrolled inflammation and energy metabolism and thus, may contribute to the sex differences observed in infectious and inflammatory diseases., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0005524 ATP binding",
        "go_cellular_component": "GO:0005741 mitochondrial outer membrane",
        "go_biological_process": "GO:0045087 innate immune response",
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        "hit_score": 0.2,
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    },
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            {
                "id": "F1SEP7_PIG",
                "url": "https://www.uniprot.org/uniprot/F1SEP7",
                "type": "external"
            }
        ],
        "mass": 34149.0,
        "length": 310,
        "protein_name": "RPE-retinal G protein-coupled receptor",
        "gene_name": "RGR",
        "organism": "Pig",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "RGR",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "RPE-retinal G protein-coupled receptor",
        "protein_names_refseq": "",
        "tax_id": 9823,
        "disease": "",
        "pathway": " (R-SSC-418594);  (R-SSC-419771)",
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        "class_list": "",
        "function": "Receptor for all-trans- and 11-cis-retinal. Binds preferentially to the former and may catalyze the isomerization of the chromophore by a retinochrome-like mechanism., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0003993 acid phosphatase activity;GO:0052642 lysophosphatidic acid phosphatase activity",
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            {
                "id": "XP_020937750",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937750",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC100153496",
        "gene_names_refseq": "LOC100153496",
        "protein_names_uniprotkb": "Olfactory receptor",
        "protein_names_refseq": "olfactory receptor 4M1-like",
        "tax_id": 9823,
        "disease": "",
        "pathway": " (ssc:100153496)",
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        "function": "Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "",
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        "kg_view_protein": true
    },
    {
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            {
                "id": "F1S7R4_PIG",
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            }
        ],
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        "length": 478,
        "protein_name": "Major facilitator superfamily domain-containing protein 12",
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        "organism": "Pig",
        "refseq_name": "major facilitator superfamily domain-containing protein 12 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005654765",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005654765",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "MFSD12",
        "gene_names_refseq": "MFSD12",
        "protein_names_uniprotkb": "Major facilitator superfamily domain-containing protein 12",
        "protein_names_refseq": "major facilitator superfamily domain-containing protein 12 isoform X1",
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        "disease": "",
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        "go_molecular_function": "GO:0015293 symporter activity;GO:0033229 cysteine transmembrane transporter activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0005765 lysosomal membrane;GO:0005770 late endosome;GO:0033162 melanosome membrane",
        "go_biological_process": "GO:0048022 negative regulation of melanin biosynthetic process;GO:0008643 carbohydrate transport;GO:0042438 melanin biosynthetic process;GO:1903712 cysteine transmembrane transport;GO:0048021 regulation of melanin biosynthetic process",
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    },
    {
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                "id": "F1S7S1_PIG",
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            }
        ],
        "mass": 76396.0,
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        "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 2",
        "gene_name": "TAB2",
        "organism": "Pig",
        "refseq_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_013847953",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013847953",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "TAB2",
        "gene_names_refseq": "TAB2",
        "protein_names_uniprotkb": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 2; Mitogen-activated protein kinase kinase kinase 7-interacting protein 2; TGF-beta-activated kinase 1-binding protein 2",
        "protein_names_refseq": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1",
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        "disease": "",
        "pathway": " (ssc:100156182);  (R-SSC-168638);  (R-SSC-202424);  (R-SSC-2871837);  (R-SSC-445989);  (R-SSC-450302);  (R-SSC-450321);  (R-SSC-5357956);  (R-SSC-5607764);  (R-SSC-9020702);  (R-SSC-937042);  (R-SSC-937072);  (R-SSC-9645460);  (R-SSC-975163)",
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        "function": "Adapter required to activate the JNK and NF-kappa-B signaling pathways through the specific recognition of 'Lys-63'-linked polyubiquitin chains by its RanBP2-type zinc finger (NZF). Acts as an adapter linking MAP3K7/TAK1 and TRAF6 to 'Lys-63'-linked polyubiquitin chains. The RanBP2-type zinc finger (NZF) specifically recognizes Lys-63'-linked polyubiquitin chains unanchored or anchored to the substrate proteins such as RIPK1/RIP1 and RIPK2: this acts as a scaffold to organize a large signaling complex to promote autophosphorylation of MAP3K7/TAK1, and subsequent activation of I-kappa-B-kinase (IKK) core complex by MAP3K7/TAK1. Also recognizes and binds Lys-63'-linked polyubiquitin chains of heterotypic 'Lys-63'-/'Lys-48'-linked branched ubiquitin chains. Regulates the IL1-mediated translocation of NCOR1 out of the nucleus. Involved in heart development., [UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0008270 zinc ion binding;GO:0016301 kinase activity;GO:0043130 ubiquitin binding;GO:0070530 K63-linked polyubiquitin modification-dependent protein binding",
        "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005765 lysosomal membrane;GO:0010008 endosome membrane",
        "go_biological_process": "GO:0006954 inflammatory response;GO:0007507 heart development;GO:0032496 response to lipopolysaccharide;GO:0043123 positive regulation of canonical NF-kappaB signal transduction;GO:0042742 defense response to bacterium",
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    },
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            }
        ],
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        "length": 507,
        "protein_name": "Zinc finger CCCH-type containing 12D",
        "gene_name": "ZC3H12D",
        "organism": "Pig",
        "refseq_name": "probable ribonuclease ZC3H12D",
        "refseq_ac": [
            {
                "id": "XP_003121206",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121206",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ZC3H12D",
        "gene_names_refseq": "ZC3H12D",
        "protein_names_uniprotkb": "Zinc finger CCCH-type containing 12D",
        "protein_names_refseq": "probable ribonuclease ZC3H12D",
        "tax_id": 9823,
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        "go_molecular_function": "GO:0003729 mRNA binding;GO:0008270 zinc ion binding;GO:0016787 hydrolase activity;GO:0004521 RNA endonuclease activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0000932 P-body;GO:0036464 cytoplasmic ribonucleoprotein granule",
        "go_biological_process": "GO:0061158 3'-UTR-mediated mRNA destabilization",
        "synthesized_glycan_count": 0,
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        "record_id": "F1S7S2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000",
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    },
    {
        "uniprot_canonical_ac": "F1S7S8-1",
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            {
                "id": "F1S7S8_PIG",
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                "type": "external"
            }
        ],
        "mass": 78638.0,
        "length": 699,
        "protein_name": "eEF1A lysine and N-terminal methyltransferase",
        "gene_name": "METTL13",
        "organism": "Pig",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "METTL13",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "eEF1A lysine and N-terminal methyltransferase; Methyltransferase-like protein 13",
        "protein_names_refseq": "",
        "tax_id": 9823,
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        "function": "Dual methyltransferase that catalyzes methylation of elongation factor 1-alpha (EEF1A1 and EEF1A2) at two different positions, and is therefore involved in the regulation of mRNA translation. Via its C-terminus, methylates EEF1A1 and EEF1A2 at the N-terminal residue 'Gly-2'. Via its N-terminus dimethylates EEF1A1 and EEF1A2 at residue 'Lys-55'. Has no activity towards core histones H2A, H2B, H3 and H4., [UniProtKB, UniProtKB]",
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        "secondary_ac_list": "A0A287AUQ7",
        "ec_number_list": [],
        "go_molecular_function": "GO:0016279 protein-lysine N-methyltransferase activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005829 cytosol",
        "go_biological_process": "GO:0032259 methylation",
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        "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000",
        "kg_view_protein": true
    },
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        ],
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        "length": 505,
        "protein_name": "Low-density lipoprotein receptor-related protein 11",
        "gene_name": "LRP11",
        "organism": "Pig",
        "refseq_name": "low-density lipoprotein receptor-related protein 11",
        "refseq_ac": [
            {
                "id": "XP_001929023",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929023",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LRP11",
        "gene_names_refseq": "LRP11",
        "protein_names_uniprotkb": "Low-density lipoprotein receptor-related protein 11",
        "protein_names_refseq": "low-density lipoprotein receptor-related protein 11",
        "tax_id": 9823,
        "disease": "",
        "pathway": " (ssc:100153355)",
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0051219 phosphoprotein binding",
        "go_cellular_component": "GO:0016020 membrane",
        "go_biological_process": "GO:0009409 response to cold;GO:0042594 response to starvation;GO:0009612 response to mechanical stimulus;GO:0009414 response to water deprivation;GO:0009408 response to heat",
        "synthesized_glycan_count": 0,
        "hit_score": 0.2,
        "record_id": "F1S7T8-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "F1S7V0-1",
        "uniprot_id": [
            {
                "id": "F1S7V0_PIG",
                "url": "https://www.uniprot.org/uniprot/F1S7V0",
                "type": "external"
            }
        ],
        "mass": 34545.0,
        "length": 310,
        "protein_name": "Olfactory receptor",
        "gene_name": "",
        "organism": "Pig",
        "refseq_name": "olfactory receptor 13-like",
        "refseq_ac": [
            {
                "id": "XP_003130340",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130340",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "",
        "gene_names_refseq": "LOC100511466",
        "protein_names_uniprotkb": "Olfactory receptor",
        "protein_names_refseq": "olfactory receptor 13-like",
        "tax_id": 9823,
        "disease": "",
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        "publication_id_list": "32543654",
        "class_list": "",
        "function": "Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0015026 coreceptor activity;GO:0019901 protein kinase binding;GO:0019955 cytokine binding;GO:0004896 cytokine receptor activity",
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        "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0035722 interleukin-12-mediated signaling pathway;GO:0032729 positive regulation of type II interferon production;GO:0019221 cytokine-mediated signaling pathway",
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    },
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            {
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            }
        ],
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        "protein_name": "Calcium homeostasis modulator 1",
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        "protein_names_uniprotkb": "Calcium homeostasis modulator 1",
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        "go_biological_process": "GO:0051260 protein homooligomerization;GO:0051291 protein heterooligomerization;GO:0034765 regulation of monoatomic ion transmembrane transport;GO:0050913 sensory perception of bitter taste;GO:0050916 sensory perception of sweet taste",
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            }
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        "refseq_name": "transcription initiation factor TFIID subunit 5",
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            {
                "id": "XP_020929143",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020929143",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "TAF5",
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        "pathway": " (ssc:100152210);  (R-SSC-674695);  (R-SSC-6804756);  (R-SSC-6807505);  (R-SSC-73776);  (R-SSC-73779);  (R-SSC-75953);  (R-SSC-76042)",
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        "function": "The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. The TFIID complex structure can be divided into 3 modules TFIID-A, TFIID-B, and TFIID-C. TAF5 is involved in two modules of TFIID, in TFIID-A together with TAF3 and TBP, and in TFIID-B with TAF8. Involved in contacts between TFIID and TFIIF in the PIC., [UniProtKB, UniProtKB]",
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        ],
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        "protein_name": "Internexin neuronal intermediate filament protein alpha",
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        "refseq_name": "alpha-internexin",
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            {
                "id": "XP_001929355",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929355",
                "type": "external"
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        ],
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        "go_molecular_function": "GO:0099184 structural constituent of postsynaptic intermediate filament cytoskeleton",
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                "type": "external"
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        ],
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        "protein_name": "Sulfiredoxin",
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        "protein_names_uniprotkb": "Sulfiredoxin; 1.8.98.2",
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        "function": "Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase., [UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0005524 ATP binding;GO:0032542 sulfiredoxin activity",
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        "protein_name": "Family with sequence similarity 110 member A",
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        "refseq_name": "protein FAM110A",
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            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013840665",
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            }
        ],
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        "go_cellular_component": "GO:0000922 spindle pole;GO:0005634 nucleus;GO:0005813 centrosome;GO:0005829 cytosol;GO:0005938 cell cortex",
        "go_biological_process": "GO:0007052 mitotic spindle organization",
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        ],
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        "length": 469,
        "protein_name": "Riboflavin transporter",
        "gene_name": "SLC52A3",
        "organism": "Pig",
        "refseq_name": "solute carrier family 52, riboflavin transporter, member 3",
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            {
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        ],
        "gene_names_uniprotkb": "SLC52A3",
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        "function": "Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism., [UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0032217 riboflavin transmembrane transporter activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0007605 sensory perception of sound;GO:0032218 riboflavin transport",
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        ],
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