[ { "uniprot_canonical_ac": "A0A8C2QG42-1", "uniprot_id": [ { "id": "A0A8C2QG42_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QG42", "type": "external" } ], "mass": 78700.0, "length": 709, "protein_name": "Nicastrin", "gene_name": "Ncstn", "organism": "Hamster", "refseq_name": "nicastrin", "refseq_ac": [ { "id": "XP_007639161", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639161", "type": "external" } ], "gene_names_uniprotkb": "Ncstn", "gene_names_refseq": "Ncstn", "protein_names_uniprotkb": "Nicastrin", "protein_names_refseq": "nicastrin", "tax_id": 10029, "disease": "", "pathway": " (cge:100761836)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613783.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0051117 ATPase binding;GO:0070851 growth factor receptor binding;GO:0061133 endopeptidase activator activity;GO:0042500 aspartic endopeptidase activity, intramembrane cleaving", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005764 lysosome;GO:0030659 cytoplasmic vesicle membrane;GO:0042470 melanosome", "go_biological_process": "GO:0006509 membrane protein ectodomain proteolysis;GO:0007219 Notch signaling pathway;GO:0007220 Notch receptor processing;GO:0016485 protein processing;GO:0031293 membrane protein intracellular domain proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QG42-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QGE7-1", "uniprot_id": [ { "id": "A0A8C2QGE7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QGE7", "type": "external" } ], "mass": 36001.0, "length": 334, "protein_name": "Transcription factor Jun", "gene_name": "LOC113834001", "organism": "Hamster", "refseq_name": "transcription factor AP-1", "refseq_ac": [ { "id": "XP_027256232", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256232", "type": "external" } ], "gene_names_uniprotkb": "LOC113834001", "gene_names_refseq": "LOC113834001", "protein_names_uniprotkb": "Transcription factor Jun; Activator protein 1; Proto-oncogene c-Jun; Transcription factor AP-1 subunit Jun; V-jun avian sarcoma virus 17 oncogene homolog", "protein_names_refseq": "transcription factor AP-1", "tax_id": 10029, "disease": "", "pathway": " (cge:113834001)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0005096 GTPase activator activity;GO:0042802 identical protein binding;GO:0031625 ubiquitin protein ligase binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0017053 transcription repressor complex;GO:0000791 euchromatin;GO:0035976 transcription factor AP-1 complex", "go_biological_process": "GO:0019046 release from viral latency;GO:0006351 DNA-templated transcription;GO:0007254 JNK cascade;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0060395 SMAD protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QGE7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QGI9-1", "uniprot_id": [ { "id": "A0A8C2QGI9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QGI9", "type": "external" } ], "mass": 334168.0, "length": 2984, "protein_name": "ATP-dependent chromatin remodeler CHD7", "gene_name": "Chd7", "organism": "Hamster", "refseq_name": "chromodomain-helicase-DNA-binding protein 7 isoform X2", "refseq_ac": [ { "id": "XP_027254691", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254691", "type": "external" } ], "gene_names_uniprotkb": "Chd7", "gene_names_refseq": "Chd7", "protein_names_uniprotkb": "ATP-dependent chromatin remodeler CHD7; Chromo domain-containing protein 7", "protein_names_refseq": "chromodomain-helicase-DNA-binding protein 7 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100755474)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; ATP-dependent chromatin-remodeling factor, slides nucleosomes along DNA; nucleosome sliding requires ATP. Probable transcription regulator. May be involved in the in 45S precursor rRNA production., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:1990841 promoter-specific chromatin binding;GO:0003677 DNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005634 nucleus", "go_biological_process": "GO:0021545 cranial nerve development;GO:0043584 nose development;GO:0048806 genitalia development;GO:0060123 regulation of growth hormone secretion;GO:0001701 in utero embryonic development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QGI9-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QGR8-1", "uniprot_id": [ { "id": "A0A8C2QGR8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QGR8", "type": "external" } ], "mass": 44215.0, "length": 395, "protein_name": "Proteinase-activated receptor 2 isoform X1", "gene_name": "F2rl1", "organism": "Hamster", "refseq_name": "proteinase-activated receptor 2 isoform X1", "refseq_ac": [ { "id": "XP_007630279", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007630279", "type": "external" } ], "gene_names_uniprotkb": "F2rl1", "gene_names_refseq": "F2rl1", "protein_names_uniprotkb": "Proteinase-activated receptor 2 isoform X1", "protein_names_refseq": "proteinase-activated receptor 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100757860)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613700.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015057 thrombin-activated receptor activity;GO:0031681 G-protein beta-subunit binding;GO:0002020 protease binding;GO:0001965 G-protein alpha-subunit binding", "go_cellular_component": "GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0031143 pseudopodium", "go_biological_process": "GO:0034141 positive regulation of toll-like receptor 3 signaling pathway;GO:0061028 establishment of endothelial barrier;GO:1900135 positive regulation of renin secretion into blood stream;GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0032930 positive regulation of superoxide anion generation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QGR8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QH91-1", "uniprot_id": [ { "id": "A0A8C2QH91_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QH91", "type": "external" } ], "mass": 177077.0, "length": 1559, "protein_name": "Chromatin-remodeling ATPase INO80", "gene_name": "Ino80", "organism": "Hamster", "refseq_name": "chromatin-remodeling ATPase INO80 isoform X1", "refseq_ac": [ { "id": "XP_003512652", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512652", "type": "external" } ], "gene_names_uniprotkb": "Ino80", "gene_names_refseq": "Ino80", "protein_names_uniprotkb": "Chromatin-remodeling ATPase INO80; 3.6.4.-", "protein_names_refseq": "chromatin-remodeling ATPase INO80 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100762469)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615513.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair., [UniProtKB, UniProtKB, UniProtKB]; ATPase component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and DNA repair. Binds DNA. As part of the INO80 complex, remodels chromatin by shifting nucleosomes. Regulates transcription upon recruitment by YY1 to YY1-activated genes, where it acts as an essential coactivator. Involved in UV-damage excision DNA repair. The contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation. Involved in DNA replication. Required for microtubule assembly during mitosis thereby regulating chromosome segregation cycle., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0003779 actin binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0042393 histone binding", "go_cellular_component": "GO:0005819 spindle;GO:0005829 cytosol;GO:0005874 microtubule;GO:0031011 Ino80 complex;GO:0016604 nuclear body", "go_biological_process": "GO:0060382 regulation of DNA strand elongation;GO:0006351 DNA-templated transcription;GO:0030307 positive regulation of cell growth;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0051301 cell division", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QH91-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QHS8-1", "uniprot_id": [ { "id": "A0A8C2QHS8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QHS8", "type": "external" } ], "mass": 74641.0, "length": 659, "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "Ripk1", "organism": "Hamster", "refseq_name": "receptor-interacting serine/threonine-protein kinase 1", "refseq_ac": [ { "id": "XP_003513240", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513240", "type": "external" } ], "gene_names_uniprotkb": "Ripk1", "gene_names_refseq": "Ripk1", "protein_names_uniprotkb": "Receptor-interacting serine/threonine-protein kinase 1; 2.7.11.1; Cell death protein RIP; Receptor-interacting protein 1", "protein_names_refseq": "receptor-interacting serine/threonine-protein kinase 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100761116)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615775.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0070513 death domain binding;GO:0005524 ATP binding;GO:0042803 protein homodimerization activity;GO:0031625 ubiquitin protein ligase binding;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0043235 receptor complex;GO:0097342 ripoptosome;GO:0031264 death-inducing signaling complex", "go_biological_process": "GO:0070105 positive regulation of interleukin-6-mediated signaling pathway;GO:0006954 inflammatory response;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0046330 positive regulation of JNK cascade;GO:1990000 amyloid fibril formation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QHS8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QIA1-1", "uniprot_id": [ { "id": "A0A8C2QIA1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QIA1", "type": "external" } ], "mass": 83560.0, "length": 737, "protein_name": "Protein kinase C epsilon type", "gene_name": "Prkce", "organism": "Hamster", "refseq_name": "protein kinase C epsilon type", "refseq_ac": [ { "id": "XP_003496276", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496276", "type": "external" } ], "gene_names_uniprotkb": "Prkce", "gene_names_refseq": "Prkce", "protein_names_uniprotkb": "Protein kinase C epsilon type; 2.7.11.13; nPKC-epsilon", "protein_names_refseq": "protein kinase C epsilon type", "tax_id": 10029, "disease": "", "pathway": " (cge:100763552)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613615.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin-dependent signaling, by mediating angiotensin-2-induced activation of integrin beta-1 (ITGB1) in cardiac fibroblasts. Phosphorylates MARCKS, which phosphorylates and activates PTK2/FAK, leading to the spread of cardiomyocytes. Involved in the control of the directional transport of ITGB1 in mesenchymal cells by phosphorylating vimentin (VIM), an intermediate filament (IF) protein. In epithelial cells, associates with and phosphorylates keratin-8 (KRT8), which induces targeting of desmoplakin at desmosomes and regulates cell-cell contact. Phosphorylates IQGAP1, which binds to CDC42, mediating epithelial cell-cell detachment prior to migration., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity;GO:0003785 actin monomer binding;GO:0005524 ATP binding;GO:0008047 enzyme activator activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005829 cytosol", "go_biological_process": "GO:0035669 TRAM-dependent toll-like receptor 4 signaling pathway;GO:0007155 cell adhesion;GO:0051301 cell division;GO:0090303 positive regulation of wound healing;GO:0042178 xenobiotic catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QIA1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QIH6-1", "uniprot_id": [ { "id": "A0A8C2QIH6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QIH6", "type": "external" } ], "mass": 35807.0, "length": 320, "protein_name": "Acyl-coenzyme A thioesterase 8", "gene_name": "LOC100761464", "organism": "Hamster", "refseq_name": "acyl-coenzyme A thioesterase 8 isoform X1", "refseq_ac": [ { "id": "XP_003504633", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504633", "type": "external" } ], "gene_names_uniprotkb": "LOC100761464", "gene_names_refseq": "LOC100761464", "protein_names_uniprotkb": "Acyl-coenzyme A thioesterase 8; 3.1.2.11; 3.1.2.1; 3.1.2.27; 3.1.2.2; 3.1.2.3; 3.1.2.5; Choloyl-coenzyme A thioesterase; Peroxisomal acyl-coenzyme A thioester hydrolase 1; Peroxisomal long-chain acyl-CoA thioesterase 1", "protein_names_refseq": "acyl-coenzyme A thioesterase 8 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100761464)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 301 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614077.1) and transcript sequence (IACG01041286.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003504633.4. COMPLETENESS: full length., [RefSeq]; Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Displays no strong substrate specificity with respect to the carboxylic acid moiety of Acyl-CoAs. Hydrolyzes medium length (C2 to C20) straight-chain, saturated and unsaturated acyl-CoAS but is inactive towards substrates with longer aliphatic chains. Moreover, it catalyzes the hydrolysis of CoA esters of bile acids, such as choloyl-CoA and chenodeoxycholoyl-CoA and competes with bile acid CoA:amino acid N-acyltransferase (BAAT). Is also able to hydrolyze CoA esters of dicarboxylic acids. It is involved in the metabolic regulation of peroxisome proliferation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "3.1.2.14", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.14", "type": "external" }, { "id": "3.1.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.27", "type": "external" }, { "id": "3.1.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.1", "type": "external" }, { "id": "3.1.2.11", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.11", "type": "external" }, { "id": "3.1.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.3", "type": "external" }, { "id": "3.1.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.5", "type": "external" }, { "id": "3.5.2.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.2.6", "type": "external" }, { "id": "3.1.2.22", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.22", "type": "external" } ], "go_molecular_function": "GO:0003986 acetyl-CoA hydrolase activity;GO:0004778 succinyl-CoA hydrolase activity;GO:0033882 choloyl-CoA hydrolase activity;GO:0052689 carboxylic ester hydrolase activity;GO:0052815 medium-chain fatty acyl-CoA hydrolase activity", "go_cellular_component": "GO:0005782 peroxisomal matrix", "go_biological_process": "GO:0006637 acyl-CoA metabolic process;GO:0009062 fatty acid catabolic process;GO:0016559 peroxisome fission;GO:0043649 dicarboxylic acid catabolic process;GO:0006633 fatty acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QIH6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QIS3-1", "uniprot_id": [ { "id": "A0A8C2QIS3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QIS3", "type": "external" } ], "mass": 47856.0, "length": 425, "protein_name": "Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial", "gene_name": "LOC100771752", "organism": "Hamster", "refseq_name": "kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform X2", "refseq_ac": [ { "id": "XP_027249886", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249886", "type": "external" } ], "gene_names_uniprotkb": "LOC100771752", "gene_names_refseq": "LOC100771752", "protein_names_uniprotkb": "Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; 2-aminoadipate aminotransferase; 2-aminoadipate transaminase; 2.6.1.39; 2.6.1.4; 2.6.1.63; 2.6.1.73; 2.6.1.7; Alpha-aminoadipate aminotransferase; Glycine transaminase AADAT; Kynurenine aminotransferase II; Kynurenine--glyoxylate transaminase AADAT; Kynurenine--oxoglutarate aminotransferase II; Kynurenine--oxoglutarate transaminase 2; Kynurenine--oxoglutarate transaminase II; Methionine--glyoxylate transaminase AADAT", "protein_names_refseq": "kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100771752)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.6.1.64", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.64", "type": "external" }, { "id": "4.4.1.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.4.1.13", "type": "external" }, { "id": "2.6.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.7", "type": "external" }, { "id": "2.6.1.63", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.63", "type": "external" }, { "id": "2.6.1.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.39", "type": "external" }, { "id": "2.6.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.4", "type": "external" }, { "id": "2.6.1.73", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.73", "type": "external" }, { "id": "2.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.1", "type": "external" } ], "go_molecular_function": "GO:0047315 kynurenine-glyoxylate transaminase activity;GO:0016212 kynurenine-oxoglutarate transaminase activity;GO:0030170 pyridoxal phosphate binding;GO:0042803 protein homodimerization activity;GO:0047536 2-aminoadipate transaminase activity", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006103 2-oxoglutarate metabolic process;GO:0006536 glutamate metabolic process;GO:0070189 kynurenine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QIS3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJ57-1", "uniprot_id": [ { "id": "A0A8C2QJ57_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJ57", "type": "external" } ], "mass": 47603.0, "length": 428, "protein_name": "Proteinase-activated receptor 1", "gene_name": "F2r", "organism": "Hamster", "refseq_name": "proteinase-activated receptor 1 isoform X1", "refseq_ac": [ { "id": "XP_003498759", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498759", "type": "external" } ], "gene_names_uniprotkb": "F2r", "gene_names_refseq": "F2r", "protein_names_uniprotkb": "Proteinase-activated receptor 1; Thrombin receptor", "protein_names_refseq": "proteinase-activated receptor 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100758351)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 188 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613700.1) and transcript sequence (IACG01121795.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003498759.4. COMPLETENESS: full length., [RefSeq]; High affinity receptor that binds the activated thrombin, leading to calcium release from intracellular stores. The thrombin-activated receptor signaling pathway is mediated through PTX-insensitive G proteins, activation of phospholipase C resulting in the production of 1D-myo-inositol 1,4,5-trisphosphate (InsP3) which binds to InsP3 receptors causing calcium release from the stores. In astrocytes, the calcium released into the cytosol allows the Ca(2+)-dependent release of L-glutamate into the synaptic cleft through BEST1, that targets the neuronal postsynaptic GRIN2A/NMDAR receptor resulting in the synaptic plasticity regulation. May play a role in platelets activation and in vascular development. Mediates up-regulation of pro-inflammatory cytokines, such as MCP-1/CCL2 and IL6, triggered by coagulation factor Xa (F10) in cardiac fibroblasts and umbilical vein endothelial cells., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015057 thrombin-activated receptor activity;GO:0031681 G-protein beta-subunit binding;GO:0005102 signaling receptor binding;GO:0001965 G-protein alpha-subunit binding", "go_cellular_component": "GO:0031094 platelet dense tubular network;GO:0005769 early endosome;GO:0009986 cell surface;GO:0045202 synapse;GO:0005770 late endosome", "go_biological_process": "GO:1900134 negative regulation of renin secretion into blood stream;GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0008285 negative regulation of cell population proliferation;GO:0030335 positive regulation of cell migration;GO:0043065 positive regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJ57-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJE4-1", "uniprot_id": [ { "id": "A0A8C2QJE4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJE4", "type": "external" } ], "mass": 63878.0, "length": 576, "protein_name": "5'-nucleotidase", "gene_name": "Nt5e", "organism": "Hamster", "refseq_name": "5'-nucleotidase isoform X1", "refseq_ac": [ { "id": "XP_003495677", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495677", "type": "external" } ], "gene_names_uniprotkb": "Nt5e", "gene_names_refseq": "Nt5e", "protein_names_uniprotkb": "5'-nucleotidase; 3.1.3.35; 3.1.3.5; 3.1.3.89; 3.1.3.91; 3.1.3.99; 5'-deoxynucleotidase; Ecto-5'-nucleotidase; IMP-specific 5'-nucleotidase; Thymidylate 5'-phosphatase", "protein_names_refseq": "5'-nucleotidase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100759374)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.5", "type": "external" }, { "id": "3.1.3.89", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.89", "type": "external" }, { "id": "3.1.3.91", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.91", "type": "external" }, { "id": "3.1.3.99", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.99", "type": "external" }, { "id": "3.1.3.35", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.35", "type": "external" }, { "id": "3.1.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.1", "type": "external" }, { "id": "3.6.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.9", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "2.7.1.77", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.77", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0000166 nucleotide binding;GO:0008253 5'-nucleotidase activity;GO:0002953 5'-deoxynucleotidase activity", "go_cellular_component": "GO:0009897 external side of plasma membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0046032 ADP catabolic process;GO:0006196 AMP catabolic process;GO:0007159 leukocyte cell-cell adhesion;GO:0046086 adenosine biosynthetic process;GO:0031214 biomineral tissue development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJE4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJR3-1", "uniprot_id": [ { "id": "A0A8C2QJR3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJR3", "type": "external" } ], "mass": 59471.0, "length": 588, "protein_name": "Transcription factor GATA-6 isoform X2", "gene_name": "Gata6", "organism": "Hamster", "refseq_name": "transcription factor GATA-6 isoform X2", "refseq_ac": [ { "id": "XP_027260127", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260127", "type": "external" } ], "gene_names_uniprotkb": "Gata6", "gene_names_refseq": "Gata6", "protein_names_uniprotkb": "Transcription factor GATA-6 isoform X2", "protein_names_refseq": "transcription factor GATA-6 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:103161469)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051525 NFAT protein binding;GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0019901 protein kinase binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0002759 regulation of antimicrobial humoral response;GO:0098773 skin epidermis development;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0043066 negative regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJR3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJV6-1", "uniprot_id": [ { "id": "A0A8C2QJV6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJV6", "type": "external" } ], "mass": 35402.0, "length": 314, "protein_name": "Secreted frizzled-related protein 1", "gene_name": "Sfrp1", "organism": "Hamster", "refseq_name": "secreted frizzled-related protein 1 isoform X2", "refseq_ac": [ { "id": "XP_027251106", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251106", "type": "external" } ], "gene_names_uniprotkb": "Sfrp1", "gene_names_refseq": "Sfrp1", "protein_names_uniprotkb": "Secreted frizzled-related protein 1", "protein_names_refseq": "secreted frizzled-related protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754312)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels. Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase. In kidney development, inhibits tubule formation and bud growth in metanephroi. Inhibits WNT1/WNT4-mediated TCF-dependent transcription., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005109 frizzled binding;GO:0008201 heparin binding;GO:0042802 identical protein binding;GO:0017147 Wnt-protein binding;GO:0004197 cysteine-type endopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005829 cytosol;GO:0009986 cell surface;GO:0031012 extracellular matrix", "go_biological_process": "GO:0045880 positive regulation of smoothened signaling pathway;GO:0046851 negative regulation of bone remodeling;GO:0008284 positive regulation of cell population proliferation;GO:0010629 negative regulation of gene expression;GO:0030307 positive regulation of cell growth", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJV6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJY0-1", "uniprot_id": [ { "id": "A0A8C2QJY0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJY0", "type": "external" } ], "mass": 46541.0, "length": 427, "protein_name": "Mothers against decapentaplegic homolog", "gene_name": "Smad7", "organism": "Hamster", "refseq_name": "mothers against decapentaplegic homolog 7 isoform X2", "refseq_ac": [ { "id": "XP_027253719", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253719", "type": "external" } ], "gene_names_uniprotkb": "Smad7", "gene_names_refseq": "Smad7", "protein_names_uniprotkb": "Mothers against decapentaplegic homolog; MAD homolog; Mothers against DPP homolog; SMAD family member", "protein_names_refseq": "mothers against decapentaplegic homolog 7 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100766709)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0003714 transcription corepressor activity;GO:0031625 ubiquitin protein ligase binding;GO:0005518 collagen binding;GO:0008013 beta-catenin binding", "go_cellular_component": "GO:0071144 heteromeric SMAD protein complex;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005912 adherens junction", "go_biological_process": "GO:0010717 regulation of epithelial to mesenchymal transition;GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization;GO:0002725 negative regulation of T cell cytokine production;GO:2000320 negative regulation of T-helper 17 cell differentiation;GO:0000122 negative regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJY0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QK57-1", "uniprot_id": [ { "id": "A0A8C2QK57_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QK57", "type": "external" } ], "mass": 70900.0, "length": 637, "protein_name": "SH3 domain-containing kinase-binding protein 1", "gene_name": "Cd2ap", "organism": "Hamster", "refseq_name": "CD2-associated protein isoform X2", "refseq_ac": [ { "id": "XP_027243271", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243271", "type": "external" } ], "gene_names_uniprotkb": "Cd2ap", "gene_names_refseq": "Cd2ap", "protein_names_uniprotkb": "SH3 domain-containing kinase-binding protein 1; Regulator of ubiquitous kinase; SH3-containing, expressed in tumorigenic astrocytes", "protein_names_refseq": "CD2-associated protein isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100770360)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017124 SH3 domain binding;GO:0051015 actin filament binding;GO:0030276 clathrin binding;GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding", "go_cellular_component": "GO:0005641 nuclear envelope lumen;GO:0005886 plasma membrane;GO:0005925 focal adhesion;GO:0030425 dendrite;GO:0030426 growth cone", "go_biological_process": "GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0016477 cell migration;GO:0050808 synapse organization;GO:0051058 negative regulation of small GTPase mediated signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QK57-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QK84-1", "uniprot_id": [ { "id": "A0A8C2QK84_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QK84", "type": "external" } ], "mass": 52530.0, "length": 456, "protein_name": "Glycine receptor subunit alpha-1 isoform X1", "gene_name": "Glra1", "organism": "Hamster", "refseq_name": "glycine receptor subunit alpha-1 isoform X1", "refseq_ac": [ { "id": "XP_027282010", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282010", "type": "external" } ], "gene_names_uniprotkb": "Glra1", "gene_names_refseq": "Glra1", "protein_names_uniprotkb": "Glycine receptor subunit alpha-1 isoform X1", "protein_names_refseq": "glycine receptor subunit alpha-1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100761438)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" } ], "go_molecular_function": "GO:0016934 extracellularly glycine-gated chloride channel activity;GO:0030977 taurine binding;GO:0004888 transmembrane signaling receptor activity;GO:0008270 zinc ion binding;GO:0016594 glycine binding", "go_cellular_component": "GO:0030425 dendrite;GO:0043204 perikaryon;GO:0045211 postsynaptic membrane;GO:0009897 external side of plasma membrane;GO:0034707 chloride channel complex", "go_biological_process": "GO:2000344 positive regulation of acrosome reaction;GO:0051970 negative regulation of transmission of nerve impulse;GO:0006936 muscle contraction;GO:0007218 neuropeptide signaling pathway;GO:0071361 cellular response to ethanol", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QK84-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KDV7-1", "uniprot_id": [ { "id": "A0A9J7KDV7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KDV7", "type": "external" } ], "mass": 56450.0, "length": 500, "protein_name": "Cyclin-dependent kinase 14", "gene_name": "Cdk14", "organism": "Hamster", "refseq_name": "cyclin-dependent kinase 14 isoform X4", "refseq_ac": [ { "id": "XP_035306502", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306502", "type": "external" } ], "gene_names_uniprotkb": "Cdk14", "gene_names_refseq": "Cdk14", "protein_names_uniprotkb": "Cyclin-dependent kinase 14; 2.7.11.22; 2.7.11.24; Cell division protein kinase 14", "protein_names_refseq": "cyclin-dependent kinase 14 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100769772)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004693 cyclin-dependent protein serine/threonine kinase activity;GO:0030332 cyclin binding;GO:0004707 MAP kinase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex;GO:0005769 early endosome", "go_biological_process": "GO:0051301 cell division;GO:0000086 G2/M transition of mitotic cell cycle;GO:0016055 Wnt signaling pathway;GO:0060828 regulation of canonical Wnt signaling pathway;GO:0072584 caveolin-mediated endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KDV7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QLB5-1", "uniprot_id": [ { "id": "A0A8C2QLB5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QLB5", "type": "external" } ], "mass": 17167.0, "length": 154, "protein_name": "Fibroblast growth factor", "gene_name": "Fgf2", "organism": "Hamster", "refseq_name": "fibroblast growth factor 2 isoform X2", "refseq_ac": [ { "id": "XP_027247762", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247762", "type": "external" } ], "gene_names_uniprotkb": "Fgf2", "gene_names_refseq": "Fgf2", "protein_names_uniprotkb": "Fibroblast growth factor; FGF", "protein_names_refseq": "fibroblast growth factor 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100757429)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0008201 heparin binding;GO:0042056 chemoattractant activity;GO:0042802 identical protein binding;GO:0005125 cytokine activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0016604 nuclear body", "go_biological_process": "GO:0010764 negative regulation of fibroblast migration;GO:1903672 positive regulation of sprouting angiogenesis;GO:1905564 positive regulation of vascular endothelial cell proliferation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QLB5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QLE7-1", "uniprot_id": [ { "id": "A0A8C2QLE7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QLE7", "type": "external" } ], "mass": 111913.0, "length": 1011, "protein_name": "Tyrosine-protein kinase Mer", "gene_name": "Mertk", "organism": "Hamster", "refseq_name": "tyrosine-protein kinase Mer isoform X1", "refseq_ac": [ { "id": "XP_035299011", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299011", "type": "external" } ], "gene_names_uniprotkb": "Mertk", "gene_names_refseq": "Mertk", "protein_names_uniprotkb": "Tyrosine-protein kinase Mer; 2.7.10.1; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK", "protein_names_refseq": "tyrosine-protein kinase Mer isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100755929)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613665.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0007399 nervous system development;GO:0016477 cell migration;GO:0006909 phagocytosis;GO:0050766 positive regulation of phagocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QLE7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QLK9-1", "uniprot_id": [ { "id": "A0A8C2QLK9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QLK9", "type": "external" } ], "mass": 244067.0, "length": 2317, "protein_name": "Neurogenic locus notch homolog protein 3", "gene_name": "Notch3", "organism": "Hamster", "refseq_name": "neurogenic locus notch homolog protein 3 isoform X3", "refseq_ac": [ { "id": "XP_027275284", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275284", "type": "external" } ], "gene_names_uniprotkb": "Notch3", "gene_names_refseq": "Notch3", "protein_names_uniprotkb": "Neurogenic locus notch homolog protein 3", "protein_names_refseq": "neurogenic locus notch homolog protein 3 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100753340)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 148 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) and transcript sequence (IACG01061957.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027275284.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0019899 enzyme binding;GO:0042802 identical protein binding;GO:0005509 calcium ion binding;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0014016 neuroblast differentiation;GO:0006351 DNA-templated transcription;GO:0007219 Notch signaling pathway;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0048661 positive regulation of smooth muscle cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QLK9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QMB3-1", "uniprot_id": [ { "id": "A0A8C2QMB3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QMB3", "type": "external" } ], "mass": 41276.0, "length": 358, "protein_name": "Mitogen-activated protein kinase", "gene_name": "Mapk1", "organism": "Hamster", "refseq_name": "mitogen-activated protein kinase 1 isoform X1", "refseq_ac": [ { "id": "XP_007641645", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641645", "type": "external" } ], "gene_names_uniprotkb": "Mapk1", "gene_names_refseq": "Mapk1", "protein_names_uniprotkb": "Mitogen-activated protein kinase; 2.7.11.24", "protein_names_refseq": "mitogen-activated protein kinase 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100759514)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 307 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613919.1) and transcript sequence (IACG01047994.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007641645.1. COMPLETENESS: full length., [RefSeq]; Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0001784 phosphotyrosine residue binding;GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0019902 phosphatase binding;GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005739 mitochondrion;GO:0005769 early endosome;GO:0005794 Golgi apparatus;GO:0005813 centrosome", "go_biological_process": "GO:0072584 caveolin-mediated endocytosis;GO:2000641 regulation of early endosome to late endosome transport;GO:0035094 response to nicotine;GO:0006915 apoptotic process;GO:0042552 myelination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QMB3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QMJ0-1", "uniprot_id": [ { "id": "A0A8C2QMJ0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QMJ0", "type": "external" } ], "mass": 52153.0, "length": 480, "protein_name": "DnaJ homolog subfamily A member 3, mitochondrial", "gene_name": "Dnaja3", "organism": "Hamster", "refseq_name": "dnaJ homolog subfamily A member 3, mitochondrial isoform X1", "refseq_ac": [ { "id": "XP_027279811", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279811", "type": "external" } ], "gene_names_uniprotkb": "Dnaja3", "gene_names_refseq": "Dnaja3", "protein_names_uniprotkb": "DnaJ homolog subfamily A member 3, mitochondrial; DnaJ protein Tid-1; Tumorous imaginal discs protein Tid56 homolog", "protein_names_refseq": "dnaJ homolog subfamily A member 3, mitochondrial isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100774313)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Modulates apoptotic signal transduction or effector structures within the mitochondrial matrix. Affect cytochrome C release from the mitochondria and caspase 3 activation, but not caspase 8 activation. Isoform 1 increases apoptosis triggered by both TNF and the DNA-damaging agent mytomycin C; in sharp contrast, isoform 2 suppresses apoptosis. Can modulate IFN-gamma-mediated transcriptional activity. Isoform 2 may play a role in neuromuscular junction development as an effector of the MUSK signaling pathway., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0019901 protein kinase binding;GO:0051082 unfolded protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005884 actin filament;GO:0031594 neuromuscular junction;GO:0042645 mitochondrial nucleoid", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0007528 neuromuscular junction development;GO:0008285 negative regulation of cell population proliferation;GO:0043066 negative regulation of apoptotic process;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QMJ0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QMP3-1", "uniprot_id": [ { "id": "A0A8C2QMP3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QMP3", "type": "external" } ], "mass": 83339.0, "length": 749, "protein_name": "Dynamin-1-like protein", "gene_name": "Dnm1l", "organism": "Hamster", "refseq_name": "dynamin-1-like protein isoform X1", "refseq_ac": [ { "id": "XP_007651836", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651836", "type": "external" } ], "gene_names_uniprotkb": "Dnm1l", "gene_names_refseq": "Dnm1l", "protein_names_uniprotkb": "Dynamin-1-like protein; 3.6.5.5; Dynamin-like protein", "protein_names_refseq": "dynamin-1-like protein isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100750819)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 271 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615870.1) and transcript sequence (IACG01003023.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007651836.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0008017 microtubule binding;GO:0042803 protein homodimerization activity;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0099073 mitochondrion-derived vesicle;GO:0005741 mitochondrial outer membrane;GO:0005777 peroxisome;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0090149 mitochondrial membrane fission;GO:1900063 regulation of peroxisome organization;GO:0006897 endocytosis;GO:0016559 peroxisome fission;GO:0051259 protein complex oligomerization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QMP3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QMZ6-1", "uniprot_id": [ { "id": "A0A8C2QMZ6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QMZ6", "type": "external" } ], "mass": 313190.0, "length": 2860, "protein_name": "Adenomatous polyposis coli protein", "gene_name": "Apc", "organism": "Hamster", "refseq_name": "adenomatous polyposis coli protein isoform X2", "refseq_ac": [ { "id": "XP_027256499", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256499", "type": "external" } ], "gene_names_uniprotkb": "Apc", "gene_names_refseq": "Apc", "protein_names_uniprotkb": "Adenomatous polyposis coli protein", "protein_names_refseq": "adenomatous polyposis coli protein isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100750563)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Associates with both microtubules and actin filaments, components of the cytoskeleton. Plays a role in mediating the organization of F-actin into ordered bundles. Functions downstream of Rho GTPases and DIAPH1 to selectively stabilize microtubules. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0031625 ubiquitin protein ligase binding;GO:0008013 beta-catenin binding;GO:0019887 protein kinase regulator activity;GO:0045295 gamma-catenin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0005912 adherens junction;GO:0005923 bicellular tight junction;GO:0030027 lamellipodium", "go_biological_process": "GO:0001708 cell fate specification;GO:0007399 nervous system development;GO:0008285 negative regulation of cell population proliferation;GO:0016477 cell migration;GO:0090090 negative regulation of canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QMZ6-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QN62-1", "uniprot_id": [ { "id": "A0A8C2QN62_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QN62", "type": "external" } ], "mass": 50660.0, "length": 442, "protein_name": "Transforming growth factor beta", "gene_name": "Tgfb2", "organism": "Hamster", "refseq_name": "transforming growth factor beta-2 proprotein isoform X1", "refseq_ac": [ { "id": "XP_003495021", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495021", "type": "external" } ], "gene_names_uniprotkb": "Tgfb2", "gene_names_refseq": "Tgfb2", "protein_names_uniprotkb": "Transforming growth factor beta", "protein_names_refseq": "transforming growth factor beta-2 proprotein isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100774918)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613581.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Multifunctional protein that regulates various processes such as angiogenesis and heart development. Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains remain non-covalently linked rendering TGF-beta-2 inactive during storage in extracellular matrix. At the same time, LAP chain interacts with 'milieu molecules', such as LTBP1 and LRRC32/GARP, that control activation of TGF-beta-2 and maintain it in a latent state during storage in extracellular milieus. Once activated following release of LAP, TGF-beta-2 acts by binding to TGF-beta receptors (TGFBR1 and TGFBR2), which transduce signal., [UniProtKB, UniProtKB, UniProtKB]; Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively., [UniProtKB, UniProtKB, UniProtKB]; Required to maintain the Transforming growth factor beta-2 (TGF-beta-2) chain in a latent state during storage in extracellular matrix. Associates non-covalently with TGF-beta-2 and regulates its activation via interaction with 'milieu molecules', such as LTBP1 and LRRC32/GARP, that control activation of TGF-beta-2., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0034714 type III transforming growth factor beta receptor binding;GO:0042803 protein homodimerization activity;GO:0001540 amyloid-beta binding;GO:0005125 cytokine activity;GO:0008083 growth factor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005768 endosome;GO:0030424 axon;GO:0031012 extracellular matrix;GO:0043025 neuronal cell body", "go_biological_process": "GO:1904888 cranial skeletal system development;GO:0046580 negative regulation of Ras protein signal transduction;GO:1902256 regulation of apoptotic process involved in outflow tract morphogenesis;GO:1903701 substantia propria of cornea development;GO:1904238 pericyte cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QN62-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QNR4-1", "uniprot_id": [ { "id": "A0A8C2QNR4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QNR4", "type": "external" } ], "mass": 71248.0, "length": 646, "protein_name": "Arachidonate--CoA ligase", "gene_name": "Slc27a1", "organism": "Hamster", "refseq_name": "long-chain fatty acid transport protein 1 isoform X2", "refseq_ac": [ { "id": "XP_027250590", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250590", "type": "external" } ], "gene_names_uniprotkb": "Slc27a1", "gene_names_refseq": "Slc27a1", "protein_names_uniprotkb": "Arachidonate--CoA ligase; 6.2.1.15; 6.2.1.3; Long-chain-fatty-acid--CoA ligase", "protein_names_refseq": "long-chain fatty acid transport protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774950)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.3", "type": "external" }, { "id": "6.2.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.15", "type": "external" }, { "id": "6.2.1.76", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.76", "type": "external" } ], "go_molecular_function": "GO:0005324 long-chain fatty acid transmembrane transporter activity;GO:0042802 identical protein binding;GO:0000166 nucleotide binding;GO:0031957 very long-chain fatty acid-CoA ligase activity;GO:0047676 arachidonate-CoA ligase activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005789 endoplasmic reticulum membrane;GO:0009925 basal plasma membrane", "go_biological_process": "GO:1990379 lipid transport across blood-brain barrier;GO:0044381 glucose import in response to insulin stimulus;GO:0001579 medium-chain fatty acid transport;GO:0015911 long-chain fatty acid import across plasma membrane;GO:0010867 positive regulation of triglyceride biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QNR4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QPM9-1", "uniprot_id": [ { "id": "A0A8C2QPM9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QPM9", "type": "external" } ], "mass": 104524.0, "length": 934, "protein_name": "DNA mismatch repair protein", "gene_name": "Msh2", "organism": "Hamster", "refseq_name": "DNA mismatch repair protein Msh2 isoform X2", "refseq_ac": [ { "id": "XP_027273794", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273794", "type": "external" } ], "gene_names_uniprotkb": "Msh2", "gene_names_refseq": "Msh2", "protein_names_uniprotkb": "DNA mismatch repair protein", "protein_names_refseq": "DNA mismatch repair protein Msh2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100768127)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the post-replicative DNA mismatch repair system (MMR)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0032357 oxidized purine DNA binding;GO:0032142 single guanine insertion binding;GO:0032143 single thymine insertion binding;GO:0032181 dinucleotide repeat insertion binding;GO:0000287 magnesium ion binding", "go_cellular_component": "GO:0032301 MutSalpha complex;GO:0005654 nucleoplasm;GO:0005694 chromosome;GO:0032302 MutSbeta complex", "go_biological_process": "GO:0006312 mitotic recombination;GO:0006298 mismatch repair;GO:0048304 positive regulation of isotype switching to IgG isotypes;GO:0045910 negative regulation of DNA recombination;GO:0043570 maintenance of DNA repeat elements", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QPM9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7J1E6-1", "uniprot_id": [ { "id": "A0A9J7J1E6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7J1E6", "type": "external" } ], "mass": 878319.0, "length": 7757, "protein_name": "Dystonin", "gene_name": "Dst", "organism": "Hamster", "refseq_name": "dystonin isoform X12", "refseq_ac": [ { "id": "XP_027242707", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027242707", "type": "external" } ], "gene_names_uniprotkb": "Dst", "gene_names_refseq": "Dst", "protein_names_uniprotkb": "Dystonin; Bullous pemphigoid antigen 1; Dystonia musculorum protein; Hemidesmosomal plaque protein", "protein_names_refseq": "dystonin isoform X12", "tax_id": 10029, "disease": "", "pathway": " (cge:100773919)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hemidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional mesh. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport. Mediates docking of the dynein/dynactin motor complex to vesicle cargos for retrograde axonal transport through its interaction with TMEM108 and DCTN1., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Plays a structural role in the assembly of hemidesmosomes of epithelial cells; anchors keratin-containing intermediate filaments to the inner plaque of hemidesmosomes. Required for the regulation of keratinocyte polarity and motility; mediates integrin ITGB4 regulation of RAC1 activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Required for bundling actin filaments around the nucleus., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding;GO:0005198 structural molecule activity;GO:0003779 actin binding;GO:0042803 protein homodimerization activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005925 focal adhesion;GO:0016020 membrane;GO:0005882 intermediate filament;GO:0030056 hemidesmosome", "go_biological_process": "GO:0042060 wound healing;GO:0031581 hemidesmosome assembly;GO:0045104 intermediate filament cytoskeleton organization;GO:0007155 cell adhesion;GO:0000226 microtubule cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7J1E6-1", "record_type": "protein", "filter_code": "0000000.0000101.000010.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7EX92-1", "uniprot_id": [ { "id": "A0A9J7EX92_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7EX92", "type": "external" } ], "mass": 56741.0, "length": 503, "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "LOC100762189", "organism": "Hamster", "refseq_name": "lanosterol 14-alpha demethylase", "refseq_ac": [ { "id": "XP_027245614", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245614", "type": "external" } ], "gene_names_uniprotkb": "LOC100762189", "gene_names_refseq": "LOC100762189", "protein_names_uniprotkb": "Lanosterol 14-alpha demethylase; 1.14.14.154; CYPLI; Cytochrome P450 51A1; Cytochrome P450-14DM; Cytochrome P450LI", "protein_names_refseq": "lanosterol 14-alpha demethylase", "tax_id": 10029, "disease": "", "pathway": " (cge:100762189)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Sterol 14alpha-demethylase that plays a critical role in the cholesterol biosynthesis pathway, being cholesterol the major sterol component in mammalian membranes as well as a precursor for bile acid and steroid hormone synthesis. Cytochrome P450 monooxygenase that catalyzes the three-step oxidative removal of the 14alpha-methyl group (C-32) of sterols such as lanosterol (lanosta-8,24-dien-3beta-ol) and 24,25-dihydrolanosterol (DHL) in the form of formate, and converts the sterols to 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol and 4,4-dimethyl-8,14-cholestadien-3beta-ol, respectively, which are intermediates of cholesterol biosynthesis. Can also demethylate substrates not intrinsic to mammals, such as eburicol (24-methylene-24,25-dihydrolanosterol), but at a lower rate than DHL., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.14.154", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.154", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0008398 sterol 14-demethylase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006695 cholesterol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7EX92-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F1A6-1", "uniprot_id": [ { "id": "A0A9J7F1A6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F1A6", "type": "external" } ], "mass": 109709.0, "length": 970, "protein_name": "Polycystin-2", "gene_name": "LOC100771469", "organism": "Hamster", "refseq_name": "polycystin-2 isoform X3", "refseq_ac": [ { "id": "XP_027244284", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244284", "type": "external" } ], "gene_names_uniprotkb": "LOC100771469", "gene_names_refseq": "LOC100771469", "protein_names_uniprotkb": "Polycystin-2; Transient receptor potential cation channel subfamily P member 2", "protein_names_refseq": "polycystin-2 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100771469)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051371 muscle alpha-actinin binding;GO:0005102 signaling receptor binding;GO:0005509 calcium ion binding;GO:0005245 voltage-gated calcium channel activity;GO:0005248 voltage-gated sodium channel activity", "go_cellular_component": "GO:0045180 basal cortex;GO:0002133 polycystin complex;GO:0016323 basolateral plasma membrane;GO:0005789 endoplasmic reticulum membrane;GO:0030659 cytoplasmic vesicle membrane", "go_biological_process": "GO:0001889 liver development;GO:0007507 heart development;GO:0045429 positive regulation of nitric oxide biosynthetic process;GO:0001822 kidney development;GO:0051209 release of sequestered calcium ion into cytosol", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F1A6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F4Y1-1", "uniprot_id": [ { "id": "A0A9J7F4Y1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F4Y1", "type": "external" } ], "mass": 83041.0, "length": 731, "protein_name": "Diacylglycerol kinase", "gene_name": "Dgka", "organism": "Hamster", "refseq_name": "diacylglycerol kinase alpha isoform X1", "refseq_ac": [ { "id": "XP_003506247", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506247", "type": "external" } ], "gene_names_uniprotkb": "Dgka", "gene_names_refseq": "Dgka", "protein_names_uniprotkb": "Diacylglycerol kinase; 2.7.1.107; DAG kinase", "protein_names_refseq": "diacylglycerol kinase alpha isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100769779)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614217.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes. Also plays an important role in the biosynthesis of complex lipids. Can also phosphorylate 1-alkyl-2-acylglycerol in vitro as efficiently as diacylglycerol provided it contains an arachidonoyl group. Also involved in the production of alkyl-lysophosphatidic acid, another bioactive lipid, through the phosphorylation of 1-alkyl-2-acetyl glycerol., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.107", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.107", "type": "external" }, { "id": "2.7.1.94", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.94", "type": "external" }, { "id": "2.7.1.138", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.138", "type": "external" } ], "go_molecular_function": "GO:0004143 ATP-dependent diacylglycerol kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0005509 calcium ion binding;GO:0047649 alkylglycerol kinase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F4Y1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F8T9-1", "uniprot_id": [ { "id": "A0A9J7F8T9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F8T9", "type": "external" } ], "mass": 288724.0, "length": 2549, "protein_name": "Serine/threonine-protein kinase mTOR", "gene_name": "Mtor", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase mTOR", "refseq_ac": [ { "id": "XP_027254008", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254008", "type": "external" } ], "gene_names_uniprotkb": "Mtor", "gene_names_refseq": "Mtor", "protein_names_uniprotkb": "Serine/threonine-protein kinase mTOR; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase mTOR", "tax_id": 10029, "disease": "", "pathway": " (cge:100755421)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005741 mitochondrial outer membrane;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005765 lysosomal membrane", "go_biological_process": "GO:0051896 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0048714 positive regulation of oligodendrocyte differentiation;GO:0019216 regulation of lipid metabolic process;GO:0050795 regulation of behavior;GO:0038202 TORC1 signaling", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F8T9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FB01-1", "uniprot_id": [ { "id": "A0A9J7FB01_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FB01", "type": "external" } ], "mass": 45289.0, "length": 411, "protein_name": "Hedgehog protein", "gene_name": "Ihh", "organism": "Hamster", "refseq_name": "indian hedgehog protein isoform X2", "refseq_ac": [ { "id": "XP_027251783", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251783", "type": "external" } ], "gene_names_uniprotkb": "Ihh", "gene_names_refseq": "Ihh", "protein_names_uniprotkb": "Hedgehog protein", "protein_names_refseq": "indian hedgehog protein isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774896)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 10% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product., [UniProtKB, UniProtKB]; The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0016740 transferase activity;GO:0008233 peptidase activity;GO:0005113 patched binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0003006 developmental process involved in reproduction;GO:0001708 cell fate specification;GO:0010720 positive regulation of cell development;GO:0007267 cell-cell signaling;GO:0008284 positive regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FB01-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FDL4-1", "uniprot_id": [ { "id": "A0A9J7FDL4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FDL4", "type": "external" } ], "mass": 59931.0, "length": 534, "protein_name": "Lysophosphatidylcholine acyltransferase 1", "gene_name": "LOC103161085", "organism": "Hamster", "refseq_name": "lysophosphatidylcholine acyltransferase 1 isoform X2", "refseq_ac": [ { "id": "XP_027255932", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255932", "type": "external" } ], "gene_names_uniprotkb": "LOC103161085", "gene_names_refseq": "LOC103161085", "protein_names_uniprotkb": "Lysophosphatidylcholine acyltransferase 1; 1-acylglycerol-3-phosphate O-acyltransferase; 1-acylglycerophosphocholine O-acyltransferase; 1-alkenylglycerophosphocholine O-acyltransferase; 1-alkylglycerophosphocholine O-acetyltransferase; 2.3.1.23; 2.3.1.25; 2.3.1.51; 2.3.1.67; Acetyl-CoA:lyso-platelet-activating factor acetyltransferase; Acyltransferase-like 2", "protein_names_refseq": "lysophosphatidylcholine acyltransferase 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:103161085)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" }, { "id": "1.11.1.27", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.27", "type": "external" }, { "id": "2.3.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.15", "type": "external" }, { "id": "2.3.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.23", "type": "external" }, { "id": "2.3.1.67", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.67", "type": "external" }, { "id": "2.3.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.25", "type": "external" }, { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" } ], "go_molecular_function": "GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0005509 calcium ion binding;GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity;GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity;GO:0047159 plasmalogen synthase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005811 lipid droplet;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0008654 phospholipid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FDL4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FGN0-1", "uniprot_id": [ { "id": "A0A9J7FGN0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FGN0", "type": "external" } ], "mass": 57162.0, "length": 513, "protein_name": "Alanine--glyoxylate aminotransferase 2, mitochondrial", "gene_name": "Agxt2", "organism": "Hamster", "refseq_name": "alanine--glyoxylate aminotransferase 2, mitochondrial isoform X1", "refseq_ac": [ { "id": "XP_027257087", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257087", "type": "external" } ], "gene_names_uniprotkb": "Agxt2", "gene_names_refseq": "Agxt2", "protein_names_uniprotkb": "Alanine--glyoxylate aminotransferase 2, mitochondrial; (R)-3-amino-2-methylpropionate--pyruvate transaminase; 2.6.1.18; 2.6.1.40; 2.6.1.44; Beta-ALAAT II; Beta-alanine-pyruvate aminotransferase; D-3-aminoisobutyrate-pyruvate aminotransferase; D-AIBAT; D-beta-aminoisobutyrate-pyruvate aminotransferase", "protein_names_refseq": "alanine--glyoxylate aminotransferase 2, mitochondrial isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100759906)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Multifunctional aminotransferase with a broad substrate specificity. Catalyzes the conversion of glyoxylate to glycine using alanine as the amino donor. Catalyzes metabolism of not L- but the D-isomer of D-beta-aminoisobutyric acid to generate 2-methyl-3-oxopropanoate and alanine. Catalyzes the transfer of the amino group from beta-alanine to pyruvate to yield L-alanine and 3-oxopropanoate. Can metabolize NG-monomethyl-L-arginine (NMMA), asymmetric NG,NG-dimethyl-L-arginine (ADMA) and symmetric NG,N'G-dimethyl-L-arginine (SDMA). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.6.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.40", "type": "external" }, { "id": "2.6.1.44", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.44", "type": "external" }, { "id": "2.6.1.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.18", "type": "external" }, { "id": "2.6.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.51", "type": "external" } ], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0008453 alanine-glyoxylate transaminase activity;GO:0047305 (R)-3-amino-2-methylpropionate-pyruvate transaminase activity;GO:0016223 beta-alanine:pyruvate transaminase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0009436 glyoxylate catabolic process;GO:0019481 L-alanine catabolic process, by transamination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FGN0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JGR2-1", "uniprot_id": [ { "id": "A0A9J7JGR2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JGR2", "type": "external" } ], "mass": 158436.0, "length": 1354, "protein_name": "Rho-associated protein kinase", "gene_name": "Rock1", "organism": "Hamster", "refseq_name": "rho-associated protein kinase 1 isoform X3", "refseq_ac": [ { "id": "XP_027259436", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259436", "type": "external" } ], "gene_names_uniprotkb": "Rock1", "gene_names_refseq": "Rock1", "protein_names_uniprotkb": "Rho-associated protein kinase", "protein_names_refseq": "rho-associated protein kinase 1 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100770074)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0072518 Rho-dependent protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005886 plasma membrane;GO:0030027 lamellipodium;GO:0005814 centriole;GO:0001726 ruffle", "go_biological_process": "GO:0071559 response to transforming growth factor beta;GO:0006915 apoptotic process;GO:0007266 Rho protein signal transduction;GO:0031032 actomyosin structure organization;GO:0048598 embryonic morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JGR2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FGH3-1", "uniprot_id": [ { "id": "A0A9J7FGH3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FGH3", "type": "external" } ], "mass": 89776.0, "length": 807, "protein_name": "85/88 kDa calcium-independent phospholipase A2", "gene_name": "Pla2g6", "organism": "Hamster", "refseq_name": "85/88 kDa calcium-independent phospholipase A2 isoform X2", "refseq_ac": [ { "id": "XP_027241681", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027241681", "type": "external" } ], "gene_names_uniprotkb": "Pla2g6", "gene_names_refseq": "Pla2g6", "protein_names_uniprotkb": "85/88 kDa calcium-independent phospholipase A2; 2-lysophosphatidylcholine acylhydrolase; 3.1.1.4; 3.1.1.5; 3.1.2.2; Group VI phospholipase A2; Intracellular membrane-associated calcium-independent phospholipase A2 beta; Palmitoyl-CoA hydrolase; Patatin-like phospholipase domain-containing protein 9", "protein_names_refseq": "85/88 kDa calcium-independent phospholipase A2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100751421)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 347 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003617169.1) and transcript sequence (IACG01088123.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027241681.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "3.1.2.22", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.22", "type": "external" }, { "id": "1.11.1.27", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.27", "type": "external" }, { "id": "3.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32", "type": "external" }, { "id": "3.1.1.47", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.47", "type": "external" }, { "id": "3.1.2.14", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.14", "type": "external" }, { "id": "3.1.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.27", "type": "external" }, { "id": "3.1.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.1", "type": "external" }, { "id": "3.1.2.11", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.11", "type": "external" }, { "id": "3.1.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.3", "type": "external" }, { "id": "3.1.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.5", "type": "external" }, { "id": "3.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.-", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" }, { "id": "3.5.2.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.2.6", "type": "external" } ], "go_molecular_function": "GO:0042802 identical protein binding;GO:0017171 serine hydrolase activity;GO:0004622 phosphatidylcholine lysophospholipase activity;GO:0004623 phospholipase A2 activity;GO:0052816 long-chain fatty acyl-CoA hydrolase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005739 mitochondrion;GO:0005886 plasma membrane;GO:0031143 pseudopodium", "go_biological_process": "GO:0034638 phosphatidylcholine catabolic process;GO:0019731 antibacterial humoral response;GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0035965 cardiolipin acyl-chain remodeling;GO:2000304 positive regulation of ceramide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FGH3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FHG9-1", "uniprot_id": [ { "id": "A0A9J7FHG9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FHG9", "type": "external" } ], "mass": 52251.0, "length": 472, "protein_name": "E3 ubiquitin-protein ligase parkin", "gene_name": "Prkn", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase parkin isoform X2", "refseq_ac": [ { "id": "XP_027256904", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256904", "type": "external" } ], "gene_names_uniprotkb": "Prkn", "gene_names_refseq": "Prkn", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase parkin; 2.3.2.31", "protein_names_refseq": "E3 ubiquitin-protein ligase parkin isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100764359)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0031593 polyubiquitin modification-dependent protein binding;GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005741 mitochondrial outer membrane;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0014069 postsynaptic density", "go_biological_process": "GO:0070585 protein localization to mitochondrion;GO:0006351 DNA-templated transcription;GO:0051881 regulation of mitochondrial membrane potential;GO:0016567 protein ubiquitination;GO:0050804 modulation of chemical synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FHG9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FIT0-1", "uniprot_id": [ { "id": "A0A9J7FIT0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FIT0", "type": "external" } ], "mass": 122911.0, "length": 1101, "protein_name": "Platelet-derived growth factor receptor beta", "gene_name": "Pdgfrb", "organism": "Hamster", "refseq_name": "platelet-derived growth factor receptor beta isoform X2", "refseq_ac": [ { "id": "XP_027258603", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258603", "type": "external" } ], "gene_names_uniprotkb": "Pdgfrb", "gene_names_refseq": "Pdgfrb", "protein_names_uniprotkb": "Platelet-derived growth factor receptor beta; 2.7.10.1; Beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; PDGF-R-beta; PDGFR-beta", "protein_names_refseq": "platelet-derived growth factor receptor beta isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100764374)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0048407 platelet-derived growth factor binding;GO:0005019 platelet-derived growth factor beta-receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex;GO:0031410 cytoplasmic vesicle;GO:0043202 lysosomal lumen", "go_biological_process": "GO:0001525 angiogenesis;GO:0008284 positive regulation of cell population proliferation;GO:0042542 response to hydrogen peroxide;GO:0060326 cell chemotaxis;GO:1902533 positive regulation of intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FIT0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FJS1-1", "uniprot_id": [ { "id": "A0A9J7FJS1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FJS1", "type": "external" } ], "mass": 99196.0, "length": 874, "protein_name": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 3", "gene_name": "Enpp3", "organism": "Hamster", "refseq_name": "ectonucleotide pyrophosphatase/phosphodiesterase family member 3 isoform X3", "refseq_ac": [ { "id": "XP_027258713", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258713", "type": "external" } ], "gene_names_uniprotkb": "Enpp3", "gene_names_refseq": "Enpp3", "protein_names_uniprotkb": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 3; 3.1.4.1; 3.6.1.9; Alkaline phosphodiesterase I; Dinucleoside polyphosphatase; Nucleotide diphosphatase; Nucleotide pyrophosphatase; Phosphodiesterase I beta; Phosphodiesterase I/nucleotide pyrophosphatase 3", "protein_names_refseq": "ectonucleotide pyrophosphatase/phosphodiesterase family member 3 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100751104)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.9", "type": "external" }, { "id": "3.6.1.68", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.68", "type": "external" }, { "id": "3.6.1.76", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.76", "type": "external" }, { "id": "3.1.3.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.5", "type": "external" }, { "id": "3.1.3.91", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.91", "type": "external" }, { "id": "3.1.3.89", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.89", "type": "external" }, { "id": "3.1.3.99", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.99", "type": "external" }, { "id": "3.1.3.35", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.35", "type": "external" }, { "id": "3.6.1.29", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.29", "type": "external" }, { "id": "3.6.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.17", "type": "external" }, { "id": "3.1.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.1", "type": "external" }, { "id": "2.7.7.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.51", "type": "external" }, { "id": "3.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.2.1", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "2.7.1.77", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.77", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0003676 nucleic acid binding;GO:0004528 phosphodiesterase I activity;GO:0047429 nucleoside triphosphate diphosphatase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0009986 cell surface;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0009143 nucleoside triphosphate catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FJS1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FKB3-1", "uniprot_id": [ { "id": "A0A9J7FKB3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FKB3", "type": "external" } ], "mass": 72522.0, "length": 651, "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN", "gene_name": "Pten", "organism": "Hamster", "refseq_name": "phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X3", "refseq_ac": [ { "id": "XP_027262192", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262192", "type": "external" } ], "gene_names_uniprotkb": "Pten", "gene_names_refseq": "Pten", "protein_names_uniprotkb": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; 3.1.3.16; 3.1.3.48; 3.1.3.67; Inositol polyphosphate 3-phosphatase; Phosphatase and tensin homolog", "protein_names_refseq": "phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100764294)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also functions as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring of PtdIns(3,4,5)P3/phosphatidylinositol 3,4,5-trisphosphate, PtdIns(3,4)P2/phosphatidylinositol 3,4-diphosphate and PtdIns3P/phosphatidylinositol 3-phosphate with a preference for PtdIns(3,4,5)P3., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.52", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.52", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21", "type": "external" }, { "id": "3.1.3.74", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.74", "type": "external" }, { "id": "3.1.3.62", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.62", "type": "external" }, { "id": "3.1.3.80", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.80", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.86", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.86", "type": "external" }, { "id": "3.1.3.95", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.95", "type": "external" }, { "id": "3.1.3.36", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.36", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" } ], "go_molecular_function": "GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity;GO:0019899 enzyme binding;GO:0004722 protein serine/threonine phosphatase activity;GO:0004725 protein tyrosine phosphatase activity;GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0014069 postsynaptic density;GO:0043197 dendritic spine;GO:0016605 PML body", "go_biological_process": "GO:0051896 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0007399 nervous system development;GO:0006915 apoptotic process;GO:0045595 regulation of cell differentiation;GO:0043491 phosphatidylinositol 3-kinase/protein kinase B signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FKB3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FN52-1", "uniprot_id": [ { "id": "A0A9J7FN52_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FN52", "type": "external" } ], "mass": 40620.0, "length": 351, "protein_name": "cAMP-dependent protein kinase catalytic subunit alpha", "gene_name": "Prkaca", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Prkaca", "gene_names_refseq": "", "protein_names_uniprotkb": "cAMP-dependent protein kinase catalytic subunit alpha; 2.7.11.11", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100768997)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0019901 protein kinase binding;GO:0019904 protein domain specific binding;GO:0030145 manganese ion binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005739 mitochondrion;GO:0005811 lipid droplet;GO:0005813 centrosome;GO:0005829 cytosol", "go_biological_process": "GO:1904539 negative regulation of glycolytic process through fructose-6-phosphate;GO:0006397 mRNA processing;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0010898 positive regulation of triglyceride catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FN52-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FQ70-1", "uniprot_id": [ { "id": "A0A9J7FQ70_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FQ70", "type": "external" } ], "mass": 53980.0, "length": 481, "protein_name": "Triacylglycerol lipase", "gene_name": "LOC100758718", "organism": "Hamster", "refseq_name": "pancreatic lipase-related protein 2 isoform X2", "refseq_ac": [ { "id": "XP_027262694", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262694", "type": "external" } ], "gene_names_uniprotkb": "LOC100758718", "gene_names_refseq": "LOC100758718", "protein_names_uniprotkb": "Triacylglycerol lipase; 3.1.1.3; Pancreatic lipase", "protein_names_refseq": "pancreatic lipase-related protein 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100758718)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.116", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.116", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "3.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.-", "type": "external" }, { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "3.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32", "type": "external" }, { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" }, { "id": "3.1.1.34", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.34", "type": "external" }, { "id": "3.1.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.23", "type": "external" }, { "id": "3.1.1.79", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.79", "type": "external" }, { "id": "3.1.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.6", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004620 phospholipase activity;GO:0004465 lipoprotein lipase activity;GO:0047714 galactolipase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0043005 neuron projection;GO:0042589 zymogen granule membrane", "go_biological_process": "GO:0009395 phospholipid catabolic process;GO:0019433 triglyceride catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FQ70-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K6N5-1", "uniprot_id": [ { "id": "A0A9J7K6N5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K6N5", "type": "external" } ], "mass": 87473.0, "length": 795, "protein_name": "Cyclic GMP-AMP synthase", "gene_name": "LOC100754516", "organism": "Hamster", "refseq_name": "cyclic GMP-AMP synthase isoform X1", "refseq_ac": [ { "id": "XP_016831481", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831481", "type": "external" } ], "gene_names_uniprotkb": "LOC100754516", "gene_names_refseq": "LOC100754516", "protein_names_uniprotkb": "Cyclic GMP-AMP synthase; 2'3'-cGAMP synthase; 2.7.7.86; Mab-21 domain-containing protein 1", "protein_names_refseq": "cyclic GMP-AMP synthase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100754516)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613946.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.86", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.86", "type": "external" } ], "go_molecular_function": "GO:0061501 2',3'-cyclic GMP-AMP synthase activity;GO:0003682 chromatin binding;GO:0003690 double-stranded DNA binding;GO:0005524 ATP binding;GO:0005525 GTP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0035861 site of double-strand break;GO:0005886 plasma membrane", "go_biological_process": "GO:0071360 cellular response to exogenous dsRNA;GO:2000042 negative regulation of double-strand break repair via homologous recombination;GO:0006974 DNA damage response;GO:0002230 positive regulation of defense response to virus by host;GO:0002218 activation of innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K6N5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FX08-1", "uniprot_id": [ { "id": "A0A9J7FX08_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FX08", "type": "external" } ], "mass": 24894.0, "length": 215, "protein_name": "High mobility group protein B1", "gene_name": "Hmgb1", "organism": "Hamster", "refseq_name": "high mobility group protein B1 isoform X2", "refseq_ac": [ { "id": "XP_027269518", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269518", "type": "external" } ], "gene_names_uniprotkb": "Hmgb1", "gene_names_refseq": "Hmgb1", "protein_names_uniprotkb": "High mobility group protein B1; High mobility group protein 1", "protein_names_refseq": "high mobility group protein B1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754755)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; In the cytoplasm proposed to dissociate the BECN1:BCL2 complex via competitive interaction with BECN1 leading to autophagy activation. Can protect BECN1 and ATG5 from calpain-mediated cleavage and thus proposed to control their proautophagic and proapoptotic functions and to regulate the extent and severity of inflammation-associated cellular injury. In myeloid cells has a protective role against endotoxemia and bacterial infection by promoting autophagy. Involved in endosomal translocation and activation of TLR9 in response to CpG-DNA in macrophages., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008201 heparin binding;GO:0008289 lipid binding;GO:0005125 cytokine activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005634 nucleus;GO:0005768 endosome;GO:0005886 plasma membrane;GO:0005694 chromosome", "go_biological_process": "GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006935 chemotaxis;GO:0006954 inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FX08-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G2Q4-1", "uniprot_id": [ { "id": "A0A9J7G2Q4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G2Q4", "type": "external" } ], "mass": 128183.0, "length": 1182, "protein_name": "Tyrosine-protein kinase", "gene_name": "Abl2", "organism": "Hamster", "refseq_name": "tyrosine-protein kinase ABL2 isoform X10", "refseq_ac": [ { "id": "XP_027273107", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273107", "type": "external" } ], "gene_names_uniprotkb": "Abl2", "gene_names_refseq": "Abl2", "protein_names_uniprotkb": "Tyrosine-protein kinase; 2.7.10.2", "protein_names_refseq": "tyrosine-protein kinase ABL2 isoform X10", "tax_id": 10029, "disease": "", "pathway": " (cge:100772469)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0030145 manganese ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0015629 actin cytoskeleton", "go_biological_process": "GO:1902532 negative regulation of intracellular signal transduction;GO:1903905 positive regulation of establishment of T cell polarity;GO:0010976 positive regulation of neuron projection development;GO:0050885 neuromuscular process controlling balance;GO:0070374 positive regulation of ERK1 and ERK2 cascade", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G2Q4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G1I2-1", "uniprot_id": [ { "id": "A0A9J7G1I2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G1I2", "type": "external" } ], "mass": 217350.0, "length": 1926, "protein_name": "Lactase/phlorizin hydrolase", "gene_name": "Lct", "organism": "Hamster", "refseq_name": "lactase-phlorizin hydrolase isoform X1", "refseq_ac": [ { "id": "XP_027273540", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273540", "type": "external" } ], "gene_names_uniprotkb": "Lct", "gene_names_refseq": "Lct", "protein_names_uniprotkb": "Lactase/phlorizin hydrolase; 3.2.1.108; 3.2.1.62; Lactase/glycosylceramidase", "protein_names_refseq": "lactase-phlorizin hydrolase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100766856)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Broad specificity glycosidase of the intestinal brush border membrane that hydrolyzes lactose, the main sugar in mammalian milk, to produce D-glucose and D-galactose. The mature protein is composed of two domains that catalyze the hydrolysis of beta-glucopyranosides and beta-galactopyranosides, with a preference for hydrophilic aglycones (in lactose and cellobiose) for one domain and hydrophobic aglycones (in phlorizin and glycosylceramides) for the other., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.2.1.108", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.108", "type": "external" }, { "id": "3.2.1.62", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.62", "type": "external" } ], "go_molecular_function": "GO:0000016 lactase activity", "go_cellular_component": "GO:0016324 apical plasma membrane", "go_biological_process": "GO:0005975 carbohydrate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G1I2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G1N7-1", "uniprot_id": [ { "id": "A0A9J7G1N7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G1N7", "type": "external" } ], "mass": 84904.0, "length": 783, "protein_name": "Gephyrin", "gene_name": "LOC100762786", "organism": "Hamster", "refseq_name": "gephyrin isoform X5", "refseq_ac": [ { "id": "XP_027274135", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274135", "type": "external" } ], "gene_names_uniprotkb": "LOC100762786", "gene_names_refseq": "LOC100762786", "protein_names_uniprotkb": "Gephyrin; Domain E; Domain G", "protein_names_refseq": "gephyrin isoform X5", "tax_id": 10029, "disease": "", "pathway": " (cge:100762786)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Also has a catalytic activity and catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules. Acts as a major instructive molecule at inhibitory synapses, where it also clusters GABA type A receptors., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.10.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.10.1.1", "type": "external" }, { "id": "2.7.7.75", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.75", "type": "external" } ], "go_molecular_function": "GO:0061598 molybdopterin adenylyltransferase activity;GO:0061599 molybdopterin molybdotransferase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0014069 postsynaptic density;GO:0030425 dendrite;GO:0060077 inhibitory synapse", "go_biological_process": "GO:0072579 glycine receptor clustering;GO:0097112 gamma-aminobutyric acid receptor clustering;GO:0007529 establishment of synaptic specificity at neuromuscular junction;GO:0098970 postsynaptic neurotransmitter receptor diffusion trapping;GO:0006777 Mo-molybdopterin cofactor biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G1N7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G6V0-1", "uniprot_id": [ { "id": "A0A9J7G6V0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G6V0", "type": "external" } ], "mass": 35951.0, "length": 320, "protein_name": "Phospholipid phosphatase 2", "gene_name": "Plpp2", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: phospholipid phosphatase 2", "refseq_ac": [ { "id": "XP_003502642", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502642", "type": "external" } ], "gene_names_uniprotkb": "Plpp2", "gene_names_refseq": "Plpp2", "protein_names_uniprotkb": "Phospholipid phosphatase 2; 3.1.3.4; Lipid phosphate phosphohydrolase 2; PAP2-gamma; Phosphatidate phosphohydrolase type 2c; Phosphatidic acid phosphatase 2c", "protein_names_refseq": "LOW QUALITY PROTEIN: phospholipid phosphatase 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774295)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613904.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_003502642.2. COMPLETENESS: full length., [RefSeq]; Magnesium-independent phospholipid phosphatase that catalyzes the dephosphorylation of a variety of glycerolipid and sphingolipid phosphate esters including phosphatidate/PA, lysophosphatidate/LPA, sphingosine 1-phosphate/S1P and ceramide 1-phosphate/C1P. Has no apparent extracellular phosphatase activity and therefore most probably acts intracellularly. Also acts on N-oleoyl ethanolamine phosphate/N-(9Z-octadecenoyl)-ethanolamine phosphate, a potential physiological compound. Through dephosphorylation of these bioactive lipid mediators produces new bioactive compounds and may regulate signal transduction in different cellular processes. Indirectly regulates, for instance, cell cycle G1/S phase transition through its phospholipid phosphatase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.1.68", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.68", "type": "external" }, { "id": "3.1.3.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.4", "type": "external" }, { "id": "3.1.3.106", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.106", "type": "external" }, { "id": "3.6.1.75", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.75", "type": "external" } ], "go_molecular_function": "GO:0008195 phosphatidate phosphatase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane;GO:0031901 early endosome membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0006644 phospholipid metabolic process;GO:0046839 phospholipid dephosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G6V0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GC40-1", "uniprot_id": [ { "id": "A0A9J7GC40_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GC40", "type": "external" } ], "mass": 124497.0, "length": 1118, "protein_name": "Diacylglycerol kinase", "gene_name": "Dgkz", "organism": "Hamster", "refseq_name": "diacylglycerol kinase zeta isoform X1", "refseq_ac": [ { "id": "XP_027278289", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278289", "type": "external" } ], "gene_names_uniprotkb": "Dgkz", "gene_names_refseq": "Dgkz", "protein_names_uniprotkb": "Diacylglycerol kinase; 2.7.1.107; DAG kinase", "protein_names_refseq": "diacylglycerol kinase zeta isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100751991)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.107", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.107", "type": "external" }, { "id": "2.7.1.94", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.94", "type": "external" }, { "id": "2.7.1.138", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.138", "type": "external" } ], "go_molecular_function": "GO:0004143 ATP-dependent diacylglycerol kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0047649 alkylglycerol kinase activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005634 nucleus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0030027 lamellipodium", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GC40-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G7X5-1", "uniprot_id": [ { "id": "A0A9J7G7X5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G7X5", "type": "external" } ], "mass": 77182.0, "length": 686, "protein_name": "Protein-glutamine gamma-glutamyltransferase 2", "gene_name": "Tgm2", "organism": "Hamster", "refseq_name": "protein-glutamine gamma-glutamyltransferase 2", "refseq_ac": [ { "id": "XP_027277053", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277053", "type": "external" } ], "gene_names_uniprotkb": "Tgm2", "gene_names_refseq": "Tgm2", "protein_names_uniprotkb": "Protein-glutamine gamma-glutamyltransferase 2; 2.3.2.13; 3.5.1.44; Isopeptidase TGM2; Protein-glutamine deamidase TGM2; Protein-glutamine dopaminyltransferase TGM2; Protein-glutamine histaminyltransferase TGM2; Protein-glutamine noradrenalinyltransferase TGM2; Protein-glutamine serotonyltransferase TGM2; Tissue transglutaminase; Transglutaminase II; Transglutaminase-2", "protein_names_refseq": "protein-glutamine gamma-glutamyltransferase 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100759289)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.13", "type": "external" }, { "id": "3.5.1.44", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.44", "type": "external" } ], "go_molecular_function": "GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0008233 peptidase activity;GO:0003810 protein-glutamine gamma-glutamyltransferase activity;GO:0050568 protein-glutamine glutaminase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005694 chromosome", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G7X5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G8F0-1", "uniprot_id": [ { "id": "A0A9J7G8F0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G8F0", "type": "external" } ], "mass": 71364.0, "length": 654, "protein_name": "Carboxylic ester hydrolase", "gene_name": "Cel", "organism": "Hamster", "refseq_name": "bile salt-activated lipase", "refseq_ac": [ { "id": "XP_027278863", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278863", "type": "external" } ], "gene_names_uniprotkb": "Cel", "gene_names_refseq": "Cel", "protein_names_uniprotkb": "Carboxylic ester hydrolase; 3.1.1.-", "protein_names_refseq": "bile salt-activated lipase", "tax_id": 10029, "disease": "", "pathway": " (cge:100771549)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 6, "predicted_n_glycosites": 0, "predicted_o_glycosites": 6, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "3.1.2.22", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.22", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "3.1.1.116", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.116", "type": "external" }, { "id": "3.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.-", "type": "external" }, { "id": "3.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32", "type": "external" }, { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" }, { "id": "3.1.1.34", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.34", "type": "external" }, { "id": "3.1.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.23", "type": "external" }, { "id": "3.1.1.79", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.79", "type": "external" }, { "id": "3.1.1.71", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.71", "type": "external" }, { "id": "3.1.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.6", "type": "external" } ], "go_molecular_function": "GO:0004771 sterol ester esterase activity;GO:0004806 triacylglycerol lipase activity;GO:0008126 acetylesterase activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0016042 lipid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G8F0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G9Q8-1", "uniprot_id": [ { "id": "A0A9J7G9Q8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G9Q8", "type": "external" } ], "mass": 145686.0, "length": 1300, "protein_name": "Phospholipase B1, membrane-associated", "gene_name": "Plb1", "organism": "Hamster", "refseq_name": "phospholipase B1, membrane-associated", "refseq_ac": [ { "id": "XP_027280224", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280224", "type": "external" } ], "gene_names_uniprotkb": "Plb1", "gene_names_refseq": "Plb1", "protein_names_uniprotkb": "Phospholipase B1, membrane-associated; 3.1.1.3; 3.1.1.4; 3.1.1.5; Lysophospholipase; Phospholipase A2; Phospholipase B/lipase; Triacylglycerol lipase", "protein_names_refseq": "phospholipase B1, membrane-associated", "tax_id": 10029, "disease": "", "pathway": " (cge:100761810)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027280224.1. COMPLETENESS: full length., [RefSeq]; Calcium-independent membrane-associated phospholipase that catalyzes complete diacylation of phospholipids by hydrolyzing both sn-1 and sn-2 fatty acyl chains attached to the glycerol backbone (phospholipase B activity). Has dual phospholipase and lysophospholipase activities toward diacylphospholipids. Preferentially cleaves sn-2 ester bonds over sn-1 bonds. Acts as a lipase toward glycerolipid substrates. Hydrolyzes fatty acyl chains of diacylglycerols with preference for the sn-2 position and of triacylglycerols with not positional selectivity. May also hydrolyze long chain retinyl esters such as retinyl palmitate. May contribute to digestion of dietary phospholipids, glycerolipids and retinoids, facilitating lipid absorption at the brush border., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "3.1.2.22", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.22", "type": "external" }, { "id": "1.11.1.27", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.27", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "3.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32", "type": "external" }, { "id": "3.1.1.116", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.116", "type": "external" }, { "id": "3.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.-", "type": "external" }, { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" }, { "id": "3.1.1.34", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.34", "type": "external" }, { "id": "3.1.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.23", "type": "external" }, { "id": "3.1.1.79", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.79", "type": "external" }, { "id": "3.1.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.6", "type": "external" } ], "go_molecular_function": "GO:0004622 phosphatidylcholine lysophospholipase activity;GO:0004623 phospholipase A2 activity;GO:0004806 triacylglycerol lipase activity;GO:0050253 retinyl-palmitate esterase activity", "go_cellular_component": "GO:0031526 brush border membrane", "go_biological_process": "GO:0006644 phospholipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G9Q8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JY99-1", "uniprot_id": [ { "id": "A0A9J7JY99_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JY99", "type": "external" } ], "mass": 66512.0, "length": 614, "protein_name": "Spastin", "gene_name": "Spast", "organism": "Hamster", "refseq_name": "spastin isoform X3", "refseq_ac": [ { "id": "XP_027281889", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281889", "type": "external" } ], "gene_names_uniprotkb": "Spast; SPAST; SPG4", "gene_names_refseq": "Spast", "protein_names_uniprotkb": "Spastin; 5.6.1.1", "protein_names_refseq": "spastin isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100765919)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. It is critical for the biogenesis and maintenance of complex microtubule arrays in axons, spindles and cilia. SPAST is involved in abscission step of cytokinesis and nuclear envelope reassembly during anaphase in cooperation with the ESCRT-III complex. Recruited at the midbody, probably by IST1, and participates in membrane fission during abscission together with the ESCRT-III complex. Recruited to the nuclear membrane by IST1 and mediates microtubule severing, promoting nuclear envelope sealing and mitotic spindle disassembly during late anaphase. Required for membrane traffic from the endoplasmic reticulum (ER) to the Golgi and endosome recycling. Recruited by IST1 to endosomes and regulates early endosomal tubulation and recycling by mediating microtubule severing. Probably plays a role in axon growth and the formation of axonal branches., [UniProtKB, HAMAP, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008568 microtubule severing ATPase activity;GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005768 endosome;GO:0005783 endoplasmic reticulum;GO:0005813 centrosome;GO:0005819 spindle", "go_biological_process": "GO:0051013 microtubule severing;GO:0031117 positive regulation of microtubule depolymerization;GO:0007409 axonogenesis;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0032506 cytokinetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JY99-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GDP4-1", "uniprot_id": [ { "id": "A0A9J7GDP4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GDP4", "type": "external" } ], "mass": 244861.0, "length": 2242, "protein_name": "Multifunctional protein CAD", "gene_name": "Cad", "organism": "Hamster", "refseq_name": "CAD protein isoform X1", "refseq_ac": [ { "id": "XP_027280284", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280284", "type": "external" } ], "gene_names_uniprotkb": "Cad", "gene_names_refseq": "Cad", "protein_names_uniprotkb": "Multifunctional protein CAD; 2.1.3.2; 3.5.1.2; 3.5.2.3; 6.3.4.16; 6.3.5.5; Carbamoyl phosphate synthetase 2-aspartate transcarbamylase-dihydroorotase", "protein_names_refseq": "CAD protein isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100689232)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Multifunctional protein that encodes the first 3 enzymatic activities of the de novo pyrimidine pathway: carbamoylphosphate synthetase (CPSase; EC 6.3.5.5), aspartate transcarbamylase (ATCase; EC 2.1.3.2) and dihydroorotase (DHOase; EC 3.5.2.3). The CPSase-function is accomplished in 2 steps, by a glutamine-dependent amidotransferase activity (GATase) that binds and cleaves glutamine to produce ammonia, followed by an ammonium-dependent carbamoyl phosphate synthetase, which reacts with the ammonia, hydrogencarbonate and ATP to form carbamoyl phosphate. The endogenously produced carbamoyl phosphate is sequestered and channeled to the ATCase active site. ATCase then catalyzes the formation of carbamoyl-L-aspartate from L-aspartate and carbamoyl phosphate. In the last step, DHOase catalyzes the cyclization of carbamoyl aspartate to dihydroorotate., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.5.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.2", "type": "external" }, { "id": "6.3.4.16", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.4.16", "type": "external" }, { "id": "2.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.3.2", "type": "external" }, { "id": "3.5.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.2.3", "type": "external" }, { "id": "6.3.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.5.5", "type": "external" } ], "go_molecular_function": "GO:0004087 carbamoyl-phosphate synthase (ammonia) activity;GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity;GO:0004151 dihydroorotase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0019240 citrulline biosynthetic process;GO:0006541 glutamine metabolic process;GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process;GO:0006228 UTP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GDP4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GE34-1", "uniprot_id": [ { "id": "A0A9J7GE34_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GE34", "type": "external" } ], "mass": 24900.0, "length": 225, "protein_name": "Phosphatidylethanolamine N-methyltransferase", "gene_name": "Pemt", "organism": "Hamster", "refseq_name": "phosphatidylethanolamine N-methyltransferase isoform X1", "refseq_ac": [ { "id": "XP_027283113", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283113", "type": "external" } ], "gene_names_uniprotkb": "Pemt; PEMT", "gene_names_refseq": "Pemt", "protein_names_uniprotkb": "Phosphatidylethanolamine N-methyltransferase; 2.1.1.17; 2.1.1.71; PEAMT; PEMT; PLMT; Phospholipid methyltransferase", "protein_names_refseq": "phosphatidylethanolamine N-methyltransferase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100767954)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the three sequential steps of the methylation pathway for the biosynthesis of phosphatidylcholine, a critical and essential component for membrane structure. Uses S-adenosylmethionine (S-adenosyl-L-methionine, SAM or AdoMet) as the methyl group donor for the methylation of phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to phosphatidylmonomethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine, PMME), PMME to phosphatidyldimethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine, PDME), and PDME to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), producing S-adenosyl-L-homocysteine in each step., [UniProtKB, HAMAP, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.17", "type": "external" }, { "id": "2.1.1.71", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.71", "type": "external" } ], "go_molecular_function": "GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity;GO:0004608 phosphatidylethanolamine N-methyltransferase activity", "go_cellular_component": "GO:0031966 mitochondrial membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006656 phosphatidylcholine biosynthetic process;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GE34-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GEM9-1", "uniprot_id": [ { "id": "A0A9J7GEM9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GEM9", "type": "external" } ], "mass": 87327.0, "length": 746, "protein_name": "Angiotensin-converting enzyme", "gene_name": "Ace3", "organism": "Hamster", "refseq_name": "angiotensin-converting enzyme-like protein Ace3", "refseq_ac": [ { "id": "XP_003503032", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503032", "type": "external" } ], "gene_names_uniprotkb": "Ace3", "gene_names_refseq": "Ace3", "protein_names_uniprotkb": "Angiotensin-converting enzyme; 3.4.-.-", "protein_names_refseq": "angiotensin-converting enzyme-like protein Ace3", "tax_id": 10029, "disease": "", "pathway": " (cge:100753209)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 2% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613926.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Soluble form that is released in blood plasma and other body fluids following proteolytic cleavage in the juxtamembrane stalk region., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.4.24.11", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.11", "type": "external" }, { "id": "3.4.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.-.-", "type": "external" } ], "go_molecular_function": "GO:0008237 metallopeptidase activity;GO:0046872 metal ion binding;GO:0004180 carboxypeptidase activity;GO:0008241 peptidyl-dipeptidase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin;GO:0003084 positive regulation of systemic arterial blood pressure;GO:1903522 regulation of blood circulation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GEM9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GGJ1-1", "uniprot_id": [ { "id": "A0A9J7GGJ1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GGJ1", "type": "external" } ], "mass": 77934.0, "length": 674, "protein_name": "Polyunsaturated fatty acid 5-lipoxygenase", "gene_name": "Alox5", "organism": "Hamster", "refseq_name": "polyunsaturated fatty acid 5-lipoxygenase isoform X1", "refseq_ac": [ { "id": "XP_027285017", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285017", "type": "external" } ], "gene_names_uniprotkb": "Alox5", "gene_names_refseq": "Alox5", "protein_names_uniprotkb": "Polyunsaturated fatty acid 5-lipoxygenase; 1.13.11.34; Arachidonate 5-lipoxygenase", "protein_names_refseq": "polyunsaturated fatty acid 5-lipoxygenase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100772492)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.13.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:1.13.11.34", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0016787 hydrolase activity;GO:0004051 arachidonate 5-lipoxygenase activity;GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen", "go_cellular_component": "GO:0005641 nuclear envelope lumen;GO:0005829 cytosol;GO:0031965 nuclear membrane;GO:0048471 perinuclear region of cytoplasm;GO:0016363 nuclear matrix", "go_biological_process": "GO:0034440 lipid oxidation;GO:0006950 response to stress;GO:0019370 leukotriene biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GGJ1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K141-1", "uniprot_id": [ { "id": "A0A9J7K141_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K141", "type": "external" } ], "mass": 117858.0, "length": 1079, "protein_name": "Hormone-sensitive lipase", "gene_name": "Lipe", "organism": "Hamster", "refseq_name": "hormone-sensitive lipase isoform X2", "refseq_ac": [ { "id": "XP_027286125", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286125", "type": "external" } ], "gene_names_uniprotkb": "Lipe", "gene_names_refseq": "Lipe", "protein_names_uniprotkb": "Hormone-sensitive lipase; 3.1.1.23; 3.1.1.79; Monoacylglycerol lipase LIPE; Retinyl ester hydrolase", "protein_names_refseq": "hormone-sensitive lipase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100755300)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "3.1.1.116", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.116", "type": "external" }, { "id": "3.3.2.9", "url": "https://www.rhea-db.org/rhea/?query=ec:3.3.2.9", "type": "external" }, { "id": "3.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.-", "type": "external" }, { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "3.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32", "type": "external" }, { "id": "3.1.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.23", "type": "external" }, { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" }, { "id": "3.1.1.34", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.34", "type": "external" }, { "id": "3.1.1.79", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.79", "type": "external" }, { "id": "3.5.1.99", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.99", "type": "external" }, { "id": "3.1.1.71", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.71", "type": "external" }, { "id": "3.1.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.6", "type": "external" } ], "go_molecular_function": "GO:0004771 sterol ester esterase activity;GO:0047372 monoacylglycerol lipase activity;GO:0004806 triacylglycerol lipase activity", "go_cellular_component": "GO:0005811 lipid droplet;GO:0005829 cytosol;GO:0005901 caveola", "go_biological_process": "GO:0008203 cholesterol metabolic process;GO:0019433 triglyceride catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K141-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GKK7-1", "uniprot_id": [ { "id": "A0A9J7GKK7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GKK7", "type": "external" } ], "mass": 180319.0, "length": 1613, "protein_name": "Low-density lipoprotein receptor-related protein", "gene_name": "Lrp6", "organism": "Hamster", "refseq_name": "low-density lipoprotein receptor-related protein 6 isoform X2", "refseq_ac": [ { "id": "XP_027285673", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285673", "type": "external" } ], "gene_names_uniprotkb": "Lrp6", "gene_names_refseq": "Lrp6", "protein_names_uniprotkb": "Low-density lipoprotein receptor-related protein", "protein_names_refseq": "low-density lipoprotein receptor-related protein 6 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772150)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in various processes including retinal angiogenesis and bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalosomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Required for posterior patterning of the epiblast during gastrulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019534 toxin transmembrane transporter activity;GO:0017147 Wnt-protein binding;GO:0042813 Wnt receptor activity", "go_cellular_component": "GO:0005769 early endosome;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0045121 membrane raft", "go_biological_process": "GO:0060856 establishment of blood-brain barrier;GO:0006897 endocytosis;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0046849 bone remodeling;GO:0042981 regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GKK7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GLP2-1", "uniprot_id": [ { "id": "A0A9J7GLP2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GLP2", "type": "external" } ], "mass": 136378.0, "length": 1212, "protein_name": "Angiopoietin-1 receptor", "gene_name": "Tek", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: angiopoietin-1 receptor isoform X2", "refseq_ac": [ { "id": "XP_035294563", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294563", "type": "external" } ], "gene_names_uniprotkb": "Tek", "gene_names_refseq": "Tek", "protein_names_uniprotkb": "Angiopoietin-1 receptor; 2.7.10.1; Endothelial tyrosine kinase; Tunica interna endothelial cell kinase; Tyrosine kinase with Ig and EGF homology domains-2; Tyrosine-protein kinase receptor TEK; Tyrosine-protein kinase receptor TIE-2; p140 TEK", "protein_names_refseq": "LOW QUALITY PROTEIN: angiopoietin-1 receptor isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100764854)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 8% of CDS bases frameshifts :: corrected 2 indels ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0005925 focal adhesion;GO:0043235 receptor complex", "go_biological_process": "GO:0001525 angiogenesis;GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0007507 heart development;GO:0043066 negative regulation of apoptotic process;GO:0043410 positive regulation of MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GLP2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GNI7-1", "uniprot_id": [ { "id": "A0A9J7GNI7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GNI7", "type": "external" } ], "mass": 38939.0, "length": 340, "protein_name": "CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1", "gene_name": "LOC113830645", "organism": "Hamster", "refseq_name": "CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase 1 isoform X2", "refseq_ac": [ { "id": "XP_027287353", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287353", "type": "external" } ], "gene_names_uniprotkb": "LOC113830645", "gene_names_refseq": "LOC113830645", "protein_names_uniprotkb": "CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1; 2.4.3.2; 2.4.3.4; Gal-NAc6S; Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase; Monosialoganglioside sialyltransferase; ST3Gal I; ST3GalA.1; ST3O; Sialyltransferase 4A", "protein_names_refseq": "CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:113830645)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048603.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.3.2", "type": "external" }, { "id": "2.4.3.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.3.4", "type": "external" } ], "go_molecular_function": "GO:0047288 beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3- sialyltransferase;GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0032580 Golgi cisterna membrane", "go_biological_process": "GO:0009101 glycoprotein biosynthetic process;GO:0097503 sialylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GNI7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GRN1-1", "uniprot_id": [ { "id": "A0A9J7GRN1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GRN1", "type": "external" } ], "mass": 93926.0, "length": 837, "protein_name": "Tyrosine-protein kinase receptor", "gene_name": "Ntrk2", "organism": "Hamster", "refseq_name": "BDNF/NT-3 growth factors receptor isoform X2", "refseq_ac": [ { "id": "XP_035297440", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297440", "type": "external" } ], "gene_names_uniprotkb": "Ntrk2", "gene_names_refseq": "Ntrk2", "protein_names_uniprotkb": "Tyrosine-protein kinase receptor; 2.7.10.1", "protein_names_refseq": "BDNF/NT-3 growth factors receptor isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754339)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0060175 brain-derived neurotrophic factor receptor activity;GO:0005524 ATP binding;GO:0048403 brain-derived neurotrophic factor binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity;GO:0005030 neurotrophin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0014069 postsynaptic density;GO:0043197 dendritic spine;GO:0043235 receptor complex;GO:0043679 axon terminus", "go_biological_process": "GO:1990416 cellular response to brain-derived neurotrophic factor stimulus;GO:0099551 trans-synaptic signaling by neuropeptide, modulating synaptic transmission;GO:0007399 nervous system development;GO:0010976 positive regulation of neuron projection development;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GRN1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GR00-1", "uniprot_id": [ { "id": "A0A9J7GR00_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GR00", "type": "external" } ], "mass": 60874.0, "length": 541, "protein_name": "Ectonucleoside triphosphate diphosphohydrolase 1", "gene_name": "Entpd1", "organism": "Hamster", "refseq_name": "ectonucleoside triphosphate diphosphohydrolase 1 isoform X2", "refseq_ac": [ { "id": "XP_035297456", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297456", "type": "external" } ], "gene_names_uniprotkb": "Entpd1", "gene_names_refseq": "Entpd1", "protein_names_uniprotkb": "Ectonucleoside triphosphate diphosphohydrolase 1; 3.6.1.5; ATP diphosphohydrolase; Ecto-ATP diphosphohydrolase 1; Ecto-apyrase; Lymphoid cell activation antigen; Nucleoside triphosphate diphosphohydrolase 1", "protein_names_refseq": "ectonucleoside triphosphate diphosphohydrolase 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762593)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 5% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the hydrolysis of nucleoside triphosphates (NTPs) and diphosphates (NDPs). The enzyme sequentially removes phosphate groups in two successive steps, converting NTPs to nucleoside monophosphates (NMPs) via NDP intermediates. This activity contributes to the regulation of extracellular levels of nucleotides. By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.1.62", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.62", "type": "external" }, { "id": "3.6.1.64", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.64", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.6", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004382 GDP phosphatase activity;GO:0045134 UDP phosphatase activity;GO:0017111 ribonucleoside triphosphate phosphatase activity;GO:0004050 apyrase activity", "go_cellular_component": "GO:0005901 caveola", "go_biological_process": "GO:0009134 nucleoside diphosphate catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GR00-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7J9K1-1", "uniprot_id": [ { "id": "A0A9J7J9K1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7J9K1", "type": "external" } ], "mass": 116816.0, "length": 1014, "protein_name": "Histone-lysine N-methyltransferase PRDM9", "gene_name": "LOC100752747", "organism": "Hamster", "refseq_name": "histone-lysine N-methyltransferase PRDM9 isoform X1", "refseq_ac": [ { "id": "XP_027256999", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256999", "type": "external" } ], "gene_names_uniprotkb": "LOC100752747", "gene_names_refseq": "LOC100752747", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase PRDM9; 2.1.1.354; 2.1.1.355; 2.1.1.359; 2.1.1.361; 2.1.1.362; PR domain zinc finger protein 9; PR domain-containing protein 9; Protein-lysine N-methyltransferase PRDM9; [histone H3]-lysine36 N-trimethyltransferase PRDM9; [histone H3]-lysine4 N-trimethyltransferase PRDM9; [histone H3]-lysine9 N-trimethyltransferase PRDM9; [histone H4]-N-methyl-L-lysine20 N-methyltransferase PRDM9; [histone H4]-lysine20 N-methyltransferase PRDM9", "protein_names_refseq": "histone-lysine N-methyltransferase PRDM9 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100752747)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" }, { "id": "2.1.1.359", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.359", "type": "external" }, { "id": "2.1.1.367", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.367", "type": "external" }, { "id": "2.1.1.354", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.354", "type": "external" }, { "id": "2.1.1.361", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.361", "type": "external" }, { "id": "2.1.1.362", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.362", "type": "external" }, { "id": "2.1.1.372", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.372", "type": "external" }, { "id": "2.1.1.355", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.355", "type": "external" }, { "id": "2.1.1.364", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.364", "type": "external" }, { "id": "3.4.24.71", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.71", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0010844 recombination hotspot binding;GO:0140941 histone H4K20me methyltransferase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005694 chromosome", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0032259 methylation;GO:0010845 positive regulation of reciprocal meiotic recombination;GO:0035825 homologous recombination;GO:0061982 meiosis I cell cycle process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7J9K1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GU73-1", "uniprot_id": [ { "id": "A0A9J7GU73_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GU73", "type": "external" } ], "mass": 54819.0, "length": 492, "protein_name": "Lysophosphatidylcholine acyltransferase 2", "gene_name": "Lpcat2", "organism": "Hamster", "refseq_name": "lysophosphatidylcholine acyltransferase 2 isoform X1", "refseq_ac": [ { "id": "XP_035298476", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298476", "type": "external" } ], "gene_names_uniprotkb": "Lpcat2", "gene_names_refseq": "Lpcat2", "protein_names_uniprotkb": "Lysophosphatidylcholine acyltransferase 2; 1-acylglycerol-3-phosphate O-acyltransferase 11; 1-acylglycerophosphocholine O-acyltransferase; 1-alkenylglycerophosphocholine O-acyltransferase; 1-alkylglycerophosphocholine O-acetyltransferase; 2.3.1.23; 2.3.1.25; 2.3.1.51; 2.3.1.67; Acetyl-CoA:lyso-platelet-activating factor acetyltransferase; Acyltransferase-like 1", "protein_names_refseq": "lysophosphatidylcholine acyltransferase 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100772716)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" }, { "id": "1.11.1.27", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.27", "type": "external" }, { "id": "2.3.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.23", "type": "external" }, { "id": "2.3.1.67", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.67", "type": "external" }, { "id": "2.3.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.25", "type": "external" }, { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" } ], "go_molecular_function": "GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0005509 calcium ion binding;GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity;GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity;GO:0047159 plasmalogen synthase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005811 lipid droplet;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006650 glycerophospholipid metabolic process;GO:0008654 phospholipid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GU73-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GU92-1", "uniprot_id": [ { "id": "A0A9J7GU92_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GU92", "type": "external" } ], "mass": 219503.0, "length": 1887, "protein_name": "Adenylate kinase 9", "gene_name": "Ak9", "organism": "Hamster", "refseq_name": "adenylate kinase 9", "refseq_ac": [ { "id": "XP_035294322", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294322", "type": "external" } ], "gene_names_uniprotkb": "Ak9", "gene_names_refseq": "Ak9", "protein_names_uniprotkb": "Adenylate kinase 9; 2.7.4.4; 2.7.4.6", "protein_names_refseq": "adenylate kinase 9", "tax_id": 10029, "disease": "", "pathway": " (cge:100752880)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613639.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Broad-specificity nucleoside phosphate kinase involved in cellular nucleotide homeostasis by catalyzing nucleoside-phosphate interconversions. Similar to other adenylate kinases, preferentially catalyzes the phosphorylation of the nucleoside monophosphate AMP with ATP as phosphate donor to produce ADP. In vitro, can also catalyze the phosphorylation of CMP, dAMP and dCMP and use GTP as an alternate phosphate donor. Moreover, exhibits a diphosphate kinase activity, producing ATP, CTP, GTP, UTP, TTP, dATP, dCTP and dGTP from the corresponding diphosphate substrates with either ATP or GTP as phosphate donors. For this activity shows the following substrate preference CDP > UDP > ADP > TDP., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "2.7.4.14", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.14", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "2.7.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.10", "type": "external" }, { "id": "2.7.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.4", "type": "external" } ], "go_molecular_function": "GO:0050145 nucleoside monophosphate kinase activity;GO:0005524 ATP binding;GO:0004550 nucleoside diphosphate kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0031514 motile cilium", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GU92-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GW57-1", "uniprot_id": [ { "id": "A0A9J7GW57_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GW57", "type": "external" } ], "mass": 58135.0, "length": 513, "protein_name": "Cytochrome P450 1A", "gene_name": "LOC100755851", "organism": "Hamster", "refseq_name": "cytochrome P450 1A2 isoform X2", "refseq_ac": [ { "id": "XP_035299618", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299618", "type": "external" } ], "gene_names_uniprotkb": "LOC100755851", "gene_names_refseq": "LOC100755851", "protein_names_uniprotkb": "Cytochrome P450 1A; 1.14.14.1", "protein_names_refseq": "cytochrome P450 1A2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100755851)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.2.1.152", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.152", "type": "external" }, { "id": "5.3.99.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.99.5", "type": "external" }, { "id": "1.14.14.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.-", "type": "external" }, { "id": "1.14.14.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.1", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004508 steroid 17-alpha-monooxygenase activity;GO:0106256 hydroperoxy icosatetraenoate dehydratase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0042446 hormone biosynthetic process;GO:0042448 progesterone metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GW57-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KD62-1", "uniprot_id": [ { "id": "A0A9J7KD62_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KD62", "type": "external" } ], "mass": 139659.0, "length": 1248, "protein_name": "Adenylate cyclase type 8", "gene_name": "LOC113837458", "organism": "Hamster", "refseq_name": "adenylate cyclase type 8 isoform X1", "refseq_ac": [ { "id": "XP_035305536", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305536", "type": "external" } ], "gene_names_uniprotkb": "LOC113837458", "gene_names_refseq": "LOC113837458", "protein_names_uniprotkb": "Adenylate cyclase type 8; 4.6.1.1", "protein_names_refseq": "adenylate cyclase type 8 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:113837458)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048603.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the formation of cAMP in response to calcium entry leadings to cAMP signaling activation that affect processes suche as synaptic plasticity and insulin secretion. Plays a role in many brain functions, such as learning, memory, drug addiction, and anxiety modulation through regulation of synaptic plasticity by modulating long-term memory and long-term potentiation (LTP) through CREB transcription factor activity modulation. Plays a central role in insulin secretion by controlling glucose homeostasis through glucagon-like peptide 1 and glucose signaling pathway and maintains insulin secretion through calcium-dependent PKA activation leading to vesicle pool replenishment. Also, allows PTGER3 to induce potentiation of PTGER4-mediated PLA2 secretion by switching from a negative to a positive regulation, during the IL1B induced-dedifferentiation of smooth muscle cells., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:4.6.1.1", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity", "go_cellular_component": "GO:0005905 clathrin-coated pit;GO:0014069 postsynaptic density;GO:0016323 basolateral plasma membrane;GO:0030425 dendrite;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0006171 cAMP biosynthetic process;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0035556 intracellular signal transduction;GO:0071377 cellular response to glucagon stimulus;GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KD62-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7J5H4-1", "uniprot_id": [ { "id": "A0A9J7J5H4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7J5H4", "type": "external" } ], "mass": 149163.0, "length": 1325, "protein_name": "Multidrug resistance-associated protein 4", "gene_name": "Abcc4", "organism": "Hamster", "refseq_name": "multidrug resistance-associated protein 4 isoform X3", "refseq_ac": [ { "id": "XP_027249742", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249742", "type": "external" } ], "gene_names_uniprotkb": "Abcc4", "gene_names_refseq": "Abcc4", "protein_names_uniprotkb": "Multidrug resistance-associated protein 4; 7.6.2.2; 7.6.2.3", "protein_names_refseq": "multidrug resistance-associated protein 4 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100766754)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds and xenobiotics from cells. Transports a range of endogenous molecules that have a key role in cellular communication and signaling, including cyclic nucleotides such as cyclic AMP (cAMP) and cyclic GMP (cGMP), bile acids, steroid conjugates, urate, and prostaglandins. Mediates the ATP-dependent efflux of glutathione conjugates such as leukotriene C4 (LTC4) and leukotriene B4 (LTB4) too. The presence of GSH is necessary for the ATP-dependent transport of LTB4, whereas GSH is not required for the transport of LTC4. Mediates the cotransport of bile acids with reduced glutathione (GSH). Transports a wide range of drugs and their metabolites, including anticancer, antiviral and antibiotic molecules. Confers resistance to anticancer agents such as methotrexate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008559 ABC-type xenobiotic transporter activity;GO:0016887 ATP hydrolysis activity;GO:0015431 ABC-type glutathione S-conjugate transporter activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0006869 lipid transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7J5H4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7J6R6-1", "uniprot_id": [ { "id": "A0A9J7J6R6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7J6R6", "type": "external" } ], "mass": 46697.0, "length": 422, "protein_name": "Acylglycerol transacylase", "gene_name": "Pnpla3", "organism": "Hamster", "refseq_name": "1-acylglycerol-3-phosphate O-acyltransferase PNPLA3", "refseq_ac": [ { "id": "XP_027251940", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251940", "type": "external" } ], "gene_names_uniprotkb": "Pnpla3", "gene_names_refseq": "Pnpla3", "protein_names_uniprotkb": "Acylglycerol transacylase; 2.3.1.51; 3.1.1.3; 3.1.1.4; Adiponutrin; Calcium-independent phospholipase A2-epsilon; Lysophosphatidic acid acyltransferase; Patatin-like phospholipase domain-containing protein 3", "protein_names_refseq": "1-acylglycerol-3-phosphate O-acyltransferase PNPLA3", "tax_id": 10029, "disease": "", "pathway": " (cge:100768979)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Specifically catalyzes coenzyme A (CoA)-dependent acylation of 1-acyl-sn-glycerol 3-phosphate (2-lysophosphatidic acid/LPA) to generate phosphatidic acid (PA), an important metabolic intermediate and precursor for both triglycerides and glycerophospholipids. Does not esterify other lysophospholipids. Acyl donors are long chain (at least C16) fatty acyl-CoAs: arachidonoyl-CoA, linoleoyl-CoA, oleoyl-CoA and at a lesser extent palmitoyl-CoA. Additionally possesses low triacylglycerol lipase and CoA-independent acylglycerol transacylase activities and thus may play a role in acyl-chain remodeling of triglycerides. In vitro may express hydrolytic activity against glycerolipids triacylglycerol, diacylglycerol and monoacylglycerol, with a strong preference for oleic acid as the acyl moiety. However, the triacylglycerol hydrolase activity is controversial and may be very low. Possesses phospholipase A2 activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" }, { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "1.11.1.27", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.27", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "3.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32", "type": "external" }, { "id": "3.1.1.116", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.116", "type": "external" }, { "id": "2.3.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.23", "type": "external" }, { "id": "2.3.1.67", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.67", "type": "external" }, { "id": "2.3.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.25", "type": "external" }, { "id": "3.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.-", "type": "external" }, { "id": "3.1.1.34", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.34", "type": "external" }, { "id": "3.1.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.23", "type": "external" }, { "id": "3.1.1.79", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.79", "type": "external" }, { "id": "3.1.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.6", "type": "external" } ], "go_molecular_function": "GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0004623 phospholipase A2 activity;GO:0036042 long-chain fatty acyl-CoA binding;GO:0004806 triacylglycerol lipase activity;GO:0035727 lysophosphatidic acid binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005811 lipid droplet;GO:0016020 membrane", "go_biological_process": "GO:0001676 long-chain fatty acid metabolic process;GO:0006654 phosphatidic acid biosynthetic process;GO:0055088 lipid homeostasis;GO:0019433 triglyceride catabolic process;GO:0019432 triglyceride biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7J6R6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7J709-1", "uniprot_id": [ { "id": "A0A9J7J709_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7J709", "type": "external" } ], "mass": 64277.0, "length": 588, "protein_name": "Omega-hydroxyceramide transacylase", "gene_name": "Pnpla1", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: patatin-like phospholipase domain-containing protein 1 isoform X2", "refseq_ac": [ { "id": "XP_027244865", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244865", "type": "external" } ], "gene_names_uniprotkb": "Pnpla1", "gene_names_refseq": "Pnpla1", "protein_names_uniprotkb": "Omega-hydroxyceramide transacylase; 2.3.1.296; Patatin-like phospholipase domain-containing protein 1", "protein_names_refseq": "LOW QUALITY PROTEIN: patatin-like phospholipase domain-containing protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763234)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Omega-hydroxyceramide transacylase involved in the synthesis of omega-O-acylceramides (esterified omega-hydroxyacyl-sphingosine; EOS), which are extremely hydrophobic lipids involved in skin barrier formation. Catalyzes the last step of the synthesis of omega-O-acylceramides by transferring linoleic acid from triglycerides to an omega-hydroxyceramide. Omega-O-acylceramides, are required for the biogenesis of lipid lamellae in the stratum corneum and the formation of the cornified lipid envelope which are essential for the epidermis barrier function. These lipids also play a role in keratinocyte differentiation. May also act on omega-hydroxylated ultra-long chain fatty acids (omega-OH ULCFA) and acylglucosylceramides (GlcEOS)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.296", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.296", "type": "external" } ], "go_molecular_function": "GO:0004806 triacylglycerol lipase activity;GO:0030280 structural constituent of skin epidermis;GO:0106341 omega-hydroxyceramide transacylase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005811 lipid droplet;GO:0016020 membrane", "go_biological_process": "GO:0055088 lipid homeostasis;GO:0019433 triglyceride catabolic process;GO:0106342 omega-hydroxyceramide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7J709-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7J8I5-1", "uniprot_id": [ { "id": "A0A9J7J8I5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7J8I5", "type": "external" } ], "mass": 61095.0, "length": 570, "protein_name": "Glutathione hydrolase 5 proenzyme", "gene_name": "Ggt5", "organism": "Hamster", "refseq_name": "glutathione hydrolase 5 proenzyme", "refseq_ac": [ { "id": "XP_027250015", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250015", "type": "external" } ], "gene_names_uniprotkb": "Ggt5", "gene_names_refseq": "Ggt5", "protein_names_uniprotkb": "Glutathione hydrolase 5 proenzyme; 2.3.2.2; 3.4.19.13; 3.4.19.14; Gamma-glutamyl leukotrienase; Gamma-glutamyltransferase 5; Gamma-glutamyltransferase-like activity 1; Gamma-glutamyltranspeptidase 5; Leukotriene-C4 hydrolase", "protein_names_refseq": "glutathione hydrolase 5 proenzyme", "tax_id": 10029, "disease": "", "pathway": " (cge:100764088)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.2", "type": "external" }, { "id": "3.4.19.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.13", "type": "external" }, { "id": "3.4.19.14", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.14", "type": "external" } ], "go_molecular_function": "GO:0002951 leukotriene-C(4) hydrolase;GO:0036374 glutathione hydrolase activity;GO:0103068 leukotriene C4 gamma-glutamyl transferase activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0006750 glutathione biosynthetic process;GO:0006751 glutathione catabolic process;GO:0006508 proteolysis;GO:0006950 response to stress;GO:0019370 leukotriene biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7J8I5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JFH6-1", "uniprot_id": [ { "id": "A0A9J7JFH6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JFH6", "type": "external" } ], "mass": 55677.0, "length": 497, "protein_name": "Hepatic triacylglycerol lipase", "gene_name": "Lipc", "organism": "Hamster", "refseq_name": "hepatic triacylglycerol lipase", "refseq_ac": [ { "id": "XP_003495111", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495111", "type": "external" } ], "gene_names_uniprotkb": "Lipc", "gene_names_refseq": "Lipc", "protein_names_uniprotkb": "Hepatic triacylglycerol lipase; 3.1.1.32; 3.1.1.3; 3.1.1.5; Lipase member C; Lysophospholipase; Phospholipase A1", "protein_names_refseq": "hepatic triacylglycerol lipase", "tax_id": 10029, "disease": "", "pathway": " (cge:100756973)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613582.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003495111.1. COMPLETENESS: full length., [RefSeq]; Catalyzes the hydrolysis of triglycerides and phospholipids present in circulating plasma lipoproteins, including chylomicrons, intermediate density lipoproteins (IDL), low density lipoproteins (LDL) of large size and high density lipoproteins (HDL), releasing free fatty acids (FFA) and smaller lipoprotein particles. Also exhibits lysophospholipase activity. Can hydrolyze both neutral lipid and phospholipid substrates but shows a greater binding affinity for neutral lipid substrates than phospholipid substrates. In native LDL, preferentially hydrolyzes the phosphatidylcholine species containing polyunsaturated fatty acids at sn-2 position., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "3.1.2.22", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.22", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "3.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32", "type": "external" }, { "id": "3.1.1.116", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.116", "type": "external" }, { "id": "3.1.1.111", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.111", "type": "external" }, { "id": "3.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.-", "type": "external" }, { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" }, { "id": "3.1.1.34", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.34", "type": "external" }, { "id": "3.1.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.23", "type": "external" }, { "id": "3.1.1.79", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.79", "type": "external" }, { "id": "3.1.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.6", "type": "external" } ], "go_molecular_function": "GO:0008201 heparin binding;GO:0034185 apolipoprotein binding;GO:0046872 metal ion binding;GO:0004622 phosphatidylcholine lysophospholipase activity;GO:0008970 phospholipase A1 activity", "go_cellular_component": "GO:0034364 high-density lipoprotein particle", "go_biological_process": "GO:0016042 lipid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JFH6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JJ82-1", "uniprot_id": [ { "id": "A0A9J7JJ82_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JJ82", "type": "external" } ], "mass": 55391.0, "length": 500, "protein_name": "N-fatty-acyl-amino acid synthase/hydrolase PM20D1", "gene_name": "Pm20d1", "organism": "Hamster", "refseq_name": "N-fatty-acyl-amino acid synthase/hydrolase PM20D1", "refseq_ac": [ { "id": "XP_027273459", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273459", "type": "external" } ], "gene_names_uniprotkb": "Pm20d1", "gene_names_refseq": "Pm20d1", "protein_names_uniprotkb": "N-fatty-acyl-amino acid synthase/hydrolase PM20D1; 3.5.1.114; 3.5.1.14; Peptidase M20 domain-containing protein 1", "protein_names_refseq": "N-fatty-acyl-amino acid synthase/hydrolase PM20D1", "tax_id": 10029, "disease": "", "pathway": " (cge:100761356)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 2% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Secreted enzyme that regulates the endogenous N-fatty acyl amino acid (NAAs) tissue and circulating levels by functioning as a bidirectional NAA synthase/hydrolase. It condenses free fatty acids and free amino acids to generate NAAs and bidirectionally catalyzes the reverse hydrolysis reaction. Some of these NAAs stimulate oxidative metabolism via mitochondrial uncoupling, increasing energy expenditure in a UPC1-independent manner. Thereby, this secreted protein may indirectly regulate whole body energy expenditure. PM20D1 circulates in tight association with both low- and high-density (LDL and HDL,respectively) lipoprotein particles., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.5.1.14", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.14", "type": "external" }, { "id": "3.5.1.114", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.114", "type": "external" }, { "id": "3.5.1.99", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.99", "type": "external" } ], "go_molecular_function": "GO:0004046 aminoacylase activity;GO:0046872 metal ion binding;GO:0008233 peptidase activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0006508 proteolysis;GO:0006629 lipid metabolic process;GO:0006520 amino acid metabolic process;GO:0043604 amide biosynthetic process;GO:0043605 amide catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JJ82-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JZE3-1", "uniprot_id": [ { "id": "A0A9J7JZE3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JZE3", "type": "external" } ], "mass": 43391.0, "length": 396, "protein_name": "Acyl-coenzyme A diphosphatase NUDT19", "gene_name": "Nudt19", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: nucleoside diphosphate-linked moiety X motif 19 isoform X2", "refseq_ac": [ { "id": "XP_027286091", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286091", "type": "external" } ], "gene_names_uniprotkb": "Nudt19", "gene_names_refseq": "Nudt19", "protein_names_uniprotkb": "Acyl-coenzyme A diphosphatase NUDT19; 3.6.1.77; Nucleoside diphosphate-linked moiety X motif 19", "protein_names_refseq": "LOW QUALITY PROTEIN: nucleoside diphosphate-linked moiety X motif 19 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100758176)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 3 indels ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027286091.1. COMPLETENESS: full length., [RefSeq]; Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate. Mediates the hydrolysis of a wide range of CoA esters, including choloyl-CoA and branched-chain fatty-acyl-CoA esters and at low substrate concentrations medium and long-chain fatty-acyl-CoA esters are the primary substrates. Highest activity seen with medium-chain acyl-CoA esters and higher rates of activity seen with the unsaturated acyl-CoA esters compared with the saturated esters. Exhibits decapping activity towards dpCoA-capped RNAs in vitro., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.9", "type": "external" }, { "id": "3.6.1.68", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.68", "type": "external" }, { "id": "3.6.1.76", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.76", "type": "external" }, { "id": "3.6.1.62", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.62", "type": "external" }, { "id": "3.6.1.64", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.64", "type": "external" }, { "id": "3.6.1.77", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.77", "type": "external" }, { "id": "3.6.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.17", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0010945 coenzyme A diphosphatase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JZE3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K7J6-1", "uniprot_id": [ { "id": "A0A9J7K7J6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K7J6", "type": "external" } ], "mass": 41967.0, "length": 371, "protein_name": "G-protein coupled estrogen receptor 1", "gene_name": "Gper1", "organism": "Hamster", "refseq_name": "G-protein coupled estrogen receptor 1", "refseq_ac": [ { "id": "XP_035300671", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300671", "type": "external" } ], "gene_names_uniprotkb": "Gper1", "gene_names_refseq": "Gper1", "protein_names_uniprotkb": "G-protein coupled estrogen receptor 1; Chemoattractant receptor-like 2; G protein-coupled estrogen receptor 1; G-protein coupled receptor 30; Membrane estrogen receptor", "protein_names_refseq": "G-protein coupled estrogen receptor 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100767871)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0030284 nuclear estrogen receptor activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005634 nucleus;GO:0005769 early endosome;GO:0005856 cytoskeleton;GO:0014069 postsynaptic density", "go_biological_process": "GO:0051223 regulation of protein transport;GO:0007399 nervous system development;GO:0030154 cell differentiation;GO:0006915 apoptotic process;GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K7J6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KBM0-1", "uniprot_id": [ { "id": "A0A9J7KBM0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KBM0", "type": "external" } ], "mass": 134636.0, "length": 1161, "protein_name": "Angiotensin-converting enzyme", "gene_name": "Ace", "organism": "Hamster", "refseq_name": "angiotensin-converting enzyme", "refseq_ac": [ { "id": "XP_035303623", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303623", "type": "external" } ], "gene_names_uniprotkb": "Ace", "gene_names_refseq": "Ace", "protein_names_uniprotkb": "Angiotensin-converting enzyme; 3.4.-.-", "protein_names_refseq": "angiotensin-converting enzyme", "tax_id": 10029, "disease": "", "pathway": " (cge:103158533)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Soluble form that is released in blood plasma and other body fluids following proteolytic cleavage in the juxtamembrane stalk region., [UniProtKB, UniProtKB]", "predicted_glycosites": 9, "predicted_n_glycosites": 9, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.4.24.11", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.11", "type": "external" }, { "id": "3.4.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.-.-", "type": "external" } ], "go_molecular_function": "GO:0008237 metallopeptidase activity;GO:0046872 metal ion binding;GO:0004180 carboxypeptidase activity;GO:0008241 peptidyl-dipeptidase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin;GO:0003084 positive regulation of systemic arterial blood pressure;GO:1903522 regulation of blood circulation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KBM0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KFS0-1", "uniprot_id": [ { "id": "A0A9J7KFS0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KFS0", "type": "external" } ], "mass": 77931.0, "length": 701, "protein_name": "Solute carrier family 15 member 1", "gene_name": "Slc15a1", "organism": "Hamster", "refseq_name": "solute carrier family 15 member 1", "refseq_ac": [ { "id": "XP_035300834", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300834", "type": "external" } ], "gene_names_uniprotkb": "Slc15a1", "gene_names_refseq": "Slc15a1", "protein_names_uniprotkb": "Solute carrier family 15 member 1; Intestinal H(+)/peptide cotransporter; Oligopeptide transporter, small intestine isoform; Peptide transporter 1; Proton-coupled dipeptide cotransporter", "protein_names_refseq": "solute carrier family 15 member 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100760826)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613586.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Electrogenic proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides. Transports neutral and monovalently charged peptides with a proton to peptide stoichiometry of 1:1 or 2:1. Primarily responsible for the absorption of dietary di- and tripeptides from the small intestinal lumen. Mediates transepithelial transport of muramyl and N-formylated bacterial dipeptides contributing to recognition of pathogenic bacteria by the mucosal immune system., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015293 symporter activity;GO:0035673 oligopeptide transmembrane transporter activity", "go_cellular_component": "GO:0016324 apical plasma membrane", "go_biological_process": "GO:0015031 protein transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KFS0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0MQH0-1", "uniprot_id": [ { "id": "DICER_CRIGR", "url": "https://www.uniprot.org/uniprot/A0MQH0", "type": "external" } ], "mass": 217171.0, "length": 1917, "protein_name": "Endoribonuclease Dicer", "gene_name": "DICER1", "organism": "Hamster", "refseq_name": "endoribonuclease Dicer", "refseq_ac": [ { "id": "NP_001231198", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231198", "type": "external" } ], "gene_names_uniprotkb": "DICER1; DICER", "gene_names_refseq": "DICER; Dicer1", "protein_names_uniprotkb": "Endoribonuclease Dicer; 3.1.26.3", "protein_names_refseq": "Dicer1, Dcr-1 homolog; dicer 1, ribonuclease type III; endoribonuclease Dicer", "tax_id": 10029, "disease": "", "pathway": " (cge:100689239)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance. The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0019904 protein domain specific binding;GO:0046872 metal ion binding;GO:0003725 double-stranded RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm;GO:0070062 extracellular exosome;GO:0016442 RISC complex", "go_biological_process": "GO:0070922 RISC complex assembly;GO:0031054 pre-miRNA processing;GO:0030422 siRNA processing;GO:0006309 apoptotic DNA fragmentation;GO:0051239 regulation of multicellular organismal process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0MQH0-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000010000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O08522-1", "uniprot_id": [ { "id": "GOSR1_CRIGR", "url": "https://www.uniprot.org/uniprot/O08522", "type": "external" } ], "mass": 28510.0, "length": 250, "protein_name": "Golgi SNAP receptor complex member 1", "gene_name": "GOSR1", "organism": "Hamster", "refseq_name": "Golgi SNAP receptor complex member 1", "refseq_ac": [ { "id": "NP_001233674", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233674", "type": "external" } ], "gene_names_uniprotkb": "GOSR1; GS28", "gene_names_refseq": "GOS-28; GS28; Gos28; Gosr1; v-SNARE", "protein_names_uniprotkb": "Golgi SNAP receptor complex member 1; 28 kDa Golgi SNARE protein; 28 kDa cis-Golgi SNARE p28; GOS-28", "protein_names_refseq": "28 kDa Golgi SNARE protein; 28 kDa cis-Golgi SNARE p28; Golgi SNAP receptor complex member 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100689312)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "8636227", "class_list": "", "function": "Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005484 SNAP receptor activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005797 Golgi medial cisterna;GO:0005801 cis-Golgi network;GO:0031201 SNARE complex;GO:0000138 Golgi trans cisterna", "go_biological_process": "GO:0015031 protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006906 vesicle fusion;GO:0006891 intra-Golgi vesicle-mediated transport;GO:0048219 inter-Golgi cisterna vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "O08522-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O08888-1", "uniprot_id": [ { "id": "PTSS2_CRIGR", "url": "https://www.uniprot.org/uniprot/O08888", "type": "external" } ], "mass": 55005.0, "length": 474, "protein_name": "Phosphatidylserine synthase 2", "gene_name": "PTDSS2", "organism": "Hamster", "refseq_name": "phosphatidylserine synthase 2", "refseq_ac": [ { "id": "NP_001233636", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233636", "type": "external" } ], "gene_names_uniprotkb": "PTDSS2; PSS2; PSSB", "gene_names_refseq": "PSS-2; PSS2; Pssb; Ptdss2", "protein_names_uniprotkb": "Phosphatidylserine synthase 2; 2.7.8.29; PSS-2; PtdSer synthase 2; Serine-exchange enzyme II", "protein_names_refseq": "PtdSer synthase 2; Serine-exchange enzyme II; phosphatidylserine synthase 2; phosphatidylserine synthase II", "tax_id": 10029, "disease": "", "pathway": " (cge:100689448)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12912985;3084470;9235902", "class_list": "", "function": "Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine (PubMed:12912985, PubMed:9235902). Catalyzes the conversion of phosphatatidylethanolamine and does not act on phosphatidylcholine (PubMed:12912985, PubMed:9235902). Shows a substrate specificity for phosphatatidylethanolamine and does not act on phosphatidylcholine (By similarity). Can utilize both phosphatidylethanolamine (PE) plasmalogen and diacyl PE as substrate and the latter is six times better utilized, indicating the importance of an ester linkage at the sn-1 position (By similarity). Although it shows no sn-1 fatty acyl preference, exhibits significant preference towards docosahexaenoic acid (22:6n-3) compared with 18:1 or 20:4 at the sn-2 position (By similarity)., [UniProtKB, UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.8.29", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.29", "type": "external" } ], "go_molecular_function": "GO:0106245 L-serine-phosphatidylethanolamine phosphatidyltransferase activity", "go_cellular_component": "GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006659 phosphatidylserine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "O08888-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O54695-1", "uniprot_id": [ { "id": "SPTC1_CRIGR", "url": "https://www.uniprot.org/uniprot/O54695", "type": "external" } ], "mass": 52520.0, "length": 473, "protein_name": "Serine palmitoyltransferase 1", "gene_name": "SPTLC1", "organism": "Hamster", "refseq_name": "serine palmitoyltransferase 1", "refseq_ac": [ { "id": "NP_001233688", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233688", "type": "external" } ], "gene_names_uniprotkb": "SPTLC1; LCB1", "gene_names_refseq": "LCB1; SPT1; Sptlc1", "protein_names_uniprotkb": "Serine palmitoyltransferase 1; 2.3.1.50; LCB 1; Long chain base biosynthesis protein 1; SPT 1; SPT1; Serine-palmitoyl-CoA transferase 1", "protein_names_refseq": "LCB 1; Long chain base biosynthesis protein 1; SPT 1; Serine-palmitoyl-CoA transferase 1; serine palmitoyltransferase 1; serine palmitoyltransferase LCB1 subunit", "tax_id": 10029, "disease": "", "pathway": " (cge:100689326)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12464627;9405408", "class_list": "", "function": "Component of the serine palmitoyltransferase multisubunit enzyme (SPT) that catalyzes the initial and rate-limiting step in sphingolipid biosynthesis by condensing L-serine and activated acyl-CoA (most commonly palmitoyl-CoA) to form long-chain bases. The SPT complex is also composed of SPTLC2 or SPTLC3 and SPTSSA or SPTSSB. Within this complex, the heterodimer with SPTLC2 or SPTLC3 forms the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, with a slight preference for C14-CoA. The SPTLC1-SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme displays an ability to use a broader range of acyl-CoAs, without apparent preference (By similarity). Required for adipocyte cell viability and metabolic homeostasis (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.50", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.50", "type": "external" } ], "go_molecular_function": "GO:0004758 serine C-palmitoyltransferase activity;GO:0030170 pyridoxal phosphate binding", "go_cellular_component": "GO:0017059 serine palmitoyltransferase complex;GO:0098554 cytoplasmic side of endoplasmic reticulum membrane", "go_biological_process": "GO:0006686 sphingomyelin biosynthetic process;GO:0006688 glycosphingolipid biosynthetic process;GO:0046513 ceramide biosynthetic process;GO:0046512 sphingosine biosynthetic process;GO:1904649 regulation of fat cell apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "O54695-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O54862-1", "uniprot_id": [ { "id": "MBTP2_CRIGR", "url": "https://www.uniprot.org/uniprot/O54862", "type": "external" } ], "mass": 56499.0, "length": 510, "protein_name": "Membrane-bound transcription factor site-2 protease", "gene_name": "MBTPS2", "organism": "Hamster", "refseq_name": "membrane-bound transcription factor site-2 protease", "refseq_ac": [ { "id": "NP_001231018", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231018", "type": "external" } ], "gene_names_uniprotkb": "MBTPS2; S2P", "gene_names_refseq": "Mbtps2; S2P", "protein_names_uniprotkb": "Membrane-bound transcription factor site-2 protease; 3.4.24.85; Endopeptidase S2P; SREBPs intramembrane protease; Sterol regulatory element-binding proteins intramembrane protease", "protein_names_refseq": "Endopeptidase S2P; SREBPs intramembrane protease; Sterol regulatory element-binding proteins intramembrane protease; membrane-bound transcription factor site-2 protease", "tax_id": 10029, "disease": "", "pathway": " (cge:100689085)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "9659902", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AF019611.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN04275174, SAMN04275175 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF019611.1., [RefSeq]; Zinc metalloprotease that mediates intramembrane proteolysis of proteins such as ATF6, ATF6B, SREBF1/SREBP1 and SREBF2/SREBP2. Catalyzes the second step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2: cleaves SREBPs within the first transmembrane segment, thereby releasing the N-terminal segment with a portion of the transmembrane segment attached. Mature N-terminal SREBP fragments shuttle to the nucleus and activate gene transcription. Also mediates the second step in the proteolytic activation of the cyclic AMP-dependent transcription factor ATF-6 (ATF6 and ATF6B). Involved in intramembrane proteolysis during bone formation. In astrocytes and osteoblasts, upon DNA damage and ER stress, mediates the second step of the regulated intramembrane proteolytic activation of the transcription factor CREB3L1, leading to the inhibition of cell-cycle progression., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140537 transcription regulator activator activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005737 cytoplasm", "go_biological_process": "GO:0008203 cholesterol metabolic process;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045542 positive regulation of cholesterol biosynthetic process;GO:0031293 membrane protein intracellular domain proteolysis;GO:0034976 response to endoplasmic reticulum stress", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "O54862-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O55044-1", "uniprot_id": [ { "id": "G6PD_CRIGR", "url": "https://www.uniprot.org/uniprot/O55044", "type": "external" } ], "mass": 59326.0, "length": 515, "protein_name": "Glucose-6-phosphate 1-dehydrogenase", "gene_name": "G6PD", "organism": "Hamster", "refseq_name": "glucose-6-phosphate 1-dehydrogenase", "refseq_ac": [ { "id": "NP_001233656", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233656", "type": "external" } ], "gene_names_uniprotkb": "G6PD", "gene_names_refseq": "G6pd", "protein_names_uniprotkb": "Glucose-6-phosphate 1-dehydrogenase; 1.-.-.-; 1.1.1.49; G6PD", "protein_names_refseq": "glucose-6-phosphate 1-dehydrogenase", "tax_id": 10029, "disease": "", "pathway": " (cge:100689469)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AF044676.1 [ECO:0000332] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF044676.1., [RefSeq]; Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis. Also catalyzes the conversion of NAADPH, which is produced by enzymes such as DUOX1, DUOX2 and NOX5 from NAADP and promotes Ca(2+) signaling during T cell activation, back to NAADP., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.31", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.31", "type": "external" }, { "id": "1.1.1.47", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.47", "type": "external" }, { "id": "1.1.1.363", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.363", "type": "external" }, { "id": "1.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.-.-.-", "type": "external" }, { "id": "1.1.1.49", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.49", "type": "external" } ], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0004345 glucose-6-phosphate dehydrogenase activity;GO:0050661 NADP binding;GO:0005536 D-glucose binding", "go_cellular_component": "GO:0005829 cytosol;GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "GO:0006739 NADP+ metabolic process;GO:0043249 erythrocyte maturation;GO:0006695 cholesterol biosynthetic process;GO:0009051 pentose-phosphate shunt, oxidative branch;GO:0006006 glucose metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "O55044-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O55076-1", "uniprot_id": [ { "id": "CDK2_CRIGR", "url": "https://www.uniprot.org/uniprot/O55076", "type": "external" } ], "mass": 33873.0, "length": 298, "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "CDK2; CDKN7", "gene_names_refseq": "", "protein_names_uniprotkb": "Cyclin-dependent kinase 2; 2.7.11.22; Cell division protein kinase 2", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "11506705", "class_list": "", "function": "Serine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis (PubMed:11506705). Phosphorylates CABLES1, CTNNB1, CDK2AP2, ERCC6, NBN, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, SUV39H1, EZH2 (By similarity). Triggers duplication of centrosomes and DNA (By similarity). Acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis, and modulates G2 progression; controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation, and coordinates the activation of cyclin B/CDK1 at the centrosome and in the nucleus (By similarity). Crucial role in orchestrating a fine balance between cellular proliferation, cell death, and DNA repair in embryonic stem cells (ESCs) (By similarity). Activated by the CDK-activating kinase (CAK) complex consisting of CDK7, cyclin-H/CCNH and MAT1, which is a master regulator of CDK activity (By similarity). Activity of CDK2 is maximal during S phase and G2; activated by interaction with cyclin E during the early stages of DNA synthesis to permit G1-S transition, and subsequently activated by cyclin A2 (cyclin A1 in germ cells) during the late stages of DNA replication to drive the transition from S phase to mitosis, the G2 phase (By similarity). EZH2 phosphorylation promotes H3K27me3 maintenance and epigenetic gene silencing (By similarity). Cyclin E/CDK2 prevents oxidative stress-mediated Ras-induced senescence by phosphorylating MYC (By similarity). Involved in G1-S phase DNA damage checkpoint that prevents cells with damaged DNA from initiating mitosis; regulates homologous recombination-dependent repair by phosphorylating BRCA2, this phosphorylation is low in S phase when recombination is active, but increases as cells progress towards mitosis (By similarity). In response to DNA damage, double-strand break repair by homologous recombination a reduction of CDK2-mediated BRCA2 phosphorylation (By similarity). Involved in regulation of telomere repair by mediating phosphorylation of NBN (By similarity). Phosphorylation of RB1 disturbs its interaction with E2F1 (By similarity). NPM1 phosphorylation by cyclin E/CDK2 promotes its dissociation from unduplicated centrosomes, thus initiating centrosome duplication (By similarity). Cyclin E/CDK2-mediated phosphorylation of NPAT at G1-S transition and until prophase stimulates the NPAT-mediated activation of histone gene transcription during S phase (By similarity). Required for vitamin D-mediated growth inhibition by being itself inactivated (By similarity). Involved in the nitric oxide- (NO) mediated signaling in a nitrosylation/activation-dependent manner (By similarity). USP37 is activated by phosphorylation and thus triggers G1-S transition (By similarity). CTNNB1 phosphorylation regulates insulin internalization (By similarity). Phosphorylates FOXP3 and negatively regulates its transcriptional activity and protein stability (By similarity). Phosphorylates ERCC6 which is essential for its chromatin remodeling activity at DNA double-strand breaks (By similarity). Acts as a regulator of the phosphatidylinositol 3-kinase/protein kinase B signal transduction by mediating phosphorylation of the C-terminus of protein kinase B (PKB/AKT1 and PKB/AKT2), promoting its activation (By similarity)., [UniProtKB, UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004693 cyclin-dependent protein serine/threonine kinase activity;GO:0030332 cyclin binding;GO:0097472 cyclin-dependent protein kinase activity", "go_cellular_component": "GO:0005768 endosome;GO:0005813 centrosome;GO:0030496 midbody;GO:0015030 Cajal body;GO:0000307 cyclin-dependent protein kinase holoenzyme complex", "go_biological_process": "GO:0006281 DNA repair;GO:0006468 protein phosphorylation;GO:0007165 signal transduction;GO:0051301 cell division;GO:0010389 regulation of G2/M transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "O55076-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P14851-1", "uniprot_id": [ { "id": "PPIA_CRIGR", "url": "https://www.uniprot.org/uniprot/P14851", "type": "external" } ], "mass": 17899.0, "length": 164, "protein_name": "Peptidyl-prolyl cis-trans isomerase A", "gene_name": "PPIA", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PPIA", "gene_names_refseq": "", "protein_names_uniprotkb": "Peptidyl-prolyl cis-trans isomerase A; 5.2.1.8; Cyclophilin A; Cyclosporin A-binding protein; PPIase A; Rotamase A", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "2408007", "class_list": "", "function": "Catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). Exerts a strong chemotactic effect on leukocytes partly through activation of one of its membrane receptors BSG/CD147, initiating a signaling cascade that culminates in MAPK/ERK activation (By similarity). Activates endothelial cells (ECs) in a proinflammatory manner by stimulating activation of NF-kappa-B and ERK, JNK and p38 MAP-kinases and by inducing expression of adhesion molecules including SELE and VCAM1 (By similarity). Induces apoptosis in ECs by promoting the FOXO1-dependent expression of CCL2 and BCL2L11 which are involved in EC chemotaxis and apoptosis (By similarity). In response to oxidative stress, initiates proapoptotic and antiapoptotic signaling in ECs via activation of NF-kappa-B and AKT1 and up-regulation of antiapoptotic protein BCL2 (By similarity). Negatively regulates MAP3K5/ASK1 kinase activity, autophosphorylation and oxidative stress-induced apoptosis mediated by MAP3K5/ASK1 (By similarity). Necessary for the assembly of TARDBP in heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and regulates TARDBP binding to RNA UG repeats and TARDBP-dependent expression of HDAC6, ATG7 and VCP which are involved in clearance of protein aggregates (By similarity). Plays an important role in platelet activation and aggregation (By similarity). Regulates calcium mobilization and integrin ITGA2B:ITGB3 bidirectional signaling via increased ROS production as well as by facilitating the interaction between integrin and the cell cytoskeleton (By similarity). Binds heparan sulfate glycosaminoglycans (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0005178 integrin binding;GO:1904399 heparan sulfate binding;GO:0016018 cyclosporin A binding;GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0030496 midbody", "go_biological_process": "GO:2001233 regulation of apoptotic signaling pathway;GO:0001934 positive regulation of protein phosphorylation;GO:0043410 positive regulation of MAPK cascade;GO:0001933 negative regulation of protein phosphorylation;GO:0006469 negative regulation of protein kinase activity", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P14851-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P18599-1", "uniprot_id": [ { "id": "5HT2A_CRIGR", "url": "https://www.uniprot.org/uniprot/P18599", "type": "external" } ], "mass": 52702.0, "length": 471, "protein_name": "5-hydroxytryptamine receptor 2A", "gene_name": "HTR2A", "organism": "Hamster", "refseq_name": "5-hydroxytryptamine receptor 2A", "refseq_ac": [ { "id": "NP_001233657", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233657", "type": "external" } ], "gene_names_uniprotkb": "HTR2A", "gene_names_refseq": "5-HT-2A; 5-HT-2; Htr2a", "protein_names_uniprotkb": "5-hydroxytryptamine receptor 2A; 5-HT-2A; 5-HT-2; Serotonin receptor 2A", "protein_names_refseq": "5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled; 5-hydroxytryptamine receptor 2A; Serotonin receptor 2A", "tax_id": 10029, "disease": "", "pathway": " (cge:100689471)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "2402449", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: X53791.1 [ECO:0000332] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X53791.1., [RefSeq]; G protein-coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR2A is coupled to G(q)/G(11) G alpha proteins and activates phospholipase C-beta, releasing diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) second messengers that modulate the activity of phosphatidylinositol 3-kinase and promote the release of Ca(2+) ions from intracellular stores, respectively. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Affects neural activity, perception, cognition and mood (By similarity). Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0030594 neurotransmitter receptor activity;GO:0051378 serotonin binding;GO:0001587 Gq/11-coupled serotonin receptor activity;GO:0071886 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding", "go_cellular_component": "GO:0030424 axon;GO:0030425 dendrite;GO:0031410 cytoplasmic vesicle;GO:0005901 caveola;GO:0098793 presynapse", "go_biological_process": "GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0006874 intracellular calcium ion homeostasis;GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268 chemical synaptic transmission;GO:0007210 serotonin receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P18599-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P18687-1", "uniprot_id": [ { "id": "CH60_CRIGR", "url": "https://www.uniprot.org/uniprot/P18687", "type": "external" } ], "mass": 60989.0, "length": 573, "protein_name": "60 kDa heat shock protein, mitochondrial", "gene_name": "HSPD1", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "HSPD1; HSP60", "gene_names_refseq": "", "protein_names_uniprotkb": "60 kDa heat shock protein, mitochondrial; 5.6.1.7; 60 kDa chaperonin; CPN60; Chaperonin 60; HSP-60; Heat shock protein 60; Hsp60; Mitochondrial matrix protein P1", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "2568357", "class_list": "", "function": "Chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp10, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and association with 2 heptameric rings of the co-chaperonin Hsp10. This leads to sequestration of the substrate protein in the inner cavity of Hsp60 where, for a certain period of time, it can fold undisturbed by other cell components. Synchronous hydrolysis of ATP in all Hsp60 subunits results in the dissociation of the chaperonin rings and the release of ADP and the folded substrate protein., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0001530 lipopolysaccharide binding;GO:0016853 isomerase activity;GO:0140662 ATP-dependent protein folding chaperone", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005759 mitochondrial matrix;GO:0005886 plasma membrane;GO:0030141 secretory granule;GO:0032991 protein-containing complex", "go_biological_process": "GO:0009409 response to cold;GO:0032729 positive regulation of type II interferon production;GO:0050870 positive regulation of T cell activation;GO:0042026 protein refolding", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P18687-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P25321-1", "uniprot_id": [ { "id": "KAPCA_CRIGR", "url": "https://www.uniprot.org/uniprot/P25321", "type": "external" } ], "mass": 40620.0, "length": 351, "protein_name": "cAMP-dependent protein kinase catalytic subunit alpha", "gene_name": "PRKACA", "organism": "Hamster", "refseq_name": "cAMP-dependent protein kinase catalytic subunit alpha isoform X1", "refseq_ac": [ { "id": "XP_016830834", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016830834", "type": "external" } ], "gene_names_uniprotkb": "PRKACA", "gene_names_refseq": "Prkaca", "protein_names_uniprotkb": "cAMP-dependent protein kinase catalytic subunit alpha; 2.7.11.11; PKA C-alpha", "protein_names_refseq": "cAMP-dependent protein kinase catalytic subunit alpha isoform X1", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "1645343", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 419 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613865.1) and transcript sequence (IACG01087049.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_016830834.1. COMPLETENESS: full length., [RefSeq]; Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, histone H1.4 (H1-4), PSMC5/RPT6, PJA2, RYR2, RORA, SLC6A6, SOX9, UHRF1 and VASP. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. RORA is activated by phosphorylation. Required for glucose-mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts (By similarity). Involved in chondrogenesis by mediating phosphorylation of SOX9 (By similarity). Involved in the regulation of platelets in response to thrombin and collagen; maintains circulating platelets in a resting state by phosphorylating proteins in numerous platelet inhibitory pathways when in complex with NF-kappa-B (NFKB1 and NFKB2) and I-kappa-B-alpha (NFKBIA), but thrombin and collagen disrupt these complexes and free active PRKACA stimulates platelets and leads to platelet aggregation by phosphorylating VASP. Prevents the antiproliferative and anti-invasive effects of alpha-difluoromethylornithine in breast cancer cells when activated. RYR2 channel activity is potentiated by phosphorylation in presence of luminal Ca(2+), leading to reduced amplitude and increased frequency of store overload-induced Ca(2+) release (SOICR) characterized by an increased rate of Ca(2+) release and propagation velocity of spontaneous Ca(2+) waves, despite reduced wave amplitude and resting cytosolic Ca(2+). PSMC5/RPT6 activation by phosphorylation stimulates proteasome. Negatively regulates tight junctions (TJs) in ovarian cancer cells via CLDN3 phosphorylation. NFKB1 phosphorylation promotes NF-kappa-B p50-p50 DNA binding (By similarity). Acts as a key inhibitor of smoothened signaling pathway by mediating phosphorylation of GLI (GLI1, GLI2 and GLI3) transcription factors in absence of hedgehog (DHH, IHH or SHH) morphogens: GLI phosphorylation promotes their processing and prevents transcriptional activation of smoothened target genes (By similarity). GLI transcription factor phosphorylation is inhibited by interaction of PRKACA with SMO which sequesters PRKACA at the cell membrane (By similarity). Also inhibits the smoothened signaling pathway in embryonic development by catalyzing phosphorylation of OFD1 in ciliogenesis (By similarity). Prevents meiosis resumption in prophase-arrested oocytes via CDC25B inactivation by phosphorylation (By similarity). May also regulate rapid eye movement (REM) sleep in the pedunculopontine tegmental (PPT) (By similarity). Phosphorylates APOBEC3G and AICDA. Phosphorylates HSF1; this phosphorylation promotes HSF1 nuclear localization and transcriptional activity upon heat shock. Acts as a negative regulator of mTORC1 by mediating phosphorylation of RPTOR. Phosphorylates AKAP19 (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0019901 protein kinase binding;GO:0019904 protein domain specific binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005811 lipid droplet", "go_biological_process": "GO:1904539 negative regulation of glycolytic process through fructose-6-phosphate;GO:0006397 mRNA processing;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0010898 positive regulation of triglyceride catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P25321-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P37879-1", "uniprot_id": [ { "id": "SYK_CRIGR", "url": "https://www.uniprot.org/uniprot/P37879", "type": "external" } ], "mass": 67990.0, "length": 597, "protein_name": "Lysine--tRNA ligase", "gene_name": "KARS1", "organism": "Hamster", "refseq_name": "lysine--tRNA ligase isoform X2", "refseq_ac": [ { "id": "XP_003510206", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510206", "type": "external" } ], "gene_names_uniprotkb": "KARS1; KARS", "gene_names_refseq": "Kars1", "protein_names_uniprotkb": "Lysine--tRNA ligase; 2.7.7.-; 6.1.1.6; LysRS; Lysyl-tRNA synthetase", "protein_names_refseq": "lysine--tRNA ligase isoform X2", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "11706011;8952483", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614840.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA (PubMed:11706011). When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of the signaling molecule diadenosine tetraphosphate (Ap4A), and thereby mediates disruption of the complex between HINT1 and MITF and the concomitant activation of MITF transcriptional activity (By similarity)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.1.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.6", "type": "external" }, { "id": "2.7.7.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0000049 tRNA binding;GO:0003877 ATP:ADP adenylyltransferase activity;GO:0004824 lysine-tRNA ligase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0043032 positive regulation of macrophage activation;GO:0015966 diadenosine tetraphosphate biosynthetic process;GO:0002276 basophil activation involved in immune response;GO:0006430 lysyl-tRNA aminoacylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P37879-1", "record_type": "protein", "filter_code": "0000000.0100100.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P41515-1", "uniprot_id": [ { "id": "TOP2A_CRIGR", "url": "https://www.uniprot.org/uniprot/P41515", "type": "external" } ], "mass": 173197.0, "length": 1526, "protein_name": "DNA topoisomerase 2-alpha", "gene_name": "TOP2A", "organism": "Hamster", "refseq_name": "DNA topoisomerase 2-alpha", "refseq_ac": [ { "id": "NP_001233667", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233667", "type": "external" } ], "gene_names_uniprotkb": "TOP2A; TOP-2; TOP2", "gene_names_refseq": "TOP-2; TOP2; Top2a", "protein_names_uniprotkb": "DNA topoisomerase 2-alpha; 5.6.2.2; DNA topoisomerase II, alpha isozyme", "protein_names_refseq": "DNA topoisomerase 2-alpha; DNA topoisomerase II, alpha isozyme; topoisomerase (DNA) II alpha 170kDa", "tax_id": 10029, "disease": "", "pathway": " (cge:100689304)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "8380592", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: L04607.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN04275174, SAMN04275175 [ECO:0000350] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from L04607.1., [RefSeq]; Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand (By similarity). May play a role in regulating the period length of BMAL1 transcriptional oscillation (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 22, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008301 DNA binding, bending;GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity;GO:0000287 magnesium ion binding;GO:0003682 chromatin binding;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0000775 chromosome, centromeric region", "go_biological_process": "GO:0000712 resolution of meiotic recombination intermediates;GO:0043065 positive regulation of apoptotic process;GO:0006974 DNA damage response;GO:0030263 apoptotic chromosome condensation;GO:0042752 regulation of circadian rhythm", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P41515-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P48538-1", "uniprot_id": [ { "id": "LEG1_CRIGR", "url": "https://www.uniprot.org/uniprot/P48538", "type": "external" } ], "mass": 14803.0, "length": 135, "protein_name": "Galectin-1", "gene_name": "LGALS1", "organism": "Hamster", "refseq_name": "galectin-1", "refseq_ac": [ { "id": "XP_003510318", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510318", "type": "external" } ], "gene_names_uniprotkb": "LGALS1", "gene_names_refseq": "Lgals1", "protein_names_uniprotkb": "Galectin-1; 14 kDa lectin; Beta-galactoside-binding lectin L-14-I; Gal-1; Galaptin; Lactose-binding lectin 1; Lectin galactoside-binding soluble 1; S-Lac lectin 1", "protein_names_refseq": "galectin-1", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "7890630", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614855.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Lectin that binds beta-galactoside and a wide array of complex carbohydrates (PubMed:7890630). Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043236 laminin binding;GO:0048018 receptor ligand activity;GO:0030395 lactose binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0043065 positive regulation of apoptotic process;GO:0006915 apoptotic process;GO:0098609 cell-cell adhesion;GO:0046598 positive regulation of viral entry into host cell;GO:0050729 positive regulation of inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P48538-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P49129-1", "uniprot_id": [ { "id": "LAMP1_CRIGR", "url": "https://www.uniprot.org/uniprot/P49129", "type": "external" } ], "mass": 43787.0, "length": 407, "protein_name": "Lysosome-associated membrane glycoprotein 1", "gene_name": "LAMP1", "organism": "Hamster", "refseq_name": "lysosome-associated membrane glycoprotein 1 precursor", "refseq_ac": [ { "id": "NP_001233759", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233759", "type": "external" } ], "gene_names_uniprotkb": "LAMP1; LGPA", "gene_names_refseq": "LAMP-1; LGP-A; Lamp1; Lgpa", "protein_names_uniprotkb": "Lysosome-associated membrane glycoprotein 1; CD107 antigen-like family member A; LAMP-1; LGP-A; Lysosomal membrane glycoprotein A; Lysosome-associated membrane protein 1", "protein_names_refseq": "CD107 antigen-like family member A; Lysosome-associated membrane glycoprotein 1; Lysosome-associated membrane protein 1; lysosomal membrane glycoprotein A; lysosome-associated membrane glycoprotein 1 precursor", "tax_id": 10029, "disease": "", "pathway": " (cge:100689406)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "8867788", "class_list": "", "function": "Lysosomal membrane glycoprotein which plays an important role in lysosome biogenesis, lysosomal pH regulation, autophagy and cholesterol homeostasis. Acts as an important regulator of lysosomal lumen pH regulation by acting as a direct inhibitor of the proton channel TMEM175, facilitating lysosomal acidification for optimal hydrolase activity. Also plays an important role in NK-cells cytotoxicity. Mechanistically, participates in cytotoxic granule movement to the cell surface and perforin trafficking to the lytic granule. In addition, protects NK-cells from degranulation-associated damage induced by their own cytotoxic granule content. Presents carbohydrate ligands to selectins., [UniProtKB, UniProtKB]", "predicted_glycosites": 21, "predicted_n_glycosites": 21, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 21, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008200 ion channel inhibitor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005764 lysosome;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0010008 endosome membrane", "go_biological_process": "GO:0072594 establishment of protein localization to organelle;GO:0050821 protein stabilization;GO:0007042 lysosomal lumen acidification", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P49129-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P50309-1", "uniprot_id": [ { "id": "G6PI_CRIGR", "url": "https://www.uniprot.org/uniprot/P50309", "type": "external" } ], "mass": 63059.0, "length": 558, "protein_name": "Glucose-6-phosphate isomerase", "gene_name": "GPI", "organism": "Hamster", "refseq_name": "glucose-6-phosphate isomerase", "refseq_ac": [ { "id": "NP_001233655", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233655", "type": "external" } ], "gene_names_uniprotkb": "GPI", "gene_names_refseq": "AMF; Gpi; NLK; PGI; PHI", "protein_names_uniprotkb": "Glucose-6-phosphate isomerase; 5.1.3.-; 5.3.1.9; AMF; Autocrine motility factor; D-hexose-6-phosphate anomerase; GPI; Glucose-6-phosphate C2-epimerase; NLK; Neuroleukin; PGI; PHI; Phosphoglucose isomerase; Phosphohexose isomerase", "protein_names_refseq": "Autocrine motility factor; D-hexose-6-phosphate anomerase; Neuroleukin; Phosphoglucose isomerase; Phosphohexose isomerase; glucose phosphate isomerase; glucose-6-phosphate C2-epimerase; glucose-6-phosphate isomerase", "tax_id": 10029, "disease": "", "pathway": " (cge:100689468)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "7604358", "class_list": "", "function": "Isomerase that catalyzes the conversion of alpha-D-glucose-6-phosphate to beta-D-fructose-6-phosphate, the second step in glycolysis, and the reverse reaction in gluconeogenesis, within the cytoplasm (By similarity). Also shows C2-epimerase activity, interconverting D-glucose-6-phosphate (G6P) and D-mannose-6-phosphate (M6P) (By similarity). Also displays anomerase activity, interconverting alpha and beta-anomeric forms of G6P, D-fructose-6-phosphate and M6P (By similarity). In addition to its metabolic role, this enzyme functions extracellularly as a cytokine: acts as autocrine motility factor (AMF), a secreted angiogenic factor that enhances endothelial cell motility. Functions as neuroleukin, a neurotrophic factor supporting the survival of spinal and sensory neurons. Released by lectin-stimulated T-cells to induce immunoglobulin secretion (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.1.9", "type": "external" }, { "id": "5.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.1.3.-", "type": "external" } ], "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding;GO:0005125 cytokine activity;GO:0004347 glucose-6-phosphate isomerase activity;GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives;GO:0097367 carbohydrate derivative binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005829 cytosol", "go_biological_process": "GO:0010595 positive regulation of endothelial cell migration;GO:0006094 gluconeogenesis;GO:0006096 glycolytic process;GO:0006002 fructose 6-phosphate metabolic process;GO:0051156 glucose 6-phosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P50309-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P57761-1", "uniprot_id": [ { "id": "PCNA_CRIGR", "url": "https://www.uniprot.org/uniprot/P57761", "type": "external" } ], "mass": 28795.0, "length": 261, "protein_name": "DNA sliding clamp PCNA", "gene_name": "PCNA", "organism": "Hamster", "refseq_name": "DNA sliding clamp PCNA", "refseq_ac": [ { "id": "NP_001233697", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233697", "type": "external" } ], "gene_names_uniprotkb": "PCNA", "gene_names_refseq": "Pcna", "protein_names_uniprotkb": "DNA sliding clamp PCNA; PCNA; Proliferating cell nuclear antigen", "protein_names_refseq": "DNA sliding clamp PCNA", "tax_id": 10029, "disease": "", "pathway": " (cge:100689335)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Confers DNA tethering and processivity to DNA polymerases and other proteins. Auxiliary protein of DNA polymerase delta and epsilon, is involved in the control of DNA replication by increasing the polymerases' processivity during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways. Acts as a loading platform to recruit DDR proteins that allow completion of DNA replication after DNA damage and promote postreplication repair: monoubiquitinated PCNA leads to recruitment of translesion (TLS) polymerases, while 'Lys-63'-linked polyubiquitination of PCNA is involved in error-free pathway and employs recombination mechanisms to synthesize across the lesion., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030337 DNA polymerase processivity factor activity;GO:0032139 dinucleotide insertion or deletion binding;GO:0003682 chromatin binding;GO:0042802 identical protein binding;GO:0003684 damaged DNA binding", "go_cellular_component": "GO:0043626 PCNA complex;GO:0070557 PCNA-p21 complex;GO:0043596 nuclear replication fork;GO:0005654 nucleoplasm;GO:0005813 centrosome", "go_biological_process": "GO:0006272 leading strand elongation;GO:0030855 epithelial cell differentiation;GO:0006298 mismatch repair;GO:0045739 positive regulation of DNA repair;GO:0045740 positive regulation of DNA replication", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "P57761-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P57797-1", "uniprot_id": [ { "id": "PPARG_CRIGR", "url": "https://www.uniprot.org/uniprot/P57797", "type": "external" } ], "mass": 54473.0, "length": 475, "protein_name": "Peroxisome proliferator-activated receptor gamma", "gene_name": "PPARG", "organism": "Hamster", "refseq_name": "peroxisome proliferator-activated receptor gamma", "refseq_ac": [ { "id": "NP_001231210", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231210", "type": "external" } ], "gene_names_uniprotkb": "PPARG; NR1C3", "gene_names_refseq": "NR1C3; PPAR-gamma; Pparg", "protein_names_uniprotkb": "Peroxisome proliferator-activated receptor gamma; Nuclear receptor subfamily 1 group C member 3; PPAR-gamma", "protein_names_refseq": "Nuclear receptor subfamily 1 group C member 3; peroxisome proliferator-activated receptor gamma", "tax_id": 10029, "disease": "", "pathway": " (cge:100689245)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "7557447", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: Z30972.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN04275174, SAMN04275175 [ECO:0000350] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from Z30972.1. On May 11, 2014 this sequence version replaced XP_007646059.1., [RefSeq]; Ligand-activated transcription factor that forms obligate heterodimers with the retinoic acid receptor and acts as a key regulator of biological processes, such as adipocyte differentiation, lipid metabolism, glucose homeostasis and beta-oxidation of fatty acids. Activated by lipid ligands: binds peroxisome proliferators, such as hypolipidemic drugs, and fatty acids, such as prostaglandin J2 metabolites. Ligand-binding results in a conformational change in the receptor, promoting dissociation of repressors and recruitment of coactivators, and subsequent activation of target gene expression. Specifically binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase (By similarity). Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated pro-inflammatory responses (By similarity). Plays a role in the regulation of cardiovascular circadian rhythms by regulating the transcription of BMAL1 in the blood vessels (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Nuclear receptor that acts as the key factor controlling the development of adipocytes. Specifically activated by 15-deoxy-delta12,14-prostaglandin J2 ligand during early adipogenesis, driving differentiation of all types of adipocytes (white, beige and brown). Acts together with retinoic acid receptor RXRA, forming the ARF6 complex, which acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Following recruitment of TLE3, promotes differentiation of white adipocytes. Following recruitment of PRDM16, promotes differentiation of myoblastic precursors into brown adipose cells (BAT), which are specialized in dissipating energy in the form of heat in response to cold or excess feeding. Also mediates diffentiation of white adipocytes into beige adipocytes by mediating recruitment of PRDM16., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000976 transcription cis-regulatory region binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006631 fatty acid metabolic process;GO:0010629 negative regulation of gene expression;GO:0032869 cellular response to insulin stimulus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P57797-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P62629-1", "uniprot_id": [ { "id": "EF1A1_CRIGR", "url": "https://www.uniprot.org/uniprot/P62629", "type": "external" } ], "mass": 50114.0, "length": 462, "protein_name": "Elongation factor 1-alpha 1", "gene_name": "EEF1A1", "organism": "Hamster", "refseq_name": "elongation factor 1-alpha 1", "refseq_ac": [ { "id": "NP_001231331", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231331", "type": "external" } ], "gene_names_uniprotkb": "EEF1A1; EEF1A", "gene_names_refseq": "EEF1A; EF-Tu; Eef1a1; eEF1A-1", "protein_names_uniprotkb": "Elongation factor 1-alpha 1; 3.6.5.-; EF-1-alpha-1; EF-Tu; Elongation factor Tu; Eukaryotic elongation factor 1 A-1; eEF1A-1", "protein_names_refseq": "EF-1-alpha-1; Elongation factor Tu; Eukaryotic elongation factor 1 A-1; elongation factor 1-alpha 1; elongation factor EF-1 alpha", "tax_id": 10029, "disease": "", "pathway": " (cge:100689276)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "2606910", "class_list": "", "function": "Translation elongation factor that catalyzes the GTP-dependent binding of aminoacyl-tRNA (aa-tRNA) to the A-site of ribosomes during the elongation phase of protein synthesis. Base pairing between the mRNA codon and the aa-tRNA anticodon promotes GTP hydrolysis, releasing the aa-tRNA from EEF1A1 and allowing its accommodation into the ribosome. The growing protein chain is subsequently transferred from the P-site peptidyl tRNA to the A-site aa-tRNA, extending it by one amino acid through ribosome-catalyzed peptide bond formation. Also plays a role in the positive regulation of IFNG transcription in T-helper 1 cells as part of an IFNG promoter-binding complex with TXK and PARP1 (By similarity). Also plays a role in cytoskeleton organization by promoting actin bundling (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P20001", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" } ], "go_molecular_function": "GO:0019209 kinase activator activity;GO:0003924 GTPase activity;GO:0005516 calmodulin binding;GO:0005525 GTP binding;GO:0003746 translation elongation factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0071364 cellular response to epidermal growth factor stimulus;GO:0006414 translational elongation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P62629-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P68180-1", "uniprot_id": [ { "id": "KAPCB_CRIGR", "url": "https://www.uniprot.org/uniprot/P68180", "type": "external" } ], "mass": 40708.0, "length": 351, "protein_name": "cAMP-dependent protein kinase catalytic subunit beta", "gene_name": "PRKACB", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PRKACB; PKACB", "gene_names_refseq": "", "protein_names_uniprotkb": "cAMP-dependent protein kinase catalytic subunit beta; 2.7.11.11; PKA C-beta", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "1645343", "class_list": "", "function": "Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates GPKOW which regulates its ability to bind RNA. Acts as a negative regulator of mTORC1 by mediating phosphorylation of RPTOR., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P05206", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0004691 cAMP-dependent protein kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005952 cAMP-dependent protein kinase complex", "go_biological_process": "GO:0006468 protein phosphorylation;GO:1904262 negative regulation of TORC1 signaling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P68180-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P68365-1", "uniprot_id": [ { "id": "TBA1C_CRIGR", "url": "https://www.uniprot.org/uniprot/P68365", "type": "external" } ], "mass": 49909.0, "length": 449, "protein_name": "Tubulin alpha-1C chain", "gene_name": "TUBA1C", "organism": "Hamster", "refseq_name": "tubulin alpha-1C chain", "refseq_ac": [ { "id": "NP_001230906", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230906", "type": "external" } ], "gene_names_uniprotkb": "TUBA1C; TUBA3", "gene_names_refseq": "Tuba1c; Tuba3", "protein_names_uniprotkb": "Tubulin alpha-1C chain; 3.6.5.-; Alpha-tubulin 3; Alpha-tubulin III; Tubulin alpha-3 chain", "protein_names_refseq": "Alpha-tubulin 3; Tubulin alpha-3 chain; alpha-tubulin III; tubulin alpha-1C chain", "tax_id": 10029, "disease": "", "pathway": " (cge:100682526)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "3773896", "class_list": "", "function": "Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P05216;Q9CSE9", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" } ], "go_molecular_function": "GO:0005200 structural constituent of cytoskeleton;GO:0005525 GTP binding;GO:0016787 hydrolase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005929 cilium;GO:0005881 cytoplasmic microtubule", "go_biological_process": "GO:0007017 microtubule-based process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P68365-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P70099-1", "uniprot_id": [ { "id": "RAD51_CRIGR", "url": "https://www.uniprot.org/uniprot/P70099", "type": "external" } ], "mass": 36941.0, "length": 339, "protein_name": "DNA repair protein RAD51 homolog 1", "gene_name": "RAD51", "organism": "Hamster", "refseq_name": "DNA repair protein RAD51 homolog 1", "refseq_ac": [ { "id": "NP_001233686", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233686", "type": "external" } ], "gene_names_uniprotkb": "RAD51; RAD51A", "gene_names_refseq": "RAD51A; Rad51", "protein_names_uniprotkb": "DNA repair protein RAD51 homolog 1; 3.6.4.-", "protein_names_refseq": "DNA repair protein RAD51 homolog 1; DNA repair protein RAD51-like 1; RAD51 homolog", "tax_id": 10029, "disease": "", "pathway": " (cge:100689324)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "9611228", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: Y08202.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN04275174, SAMN04275175 [ECO:0000350] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from Y08202.1., [RefSeq]; Homologous DNA recombinase that catalyzes strand exchange, a key step in DNA repair through homologous recombination (HR). Binds to single-stranded DNA (ssDNA) in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. RAD51 targeting to ssDNA promotes removal of replication protein-A (RPA) from ssDNA and stabilization of RAD51-ssDNA filaments by blocking ATP hydrolysis. Nucleosomal DNA is peeled from the histone surface by the RAD51 filament. Recruited to resolve stalled replication forks during replication stress. Also required for homologous recombination during meiosis by acting as an non-catalytic accessory factor for DMC1 recombinase, enabling proper chromosome pairing and crossing over. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3. Also involved in interstrand cross-link repair., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0046872 metal ion binding;GO:0003690 double-stranded DNA binding;GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005759 mitochondrial matrix;GO:0005813 centrosome", "go_biological_process": "GO:0006312 mitotic recombination;GO:0006974 DNA damage response;GO:0000724 double-strand break repair via homologous recombination;GO:0071479 cellular response to ionizing radiation;GO:0036297 interstrand cross-link repair", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P70099-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P97259-1", "uniprot_id": [ { "id": "MGT5A_CRIGR", "url": "https://www.uniprot.org/uniprot/P97259", "type": "external" } ], "mass": 84561.0, "length": 740, "protein_name": "Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A", "gene_name": "MGAT5", "organism": "Hamster", "refseq_name": "alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A", "refseq_ac": [ { "id": "XP_007613026", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007613026", "type": "external" } ], "gene_names_uniprotkb": "MGAT5", "gene_names_refseq": "Mgat5", "protein_names_uniprotkb": "Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A; 2.4.1.155; Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase; GNT-V; GlcNAc-T V; Mannoside acetylglucosaminyltransferase 5; N-acetylglucosaminyl-transferase V; Secreted GNT-V; Secreted beta-1,6-N-acetylglucosaminyltransferase V", "protein_names_refseq": "alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "8910328", "class_list": "glycogene;glycosyltransferase", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613656.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the addition of N-acetylglucosamine (GlcNAc) in beta 1-6 linkage to the alpha-linked mannose of biantennary N-linked oligosaccharides (PubMed:8910328). Catalyzes an important step in the biosynthesis of branched, complex-type N-glycans, such as those found on EGFR, TGFR (TGF-beta receptor) and CDH2. Via its role in the biosynthesis of complex N-glycans, plays an important role in the activation of cellular signaling pathways, reorganization of the actin cytoskeleton, cell-cell adhesion and cell migration. MGAT5-dependent EGFR N-glycosylation enhances the interaction between EGFR and LGALS3 and thereby prevents rapid EGFR endocytosis and prolongs EGFR signaling. Required for efficient interaction between TGFB1 and its receptor. Enhances activation of intracellular signaling pathways by several types of growth factors, including FGF2, PDGF, IGF, TGFB1 and EGF. MGAT5-dependent CDH2 N-glycosylation inhibits CDH2-mediated homotypic cell-cell adhesion and contributes to the regulation of downstream signaling pathways. Promotes cell migration. Contributes to the regulation of the inflammatory response. MGAT5-dependent TCR N-glycosylation enhances the interaction between TCR and LGALS3, limits agonist-induced TCR clustering, and thereby dampens TCR-mediated responses to antigens. Required for normal leukocyte evasation and accumulation at sites of inflammation (By similarity). Inhibits attachment of monocytes to the vascular endothelium and subsequent monocyte diapedesis (By similarity)., [UniProtKB, UniProtKB, UniProtKB, PubMed]; Promotes proliferation of umbilical vein endothelial cells and angiogenesis, at least in part by promoting the release of the growth factor FGF2 from the extracellular matrix., [UniProtKB, UniProtKB]", "predicted_glycosites": 6, "predicted_n_glycosites": 6, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "P70100;P70101", "ec_number_list": [ { "id": "2.4.1.155", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.155", "type": "external" } ], "go_molecular_function": "GO:0030145 manganese ion binding;GO:0004864 protein phosphatase inhibitor activity;GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005576 extracellular region", "go_biological_process": "GO:0030335 positive regulation of cell migration;GO:0006487 protein N-linked glycosylation;GO:1904894 positive regulation of receptor signaling pathway via STAT", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P97259-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000010000.001.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q06438-1", "uniprot_id": [ { "id": "PEX2_CRIGR", "url": "https://www.uniprot.org/uniprot/Q06438", "type": "external" } ], "mass": 34795.0, "length": 304, "protein_name": "Peroxisome biogenesis factor 2", "gene_name": "PEX2", "organism": "Hamster", "refseq_name": "peroxisome biogenesis factor 2", "refseq_ac": [ { "id": "NP_001230964", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230964", "type": "external" } ], "gene_names_uniprotkb": "PEX2; PAF1; PMP35; PXMP3", "gene_names_refseq": "PAF-1; PMP35; Paf1; Peroxin-2; Pex2; Pxmp3", "protein_names_uniprotkb": "Peroxisome biogenesis factor 2; 2.3.2.27; 2.3.2.36; PAF-1; Peroxin-2; Peroxisomal membrane protein 3; Peroxisome assembly factor 1", "protein_names_refseq": "peroxisomal membrane protein 3; peroxisome assembly factor 1; peroxisome biogeneis factor 2; peroxisome biogenesis factor 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100689047)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "33240873;7685346;8035823;9765053", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: Z17220.1 [ECO:0000332] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from Z17220.1., [RefSeq]; E3 ubiquitin-protein ligase component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling (By similarity). The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 through the peroxisomal membrane. PEX2 also regulates peroxisome organization by acting as a E3 ubiquitin-protein ligase. PEX2 ubiquitinates PEX5 during its passage through the retrotranslocation channel: catalyzes monoubiquitination of PEX5 at 'Cys-11', a modification that acts as a signal for PEX5 extraction into the cytosol (By similarity). Required for pexophagy in response to starvation by mediating ubiquitination of peroxisomal proteins, such as PEX5 and ABCD3/PMP70. Also involved in the response to reactive oxygen species (ROS) by mediating 'Lys-48'-linked polyubiquitination and subsequent degradation of PNPLA2/ATGL, thereby regulating lipolysis (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005778 peroxisomal membrane;GO:0016593 Cdc73/Paf1 complex", "go_biological_process": "GO:0000038 very long-chain fatty acid metabolic process;GO:0006635 fatty acid beta-oxidation;GO:0007031 peroxisome organization;GO:0050680 negative regulation of epithelial cell proliferation;GO:0048147 negative regulation of fibroblast proliferation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q06438-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q60415-1", "uniprot_id": [ { "id": "PEX19_CRIGR", "url": "https://www.uniprot.org/uniprot/Q60415", "type": "external" } ], "mass": 32627.0, "length": 299, "protein_name": "Peroxisomal biogenesis factor 19", "gene_name": "PEX19", "organism": "Hamster", "refseq_name": "peroxisomal biogenesis factor 19", "refseq_ac": [ { "id": "NP_001233665", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233665", "type": "external" } ], "gene_names_uniprotkb": "PEX19; PXF", "gene_names_refseq": "Peroxin-19; Pex19; Pxf", "protein_names_uniprotkb": "Peroxisomal biogenesis factor 19; Peroxin-19; Peroxisomal farnesylated protein", "protein_names_refseq": "Peroxisomal farnesylated protein; peroxisomal biogenesis factor 19", "tax_id": 10029, "disease": "", "pathway": " (cge:100689302)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "8188701", "class_list": "", "function": "Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0036105 peroxisome membrane class-1 targeting sequence binding;GO:0051117 ATPase binding;GO:0140597 protein carrier chaperone", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005778 peroxisomal membrane;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0016559 peroxisome fission;GO:0007031 peroxisome organization;GO:0050821 protein stabilization;GO:0006457 protein folding;GO:0006625 protein targeting to peroxisome", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q60415-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q60416-1", "uniprot_id": [ { "id": "SRBP1_CRIGR", "url": "https://www.uniprot.org/uniprot/Q60416", "type": "external" } ], "mass": 120466.0, "length": 1133, "protein_name": "Sterol regulatory element-binding protein 1", "gene_name": "SREBF1", "organism": "Hamster", "refseq_name": "sterol regulatory element-binding protein 1", "refseq_ac": [ { "id": "NP_001230932", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230932", "type": "external" } ], "gene_names_uniprotkb": "SREBF1; SREBP1", "gene_names_refseq": "SREBP-1; SREBP1; Srebf1", "protein_names_uniprotkb": "Sterol regulatory element-binding protein 1; SREBP-1; Sterol regulatory element-binding transcription factor 1; Transcription factor SREBF1", "protein_names_refseq": "Sterol regulatory element-binding transcription factor 1; sterol regulatory element binding protein-1; sterol regulatory element-binding protein 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100689018)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "8006035", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: U09103.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN09948091 [ECO:0000350] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U09103.1., [RefSeq]; Key transcription factor that regulates expression of genes involved in cholesterol biosynthesis and lipid homeostasis. Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3'). Regulates the promoters of genes involved in cholesterol biosynthesis and the LDL receptor (LDLR) pathway of sterol regulation., [UniProtKB, UniProtKB]; Precursor of the transcription factor form (Processed sterol regulatory element-binding protein 1), which is embedded in the endoplasmic reticulum membrane (By similarity). Low sterol concentrations promote processing of this form, releasing the transcription factor form that translocates into the nucleus and activates transcription of genes involved in cholesterol biosynthesis and lipid homeostasis (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0019901 protein kinase binding;GO:0046983 protein dimerization activity;GO:0004879 nuclear receptor activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005789 endoplasmic reticulum membrane;GO:0012507 ER to Golgi transport vesicle membrane", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0008203 cholesterol metabolic process;GO:0008610 lipid biosynthetic process;GO:0045542 positive regulation of cholesterol biosynthetic process;GO:0007623 circadian rhythm", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q60416-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q60417-1", "uniprot_id": [ { "id": "SCRB1_CRIGR", "url": "https://www.uniprot.org/uniprot/Q60417", "type": "external" } ], "mass": 56735.0, "length": 509, "protein_name": "Scavenger receptor class B member 1", "gene_name": "SCARB1", "organism": "Hamster", "refseq_name": "scavenger receptor class B member 1", "refseq_ac": [ { "id": "NP_001231777", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231777", "type": "external" } ], "gene_names_uniprotkb": "SCARB1", "gene_names_refseq": "SR-BI; SRB1; Scarb1; haSR-bI", "protein_names_uniprotkb": "Scavenger receptor class B member 1; HaSR-BI; SR-BI; SRB1", "protein_names_refseq": "CD36-related class B scavenger receptor haSR-BI; scavenger receptor class B member 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100736552)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "7520436", "class_list": "", "function": "Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux. Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 9, "predicted_n_glycosites": 9, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0070506 high-density lipoprotein particle receptor activity;GO:0005044 scavenger receptor activity;GO:0001540 amyloid-beta binding;GO:0034186 apolipoprotein A-I binding;GO:0008035 high-density lipoprotein particle binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0009986 cell surface;GO:0005901 caveola", "go_biological_process": "GO:0044406 adhesion of symbiont to host;GO:1902070 positive regulation of sphingolipid mediated signaling pathway;GO:0015914 phospholipid transport;GO:0033344 cholesterol efflux;GO:0034375 high-density lipoprotein particle remodeling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q60417-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q60506-1", "uniprot_id": [ { "id": "PRIO_CRIGR", "url": "https://www.uniprot.org/uniprot/Q60506", "type": "external" } ], "mass": 27823.0, "length": 254, "protein_name": "Major prion protein", "gene_name": "PRNP", "organism": "Hamster", "refseq_name": "major prion protein", "refseq_ac": [ { "id": "XP_003499061", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499061", "type": "external" } ], "gene_names_uniprotkb": "PRNP; PRP", "gene_names_refseq": "Prnp", "protein_names_uniprotkb": "Major prion protein; PrP27-30; PrP33-35C; PrP", "protein_names_refseq": "major prion protein", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "2406562", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613715.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or Zn(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0002020 protease binding;GO:0008017 microtubule binding;GO:0042802 identical protein binding;GO:0001540 amyloid-beta binding;GO:0031802 type 5 metabotropic glutamate receptor binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0030425 dendrite", "go_biological_process": "GO:0032700 negative regulation of interleukin-17 production;GO:0032703 negative regulation of interleukin-2 production;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0007611 learning or memory;GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q60506-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q64395-1", "uniprot_id": [ { "id": "PDE1B_CRIGR", "url": "https://www.uniprot.org/uniprot/Q64395", "type": "external" } ], "mass": 61254.0, "length": 535, "protein_name": "Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B", "gene_name": "PDE1B1", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PDE1B1", "gene_names_refseq": "", "protein_names_uniprotkb": "Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B; 3.1.4.17; Cam-PDE 1B", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "21804562;9003415", "class_list": "", "function": "Cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a preference for cGMP as a substrate., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.4.35", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.35", "type": "external" }, { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" }, { "id": "3.1.4.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.53", "type": "external" }, { "id": "3.1.4.17", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.17", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004112 cyclic-nucleotide phosphodiesterase activity;GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity;GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0007165 signal transduction;GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus;GO:0030224 monocyte differentiation;GO:0036006 cellular response to macrophage colony-stimulating factor stimulus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q64395-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F773-1", "uniprot_id": [ { "id": "A0A9J7F773_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F773", "type": "external" } ], "mass": 64660.0, "length": 598, "protein_name": "Pyruvate kinase", "gene_name": "Pklr", "organism": "Hamster", "refseq_name": "pyruvate kinase PKLR isoform X1", "refseq_ac": [ { "id": "XP_007640427", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640427", "type": "external" } ], "gene_names_uniprotkb": "Pklr", "gene_names_refseq": "Pklr", "protein_names_uniprotkb": "Pyruvate kinase; 2.7.1.40", "protein_names_refseq": "pyruvate kinase PKLR isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100755461)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613854.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Pyruvate kinase isoform expressed in adult tissues, which replaces isoform M2 after birth. In contrast to isoform M2, has high pyruvate kinase activity by itself and does not require allosteric activation by D-fructose 1,6-bisphosphate (FBP) for activity., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004674 protein serine/threonine kinase activity;GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0030955 potassium ion binding", "go_cellular_component": "", "go_biological_process": "GO:0006417 regulation of translation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F773-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F910-1", "uniprot_id": [ { "id": "A0A9J7F910_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F910", "type": "external" } ], "mass": 145794.0, "length": 1359, "protein_name": "Adhesion G protein-coupled receptor A2", "gene_name": "Adgra2", "organism": "Hamster", "refseq_name": "adhesion G protein-coupled receptor A2 isoform X2", "refseq_ac": [ { "id": "XP_027251185", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251185", "type": "external" } ], "gene_names_uniprotkb": "Adgra2", "gene_names_refseq": "Adgra2", "protein_names_uniprotkb": "Adhesion G protein-coupled receptor A2; G-protein coupled receptor 124; Tumor endothelial marker 5", "protein_names_refseq": "adhesion G protein-coupled receptor A2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100751137)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027251185.1. COMPLETENESS: full length., [RefSeq]; Endothelial receptor which functions together with RECK to enable brain endothelial cells to selectively respond to Wnt7 signals (WNT7A or WNT7B). Plays a key role in Wnt7-specific responses, such as endothelial cell sprouting and migration in the forebrain and neural tube, and establishment of the blood-brain barrier. Acts as a Wnt7-specific coactivator of canonical Wnt signaling: required to deliver RECK-bound Wnt7 to frizzled by assembling a higher-order RECK-ADGRA2-Fzd-LRP5-LRP6 complex. ADGRA2-tethering function does not rely on its G-protein coupled receptor (GPCR) structure but instead on its combined capacity to interact with RECK extracellularly and recruit the Dishevelled scaffolding protein intracellularly. Binds to the glycosaminoglycans heparin, heparin sulfate, chondroitin sulfate and dermatan sulfate., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030175 filopodium;GO:1990909 Wnt signalosome", "go_biological_process": "GO:0007417 central nervous system development;GO:0016055 Wnt signaling pathway;GO:0002040 sprouting angiogenesis;GO:0090263 positive regulation of canonical Wnt signaling pathway;GO:0007166 cell surface receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F910-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F7J1-1", "uniprot_id": [ { "id": "A0A9J7F7J1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F7J1", "type": "external" } ], "mass": 114647.0, "length": 1013, "protein_name": "Metalloendopeptidase", "gene_name": "Tll1", "organism": "Hamster", "refseq_name": "tolloid-like protein 1", "refseq_ac": [ { "id": "XP_027249907", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249907", "type": "external" } ], "gene_names_uniprotkb": "Tll1", "gene_names_refseq": "Tll1", "protein_names_uniprotkb": "Metalloendopeptidase; 3.4.24.-", "protein_names_refseq": "tolloid-like protein 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100755072)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027249907.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008270 zinc ion binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0006508 proteolysis;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F7J1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F7T3-1", "uniprot_id": [ { "id": "A0A9J7F7T3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F7T3", "type": "external" } ], "mass": 49530.0, "length": 439, "protein_name": "5-hydroxytryptamine receptor 2B", "gene_name": "Htr2b", "organism": "Hamster", "refseq_name": "5-hydroxytryptamine receptor 2B", "refseq_ac": [ { "id": "XP_007653438", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653438", "type": "external" } ], "gene_names_uniprotkb": "Htr2b", "gene_names_refseq": "Htr2b", "protein_names_uniprotkb": "5-hydroxytryptamine receptor 2B; 5-HT-2F; Serotonin receptor 2B", "protein_names_refseq": "5-hydroxytryptamine receptor 2B", "tax_id": 10029, "disease": "", "pathway": " (cge:103161688)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003617646.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007653438.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004993 G protein-coupled serotonin receptor activity;GO:0030594 neurotransmitter receptor activity;GO:0051378 serotonin binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0045202 synapse", "go_biological_process": "GO:0006939 smooth muscle contraction;GO:0007507 heart development;GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268 chemical synaptic transmission;GO:0007210 serotonin receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F7T3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F8V5-1", "uniprot_id": [ { "id": "A0A9J7F8V5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F8V5", "type": "external" } ], "mass": 57460.0, "length": 510, "protein_name": "Serine/threonine-protein kinase Nek3", "gene_name": "Nek3", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase Nek3 isoform X1", "refseq_ac": [ { "id": "XP_016831542", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831542", "type": "external" } ], "gene_names_uniprotkb": "Nek3", "gene_names_refseq": "Nek3", "protein_names_uniprotkb": "Serine/threonine-protein kinase Nek3; 2.7.11.1; Never in mitosis A-related kinase 3", "protein_names_refseq": "serine/threonine-protein kinase Nek3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100771488)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613958.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0030424 axon", "go_biological_process": "GO:0051301 cell division", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F8V5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F821-1", "uniprot_id": [ { "id": "A0A9J7F821_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F821", "type": "external" } ], "mass": 132676.0, "length": 1228, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Hipk1", "organism": "Hamster", "refseq_name": "homeodomain-interacting protein kinase 1 isoform X1", "refseq_ac": [ { "id": "XP_003505861", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505861", "type": "external" } ], "gene_names_uniprotkb": "Hipk1", "gene_names_refseq": "Hipk1", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "homeodomain-interacting protein kinase 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100759237)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614192.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003505861.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016605 PML body;GO:0005829 cytosol;GO:0016607 nuclear speck", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0007224 smoothened signaling pathway;GO:0060059 embryonic retina morphogenesis in camera-type eye;GO:0030182 neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F821-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F828-1", "uniprot_id": [ { "id": "A0A9J7F828_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F828", "type": "external" } ], "mass": 91281.0, "length": 827, "protein_name": "Disintegrin and metalloproteinase domain-containing protein 9 isoform X4", "gene_name": "Adam9", "organism": "Hamster", "refseq_name": "disintegrin and metalloproteinase domain-containing protein 9 isoform X4", "refseq_ac": [ { "id": "XP_027251116", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251116", "type": "external" } ], "gene_names_uniprotkb": "Adam9", "gene_names_refseq": "Adam9", "protein_names_uniprotkb": "Disintegrin and metalloproteinase domain-containing protein 9 isoform X4", "protein_names_refseq": "disintegrin and metalloproteinase domain-containing protein 9 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100754662)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0005178 integrin binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane", "go_biological_process": "GO:0006509 membrane protein ectodomain proteolysis;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0033631 cell-cell adhesion mediated by integrin", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F828-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F844-1", "uniprot_id": [ { "id": "A0A9J7F844_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F844", "type": "external" } ], "mass": 29317.0, "length": 261, "protein_name": "Phospholipid phosphatase 5", "gene_name": "Plpp5", "organism": "Hamster", "refseq_name": "phospholipid phosphatase 5 isoform X1", "refseq_ac": [ { "id": "XP_027251155", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251155", "type": "external" } ], "gene_names_uniprotkb": "Plpp5", "gene_names_refseq": "Plpp5", "protein_names_uniprotkb": "Phospholipid phosphatase 5; 3.1.3.4; 3.6.1.75", "protein_names_refseq": "phospholipid phosphatase 5 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100772808)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Magnesium-independent phospholipid phosphatase with broad substrate specificity. Preferentially catalyzes the conversion of diacylglycerol pyrophosphate into phosphatidate but can also act on phosphatidate and lysophosphatidate. Phospholipid phosphatases are involved in both the synthesis of lipids and the generation or degradation of lipid-signaling molecules., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.3.2.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.3.2.10", "type": "external" }, { "id": "3.1.3.76", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.76", "type": "external" }, { "id": "3.1.3.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.4", "type": "external" }, { "id": "3.1.3.106", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.106", "type": "external" }, { "id": "3.6.1.75", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.75", "type": "external" } ], "go_molecular_function": "GO:0008195 phosphatidate phosphatase activity;GO:0000810 diacylglycerol diphosphate phosphatase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0006644 phospholipid metabolic process;GO:0046839 phospholipid dephosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F844-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F854-1", "uniprot_id": [ { "id": "A0A9J7F854_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F854", "type": "external" } ], "mass": 44098.0, "length": 377, "protein_name": "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "gene_name": "Fnta", "organism": "Hamster", "refseq_name": "protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha isoform X2", "refseq_ac": [ { "id": "XP_027251173", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251173", "type": "external" } ], "gene_names_uniprotkb": "Fnta", "gene_names_refseq": "Fnta", "protein_names_uniprotkb": "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; 2.5.1.58; 2.5.1.59; CAAX farnesyltransferase subunit alpha; FTase-alpha; Ras proteins prenyltransferase subunit alpha; Type I protein geranyl-geranyltransferase subunit alpha", "protein_names_refseq": "protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100752295)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.5.1.59", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.59", "type": "external" }, { "id": "2.5.1.60", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.60", "type": "external" }, { "id": "2.5.1.58", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.58", "type": "external" } ], "go_molecular_function": "GO:0004660 protein farnesyltransferase activity;GO:0004662 CAAX-protein geranylgeranyltransferase activity", "go_cellular_component": "GO:0005953 CAAX-protein geranylgeranyltransferase complex;GO:0005965 protein farnesyltransferase complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F854-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F861-1", "uniprot_id": [ { "id": "A0A9J7F861_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F861", "type": "external" } ], "mass": 43887.0, "length": 390, "protein_name": "G/T mismatch-specific thymine DNA glycosylase", "gene_name": "LOC100752484", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: G/T mismatch-specific thymine DNA glycosylase isoform X2", "refseq_ac": [ { "id": "XP_027249701", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249701", "type": "external" } ], "gene_names_uniprotkb": "LOC100752484", "gene_names_refseq": "LOC100752484", "protein_names_uniprotkb": "G/T mismatch-specific thymine DNA glycosylase; 3.2.2.29; Thymine-DNA glycosylase", "protein_names_refseq": "LOW QUALITY PROTEIN: G/T mismatch-specific thymine DNA glycosylase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100752484)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 2 indels internal stop codons :: corrected 2 genomic stop codons ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027249701.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0004844 uracil DNA N-glycosylase activity;GO:0032183 SUMO binding;GO:0141016 G/T mismatch-specific thymine-DNA glycosylase activity", "go_cellular_component": "GO:0005654 nucleoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0040029 epigenetic regulation of gene expression;GO:0006285 base-excision repair, AP site formation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F861-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F868-1", "uniprot_id": [ { "id": "A0A9J7F868_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F868", "type": "external" } ], "mass": 109747.0, "length": 1035, "protein_name": "Collagen alpha-1(VI) chain", "gene_name": "Col6a1", "organism": "Hamster", "refseq_name": "collagen alpha-1(VI) chain", "refseq_ac": [ { "id": "XP_003500605", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500605", "type": "external" } ], "gene_names_uniprotkb": "Col6a1", "gene_names_refseq": "Col6a1", "protein_names_uniprotkb": "Collagen alpha-1(VI) chain", "protein_names_refseq": "collagen alpha-1(VI) chain", "tax_id": 10029, "disease": "", "pathway": " (cge:100755078)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613799.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Collagen VI acts as a cell-binding protein., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0005783 endoplasmic reticulum;GO:0005589 collagen type VI trimer", "go_biological_process": "GO:0007155 cell adhesion;GO:0030154 cell differentiation;GO:0009314 response to radiation;GO:0009888 tissue development;GO:0009653 anatomical structure morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F868-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F876-1", "uniprot_id": [ { "id": "A0A9J7F876_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F876", "type": "external" } ], "mass": 101348.0, "length": 903, "protein_name": "ATP-dependent DNA helicase DDX11", "gene_name": "Ddx11", "organism": "Hamster", "refseq_name": "ATP-dependent DNA helicase DDX11 isoform X2", "refseq_ac": [ { "id": "XP_027253583", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253583", "type": "external" } ], "gene_names_uniprotkb": "Ddx11", "gene_names_refseq": "Ddx11", "protein_names_uniprotkb": "ATP-dependent DNA helicase DDX11; 5.6.2.3; DEAD/H-box protein 11; DNA 5'-3' helicase DDX11", "protein_names_refseq": "ATP-dependent DNA helicase DDX11 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756953)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding", "go_cellular_component": "GO:0000922 spindle pole;GO:0005730 nucleolus;GO:0005813 centrosome;GO:0030496 midbody", "go_biological_process": "GO:0006281 DNA repair;GO:0006351 DNA-templated transcription;GO:0006260 DNA replication;GO:0034085 establishment of sister chromatid cohesion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F876-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F8B1-1", "uniprot_id": [ { "id": "A0A9J7F8B1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F8B1", "type": "external" } ], "mass": 58601.0, "length": 512, "protein_name": "Serine--tRNA ligase, cytoplasmic", "gene_name": "Sars1", "organism": "Hamster", "refseq_name": "serine--tRNA ligase, cytoplasmic", "refseq_ac": [ { "id": "XP_003515309", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003515309", "type": "external" } ], "gene_names_uniprotkb": "Sars1", "gene_names_refseq": "Sars1", "protein_names_uniprotkb": "Serine--tRNA ligase, cytoplasmic; 6.1.1.11; Seryl-tRNA synthetase; Seryl-tRNA(Ser/Sec) synthetase", "protein_names_refseq": "serine--tRNA ligase, cytoplasmic", "tax_id": 10029, "disease": "", "pathway": " (cge:100689195)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003617654.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction: serine is first activated by ATP to form Ser-AMP and then transferred to the acceptor end of tRNA(Ser). Is probably also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec). In the nucleus, binds to the VEGFA core promoter and prevents MYC binding and transcriptional activation by MYC. Recruits SIRT2 to the VEGFA promoter, promoting deacetylation of histone H4 at 'Lys-16' (H4K16). Thereby, inhibits the production of VEGFA and sprouting angiogenesis mediated by VEGFA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.1.1.11", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.11", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004828 serine-tRNA ligase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0016525 negative regulation of angiogenesis;GO:1904046 negative regulation of vascular endothelial growth factor production;GO:0006434 seryl-tRNA aminoacylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F8B1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F8I8-1", "uniprot_id": [ { "id": "A0A9J7F8I8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F8I8", "type": "external" } ], "mass": 191663.0, "length": 1801, "protein_name": "SH3 and multiple ankyrin repeat domains protein 3", "gene_name": "LOC100755144", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: SH3 and multiple ankyrin repeat domains protein 3 isoform X2", "refseq_ac": [ { "id": "XP_027252098", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027252098", "type": "external" } ], "gene_names_uniprotkb": "LOC100755144", "gene_names_refseq": "LOC100755144", "protein_names_uniprotkb": "SH3 and multiple ankyrin repeat domains protein 3; Proline-rich synapse-associated protein 2; SPANK-2", "protein_names_refseq": "LOW QUALITY PROTEIN: SH3 and multiple ankyrin repeat domains protein 3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100755144)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027252098.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0097110 scaffold protein binding;GO:0035255 ionotropic glutamate receptor binding;GO:0098919 structural constituent of postsynaptic density;GO:0030160 synaptic receptor adaptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0014069 postsynaptic density;GO:0043197 dendritic spine;GO:0045211 postsynaptic membrane", "go_biological_process": "GO:1900451 positive regulation of glutamate receptor signaling pathway;GO:0099175 regulation of postsynapse organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F8I8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F8M1-1", "uniprot_id": [ { "id": "A0A9J7F8M1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F8M1", "type": "external" } ], "mass": 45627.0, "length": 429, "protein_name": "Hyaluronan and proteoglycan link protein 4", "gene_name": "Hapln4", "organism": "Hamster", "refseq_name": "hyaluronan and proteoglycan link protein 4 isoform X2", "refseq_ac": [ { "id": "XP_027250432", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250432", "type": "external" } ], "gene_names_uniprotkb": "Hapln4", "gene_names_refseq": "Hapln4", "protein_names_uniprotkb": "Hyaluronan and proteoglycan link protein 4; Brain link protein 2", "protein_names_refseq": "hyaluronan and proteoglycan link protein 4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100764042)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Essential for the proper localization of brevican (BCAN), mainly as a perineuronal nets (PNNs)-type deposition in the brainstem and cerebellum thereby playing a key role in the formation and structural organization of PNNs. Contributes to the formation and transmission of inhibitory GABAergic synapses between Purkinje cells and deep cerebellar nuclei neurons., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005540 hyaluronic acid binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0045202 synapse;GO:0072534 perineuronal net", "go_biological_process": "GO:0007155 cell adhesion;GO:0007417 central nervous system development;GO:0001501 skeletal system development;GO:0002052 positive regulation of neuroblast proliferation;GO:0010001 glial cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F8M1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F8T0-1", "uniprot_id": [ { "id": "A0A9J7F8T0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F8T0", "type": "external" } ], "mass": 150833.0, "length": 1386, "protein_name": "PAS domain-containing serine/threonine-protein kinase", "gene_name": "Pask", "organism": "Hamster", "refseq_name": "PAS domain-containing serine/threonine-protein kinase isoform X1", "refseq_ac": [ { "id": "XP_027253460", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253460", "type": "external" } ], "gene_names_uniprotkb": "Pask", "gene_names_refseq": "Pask", "protein_names_uniprotkb": "PAS domain-containing serine/threonine-protein kinase; 2.7.11.1", "protein_names_refseq": "PAS domain-containing serine/threonine-protein kinase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100771865)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Serine/threonine-protein kinase involved in energy homeostasis and protein translation. Phosphorylates EEF1A1, GYS1, PDX1 and RPS6. Probably plays a role under changing environmental conditions (oxygen, glucose, nutrition), rather than under standard conditions. Acts as a sensor involved in energy homeostasis: regulates glycogen synthase synthesis by mediating phosphorylation of GYS1, leading to GYS1 inactivation. May be involved in glucose-stimulated insulin production in pancreas and regulation of glucagon secretion by glucose in alpha cells; however such data require additional evidences. May play a role in regulation of protein translation by phosphorylating EEF1A1, leading to increase translation efficiency. May also participate in respiratory regulation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0008289 lipid binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0006355 regulation of DNA-templated transcription;GO:0045719 negative regulation of glycogen biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F8T0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F8V9-1", "uniprot_id": [ { "id": "A0A9J7F8V9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F8V9", "type": "external" } ], "mass": 58894.0, "length": 544, "protein_name": "Alkaline phosphatase", "gene_name": "LOC113833526", "organism": "Hamster", "refseq_name": "alkaline phosphatase, germ cell type-like", "refseq_ac": [ { "id": "XP_027251787", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251787", "type": "external" } ], "gene_names_uniprotkb": "LOC113833526", "gene_names_refseq": "LOC113833526", "protein_names_uniprotkb": "Alkaline phosphatase; 3.1.3.1", "protein_names_refseq": "alkaline phosphatase, germ cell type-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113833526)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027251787.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" } ], "go_molecular_function": "GO:0004035 alkaline phosphatase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0098552 side of membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F8V9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F8X2-1", "uniprot_id": [ { "id": "A0A9J7F8X2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F8X2", "type": "external" } ], "mass": 24964.0, "length": 225, "protein_name": "Nucleophosmin", "gene_name": "LOC100751264", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: nucleophosmin-like isoform X2", "refseq_ac": [ { "id": "XP_027250934", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250934", "type": "external" } ], "gene_names_uniprotkb": "LOC100751264", "gene_names_refseq": "LOC100751264", "protein_names_uniprotkb": "Nucleophosmin", "protein_names_refseq": "LOW QUALITY PROTEIN: nucleophosmin-like isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100751264)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027250934.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0003723 RNA binding;GO:0042393 histone binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0010824 regulation of centrosome duplication;GO:0000055 ribosomal large subunit export from nucleus;GO:0006338 chromatin remodeling;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0042273 ribosomal large subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F8X2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F8X4-1", "uniprot_id": [ { "id": "A0A9J7F8X4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F8X4", "type": "external" } ], "mass": 109034.0, "length": 981, "protein_name": "Calsyntenin-1", "gene_name": "Clstn1", "organism": "Hamster", "refseq_name": "calsyntenin-1 isoform X2", "refseq_ac": [ { "id": "XP_027254077", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254077", "type": "external" } ], "gene_names_uniprotkb": "Clstn1", "gene_names_refseq": "Clstn1", "protein_names_uniprotkb": "Calsyntenin-1", "protein_names_refseq": "calsyntenin-1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100771175)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; As intracellular fragment AlcICD, suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment (AICD), most probably by competing with AICD for APBB1-binding., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Postsynaptic adhesion molecule that binds to presynaptic neurexins to mediate both excitatory and inhibitory synapse formation. Promotes synapse development by acting as a cell adhesion molecule at the postsynaptic membrane, which associates with neurexin-alpha at the presynaptic membrane. Also functions as a cargo in axonal anterograde transport by acting as a molecular adapter that promotes KLC1 association with vesicles. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0009986 cell surface;GO:0045211 postsynaptic membrane;GO:0005789 endoplasmic reticulum membrane;GO:0043005 neuron projection", "go_biological_process": "GO:0051965 positive regulation of synapse assembly;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0050806 positive regulation of synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F8X4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F8Y6-1", "uniprot_id": [ { "id": "A0A9J7F8Y6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F8Y6", "type": "external" } ], "mass": 35306.0, "length": 318, "protein_name": "Mitochondrial coenzyme A transporter SLC25A42", "gene_name": "Slc25a42", "organism": "Hamster", "refseq_name": "mitochondrial coenzyme A transporter SLC25A42", "refseq_ac": [ { "id": "XP_003499182", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499182", "type": "external" } ], "gene_names_uniprotkb": "Slc25a42", "gene_names_refseq": "Slc25a42", "protein_names_uniprotkb": "Mitochondrial coenzyme A transporter SLC25A42; Solute carrier family 25 member 42", "protein_names_refseq": "mitochondrial coenzyme A transporter SLC25A42", "tax_id": 10029, "disease": "", "pathway": " (cge:100750759)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613716.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3',5'-diphosphate., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0055085 transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F8Y6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F922-1", "uniprot_id": [ { "id": "A0A9J7F922_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F922", "type": "external" } ], "mass": 30523.0, "length": 280, "protein_name": "Exosome complex component RRP43", "gene_name": "Exosc8", "organism": "Hamster", "refseq_name": "exosome complex component RRP43 isoform X1", "refseq_ac": [ { "id": "XP_016835913", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016835913", "type": "external" } ], "gene_names_uniprotkb": "Exosc8", "gene_names_refseq": "Exosc8", "protein_names_uniprotkb": "Exosome complex component RRP43; Exosome component 8; Ribosomal RNA-processing protein 43", "protein_names_refseq": "exosome complex component RRP43 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100769802)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 70 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615307.1) and transcript sequence (JI877439.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0035925 mRNA 3'-UTR AU-rich region binding;GO:0016787 hydrolase activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0000176 nuclear exosome (RNase complex);GO:0000177 cytoplasmic exosome (RNase complex);GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0071028 nuclear mRNA surveillance;GO:0034473 U1 snRNA 3'-end processing;GO:0034476 U5 snRNA 3'-end processing;GO:0016075 rRNA catabolic process;GO:0000467 exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F922-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O09185-1", "uniprot_id": [ { "id": "P53_CRIGR", "url": "https://www.uniprot.org/uniprot/O09185", "type": "external" } ], "mass": 43378.0, "length": 393, "protein_name": "Cellular tumor antigen p53", "gene_name": "TP53", "organism": "Hamster", "refseq_name": "cellular tumor antigen p53", "refseq_ac": [ { "id": "NP_001230905", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230905", "type": "external" } ], "gene_names_uniprotkb": "TP53; P53", "gene_names_refseq": "P53; Tp53", "protein_names_uniprotkb": "Cellular tumor antigen p53; Tumor suppressor p53", "protein_names_refseq": "Tumor suppressor p53; cellular tumor antigen p53; p53 tumor suppressor", "tax_id": 10029, "disease": "", "pathway": " (cge:100682525)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "9023109;9031625", "class_list": "", "function": "Multifunctional transcription factor that induces cell cycle arrest, DNA repair or apoptosis upon binding to its target DNA sequence. Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Negatively regulates cell division by controlling expression of a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its interaction with PPP1R13B/ASPP1 or TP53BP2/ASPP2 (By similarity). However, this activity is inhibited when the interaction with PPP1R13B/ASPP1 or TP53BP2/ASPP2 is displaced by PPP1R13L/iASPP (By similarity). In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seems to have an effect on cell-cycle regulation. Regulates the circadian clock by repressing CLOCK-BMAL1-mediated transcriptional activation of PER2., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "P97258;P97788;Q64397", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0031625 ubiquitin protein ligase binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0005507 copper ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006979 response to oxidative stress;GO:0043065 positive regulation of apoptotic process;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0051262 protein tetramerization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "O09185-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O35501-1", "uniprot_id": [ { "id": "HSPA9_CRIGR", "url": "https://www.uniprot.org/uniprot/O35501", "type": "external" } ], "mass": 73731.0, "length": 679, "protein_name": "Stress-70 protein, mitochondrial", "gene_name": "HSPA9", "organism": "Hamster", "refseq_name": "stress-70 protein, mitochondrial", "refseq_ac": [ { "id": "NP_001233758", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233758", "type": "external" } ], "gene_names_uniprotkb": "HSPA9", "gene_names_refseq": "GRP-75; Hspa9", "protein_names_uniprotkb": "Stress-70 protein, mitochondrial; 3.6.4.10; 75 kDa glucose-regulated protein; GRP-75; Heat shock 70 kDa protein 9", "protein_names_refseq": "70 kDa heat shock protein; 75 kDa glucose-regulated protein; Heat shock 70 kDa protein 9; heat shock 70kDa protein 9 (mortalin); heat shock protein 9; stress-70 protein, mitochondrial", "tax_id": 10029, "disease": "", "pathway": " (cge:100689405)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "9260887", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: U92313.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN09948069, SAMN09948070 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U92313.1., [RefSeq]; Mitochondrial chaperone that plays a key role in mitochondrial protein import, folding, and assembly. Plays an essential role in the protein quality control system, the correct folding of proteins, the re-folding of misfolded proteins, and the targeting of proteins for subsequent degradation. These processes are achieved through cycles of ATP binding, ATP hydrolysis, and ADP release, mediated by co-chaperones. In mitochondria, it associates with the TIM (translocase of the inner membrane) protein complex to assist in the import and folding of mitochondrial proteins (By similarity). Plays an important role in mitochondrial iron-sulfur cluster (ISC) biogenesis, interacts with and stabilizes ISC cluster assembly proteins FXN, NFU1, NFS1 and ISCU. Regulates erythropoiesis via stabilization of ISC assembly. Regulates mitochondrial calcium-dependent apoptosis by coupling two calcium channels, ITPR1 and VDAC1, at the mitochondria-associated endoplasmic reticulum (ER) membrane to facilitate calcium transport from the ER lumen to the mitochondria intermembrane space, providing calcium for the downstream calcium channel MCU, which releases it into the mitochondrial matrix (By similarity). Although primarily located in the mitochondria, it is also found in other cellular compartments. In the cytosol, it associates with proteins involved in signaling, apoptosis, or senescence. It may play a role in cell cycle regulation via its interaction with and promotion of degradation of TP53 (By similarity). May play a role in the control of cell proliferation and cellular aging (By similarity). Protects against reactive oxygen species (ROS) (By similarity). Extracellular HSPA9 plays a cytoprotective role by preventing cell lysis following immune attack by the membrane attack complex by disrupting formation of the complex (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0051082 unfolded protein binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0016226 iron-sulfur cluster assembly;GO:1902037 negative regulation of hematopoietic stem cell differentiation;GO:0030218 erythrocyte differentiation;GO:0006457 protein folding;GO:0036444 calcium import into the mitochondrion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "O35501-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O55036-1", "uniprot_id": [ { "id": "TERF1_CRIGR", "url": "https://www.uniprot.org/uniprot/O55036", "type": "external" } ], "mass": 50186.0, "length": 438, "protein_name": "Telomeric repeat-binding factor 1", "gene_name": "TERF1", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TERF1; TRF1", "gene_names_refseq": "", "protein_names_uniprotkb": "Telomeric repeat-binding factor 1; TTAGGG repeat-binding factor 1", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "9798685", "class_list": "", "function": "Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded 5'-TTAGGG-3' repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008301 DNA binding, bending;GO:0098505 G-rich strand telomeric DNA binding;GO:0008017 microtubule binding;GO:0042803 protein homodimerization activity;GO:0003691 double-stranded telomeric DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005819 spindle;GO:0000783 nuclear telomere cap complex", "go_biological_process": "GO:0051301 cell division;GO:0007004 telomere maintenance via telomerase;GO:0008156 negative regulation of DNA replication;GO:1905839 negative regulation of telomeric D-loop disassembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "O55036-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O55058-1", "uniprot_id": [ { "id": "FBLN4_CRIGR", "url": "https://www.uniprot.org/uniprot/O55058", "type": "external" } ], "mass": 49432.0, "length": 443, "protein_name": "EGF-containing fibulin-like extracellular matrix protein 2", "gene_name": "EFEMP2", "organism": "Hamster", "refseq_name": "EGF-containing fibulin-like extracellular matrix protein 2 precursor", "refseq_ac": [ { "id": "NP_001231778", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231778", "type": "external" } ], "gene_names_uniprotkb": "EFEMP2; FBLN4", "gene_names_refseq": "Efemp2; FBLN4; FIBL-4; Fibulin-4; H411", "protein_names_uniprotkb": "EGF-containing fibulin-like extracellular matrix protein 2; FIBL-4; Fibulin-4; Protein H411", "protein_names_refseq": "EGF containing fibulin extracellular matrix protein 2; EGF containing fibulin like extracellular matrix protein 2; EGF-containing fibulin-like extracellular matrix protein 2 precursor; Protein H411; epidermal growth factor-containing fibulin-like extracellular matrix protein 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100736553)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a crucial role in elastic fiber formation in tissue, and in the formation of ultrastructural connections between elastic laminae and smooth muscle cells in the aorta, therefore participates in terminal differentiation and maturation of smooth muscle cell (SMC) and in the mechanical properties and wall integrity maintenance of the aorta. In addition, is involved in the control of collagen fibril assembly in tissue throught proteolytic activation of LOX leading to cross- linking of collagen and elastin. Also promotes ELN coacervation and participates in the deposition of ELN coacervates on to microfibrils but also regulates ELN cross- linking through LOX interaction. Moreover adheres to the cells through heparin binding in a calcium-dependent manner and regulates vascularlar smooth muscle cells proliferation through angiotensin signaling., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008201 heparin binding;GO:0042803 protein homodimerization activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0031012 extracellular matrix;GO:0005604 basement membrane;GO:0001527 microfibril;GO:0071953 elastic fiber", "go_biological_process": "GO:1905609 positive regulation of smooth muscle cell-matrix adhesion;GO:0035904 aorta development;GO:0097084 vascular associated smooth muscle cell development;GO:0048251 elastic fiber assembly;GO:0060414 aorta smooth muscle tissue morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "O55058-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O55075-1", "uniprot_id": [ { "id": "CADH2_CRIGR", "url": "https://www.uniprot.org/uniprot/O55075", "type": "external" } ], "mass": 26234.0, "length": 238, "protein_name": "Cadherin-2", "gene_name": "CDH2", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "CDH2", "gene_names_refseq": "", "protein_names_uniprotkb": "Cadherin-2; N-cadherin; Neural cadherin", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell. Cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. Plays a role in cell-to-cell junction formation between pancreatic beta cells and neural crest stem (NCS) cells, promoting the formation of processes by NCS cells (By similarity). Required for proper neurite branching. Required for pre- and postsynaptic organization (By similarity). CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density. May promote axon outgrowth and motor fiber repair via DSP-mediated recruitment to outgrowth tips (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 3, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0045296 cadherin binding;GO:0008013 beta-catenin binding", "go_cellular_component": "GO:0048787 presynaptic active zone membrane;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005912 adherens junction;GO:0009986 cell surface", "go_biological_process": "GO:0016477 cell migration;GO:0000902 cell morphogenesis;GO:0098609 cell-cell adhesion;GO:0007416 synapse assembly;GO:0007043 cell-cell junction assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "O55075-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000010000000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O70523-1", "uniprot_id": [ { "id": "FXR1_CRIGR", "url": "https://www.uniprot.org/uniprot/O70523", "type": "external" } ], "mass": 69706.0, "length": 621, "protein_name": "RNA-binding protein FXR1", "gene_name": "FXR1", "organism": "Hamster", "refseq_name": "RNA-binding protein FXR1", "refseq_ac": [ { "id": "NP_001233685", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233685", "type": "external" } ], "gene_names_uniprotkb": "FXR1", "gene_names_refseq": "Fxr1", "protein_names_uniprotkb": "RNA-binding protein FXR1", "protein_names_refseq": "RNA-binding protein FXR1; fragile X-related protein", "tax_id": 10029, "disease": "", "pathway": " (cge:100689323)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "9642279", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: Y12837.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN04275174, SAMN04275175 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from Y12837.1., [RefSeq]; mRNA-binding protein that acts as a regulator of mRNAs translation and/or stability, and which is required for various processes, such as neurogenesis, muscle development and spermatogenesis. Specifically binds to AU-rich elements (AREs) in the 3'-UTR of target mRNAs. Promotes formation of some phase-separated membraneless compartment by undergoing liquid-liquid phase separation upon binding to AREs-containing mRNAs, leading to assemble mRNAs into cytoplasmic ribonucleoprotein granules that concentrate mRNAs with associated regulatory factors. Required to activate translation of stored mRNAs during late spermatogenesis: acts by undergoing liquid-liquid phase separation to assemble target mRNAs into cytoplasmic ribonucleoprotein granules that recruit translation initiation factor EIF4G3 to activate translation of stored mRNAs in late spermatids (By similarity). Promotes translation of MYC transcripts by recruiting the eIF4F complex to the translation start site. Acts as a negative regulator of inflammation in response to IL19 by promoting destabilization of pro-inflammatory transcripts (By similarity). Also acts as an inhibitor of inflammation by binding to TNF mRNA, decreasing TNF protein production. Acts as a negative regulator of AMPA receptor GRIA2/GluA2 synthesis during long-lasting synaptic potentiation of hippocampal neurons by binding to GRIA2/GluA2 mRNA, thereby inhibiting its translation. Regulates proliferation of adult neural stem cells by binding to CDKN1A mRNA and promoting its expression. Acts as a regulator of sleep and synaptic homeostasis by regulating translation of transcripts in neurons. Required for embryonic and postnatal development of muscle tissue by undergoing liquid-liquid phase separation to assemble target mRNAs into cytoplasmic ribonucleoprotein granules (By similarity). Involved in the nuclear pore complex localization to the nuclear envelope by preventing cytoplasmic aggregation of nucleoporins: acts by preventing ectopic phase separation of nucleoporins in the cytoplasm via a microtubule-dependent mechanism (By similarity). Plays a role in the stabilization of PKP2 mRNA and therefore protein abundance, via its interaction with PKP3 (By similarity). May also do the same for PKP2, PKP3 and DSP via its interaction with PKP1 (By similarity). Forms a cytoplasmic messenger ribonucleoprotein (mRNP) network by packaging long mRNAs, serving as a scaffold that recruits proteins and signaling molecules. This network facilitates signaling reactions by maintaining proximity between kinases and substrates, crucial for processes like actomyosin reorganization (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0045182 translation regulator activity;GO:0033592 RNA strand annealing activity", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0030424 axon;GO:0043197 dendritic spine;GO:0036464 cytoplasmic ribonucleoprotein granule;GO:0005840 ribosome", "go_biological_process": "GO:0045187 regulation of circadian sleep/wake cycle, sleep;GO:1900272 negative regulation of long-term synaptic potentiation;GO:0010608 post-transcriptional regulation of gene expression;GO:0032720 negative regulation of tumor necrosis factor production;GO:0050728 negative regulation of inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "O70523-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P00494-1", "uniprot_id": [ { "id": "HPRT_CRIGR", "url": "https://www.uniprot.org/uniprot/P00494", "type": "external" } ], "mass": 24644.0, "length": 218, "protein_name": "Hypoxanthine-guanine phosphoribosyltransferase", "gene_name": "HPRT1", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "HPRT1; HPRT", "gene_names_refseq": "", "protein_names_uniprotkb": "Hypoxanthine-guanine phosphoribosyltransferase; 2.4.2.8; HGPRTase; HGPRT", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "1383700;2004774;6294614", "class_list": "", "function": "Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q80XX0", "ec_number_list": [ { "id": "2.4.2.8", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.8", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0042802 identical protein binding;GO:0000166 nucleotide binding;GO:0004422 hypoxanthine phosphoribosyltransferase activity;GO:0052657 guanine phosphoribosyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0046040 IMP metabolic process;GO:0043103 hypoxanthine salvage;GO:0032264 IMP salvage;GO:0045964 positive regulation of dopamine metabolic process;GO:0006166 purine ribonucleoside salvage", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P00494-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P04773-1", "uniprot_id": [ { "id": "GLNA_CRIGR", "url": "https://www.uniprot.org/uniprot/P04773", "type": "external" } ], "mass": 42320.0, "length": 373, "protein_name": "Glutamine synthetase", "gene_name": "GLUL", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "GLUL", "gene_names_refseq": "", "protein_names_uniprotkb": "Glutamine synthetase; 2.3.1.225; 6.3.1.2; GS; Glutamate--ammonia ligase; Palmitoyltransferase GLUL", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100689337)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "2868445", "class_list": "", "function": "Glutamine synthetase that catalyzes the ATP-dependent conversion of glutamate and ammonia to glutamine. Its role depends on tissue localization: in the brain, it regulates the levels of toxic ammonia and converts neurotoxic glutamate to harmless glutamine, whereas in the liver, it is one of the enzymes responsible for the removal of ammonia. Plays a key role in ammonium detoxification during erythropoiesis: the glutamine synthetase activity is required to remove ammonium generated by porphobilinogen deaminase (HMBS) during heme biosynthesis to prevent ammonium accumulation and oxidative stress (By similarity). Essential for proliferation of fetal skin fibroblasts (By similarity). Independently of its glutamine synthetase activity, required for endothelial cell migration during vascular development (By similarity). Involved in angiogenesis by regulating membrane localization and activation of the GTPase RHOJ, possibly by promoting RHOJ palmitoylation. May act as a palmitoyltransferase for RHOJ: able to autopalmitoylate and then transfer the palmitoyl group to RHOJ. Plays a role in ribosomal 40S subunit biogenesis. Through the interaction with BEST2, inhibits BEST2 channel activity by affecting the gating at the aperture in the absence of intracellular L-glutamate, but sensitizes BEST2 to intracellular L-glutamate, which promotes the opening of BEST2 and thus relieves its inhibitory effect on BEST2 (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9EQP8", "ec_number_list": [ { "id": "2.3.1.225", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.225", "type": "external" }, { "id": "6.3.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.1.2", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0019706 protein-cysteine S-palmitoyltransferase activity;GO:0004356 glutamine synthetase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0001525 angiogenesis;GO:0045648 positive regulation of erythrocyte differentiation;GO:0097275 intracellular ammonium homeostasis;GO:1903670 regulation of sprouting angiogenesis;GO:0006542 glutamine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P04773-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P07156-1", "uniprot_id": [ { "id": "HMGB1_CRIGR", "url": "https://www.uniprot.org/uniprot/P07156", "type": "external" } ], "mass": 20904.0, "length": 180, "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "HMGB1; HMG-1; HMG1", "gene_names_refseq": "", "protein_names_uniprotkb": "High mobility group protein B1; HMG-1; High mobility group protein 1", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "3601666;8346022", "class_list": "", "function": "In the cytoplasm proposed to dissociate the BECN1:BCL2 complex via competitive interaction with BECN1 leading to autophagy activation. Can protect BECN1 and ATG5 from calpain-mediated cleavage and thus proposed to control their proautophagic and proapoptotic functions and to regulate the extent and severity of inflammation-associated cellular injury. In myeloid cells has a protective role against endotoxemia and bacterial infection by promoting autophagy. Involved in endosomal translocation and activation of TLR9 in response to CpG-DNA in macrophages., [UniProtKB, UniProtKB, UniProtKB]; In the extracellular compartment (following either active secretion or passive release) involved in regulation of the inflammatory response. Fully reduced HGMB1 (which subsequently gets oxidized after release) in association with CXCL12 mediates the recruitment of inflammatory cells during the initial phase of tissue injury; the CXCL12:HMGB1 complex triggers CXCR4 homodimerization. Induces the migration of monocyte-derived immature dendritic cells and seems to regulate adhesive and migratory functions of neutrophils implicating AGER/RAGE and ITGAM. Can bind to various types of DNA and RNA including microbial unmethylated CpG-DNA to enhance the innate immune response to nucleic acids. Proposed to act in promiscuous DNA/RNA sensing which cooperates with subsequent discriminative sensing by specific pattern recognition receptors. Promotes extracellular DNA-induced AIM2 inflammasome activation implicating AGER/RAGE. Disulfide HMGB1 binds to transmembrane receptors, such as AGER/RAGE, TLR2, TLR4 and probably TREM1, thus activating their signal transduction pathways. Mediates the release of cytokines/chemokines such as TNF, IL-1, IL-6, IL-8, CCL2, CCL3, CCL4 and CXCL10. Promotes secretion of interferon-gamma by macrophage-stimulated natural killer (NK) cells in concert with other cytokines like IL-2 or IL-12. TLR4 is proposed to be the primary receptor promoting macrophage activation and signaling through TLR4 seems to implicate LY96/MD-2. In bacterial LPS- or LTA-mediated inflammatory responses binds to the endotoxins and transfers them to CD14 for signaling to the respective TLR4:LY96 and TLR2 complexes. Contributes to tumor proliferation by association with ACER/RAGE. Can bind to IL1-beta and signals through the IL1R1:IL1RAP receptor complex. Binding to class A CpG activates cytokine production in plasmacytoid dendritic cells implicating TLR9, MYD88 and AGER/RAGE and can activate autoreactive B cells. Via HMGB1-containing chromatin immune complexes may also promote B cell responses to endogenous TLR9 ligands through a B-cell receptor (BCR)-dependent and ACER/RAGE-independent mechanism. Inhibits phagocytosis of apoptotic cells by macrophages; the function is dependent on poly-ADP-ribosylation and involves binding to phosphatidylserine on the cell surface of apoptotic cells. In adaptive immunity may be involved in enhancing immunity through activation of effector T-cells and suppression of regulatory T (TReg) cells. In contrast, without implicating effector or regulatory T-cells, required for tumor infiltration and activation of T-cells expressing the lymphotoxin LTA:LTB heterotrimer thus promoting tumor malignant progression. Also reported to limit proliferation of T-cells. Released HMGB1:nucleosome complexes formed during apoptosis can signal through TLR2 to induce cytokine production. Involved in induction of immunological tolerance by apoptotic cells; its pro-inflammatory activities when released by apoptotic cells are neutralized by reactive oxygen species (ROS)-dependent oxidation specifically on Cys-106. During macrophage activation by activated lymphocyte-derived self apoptotic DNA (ALD-DNA) promotes recruitment of ALD-DNA to endosomes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Multifunctional redox sensitive protein with various roles in different cellular compartments. In the nucleus is one of the major chromatin-associated non-histone proteins and acts as a DNA chaperone involved in replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair and genome stability. Proposed to be an universal biosensor for nucleic acids. Promotes host inflammatory response to sterile and infectious signals and is involved in the coordination and integration of innate and adaptive immune responses. In the cytoplasm functions as a sensor and/or chaperone for immunogenic nucleic acids implicating the activation of TLR9-mediated immune responses, and mediates autophagy. Acts as a danger-associated molecular pattern (DAMP) molecule that amplifies immune responses during tissue injury. Released to the extracellular environment can bind DNA, nucleosomes, IL-1 beta, CXCL12, AGER isoform 2/sRAGE, lipopolysaccharide (LPS) and lipoteichoic acid (LTA), and activates cells through engagement of multiple surface receptors. In the extracellular compartment fully reduced HMGB1 (released by necrosis) acts as a chemokine, disulfide HMGB1 (actively secreted) as a cytokine, and sulfonyl HMGB1 (released from apoptotic cells) promotes immunological tolerance. Has proangiogenic activity. May be involved in platelet activation. Binds to phosphatidylserine and phosphatidylethanolamide. Bound to RAGE mediates signaling for neuronal outgrowth. May play a role in accumulation of expanded polyglutamine (polyQ) proteins., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Nuclear functions are attributed to fully reduced HGMB1. Associates with chromatin and binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA, DNA-containing cruciforms or bent structures, supercoiled DNA and ZDNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters by enhancing transcription factor binding and/or bringing distant regulatory sequences into close proximity. May be involved in nucleotide excision repair (NER), mismatch repair (MMR) and base excision repair (BER) pathways, and double strand break repair such as non-homologous end joining (NHEJ). Involved in V(D)J recombination by acting as a cofactor of the RAG complex: acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). In vitro can displace histone H1 from highly bent DNA. Can restructure the canonical nucleosome leading to relaxation of structural constraints for transcription factor-binding. Enhances binding of sterol regulatory element-binding proteins (SREBPs) such as SREBF1 to their cognate DNA sequences and increases their transcriptional activities. Facilitates binding of TP53 to DNA. May be involved in mitochondrial quality control and autophagy in a transcription-dependent fashion implicating HSPB1. Can modulate the activity of the telomerase complex and may be involved in telomere maintenance., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005634 nucleus;GO:0005768 endosome;GO:0005886 plasma membrane;GO:0000793 condensed chromosome", "go_biological_process": "GO:0002840 regulation of T cell mediated immune response to tumor cell;GO:0017055 negative regulation of RNA polymerase II transcription preinitiation complex assembly;GO:0006310 DNA recombination;GO:0006935 chemotaxis;GO:0006954 inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P07156-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P09445-1", "uniprot_id": [ { "id": "EF2_CRIGR", "url": "https://www.uniprot.org/uniprot/P09445", "type": "external" } ], "mass": 95297.0, "length": 858, "protein_name": "Elongation factor 2", "gene_name": "EEF2", "organism": "Hamster", "refseq_name": "elongation factor 2", "refseq_ac": [ { "id": "NP_001230968", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230968", "type": "external" } ], "gene_names_uniprotkb": "EEF2; EF2", "gene_names_refseq": "EF-2; Eef2; Ef2", "protein_names_uniprotkb": "Elongation factor 2; 3.6.5.-; EF-2", "protein_names_refseq": "elongation factor 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100689051)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "24140707;2834376;3014523;7559470", "class_list": "", "function": "Catalyzes the GTP-dependent ribosomal translocation step during translation elongation (PubMed:7559470). During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively (PubMed:7559470). Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (PubMed:7559470)., [UniProtKB, PubMed]; EF2 diphthamide controls the selective translation of IRES-dependent protein targets XIAP and FGF2, critical for cell survival under conditions of oxidative stress., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P05086;Q60423", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0003746 translation elongation factor activity;GO:0043022 ribosome binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006414 translational elongation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P09445-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P11414-1", "uniprot_id": [ { "id": "RPB1_CRIGR", "url": "https://www.uniprot.org/uniprot/P11414", "type": "external" } ], "mass": 217206.0, "length": 1970, "protein_name": "DNA-directed RNA polymerase II subunit RPB1", "gene_name": "POLR2A", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "POLR2A", "gene_names_refseq": "", "protein_names_uniprotkb": "DNA-directed RNA polymerase II subunit RPB1; 2.7.7.48; 2.7.7.6; 3'-5' exoribonuclease; 3.1.13.-; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase III largest subunit; RNA polymerase II subunit B1; RNA-directed RNA polymerase II subunit RPB1", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100689016)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "11674999;3122024;34526721;9272869", "class_list": "", "function": "Catalytic core component of RNA polymerase II (Pol II), a DNA-dependent RNA polymerase which synthesizes mRNA precursors and many functional non-coding RNAs using the four ribonucleoside triphosphates as substrates (By similarity). Pol II-mediated transcription cycle proceeds through transcription initiation, transcription elongation and transcription termination stages. During transcription initiation, Pol II pre-initiation complex (PIC) is recruited to DNA promoters, with focused-type promoters containing either the initiator (Inr) element, or the TATA-box found in cell-type specific genes and dispersed-type promoters that often contain hypomethylated CpG islands usually found in housekeeping genes. Once the polymerase has escaped from the promoter it enters the elongation phase during which RNA is actively polymerized, based on complementarity with the template DNA strand. Transcription termination involves the release of the RNA transcript and polymerase from the DNA (By similarity). Forms Pol II active center together with the second largest subunit POLR2B/RPB2. Appends one nucleotide at a time to the 3' end of the nascent RNA, with POLR2A/RPB1 most likely contributing a Mg(2+)-coordinating DxDGD motif, and POLR2B/RPB2 participating in the coordination of a second Mg(2+) ion and providing lysine residues believed to facilitate Watson-Crick base pairing between the incoming nucleotide and template base. Typically, Mg(2+) ions direct a 5' nucleoside triphosphate to form a phosphodiester bond with the 3' hydroxyl of the preceding nucleotide of the nascent RNA, with the elimination of pyrophosphate. The reversible pyrophosphorolysis can occur at high pyrophosphate concentrations (By similarity). Can proofread the nascent RNA transcript by means of a 3' -> 5' exonuclease activity. If a ribonucleotide is mis-incorporated, backtracks along the template DNA and cleaves the phosphodiester bond releasing the mis-incorporated 5'-ribonucleotide (By similarity). Through its unique C-terminal domain (CTD, 52 heptapeptide tandem repeats) serves as a platform for assembly of factors that regulate transcription initiation, elongation and termination. CTD phosphorylation on Ser-5 mediates Pol II promoter escape, whereas phosphorylation on Ser-2 is required for Pol II pause release during transcription elongation and further pre-mRNA processing. Additionally, the regulation of gene expression levels depends on the balance between methylation and acetylation levels of the CTD-lysines. Initiation or early elongation steps of transcription of growth-factor-induced immediate early genes are regulated by the acetylation status of the CTD. Methylation and dimethylation have a repressive effect on target genes expression. Cooperates with mRNA splicing machinery in co-transcriptional 5'-end capping and co-transcriptional splicing of pre-mRNA (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; RNA-dependent RNA polymerase that catalyzes the extension of a non-coding RNA (ncRNA) at the 3'-end using the four ribonucleoside triphosphates as substrates. An internal ncRNA sequence near the 3'-end serves as a template in a single-round Pol II-mediated RNA polymerization reaction. May decrease the stability of ncRNAs that repress Pol II-mediated gene transcription., [UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 44, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q76M93", "ec_number_list": [ { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "3.1.13.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.-", "type": "external" }, { "id": "2.7.7.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.48", "type": "external" } ], "go_molecular_function": "GO:0003968 RNA-directed RNA polymerase activity;GO:0003677 DNA binding;GO:0016787 hydrolase activity;GO:0046872 metal ion binding;GO:1990841 promoter-specific chromatin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005694 chromosome;GO:0005665 RNA polymerase II, core complex", "go_biological_process": "GO:0033120 positive regulation of RNA splicing;GO:0006366 transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P11414-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P14607-1", "uniprot_id": [ { "id": "DDIT3_CRIGR", "url": "https://www.uniprot.org/uniprot/P14607", "type": "external" } ], "mass": 18831.0, "length": 168, "protein_name": "DNA damage-inducible transcript 3 protein", "gene_name": "DDIT3", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "DDIT3; CHOP10; CHOP; GADD153", "gene_names_refseq": "", "protein_names_uniprotkb": "DNA damage-inducible transcript 3 protein; C/EBP zeta; C/EBP-homologous protein 10; C/EBP-homologous protein; CCAAT/enhancer-binding protein homologous protein; CHOP-10; CHOP; DDIT-3; Growth arrest and DNA-damage-inducible protein GADD153", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "2573827", "class_list": "", "function": "Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer-binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression of C/EBP regulated genes. Positively regulates the transcription of TRIB3, IL6, IL8, IL23, TNFRSF10B/DR5, PPP1R15A/GADD34, BBC3/PUMA, BCL2L11/BIM and ERO1L. Negatively regulates; expression of BCL2 and MYOD1, ATF4-dependent transcriptional activation of asparagine synthetase (ASNS), CEBPA-dependent transcriptional activation of hepcidin (HAMP) and CEBPB-mediated expression of peroxisome proliferator-activated receptor gamma (PPARG). Inhibits the canonical Wnt signaling pathway by binding to TCF7L2/TCF4, impairing its DNA-binding properties and repressing its transcriptional activity. Plays a regulatory role in the inflammatory response through the induction of caspase-11 (CASP4/CASP11) which induces the activation of caspase-1 (CASP1) and both these caspases increase the activation of pro-IL1B to mature IL1B which is involved in the inflammatory response (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0046982 protein heterodimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0036488 CHOP-C/EBP complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:1990622 CHOP-ATF3 complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0010506 regulation of autophagy;GO:0042594 response to starvation;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P14607-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P17244-1", "uniprot_id": [ { "id": "G3P_CRIGR", "url": "https://www.uniprot.org/uniprot/P17244", "type": "external" } ], "mass": 35748.0, "length": 333, "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "GAPDH", "organism": "Hamster", "refseq_name": "glyceraldehyde-3-phosphate dehydrogenase", "refseq_ac": [ { "id": "NP_001231783", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231783", "type": "external" } ], "gene_names_uniprotkb": "GAPDH; GAPD", "gene_names_refseq": "GAPD; Gapdh", "protein_names_uniprotkb": "Glyceraldehyde-3-phosphate dehydrogenase; 1.2.1.12; 2.6.99.-; GAPDH; Peptidyl-cysteine S-nitrosylase GAPDH", "protein_names_refseq": "Peptidyl-cysteine S-nitrosylase GAPDH; glyceraldehyde-3-phosphate dehydrogenase", "tax_id": 10029, "disease": "", "pathway": " (cge:100736557)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "2349105", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: X52123.1, JI870486.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN04275174, SAMN04275175 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X52123.1., [RefSeq]; Catalyzes the conversion of D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate in glycolysis and the reverse reaction in gluconeogenesis. Also shows nitrosylase activity, thereby playing a role in nuclear functions (By similarity). Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity). Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. Also plays a role in innate immunity by promoting TNF-induced NF-kappa-B activation and type I interferon production, via interaction with TRAF2 and TRAF3, respectively (By similarity). Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 15, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.2.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.12", "type": "external" }, { "id": "2.6.99.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.99.-", "type": "external" } ], "go_molecular_function": "GO:0008017 microtubule binding;GO:0051287 NAD binding;GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity;GO:0035605 peptidyl-cysteine S-nitrosylase activity;GO:0050661 NADP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0015630 microtubule cytoskeleton;GO:0097452 GAIT complex", "go_biological_process": "GO:0006417 regulation of translation;GO:0045087 innate immune response;GO:0051402 neuron apoptotic process;GO:0006094 gluconeogenesis;GO:0043123 positive regulation of canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P17244-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P17852-1", "uniprot_id": [ { "id": "ITA3_CRIGR", "url": "https://www.uniprot.org/uniprot/P17852", "type": "external" } ], "mass": 116456.0, "length": 1051, "protein_name": "Integrin alpha-3", "gene_name": "ITGA3", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ITGA3", "gene_names_refseq": "", "protein_names_uniprotkb": "Integrin alpha-3; CD49 antigen-like family member C; GAPB3; Galactoprotein B3; VLA-3 subunit alpha", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "1691184;1946438", "class_list": "", "function": "Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration., [UniProtKB, UniProtKB]", "predicted_glycosites": 12, "predicted_n_glycosites": 12, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 12, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0046872 metal ion binding;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0009897 external side of plasma membrane;GO:0031527 filopodium membrane;GO:0008305 integrin complex", "go_biological_process": "GO:0048731 system development;GO:0007229 integrin-mediated signaling pathway;GO:0030154 cell differentiation;GO:0007160 cell-matrix adhesion;GO:0033627 cell adhesion mediated by integrin", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P17852-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000010000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P19378-1", "uniprot_id": [ { "id": "HSP7C_CRIGR", "url": "https://www.uniprot.org/uniprot/P19378", "type": "external" } ], "mass": 70805.0, "length": 646, "protein_name": "Heat shock cognate 71 kDa protein", "gene_name": "HSPA8", "organism": "Hamster", "refseq_name": "heat shock cognate 71 kDa protein", "refseq_ac": [ { "id": "NP_001233658", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233658", "type": "external" } ], "gene_names_uniprotkb": "HSPA8; HSC70", "gene_names_refseq": "HSC70; Hspa8", "protein_names_uniprotkb": "Heat shock cognate 71 kDa protein; 3.6.4.10; Heat shock 70 kDa protein 8", "protein_names_refseq": "Heat shock 70 kDa protein 8; heat shock 70kDa protein 8; heat shock cognate 71 kDa protein; heat shock protein 8", "tax_id": 10029, "disease": "", "pathway": " (cge:100689472)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "1975944", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: M34561.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN04275174, SAMN04275175 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M34561.1., [RefSeq]; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, chaperone-mediated autophagy, activation of proteolysis of misfolded proteins, formation and dissociation of protein complexes, and antigen presentation. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The co-chaperones have been shown to not only regulate different steps of the ATPase cycle of HSP70, but they also have an individual specificity such that one co-chaperone may promote folding of a substrate while another may promote degradation. The affinity of HSP70 for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins. However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins. HSP70 goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release. The HSP70-associated co-chaperones are of three types: J-domain co-chaperones HSP40s (stimulate ATPase hydrolysis by HSP70), the nucleotide exchange factors (NEF) such as BAG1/2/3 (facilitate conversion of HSP70 from the ADP-bound to the ATP-bound state thereby promoting substrate release), and the TPR domain chaperones such as HOPX and STUB1. Plays a critical role in mitochondrial import, delivers preproteins to the mitochondrial import receptor TOMM70. Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. Binds bacterial lipopolysaccharide (LPS) and mediates LPS-induced inflammatory response, including TNF secretion by monocytes. Substrate recognition component in chaperone-mediated autophagy (CMA), a selective protein degradation process that mediates degradation of proteins with a -KFERQ motif: HSPA8/HSC70 specifically recognizes and binds cytosolic proteins bearing a -KFERQ motif and promotes their recruitment to the surface of the lysosome where they bind to lysosomal protein LAMP2. KFERQ motif-containing proteins are eventually transported into the lysosomal lumen where they are degraded. In conjunction with LAMP2, facilitates MHC class II presentation of cytoplasmic antigens by guiding antigens to the lysosomal membrane for interaction with LAMP2 which then elicits MHC class II presentation of peptides to the cell membrane. Participates in the ER-associated degradation (ERAD) quality control pathway in conjunction with J domain-containing co-chaperones and the E3 ligase STUB1. It is recruited to clathrin-coated vesicles through its interaction with DNAJC6 leading to activation of HSPA8/HSC70 ATPase activity and therefore uncoating of clathrin-coated vesicles (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0030674 protein-macromolecule adaptor activity;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005886 plasma membrane;GO:0005681 spliceosomal complex;GO:0005765 lysosomal membrane", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006397 mRNA processing;GO:0045892 negative regulation of DNA-templated transcription;GO:0008380 RNA splicing;GO:0072318 clathrin coat disassembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P19378-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P20944-1", "uniprot_id": [ { "id": "CD44_CRIGR", "url": "https://www.uniprot.org/uniprot/P20944", "type": "external" } ], "mass": 39775.0, "length": 362, "protein_name": "CD44 antigen", "gene_name": "CD44", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "CD44", "gene_names_refseq": "", "protein_names_uniprotkb": "CD44 antigen; ECMR-III; Extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Hermes antigen; Hyaluronate receptor; PGP-1; PGP-I; Phagocytic glycoprotein 1; Phagocytic glycoprotein I", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "1694723", "class_list": "", "function": "Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment. Participates thereby in a wide variety of cellular functions including the activation, recirculation and homing of T-lymphocytes, hematopoiesis, inflammation and response to bacterial infection. Engages, through its ectodomain, extracellular matrix components such as hyaluronan/HA, collagen, growth factors, cytokines or proteases and serves as a platform for signal transduction by assembling, via its cytoplasmic domain, protein complexes containing receptor kinases and membrane proteases. Such effectors include PKN2, the RhoGTPases RAC1 and RHOA, Rho-kinases and phospholipase C that coordinate signaling pathways promoting calcium mobilization and actin-mediated cytoskeleton reorganization essential for cell migration and adhesion. Upon interaction with LGALS9 ligand, activates downstream signaling components including LCK, ERK and MAPK to promotes NK cell activation., [UniProtKB, UniProtKB]", "predicted_glycosites": 8, "predicted_n_glycosites": 7, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005540 hyaluronic acid binding;GO:0004896 cytokine receptor activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0048731 system development;GO:0006954 inflammatory response;GO:0007155 cell adhesion;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:2000392 regulation of lamellipodium morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P20944-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000011001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P23174-1", "uniprot_id": [ { "id": "MDR3_CRIGR", "url": "https://www.uniprot.org/uniprot/P23174", "type": "external" } ], "mass": 140866.0, "length": 1281, "protein_name": "Phosphatidylcholine translocator ABCB4", "gene_name": "ABCB4", "organism": "Hamster", "refseq_name": "phosphatidylcholine translocator ABCB4", "refseq_ac": [ { "id": "NP_001230916", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230916", "type": "external" } ], "gene_names_uniprotkb": "ABCB4; PGP3; PGY3", "gene_names_refseq": "Abcb4; PGP3; PGY3", "protein_names_uniprotkb": "Phosphatidylcholine translocator ABCB4; 7.6.2.1; ATP-binding cassette sub-family B member 4; Multidrug resistance protein 3; P-glycoprotein 3", "protein_names_refseq": "ATP-binding cassette sub-family B member 4; Multidrug resistance protein 3; P-glycoprotein 3; phosphatidylcholine translocator ABCB4", "tax_id": 10029, "disease": "", "pathway": " (cge:100682535)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "1685679", "class_list": "", "function": "Energy-dependent phospholipid efflux translocator that acts as a positive regulator of biliary lipid secretion. Functions as a floppase that translocates specifically phosphatidylcholine (PC) from the inner to the outer leaflet of the canalicular membrane bilayer into the canaliculi of hepatocytes. Translocation of PC makes the biliary phospholipids available for extraction into the canaliculi lumen by bile salt mixed micelles and therefore protects the biliary tree from the detergent activity of bile salts. Plays a role in the recruitment of phosphatidylcholine (PC), phosphatidylethanolamine (PE) and sphingomyelin (SM) molecules to nonraft membranes and to further enrichment of SM and cholesterol in raft membranes in hepatocytes. Required for proper phospholipid bile formation. Indirectly involved in cholesterol efflux activity from hepatocytes into the canalicular lumen in the presence of bile salts in an ATP-dependent manner. May promote biliary phospholipid secretion as canaliculi-containing vesicles from the canalicular plasma membrane. In cooperation with ATP8B1, functions to protect hepatocytes from the deleterious detergent activity of bile salts. Does not confer multidrug resistance., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "7.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.1", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0042626 ATPase-coupled transmembrane transporter activity;GO:0016887 ATP hydrolysis activity;GO:0015421 ABC-type oligopeptide transporter activity;GO:0090554 phosphatidylcholine floppase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005743 mitochondrial inner membrane;GO:0005886 plasma membrane;GO:0045121 membrane raft;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0055088 lipid homeostasis;GO:0061092 positive regulation of phospholipid translocation;GO:0032376 positive regulation of cholesterol transport;GO:0032782 bile acid secretion;GO:1901557 response to fenofibrate", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P23174-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38982-1", "uniprot_id": [ { "id": "RSSA_CRIGR", "url": "https://www.uniprot.org/uniprot/P38982", "type": "external" } ], "mass": 32881.0, "length": 295, "protein_name": "Small ribosomal subunit protein uS2", "gene_name": "Rpsa", "organism": "Hamster", "refseq_name": "small ribosomal subunit protein uS2", "refseq_ac": [ { "id": "NP_001230962", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230962", "type": "external" } ], "gene_names_uniprotkb": "Rpsa; LAMR1", "gene_names_refseq": "37lrp; 67lr; Lamr1; Lamr; Lbp/p40; Lrp/lr; Rpsa", "protein_names_uniprotkb": "Small ribosomal subunit protein uS2; 37 kDa laminin receptor precursor; 37/67 kDa laminin receptor; 37LRP; 40S ribosomal protein SA; 67 kDa laminin receptor; 67LR; LBP/p40; LRP/LR; LamR; Laminin receptor 1; Laminin-binding protein precursor p40", "protein_names_refseq": "34/67 kDa laminin receptor; 37 kDa laminin receptor; 37/67 kDa laminin receptor; 37LRP; 40S ribosomal protein SA; 67 kDa laminin receptor; 67LR; LRP/LR; laminin receptor 1; laminin-binding protein precursor p40; small ribosomal subunit protein uS2", "tax_id": 10029, "disease": "", "pathway": " (cge:100689045)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "1385835;7669786;8917612", "class_list": "", "function": "Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, Sindbis virus, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA (By similarity)., [UniProtKB, HAMAP, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043236 laminin binding;GO:0001618 virus receptor activity;GO:0005055 laminin receptor activity;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0006412 translation;GO:0000028 ribosomal small subunit assembly", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P38982-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P46633-1", "uniprot_id": [ { "id": "HS90A_CRIGR", "url": "https://www.uniprot.org/uniprot/P46633", "type": "external" } ], "mass": 84849.0, "length": 733, "protein_name": "Heat shock protein HSP 90-alpha", "gene_name": "HSP90AA1", "organism": "Hamster", "refseq_name": "heat shock protein HSP 90-alpha", "refseq_ac": [ { "id": "NP_001233750", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233750", "type": "external" } ], "gene_names_uniprotkb": "HSP90AA1; HSP90A; HSPCA", "gene_names_refseq": "HSPCA; Hsp90aa1; Hsp90a", "protein_names_uniprotkb": "Heat shock protein HSP 90-alpha; 3.6.4.10", "protein_names_refseq": "heat shock protein 90A; heat shock protein 90kDa alpha (cytosolic), class A member 1; heat shock protein HSP 90-alpha", "tax_id": 10029, "disease": "", "pathway": " (cge:100689397)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interaction with various co-chaperone proteins or complexes, that act as adapters, simultaneously able to interact with the specific client and the central chaperone itself. Recruitment of ATP and co-chaperone followed by client protein forms a functional chaperone. After the completion of the chaperoning process, properly folded client protein and co-chaperone leave HSP90 in an ADP-bound partially open conformation and finally, ADP is released from HSP90 which acquires an open conformation for the next cycle. Plays a critical role in mitochondrial import, delivers preproteins to the mitochondrial import receptor TOMM70. Apart from its chaperone activity, it also plays a role in the regulation of the transcription machinery. HSP90 and its co-chaperones modulate transcription at least at three different levels. In the first place, they alter the steady-state levels of certain transcription factors in response to various physiological cues. Second, they modulate the activity of certain epigenetic modifiers, such as histone deacetylases or DNA methyl transferases, and thereby respond to the change in the environment. Third, they participate in the eviction of histones from the promoter region of certain genes and thereby turn on gene expression. Binds bacterial lipopolysaccharide (LPS) and mediates LPS-induced inflammatory response, including TNF secretion by monocytes. Antagonizes STUB1-mediated inhibition of TGF-beta signaling via inhibition of STUB1-mediated SMAD3 ubiquitination and degradation. Mediates the association of TOMM70 with IRF3 or TBK1 in mitochondrial outer membrane which promotes host antiviral response., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0030911 TPR domain binding;GO:0005524 ATP binding;GO:0051082 unfolded protein binding;GO:0016887 ATP hydrolysis activity;GO:0030235 nitric-oxide synthase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005886 plasma membrane;GO:0042470 melanosome", "go_biological_process": "GO:0009409 response to cold;GO:0045429 positive regulation of nitric oxide biosynthetic process;GO:0032880 regulation of protein localization;GO:0002230 positive regulation of defense response to virus by host;GO:0046677 response to antibiotic", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "P46633-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P46636-1", "uniprot_id": [ { "id": "5HT1B_CRIGR", "url": "https://www.uniprot.org/uniprot/P46636", "type": "external" } ], "mass": 42896.0, "length": 386, "protein_name": "5-hydroxytryptamine receptor 1B", "gene_name": "HTR1B", "organism": "Hamster", "refseq_name": "5-hydroxytryptamine receptor 1B", "refseq_ac": [ { "id": "NP_001233683", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233683", "type": "external" } ], "gene_names_uniprotkb": "HTR1B", "gene_names_refseq": "5-HT-1B; 5-ht1b; Htr1b", "protein_names_uniprotkb": "5-hydroxytryptamine receptor 1B; 5-HT-1B; 5-HT1B; Serotonin receptor 1B", "protein_names_refseq": "5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled; 5-hydroxytryptamine receptor 1B; Serotonin receptor 1B", "tax_id": 10029, "disease": "", "pathway": " (cge:100689321)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: X86458.1 [ECO:0000332] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X86458.1., [RefSeq]; G protein-coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances, such as lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. HTR1B is coupled to G(i)/G(o) G alpha proteins and mediates inhibitory neurotransmission by inhibiting adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004993 G protein-coupled serotonin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0098793 presynapse;GO:0099154 serotonergic synapse", "go_biological_process": "GO:0043410 positive regulation of MAPK cascade;GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0007268 chemical synaptic transmission;GO:0071466 cellular response to xenobiotic stimulus;GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "P46636-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P48670-1", "uniprot_id": [ { "id": "VIME_CRIGR", "url": "https://www.uniprot.org/uniprot/P48670", "type": "external" } ], "mass": 51849.0, "length": 448, "protein_name": "Vimentin", "gene_name": "VIM", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "VIM", "gene_names_refseq": "", "protein_names_uniprotkb": "Vimentin", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "6688458", "class_list": "", "function": "Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2., [UniProtKB, UniProtKB]; Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. Plays a role in cell directional movement, orientation, cell sheet organization and Golgi complex polarization at the cell migration front (By similarity). Protects SCRIB from proteasomal degradation and facilitates its localization to intermediate filaments in a cell contact-mediated manner (By similarity). May promote axon outgrowth and motor fiber repair via DSP-mediated recruitment to outgrowth tips (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 32, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005200 structural constituent of cytoskeleton", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0030424 axon;GO:0005882 intermediate filament;GO:0016363 nuclear matrix", "go_biological_process": "GO:0071222 cellular response to lipopolysaccharide;GO:0045109 intermediate filament organization;GO:0071225 cellular response to muramyl dipeptide;GO:0010634 positive regulation of epithelial cell migration", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P48670-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P48761-1", "uniprot_id": [ { "id": "SL9A1_CRIGR", "url": "https://www.uniprot.org/uniprot/P48761", "type": "external" } ], "mass": 92004.0, "length": 822, "protein_name": "Sodium/hydrogen exchanger 1", "gene_name": "SLC9A1", "organism": "Hamster", "refseq_name": "sodium/hydrogen exchanger 1", "refseq_ac": [ { "id": "NP_001233682", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233682", "type": "external" } ], "gene_names_uniprotkb": "SLC9A1; NHE1", "gene_names_refseq": "NHE-1; NHE1; Slc9a1", "protein_names_uniprotkb": "Sodium/hydrogen exchanger 1; NHE-1; Na(+)/H(+) exchanger 1; Solute carrier family 9 member 1", "protein_names_refseq": "Na(+)/H(+) exchanger 1; Solute carrier family 9 member 1; sodium/hydrogen exchanger 1; solute carrier family 9 (sodium/hydrogen exchanger), member 1; solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100689320)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "8383540", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: X68970.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN04275174, SAMN04275175 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X68970.1., [RefSeq]; Electroneutral Na(+) /H(+) antiporter that extrudes Na(+) in exchange for external protons driven by the inward sodium ion chemical gradient, protecting cells from acidification that occurs from metabolism (By similarity). Exchanges intracellular H(+) ions for extracellular Na(+) in 1:1 stoichiometry (By similarity). Plays a key role in maintening intracellular pH neutral and cell volume, and thus is important for cell growth, proliferation, migration and survival. In addition, can transport lithium Li(+) and also functions as a Na(+)/Li(+) antiporter. SLC9A1 also functions in membrane anchoring and organization of scaffolding complexes that coordinate signaling inputs (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 16, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015385 sodium:proton antiporter activity;GO:0015386 potassium:proton antiporter activity;GO:0005516 calmodulin binding;GO:0048306 calcium-dependent protein binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0051259 protein complex oligomerization;GO:0010447 response to acidic pH;GO:0036376 sodium ion export across plasma membrane;GO:0051453 regulation of intracellular pH;GO:0071468 cellular response to acidic pH", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P48761-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P49130-1", "uniprot_id": [ { "id": "LAMP2_CRIGR", "url": "https://www.uniprot.org/uniprot/P49130", "type": "external" } ], "mass": 45028.0, "length": 410, "protein_name": "Lysosome-associated membrane glycoprotein 2", "gene_name": "LAMP2", "organism": "Hamster", "refseq_name": "lysosome-associated membrane glycoprotein 2 precursor", "refseq_ac": [ { "id": "NP_001233678", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233678", "type": "external" } ], "gene_names_uniprotkb": "LAMP2; LGPB", "gene_names_refseq": "LAMP-2; LGP-B; Lamp2; Lgpb", "protein_names_uniprotkb": "Lysosome-associated membrane glycoprotein 2; CD107 antigen-like family member B; LAMP-2; LGP-B; Lysosomal membrane glycoprotein B; Lysosome-associated membrane protein 2", "protein_names_refseq": "CD107 antigen-like family member B; Lysosome-associated membrane glycoprotein 2; Lysosome-associated membrane protein 2; lysosomal membrane glycoprotein B; lysosome-associated membrane glycoprotein 2 precursor", "tax_id": 10029, "disease": "", "pathway": " (cge:100689316)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "8867788", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: L19357.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN04275174, SAMN04275175 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from L19357.1., [RefSeq]; Lysosomal membrane glycoprotein which plays an important role in lysosome biogenesis, lysosomal pH regulation and autophagy. Acts as an important regulator of lysosomal lumen pH regulation by acting as a direct inhibitor of the proton channel TMEM175, facilitating lysosomal acidification for optimal hydrolase activity. Plays an important role in chaperone-mediated autophagy, a process that mediates lysosomal degradation of proteins in response to various stresses and as part of the normal turnover of proteins with a long biological half-live. Functions by binding target proteins, such as GAPDH, GPX4, NLRP3 and MLLT11, and targeting them for lysosomal degradation. In the chaperone-mediated autophagy, acts downstream of chaperones, such as HSPA8/HSC70, which recognize and bind substrate proteins and mediate their recruitment to lysosomes, where target proteins bind LAMP2. Plays a role in lysosomal protein degradation in response to starvation. Required for the fusion of autophagosomes with lysosomes during autophagy. Cells that lack LAMP2 express normal levels of VAMP8, but fail to accumulate STX17 on autophagosomes, which is the most likely explanation for the lack of fusion between autophagosomes and lysosomes. Required for normal degradation of the contents of autophagosomes. Required for efficient MHC class II-mediated presentation of exogenous antigens via its function in lysosomal protein degradation; antigenic peptides generated by proteases in the endosomal/lysosomal compartment are captured by nascent MHC II subunits. Is not required for efficient MHC class II-mediated presentation of endogenous antigens (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 17, "predicted_n_glycosites": 17, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 17, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008200 ion channel inhibitor activity", "go_cellular_component": "GO:0000421 autophagosome membrane;GO:0005886 plasma membrane;GO:0005764 lysosome;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane", "go_biological_process": "GO:0097352 autophagosome maturation;GO:0061684 chaperone-mediated autophagy;GO:0006605 protein targeting;GO:0050821 protein stabilization;GO:0009267 cellular response to starvation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P49130-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P49584-1", "uniprot_id": [ { "id": "PCY1A_CRIGR", "url": "https://www.uniprot.org/uniprot/P49584", "type": "external" } ], "mass": 41717.0, "length": 367, "protein_name": "Choline-phosphate cytidylyltransferase A", "gene_name": "PCYT1A", "organism": "Hamster", "refseq_name": "choline-phosphate cytidylyltransferase A", "refseq_ac": [ { "id": "NP_001233666", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233666", "type": "external" } ], "gene_names_uniprotkb": "PCYT1A; CTPCT; PCYT1", "gene_names_refseq": "CCT-alpha; CTPCT; PCYT1; Pcyt1a", "protein_names_uniprotkb": "Choline-phosphate cytidylyltransferase A; 2.7.7.15; CCT A; CCT-alpha; CT A; CTP:phosphocholine cytidylyltransferase A; Phosphorylcholine transferase A", "protein_names_refseq": "CCT A; CT A; CTP:phosphocholine cytidylyltransferase A; Phosphorylcholine transferase A; choline-phosphate cytidylyltransferase A", "tax_id": 10029, "disease": "", "pathway": " (cge:100689303)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "8185307", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: L13244.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN04275174, SAMN04275175 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from L13244.1., [RefSeq]; Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 19, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.15", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.15", "type": "external" } ], "go_molecular_function": "GO:0004105 choline-phosphate cytidylyltransferase activity;GO:0031210 phosphatidylcholine binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006657 CDP-choline pathway;GO:0006656 phosphatidylcholine biosynthetic process;GO:0045190 isotype switching;GO:0042100 B cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P49584-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P68361-1", "uniprot_id": [ { "id": "TBA1B_CRIGR", "url": "https://www.uniprot.org/uniprot/P68361", "type": "external" } ], "mass": 50152.0, "length": 451, "protein_name": "Tubulin alpha-1B chain", "gene_name": "TUBA1B", "organism": "Hamster", "refseq_name": "tubulin alpha-1B chain", "refseq_ac": [ { "id": "NP_001230908", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230908", "type": "external" } ], "gene_names_uniprotkb": "TUBA1B; TUBA1", "gene_names_refseq": "Calpha1; Tuba1b; Tuba1", "protein_names_uniprotkb": "Tubulin alpha-1B chain; 3.6.5.-; Alpha-tubulin 1; Alpha-tubulin I; Tubulin alpha-1 chain", "protein_names_refseq": "Alpha-tubulin 1; Tubulin alpha-1 chain; Tubulin alpha-1A chain; alpha tubulin; alpha-tubulin I; tubulin alpha-1B chain", "tax_id": 10029, "disease": "", "pathway": " (cge:100682528)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "3773896", "class_list": "", "function": "Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P04687;P05209", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005200 structural constituent of cytoskeleton;GO:0005525 GTP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005874 microtubule;GO:0015630 microtubule cytoskeleton", "go_biological_process": "GO:0000226 microtubule cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P68361-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P68362-1", "uniprot_id": [ { "id": "TBA1A_CRIGR", "url": "https://www.uniprot.org/uniprot/P68362", "type": "external" } ], "mass": 50136.0, "length": 451, "protein_name": "Tubulin alpha-1A chain", "gene_name": "TUBA1A", "organism": "Hamster", "refseq_name": "tubulin alpha-1A chain", "refseq_ac": [ { "id": "NP_001230907", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230907", "type": "external" } ], "gene_names_uniprotkb": "TUBA1A; TUBA2", "gene_names_refseq": "Tuba1a; Tuba2", "protein_names_uniprotkb": "Tubulin alpha-1A chain; 3.6.5.-; Alpha-tubulin 2; Alpha-tubulin II; Tubulin alpha-2 chain", "protein_names_refseq": "Alpha-tubulin 2; Tubulin alpha-2 chain; alpha-tubulin II; tubulin alpha-1A chain", "tax_id": 10029, "disease": "", "pathway": " (cge:100682527)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "3773896", "class_list": "", "function": "Tubulin is the major constituent of microtubules, protein filaments consisting of alpha- and beta-tubulin heterodimers (By similarity). Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms (By similarity). Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P02551;P05210;P05212", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" } ], "go_molecular_function": "GO:0005200 structural constituent of cytoskeleton;GO:0005525 GTP binding;GO:0016787 hydrolase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005874 microtubule", "go_biological_process": "GO:0007017 microtubule-based process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P68362-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q07050-1", "uniprot_id": [ { "id": "TOP1_CRIGR", "url": "https://www.uniprot.org/uniprot/Q07050", "type": "external" } ], "mass": 90868.0, "length": 767, "protein_name": "DNA topoisomerase 1", "gene_name": "TOP1", "organism": "Hamster", "refseq_name": "DNA topoisomerase 1", "refseq_ac": [ { "id": "NP_001230963", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230963", "type": "external" } ], "gene_names_uniprotkb": "TOP1; TOP-1", "gene_names_refseq": "TOP-1; Top1", "protein_names_uniprotkb": "DNA topoisomerase 1; 5.6.2.1; DNA topoisomerase I", "protein_names_refseq": "DNA topoisomerase 1; topoisomerase (DNA) I", "tax_id": 10029, "disease": "", "pathway": " (cge:100689046)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "8244980", "class_list": "", "function": "Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then rotates around the intact phosphodiester bond on the opposing strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells. Involved in the circadian transcription of the core circadian clock component BMAL1 by altering the chromatin structure around the ROR response elements (ROREs) on the BMAL1 promoter., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003917 DNA topoisomerase type I (single strand cut, ATP-independent) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005694 chromosome", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0007059 chromosome segregation;GO:0006260 DNA replication;GO:0032922 circadian regulation of gene expression;GO:0006265 DNA topological change", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q07050-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q60452-1", "uniprot_id": [ { "id": "ERCC2_CRIGR", "url": "https://www.uniprot.org/uniprot/Q60452", "type": "external" } ], "mass": 86752.0, "length": 760, "protein_name": "General transcription and DNA repair factor IIH helicase subunit XPD", "gene_name": "ERCC2", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ERCC2; XPD", "gene_names_refseq": "", "protein_names_uniprotkb": "General transcription and DNA repair factor IIH helicase subunit XPD; 5.6.2.3; CXPD; DNA 5'-3' helicase XPD; DNA excision repair protein ERCC-2; DNA repair protein complementing XP-D cells; TFIIH subunit XPD; Xeroderma pigmentosum group D-complementing protein", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "11182546;7851887;8052270", "class_list": "", "function": "ATP-dependent 5'-3' DNA helicase (PubMed:11182546). Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA (PubMed:11182546). When complexed to CDK-activating kinase (CAK), involved in transcription by RNA polymerase II (PubMed:11182546). In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. The ATP-dependent helicase activity of XPD/ERCC2 is required for DNA opening. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription. XPD/ERCC2 acts by forming a bridge between CAK and the core-TFIIH complex. Involved in the regulation of vitamin-D receptor activity. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation. Might have a role in aging process and could play a causative role in the generation of skin cancers., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 8, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0003684 damaged DNA binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005819 spindle;GO:0071817 MMXD complex;GO:0005675 transcription factor TFIIH holo complex", "go_biological_process": "GO:0006979 response to oxidative stress;GO:0007059 chromosome segregation;GO:0006915 apoptotic process;GO:0006366 transcription by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q60452-1", "record_type": "protein", "filter_code": "0000000.0100100.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q60457-1", "uniprot_id": [ { "id": "SOAT1_CRIGR", "url": "https://www.uniprot.org/uniprot/Q60457", "type": "external" } ], "mass": 64111.0, "length": 546, "protein_name": "Sterol O-acyltransferase 1", "gene_name": "SOAT1", "organism": "Hamster", "refseq_name": "sterol O-acyltransferase 1", "refseq_ac": [ { "id": "NP_001233679", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233679", "type": "external" } ], "gene_names_uniprotkb": "SOAT1; ACAT1; ACAT", "gene_names_refseq": "ACAT-1; ACAT1; Acat; Soat1", "protein_names_uniprotkb": "Sterol O-acyltransferase 1; 2.3.1.26; ACAT-1; Acyl-coenzyme A:cholesterol acyltransferase 1; Cholesterol acyltransferase 1", "protein_names_refseq": "Acyl-coenzyme A:cholesterol acyltransferase 1; Cholesterol acyltransferase 1; sterol O-acyltransferase 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100689317)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "8662991", "class_list": "", "function": "Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol. Plays a role in lipoprotein assembly and dietary cholesterol absorption. Preferentially utilizes oleoyl-CoA ((9Z)-octadecenoyl-CoA) as a substrate: shows a higher activity towards an acyl-CoA substrate with a double bond at the delta-9 position (9Z) than towards saturated acyl-CoA or an unsaturated acyl-CoA with a double bond at the delta-7 (7Z) or delta-11 (11Z) positions., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.26", "type": "external" } ], "go_molecular_function": "GO:0015485 cholesterol binding;GO:0000062 fatty-acyl-CoA binding;GO:0004772 sterol O-acyltransferase activity;GO:0034736 cholesterol O-acyltransferase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0008203 cholesterol metabolic process;GO:0033344 cholesterol efflux;GO:0042632 cholesterol homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q60457-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FUN8-1", "uniprot_id": [ { "id": "A0A9J7FUN8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FUN8", "type": "external" } ], "mass": 108759.0, "length": 999, "protein_name": "E3 ubiquitin-protein ligase Arkadia", "gene_name": "Rnf111", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase Arkadia isoform X1", "refseq_ac": [ { "id": "XP_007646744", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646744", "type": "external" } ], "gene_names_uniprotkb": "Rnf111", "gene_names_refseq": "Rnf111", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase Arkadia; 2.3.2.27; RING finger protein 111; RING-type E3 ubiquitin transferase Arkadia", "protein_names_refseq": "E3 ubiquitin-protein ligase Arkadia isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100773181)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613582.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0032184 SUMO polymer binding", "go_cellular_component": "GO:0005829 cytosol;GO:0016605 PML body;GO:0032991 protein-containing complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0006281 DNA repair", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FUN8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FCG5-1", "uniprot_id": [ { "id": "A0A9J7FCG5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FCG5", "type": "external" } ], "mass": 105599.0, "length": 950, "protein_name": "phosphatidate phosphatase", "gene_name": "Lpin2", "organism": "Hamster", "refseq_name": "phosphatidate phosphatase LPIN2 isoform X3", "refseq_ac": [ { "id": "XP_027253629", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253629", "type": "external" } ], "gene_names_uniprotkb": "Lpin2", "gene_names_refseq": "Lpin2", "protein_names_uniprotkb": "phosphatidate phosphatase; 3.1.3.4", "protein_names_refseq": "phosphatidate phosphatase LPIN2 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100769904)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.4", "type": "external" }, { "id": "3.1.3.106", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.106", "type": "external" }, { "id": "3.6.1.75", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.75", "type": "external" } ], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0008195 phosphatidate phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0009062 fatty acid catabolic process;GO:0032869 cellular response to insulin stimulus;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0019432 triglyceride biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FCG5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FIM8-1", "uniprot_id": [ { "id": "A0A9J7FIM8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FIM8", "type": "external" } ], "mass": 88920.0, "length": 785, "protein_name": "Protein spire homolog 1 isoform X2", "gene_name": "Spire1", "organism": "Hamster", "refseq_name": "protein spire homolog 1 isoform X2", "refseq_ac": [ { "id": "XP_027258496", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258496", "type": "external" } ], "gene_names_uniprotkb": "Spire1", "gene_names_refseq": "Spire1", "protein_names_uniprotkb": "Protein spire homolog 1 isoform X2", "protein_names_refseq": "protein spire homolog 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100760597)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0008017 microtubule binding", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0005938 cell cortex", "go_biological_process": "GO:0015031 protein transport;GO:0030041 actin filament polymerization;GO:0051639 actin filament network formation;GO:0045010 actin nucleation;GO:0048193 Golgi vesicle transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FIM8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FRM1-1", "uniprot_id": [ { "id": "A0A9J7FRM1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FRM1", "type": "external" } ], "mass": 52715.0, "length": 463, "protein_name": "Ethanolamine kinase", "gene_name": "Chka", "organism": "Hamster", "refseq_name": "choline kinase alpha isoform X6", "refseq_ac": [ { "id": "XP_027264561", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264561", "type": "external" } ], "gene_names_uniprotkb": "Chka", "gene_names_refseq": "Chka", "protein_names_uniprotkb": "Ethanolamine kinase; 2.7.1.32; 2.7.1.82", "protein_names_refseq": "choline kinase alpha isoform X6", "tax_id": 10029, "disease": "", "pathway": " (cge:100767436)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.32", "type": "external" }, { "id": "2.7.1.82", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.82", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0042803 protein homodimerization activity;GO:0004103 choline kinase activity;GO:0004305 ethanolamine kinase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005737 cytoplasm", "go_biological_process": "GO:0006646 phosphatidylethanolamine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FRM1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FAH1-1", "uniprot_id": [ { "id": "A0A9J7FAH1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FAH1", "type": "external" } ], "mass": 185619.0, "length": 1664, "protein_name": "Kinesin-like protein KIF21A", "gene_name": "Kif21a", "organism": "Hamster", "refseq_name": "kinesin-like protein KIF21A isoform X4", "refseq_ac": [ { "id": "XP_027252127", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027252127", "type": "external" } ], "gene_names_uniprotkb": "Kif21a", "gene_names_refseq": "Kif21a", "protein_names_uniprotkb": "Kinesin-like protein KIF21A", "protein_names_refseq": "kinesin-like protein KIF21A isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100766958)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Processive microtubule plus-end directed motor protein involved in neuronal axon guidance. Is recruited by KANK1 to cortical microtubule stabilizing complexes (CMSCs) at focal adhesions (FAs) rims where it promotes microtubule capture and stability. Controls microtubule polymerization rate at axonal growth cones and suppresses microtubule growth without inducing microtubule disassembly once it reaches the cell cortex., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0003777 microtubule motor activity", "go_cellular_component": "GO:0005874 microtubule;GO:0030425 dendrite;GO:0030426 growth cone;GO:0005875 microtubule associated complex;GO:0005938 cell cortex", "go_biological_process": "GO:0007018 microtubule-based movement;GO:0007052 mitotic spindle organization;GO:0051231 spindle elongation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FAH1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FNJ4-1", "uniprot_id": [ { "id": "A0A9J7FNJ4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FNJ4", "type": "external" } ], "mass": 104903.0, "length": 938, "protein_name": "Kinesin-like protein", "gene_name": "Kifc3", "organism": "Hamster", "refseq_name": "kinesin-like protein KIFC3 isoform X3", "refseq_ac": [ { "id": "XP_027261489", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261489", "type": "external" } ], "gene_names_uniprotkb": "Kifc3", "gene_names_refseq": "Kifc3", "protein_names_uniprotkb": "Kinesin-like protein", "protein_names_refseq": "kinesin-like protein KIFC3 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100763525)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Minus-end microtubule-dependent motor protein. Involved in apically targeted transport. Required for zonula adherens maintenance., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0003777 microtubule motor activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005813 centrosome;GO:0005874 microtubule;GO:0005871 kinesin complex;GO:0030659 cytoplasmic vesicle membrane", "go_biological_process": "GO:0007018 microtubule-based movement;GO:0045218 zonula adherens maintenance;GO:0090136 epithelial cell-cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FNJ4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FEY2-1", "uniprot_id": [ { "id": "A0A9J7FEY2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FEY2", "type": "external" } ], "mass": 42925.0, "length": 374, "protein_name": "Casein kinase I isoform alpha", "gene_name": "Csnk1a1", "organism": "Hamster", "refseq_name": "casein kinase I isoform X1", "refseq_ac": [ { "id": "XP_016834282", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016834282", "type": "external" } ], "gene_names_uniprotkb": "Csnk1a1", "gene_names_refseq": "Csnk1a1", "protein_names_uniprotkb": "Casein kinase I isoform alpha; 2.7.11.1; CK1", "protein_names_refseq": "casein kinase I isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100758298)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 642 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614565.1) and transcript sequence (IACG01043080.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis. May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration. Acts as a positive regulator of mTORC1 and mTORC2 signaling in response to nutrients by mediating phosphorylation of DEPTOR inhibitor. Acts as an inhibitor of NLRP3 inflammasome assembly by mediating phosphorylation of NLRP3., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016607 nuclear speck;GO:0000776 kinetochore;GO:0005813 centrosome;GO:0005829 cytosol", "go_biological_process": "GO:0016055 Wnt signaling pathway;GO:1904263 positive regulation of TORC1 signaling;GO:0031670 cellular response to nutrient;GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0035025 positive regulation of Rho protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FEY2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FIT3-1", "uniprot_id": [ { "id": "A0A9J7FIT3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FIT3", "type": "external" } ], "mass": 113507.0, "length": 1029, "protein_name": "Solute carrier family 12 member 3", "gene_name": "Slc12a3", "organism": "Hamster", "refseq_name": "solute carrier family 12 member 3 isoform X1", "refseq_ac": [ { "id": "XP_007642390", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642390", "type": "external" } ], "gene_names_uniprotkb": "Slc12a3", "gene_names_refseq": "Slc12a3", "protein_names_uniprotkb": "Solute carrier family 12 member 3; Na-Cl symporter; Thiazide-sensitive sodium-chloride cotransporter", "protein_names_refseq": "solute carrier family 12 member 3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100758081)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613984.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Electroneutral sodium and chloride ion cotransporter, which acts as a key mediator of sodium and chloride reabsorption in kidney distal convoluted tubules. Also acts as a receptor for the pro-inflammatory cytokine IL18, thereby contributing to IL18-induced cytokine production, including IFNG, IL6, IL18 and CCL2. May act either independently of IL18R1, or in a complex with IL18R1., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008511 sodium:potassium:chloride symporter activity", "go_cellular_component": "GO:0005829 cytosol;GO:0070062 extracellular exosome;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0006884 cell volume homeostasis;GO:0055075 potassium ion homeostasis;GO:0055078 sodium ion homeostasis;GO:1990573 potassium ion import across plasma membrane;GO:0055064 chloride ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FIT3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FEP0-1", "uniprot_id": [ { "id": "A0A9J7FEP0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FEP0", "type": "external" } ], "mass": 90062.0, "length": 792, "protein_name": "Phosphodiesterase", "gene_name": "Pde10a", "organism": "Hamster", "refseq_name": "cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X4", "refseq_ac": [ { "id": "XP_027256915", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256915", "type": "external" } ], "gene_names_uniprotkb": "Pde10a", "gene_names_refseq": "Pde10a", "protein_names_uniprotkb": "Phosphodiesterase; 3.1.4.-", "protein_names_refseq": "cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100751551)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.4.35", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.35", "type": "external" }, { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" }, { "id": "3.1.4.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.53", "type": "external" }, { "id": "3.1.4.17", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.17", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0030552 cAMP binding;GO:0030553 cGMP binding;GO:0004118 3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activity;GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005829 cytosol", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FEP0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FAJ1-1", "uniprot_id": [ { "id": "A0A9J7FAJ1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FAJ1", "type": "external" } ], "mass": 43127.0, "length": 382, "protein_name": "CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase", "gene_name": "St3gal3", "organism": "Hamster", "refseq_name": "CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X2", "refseq_ac": [ { "id": "XP_016831201", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831201", "type": "external" } ], "gene_names_uniprotkb": "St3gal3", "gene_names_refseq": "St3gal3", "protein_names_uniprotkb": "CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase; 2.4.3.6; Beta-galactoside alpha-2,3-sialyltransferase 3; Gal beta-1,3(4) GlcNAc alpha-2,3 sialyltransferase; N-acetyllactosaminide alpha-2,3-sialyltransferase; ST3Gal III; ST3N; Sialyltransferase 6", "protein_names_refseq": "CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X2", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613906.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the formation of the NeuAc-alpha-2,3-Gal-beta-1,4-GlcNAc-, NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- and NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. The highest activity is toward Gal-beta-1,3-GlcNAc and the lowest toward Gal-beta-1,3-GalNAc., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.3.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.3.6", "type": "external" } ], "go_molecular_function": "GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity;GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity", "go_cellular_component": "GO:0032580 Golgi cisterna membrane", "go_biological_process": "GO:0009101 glycoprotein biosynthetic process;GO:0001574 ganglioside biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FAJ1-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FUU9-1", "uniprot_id": [ { "id": "A0A9J7FUU9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FUU9", "type": "external" } ], "mass": 143767.0, "length": 1272, "protein_name": "Polyamine-transporting ATPase 13A3", "gene_name": "Atp13a3", "organism": "Hamster", "refseq_name": "probable cation-transporting ATPase 13A3 isoform X4", "refseq_ac": [ { "id": "XP_027268700", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268700", "type": "external" } ], "gene_names_uniprotkb": "Atp13a3", "gene_names_refseq": "Atp13a3", "protein_names_uniprotkb": "Polyamine-transporting ATPase 13A3; 7.6.2.16; Putrescine transporting ATPase", "protein_names_refseq": "probable cation-transporting ATPase 13A3 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100769908)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; ATP-driven pump involved in endocytosis-dependent polyamine transport. Uses ATP as an energy source to transfer polyamine precursor putrescine from the endosomal compartment to the cytosol., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "7.6.2.16", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.16", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity;GO:0015662 P-type ion transporter activity", "go_cellular_component": "GO:0031902 late endosome membrane;GO:0031901 early endosome membrane;GO:0055038 recycling endosome membrane", "go_biological_process": "GO:0006874 intracellular calcium ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FUU9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FV91-1", "uniprot_id": [ { "id": "A0A9J7FV91_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FV91", "type": "external" } ], "mass": 68570.0, "length": 620, "protein_name": "Insulin-like growth factor 2 mRNA-binding protein 2", "gene_name": "Igf2bp2", "organism": "Hamster", "refseq_name": "insulin-like growth factor 2 mRNA-binding protein 2 isoform X1", "refseq_ac": [ { "id": "XP_003504270", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504270", "type": "external" } ], "gene_names_uniprotkb": "Igf2bp2", "gene_names_refseq": "Igf2bp2", "protein_names_uniprotkb": "Insulin-like growth factor 2 mRNA-binding protein 2; IGF-II mRNA-binding protein 2; VICKZ family member 2", "protein_names_refseq": "insulin-like growth factor 2 mRNA-binding protein 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100755568)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 273 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614046.1) and transcript sequence (IACG01032918.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003504270.1. COMPLETENESS: full length., [RefSeq]; RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Preferentially binds to N6-methyladenosine (m6A)-containing mRNAs and increases their stability. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific. Binds to beta-actin/ACTB and MYC transcripts. Increases MYC mRNA stability by binding to the coding region instability determinant (CRD) and binding is enhanced by m6A-modification of the CRD., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003730 mRNA 3'-UTR binding;GO:0045182 translation regulator activity;GO:0048027 mRNA 5'-UTR binding;GO:1990247 N6-methyladenosine-containing RNA reader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0000932 P-body;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0070934 CRD-mediated mRNA stabilization;GO:0017148 negative regulation of translation;GO:0051028 mRNA transport;GO:0006417 regulation of translation;GO:0010605 negative regulation of macromolecule metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FV91-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FJK2-1", "uniprot_id": [ { "id": "A0A9J7FJK2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FJK2", "type": "external" } ], "mass": 185632.0, "length": 1653, "protein_name": "RNA uridylyltransferase", "gene_name": "Tut4", "organism": "Hamster", "refseq_name": "terminal uridylyltransferase 4 isoform X1", "refseq_ac": [ { "id": "XP_027258220", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258220", "type": "external" } ], "gene_names_uniprotkb": "Tut4", "gene_names_refseq": "Tut4", "protein_names_uniprotkb": "RNA uridylyltransferase; 2.7.7.52", "protein_names_refseq": "terminal uridylyltransferase 4 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100755521)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.52", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.52", "type": "external" }, { "id": "2.7.7.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.19", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003676 nucleic acid binding;GO:0050265 RNA uridylyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0001556 oocyte maturation;GO:0010586 miRNA metabolic process;GO:0031123 RNA 3'-end processing;GO:1990074 polyuridylation-dependent mRNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FJK2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FXB4-1", "uniprot_id": [ { "id": "A0A9J7FXB4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FXB4", "type": "external" } ], "mass": 150687.0, "length": 1362, "protein_name": "Ubiquitin carboxyl-terminal hydrolase 19", "gene_name": "Usp19", "organism": "Hamster", "refseq_name": "ubiquitin carboxyl-terminal hydrolase 19 isoform X1", "refseq_ac": [ { "id": "XP_027270371", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270371", "type": "external" } ], "gene_names_uniprotkb": "Usp19", "gene_names_refseq": "Usp19", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase 19; 3.4.19.12; Deubiquitinating enzyme 19; Ubiquitin thioesterase 19; Ubiquitin-specific-processing protease 19", "protein_names_refseq": "ubiquitin carboxyl-terminal hydrolase 19 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100762852)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0051879 Hsp90 protein binding;GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:1904292 regulation of ERAD pathway;GO:0016579 protein deubiquitination;GO:0050821 protein stabilization;GO:0036503 ERAD pathway;GO:1900037 regulation of cellular response to hypoxia", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FXB4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FGU6-1", "uniprot_id": [ { "id": "A0A9J7FGU6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FGU6", "type": "external" } ], "mass": 52771.0, "length": 466, "protein_name": "NAD kinase 2, mitochondrial", "gene_name": "Nadk2", "organism": "Hamster", "refseq_name": "NAD kinase 2, mitochondrial isoform X2", "refseq_ac": [ { "id": "XP_027257106", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257106", "type": "external" } ], "gene_names_uniprotkb": "Nadk2", "gene_names_refseq": "Nadk2", "protein_names_uniprotkb": "NAD kinase 2, mitochondrial; 2.7.1.23; NAD kinase domain-containing protein 1, mitochondrial", "protein_names_refseq": "NAD kinase 2, mitochondrial isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100773611)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.23", "type": "external" } ], "go_molecular_function": "GO:0003951 NAD+ kinase activity;GO:0005524 ATP binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006741 NADP+ biosynthetic process;GO:0019674 NAD+ metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FGU6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FCF4-1", "uniprot_id": [ { "id": "A0A9J7FCF4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FCF4", "type": "external" } ], "mass": 134742.0, "length": 1220, "protein_name": "Partitioning defective 3 homolog B", "gene_name": "LOC100770975", "organism": "Hamster", "refseq_name": "partitioning defective 3 homolog B isoform X2", "refseq_ac": [ { "id": "XP_027252832", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027252832", "type": "external" } ], "gene_names_uniprotkb": "LOC100770975", "gene_names_refseq": "LOC100770975", "protein_names_uniprotkb": "Partitioning defective 3 homolog B; PAR3-beta; Partitioning defective 3-like protein", "protein_names_refseq": "partitioning defective 3 homolog B isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100770975)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Putative adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0035091 phosphatidylinositol binding", "go_cellular_component": "GO:0005912 adherens junction;GO:0005923 bicellular tight junction;GO:0005938 cell cortex;GO:0012505 endomembrane system;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0007155 cell adhesion;GO:0051301 cell division;GO:0008104 intracellular protein localization;GO:0000226 microtubule cytoskeleton organization;GO:0030010 establishment of cell polarity", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FCF4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FMS3-1", "uniprot_id": [ { "id": "A0A9J7FMS3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FMS3", "type": "external" } ], "mass": 78576.0, "length": 673, "protein_name": "Zinc finger MYND domain-containing protein 11", "gene_name": "Zmynd11", "organism": "Hamster", "refseq_name": "zinc finger MYND domain-containing protein 11 isoform X1", "refseq_ac": [ { "id": "XP_016834684", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016834684", "type": "external" } ], "gene_names_uniprotkb": "Zmynd11", "gene_names_refseq": "Zmynd11", "protein_names_uniprotkb": "Zinc finger MYND domain-containing protein 11", "protein_names_refseq": "zinc finger MYND domain-containing protein 11 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100753657)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 153 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614706.1) and transcript sequence (IACG01101684.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Binds non-specifically to dsDNA. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0003714 transcription corepressor activity;GO:0140003 histone H3K36me3 reader activity;GO:0003690 double-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome;GO:0005654 nucleoplasm", "go_biological_process": "GO:0034243 regulation of transcription elongation by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0009966 regulation of signal transduction;GO:0051607 defense response to virus;GO:0043124 negative regulation of canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FMS3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FDH7-1", "uniprot_id": [ { "id": "A0A9J7FDH7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FDH7", "type": "external" } ], "mass": 88937.0, "length": 776, "protein_name": "Exocyst complex component 3", "gene_name": "Exoc3", "organism": "Hamster", "refseq_name": "exocyst complex component 3 isoform X2", "refseq_ac": [ { "id": "XP_027255968", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255968", "type": "external" } ], "gene_names_uniprotkb": "Exoc3", "gene_names_refseq": "Exoc3", "protein_names_uniprotkb": "Exocyst complex component 3; Exocyst complex component Sec6", "protein_names_refseq": "exocyst complex component 3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756215)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000149 SNARE binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0016020 membrane;GO:0030426 growth cone;GO:0048471 perinuclear region of cytoplasm;GO:0030496 midbody", "go_biological_process": "GO:0051601 exocyst localization;GO:0015031 protein transport;GO:0006887 exocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FDH7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F972-1", "uniprot_id": [ { "id": "A0A9J7F972_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F972", "type": "external" } ], "mass": 106695.0, "length": 982, "protein_name": "E3 ubiquitin-protein ligase MIB2", "gene_name": "Mib2", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase MIB2 isoform X1", "refseq_ac": [ { "id": "XP_007648668", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007648668", "type": "external" } ], "gene_names_uniprotkb": "Mib2", "gene_names_refseq": "Mib2", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase MIB2; 2.3.2.27; Mind bomb homolog 2; RING-type E3 ubiquitin transferase MIB2", "protein_names_refseq": "E3 ubiquitin-protein ligase MIB2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100773643)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614774.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005768 endosome;GO:0005737 cytoplasm", "go_biological_process": "GO:0007219 Notch signaling pathway;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F972-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F9W3-1", "uniprot_id": [ { "id": "A0A9J7F9W3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F9W3", "type": "external" } ], "mass": 227288.0, "length": 2041, "protein_name": "5'-3' DNA helicase ZGRF1", "gene_name": "Zgrf1", "organism": "Hamster", "refseq_name": "protein ZGRF1 isoform X2", "refseq_ac": [ { "id": "XP_027251470", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251470", "type": "external" } ], "gene_names_uniprotkb": "Zgrf1", "gene_names_refseq": "Zgrf1", "protein_names_uniprotkb": "5'-3' DNA helicase ZGRF1; 5.6.2.3; GRF-type zinc finger domain-containing protein 1", "protein_names_refseq": "protein ZGRF1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100755417)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0016787 hydrolase activity;GO:0043139 5'-3' DNA helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0035861 site of double-strand break", "go_biological_process": "GO:0006302 double-strand break repair", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F9W3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F927-1", "uniprot_id": [ { "id": "A0A9J7F927_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F927", "type": "external" } ], "mass": 104279.0, "length": 962, "protein_name": "Mitogen-activated protein kinase kinase kinase 12", "gene_name": "Map3k12", "organism": "Hamster", "refseq_name": "mitogen-activated protein kinase kinase kinase 12 isoform X5", "refseq_ac": [ { "id": "XP_027252505", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027252505", "type": "external" } ], "gene_names_uniprotkb": "Map3k12", "gene_names_refseq": "Map3k12", "protein_names_uniprotkb": "Mitogen-activated protein kinase kinase kinase 12; 2.7.11.25", "protein_names_refseq": "mitogen-activated protein kinase kinase kinase 12 isoform X5", "tax_id": 10029, "disease": "", "pathway": " (cge:100765738)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be an activator of the JNK/SAPK pathway., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0043539 protein serine/threonine kinase activator activity;GO:0004709 MAP kinase kinase kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "GO:0007254 JNK cascade", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F927-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FN44-1", "uniprot_id": [ { "id": "A0A9J7FN44_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FN44", "type": "external" } ], "mass": 27489.0, "length": 249, "protein_name": "Methylosome subunit pICln", "gene_name": "Clns1a", "organism": "Hamster", "refseq_name": "methylosome subunit pICln isoform X1", "refseq_ac": [ { "id": "XP_007649215", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649215", "type": "external" } ], "gene_names_uniprotkb": "Clns1a", "gene_names_refseq": "Clns1a", "protein_names_uniprotkb": "Methylosome subunit pICln; Chloride channel, nucleotide sensitive 1A; Chloride conductance regulatory protein ICln", "protein_names_refseq": "methylosome subunit pICln isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100768284)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614874.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in both the assembly of spliceosomal snRNPs and the methylation of Sm proteins. Chaperone that regulates the assembly of spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core). In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005681 spliceosomal complex;GO:0015630 microtubule cytoskeleton", "go_biological_process": "GO:0006884 cell volume homeostasis;GO:0006821 chloride transport;GO:0000387 spliceosomal snRNP assembly;GO:0045292 mRNA cis splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FN44-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FX31-1", "uniprot_id": [ { "id": "A0A9J7FX31_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FX31", "type": "external" } ], "mass": 73582.0, "length": 686, "protein_name": "Transcription initiation factor TFIID subunit 6", "gene_name": "Taf6", "organism": "Hamster", "refseq_name": "transcription initiation factor TFIID subunit 6 isoform X1", "refseq_ac": [ { "id": "XP_007649226", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649226", "type": "external" } ], "gene_names_uniprotkb": "Taf6", "gene_names_refseq": "Taf6", "protein_names_uniprotkb": "Transcription initiation factor TFIID subunit 6; Transcription initiation factor TFIID 70 kDa subunit; Transcription initiation factor TFIID 80 kDa subunit; p80", "protein_names_refseq": "transcription initiation factor TFIID subunit 6 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100775090)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614875.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. The TFIID complex structure can be divided into 3 modules TFIID-A, TFIID-B, and TFIID-C. TAF6 homodimer connects TFIID modules, forming a rigid core., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003713 transcription coactivator activity;GO:0046982 protein heterodimerization activity;GO:0017162 aryl hydrocarbon receptor binding;GO:0003743 translation initiation factor activity", "go_cellular_component": "GO:0033276 transcription factor TFTC complex;GO:0071339 MLL1 complex;GO:0005669 transcription factor TFIID complex;GO:0000124 SAGA complex;GO:0046695 SLIK (SAGA-like) complex", "go_biological_process": "GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0045786 negative regulation of cell cycle;GO:0042789 mRNA transcription by RNA polymerase II;GO:0051123 RNA polymerase II preinitiation complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FX31-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FTT2-1", "uniprot_id": [ { "id": "A0A9J7FTT2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FTT2", "type": "external" } ], "mass": 86249.0, "length": 769, "protein_name": "DNA replication licensing factor MCM5", "gene_name": "Mcm5", "organism": "Hamster", "refseq_name": "DNA replication licensing factor MCM5 isoform X1", "refseq_ac": [ { "id": "XP_007650656", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650656", "type": "external" } ], "gene_names_uniprotkb": "Mcm5", "gene_names_refseq": "Mcm5", "protein_names_uniprotkb": "DNA replication licensing factor MCM5; 3.6.4.12", "protein_names_refseq": "DNA replication licensing factor MCM5 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100756580)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615294.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007650656.1. COMPLETENESS: full length., [RefSeq]; Acts as a component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0003688 DNA replication origin binding;GO:0043138 3'-5' DNA helicase activity;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0042555 MCM complex;GO:0071162 CMG complex", "go_biological_process": "GO:0006270 DNA replication initiation;GO:0000727 double-strand break repair via break-induced replication", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FTT2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FVJ3-1", "uniprot_id": [ { "id": "A0A9J7FVJ3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FVJ3", "type": "external" } ], "mass": 199863.0, "length": 1790, "protein_name": "E3 ubiquitin-protein ligase RBBP6", "gene_name": "Rbbp6", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase RBBP6 isoform X1", "refseq_ac": [ { "id": "XP_007652786", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007652786", "type": "external" } ], "gene_names_uniprotkb": "Rbbp6", "gene_names_refseq": "Rbbp6", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RBBP6; 2.3.2.27; Proliferation potential-related protein; Protein P2P-R; RING-type E3 ubiquitin transferase RBBP6; Retinoblastoma-binding protein 6; p53-associated cellular protein of testis", "protein_names_refseq": "E3 ubiquitin-protein ligase RBBP6 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100773570)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616650.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003676 nucleic acid binding;GO:0061630 ubiquitin protein ligase activity;GO:0019901 protein kinase binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005813 centrosome;GO:0005694 chromosome;GO:0016607 nuclear speck;GO:0032991 protein-containing complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0006260 DNA replication;GO:0006974 DNA damage response;GO:0016567 protein ubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FVJ3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FNU5-1", "uniprot_id": [ { "id": "A0A9J7FNU5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FNU5", "type": "external" } ], "mass": 98492.0, "length": 865, "protein_name": "Inner centromere protein", "gene_name": "Incenp", "organism": "Hamster", "refseq_name": "inner centromere protein isoform X1", "refseq_ac": [ { "id": "XP_016819223", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016819223", "type": "external" } ], "gene_names_uniprotkb": "Incenp", "gene_names_refseq": "Incenp", "protein_names_uniprotkb": "Inner centromere protein", "protein_names_refseq": "inner centromere protein isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100770889)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003617091.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005874 microtubule;GO:0000776 kinetochore;GO:0030496 midbody;GO:0032133 chromosome passenger complex", "go_biological_process": "GO:0051310 metaphase chromosome alignment;GO:0000281 mitotic cytokinesis;GO:0051257 meiotic spindle midzone assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FNU5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FIG9-1", "uniprot_id": [ { "id": "A0A9J7FIG9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FIG9", "type": "external" } ], "mass": 60741.0, "length": 541, "protein_name": "Adenine DNA glycosylase", "gene_name": "Mutyh", "organism": "Hamster", "refseq_name": "adenine DNA glycosylase isoform X1", "refseq_ac": [ { "id": "XP_016821091", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016821091", "type": "external" } ], "gene_names_uniprotkb": "Mutyh", "gene_names_refseq": "Mutyh", "protein_names_uniprotkb": "Adenine DNA glycosylase; 3.2.2.31", "protein_names_refseq": "adenine DNA glycosylase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100752384)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613647.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Adenine glycosylase active on G-A mispairs., [UniProtKB, UniProtKB, UniProtKB]; Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2-OH-A DNA glycosylase activities., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0032357 oxidized purine DNA binding;GO:0034039 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0000701 purine-specific mismatch base pair DNA N-glycosylase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005739 mitochondrion;GO:0005634 nucleus", "go_biological_process": "GO:0006284 base-excision repair;GO:0006298 mismatch repair;GO:0060546 negative regulation of necroptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FIG9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FPG9-1", "uniprot_id": [ { "id": "A0A9J7FPG9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FPG9", "type": "external" } ], "mass": 84919.0, "length": 758, "protein_name": "Lysyl oxidase homolog 4", "gene_name": "Loxl4", "organism": "Hamster", "refseq_name": "lysyl oxidase homolog 4 isoform X1", "refseq_ac": [ { "id": "XP_003497815", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497815", "type": "external" } ], "gene_names_uniprotkb": "Loxl4", "gene_names_refseq": "Loxl4", "protein_names_uniprotkb": "Lysyl oxidase homolog 4; 1.4.3.13; Lysyl oxidase-like protein 4; Lysyl oxidase-related protein C", "protein_names_refseq": "lysyl oxidase homolog 4 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100761424)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613664.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the oxidative deamination of lysine and hydroxylysine residues in collagen and elastin, resulting in the formation of covalent cross-linkages, and the stabilization of collagen and elastin fibers., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.4.3.13", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.13", "type": "external" } ], "go_molecular_function": "GO:0005507 copper ion binding;GO:0004720 protein-lysine 6-oxidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0030199 collagen fibril organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FPG9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FQA1-1", "uniprot_id": [ { "id": "A0A9J7FQA1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FQA1", "type": "external" } ], "mass": 50149.0, "length": 446, "protein_name": "Beta-1,4-galactosyltransferase", "gene_name": "B4galt7", "organism": "Hamster", "refseq_name": "beta-1,4-galactosyltransferase 7 isoform X1", "refseq_ac": [ { "id": "XP_007621324", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007621324", "type": "external" } ], "gene_names_uniprotkb": "B4galt7", "gene_names_refseq": "B4galt7", "protein_names_uniprotkb": "Beta-1,4-galactosyltransferase; 2.4.1.-; Beta-1,4-GalTase", "protein_names_refseq": "beta-1,4-galactosyltransferase 7 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100769652)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613681.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Required for the biosynthesis of the tetrasaccharide linkage region of proteoglycans, especially for small proteoglycans in skin fibroblasts., [UniProtKB, UniProtKB, UniProtKB]; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.-", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0046525 xylosylprotein 4-beta-galactosyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0032580 Golgi cisterna membrane;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0006024 glycosaminoglycan biosynthetic process;GO:0030166 proteoglycan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FQA1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FDV1-1", "uniprot_id": [ { "id": "A0A9J7FDV1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FDV1", "type": "external" } ], "mass": 40143.0, "length": 356, "protein_name": "Cyclin-dependent kinase 7", "gene_name": "Cdk7", "organism": "Hamster", "refseq_name": "cyclin-dependent kinase 7 isoform X1", "refseq_ac": [ { "id": "XP_027257403", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257403", "type": "external" } ], "gene_names_uniprotkb": "Cdk7", "gene_names_refseq": "Cdk7", "protein_names_uniprotkb": "Cyclin-dependent kinase 7; 2.7.11.22; 2.7.11.23; Cell division protein kinase 7; TFIIH basal transcription factor complex kinase subunit", "protein_names_refseq": "cyclin-dependent kinase 7 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100769780)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008094 ATP-dependent activity, acting on DNA;GO:0004693 cyclin-dependent protein serine/threonine kinase activity;GO:0140836 RNA polymerase II CTD heptapeptide repeat S5 kinase activity;GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0001650 fibrillar center;GO:0070985 transcription factor TFIIK complex;GO:0000439 transcription factor TFIIH core complex;GO:0070516 CAK-ERCC2 complex", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0051301 cell division;GO:0050821 protein stabilization;GO:0006367 transcription initiation at RNA polymerase II promoter;GO:2000045 regulation of G1/S transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FDV1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FJA0-1", "uniprot_id": [ { "id": "A0A9J7FJA0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FJA0", "type": "external" } ], "mass": 77774.0, "length": 693, "protein_name": "Adhesion G-protein coupled receptor G1", "gene_name": "Adgrg1", "organism": "Hamster", "refseq_name": "adhesion G-protein coupled receptor G1 isoform X1", "refseq_ac": [ { "id": "XP_007648638", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007648638", "type": "external" } ], "gene_names_uniprotkb": "Adgrg1", "gene_names_refseq": "Adgrg1", "protein_names_uniprotkb": "Adhesion G-protein coupled receptor G1; G-protein coupled receptor 56", "protein_names_refseq": "adhesion G-protein coupled receptor G1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100764884)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614770.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0008201 heparin binding;GO:0005518 collagen binding;GO:0050840 extracellular matrix binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0045121 membrane raft;GO:0097451 glial limiting end-foot", "go_biological_process": "GO:0001525 angiogenesis;GO:0007155 cell adhesion;GO:0007166 cell surface receptor signaling pathway;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0008285 negative regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FJA0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FSM6-1", "uniprot_id": [ { "id": "A0A9J7FSM6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FSM6", "type": "external" } ], "mass": 80769.0, "length": 699, "protein_name": "G protein-coupled receptor kinase", "gene_name": "Grk2", "organism": "Hamster", "refseq_name": "beta-adrenergic receptor kinase 1 isoform X1", "refseq_ac": [ { "id": "XP_007648790", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007648790", "type": "external" } ], "gene_names_uniprotkb": "Grk2", "gene_names_refseq": "Grk2", "protein_names_uniprotkb": "G protein-coupled receptor kinase; 2.7.11.-", "protein_names_refseq": "beta-adrenergic receptor kinase 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100762552)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614797.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_007648790.1. COMPLETENESS: full length., [RefSeq]; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Phosphorylates catecholamine-activated ADRB2 to regulate physiological cardiomyocyte contraction rate responses. Also phosphorylates ligand-bound C3a and C5a anaphylatoxin receptors (C3AR1 and C5AR1, respectively), leading to receptor desensitization. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner. Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by facilitating the trafficking of SMO into the cilium and the stimulation of SMO activity. Inhibits relaxation of airway smooth muscle in response to blue light., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004703 G protein-coupled receptor kinase activity;GO:0047696 beta-adrenergic receptor kinase activity;GO:0031755 Edg-2 lysophosphatidic acid receptor binding;GO:0001664 G protein-coupled receptor binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0098794 postsynapse;GO:0098793 presynapse;GO:0032473 cytoplasmic side of mitochondrial outer membrane", "go_biological_process": "GO:0031623 receptor internalization;GO:0060048 cardiac muscle contraction;GO:0046718 symbiont entry into host cell;GO:0002029 desensitization of G protein-coupled receptor signaling pathway;GO:0003108 negative regulation of the force of heart contraction by chemical signal", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FSM6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FCI7-1", "uniprot_id": [ { "id": "A0A9J7FCI7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FCI7", "type": "external" } ], "mass": 43246.0, "length": 395, "protein_name": "Zinc phosphodiesterase ELAC protein 1", "gene_name": "Elac1", "organism": "Hamster", "refseq_name": "zinc phosphodiesterase ELAC protein 1 isoform X2", "refseq_ac": [ { "id": "XP_027253675", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253675", "type": "external" } ], "gene_names_uniprotkb": "Elac1", "gene_names_refseq": "Elac1", "protein_names_uniprotkb": "Zinc phosphodiesterase ELAC protein 1; 3.1.26.11; ElaC homolog protein 1; Ribonuclease Z 1; tRNA 3 endonuclease 1; tRNase Z 1", "protein_names_refseq": "zinc phosphodiesterase ELAC protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100771025)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Specifically involved in tRNA repair: acts downstream of the ribosome-associated quality control (RQC) pathway by removing a 2',3'-cyclic phosphate from tRNAs following cleavage by ANKZF1. tRNAs are then processed by TRNT1., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0042781 3'-tRNA processing endoribonuclease activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005634 nucleus", "go_biological_process": "GO:0072344 rescue of stalled ribosome", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FCI7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FG26-1", "uniprot_id": [ { "id": "A0A9J7FG26_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FG26", "type": "external" } ], "mass": 189147.0, "length": 1720, "protein_name": "PR domain zinc finger protein 2", "gene_name": "Prdm2", "organism": "Hamster", "refseq_name": "PR domain zinc finger protein 2 isoform X1", "refseq_ac": [ { "id": "XP_007651943", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651943", "type": "external" } ], "gene_names_uniprotkb": "Prdm2", "gene_names_refseq": "Prdm2", "protein_names_uniprotkb": "PR domain zinc finger protein 2; 2.1.1.355; PR domain-containing protein 2; Retinoblastoma protein-interacting zinc finger protein; Zinc finger protein RIZ", "protein_names_refseq": "PR domain zinc finger protein 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:103158597)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 127 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615935.1) and transcript sequence (IACG01088101.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007651943.1. COMPLETENESS: full length., [RefSeq]; S-adenosyl-L-methionine-dependent histone methyltransferase that specifically methylates 'Lys-9' of histone H3. May function as a DNA-binding transcription factor. Binds to the macrophage-specific TPA-responsive element (MTE) of the HMOX1 (heme oxygenase 1) gene and may act as a transcriptional activator of this gene., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.355", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.355", "type": "external" }, { "id": "2.1.1.359", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.359", "type": "external" }, { "id": "2.1.1.354", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.354", "type": "external" }, { "id": "2.1.1.362", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.362", "type": "external" }, { "id": "2.1.1.361", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.361", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042054 histone methyltransferase activity;GO:0003677 DNA binding;GO:0140949 histone H3K9 trimethyltransferase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0010468 regulation of gene expression;GO:0006351 DNA-templated transcription;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FG26-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FD38-1", "uniprot_id": [ { "id": "A0A9J7FD38_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FD38", "type": "external" } ], "mass": 71089.0, "length": 640, "protein_name": "Estrogen receptor", "gene_name": "Esr1", "organism": "Hamster", "refseq_name": "estrogen receptor isoform X2", "refseq_ac": [ { "id": "XP_027256818", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256818", "type": "external" } ], "gene_names_uniprotkb": "Esr1", "gene_names_refseq": "Esr1", "protein_names_uniprotkb": "Estrogen receptor; ER-alpha; ER; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1", "protein_names_refseq": "estrogen receptor isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100768474)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001093 TFIIB-class transcription factor binding;GO:0034056 estrogen response element binding;GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0019901 protein kinase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0000791 euchromatin;GO:0032991 protein-containing complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0010629 negative regulation of gene expression;GO:0042127 regulation of cell population proliferation;GO:0048863 stem cell differentiation;GO:0043124 negative regulation of canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FD38-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FAT7-1", "uniprot_id": [ { "id": "A0A9J7FAT7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FAT7", "type": "external" } ], "mass": 53772.0, "length": 475, "protein_name": "E3 ubiquitin-protein ligase RNF14", "gene_name": "Rnf14", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase RNF14 isoform X1", "refseq_ac": [ { "id": "XP_003508239", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508239", "type": "external" } ], "gene_names_uniprotkb": "Rnf14", "gene_names_refseq": "Rnf14", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RNF14; 2.3.2.31; RING finger protein 14", "protein_names_refseq": "E3 ubiquitin-protein ligase RNF14 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100751183)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 1727 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614499.1) and transcript sequence (IACG01040116.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003508239.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0006351 DNA-templated transcription;GO:0060828 regulation of canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FAT7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FAK3-1", "uniprot_id": [ { "id": "A0A9J7FAK3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FAK3", "type": "external" } ], "mass": 102434.0, "length": 900, "protein_name": "Pre-mRNA-processing factor 40 homolog B", "gene_name": "Prpf40b", "organism": "Hamster", "refseq_name": "pre-mRNA-processing factor 40 homolog B isoform X1", "refseq_ac": [ { "id": "XP_016818654", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016818654", "type": "external" } ], "gene_names_uniprotkb": "Prpf40b", "gene_names_refseq": "Prpf40b", "protein_names_uniprotkb": "Pre-mRNA-processing factor 40 homolog B; Huntingtin yeast partner C; Huntingtin-interacting protein C", "protein_names_refseq": "pre-mRNA-processing factor 40 homolog B isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100766649)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 182 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615965.1) and transcript sequence (IACG01019243.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_016818654.1. COMPLETENESS: full length., [RefSeq]; May be involved in pre-mRNA splicing., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005685 U1 snRNP;GO:0016607 nuclear speck;GO:0016363 nuclear matrix;GO:0071004 U2-type prespliceosome", "go_biological_process": "GO:0045292 mRNA cis splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FAK3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F928-1", "uniprot_id": [ { "id": "A0A9J7F928_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F928", "type": "external" } ], "mass": 90898.0, "length": 831, "protein_name": "Phosphodiesterase", "gene_name": "Pde4c", "organism": "Hamster", "refseq_name": "cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X2", "refseq_ac": [ { "id": "XP_027250535", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250535", "type": "external" } ], "gene_names_uniprotkb": "Pde4c", "gene_names_refseq": "Pde4c", "protein_names_uniprotkb": "Phosphodiesterase; 3.1.4.-", "protein_names_refseq": "cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100770327)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 20% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027250535.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" }, { "id": "3.1.4.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.53", "type": "external" }, { "id": "3.1.4.17", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.17", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity", "go_cellular_component": "", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F928-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F9X2-1", "uniprot_id": [ { "id": "A0A9J7F9X2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F9X2", "type": "external" } ], "mass": 140997.0, "length": 1278, "protein_name": "[histone H3]-lysine(9) N-methyltransferase", "gene_name": "Prdm16", "organism": "Hamster", "refseq_name": "histone-lysine N-methyltransferase PRDM16 isoform X4", "refseq_ac": [ { "id": "XP_027254287", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254287", "type": "external" } ], "gene_names_uniprotkb": "Prdm16", "gene_names_refseq": "Prdm16", "protein_names_uniprotkb": "[histone H3]-lysine(9) N-methyltransferase; 2.1.1.367", "protein_names_refseq": "histone-lysine N-methyltransferase PRDM16 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100762301)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0140948 histone H3K9 monomethyltransferase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0098727 maintenance of cell number;GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0045892 negative regulation of DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F9X2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F985-1", "uniprot_id": [ { "id": "A0A9J7F985_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F985", "type": "external" } ], "mass": 91648.0, "length": 785, "protein_name": "Cyclin-dependent kinase 11B", "gene_name": "LOC118237656", "organism": "Hamster", "refseq_name": "cyclin-dependent kinase 11B isoform X2", "refseq_ac": [ { "id": "XP_027254339", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254339", "type": "external" } ], "gene_names_uniprotkb": "LOC118237656", "gene_names_refseq": "LOC118237656", "protein_names_uniprotkb": "Cyclin-dependent kinase 11B; 2.7.11.22; 2.7.11.23; Cell division cycle 2-like protein kinase 1; Cell division protein kinase 11; Cyclin-dependent kinase 11; Galactosyltransferase-associated protein kinase p58/GTA; PITSLRE serine/threonine-protein kinase CDC2L1", "protein_names_refseq": "cyclin-dependent kinase 11B isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:118237656)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004693 cyclin-dependent protein serine/threonine kinase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0007346 regulation of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F985-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F9I1-1", "uniprot_id": [ { "id": "A0A9J7F9I1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F9I1", "type": "external" } ], "mass": 81245.0, "length": 746, "protein_name": "protein acetyllysine N-acetyltransferase", "gene_name": "Sirt1", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: NAD-dependent protein deacetylase sirtuin-1 isoform X2", "refseq_ac": [ { "id": "XP_027250839", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250839", "type": "external" } ], "gene_names_uniprotkb": "Sirt1", "gene_names_refseq": "Sirt1", "protein_names_uniprotkb": "protein acetyllysine N-acetyltransferase; 2.3.1.286", "protein_names_refseq": "LOW QUALITY PROTEIN: NAD-dependent protein deacetylase sirtuin-1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763298)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 3 indels ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027250839.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.-", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "2.3.1.286", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.286", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0003714 transcription corepressor activity;GO:0070403 NAD+ binding;GO:0002039 p53 binding;GO:0017136 histone deacetylase activity, NAD-dependent", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0033553 rDNA heterochromatin;GO:0005637 nuclear inner membrane", "go_biological_process": "GO:0042981 regulation of apoptotic process;GO:0045595 regulation of cell differentiation;GO:0051239 regulation of multicellular organismal process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F9I1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F9J0-1", "uniprot_id": [ { "id": "A0A9J7F9J0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F9J0", "type": "external" } ], "mass": 117803.0, "length": 1086, "protein_name": "Voltage-gated inwardly rectifying potassium channel KCNH3", "gene_name": "Kcnh3", "organism": "Hamster", "refseq_name": "potassium voltage-gated channel subfamily H member 3 isoform X2", "refseq_ac": [ { "id": "XP_027252319", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027252319", "type": "external" } ], "gene_names_uniprotkb": "Kcnh3", "gene_names_refseq": "Kcnh3", "protein_names_uniprotkb": "Voltage-gated inwardly rectifying potassium channel KCNH3; Ether-a-go-go-like potassium channel 2; Potassium voltage-gated channel subfamily H member 3; Voltage-gated potassium channel subunit Kv12.2", "protein_names_refseq": "potassium voltage-gated channel subfamily H member 3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762492)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Pore-forming (alpha) subunit of a voltage-gated inwardly rectifying potassium channel. Charactherized by a fast rate of activation during depolarization followed by a rapid inactivation at much more depolarized value causing inward rectification due to a C-type inactivation mechanism. Exhibits a rapid recovery from inactivation., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005242 inward rectifier potassium channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0034702 monoatomic ion channel complex", "go_biological_process": "GO:0042391 regulation of membrane potential", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F9J0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FEN1-1", "uniprot_id": [ { "id": "A0A9J7FEN1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FEN1", "type": "external" } ], "mass": 64426.0, "length": 592, "protein_name": "Eyes absent homolog", "gene_name": "Eya1", "organism": "Hamster", "refseq_name": "eyes absent homolog 1 isoform X1", "refseq_ac": [ { "id": "XP_027254623", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254623", "type": "external" } ], "gene_names_uniprotkb": "Eya1", "gene_names_refseq": "Eya1", "protein_names_uniprotkb": "Eyes absent homolog; 3.1.3.48", "protein_names_refseq": "eyes absent homolog 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100772860)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006281 DNA repair;GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0045739 positive regulation of DNA repair;GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FEN1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FDD3-1", "uniprot_id": [ { "id": "A0A9J7FDD3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FDD3", "type": "external" } ], "mass": 66575.0, "length": 618, "protein_name": "E3 ubiquitin-protein ligase RNF217", "gene_name": "Rnf217", "organism": "Hamster", "refseq_name": "probable E3 ubiquitin-protein ligase RNF217 isoform X3", "refseq_ac": [ { "id": "XP_027254237", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254237", "type": "external" } ], "gene_names_uniprotkb": "Rnf217", "gene_names_refseq": "Rnf217", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RNF217; 2.3.2.31; IBR domain-containing protein 1; RING finger protein 217", "protein_names_refseq": "probable E3 ubiquitin-protein ligase RNF217 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100762229)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates the degradation of the iron exporter ferroportin/SLC40A1 and thus regulates iron homeostasis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FDD3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F9Z8-1", "uniprot_id": [ { "id": "A0A9J7F9Z8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F9Z8", "type": "external" } ], "mass": 52998.0, "length": 466, "protein_name": "CTP synthase", "gene_name": "Ctps1", "organism": "Hamster", "refseq_name": "CTP synthase 1 isoform X2", "refseq_ac": [ { "id": "XP_027254946", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254946", "type": "external" } ], "gene_names_uniprotkb": "Ctps1", "gene_names_refseq": "Ctps1", "protein_names_uniprotkb": "CTP synthase; 6.3.4.2; UTP--ammonia ligase", "protein_names_refseq": "CTP synthase 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.3.4.2", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.4.2", "type": "external" }, { "id": "3.5.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0003883 CTP synthase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0097268 cytoophidium", "go_biological_process": "GO:0044210 'de novo' CTP biosynthetic process;GO:0019856 pyrimidine nucleobase biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F9Z8-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FA23-1", "uniprot_id": [ { "id": "A0A9J7FA23_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FA23", "type": "external" } ], "mass": 57074.0, "length": 524, "protein_name": "Succinyl-CoA:3-ketoacid-coenzyme A transferase", "gene_name": "LOC100772647", "organism": "Hamster", "refseq_name": "succinyl-CoA:3-ketoacid coenzyme A transferase 2A, mitochondrial isoform X2", "refseq_ac": [ { "id": "XP_027254989", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254989", "type": "external" } ], "gene_names_uniprotkb": "LOC100772647", "gene_names_refseq": "LOC100772647", "protein_names_uniprotkb": "Succinyl-CoA:3-ketoacid-coenzyme A transferase; 2.8.3.5", "protein_names_refseq": "succinyl-CoA:3-ketoacid coenzyme A transferase 2A, mitochondrial isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772647)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.8.3.5", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.3.5", "type": "external" } ], "go_molecular_function": "GO:0008260 succinyl-CoA:3-oxo-acid CoA-transferase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0046952 ketone body catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FA23-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FA89-1", "uniprot_id": [ { "id": "A0A9J7FA89_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FA89", "type": "external" } ], "mass": 68878.0, "length": 627, "protein_name": "Voltage-gated potassium channel KCNC4", "gene_name": "Kcnc4", "organism": "Hamster", "refseq_name": "potassium voltage-gated channel subfamily C member 4 isoform X2", "refseq_ac": [ { "id": "XP_027251248", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251248", "type": "external" } ], "gene_names_uniprotkb": "Kcnc4", "gene_names_refseq": "Kcnc4", "protein_names_uniprotkb": "Voltage-gated potassium channel KCNC4; Potassium voltage-gated channel subfamily C member 4; Voltage-gated potassium channel subunit Kv3.4", "protein_names_refseq": "potassium voltage-gated channel subfamily C member 4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100761530)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Voltage-gated potassium channel that opens in response to the voltage difference across the membrane, forming a potassium-selective channel through which potassium ions pass in accordance with their electrochemical gradient. The channel displays rapid activation and inactivation kinetics., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005251 delayed rectifier potassium channel activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0043679 axon terminus;GO:0045211 postsynaptic membrane;GO:0008076 voltage-gated potassium channel complex;GO:0032809 neuronal cell body membrane;GO:0042734 presynaptic membrane", "go_biological_process": "GO:0051260 protein homooligomerization;GO:0001508 action potential", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FA89-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FAF1-1", "uniprot_id": [ { "id": "A0A9J7FAF1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FAF1", "type": "external" } ], "mass": 297138.0, "length": 2571, "protein_name": "Centromere-associated protein E", "gene_name": "Cenpe", "organism": "Hamster", "refseq_name": "centromere-associated protein E isoform X2", "refseq_ac": [ { "id": "XP_027251551", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251551", "type": "external" } ], "gene_names_uniprotkb": "Cenpe", "gene_names_refseq": "Cenpe", "protein_names_uniprotkb": "Centromere-associated protein E; Centromere protein E", "protein_names_refseq": "centromere-associated protein E isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100771167)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0003777 microtubule motor activity;GO:0043515 kinetochore binding", "go_cellular_component": "GO:0005874 microtubule;GO:0000776 kinetochore", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0008608 attachment of spindle microtubules to kinetochore;GO:0007018 microtubule-based movement;GO:0030071 regulation of mitotic metaphase/anaphase transition;GO:0007051 spindle organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FAF1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FAH5-1", "uniprot_id": [ { "id": "A0A9J7FAH5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FAH5", "type": "external" } ], "mass": 40382.0, "length": 373, "protein_name": "Enoyl-[acyl-carrier-protein] reductase, mitochondrial", "gene_name": "Mecr", "organism": "Hamster", "refseq_name": "enoyl-[acyl-carrier-protein] reductase, mitochondrial isoform X1", "refseq_ac": [ { "id": "XP_027255268", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255268", "type": "external" } ], "gene_names_uniprotkb": "Mecr", "gene_names_refseq": "Mecr", "protein_names_uniprotkb": "Enoyl-[acyl-carrier-protein] reductase, mitochondrial; 1.3.1.104; 2-enoyl thioester reductase; Nuclear receptor-binding factor 1", "protein_names_refseq": "enoyl-[acyl-carrier-protein] reductase, mitochondrial isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100767445)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II). Fatty acid chain elongation in mitochondria uses acyl carrier protein (ACP) as an acyl group carrier, but the enzyme accepts both ACP and CoA thioesters as substrates in vitro. Displays a preference for medium-chain over short- and long-chain substrates. May provide the octanoyl chain used for lipoic acid biosynthesis, regulating protein lipoylation and mitochondrial respiratory activity particularly in Purkinje cells. Involved in iron homeostasis; affecting Fe-S cluster assembly and ceramide metabolism. Required for proper morphology and bioenergetic functions of mitochondria. Required for maintenance of neurons., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.3.1.104", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.104", "type": "external" }, { "id": "1.1.1.100", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.100", "type": "external" }, { "id": "1.3.1.39", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.39", "type": "external" }, { "id": "2.3.1.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.38", "type": "external" }, { "id": "2.3.1.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.39", "type": "external" }, { "id": "2.3.1.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.41", "type": "external" }, { "id": "2.3.1.85", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.85", "type": "external" }, { "id": "3.1.2.14", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.14", "type": "external" }, { "id": "4.2.1.59", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.59", "type": "external" } ], "go_molecular_function": "GO:0141148 enoyl-[acyl-carrier-protein] reductase (NADPH) activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006633 fatty acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FAH5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FAL6-1", "uniprot_id": [ { "id": "A0A9J7FAL6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FAL6", "type": "external" } ], "mass": 21506.0, "length": 194, "protein_name": "Group XIIA secretory phospholipase A2", "gene_name": "Pla2g12a", "organism": "Hamster", "refseq_name": "group XIIA secretory phospholipase A2 isoform X2", "refseq_ac": [ { "id": "XP_027251505", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251505", "type": "external" } ], "gene_names_uniprotkb": "Pla2g12a", "gene_names_refseq": "Pla2g12a", "protein_names_uniprotkb": "Group XIIA secretory phospholipase A2; 3.1.1.4; Phosphatidylcholine 2-acylhydrolase 12A", "protein_names_refseq": "group XIIA secretory phospholipase A2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767324)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Does not exhibit detectable activity toward sn-2-arachidonoyl- or linoleoyl-phosphatidylcholine or -phosphatidylethanolamine., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0004623 phospholipase A2 activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005737 cytoplasm", "go_biological_process": "GO:0016042 lipid catabolic process;GO:0050482 arachidonate secretion;GO:0006644 phospholipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FAL6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FAQ0-1", "uniprot_id": [ { "id": "A0A9J7FAQ0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FAQ0", "type": "external" } ], "mass": 26636.0, "length": 245, "protein_name": "Dehydrogenase/reductase SDR family member 6", "gene_name": "Bdh2", "organism": "Hamster", "refseq_name": "3-hydroxybutyrate dehydrogenase type 2 isoform X2", "refseq_ac": [ { "id": "XP_027251559", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251559", "type": "external" } ], "gene_names_uniprotkb": "Bdh2", "gene_names_refseq": "Bdh2", "protein_names_uniprotkb": "Dehydrogenase/reductase SDR family member 6; (R)-beta-hydroxybutyrate dehydrogenase; 1.1.1.104; 1.1.1.30; 3-hydroxybutyrate dehydrogenase type 2; 4-oxo-L-proline reductase; Oxidoreductase UCPA; Short chain dehydrogenase/reductase family 15C member 1", "protein_names_refseq": "3-hydroxybutyrate dehydrogenase type 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100766065)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; NAD(H)-dependent dehydrogenase/reductase with a preference for cyclic substrates. Catalyzes stereoselective conversion of 4-oxo-L-proline to cis-4-hydroxy-L-proline, likely a detoxification mechanism for ketoprolines. Mediates the formation of 2,5-dihydroxybenzoate (2,5-DHBA), a siderophore that chelates free cytoplasmic iron and associates with LCN2, thereby regulating iron transport and homeostasis while protecting cells against free radical-induced oxidative stress. The iron-siderophore complex is imported into mitochondria, providing an iron source for mitochondrial metabolic processes in particular heme synthesis. May act as a 3-hydroxybutyrate dehydrogenase., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.1.30", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.30", "type": "external" }, { "id": "1.1.1.104", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.104", "type": "external" } ], "go_molecular_function": "GO:0003858 3-hydroxybutyrate dehydrogenase activity;GO:0016617 4-oxoproline reductase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0019290 siderophore biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FAQ0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FAR1-1", "uniprot_id": [ { "id": "A0A9J7FAR1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FAR1", "type": "external" } ], "mass": 74057.0, "length": 668, "protein_name": "Exostosin-like 1", "gene_name": "Extl1", "organism": "Hamster", "refseq_name": "exostosin-like 1 isoform X1", "refseq_ac": [ { "id": "XP_027255435", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255435", "type": "external" } ], "gene_names_uniprotkb": "Extl1", "gene_names_refseq": "Extl1", "protein_names_uniprotkb": "Exostosin-like 1; 2.4.1.224; Exostosin-L; Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Multiple exostosis-like protein", "protein_names_refseq": "exostosin-like 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100770000)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Glycosyltransferase required for the biosynthesis of heparan-sulfate (HS). Transfers N-acetyl-alpha-D-glucosamine to the nascent HS chain (GlcNAcT-II activity). Appears to lack GlcNAcT I and GlcAT-II activities., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.224", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.224", "type": "external" } ], "go_molecular_function": "GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0015012 heparan sulfate proteoglycan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FAR1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FAS2-1", "uniprot_id": [ { "id": "A0A9J7FAS2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FAS2", "type": "external" } ], "mass": 99700.0, "length": 895, "protein_name": "Microsomal triglyceride transfer protein large subunit", "gene_name": "Mttp", "organism": "Hamster", "refseq_name": "microsomal triglyceride transfer protein large subunit isoform X2", "refseq_ac": [ { "id": "XP_027251602", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251602", "type": "external" } ], "gene_names_uniprotkb": "Mttp", "gene_names_refseq": "Mttp", "protein_names_uniprotkb": "Microsomal triglyceride transfer protein large subunit", "protein_names_refseq": "microsomal triglyceride transfer protein large subunit isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100759278)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces. Required for the assembly and secretion of plasma lipoproteins that contain apolipoprotein B. May be involved in regulating cholesteryl ester biosynthesis in cells that produce lipoproteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008289 lipid binding;GO:1904121 phosphatidylethanolamine transfer activity;GO:0120020 cholesterol transfer activity;GO:0140344 triglyceride transfer activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0042157 lipoprotein metabolic process;GO:0042632 cholesterol homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FAS2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FCZ1-1", "uniprot_id": [ { "id": "A0A9J7FCZ1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FCZ1", "type": "external" } ], "mass": 35493.0, "length": 334, "protein_name": "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "gene_name": "Hmgcl", "organism": "Hamster", "refseq_name": "hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X2", "refseq_ac": [ { "id": "XP_027255512", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255512", "type": "external" } ], "gene_names_uniprotkb": "Hmgcl", "gene_names_refseq": "Hmgcl", "protein_names_uniprotkb": "Hydroxymethylglutaryl-CoA lyase, mitochondrial; 3-hydroxy-3-methylglutarate-CoA lyase; 4.1.3.4", "protein_names_refseq": "hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100755385)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.1.3.4", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.3.4", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004419 hydroxymethylglutaryl-CoA lyase activity;GO:0000287 magnesium ion binding;GO:0030145 manganese ion binding;GO:0005198 structural molecule activity", "go_cellular_component": "GO:0005759 mitochondrial matrix;GO:0005777 peroxisome;GO:0032991 protein-containing complex", "go_biological_process": "GO:0046951 ketone body biosynthetic process;GO:0006552 L-leucine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FCZ1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FAY9-1", "uniprot_id": [ { "id": "A0A9J7FAY9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FAY9", "type": "external" } ], "mass": 61192.0, "length": 569, "protein_name": "Anti-Muellerian hormone type-2 receptor", "gene_name": "Amhr2", "organism": "Hamster", "refseq_name": "anti-Muellerian hormone type-2 receptor", "refseq_ac": [ { "id": "XP_027252500", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027252500", "type": "external" } ], "gene_names_uniprotkb": "Amhr2", "gene_names_refseq": "Amhr2", "protein_names_uniprotkb": "Anti-Muellerian hormone type-2 receptor; 2.7.11.30; Anti-Muellerian hormone type II receptor; MIS type II receptor", "protein_names_refseq": "anti-Muellerian hormone type-2 receptor", "tax_id": 10029, "disease": "", "pathway": " (cge:100772657)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 5% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027252500.1. COMPLETENESS: full length., [RefSeq]; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.30", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.30", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0005024 transforming growth factor beta receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0030509 BMP signaling pathway;GO:0007548 sex differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FAY9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FAZ8-1", "uniprot_id": [ { "id": "A0A9J7FAZ8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FAZ8", "type": "external" } ], "mass": 16248.0, "length": 147, "protein_name": "Cytidine deaminase", "gene_name": "Cda", "organism": "Hamster", "refseq_name": "cytidine deaminase", "refseq_ac": [ { "id": "XP_003500899", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500899", "type": "external" } ], "gene_names_uniprotkb": "Cda", "gene_names_refseq": "Cda", "protein_names_uniprotkb": "Cytidine deaminase; 3.5.4.5; Cytidine aminohydrolase", "protein_names_refseq": "cytidine deaminase", "tax_id": 10029, "disease": "", "pathway": " (cge:100754972)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613816.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.5.4.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.5", "type": "external" } ], "go_molecular_function": "GO:0004126 cytidine deaminase activity;GO:0008270 zinc ion binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0055086 nucleobase-containing small molecule metabolic process;GO:0072527 pyrimidine-containing compound metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FAZ8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FAZ9-1", "uniprot_id": [ { "id": "A0A9J7FAZ9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FAZ9", "type": "external" } ], "mass": 50226.0, "length": 476, "protein_name": "Tumor necrosis factor receptor superfamily member 1B isoform X2", "gene_name": "Tnfrsf1b", "organism": "Hamster", "refseq_name": "tumor necrosis factor receptor superfamily member 1B isoform X2", "refseq_ac": [ { "id": "XP_027253963", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253963", "type": "external" } ], "gene_names_uniprotkb": "Tnfrsf1b", "gene_names_refseq": "Tnfrsf1b", "protein_names_uniprotkb": "Tumor necrosis factor receptor superfamily member 1B isoform X2", "protein_names_refseq": "tumor necrosis factor receptor superfamily member 1B isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774542)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043120 tumor necrosis factor binding;GO:0005031 tumor necrosis factor receptor activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0006954 inflammatory response;GO:0048714 positive regulation of oligodendrocyte differentiation;GO:0051044 positive regulation of membrane protein ectodomain proteolysis;GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage;GO:0097191 extrinsic apoptotic signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FAZ9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FFW2-1", "uniprot_id": [ { "id": "A0A9J7FFW2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FFW2", "type": "external" } ], "mass": 34438.0, "length": 311, "protein_name": "F-actin-capping protein subunit beta", "gene_name": "Capzb", "organism": "Hamster", "refseq_name": "F-actin-capping protein subunit beta isoform X12", "refseq_ac": [ { "id": "XP_027255635", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255635", "type": "external" } ], "gene_names_uniprotkb": "Capzb", "gene_names_refseq": "Capzb", "protein_names_uniprotkb": "F-actin-capping protein subunit beta", "protein_names_refseq": "F-actin-capping protein subunit beta isoform X12", "tax_id": 10029, "disease": "", "pathway": " (cge:100755876)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization. Forms, with CAPZB, the barbed end of the fast growing ends of actin filaments in the dynactin complex and stabilizes dynactin structure. The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding", "go_cellular_component": "GO:0008290 F-actin capping protein complex;GO:0030017 sarcomere;GO:0005903 brush border;GO:0014069 postsynaptic density;GO:0016020 membrane", "go_biological_process": "GO:0000902 cell morphogenesis;GO:0030036 actin cytoskeleton organization;GO:0051016 barbed-end actin filament capping;GO:0051490 negative regulation of filopodium assembly;GO:0010591 regulation of lamellipodium assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FFW2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FB28-1", "uniprot_id": [ { "id": "A0A9J7FB28_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FB28", "type": "external" } ], "mass": 200421.0, "length": 1798, "protein_name": "Gamma-tubulin complex component 6", "gene_name": "Tubgcp6", "organism": "Hamster", "refseq_name": "gamma-tubulin complex component 6 isoform X1", "refseq_ac": [ { "id": "XP_027252029", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027252029", "type": "external" } ], "gene_names_uniprotkb": "Tubgcp6", "gene_names_refseq": "Tubgcp6", "protein_names_uniprotkb": "Gamma-tubulin complex component 6", "protein_names_refseq": "gamma-tubulin complex component 6 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100753745)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation. The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051011 microtubule minus-end binding;GO:0043015 gamma-tubulin binding", "go_cellular_component": "GO:0000922 spindle pole;GO:0005813 centrosome;GO:0005874 microtubule;GO:0000930 gamma-tubulin complex", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0007020 microtubule nucleation;GO:0051225 spindle assembly;GO:0051321 meiotic cell cycle;GO:0031122 cytoplasmic microtubule organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FB28-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FB56-1", "uniprot_id": [ { "id": "A0A9J7FB56_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FB56", "type": "external" } ], "mass": 161226.0, "length": 1436, "protein_name": "Receptor-type tyrosine-protein phosphatase U", "gene_name": "Ptpru", "organism": "Hamster", "refseq_name": "receptor-type tyrosine-protein phosphatase U isoform X2", "refseq_ac": [ { "id": "XP_027255265", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255265", "type": "external" } ], "gene_names_uniprotkb": "Ptpru", "gene_names_refseq": "Ptpru", "protein_names_uniprotkb": "Receptor-type tyrosine-protein phosphatase U; 3.1.3.48; Pancreatic carcinoma phosphatase 2; Receptor-type protein-tyrosine phosphatase psi", "protein_names_refseq": "receptor-type tyrosine-protein phosphatase U isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100766961)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Tyrosine-protein phosphatase which dephosphorylates CTNNB1. Regulates CTNNB1 function both in cell adhesion and signaling. May function in cell proliferation and migration and play a role in the maintenance of epithelial integrity. May play a role in megakaryocytopoiesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" } ], "go_molecular_function": "GO:0008013 beta-catenin binding;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0070161 anchoring junction;GO:0016020 membrane", "go_biological_process": "GO:0007155 cell adhesion;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FB56-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FB85-1", "uniprot_id": [ { "id": "A0A9J7FB85_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FB85", "type": "external" } ], "mass": 56383.0, "length": 512, "protein_name": "DAP3-binding cell death enhancer 1", "gene_name": "Dele1", "organism": "Hamster", "refseq_name": "death ligand signal enhancer", "refseq_ac": [ { "id": "XP_007647006", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007647006", "type": "external" } ], "gene_names_uniprotkb": "Dele1", "gene_names_refseq": "Dele1", "protein_names_uniprotkb": "DAP3-binding cell death enhancer 1; DAP3-binding cell death enhancer 1, long form; Death ligand signal enhancer", "protein_names_refseq": "death ligand signal enhancer", "tax_id": 10029, "disease": "", "pathway": " (cge:100774899)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614499.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Protein kinase activator generated by protein cleavage in response to mitochondrial stress, which accumulates in the cytosol and specifically binds to and activates the protein kinase activity of EIF2AK1/HRI. It thereby activates the integrated stress response (ISR): EIF2AK1/HRI activation promotes eIF-2-alpha (EIF2S1) phosphorylation, leading to a decrease in global protein synthesis and the induction of selected genes, including the transcription factor ATF4, the master transcriptional regulator of the ISR. Also acts as an activator of PRKN-independent mitophagy: activates the protein kinase activity of EIF2AK1/HRI in response to mitochondrial damage, promoting eIF-2-alpha (EIF2S1) phosphorylation, leading to mitochondrial localization of EIF2S1 followed by induction of mitophagy., [UniProtKB, UniProtKB]; Protein kinase activator that activates the ISR in response to iron deficiency: iron deficiency impairs mitochondrial import, promoting DELE1 localization at the mitochondrial surface, where it binds and activates EIF2AK1/HRI to trigger the ISR., [UniProtKB, UniProtKB]; Protein kinase activator that acts as a key activator of the integrated stress response (ISR) following various stresses, such as iron deficiency, mitochondrial stress or mitochondrial DNA breaks. Detects impaired protein import and processing in mitochondria, activating the ISR. May also required for the induction of death receptor-mediated apoptosis through the regulation of caspase activation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005743 mitochondrial inner membrane;GO:0005829 cytosol", "go_biological_process": "GO:0006974 DNA damage response;GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FB85-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FGD3-1", "uniprot_id": [ { "id": "A0A9J7FGD3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FGD3", "type": "external" } ], "mass": 349257.0, "length": 3101, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Trio", "organism": "Hamster", "refseq_name": "triple functional domain protein isoform X2", "refseq_ac": [ { "id": "XP_027255859", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255859", "type": "external" } ], "gene_names_uniprotkb": "Trio", "gene_names_refseq": "Trio", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "triple functional domain protein isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772244)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0016301 kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0019898 extrinsic component of membrane", "go_biological_process": "GO:0007411 axon guidance", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FGD3-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FFE8-1", "uniprot_id": [ { "id": "A0A9J7FFE8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FFE8", "type": "external" } ], "mass": 128161.0, "length": 1129, "protein_name": "Telomerase reverse transcriptase", "gene_name": "Tert", "organism": "Hamster", "refseq_name": "telomerase reverse transcriptase isoform X4", "refseq_ac": [ { "id": "XP_027255938", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255938", "type": "external" } ], "gene_names_uniprotkb": "Tert", "gene_names_refseq": "Tert", "protein_names_uniprotkb": "Telomerase reverse transcriptase; 2.7.7.49; Telomerase catalytic subunit", "protein_names_refseq": "telomerase reverse transcriptase isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100774541)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nucleotide telomeric repeat unit, 5'-TTAGGG-3'. The catalytic cycle involves primer binding, primer extension and release of product once the template boundary has been reached or nascent product translocation followed by further extension. More active on substrates containing 2 or 3 telomeric repeats. Telomerase activity is regulated by a number of factors including telomerase complex-associated proteins, chaperones and polypeptide modifiers. Modulates Wnt signaling. Plays important roles in aging and antiapoptosis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.31", "type": "external" }, { "id": "2.7.7.102", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.102", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0042162 telomeric DNA binding;GO:0003720 telomerase activity;GO:0070034 telomerase RNA binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005739 mitochondrion;GO:0016605 PML body;GO:0000781 chromosome, telomeric region;GO:0000333 telomerase catalytic core complex", "go_biological_process": "GO:0007004 telomere maintenance via telomerase", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FFE8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FGM5-1", "uniprot_id": [ { "id": "A0A9J7FGM5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FGM5", "type": "external" } ], "mass": 211981.0, "length": 1868, "protein_name": "CDK5 regulatory subunit-associated protein 2", "gene_name": "Cdk5rap2", "organism": "Hamster", "refseq_name": "CDK5 regulatory subunit-associated protein 2 isoform X1", "refseq_ac": [ { "id": "XP_007647100", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007647100", "type": "external" } ], "gene_names_uniprotkb": "Cdk5rap2", "gene_names_refseq": "Cdk5rap2", "protein_names_uniprotkb": "CDK5 regulatory subunit-associated protein 2", "protein_names_refseq": "CDK5 regulatory subunit-associated protein 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100764684)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614513.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_007647100.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0008017 microtubule binding;GO:0043015 gamma-tubulin binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0097431 mitotic spindle pole;GO:0035371 microtubule plus-end;GO:0000242 pericentriolar material", "go_biological_process": "GO:0007059 chromosome segregation;GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint;GO:0000132 establishment of mitotic spindle orientation;GO:0046600 negative regulation of centriole replication;GO:0001578 microtubule bundle formation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FGM5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FBL1-1", "uniprot_id": [ { "id": "A0A9J7FBL1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FBL1", "type": "external" } ], "mass": 69228.0, "length": 618, "protein_name": "Hyaluronan synthase 1", "gene_name": "LOC113833756", "organism": "Hamster", "refseq_name": "hyaluronan synthase 1", "refseq_ac": [ { "id": "XP_027254478", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254478", "type": "external" } ], "gene_names_uniprotkb": "LOC113833756", "gene_names_refseq": "LOC113833756", "protein_names_uniprotkb": "Hyaluronan synthase 1; 2.4.1.212; Hyaluronate synthase 1; Hyaluronic acid synthase 1", "protein_names_refseq": "hyaluronan synthase 1", "tax_id": 10029, "disease": "", "pathway": " (cge:113833756)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 6% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027254478.1. COMPLETENESS: full length., [RefSeq]; Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential for the synthesis of hyaluronan, a major component of most extracellular matrices that has a structural role in tissue architecture and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction. Also able to catalyze the synthesis of chito-oligosaccharide depending on the substrate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.212", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.212", "type": "external" } ], "go_molecular_function": "GO:0050501 hyaluronan synthase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0085029 extracellular matrix assembly;GO:0030213 hyaluronan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FBL1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FBL3-1", "uniprot_id": [ { "id": "A0A9J7FBL3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FBL3", "type": "external" } ], "mass": 226235.0, "length": 1988, "protein_name": "Sodium channel protein", "gene_name": "Scn8a", "organism": "Hamster", "refseq_name": "sodium channel protein type 8 subunit alpha isoform X8", "refseq_ac": [ { "id": "XP_027252412", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027252412", "type": "external" } ], "gene_names_uniprotkb": "Scn8a", "gene_names_refseq": "Scn8a", "protein_names_uniprotkb": "Sodium channel protein", "protein_names_refseq": "sodium channel protein type 8 subunit alpha isoform X8", "tax_id": 10029, "disease": "", "pathway": " (cge:100764200)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Pore-forming subunit of a voltage-gated sodium channel complex assuming opened or closed conformations in response to the voltage difference across membranes and through which sodium ions selectively pass along their electrochemical gradient. Contributes to neuronal excitability by regulating action potential threshold and propagation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005248 voltage-gated sodium channel activity", "go_cellular_component": "GO:0033268 node of Ranvier;GO:0001518 voltage-gated sodium channel complex", "go_biological_process": "GO:0019228 neuronal action potential;GO:0086010 membrane depolarization during action potential;GO:0021675 nerve development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FBL3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FBP0-1", "uniprot_id": [ { "id": "A0A9J7FBP0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FBP0", "type": "external" } ], "mass": 38744.0, "length": 358, "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "Rnf146", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase RNF146", "refseq_ac": [ { "id": "XP_003509688", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509688", "type": "external" } ], "gene_names_uniprotkb": "Rnf146", "gene_names_refseq": "Rnf146", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase; 2.3.2.27", "protein_names_refseq": "E3 ubiquitin-protein ligase RNF146", "tax_id": 10029, "disease": "", "pathway": " (cge:100760329)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614744.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0072572 poly-ADP-D-ribose binding;GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0016055 Wnt signaling pathway;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0051865 protein autoubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FBP0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FBT0-1", "uniprot_id": [ { "id": "A0A9J7FBT0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FBT0", "type": "external" } ], "mass": 354079.0, "length": 3261, "protein_name": "Striated muscle-specific serine/threonine-protein kinase", "gene_name": "Speg", "organism": "Hamster", "refseq_name": "striated muscle preferentially expressed protein kinase isoform X3", "refseq_ac": [ { "id": "XP_027253098", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253098", "type": "external" } ], "gene_names_uniprotkb": "Speg", "gene_names_refseq": "Speg", "protein_names_uniprotkb": "Striated muscle-specific serine/threonine-protein kinase; 2.7.11.1; Aortic preferentially expressed protein 1", "protein_names_refseq": "striated muscle preferentially expressed protein kinase isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100767885)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 6, "predicted_n_glycosites": 0, "predicted_o_glycosites": 6, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0042692 muscle cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FBT0-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FBW7-1", "uniprot_id": [ { "id": "A0A9J7FBW7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FBW7", "type": "external" } ], "mass": 93498.0, "length": 861, "protein_name": "Integrin beta", "gene_name": "Itgb7", "organism": "Hamster", "refseq_name": "integrin beta-7", "refseq_ac": [ { "id": "XP_003507259", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507259", "type": "external" } ], "gene_names_uniprotkb": "Itgb7", "gene_names_refseq": "Itgb7", "protein_names_uniprotkb": "Integrin beta", "protein_names_refseq": "integrin beta-7", "tax_id": 10029, "disease": "", "pathway": " (cge:100770075)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614339.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003507259.1. COMPLETENESS: full length., [RefSeq]; Integrin ITGA4/ITGB7 (alpha-4/beta-7) (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT). Integrin ITGA4/ITGB7 interacts with the cell surface adhesion molecules MADCAM1 which is normally expressed by the vascular endothelium of the gastrointestinal tract. Also interacts with VCAM1 and fibronectin, an extracellular matrix component. It recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin. Interactions involve the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin. Integrin ITGAE/ITGB7 (alpha-E/beta-7, HML-1) is a receptor for E-cadherin., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005925 focal adhesion;GO:0009986 cell surface;GO:0008305 integrin complex", "go_biological_process": "GO:0007229 integrin-mediated signaling pathway;GO:0007160 cell-matrix adhesion;GO:0033627 cell adhesion mediated by integrin;GO:0098609 cell-cell adhesion;GO:0050900 leukocyte migration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FBW7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FC68-1", "uniprot_id": [ { "id": "A0A9J7FC68_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FC68", "type": "external" } ], "mass": 96982.0, "length": 854, "protein_name": "Trimethylguanosine synthase", "gene_name": "Tgs1", "organism": "Hamster", "refseq_name": "trimethylguanosine synthase isoform X1", "refseq_ac": [ { "id": "XP_027254724", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254724", "type": "external" } ], "gene_names_uniprotkb": "Tgs1", "gene_names_refseq": "Tgs1", "protein_names_uniprotkb": "Trimethylguanosine synthase; Cap-specific guanine-N(2) methyltransferase; Nuclear receptor coactivator 6-interacting protein; PRIP-interacting protein with methyltransferase motif", "protein_names_refseq": "trimethylguanosine synthase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100755697)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0071164 RNA cap trimethylguanosine synthase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0015030 Cajal body", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FC68-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FCB0-1", "uniprot_id": [ { "id": "A0A9J7FCB0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FCB0", "type": "external" } ], "mass": 73610.0, "length": 666, "protein_name": "Malic enzyme", "gene_name": "Me2", "organism": "Hamster", "refseq_name": "NAD-dependent malic enzyme, mitochondrial isoform X1", "refseq_ac": [ { "id": "XP_003506847", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506847", "type": "external" } ], "gene_names_uniprotkb": "Me2", "gene_names_refseq": "Me2", "protein_names_uniprotkb": "Malic enzyme", "protein_names_refseq": "NAD-dependent malic enzyme, mitochondrial isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100771311)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 650 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614296.1) and transcript sequence (IACG01054110.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003506847.2. COMPLETENESS: full length., [RefSeq]; NAD-dependent mitochondrial malic enzyme that catalyzes the oxidative decarboxylation of malate to pyruvate., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.7.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.7.1.5", "type": "external" }, { "id": "4.1.1.112", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.112", "type": "external" }, { "id": "5.3.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.2.2", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0051287 NAD binding;GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity;GO:0004473 malate dehydrogenase (decarboxylating) (NADP+) activity", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006108 malate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FCB0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FCH0-1", "uniprot_id": [ { "id": "A0A9J7FCH0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FCH0", "type": "external" } ], "mass": 61789.0, "length": 534, "protein_name": "Poly(A)-specific ribonuclease PNLDC1", "gene_name": "Pnldc1", "organism": "Hamster", "refseq_name": "poly(A)-specific ribonuclease PNLDC1", "refseq_ac": [ { "id": "XP_027256765", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256765", "type": "external" } ], "gene_names_uniprotkb": "Pnldc1", "gene_names_refseq": "Pnldc1", "protein_names_uniprotkb": "Poly(A)-specific ribonuclease PNLDC1; 3.1.13.4; PARN-like domain-containing protein 1; Poly(A)-specific ribonuclease domain-containing protein 1", "protein_names_refseq": "poly(A)-specific ribonuclease PNLDC1", "tax_id": 10029, "disease": "", "pathway": " (cge:100762328)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; 3'-exoribonuclease that has a preference for poly(A) tails of mRNAs, thereby efficiently degrading poly(A) tails. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs and is also used to silence certain maternal mRNAs translationally during oocyte maturation and early embryonic development. May act as a regulator of multipotency in embryonic stem cells. Is a critical factor for proper spermatogenesis, involved in pre-piRNAs processing to generate mature piRNAs., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0046872 metal ion binding;GO:0004535 poly(A)-specific ribonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0032502 developmental process;GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening;GO:1990431 priRNA 3'-end processing;GO:1990432 siRNA 3'-end processing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FCH0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FCJ0-1", "uniprot_id": [ { "id": "A0A9J7FCJ0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FCJ0", "type": "external" } ], "mass": 113033.0, "length": 999, "protein_name": "Type II inositol 1,4,5-trisphosphate 5-phosphatase", "gene_name": "Inpp5b", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: type II inositol 1,4,5-trisphosphate 5-phosphatase", "refseq_ac": [ { "id": "XP_016830986", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016830986", "type": "external" } ], "gene_names_uniprotkb": "Inpp5b", "gene_names_refseq": "Inpp5b", "protein_names_uniprotkb": "Type II inositol 1,4,5-trisphosphate 5-phosphatase; 3.1.3.36; 3.1.3.56; Phosphoinositide 5-phosphatase", "protein_names_refseq": "LOW QUALITY PROTEIN: type II inositol 1,4,5-trisphosphate 5-phosphatase", "tax_id": 10029, "disease": "", "pathway": " (cge:100751850)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613886.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Dec 18, 2018 this sequence version replaced XP_016830986.1. COMPLETENESS: full length., [RefSeq]; Regulates phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) cellular levels by cleaving the phosphate at the 5-position producing PtdIns(4)P. Also hydrolyzes the 5-position phosphate from inositol 1,4,5-trisphosphate (Ins(1,4,5)P3), thereby modulating cellular signaling events., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.86", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.86", "type": "external" }, { "id": "3.1.3.56", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.56", "type": "external" }, { "id": "3.1.3.36", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.36", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.95", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.95", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity;GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0030670 phagocytic vesicle membrane;GO:0031901 early endosome membrane;GO:0005793 endoplasmic reticulum-Golgi intermediate compartment", "go_biological_process": "GO:0007165 signal transduction;GO:0046856 phosphatidylinositol dephosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FCJ0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FCM0-1", "uniprot_id": [ { "id": "A0A9J7FCM0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FCM0", "type": "external" } ], "mass": 96523.0, "length": 877, "protein_name": "Molybdenum cofactor sulfurase", "gene_name": "LOC113834026", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: molybdenum cofactor sulfurase-like", "refseq_ac": [ { "id": "XP_027256390", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256390", "type": "external" } ], "gene_names_uniprotkb": "LOC113834026; MOCOS", "gene_names_refseq": "LOC113834026", "protein_names_uniprotkb": "Molybdenum cofactor sulfurase; 2.8.1.9; MCS; MOS; MoCo sulfurase; Molybdenum cofactor sulfurtransferase", "protein_names_refseq": "LOW QUALITY PROTEIN: molybdenum cofactor sulfurase-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113834026)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.8.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.1.9", "type": "external" } ], "go_molecular_function": "GO:0030151 molybdenum ion binding;GO:0030170 pyridoxal phosphate binding;GO:0016829 lyase activity;GO:0008265 molybdenum cofactor sulfurtransferase activity", "go_cellular_component": "", "go_biological_process": "GO:0006777 Mo-molybdopterin cofactor biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FCM0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FCP5-1", "uniprot_id": [ { "id": "A0A9J7FCP5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FCP5", "type": "external" } ], "mass": 35131.0, "length": 319, "protein_name": "KH domain-containing RNA-binding protein QKI", "gene_name": "Qki", "organism": "Hamster", "refseq_name": "protein quaking isoform X4", "refseq_ac": [ { "id": "XP_027256912", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256912", "type": "external" } ], "gene_names_uniprotkb": "Qki", "gene_names_refseq": "Qki", "protein_names_uniprotkb": "KH domain-containing RNA-binding protein QKI; Protein quaking", "protein_names_refseq": "protein quaking isoform X4", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0017124 SH3 domain binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006397 mRNA processing;GO:0006417 regulation of translation;GO:0030154 cell differentiation;GO:0048255 mRNA stabilization;GO:0048714 positive regulation of oligodendrocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FCP5-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FD49-1", "uniprot_id": [ { "id": "A0A9J7FD49_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FD49", "type": "external" } ], "mass": 78880.0, "length": 716, "protein_name": "Mannan-binding lectin serine protease 2", "gene_name": "LOC100770654", "organism": "Hamster", "refseq_name": "mannan-binding lectin serine protease 2 isoform X2", "refseq_ac": [ { "id": "XP_027254025", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254025", "type": "external" } ], "gene_names_uniprotkb": "LOC100770654", "gene_names_refseq": "LOC100770654", "protein_names_uniprotkb": "Mannan-binding lectin serine protease 2; 3.4.21.104; MBL-associated serine protease 2; Mannose-binding protein-associated serine protease 2", "protein_names_refseq": "mannan-binding lectin serine protease 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100770654)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 4% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027254025.1. COMPLETENESS: full length., [RefSeq]; Precursor of a serum protease that activates the lectin pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. The lectin complement system is activated following association of lectins, such as MBL2, FCN1, FCN2 or FCN3, to carbohydrates on the pathogen surface. MASP2 is cleaved and activated by MASP1 in response to lectin-binding to pathogen carbohydrates. Can activate prothrombin to thrombin., [UniProtKB, UniProtKB]; Serine protease component of the lectin complement pathway, which catalyzes cleavage and activation of C2 and C4, the next components of the complement pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006508 proteolysis;GO:0001867 complement activation, lectin pathway;GO:0006958 complement activation, classical pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FD49-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FD71-1", "uniprot_id": [ { "id": "A0A9J7FD71_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FD71", "type": "external" } ], "mass": 469261.0, "length": 4386, "protein_name": "Basement membrane-specific heparan sulfate proteoglycan core protein", "gene_name": "Hspg2", "organism": "Hamster", "refseq_name": "basement membrane-specific heparan sulfate proteoglycan core protein isoform X2", "refseq_ac": [ { "id": "XP_027255561", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255561", "type": "external" } ], "gene_names_uniprotkb": "Hspg2", "gene_names_refseq": "Hspg2", "protein_names_uniprotkb": "Basement membrane-specific heparan sulfate proteoglycan core protein; Perlecan", "protein_names_refseq": "basement membrane-specific heparan sulfate proteoglycan core protein isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100689041)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Anti-angiogenic and anti-tumor peptide that inhibits endothelial cell migration, collagen-induced endothelial tube morphogenesis and blood vessel growth in the chorioallantoic membrane. Blocks endothelial cell adhesion to fibronectin and type I collagen. Anti-tumor agent in neovascularization. Interaction with its ligand, integrin alpha2/beta1, is required for the anti-angiogenic properties. Evokes a reduction in phosphorylation of receptor tyrosine kinases via alpha2/beta1 integrin-mediated activation of the tyrosine phosphatase, PTPN6., [UniProtKB, UniProtKB]; Has anti-angiogenic properties that require binding of calcium ions for full activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0008046 axon guidance receptor activity", "go_cellular_component": "GO:0005796 Golgi lumen;GO:0005886 plasma membrane;GO:0030424 axon;GO:0043025 neuronal cell body;GO:0005604 basement membrane", "go_biological_process": "GO:0001525 angiogenesis;GO:0050808 synapse organization;GO:0007420 brain development;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FD71-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FD75-1", "uniprot_id": [ { "id": "A0A9J7FD75_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FD75", "type": "external" } ], "mass": 80799.0, "length": 718, "protein_name": "Interleukin-31 receptor subunit alpha", "gene_name": "Il31ra", "organism": "Hamster", "refseq_name": "interleukin-31 receptor subunit alpha isoform X1", "refseq_ac": [ { "id": "XP_007642228", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642228", "type": "external" } ], "gene_names_uniprotkb": "Il31ra", "gene_names_refseq": "Il31ra", "protein_names_uniprotkb": "Interleukin-31 receptor subunit alpha; GLM-R; Gp130-like monocyte receptor; ZcytoR17", "protein_names_refseq": "interleukin-31 receptor subunit alpha isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100770824)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613971.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1. Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019955 cytokine binding", "go_cellular_component": "GO:0042734 presynaptic membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0030154 cell differentiation;GO:0002376 immune system process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FD75-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FD79-1", "uniprot_id": [ { "id": "A0A9J7FD79_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FD79", "type": "external" } ], "mass": 180222.0, "length": 1598, "protein_name": "Mitogen-activated protein kinase kinase kinase 4", "gene_name": "Map3k4", "organism": "Hamster", "refseq_name": "mitogen-activated protein kinase kinase kinase 4 isoform X3", "refseq_ac": [ { "id": "XP_027256901", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256901", "type": "external" } ], "gene_names_uniprotkb": "Map3k4", "gene_names_refseq": "Map3k4", "protein_names_uniprotkb": "Mitogen-activated protein kinase kinase kinase 4; 2.7.11.25; MAPK/ERK kinase kinase 4", "protein_names_refseq": "mitogen-activated protein kinase kinase kinase 4 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100764060)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004709 MAP kinase kinase kinase activity", "go_cellular_component": "GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FD79-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FDD6-1", "uniprot_id": [ { "id": "A0A9J7FDD6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FDD6", "type": "external" } ], "mass": 96652.0, "length": 856, "protein_name": "DNA polymerase kappa", "gene_name": "Polk", "organism": "Hamster", "refseq_name": "DNA polymerase kappa isoform X3", "refseq_ac": [ { "id": "XP_027257484", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257484", "type": "external" } ], "gene_names_uniprotkb": "Polk", "gene_names_refseq": "Polk", "protein_names_uniprotkb": "DNA polymerase kappa; 2.7.7.7; DINB protein", "protein_names_refseq": "DNA polymerase kappa isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100758099)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Depending on the context, it inserts the correct base, but causes frequent base transitions, transversions and frameshifts. Lacks 3'-5' proofreading exonuclease activity. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.31", "type": "external" }, { "id": "2.7.7.102", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.102", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" } ], "go_molecular_function": "GO:0003887 DNA-directed DNA polymerase activity;GO:0008270 zinc ion binding;GO:0003684 damaged DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006281 DNA repair;GO:0042276 error-prone translesion synthesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FDD6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FDG0-1", "uniprot_id": [ { "id": "A0A9J7FDG0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FDG0", "type": "external" } ], "mass": 29932.0, "length": 269, "protein_name": "Mitochondrial ornithine transporter 1", "gene_name": "LOC100758204", "organism": "Hamster", "refseq_name": "mitochondrial ornithine transporter 2", "refseq_ac": [ { "id": "XP_027253780", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253780", "type": "external" } ], "gene_names_uniprotkb": "LOC100758204", "gene_names_refseq": "LOC100758204", "protein_names_uniprotkb": "Mitochondrial ornithine transporter 1; Solute carrier family 25 member 15", "protein_names_refseq": "mitochondrial ornithine transporter 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100758204)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Mitochondrial ornithine-citrulline antiporter. Catalyzes the exchange between cytosolic ornithine and mitochondrial citrulline plus an H(+), the proton compensates the positive charge of ornithine thus leading to an electroneutral transport. Plays a crucial role in the urea cycle, by connecting the cytosolic and the intramitochondrial reactions of the urea cycle. Lysine and arginine are also transported by the antiport mechanism. In addition, catalyzes an electroneutral exchange of ornithine or lysine for H(+), a reaction driven by the pH gradient across the inner membrane., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000064 L-ornithine transmembrane transporter activity;GO:0015297 antiporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:1990575 mitochondrial L-ornithine transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FDG0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FDR0-1", "uniprot_id": [ { "id": "A0A9J7FDR0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FDR0", "type": "external" } ], "mass": 62514.0, "length": 546, "protein_name": "Arylsulfatase K", "gene_name": "Arsk", "organism": "Hamster", "refseq_name": "arylsulfatase K isoform X1", "refseq_ac": [ { "id": "XP_007638935", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638935", "type": "external" } ], "gene_names_uniprotkb": "Arsk", "gene_names_refseq": "Arsk", "protein_names_uniprotkb": "Arylsulfatase K; 3.1.6.18; 3.1.6.1; Glucuronate-2-sulfatase", "protein_names_refseq": "arylsulfatase K isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100762898)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 1037 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613767.1) and transcript sequence (IACG01004521.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the hydrolysis of pseudosubstrates such as p-nitrocatechol sulfate and p-nitrophenyl sulfate. Catalyzes the hydrolysis of the 2-sulfate groups of the 2-O-sulfo-D-glucuronate residues of chondroitin sulfate, heparin and heparitin sulfate. Acts selectively on 2-sulfoglucuronate and lacks activity against 2-sulfoiduronate., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.6.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.6.1", "type": "external" }, { "id": "3.1.6.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.6.15", "type": "external" }, { "id": "3.1.6.18", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.6.18", "type": "external" }, { "id": "3.1.6.14", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.6.14", "type": "external" }, { "id": "3.1.6.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.6.-", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004065 arylsulfatase activity;GO:0015024 glucuronate-2-sulfatase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005764 lysosome", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FDR0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FDT4-1", "uniprot_id": [ { "id": "A0A9J7FDT4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FDT4", "type": "external" } ], "mass": 38057.0, "length": 343, "protein_name": "Draxin", "gene_name": "LOC100766781", "organism": "Hamster", "refseq_name": "draxin isoform X2", "refseq_ac": [ { "id": "XP_027253996", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253996", "type": "external" } ], "gene_names_uniprotkb": "LOC100766781; DRAXIN", "gene_names_refseq": "LOC100766781", "protein_names_uniprotkb": "Draxin; Dorsal inhibitory axon guidance protein; Dorsal repulsive axon guidance protein", "protein_names_refseq": "draxin isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100766781)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0021516 dorsal spinal cord development;GO:0030900 forebrain development;GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0016055 Wnt signaling pathway;GO:0007411 axon guidance", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FDT4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FIX8-1", "uniprot_id": [ { "id": "A0A9J7FIX8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FIX8", "type": "external" } ], "mass": 138990.0, "length": 1248, "protein_name": "Adhesion G-protein coupled receptor G6", "gene_name": "Adgrg6", "organism": "Hamster", "refseq_name": "adhesion G-protein coupled receptor G6 isoform X1", "refseq_ac": [ { "id": "XP_007640059", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640059", "type": "external" } ], "gene_names_uniprotkb": "Adgrg6", "gene_names_refseq": "Adgrg6", "protein_names_uniprotkb": "Adhesion G-protein coupled receptor G6; Developmentally regulated G-protein-coupled receptor; G-protein coupled receptor 126", "protein_names_refseq": "adhesion G-protein coupled receptor G6 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100772057)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613836.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Adhesion G-protein coupled receptor (aGPCR) for steroid hormones, such as progesterone and 17alpha-hydroxyprogesterone (17OHP). Involved in many biological processes, such as myelination, sprouting angiogenesis, placenta, ear and cartilage development. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. ADGRG6 is coupled to G(i) G alpha proteins and mediates inhibition of adenylate cyclase. Also able to couple to G(q) G proteins. Involved in myelination of the peripheral nervous system: required for differentiation of promyelinating Schwann cells and for normal myelination of axons. Also acts as a regulator of body length and bone mass. Acts as a regulator of blood-brain barrier formation in the central nervous system vie its association with LRP1 and ITGB1., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0046872 metal ion binding;GO:0043236 laminin binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005737 cytoplasm;GO:0009986 cell surface", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0022011 myelination in peripheral nervous system;GO:0060347 heart trabecula formation;GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FIX8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FHM4-1", "uniprot_id": [ { "id": "A0A9J7FHM4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FHM4", "type": "external" } ], "mass": 127660.0, "length": 1152, "protein_name": "Syntaxin-binding protein 5", "gene_name": "Stxbp5", "organism": "Hamster", "refseq_name": "syntaxin-binding protein 5 isoform X1", "refseq_ac": [ { "id": "XP_027257834", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257834", "type": "external" } ], "gene_names_uniprotkb": "Stxbp5", "gene_names_refseq": "Stxbp5", "protein_names_uniprotkb": "Syntaxin-binding protein 5; Lethal(2) giant larvae protein homolog 3; Tomosyn-1", "protein_names_refseq": "syntaxin-binding protein 5 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100761348)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0045159 myosin II binding;GO:0005096 GTPase activator activity;GO:0017075 syntaxin-1 binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030141 secretory granule;GO:0019898 extrinsic component of membrane;GO:0031201 SNARE complex", "go_biological_process": "GO:0015031 protein transport;GO:0006887 exocytosis;GO:0006893 Golgi to plasma membrane transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FHM4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FE85-1", "uniprot_id": [ { "id": "A0A9J7FE85_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FE85", "type": "external" } ], "mass": 57190.0, "length": 524, "protein_name": "Succinyl-CoA:3-ketoacid-coenzyme A transferase", "gene_name": "LOC113833845", "organism": "Hamster", "refseq_name": "succinyl-CoA:3-ketoacid coenzyme A transferase 2A, mitochondrial-like", "refseq_ac": [ { "id": "XP_027254979", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254979", "type": "external" } ], "gene_names_uniprotkb": "LOC113833845", "gene_names_refseq": "LOC113833845", "protein_names_uniprotkb": "Succinyl-CoA:3-ketoacid-coenzyme A transferase; 2.8.3.5", "protein_names_refseq": "succinyl-CoA:3-ketoacid coenzyme A transferase 2A, mitochondrial-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113833845)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.8.3.5", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.3.5", "type": "external" } ], "go_molecular_function": "GO:0008260 succinyl-CoA:3-oxo-acid CoA-transferase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0046952 ketone body catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FE85-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FG35-1", "uniprot_id": [ { "id": "A0A9J7FG35_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FG35", "type": "external" } ], "mass": 48875.0, "length": 424, "protein_name": "m7GpppN-mRNA hydrolase", "gene_name": "Dcp2", "organism": "Hamster", "refseq_name": "m7GpppN-mRNA hydrolase isoform X2", "refseq_ac": [ { "id": "XP_027256647", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256647", "type": "external" } ], "gene_names_uniprotkb": "Dcp2", "gene_names_refseq": "Dcp2", "protein_names_uniprotkb": "m7GpppN-mRNA hydrolase; 3.6.1.62; mRNA-decapping enzyme 2", "protein_names_refseq": "m7GpppN-mRNA hydrolase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100773631)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Decapping metalloenzyme that catalyzes the cleavage of the cap structure on mRNAs. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Plays a role in replication-dependent histone mRNA degradation. Has higher activity towards mRNAs that lack a poly(A) tail. Has no activity towards a cap structure lacking an RNA moiety. The presence of a N(6)-methyladenosine methylation at the second transcribed position of mRNAs (N(6),2'-O-dimethyladenosine cap; m6A(m)) provides resistance to DCP2-mediated decapping. Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degradation of their transcripts., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.1.62", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.62", "type": "external" }, { "id": "3.6.1.64", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.64", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0030145 manganese ion binding;GO:0140933 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000932 P-body", "go_biological_process": "GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FG35-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FG54-1", "uniprot_id": [ { "id": "A0A9J7FG54_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FG54", "type": "external" } ], "mass": 58487.0, "length": 519, "protein_name": "Sorting nexin-2", "gene_name": "Snx2", "organism": "Hamster", "refseq_name": "sorting nexin-2 isoform X1", "refseq_ac": [ { "id": "XP_007642843", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642843", "type": "external" } ], "gene_names_uniprotkb": "Snx2", "gene_names_refseq": "Snx2", "protein_names_uniprotkb": "Sorting nexin-2", "protein_names_refseq": "sorting nexin-2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100774009)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 198 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614035.1) and transcript sequence (IACG01092346.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007642843.2. COMPLETENESS: full length., [RefSeq]; Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC). Can sense membrane curvature and has in vitro vesicle-to-membrane remodeling activity. Required for retrograde endosome-to-TGN transport of TGN38. Promotes KALRN- and RHOG-dependent but retromer-independent membrane remodeling such as lamellipodium formation; the function is dependent on GEF activity of KALRN., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0035091 phosphatidylinositol binding", "go_cellular_component": "GO:0005829 cytosol;GO:0030027 lamellipodium;GO:0031901 early endosome membrane;GO:0030904 retromer complex", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0034498 early endosome to Golgi transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FG54-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FFN4-1", "uniprot_id": [ { "id": "A0A9J7FFN4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FFN4", "type": "external" } ], "mass": 29860.0, "length": 261, "protein_name": "Androgen-induced gene 1 protein isoform X3", "gene_name": "Aig1", "organism": "Hamster", "refseq_name": "androgen-induced gene 1 protein isoform X3", "refseq_ac": [ { "id": "XP_027257788", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257788", "type": "external" } ], "gene_names_uniprotkb": "Aig1", "gene_names_refseq": "Aig1", "protein_names_uniprotkb": "Androgen-induced gene 1 protein isoform X3", "protein_names_refseq": "androgen-induced gene 1 protein isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100757869)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.-", "type": "external" } ], "go_molecular_function": "GO:0016787 hydrolase activity", "go_cellular_component": "GO:0016020 membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0042758 long-chain fatty acid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FFN4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FEG8-1", "uniprot_id": [ { "id": "A0A9J7FEG8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FEG8", "type": "external" } ], "mass": 313572.0, "length": 2906, "protein_name": "Fibrillin-2", "gene_name": "Fbn2", "organism": "Hamster", "refseq_name": "fibrillin-2 isoform X2", "refseq_ac": [ { "id": "XP_027256739", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256739", "type": "external" } ], "gene_names_uniprotkb": "Fbn2", "gene_names_refseq": "Fbn2", "protein_names_uniprotkb": "Fibrillin-2", "protein_names_refseq": "fibrillin-2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100769316)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-2-containing microfibrils regulate the early process of elastic fiber assembly. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively., [UniProtKB, UniProtKB, UniProtKB]; Hormone secreted by trophoblasts that promotes trophoblast invasiveness. Has glucogenic activity: is able to increase plasma glucose levels., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0005179 hormone activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0001527 microfibril", "go_biological_process": "GO:0048731 system development;GO:0035583 sequestering of TGFbeta in extracellular matrix;GO:0009887 animal organ morphogenesis;GO:0048598 embryonic morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FEG8-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FEH4-1", "uniprot_id": [ { "id": "A0A9J7FEH4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FEH4", "type": "external" } ], "mass": 102595.0, "length": 934, "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "Eps15", "organism": "Hamster", "refseq_name": "epidermal growth factor receptor substrate 15 isoform X2", "refseq_ac": [ { "id": "XP_027258248", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258248", "type": "external" } ], "gene_names_uniprotkb": "Eps15", "gene_names_refseq": "Eps15", "protein_names_uniprotkb": "Epidermal growth factor receptor substrate 15; Protein AF-1p", "protein_names_refseq": "epidermal growth factor receptor substrate 15 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100751122)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in cell growth regulation. May be involved in the regulation of mitogenic signals and control of cell proliferation. Involved in the internalization of ligand-inducible receptors of the receptor tyrosine kinase (RTK) type, in particular EGFR. Plays a role in the assembly of clathrin-coated pits (CCPs). Acts as a clathrin adapter required for post-Golgi trafficking. Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017124 SH3 domain binding;GO:0005509 calcium ion binding;GO:0045296 cadherin binding;GO:0031593 polyubiquitin modification-dependent protein binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0031901 early endosome membrane;GO:0030132 clathrin coat of coated pit;GO:0005829 cytosol;GO:0030122 AP-2 adaptor complex;GO:0060170 ciliary membrane", "go_biological_process": "GO:0006897 endocytosis;GO:0015031 protein transport;GO:0016197 endosomal transport;GO:0048268 clathrin coat assembly;GO:0006895 Golgi to endosome transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FEH4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FEK6-1", "uniprot_id": [ { "id": "A0A9J7FEK6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FEK6", "type": "external" } ], "mass": 38544.0, "length": 357, "protein_name": "Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase", "gene_name": "Bpnt2", "organism": "Hamster", "refseq_name": "Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase isoform X1", "refseq_ac": [ { "id": "XP_007640788", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640788", "type": "external" } ], "gene_names_uniprotkb": "Bpnt2", "gene_names_refseq": "Bpnt2", "protein_names_uniprotkb": "Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase; 3'(2'), 5'-bisphosphate nucleotidase 2; 3.1.3.7; Inositol monophosphatase domain-containing protein 1; Myo-inositol monophosphatase A3; Phosphoadenosine phosphate 3'-nucleotidase", "protein_names_refseq": "Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100756245)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 515 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613868.1) and transcript sequence (IACG01077159.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007640788.1. COMPLETENESS: full length., [RefSeq]; Exhibits 3'-nucleotidase activity toward adenosine 3',5'-bisphosphate (PAP), namely hydrolyzes adenosine 3',5'-bisphosphate into adenosine 5'-monophosphate (AMP) and a phosphate. May play a role in the formation of skeletal elements derived through endochondral ossification, possibly by clearing adenosine 3',5'-bisphosphate produced by Golgi sulfotransferases during glycosaminoglycan sulfation. Has no activity toward 3'-phosphoadenosine 5'-phosphosulfate (PAPS) or inositol phosphate (IP) substrates including I(1)P, I(1,4)P2, I(1,3,4)P3, I(1,4,5)P3 and I(1,3,4,5)P4., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.57", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.57", "type": "external" }, { "id": "3.1.3.7", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.7", "type": "external" } ], "go_molecular_function": "GO:0008254 3'-nucleotidase activity;GO:0046872 metal ion binding;GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity", "go_cellular_component": "GO:0005794 Golgi apparatus", "go_biological_process": "GO:0001501 skeletal system development;GO:0046854 phosphatidylinositol phosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FEK6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FEU6-1", "uniprot_id": [ { "id": "A0A9J7FEU6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FEU6", "type": "external" } ], "mass": 21106.0, "length": 191, "protein_name": "Peptidyl-prolyl cis-trans isomerase", "gene_name": "Ppih", "organism": "Hamster", "refseq_name": "peptidyl-prolyl cis-trans isomerase H isoform X2", "refseq_ac": [ { "id": "XP_016818585", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016818585", "type": "external" } ], "gene_names_uniprotkb": "Ppih", "gene_names_refseq": "Ppih", "protein_names_uniprotkb": "Peptidyl-prolyl cis-trans isomerase; 5.2.1.8; PPIase", "protein_names_refseq": "peptidyl-prolyl cis-trans isomerase H isoform X2", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615864.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. Participates in pre-mRNA splicing. May play a role in the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. May act as a chaperone., [UniProtKB, UniProtKB]; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0016018 cyclosporin A binding;GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016607 nuclear speck;GO:0005681 spliceosomal complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0008380 RNA splicing;GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FEU6-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FEZ2-1", "uniprot_id": [ { "id": "A0A9J7FEZ2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FEZ2", "type": "external" } ], "mass": 107440.0, "length": 963, "protein_name": "Ephrin type-B receptor 1", "gene_name": "Ephb2", "organism": "Hamster", "refseq_name": "ephrin type-B receptor 2", "refseq_ac": [ { "id": "XP_003503686", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503686", "type": "external" } ], "gene_names_uniprotkb": "Ephb2", "gene_names_refseq": "Ephb2", "protein_names_uniprotkb": "Ephrin type-B receptor 1; 2.7.10.1", "protein_names_refseq": "ephrin type-B receptor 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100766993)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613985.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0005005 transmembrane-ephrin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030425 dendrite", "go_biological_process": "GO:0016477 cell migration;GO:0007417 central nervous system development;GO:0060996 dendritic spine development;GO:0007411 axon guidance;GO:0048513 animal organ development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FEZ2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FEZ5-1", "uniprot_id": [ { "id": "A0A9J7FEZ5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FEZ5", "type": "external" } ], "mass": 47537.0, "length": 406, "protein_name": "Tyrosine-protein phosphatase non-receptor type", "gene_name": "Ptpn2", "organism": "Hamster", "refseq_name": "tyrosine-protein phosphatase non-receptor type 2 isoform X2", "refseq_ac": [ { "id": "XP_027258488", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258488", "type": "external" } ], "gene_names_uniprotkb": "Ptpn2", "gene_names_refseq": "Ptpn2", "protein_names_uniprotkb": "Tyrosine-protein phosphatase non-receptor type; 3.1.3.48", "protein_names_refseq": "tyrosine-protein phosphatase non-receptor type 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:103163089)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" } ], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0004726 non-membrane spanning protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0070373 negative regulation of ERK1 and ERK2 cascade;GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FEZ5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FF26-1", "uniprot_id": [ { "id": "A0A9J7FF26_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FF26", "type": "external" } ], "mass": 110113.0, "length": 956, "protein_name": "E3 ubiquitin-protein ligase NEDD4-like", "gene_name": "Nedd4l", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase NEDD4-like isoform X2", "refseq_ac": [ { "id": "XP_027258552", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258552", "type": "external" } ], "gene_names_uniprotkb": "Nedd4l", "gene_names_refseq": "Nedd4l", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase NEDD4-like; 2.3.2.26; HECT-type E3 ubiquitin transferase NED4L", "protein_names_refseq": "E3 ubiquitin-protein ligase NEDD4-like isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100769118)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019871 sodium channel inhibitor activity;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005771 multivesicular body", "go_biological_process": "GO:0006811 monoatomic ion transport;GO:0030154 cell differentiation;GO:0048814 regulation of dendrite morphogenesis;GO:0016567 protein ubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FF26-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FF66-1", "uniprot_id": [ { "id": "A0A9J7FF66_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FF66", "type": "external" } ], "mass": 45750.0, "length": 404, "protein_name": "5-hydroxytryptamine receptor 4", "gene_name": "Htr4", "organism": "Hamster", "refseq_name": "5-hydroxytryptamine receptor 4 isoform X2", "refseq_ac": [ { "id": "XP_027258650", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258650", "type": "external" } ], "gene_names_uniprotkb": "Htr4", "gene_names_refseq": "Htr4", "protein_names_uniprotkb": "5-hydroxytryptamine receptor 4; Serotonin receptor 4", "protein_names_refseq": "5-hydroxytryptamine receptor 4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763863)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 6% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; G-protein coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR4 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004993 G protein-coupled serotonin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045202 synapse;GO:0010008 endosome membrane", "go_biological_process": "GO:0043410 positive regulation of MAPK cascade;GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0007268 chemical synaptic transmission;GO:0032098 regulation of appetite;GO:0003008 system process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FF66-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FFM3-1", "uniprot_id": [ { "id": "A0A9J7FFM3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FFM3", "type": "external" } ], "mass": 37592.0, "length": 351, "protein_name": "Arginase", "gene_name": "Arg1", "organism": "Hamster", "refseq_name": "arginase-1 isoform X1", "refseq_ac": [ { "id": "XP_003513140", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513140", "type": "external" } ], "gene_names_uniprotkb": "Arg1", "gene_names_refseq": "Arg1", "protein_names_uniprotkb": "Arginase; 3.5.3.1", "protein_names_refseq": "arginase-1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100750727)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615724.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Dec 18, 2018 this sequence version replaced XP_003513140.1. COMPLETENESS: full length., [RefSeq]; Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell proliferation, respectively; the urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.5.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.3.1", "type": "external" }, { "id": "3.5.3.17", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.3.17", "type": "external" }, { "id": "3.5.3.7", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.3.7", "type": "external" } ], "go_molecular_function": "GO:0030145 manganese ion binding;GO:0004053 arginase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0042127 regulation of cell population proliferation;GO:0000050 urea cycle;GO:0006525 arginine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FFM3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FKM1-1", "uniprot_id": [ { "id": "A0A9J7FKM1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FKM1", "type": "external" } ], "mass": 73120.0, "length": 642, "protein_name": "Maternal embryonic leucine zipper kinase", "gene_name": "Melk", "organism": "Hamster", "refseq_name": "maternal embryonic leucine zipper kinase isoform X1", "refseq_ac": [ { "id": "XP_027258998", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258998", "type": "external" } ], "gene_names_uniprotkb": "Melk", "gene_names_refseq": "Melk", "protein_names_uniprotkb": "Maternal embryonic leucine zipper kinase; 2.7.10.2; 2.7.11.1; Protein kinase PK38; Tyrosine-protein kinase MELK", "protein_names_refseq": "maternal embryonic leucine zipper kinase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100774970)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0008289 lipid binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0008283 cell population proliferation;GO:0035556 intracellular signal transduction;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FKM1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FFQ1-1", "uniprot_id": [ { "id": "A0A9J7FFQ1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FFQ1", "type": "external" } ], "mass": 53169.0, "length": 460, "protein_name": "Angiopoietin-related protein 3", "gene_name": "Angptl3", "organism": "Hamster", "refseq_name": "angiopoietin-related protein 3", "refseq_ac": [ { "id": "XP_003497649", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497649", "type": "external" } ], "gene_names_uniprotkb": "Angptl3", "gene_names_refseq": "Angptl3", "protein_names_uniprotkb": "Angiopoietin-related protein 3; Angiopoietin-like protein 3", "protein_names_refseq": "angiopoietin-related protein 3", "tax_id": 10029, "disease": "", "pathway": " (cge:100754950)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613655.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008201 heparin binding;GO:0030674 protein-macromolecule adaptor activity;GO:0004859 phospholipase inhibitor activity;GO:0005201 extracellular matrix structural constituent", "go_cellular_component": "GO:0009986 cell surface;GO:0030027 lamellipodium;GO:0005577 fibrinogen complex", "go_biological_process": "GO:0001525 angiogenesis;GO:0006629 lipid metabolic process;GO:0042632 cholesterol homeostasis;GO:0042730 fibrinolysis;GO:0055091 phospholipid homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FFQ1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FFQ5-1", "uniprot_id": [ { "id": "A0A9J7FFQ5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FFQ5", "type": "external" } ], "mass": 86581.0, "length": 749, "protein_name": "Cyclic nucleotide-gated cation channel beta-3 isoform X2", "gene_name": "Cngb3", "organism": "Hamster", "refseq_name": "cyclic nucleotide-gated cation channel beta-3 isoform X2", "refseq_ac": [ { "id": "XP_027258773", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258773", "type": "external" } ], "gene_names_uniprotkb": "Cngb3", "gene_names_refseq": "Cngb3", "protein_names_uniprotkb": "Cyclic nucleotide-gated cation channel beta-3 isoform X2", "protein_names_refseq": "cyclic nucleotide-gated cation channel beta-3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100757356)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 7% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0044877 protein-containing complex binding;GO:0005223 intracellularly cGMP-activated cation channel activity;GO:0005222 intracellularly cAMP-activated cation channel activity;GO:0030553 cGMP binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0001750 photoreceptor outer segment;GO:0017071 intracellular cyclic nucleotide activated cation channel complex", "go_biological_process": "GO:0007601 visual perception", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FFQ5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FG72-1", "uniprot_id": [ { "id": "A0A9J7FG72_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FG72", "type": "external" } ], "mass": 90994.0, "length": 843, "protein_name": "Pro-neuregulin-2, membrane-bound isoform", "gene_name": "Nrg2", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: pro-neuregulin-2, membrane-bound isoform isoform X2", "refseq_ac": [ { "id": "XP_027256577", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256577", "type": "external" } ], "gene_names_uniprotkb": "Nrg2", "gene_names_refseq": "Nrg2", "protein_names_uniprotkb": "Pro-neuregulin-2, membrane-bound isoform", "protein_names_refseq": "LOW QUALITY PROTEIN: pro-neuregulin-2, membrane-bound isoform isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100759245)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. May also promote the heterodimerization with the EGF receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008083 growth factor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane", "go_biological_process": "GO:0007399 nervous system development;GO:0035556 intracellular signal transduction;GO:0048513 animal organ development;GO:0038130 ERBB4 signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FG72-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FGV0-1", "uniprot_id": [ { "id": "A0A9J7FGV0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FGV0", "type": "external" } ], "mass": 57161.0, "length": 499, "protein_name": "steroid 11beta-monooxygenase", "gene_name": "LOC100771648", "organism": "Hamster", "refseq_name": "cytochrome P450 11B1, mitochondrial isoform X1", "refseq_ac": [ { "id": "XP_003515182", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003515182", "type": "external" } ], "gene_names_uniprotkb": "LOC100771648", "gene_names_refseq": "LOC100771648", "protein_names_uniprotkb": "steroid 11beta-monooxygenase; 1.14.15.4", "protein_names_refseq": "cytochrome P450 11B1, mitochondrial isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100771648)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 130 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003617401.1) and transcript sequence (IACG01045365.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.15.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.15.4", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004507 steroid 11-beta-monooxygenase activity;GO:0047783 corticosterone 18-monooxygenase activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0008203 cholesterol metabolic process;GO:0006704 glucocorticoid biosynthetic process;GO:0071375 cellular response to peptide hormone stimulus;GO:0032342 aldosterone biosynthetic process;GO:0034650 cortisol metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FGV0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FK66-1", "uniprot_id": [ { "id": "A0A9J7FK66_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FK66", "type": "external" } ], "mass": 57804.0, "length": 536, "protein_name": "Nicotinate phosphoribosyltransferase", "gene_name": "Naprt", "organism": "Hamster", "refseq_name": "nicotinate phosphoribosyltransferase isoform X1", "refseq_ac": [ { "id": "XP_027259675", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259675", "type": "external" } ], "gene_names_uniprotkb": "Naprt", "gene_names_refseq": "Naprt", "protein_names_uniprotkb": "Nicotinate phosphoribosyltransferase; 6.3.4.21", "protein_names_refseq": "nicotinate phosphoribosyltransferase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100756372)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Helps prevent cellular oxidative stress via its role in NAD biosynthesis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.3.4.21", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.4.21", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0016757 glycosyltransferase activity;GO:0004516 nicotinate phosphoribosyltransferase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0034355 NAD+ biosynthetic process via the salvage pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FK66-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FGD2-1", "uniprot_id": [ { "id": "A0A9J7FGD2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FGD2", "type": "external" } ], "mass": 168591.0, "length": 1523, "protein_name": "Synaptojanin-2", "gene_name": "Synj2", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: synaptojanin-2 isoform X2", "refseq_ac": [ { "id": "XP_027256867", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256867", "type": "external" } ], "gene_names_uniprotkb": "Synj2", "gene_names_refseq": "Synj2", "protein_names_uniprotkb": "Synaptojanin-2; 3.1.3.36; Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2", "protein_names_refseq": "LOW QUALITY PROTEIN: synaptojanin-2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774472)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Inositol 5-phosphatase which may be involved in distinct membrane trafficking and signal transduction pathways. May mediate the inhibitory effect of Rac1 on endocytosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.86", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.86", "type": "external" }, { "id": "3.1.3.56", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.56", "type": "external" }, { "id": "3.1.3.36", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.36", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.95", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.95", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0017124 SH3 domain binding;GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0045121 membrane raft;GO:0048471 perinuclear region of cytoplasm;GO:0098793 presynapse", "go_biological_process": "GO:0046856 phosphatidylinositol dephosphorylation;GO:0048488 synaptic vesicle endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FGD2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FGE1-1", "uniprot_id": [ { "id": "A0A9J7FGE1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FGE1", "type": "external" } ], "mass": 46469.0, "length": 410, "protein_name": "Lysyl oxidase homolog", "gene_name": "LOC100764517", "organism": "Hamster", "refseq_name": "protein-lysine 6-oxidase isoform X2", "refseq_ac": [ { "id": "XP_027256689", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256689", "type": "external" } ], "gene_names_uniprotkb": "LOC100764517", "gene_names_refseq": "LOC100764517", "protein_names_uniprotkb": "Lysyl oxidase homolog; 1.4.3.13", "protein_names_refseq": "protein-lysine 6-oxidase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100764517)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine)., [UniProtKB, UniProtKB]; Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Regulator of Ras expression. May play a role in tumor suppression. Plays a role in the aortic wall architecture., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.4.3.13", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.13", "type": "external" } ], "go_molecular_function": "GO:0005507 copper ion binding;GO:0004720 protein-lysine 6-oxidase activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0030199 collagen fibril organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FGE1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FLH1-1", "uniprot_id": [ { "id": "A0A9J7FLH1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FLH1", "type": "external" } ], "mass": 73158.0, "length": 627, "protein_name": "DNA topoisomerase I", "gene_name": "Top1mt", "organism": "Hamster", "refseq_name": "DNA topoisomerase I, mitochondrial isoform X3", "refseq_ac": [ { "id": "XP_027259666", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259666", "type": "external" } ], "gene_names_uniprotkb": "Top1mt", "gene_names_refseq": "Top1mt", "protein_names_uniprotkb": "DNA topoisomerase I; 5.6.2.1; DNA topoisomerase 1", "protein_names_refseq": "DNA topoisomerase I, mitochondrial isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100759175)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003917 DNA topoisomerase type I (single strand cut, ATP-independent) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0042645 mitochondrial nucleoid;GO:0005694 chromosome", "go_biological_process": "GO:0006260 DNA replication;GO:0006265 DNA topological change", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FLH1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FIJ2-1", "uniprot_id": [ { "id": "A0A9J7FIJ2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FIJ2", "type": "external" } ], "mass": 46352.0, "length": 420, "protein_name": "Nucleoporin SEH1", "gene_name": "Seh1l", "organism": "Hamster", "refseq_name": "nucleoporin SEH1 isoform X2", "refseq_ac": [ { "id": "XP_027258485", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258485", "type": "external" } ], "gene_names_uniprotkb": "Seh1l", "gene_names_refseq": "Seh1l", "protein_names_uniprotkb": "Nucleoporin SEH1; GATOR2 complex protein SEH1; Nucleoporin seh1; Nup107-160 subcomplex subunit SEH1", "protein_names_refseq": "nucleoporin SEH1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100757132)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; As a component of the GATOR2 complex, functions as an activator of the amino acid-sensing branch of the mTORC1 signaling pathway. The GATOR2 complex indirectly activates mTORC1 through the inhibition of the GATOR1 subcomplex. GATOR2 probably acts as an E3 ubiquitin-protein ligase toward GATOR1. In the presence of abundant amino acids, the GATOR2 complex mediates ubiquitination of the NPRL2 core component of the GATOR1 complex, leading to GATOR1 inactivation. In the absence of amino acids, GATOR2 is inhibited, activating the GATOR1 complex. Within the GATOR2 complex, SEC13 and SEH1L are required to stabilize the complex., [UniProtKB, UniProtKB, UniProtKB]; Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0031080 nuclear pore outer ring;GO:0005765 lysosomal membrane;GO:0000776 kinetochore;GO:0035859 Seh1-associated complex", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0007059 chromosome segregation;GO:0015031 protein transport;GO:0051301 cell division;GO:0034198 cellular response to amino acid starvation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FIJ2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FGQ0-1", "uniprot_id": [ { "id": "A0A9J7FGQ0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FGQ0", "type": "external" } ], "mass": 128020.0, "length": 1136, "protein_name": "Phospholipid-transporting ATPase", "gene_name": "Atp9b", "organism": "Hamster", "refseq_name": "probable phospholipid-transporting ATPase IIB isoform X4", "refseq_ac": [ { "id": "XP_027259482", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259482", "type": "external" } ], "gene_names_uniprotkb": "Atp9b", "gene_names_refseq": "Atp9b", "protein_names_uniprotkb": "Phospholipid-transporting ATPase; 7.6.2.1", "protein_names_refseq": "probable phospholipid-transporting ATPase IIB isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100765138)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0140326 ATPase-coupled intramembrane lipid transporter activity", "go_cellular_component": "GO:0005768 endosome;GO:0005886 plasma membrane;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0006897 endocytosis;GO:0045332 phospholipid translocation;GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FGQ0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FI54-1", "uniprot_id": [ { "id": "A0A9J7FI54_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FI54", "type": "external" } ], "mass": 75383.0, "length": 692, "protein_name": "SH3 domain-binding protein 1", "gene_name": "Sh3bp1", "organism": "Hamster", "refseq_name": "SH3 domain-binding protein 1 isoform X2", "refseq_ac": [ { "id": "XP_027259767", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259767", "type": "external" } ], "gene_names_uniprotkb": "Sh3bp1", "gene_names_refseq": "Sh3bp1", "protein_names_uniprotkb": "SH3 domain-binding protein 1", "protein_names_refseq": "SH3 domain-binding protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100751677)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0017124 SH3 domain binding", "go_cellular_component": "GO:0005829 cytosol;GO:0001891 phagocytic cup;GO:0005912 adherens junction;GO:0005923 bicellular tight junction", "go_biological_process": "GO:0007165 signal transduction;GO:0032956 regulation of actin cytoskeleton organization;GO:0035020 regulation of Rac protein signal transduction;GO:0006909 phagocytosis;GO:0120031 plasma membrane bounded cell projection assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FI54-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FGR0-1", "uniprot_id": [ { "id": "A0A9J7FGR0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FGR0", "type": "external" } ], "mass": 179787.0, "length": 1663, "protein_name": "Protein scribble homolog", "gene_name": "Scrib", "organism": "Hamster", "refseq_name": "protein scribble homolog isoform X7", "refseq_ac": [ { "id": "XP_027259959", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259959", "type": "external" } ], "gene_names_uniprotkb": "Scrib", "gene_names_refseq": "Scrib", "protein_names_uniprotkb": "Protein scribble homolog; Protein LAP4", "protein_names_refseq": "protein scribble homolog isoform X7", "tax_id": 10029, "disease": "", "pathway": " (cge:100758586)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005912 adherens junction;GO:0014069 postsynaptic density;GO:0016323 basolateral plasma membrane;GO:0030027 lamellipodium", "go_biological_process": "GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane;GO:0030154 cell differentiation;GO:0098609 cell-cell adhesion;GO:0001843 neural tube closure;GO:0043113 receptor clustering", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FGR0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FGU7-1", "uniprot_id": [ { "id": "A0A9J7FGU7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FGU7", "type": "external" } ], "mass": 243267.0, "length": 2202, "protein_name": "Voltage-dependent T-type calcium channel subunit alpha", "gene_name": "LOC100769169", "organism": "Hamster", "refseq_name": "voltage-dependent T-type calcium channel subunit alpha-1I isoform X4", "refseq_ac": [ { "id": "XP_027259846", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259846", "type": "external" } ], "gene_names_uniprotkb": "LOC100769169", "gene_names_refseq": "LOC100769169", "protein_names_uniprotkb": "Voltage-dependent T-type calcium channel subunit alpha", "protein_names_refseq": "voltage-dependent T-type calcium channel subunit alpha-1I isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100769169)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the `low-voltage activated (LVA)` group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0008331 high voltage-gated calcium channel activity", "go_cellular_component": "GO:0005891 voltage-gated calcium channel complex", "go_biological_process": "GO:0098703 calcium ion import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FGU7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FGV4-1", "uniprot_id": [ { "id": "A0A9J7FGV4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FGV4", "type": "external" } ], "mass": 176157.0, "length": 1583, "protein_name": "A disintegrin and metalloproteinase with thrombospondin motifs 12", "gene_name": "Adamts12", "organism": "Hamster", "refseq_name": "A disintegrin and metalloproteinase with thrombospondin motifs 12", "refseq_ac": [ { "id": "XP_027257067", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257067", "type": "external" } ], "gene_names_uniprotkb": "Adamts12", "gene_names_refseq": "Adamts12", "protein_names_uniprotkb": "A disintegrin and metalloproteinase with thrombospondin motifs 12", "protein_names_refseq": "A disintegrin and metalloproteinase with thrombospondin motifs 12", "tax_id": 10029, "disease": "", "pathway": " (cge:100772449)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0031012 extracellular matrix", "go_biological_process": "GO:0043931 ossification involved in bone maturation;GO:0006508 proteolysis;GO:0030199 collagen fibril organization;GO:0002062 chondrocyte differentiation;GO:0006029 proteoglycan metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FGV4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FGZ7-1", "uniprot_id": [ { "id": "A0A9J7FGZ7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FGZ7", "type": "external" } ], "mass": 131289.0, "length": 1179, "protein_name": "Integrin alpha-1", "gene_name": "Itga1", "organism": "Hamster", "refseq_name": "integrin alpha-1", "refseq_ac": [ { "id": "XP_027257226", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257226", "type": "external" } ], "gene_names_uniprotkb": "Itga1", "gene_names_refseq": "Itga1", "protein_names_uniprotkb": "Integrin alpha-1; CD49 antigen-like family member A; Laminin and collagen receptor; VLA-1", "protein_names_refseq": "integrin alpha-1", "tax_id": 10029, "disease": "", "pathway": " (cge:100750393)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Involved in anchorage-dependent, negative regulation of EGF-stimulated cell growth., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0009897 external side of plasma membrane;GO:0008305 integrin complex", "go_biological_process": "GO:0007229 integrin-mediated signaling pathway;GO:0007160 cell-matrix adhesion;GO:0033627 cell adhesion mediated by integrin;GO:0098609 cell-cell adhesion;GO:0060326 cell chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FGZ7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FHW7-1", "uniprot_id": [ { "id": "A0A9J7FHW7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FHW7", "type": "external" } ], "mass": 23942.0, "length": 217, "protein_name": "Molybdopterin synthase catalytic subunit", "gene_name": "Mocs2", "organism": "Hamster", "refseq_name": "molybdopterin synthase catalytic subunit isoform X1", "refseq_ac": [ { "id": "XP_027257230", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257230", "type": "external" } ], "gene_names_uniprotkb": "Mocs2; MOCS2", "gene_names_refseq": "Mocs2", "protein_names_uniprotkb": "Molybdopterin synthase catalytic subunit; 2.8.1.12; MOCS2B; Molybdenum cofactor synthesis protein 2 large subunit; Molybdenum cofactor synthesis protein 2B", "protein_names_refseq": "molybdopterin synthase catalytic subunit isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100773226)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. Together with MBIP, inhibits the activity of stress kinase EIF2AK2/PKR; this may suppress JNK activation and subsequent stress-responsive transcription, or suppress eIF2a phosphorylation to favor translation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.8.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.1.12", "type": "external" } ], "go_molecular_function": "GO:0030366 molybdopterin synthase activity", "go_cellular_component": "GO:1990140 molybdopterin synthase complex", "go_biological_process": "GO:0006777 Mo-molybdopterin cofactor biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FHW7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FH77-1", "uniprot_id": [ { "id": "A0A9J7FH77_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FH77", "type": "external" } ], "mass": 24140.0, "length": 211, "protein_name": "Nucleoside diphosphate kinase 5", "gene_name": "Nme5", "organism": "Hamster", "refseq_name": "nucleoside diphosphate kinase homolog 5", "refseq_ac": [ { "id": "XP_027256515", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256515", "type": "external" } ], "gene_names_uniprotkb": "Nme5", "gene_names_refseq": "Nme5", "protein_names_uniprotkb": "Nucleoside diphosphate kinase 5; Putative 3'-5'-DNA exonuclease NDK5; Radial spoke head protein 23 homolog", "protein_names_refseq": "nucleoside diphosphate kinase homolog 5", "tax_id": 10029, "disease": "", "pathway": " (cge:100774762)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Functions as part of axonemal radial spoke complexes, which play an important part in the motility of sperm and cilia. In vitro, does not display nucleoside diphosphate kinase (NDPK) activity. Exhibits a 3'-5'-DNA exonuclease activity that removes single nucleotides from the 3' terminus of single-stranded DNA substrates and digests overhanging mismatched 3' termini from double-stranded DNA substrates, possibly participating in DNA nucleolytic processing. Confers protection from cell death mediated by BAX and alters the cellular levels of several antioxidant enzymes, including GPX5. Might be involved in spermiogenesis by enhancing the ability of late-stage spermatids to eliminate reactive oxygen species., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016787 hydrolase activity;GO:0004550 nucleoside diphosphate kinase activity", "go_cellular_component": "GO:0005929 cilium", "go_biological_process": "GO:0007286 spermatid development;GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0003341 cilium movement;GO:0006183 GTP biosynthetic process;GO:0006228 UTP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FH77-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FHC8-1", "uniprot_id": [ { "id": "A0A9J7FHC8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FHC8", "type": "external" } ], "mass": 151621.0, "length": 1366, "protein_name": "Tonsoku-like protein", "gene_name": "Tonsl", "organism": "Hamster", "refseq_name": "tonsoku-like protein isoform X1", "refseq_ac": [ { "id": "XP_027259985", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259985", "type": "external" } ], "gene_names_uniprotkb": "Tonsl", "gene_names_refseq": "Tonsl", "protein_names_uniprotkb": "Tonsoku-like protein; Inhibitor of kappa B-related protein; NF-kappa-B inhibitor-like protein 2; Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2", "protein_names_refseq": "tonsoku-like protein isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100761088)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the MMS22L-TONSL complex, a complex that promotes homologous recombination-mediated repair of double-strand breaks (DSBs) at stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication. It mediates the assembly of RAD51 filaments on single-stranded DNA (ssDNA): the MMS22L-TONSL complex is recruited to DSBs following histone replacement by histone chaperones and eviction of the replication protein A complex (RPA/RP-A) from DSBs. Following recruitment to DSBs, the TONSL-MMS22L complex promotes recruitment of RAD51 filaments and subsequent homologous recombination. Within the complex, TONSL acts as a histone reader, which recognizes and binds newly synthesized histones following their replacement by histone chaperones. Specifically binds histone H4 lacking methylation at 'Lys-20' (H4K20me0) and histone H3.1., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0043596 nuclear replication fork;GO:0005737 cytoplasm", "go_biological_process": "GO:0006325 chromatin organization;GO:0000724 double-strand break repair via homologous recombination;GO:0031297 replication fork processing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FHC8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FHE1-1", "uniprot_id": [ { "id": "A0A9J7FHE1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FHE1", "type": "external" } ], "mass": 70475.0, "length": 654, "protein_name": "Zinc transporter ZIP4", "gene_name": "Slc39a4", "organism": "Hamster", "refseq_name": "zinc transporter ZIP4", "refseq_ac": [ { "id": "XP_027260012", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260012", "type": "external" } ], "gene_names_uniprotkb": "Slc39a4", "gene_names_refseq": "Slc39a4", "protein_names_uniprotkb": "Zinc transporter ZIP4; Solute carrier family 39 member 4; Zrt- and Irt-like protein 4", "protein_names_refseq": "zinc transporter ZIP4", "tax_id": 10029, "disease": "", "pathway": " (cge:100755397)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Selective transporter that mediates the uptake of Zn(2+). Plays an essential role for dietary zinc uptake from small intestine. The Zn(2+) uniporter activity is regulated by zinc availability. Also exhibits polyspecific binding and transport of Cu(2+), Cd(2+) and possibly Ni(2+) but at higher concentrations., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0005385 zinc ion transmembrane transporter activity;GO:0046872 metal ion binding;GO:0140410 monoatomic cation:bicarbonate symporter activity", "go_cellular_component": "GO:0016324 apical plasma membrane;GO:0055038 recycling endosome membrane", "go_biological_process": "GO:0030003 intracellular monoatomic cation homeostasis;GO:0071578 zinc ion import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FHE1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FHF3-1", "uniprot_id": [ { "id": "A0A9J7FHF3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FHF3", "type": "external" } ], "mass": 107360.0, "length": 941, "protein_name": "Aminopeptidase", "gene_name": "Erap1", "organism": "Hamster", "refseq_name": "endoplasmic reticulum aminopeptidase 1", "refseq_ac": [ { "id": "XP_027257655", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257655", "type": "external" } ], "gene_names_uniprotkb": "Erap1", "gene_names_refseq": "Erap1", "protein_names_uniprotkb": "Aminopeptidase; 3.4.11.-", "protein_names_refseq": "endoplasmic reticulum aminopeptidase 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100756235)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042277 peptide binding;GO:0070006 metalloaminopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0043171 peptide catabolic process;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FHF3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FLA0-1", "uniprot_id": [ { "id": "A0A9J7FLA0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FLA0", "type": "external" } ], "mass": 106077.0, "length": 916, "protein_name": "Eukaryotic translation initiation factor 3 subunit C", "gene_name": "LOC100754077", "organism": "Hamster", "refseq_name": "eukaryotic translation initiation factor 3 subunit C isoform X1", "refseq_ac": [ { "id": "XP_016819193", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016819193", "type": "external" } ], "gene_names_uniprotkb": "LOC100754077; EIF3C; EIF3S8", "gene_names_refseq": "LOC100754077", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 3 subunit C; Eukaryotic translation initiation factor 3 subunit 8; eIF3 p110; eIF3c", "protein_names_refseq": "eukaryotic translation initiation factor 3 subunit C isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100754077)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 655 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003617044.1) and transcript sequence (IACG01095898.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression., [UniProtKB, HAMAP, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003743 translation initiation factor activity;GO:0031369 translation initiation factor binding", "go_cellular_component": "GO:0016282 eukaryotic 43S preinitiation complex;GO:0033290 eukaryotic 48S preinitiation complex;GO:0005852 eukaryotic translation initiation factor 3 complex;GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m", "go_biological_process": "GO:0001732 formation of cytoplasmic translation initiation complex", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FLA0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FHH1-1", "uniprot_id": [ { "id": "A0A9J7FHH1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FHH1", "type": "external" } ], "mass": 68031.0, "length": 590, "protein_name": "mRNA-capping enzyme", "gene_name": "Rngtt", "organism": "Hamster", "refseq_name": "mRNA-capping enzyme isoform X5", "refseq_ac": [ { "id": "XP_027259215", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259215", "type": "external" } ], "gene_names_uniprotkb": "Rngtt", "gene_names_refseq": "Rngtt", "protein_names_uniprotkb": "mRNA-capping enzyme; GTP--RNA guanylyltransferase; GTase; mRNA 5'-phosphatase", "protein_names_refseq": "mRNA-capping enzyme isoform X5", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.50", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.50", "type": "external" }, { "id": "3.6.1.74", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.74", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0005525 GTP binding;GO:0004721 phosphoprotein phosphatase activity;GO:0004651 polynucleotide 5'-phosphatase activity;GO:0004484 mRNA guanylyltransferase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006370 7-methylguanosine mRNA capping", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FHH1-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FHV3-1", "uniprot_id": [ { "id": "A0A9J7FHV3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FHV3", "type": "external" } ], "mass": 71080.0, "length": 642, "protein_name": "Tyrosine-protein kinase RYK", "gene_name": "LOC100757154", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: tyrosine-protein kinase RYK-like isoform X2", "refseq_ac": [ { "id": "XP_027257015", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257015", "type": "external" } ], "gene_names_uniprotkb": "LOC100757154", "gene_names_refseq": "LOC100757154", "protein_names_uniprotkb": "Tyrosine-protein kinase RYK; 2.7.10.1", "protein_names_refseq": "LOW QUALITY PROTEIN: tyrosine-protein kinase RYK-like isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100757154)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 6% of CDS bases frameshifts :: corrected 5 indels ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0007409 axonogenesis;GO:0010976 positive regulation of neuron projection development;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0060071 Wnt signaling pathway, planar cell polarity pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FHV3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FHY6-1", "uniprot_id": [ { "id": "A0A9J7FHY6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FHY6", "type": "external" } ], "mass": 76456.0, "length": 693, "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 2", "gene_name": "Tab2", "organism": "Hamster", "refseq_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 2", "refseq_ac": [ { "id": "XP_027257848", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257848", "type": "external" } ], "gene_names_uniprotkb": "Tab2", "gene_names_refseq": "Tab2", "protein_names_uniprotkb": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 2; Mitogen-activated protein kinase kinase kinase 7-interacting protein 2; TGF-beta-activated kinase 1-binding protein 2", "protein_names_refseq": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100759882)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Adapter required to activate the JNK and NF-kappa-B signaling pathways through the specific recognition of 'Lys-63'-linked polyubiquitin chains by its RanBP2-type zinc finger (NZF). Acts as an adapter linking MAP3K7/TAK1 and TRAF6 to 'Lys-63'-linked polyubiquitin chains. The RanBP2-type zinc finger (NZF) specifically recognizes Lys-63'-linked polyubiquitin chains unanchored or anchored to the substrate proteins such as RIPK1/RIP1 and RIPK2: this acts as a scaffold to organize a large signaling complex to promote autophosphorylation of MAP3K7/TAK1, and subsequent activation of I-kappa-B-kinase (IKK) core complex by MAP3K7/TAK1. Also recognizes and binds Lys-63'-linked polyubiquitin chains of heterotypic 'Lys-63'-/'Lys-48'-linked branched ubiquitin chains. Regulates the IL1-mediated translocation of NCOR1 out of the nucleus. Involved in heart development., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0016301 kinase activity;GO:0043130 ubiquitin binding;GO:0070530 K63-linked polyubiquitin modification-dependent protein binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005765 lysosomal membrane;GO:0010008 endosome membrane", "go_biological_process": "GO:0043123 positive regulation of canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FHY6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FHZ0-1", "uniprot_id": [ { "id": "A0A9J7FHZ0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FHZ0", "type": "external" } ], "mass": 69398.0, "length": 615, "protein_name": "Prolactin receptor", "gene_name": "Prlr", "organism": "Hamster", "refseq_name": "prolactin receptor isoform X1", "refseq_ac": [ { "id": "XP_016831999", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831999", "type": "external" } ], "gene_names_uniprotkb": "Prlr; PRLR", "gene_names_refseq": "Prlr", "protein_names_uniprotkb": "Prolactin receptor; PRL-R", "protein_names_refseq": "prolactin receptor isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100757415)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614037.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Dec 18, 2018 this sequence version replaced XP_016831999.1. COMPLETENESS: full length., [RefSeq]; This is a receptor for the anterior pituitary hormone prolactin., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0017046 peptide hormone binding;GO:0019955 cytokine binding;GO:0004925 prolactin receptor activity", "go_cellular_component": "GO:0043235 receptor complex;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FHZ0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FI25-1", "uniprot_id": [ { "id": "A0A9J7FI25_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FI25", "type": "external" } ], "mass": 67226.0, "length": 592, "protein_name": "Acyl-coenzyme A thioesterase 11", "gene_name": "Acot11", "organism": "Hamster", "refseq_name": "acyl-coenzyme A thioesterase 11", "refseq_ac": [ { "id": "XP_003495805", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495805", "type": "external" } ], "gene_names_uniprotkb": "Acot11", "gene_names_refseq": "Acot11", "protein_names_uniprotkb": "Acyl-coenzyme A thioesterase 11; 3.1.2.2; Acyl-CoA thioester hydrolase 11; Adipose-associated thioesterase; Brown fat-inducible thioesterase; Palmitoyl-coenzyme A thioesterase", "protein_names_refseq": "acyl-coenzyme A thioesterase 11", "tax_id": 10029, "disease": "", "pathway": " (cge:100752371)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoyl-CoA which are the main substrates in the mitochondrial beta-oxidation pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "3.1.2.14", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.14", "type": "external" }, { "id": "3.1.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.27", "type": "external" }, { "id": "3.1.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.1", "type": "external" }, { "id": "3.1.2.11", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.11", "type": "external" }, { "id": "3.1.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.3", "type": "external" }, { "id": "3.1.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.5", "type": "external" }, { "id": "3.5.2.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.2.6", "type": "external" }, { "id": "3.1.2.22", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.22", "type": "external" } ], "go_molecular_function": "GO:0052689 carboxylic ester hydrolase activity;GO:0008289 lipid binding;GO:0052816 long-chain fatty acyl-CoA hydrolase activity", "go_cellular_component": "GO:0005759 mitochondrial matrix;GO:0005829 cytosol", "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0006637 acyl-CoA metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FI25-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FI42-1", "uniprot_id": [ { "id": "A0A9J7FI42_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FI42", "type": "external" } ], "mass": 119194.0, "length": 1046, "protein_name": "F-box DNA helicase 1", "gene_name": "Fbh1", "organism": "Hamster", "refseq_name": "F-box DNA helicase 1 isoform X2", "refseq_ac": [ { "id": "XP_027260915", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260915", "type": "external" } ], "gene_names_uniprotkb": "Fbh1", "gene_names_refseq": "Fbh1", "protein_names_uniprotkb": "F-box DNA helicase 1; 5.6.2.4; DNA 3'-5' helicase 1; F-box only protein 18", "protein_names_refseq": "F-box DNA helicase 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100765086)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0043138 3'-5' DNA helicase activity;GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:2000042 negative regulation of double-strand break repair via homologous recombination;GO:0000724 double-strand break repair via homologous recombination;GO:0072429 response to intra-S DNA damage checkpoint signaling;GO:0031297 replication fork processing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FI42-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FI43-1", "uniprot_id": [ { "id": "A0A9J7FI43_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FI43", "type": "external" } ], "mass": 51416.0, "length": 456, "protein_name": "Bifunctional peptidase and arginyl-hydroxylase JMJD5", "gene_name": "Kdm8", "organism": "Hamster", "refseq_name": "bifunctional peptidase and arginyl-hydroxylase JMJD5 isoform X2", "refseq_ac": [ { "id": "XP_027260509", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260509", "type": "external" } ], "gene_names_uniprotkb": "Kdm8", "gene_names_refseq": "Kdm8", "protein_names_uniprotkb": "Bifunctional peptidase and arginyl-hydroxylase JMJD5; 1.14.11.73; JmjC domain-containing protein 5; Jumonji C domain-containing protein 5; L-arginine (3R)-hydroxylase KDM8", "protein_names_refseq": "bifunctional peptidase and arginyl-hydroxylase JMJD5 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762777)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.73", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.73", "type": "external" } ], "go_molecular_function": "GO:0051864 histone H3K36 demethylase activity;GO:0003682 chromatin binding;GO:0046872 metal ion binding;GO:0004177 aminopeptidase activity;GO:0106157 peptidyl-arginine 3-dioxygenase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0048511 rhythmic process;GO:0010468 regulation of gene expression;GO:0031648 protein destabilization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FI43-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FI53-1", "uniprot_id": [ { "id": "A0A9J7FI53_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FI53", "type": "external" } ], "mass": 77216.0, "length": 683, "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "Rad17", "organism": "Hamster", "refseq_name": "cell cycle checkpoint protein RAD17", "refseq_ac": [ { "id": "XP_027257407", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257407", "type": "external" } ], "gene_names_uniprotkb": "Rad17", "gene_names_refseq": "Rad17", "protein_names_uniprotkb": "Cell cycle checkpoint protein RAD17", "protein_names_refseq": "cell cycle checkpoint protein RAD17", "tax_id": 10029, "disease": "", "pathway": " (cge:100773436)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. Has a weak ATPase activity required for binding to chromatin. Participates in the recruitment of the 9-1-1 (RAD1-RAD9-HUS1) complex and RHNO1 onto chromatin, and in CHEK1 activation. Involved in homologous recombination by mediating recruitment of the MRN complex to DNA damage sites. May also serve as a sensor of DNA replication progression., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0003689 DNA clamp loader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0031389 Rad17 RFC-like complex", "go_biological_process": "GO:0006281 DNA repair;GO:0000077 DNA damage checkpoint signaling;GO:0033314 mitotic DNA replication checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FI53-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FI82-1", "uniprot_id": [ { "id": "A0A9J7FI82_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FI82", "type": "external" } ], "mass": 51035.0, "length": 454, "protein_name": "Ribosomal RNA-processing protein 8", "gene_name": "Rrp8", "organism": "Hamster", "refseq_name": "ribosomal RNA-processing protein 8 isoform X1", "refseq_ac": [ { "id": "XP_027260758", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260758", "type": "external" } ], "gene_names_uniprotkb": "Rrp8", "gene_names_refseq": "Rrp8", "protein_names_uniprotkb": "Ribosomal RNA-processing protein 8; 2.1.1.-", "protein_names_refseq": "ribosomal RNA-processing protein 8 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100759475)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008168 methyltransferase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0005677 chromatin silencing complex;GO:0033553 rDNA heterochromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0042149 cellular response to glucose starvation;GO:0006364 rRNA processing;GO:0032259 methylation;GO:0000183 rDNA heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FI82-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FIA3-1", "uniprot_id": [ { "id": "A0A9J7FIA3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FIA3", "type": "external" } ], "mass": 57784.0, "length": 502, "protein_name": "steroid 11beta-monooxygenase", "gene_name": "LOC107977023", "organism": "Hamster", "refseq_name": "cytochrome P450 11B2, mitochondrial isoform X2", "refseq_ac": [ { "id": "XP_027260103", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260103", "type": "external" } ], "gene_names_uniprotkb": "LOC107977023", "gene_names_refseq": "LOC107977023", "protein_names_uniprotkb": "steroid 11beta-monooxygenase; 1.14.15.4", "protein_names_refseq": "cytochrome P450 11B2, mitochondrial isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:107977023)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.15.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.15.4", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004507 steroid 11-beta-monooxygenase activity;GO:0047783 corticosterone 18-monooxygenase activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0008203 cholesterol metabolic process;GO:0006704 glucocorticoid biosynthetic process;GO:0071375 cellular response to peptide hormone stimulus;GO:0032342 aldosterone biosynthetic process;GO:0034650 cortisol metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FIA3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FM37-1", "uniprot_id": [ { "id": "A0A9J7FM37_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FM37", "type": "external" } ], "mass": 66676.0, "length": 575, "protein_name": "DnaJ homolog subfamily C member 1", "gene_name": "Dnajc1", "organism": "Hamster", "refseq_name": "dnaJ homolog subfamily C member 1 isoform X2", "refseq_ac": [ { "id": "XP_027261100", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261100", "type": "external" } ], "gene_names_uniprotkb": "Dnajc1", "gene_names_refseq": "Dnajc1", "protein_names_uniprotkb": "DnaJ homolog subfamily C member 1; DnaJ protein homolog MTJ1", "protein_names_refseq": "dnaJ homolog subfamily C member 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100751540)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May modulate protein synthesis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0031965 nuclear membrane;GO:0005789 endoplasmic reticulum membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0051246 regulation of protein metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FM37-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FIG5-1", "uniprot_id": [ { "id": "A0A9J7FIG5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FIG5", "type": "external" } ], "mass": 107556.0, "length": 985, "protein_name": "Poly [ADP-ribose] polymerase", "gene_name": "Parp10", "organism": "Hamster", "refseq_name": "protein mono-ADP-ribosyltransferase PARP10 isoform X1", "refseq_ac": [ { "id": "XP_016833732", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016833732", "type": "external" } ], "gene_names_uniprotkb": "Parp10", "gene_names_refseq": "Parp10", "protein_names_uniprotkb": "Poly [ADP-ribose] polymerase; 2.4.2.-; PARP", "protein_names_refseq": "protein mono-ADP-ribosyltransferase PARP10 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100757141)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614411.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; ADP-ribosyltransferase that mediates mono-ADP-ribosylation of glutamate and aspartate residues on target proteins. In contrast to PARP1 and PARP2, it is not able to mediate poly-ADP-ribosylation. Catalyzes mono-ADP-ribosylation of GSK3B, leading to negatively regulate GSK3B kinase activity. Involved in translesion DNA synthesis in response to DNA damage via its interaction with PCNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity;GO:0003714 transcription corepressor activity;GO:0016779 nucleotidyltransferase activity;GO:0003950 NAD+ poly-ADP-ribosyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006281 DNA repair;GO:0010629 negative regulation of gene expression;GO:0070212 protein poly-ADP-ribosylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FIG5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FNB9-1", "uniprot_id": [ { "id": "A0A9J7FNB9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FNB9", "type": "external" } ], "mass": 65884.0, "length": 573, "protein_name": "Optineurin", "gene_name": "Optn", "organism": "Hamster", "refseq_name": "optineurin isoform X1", "refseq_ac": [ { "id": "XP_003496453", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496453", "type": "external" } ], "gene_names_uniprotkb": "Optn", "gene_names_refseq": "Optn", "protein_names_uniprotkb": "Optineurin", "protein_names_refseq": "optineurin isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100773283)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 177 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613621.1) and transcript sequence (IACG01092204.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May act by regulating membrane trafficking and cellular morphogenesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0070530 K63-linked polyubiquitin modification-dependent protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005794 Golgi apparatus;GO:0048471 perinuclear region of cytoplasm;GO:0055037 recycling endosome;GO:0005776 autophagosome", "go_biological_process": "GO:0006914 autophagy;GO:0090161 Golgi ribbon formation;GO:0034067 protein localization to Golgi apparatus;GO:0043122 regulation of canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FNB9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FN43-1", "uniprot_id": [ { "id": "A0A9J7FN43_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FN43", "type": "external" } ], "mass": 216466.0, "length": 1956, "protein_name": "Rho GTPase-activating protein 21", "gene_name": "Arhgap21", "organism": "Hamster", "refseq_name": "rho GTPase-activating protein 21 isoform X1", "refseq_ac": [ { "id": "XP_027261132", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261132", "type": "external" } ], "gene_names_uniprotkb": "Arhgap21", "gene_names_refseq": "Arhgap21", "protein_names_uniprotkb": "Rho GTPase-activating protein 21; Rho GTPase-activating protein 10; Rho-type GTPase-activating protein 21", "protein_names_refseq": "rho GTPase-activating protein 21 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100766620)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Functions as a GTPase-activating protein (GAP) for RHOA and CDC42. Downstream partner of ARF1 which may control Golgi apparatus structure and function. Also required for CTNNA1 recruitment to adherens junctions., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0030659 cytoplasmic vesicle membrane;GO:0070161 anchoring junction", "go_biological_process": "GO:0007165 signal transduction;GO:0051645 Golgi localization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FN43-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FJ37-1", "uniprot_id": [ { "id": "A0A9J7FJ37_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FJ37", "type": "external" } ], "mass": 125829.0, "length": 1137, "protein_name": "DNA helicase MCM9", "gene_name": "Mcm9", "organism": "Hamster", "refseq_name": "DNA helicase MCM9 isoform X1", "refseq_ac": [ { "id": "XP_016835243", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016835243", "type": "external" } ], "gene_names_uniprotkb": "Mcm9", "gene_names_refseq": "Mcm9", "protein_names_uniprotkb": "DNA helicase MCM9; 5.6.2.4; DNA 3'-5' helicase MCM9; Mini-chromosome maintenance deficient domain-containing protein 1; Minichromosome maintenance 9", "protein_names_refseq": "DNA helicase MCM9 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100762661)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 270 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614914.1) and transcript sequence (IACG01046663.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003697 single-stranded DNA binding;GO:0017116 single-stranded DNA helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome;GO:0097362 MCM8-MCM9 complex;GO:0042555 MCM complex", "go_biological_process": "GO:0000724 double-strand break repair via homologous recombination;GO:0036298 recombinational interstrand cross-link repair;GO:0070716 mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FJ37-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FJA8-1", "uniprot_id": [ { "id": "A0A9J7FJA8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FJA8", "type": "external" } ], "mass": 125112.0, "length": 1115, "protein_name": "Glutamate receptor", "gene_name": "Grin3a", "organism": "Hamster", "refseq_name": "glutamate receptor ionotropic, NMDA 3A isoform X2", "refseq_ac": [ { "id": "XP_027258897", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258897", "type": "external" } ], "gene_names_uniprotkb": "Grin3a", "gene_names_refseq": "Grin3a", "protein_names_uniprotkb": "Glutamate receptor", "protein_names_refseq": "glutamate receptor ionotropic, NMDA 3A isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100758947)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0004972 NMDA glutamate receptor activity", "go_cellular_component": "GO:0014069 postsynaptic density;GO:0045211 postsynaptic membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FJA8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FJK0-1", "uniprot_id": [ { "id": "A0A9J7FJK0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FJK0", "type": "external" } ], "mass": 44970.0, "length": 395, "protein_name": "Galactose-1-phosphate uridylyltransferase", "gene_name": "Galt", "organism": "Hamster", "refseq_name": "galactose-1-phosphate uridylyltransferase isoform X2", "refseq_ac": [ { "id": "XP_027259108", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259108", "type": "external" } ], "gene_names_uniprotkb": "Galt", "gene_names_refseq": "Galt", "protein_names_uniprotkb": "Galactose-1-phosphate uridylyltransferase; 2.7.7.12", "protein_names_refseq": "galactose-1-phosphate uridylyltransferase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100752522)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays an important role in galactose metabolism., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.12", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0008108 UDP-glucose:hexose-1-phosphate uridylyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0033499 galactose catabolic process via UDP-galactose, Leloir pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FJK0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FJX6-1", "uniprot_id": [ { "id": "A0A9J7FJX6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FJX6", "type": "external" } ], "mass": 105073.0, "length": 919, "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "Wwp1", "organism": "Hamster", "refseq_name": "NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X2", "refseq_ac": [ { "id": "XP_027259372", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259372", "type": "external" } ], "gene_names_uniprotkb": "Wwp1", "gene_names_refseq": "Wwp1", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase; 2.3.2.26", "protein_names_refseq": "NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100757929)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0070161 anchoring junction;GO:0005737 cytoplasm", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FJX6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FJP0-1", "uniprot_id": [ { "id": "A0A9J7FJP0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FJP0", "type": "external" } ], "mass": 60203.0, "length": 542, "protein_name": "Telomeric repeat-binding factor 2", "gene_name": "Terf2", "organism": "Hamster", "refseq_name": "telomeric repeat-binding factor 2 isoform X2", "refseq_ac": [ { "id": "XP_027261740", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261740", "type": "external" } ], "gene_names_uniprotkb": "Terf2", "gene_names_refseq": "Terf2", "protein_names_uniprotkb": "Telomeric repeat-binding factor 2; TTAGGG repeat-binding factor 2; Telomeric DNA-binding protein", "protein_names_refseq": "telomeric repeat-binding factor 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762546)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0098505 G-rich strand telomeric DNA binding;GO:0042803 protein homodimerization activity;GO:0044877 protein-containing complex binding;GO:0003691 double-stranded telomeric DNA binding;GO:0003720 telomerase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0070187 shelterin complex", "go_biological_process": "GO:0031848 protection from non-homologous end joining at telomere;GO:0070198 protein localization to chromosome, telomeric region;GO:0061820 telomeric D-loop disassembly;GO:0032210 regulation of telomere maintenance via telomerase;GO:0032206 positive regulation of telomere maintenance", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FJP0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FM12-1", "uniprot_id": [ { "id": "A0A9J7FM12_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FM12", "type": "external" } ], "mass": 46609.0, "length": 410, "protein_name": "Histone-lysine N-methyltransferase", "gene_name": "Suv39h2", "organism": "Hamster", "refseq_name": "histone-lysine N-methyltransferase SUV39H2 isoform X2", "refseq_ac": [ { "id": "XP_027261017", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261017", "type": "external" } ], "gene_names_uniprotkb": "Suv39h2", "gene_names_refseq": "Suv39h2", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase; 2.1.1.-", "protein_names_refseq": "histone-lysine N-methyltransferase SUV39H2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100755145)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.366", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.366", "type": "external" }, { "id": "2.1.1.367", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.367", "type": "external" }, { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0140949 histone H3K9 trimethyltransferase activity;GO:0140947 histone H3K9me2 methyltransferase activity;GO:0046872 metal ion binding;GO:0046974 histone H3K9 methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000775 chromosome, centromeric region;GO:0000785 chromatin;GO:0005694 chromosome", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0045892 negative regulation of DNA-templated transcription;GO:0032259 methylation;GO:0045814 negative regulation of gene expression, epigenetic", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FM12-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FKI1-1", "uniprot_id": [ { "id": "A0A9J7FKI1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FKI1", "type": "external" } ], "mass": 112939.0, "length": 1001, "protein_name": "GATOR2 complex protein WDR59", "gene_name": "Wdr59", "organism": "Hamster", "refseq_name": "GATOR complex protein WDR59 isoform X1", "refseq_ac": [ { "id": "XP_027261836", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261836", "type": "external" } ], "gene_names_uniprotkb": "Wdr59", "gene_names_refseq": "Wdr59", "protein_names_uniprotkb": "GATOR2 complex protein WDR59; WD repeat-containing protein 59", "protein_names_refseq": "GATOR complex protein WDR59 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100771324)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; As a component of the GATOR2 complex, functions as an activator of the amino acid-sensing branch of the mTORC1 signaling pathway. The GATOR2 complex indirectly activates mTORC1 through the inhibition of the GATOR1 subcomplex. GATOR2 probably acts as an E3 ubiquitin-protein ligase toward GATOR1. In the presence of abundant amino acids, the GATOR2 complex mediates ubiquitination of the NPRL2 core component of the GATOR1 complex, leading to GATOR1 inactivation. In the absence of amino acids, GATOR2 is inhibited, activating the GATOR1 complex., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0035591 signaling adaptor activity", "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0035859 Seh1-associated complex", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0034198 cellular response to amino acid starvation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FKI1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FK45-1", "uniprot_id": [ { "id": "A0A9J7FK45_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FK45", "type": "external" } ], "mass": 192360.0, "length": 1722, "protein_name": "Gag-Pol polyprotein", "gene_name": "LOC113834687", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: uncharacterized protein LOC113834687", "refseq_ac": [ { "id": "XP_027261909", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261909", "type": "external" } ], "gene_names_uniprotkb": "LOC113834687", "gene_names_refseq": "LOC113834687", "protein_names_uniprotkb": "Gag-Pol polyprotein; 2.7.7.49; 3.1.26.4", "protein_names_refseq": "LOW QUALITY PROTEIN: uncharacterized protein LOC113834687", "tax_id": 10029, "disease": "", "pathway": " (cge:113834687)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 2% of CDS bases frameshifts :: corrected 6 indels internal stop codons :: corrected 4 genomic stop codons ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes viral DNA integration into the host chromosome, by performing a series of DNA cutting and joining reactions. This enzyme activity takes place after virion entry into a cell and reverse transcription of the RNA genome in dsDNA. The first step in the integration process is 3' processing. This step requires a complex comprising the viral genome, matrix protein and integrase. This complex is called the pre-integration complex (PIC). The integrase protein removes 2 nucleotides from each 3' end of the viral DNA, leaving recessed CA OH's at the 3' ends. In the second step that requires cell division, the PIC enters cell nucleus. In the third step, termed strand transfer, the integrase protein joins the previously processed 3' ends to the 5' ends of strands of target cellular DNA at the site of integration. The last step is viral DNA integration into host chromosome., [UniProtKB, UniProtKB]; Forms the spherical core of the virion that encapsulates the genomic RNA-nucleocapsid complex., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003964 RNA-directed DNA polymerase activity;GO:0003677 DNA binding;GO:0003723 RNA binding;GO:0008270 zinc ion binding;GO:0004523 RNA-DNA hybrid ribonuclease activity", "go_cellular_component": "", "go_biological_process": "GO:0006310 DNA recombination;GO:0006508 proteolysis;GO:0019068 virion assembly;GO:0015074 DNA integration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FK45-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FK97-1", "uniprot_id": [ { "id": "A0A9J7FK97_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FK97", "type": "external" } ], "mass": 36163.0, "length": 321, "protein_name": "Beta-1,3-N-acetylglucosaminyltransferase", "gene_name": "Mfng", "organism": "Hamster", "refseq_name": "beta-1,3-N-acetylglucosaminyltransferase manic fringe", "refseq_ac": [ { "id": "XP_027259760", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259760", "type": "external" } ], "gene_names_uniprotkb": "Mfng", "gene_names_refseq": "Mfng", "protein_names_uniprotkb": "Beta-1,3-N-acetylglucosaminyltransferase; 2.4.1.222; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase", "protein_names_refseq": "beta-1,3-N-acetylglucosaminyltransferase manic fringe", "tax_id": 10029, "disease": "", "pathway": " (cge:100762875)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.222", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.222", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0007389 pattern specification process;GO:0008593 regulation of Notch signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FK97-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FKB7-1", "uniprot_id": [ { "id": "A0A9J7FKB7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FKB7", "type": "external" } ], "mass": 139929.0, "length": 1316, "protein_name": "Sal-like protein 1", "gene_name": "Sall1", "organism": "Hamster", "refseq_name": "sal-like protein 1 isoform X2", "refseq_ac": [ { "id": "XP_027261358", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261358", "type": "external" } ], "gene_names_uniprotkb": "Sall1", "gene_names_refseq": "Sall1", "protein_names_uniprotkb": "Sal-like protein 1", "protein_names_refseq": "sal-like protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100757204)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Transcriptional repressor involved in organogenesis. Plays an essential role in ureteric bud invasion during kidney development., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0000792 heterochromatin", "go_biological_process": "GO:0035295 tube development;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0007507 heart development;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FKB7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FKE3-1", "uniprot_id": [ { "id": "A0A9J7FKE3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FKE3", "type": "external" } ], "mass": 406310.0, "length": 3715, "protein_name": "Zinc finger homeobox protein 3", "gene_name": "Zfhx3", "organism": "Hamster", "refseq_name": "zinc finger homeobox protein 3 isoform X3", "refseq_ac": [ { "id": "XP_027261756", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261756", "type": "external" } ], "gene_names_uniprotkb": "Zfhx3", "gene_names_refseq": "Zfhx3", "protein_names_uniprotkb": "Zinc finger homeobox protein 3; AT motif-binding factor 1; AT-binding transcription factor 1; Alpha-fetoprotein enhancer-binding protein; Zinc finger homeodomain protein 3", "protein_names_refseq": "zinc finger homeobox protein 3 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100759927)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007517 muscle organ development;GO:0045664 regulation of neuron differentiation;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FKE3-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FKF4-1", "uniprot_id": [ { "id": "A0A9J7FKF4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FKF4", "type": "external" } ], "mass": 54079.0, "length": 486, "protein_name": "5-hydroxytryptamine receptor 7", "gene_name": "Htr7", "organism": "Hamster", "refseq_name": "5-hydroxytryptamine receptor 7 isoform X3", "refseq_ac": [ { "id": "XP_027262153", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262153", "type": "external" } ], "gene_names_uniprotkb": "Htr7", "gene_names_refseq": "Htr7", "protein_names_uniprotkb": "5-hydroxytryptamine receptor 7; 5-HT-X; Serotonin receptor 7", "protein_names_refseq": "5-hydroxytryptamine receptor 7 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:103163243)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; G-protein coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR7 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004993 G protein-coupled serotonin receptor activity;GO:0030594 neurotransmitter receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045202 synapse;GO:0030425 dendrite", "go_biological_process": "GO:0006939 smooth muscle contraction;GO:0043410 positive regulation of MAPK cascade;GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0007268 chemical synaptic transmission;GO:0007623 circadian rhythm", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FKF4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FKR7-1", "uniprot_id": [ { "id": "A0A9J7FKR7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FKR7", "type": "external" } ], "mass": 75429.0, "length": 657, "protein_name": "THO complex subunit 1", "gene_name": "Thoc1", "organism": "Hamster", "refseq_name": "THO complex subunit 1 isoform X1", "refseq_ac": [ { "id": "XP_007645891", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645891", "type": "external" } ], "gene_names_uniprotkb": "Thoc1", "gene_names_refseq": "Thoc1", "protein_names_uniprotkb": "THO complex subunit 1; Nuclear matrix protein p84", "protein_names_refseq": "THO complex subunit 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100770844)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 100 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614335.1) and transcript sequence (JI881483.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. Required for efficient export of polyadenylated RNA. The THOC1-THOC2-THOC3 core complex alone is sufficient to bind export factor NXF1-NXT1 and promote ATPase activity of DDX39B. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NXF1 pathway. Regulates transcriptional elongation of a subset of genes. Involved in genome stability by preventing co-transcriptional R-loop formation. May play a role in hair cell formation, hence may be involved in hearing., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0016363 nuclear matrix;GO:0000445 THO complex part of transcription export complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006397 mRNA processing;GO:0006406 mRNA export from nucleus;GO:0007165 signal transduction;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FKR7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FP75-1", "uniprot_id": [ { "id": "A0A9J7FP75_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FP75", "type": "external" } ], "mass": 27484.0, "length": 240, "protein_name": "Glutathione S-transferase omega", "gene_name": "Gsto1", "organism": "Hamster", "refseq_name": "glutathione S-transferase omega-1 isoform X5", "refseq_ac": [ { "id": "XP_027262854", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262854", "type": "external" } ], "gene_names_uniprotkb": "Gsto1", "gene_names_refseq": "Gsto1", "protein_names_uniprotkb": "Glutathione S-transferase omega; 1.20.4.2; 1.8.5.1; 2.5.1.18; GSTO; Glutathione-dependent dehydroascorbate reductase; Monomethylarsonic acid reductase", "protein_names_refseq": "glutathione S-transferase omega-1 isoform X5", "tax_id": 10029, "disease": "", "pathway": " (cge:100758427)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.5.1.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.18", "type": "external" }, { "id": "5.2.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.2", "type": "external" }, { "id": "5.3.99.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.99.2", "type": "external" }, { "id": "1.20.4.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.20.4.2", "type": "external" }, { "id": "1.8.5.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.5.1", "type": "external" }, { "id": "1.11.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.-", "type": "external" }, { "id": "4.4.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:4.4.1.20", "type": "external" } ], "go_molecular_function": "GO:0004364 glutathione transferase activity;GO:0045174 glutathione dehydrogenase (ascorbate) activity;GO:0050610 methylarsonate reductase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0019852 L-ascorbic acid metabolic process;GO:0006749 glutathione metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FP75-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FKU4-1", "uniprot_id": [ { "id": "A0A9J7FKU4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FKU4", "type": "external" } ], "mass": 117737.0, "length": 1020, "protein_name": "Insulin-degrading enzyme", "gene_name": "Ide", "organism": "Hamster", "refseq_name": "insulin-degrading enzyme isoform X4", "refseq_ac": [ { "id": "XP_027262121", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262121", "type": "external" } ], "gene_names_uniprotkb": "Ide", "gene_names_refseq": "Ide", "protein_names_uniprotkb": "Insulin-degrading enzyme; 3.4.24.56; Insulin protease; Insulysin", "protein_names_refseq": "insulin-degrading enzyme isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100763752)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005739 mitochondrion;GO:0005782 peroxisomal matrix;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0050435 amyloid-beta metabolic process;GO:0042447 hormone catabolic process;GO:0043171 peptide catabolic process;GO:0051603 proteolysis involved in protein catabolic process;GO:0097242 amyloid-beta clearance", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FKU4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FLD2-1", "uniprot_id": [ { "id": "A0A9J7FLD2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FLD2", "type": "external" } ], "mass": 59896.0, "length": 550, "protein_name": "pantothenate kinase", "gene_name": "Pank1", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: pantothenate kinase 1 isoform X2", "refseq_ac": [ { "id": "XP_027262164", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262164", "type": "external" } ], "gene_names_uniprotkb": "Pank1", "gene_names_refseq": "Pank1", "protein_names_uniprotkb": "pantothenate kinase; 2.7.1.33", "protein_names_refseq": "LOW QUALITY PROTEIN: pantothenate kinase 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100768798)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the phosphorylation of pantothenate to generate 4'-phosphopantothenate in the first and rate-determining step of coenzyme A (CoA) synthesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.33", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.33", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004594 pantothenate kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0015937 coenzyme A biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FLD2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FLY5-1", "uniprot_id": [ { "id": "A0A9J7FLY5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FLY5", "type": "external" } ], "mass": 60882.0, "length": 549, "protein_name": "Mitogen-activated protein kinase 15", "gene_name": "Mapk15", "organism": "Hamster", "refseq_name": "mitogen-activated protein kinase 15", "refseq_ac": [ { "id": "XP_027260027", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260027", "type": "external" } ], "gene_names_uniprotkb": "Mapk15", "gene_names_refseq": "Mapk15", "protein_names_uniprotkb": "Mitogen-activated protein kinase 15; 2.7.11.24; Extracellular signal-regulated kinase 7; Extracellular signal-regulated kinase 8", "protein_names_refseq": "mitogen-activated protein kinase 15", "tax_id": 10029, "disease": "", "pathway": " (cge:100758872)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004707 MAP kinase activity", "go_cellular_component": "GO:0005923 bicellular tight junction;GO:0005776 autophagosome;GO:0005814 centriole", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FLY5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FM10-1", "uniprot_id": [ { "id": "A0A9J7FM10_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FM10", "type": "external" } ], "mass": 117400.0, "length": 1062, "protein_name": "Integrin alpha-8", "gene_name": "Itga8", "organism": "Hamster", "refseq_name": "integrin alpha-8 isoform X1", "refseq_ac": [ { "id": "XP_027261030", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261030", "type": "external" } ], "gene_names_uniprotkb": "Itga8", "gene_names_refseq": "Itga8", "protein_names_uniprotkb": "Integrin alpha-8", "protein_names_refseq": "integrin alpha-8 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100769007)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0009897 external side of plasma membrane;GO:0008305 integrin complex", "go_biological_process": "GO:0007229 integrin-mediated signaling pathway;GO:0007399 nervous system development;GO:0030154 cell differentiation;GO:0001822 kidney development;GO:0007160 cell-matrix adhesion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FM10-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FM40-1", "uniprot_id": [ { "id": "A0A9J7FM40_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FM40", "type": "external" } ], "mass": 24395.0, "length": 225, "protein_name": "Acyl-protein thioesterase 1", "gene_name": "LOC100764608", "organism": "Hamster", "refseq_name": "acyl-protein thioesterase 1-like isoform X2", "refseq_ac": [ { "id": "XP_027263823", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263823", "type": "external" } ], "gene_names_uniprotkb": "LOC100764608", "gene_names_refseq": "LOC100764608", "protein_names_uniprotkb": "Acyl-protein thioesterase 1; 3.1.2.22; Lysophospholipase 1; Lysophospholipase I; Palmitoyl-protein hydrolase", "protein_names_refseq": "acyl-protein thioesterase 1-like isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100764608)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Acts as an acyl-protein thioesterase. Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Acts as a palmitoyl thioesterase that catalyzes depalmitoylation of proteins, such as ADRB2, KCNMA1 and SQSTM1. Acts as a negative regulator of autophagy by mediating palmitoylation of SQSTM1, decreasing affinity between SQSTM1 and ATG8 proteins and recruitment of ubiquitinated cargo proteins to autophagosomes. Acts as a lysophospholipase and hydrolyzes lysophosphatidylcholine (lyso-PC). Also hydrolyzes lysophosphatidylethanolamine (lyso-PE), lysophosphatidylinositol (lyso-PI) and lysophosphatidylserine (lyso-PS). Has much higher thioesterase activity than lysophospholipase activity. Contributes to the production of lysophosphatidic acid (LPA) during blood coagulation by recognizing and cleaving plasma phospholipids to generate lysophospholipids which in turn act as substrates for ENPP2 to produce LPA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "3.1.2.22", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.22", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "3.1.1.93", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.93", "type": "external" }, { "id": "2.3.1.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.21", "type": "external" }, { "id": "3.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.-", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "3.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0052689 carboxylic ester hydrolase activity;GO:0008474 palmitoyl-(protein) hydrolase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0031965 nuclear membrane", "go_biological_process": "GO:0006631 fatty acid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FM40-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FM77-1", "uniprot_id": [ { "id": "A0A9J7FM77_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FM77", "type": "external" } ], "mass": 80950.0, "length": 723, "protein_name": "ATP-dependent zinc metalloprotease YME1L1", "gene_name": "Yme1l1", "organism": "Hamster", "refseq_name": "ATP-dependent zinc metalloprotease YME1L1 isoform X1", "refseq_ac": [ { "id": "XP_027261170", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261170", "type": "external" } ], "gene_names_uniprotkb": "Yme1l1", "gene_names_refseq": "Yme1l1", "protein_names_uniprotkb": "ATP-dependent zinc metalloprotease YME1L1; ATP-dependent metalloprotease FtsH1; YME1-like protein 1", "protein_names_refseq": "ATP-dependent zinc metalloprotease YME1L1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100770453)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0004176 ATP-dependent peptidase activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0010636 positive regulation of mitochondrial fusion;GO:0007005 mitochondrion organization;GO:0034982 mitochondrial protein processing;GO:0006515 protein quality control for misfolded or incompletely synthesized proteins;GO:0008283 cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FM77-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FMB0-1", "uniprot_id": [ { "id": "A0A9J7FMB0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FMB0", "type": "external" } ], "mass": 42145.0, "length": 384, "protein_name": "Dual specificity protein phosphatase", "gene_name": "Dusp5", "organism": "Hamster", "refseq_name": "dual specificity protein phosphatase 5 isoform X2", "refseq_ac": [ { "id": "XP_027262825", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262825", "type": "external" } ], "gene_names_uniprotkb": "Dusp5", "gene_names_refseq": "Dusp5", "protein_names_uniprotkb": "Dual specificity protein phosphatase; 3.1.3.16; 3.1.3.48", "protein_names_refseq": "dual specificity protein phosphatase 5 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100758694)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Dual specificity protein phosphatase; active with phosphotyrosine, phosphoserine and phosphothreonine residues. The highest relative activity is toward ERK1., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.52", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.52", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21", "type": "external" }, { "id": "3.1.3.74", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.74", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" } ], "go_molecular_function": "GO:0004722 protein serine/threonine phosphatase activity;GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0043409 negative regulation of MAPK cascade;GO:0001706 endoderm formation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FMB0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FS02-1", "uniprot_id": [ { "id": "A0A9J7FS02_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FS02", "type": "external" } ], "mass": 162620.0, "length": 1451, "protein_name": "Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1", "gene_name": "Arap1", "organism": "Hamster", "refseq_name": "arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 isoform X4", "refseq_ac": [ { "id": "XP_027263624", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263624", "type": "external" } ], "gene_names_uniprotkb": "Arap1", "gene_names_refseq": "Arap1", "protein_names_uniprotkb": "Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1; Centaurin-delta-2", "protein_names_refseq": "arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100774696)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0002102 podosome;GO:0001726 ruffle;GO:0005795 Golgi stack", "go_biological_process": "GO:0007165 signal transduction;GO:0030100 regulation of endocytosis;GO:0008360 regulation of cell shape;GO:0051130 positive regulation of cellular component organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FS02-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FMH8-1", "uniprot_id": [ { "id": "A0A9J7FMH8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FMH8", "type": "external" } ], "mass": 74271.0, "length": 676, "protein_name": "Cytoplasmic polyadenylation element-binding protein 1", "gene_name": "Cpeb1", "organism": "Hamster", "refseq_name": "cytoplasmic polyadenylation element-binding protein 1 isoform X2", "refseq_ac": [ { "id": "XP_027264086", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264086", "type": "external" } ], "gene_names_uniprotkb": "Cpeb1", "gene_names_refseq": "Cpeb1", "protein_names_uniprotkb": "Cytoplasmic polyadenylation element-binding protein 1", "protein_names_refseq": "cytoplasmic polyadenylation element-binding protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100759655)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the 3'-UTR of mRNAs. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradation. Involved in the transport of CPE-containing mRNA to dendrites; those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses. Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation. Induces the assembly of stress granules in the absence of stress. Required for cell cycle progression, specifically for prophase entry., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000900 mRNA regulatory element binding translation repressor activity;GO:0046872 metal ion binding;GO:0008135 translation factor activity, RNA binding;GO:0043022 ribosome binding;GO:0003730 mRNA 3'-UTR binding", "go_cellular_component": "GO:0005634 nucleus;GO:0014069 postsynaptic density;GO:0015630 microtubule cytoskeleton;GO:0043005 neuron projection;GO:0000932 P-body", "go_biological_process": "GO:0006397 mRNA processing;GO:2000766 negative regulation of cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FMH8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FMK1-1", "uniprot_id": [ { "id": "A0A9J7FMK1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FMK1", "type": "external" } ], "mass": 43702.0, "length": 380, "protein_name": "Hypoxia-inducible factor 1-alpha inhibitor", "gene_name": "Hif1an", "organism": "Hamster", "refseq_name": "hypoxia-inducible factor 1-alpha inhibitor isoform X2", "refseq_ac": [ { "id": "XP_027263026", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263026", "type": "external" } ], "gene_names_uniprotkb": "Hif1an", "gene_names_refseq": "Hif1an", "protein_names_uniprotkb": "Hypoxia-inducible factor 1-alpha inhibitor; 1.14.11.30; 1.14.11.n4; Hypoxia-inducible factor asparagine hydroxylase", "protein_names_refseq": "hypoxia-inducible factor 1-alpha inhibitor isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100752342)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 9% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027263026.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.30", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.30", "type": "external" }, { "id": "1.14.11.n4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.n4", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0036139 peptidyl-histidine dioxygenase activity;GO:0036140 [protein]-asparagine 3-dioxygenase activity;GO:0071532 ankyrin repeat binding", "go_cellular_component": "GO:0005634 nucleus;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0050793 regulation of developmental process;GO:0006351 DNA-templated transcription;GO:0045746 negative regulation of Notch signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FMK1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FMQ0-1", "uniprot_id": [ { "id": "A0A9J7FMQ0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FMQ0", "type": "external" } ], "mass": 31284.0, "length": 271, "protein_name": "Ubiquitin thioesterase", "gene_name": "Otub1", "organism": "Hamster", "refseq_name": "ubiquitin thioesterase OTUB1 isoform X1", "refseq_ac": [ { "id": "XP_007649989", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649989", "type": "external" } ], "gene_names_uniprotkb": "Otub1", "gene_names_refseq": "Otub1", "protein_names_uniprotkb": "Ubiquitin thioesterase; 3.4.19.12", "protein_names_refseq": "ubiquitin thioesterase OTUB1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100758975)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 95 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615068.1) and transcript sequence (JP061793.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Hydrolase that can specifically remove compared to 'Lys-48'-linked conjugated ubiquitin from proteins and plays an important regulatory role at the level of protein turnover by preventing degradation. Regulator of T-cell anergy, a phenomenon that occurs when T-cells are rendered unresponsive to antigen rechallenge and no longer respond to their cognate antigen. Acts via its interaction with RNF128/GRAIL. Surprisingly, it regulates RNF128-mediated ubiquitination, but does not deubiquitinate polyubiquitinated RNF128. Deubiquitinates estrogen receptor alpha (ESR1). Mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains, but not 'Lys-63'-linked polyubiquitin chains. Not able to cleave di-ubiquitin. Also capable of removing NEDD8 from NEDD8 conjugates, but with a much lower preference compared to 'Lys-48'-linked ubiquitin., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043130 ubiquitin binding;GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:2000780 negative regulation of double-strand break repair;GO:0006281 DNA repair;GO:0006508 proteolysis;GO:0002250 adaptive immune response;GO:0071108 protein K48-linked deubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FMQ0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FMQ8-1", "uniprot_id": [ { "id": "A0A9J7FMQ8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FMQ8", "type": "external" } ], "mass": 151787.0, "length": 1397, "protein_name": "Capping protein, Arp2/3 and myosin-I linker protein 2", "gene_name": "Carmil2", "organism": "Hamster", "refseq_name": "capping protein, Arp2/3 and myosin-I linker protein 2 isoform X2", "refseq_ac": [ { "id": "XP_027261642", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261642", "type": "external" } ], "gene_names_uniprotkb": "Carmil2", "gene_names_refseq": "Carmil2", "protein_names_uniprotkb": "Capping protein, Arp2/3 and myosin-I linker protein 2; Capping protein regulator and myosin 1 linker 2; F-actin-uncapping protein RLTPR; Leucine-rich repeat-containing protein 16C; RGD, leucine-rich repeat, tropomodulin and proline-rich-containing protein", "protein_names_refseq": "capping protein, Arp2/3 and myosin-I linker protein 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767020)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0015629 actin cytoskeleton;GO:0030027 lamellipodium;GO:0001726 ruffle", "go_biological_process": "GO:0016477 cell migration;GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FMQ8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FNC8-1", "uniprot_id": [ { "id": "A0A9J7FNC8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FNC8", "type": "external" } ], "mass": 211649.0, "length": 1919, "protein_name": "Autophagy-related protein 2 homolog A isoform X4", "gene_name": "Atg2a", "organism": "Hamster", "refseq_name": "autophagy-related protein 2 homolog A isoform X4", "refseq_ac": [ { "id": "XP_027264308", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264308", "type": "external" } ], "gene_names_uniprotkb": "Atg2a", "gene_names_refseq": "Atg2a", "protein_names_uniprotkb": "Autophagy-related protein 2 homolog A isoform X4", "protein_names_refseq": "autophagy-related protein 2 homolog A isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100758391)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.5.5", "type": "external" } ], "go_molecular_function": "GO:0043495 protein-membrane adaptor activity;GO:0032266 phosphatidylinositol-3-phosphate binding", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0034045 phagophore assembly site membrane;GO:0061908 phagophore", "go_biological_process": "GO:0000045 autophagosome assembly;GO:0006869 lipid transport;GO:0000422 autophagy of mitochondrion;GO:0034727 piecemeal microautophagy of the nucleus;GO:0061709 reticulophagy", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FNC8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FMX5-1", "uniprot_id": [ { "id": "A0A9J7FMX5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FMX5", "type": "external" } ], "mass": 57173.0, "length": 525, "protein_name": "Beta-2-syntrophin", "gene_name": "Sntb2", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: beta-2-syntrophin isoform X2", "refseq_ac": [ { "id": "XP_027261735", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261735", "type": "external" } ], "gene_names_uniprotkb": "Sntb2", "gene_names_refseq": "Sntb2", "protein_names_uniprotkb": "Beta-2-syntrophin; 59 kDa dystrophin-associated protein A1 basic component 2; Syntrophin-3; Syntrophin-like", "protein_names_refseq": "LOW QUALITY PROTEIN: beta-2-syntrophin isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754410)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027261735.1. COMPLETENESS: full length., [RefSeq]; Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. May play a role in the regulation of secretory granules via its interaction with PTPRN., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0005516 calmodulin binding;GO:0005198 structural molecule activity", "go_cellular_component": "GO:0016010 dystrophin-associated glycoprotein complex;GO:0005874 microtubule;GO:0045202 synapse;GO:0030658 transport vesicle membrane;GO:0070161 anchoring junction", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FMX5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FMZ5-1", "uniprot_id": [ { "id": "A0A9J7FMZ5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FMZ5", "type": "external" } ], "mass": 61866.0, "length": 553, "protein_name": "Crossover junction endonuclease MUS81", "gene_name": "Mus81", "organism": "Hamster", "refseq_name": "crossover junction endonuclease MUS81 isoform X4", "refseq_ac": [ { "id": "XP_027264399", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264399", "type": "external" } ], "gene_names_uniprotkb": "Mus81", "gene_names_refseq": "Mus81", "protein_names_uniprotkb": "Crossover junction endonuclease MUS81; 3.1.22.-", "protein_names_refseq": "crossover junction endonuclease MUS81 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100770181)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0046872 metal ion binding;GO:0008821 crossover junction DNA endonuclease activity;GO:0048257 3'-flap endonuclease activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0048476 Holliday junction resolvase complex", "go_biological_process": "GO:0000712 resolution of meiotic recombination intermediates;GO:0031573 mitotic intra-S DNA damage checkpoint signaling;GO:0006308 DNA catabolic process;GO:0000727 double-strand break repair via break-induced replication;GO:0031297 replication fork processing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FMZ5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FN46-1", "uniprot_id": [ { "id": "A0A9J7FN46_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FN46", "type": "external" } ], "mass": 224357.0, "length": 2155, "protein_name": "Aggrecan core protein", "gene_name": "Acan", "organism": "Hamster", "refseq_name": "aggrecan core protein isoform X1", "refseq_ac": [ { "id": "XP_027264105", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264105", "type": "external" } ], "gene_names_uniprotkb": "Acan", "gene_names_refseq": "Acan", "protein_names_uniprotkb": "Aggrecan core protein; Cartilage-specific proteoglycan core protein", "protein_names_refseq": "aggrecan core protein isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100764201)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0030246 carbohydrate binding;GO:0005540 hyaluronic acid binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0045202 synapse;GO:0072534 perineuronal net", "go_biological_process": "GO:0007155 cell adhesion;GO:0007417 central nervous system development;GO:0051216 cartilage development;GO:0002052 positive regulation of neuroblast proliferation;GO:0010001 glial cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FN46-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FN55-1", "uniprot_id": [ { "id": "A0A9J7FN55_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FN55", "type": "external" } ], "mass": 149539.0, "length": 1335, "protein_name": "Cyclic nucleotide-gated cation channel beta-1", "gene_name": "Cngb1", "organism": "Hamster", "refseq_name": "cyclic nucleotide-gated cation channel beta-1", "refseq_ac": [ { "id": "XP_027261889", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261889", "type": "external" } ], "gene_names_uniprotkb": "Cngb1", "gene_names_refseq": "Cngb1", "protein_names_uniprotkb": "Cyclic nucleotide-gated cation channel beta-1", "protein_names_refseq": "cyclic nucleotide-gated cation channel beta-1", "tax_id": 10029, "disease": "", "pathway": " (cge:103159708)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 3% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0044877 protein-containing complex binding;GO:0005223 intracellularly cGMP-activated cation channel activity;GO:0005222 intracellularly cAMP-activated cation channel activity;GO:0030553 cGMP binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0001750 photoreceptor outer segment;GO:0017071 intracellular cyclic nucleotide activated cation channel complex", "go_biological_process": "GO:0007601 visual perception;GO:0001895 retina homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FN55-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FN68-1", "uniprot_id": [ { "id": "A0A9J7FN68_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FN68", "type": "external" } ], "mass": 171123.0, "length": 1570, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Mast1", "organism": "Hamster", "refseq_name": "microtubule-associated serine/threonine-protein kinase 1 isoform X2", "refseq_ac": [ { "id": "XP_027262053", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262053", "type": "external" } ], "gene_names_uniprotkb": "Mast1", "gene_names_refseq": "Mast1", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "microtubule-associated serine/threonine-protein kinase 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756729)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0008017 microtubule binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0007010 cytoskeleton organization;GO:0032502 developmental process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FN68-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FNF0-1", "uniprot_id": [ { "id": "A0A9J7FNF0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FNF0", "type": "external" } ], "mass": 92588.0, "length": 830, "protein_name": "Mitogen-activated protein kinase kinase kinase kinase", "gene_name": "Map4k2", "organism": "Hamster", "refseq_name": "mitogen-activated protein kinase kinase kinase kinase 2 isoform X2", "refseq_ac": [ { "id": "XP_027264297", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264297", "type": "external" } ], "gene_names_uniprotkb": "Map4k2", "gene_names_refseq": "Map4k2", "protein_names_uniprotkb": "Mitogen-activated protein kinase kinase kinase kinase; 2.7.11.1", "protein_names_refseq": "mitogen-activated protein kinase kinase kinase kinase 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100761105)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Serine/threonine kinase that plays a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008349 MAP kinase kinase kinase kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FNF0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FPF7-1", "uniprot_id": [ { "id": "A0A9J7FPF7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FPF7", "type": "external" } ], "mass": 40837.0, "length": 357, "protein_name": "Tumor necrosis factor receptor superfamily member 6", "gene_name": "Fas", "organism": "Hamster", "refseq_name": "tumor necrosis factor receptor superfamily member 6 isoform X1", "refseq_ac": [ { "id": "XP_007644632", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644632", "type": "external" } ], "gene_names_uniprotkb": "Fas", "gene_names_refseq": "Fas", "protein_names_uniprotkb": "Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor", "protein_names_refseq": "tumor necrosis factor receptor superfamily member 6 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100762537)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614200.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005031 tumor necrosis factor receptor activity", "go_cellular_component": "GO:0045121 membrane raft;GO:0009897 external side of plasma membrane;GO:0031265 CD95 death-inducing signaling complex", "go_biological_process": "GO:0006955 immune response;GO:0043066 negative regulation of apoptotic process;GO:0009636 response to toxic substance;GO:0006924 activation-induced cell death of T cells;GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FPF7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FNK1-1", "uniprot_id": [ { "id": "A0A9J7FNK1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FNK1", "type": "external" } ], "mass": 31195.0, "length": 274, "protein_name": "N-alpha-acetyltransferase 40", "gene_name": "Naa40", "organism": "Hamster", "refseq_name": "N-alpha-acetyltransferase 40 isoform X3", "refseq_ac": [ { "id": "XP_027264213", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264213", "type": "external" } ], "gene_names_uniprotkb": "Naa40", "gene_names_refseq": "Naa40", "protein_names_uniprotkb": "N-alpha-acetyltransferase 40; 2.3.1.257; N-acetyltransferase 11; N-alpha-acetyltransferase D; Protein acetyltransferase 1", "protein_names_refseq": "N-alpha-acetyltransferase 40 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100754917)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; N-alpha-acetyltransferase that specifically mediates the acetylation of the N-terminal residues of histones H4 and H2A. In contrast to other N-alpha-acetyltransferase, has a very specific selectivity for histones H4 and H2A N-terminus and specifically recognizes the 'Ser-Gly-Arg-Gly sequence'. Acts as a negative regulator of apoptosis. May play a role in hepatic lipid metabolism., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.257", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.257", "type": "external" } ], "go_molecular_function": "GO:0010485 histone H4 acetyltransferase activity;GO:0043998 histone H2A acetyltransferase activity;GO:1990189 protein N-terminal-serine acetyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FNK1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FRK2-1", "uniprot_id": [ { "id": "A0A9J7FRK2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FRK2", "type": "external" } ], "mass": 90476.0, "length": 826, "protein_name": "Disintegrin and metalloproteinase domain-containing protein 8 isoform X1", "gene_name": "Adam8", "organism": "Hamster", "refseq_name": "disintegrin and metalloproteinase domain-containing protein 8 isoform X1", "refseq_ac": [ { "id": "XP_027264860", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264860", "type": "external" } ], "gene_names_uniprotkb": "Adam8", "gene_names_refseq": "Adam8", "protein_names_uniprotkb": "Disintegrin and metalloproteinase domain-containing protein 8 isoform X1", "protein_names_refseq": "disintegrin and metalloproteinase domain-containing protein 8 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100770949)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding;GO:0050839 cell adhesion molecule binding", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0006954 inflammatory response;GO:0051044 positive regulation of membrane protein ectodomain proteolysis;GO:0022407 regulation of cell-cell adhesion;GO:0002693 positive regulation of cellular extravasation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FRK2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FNN8-1", "uniprot_id": [ { "id": "A0A9J7FNN8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FNN8", "type": "external" } ], "mass": 81770.0, "length": 764, "protein_name": "Endosialin", "gene_name": "Cd248", "organism": "Hamster", "refseq_name": "endosialin isoform X2", "refseq_ac": [ { "id": "XP_027264439", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264439", "type": "external" } ], "gene_names_uniprotkb": "Cd248", "gene_names_refseq": "Cd248", "protein_names_uniprotkb": "Endosialin; Tumor endothelial marker 1", "protein_names_refseq": "endosialin isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100768169)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:1990430 extracellular matrix protein binding;GO:0005509 calcium ion binding;GO:0030246 carbohydrate binding;GO:0050840 extracellular matrix binding", "go_cellular_component": "GO:0031012 extracellular matrix;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0016477 cell migration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FNN8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FR72-1", "uniprot_id": [ { "id": "A0A9J7FR72_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FR72", "type": "external" } ], "mass": 25532.0, "length": 222, "protein_name": "Glutathione S-transferase", "gene_name": "LOC100757534", "organism": "Hamster", "refseq_name": "glutathione S-transferase P 2 isoform X2", "refseq_ac": [ { "id": "XP_003509973", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509973", "type": "external" } ], "gene_names_uniprotkb": "LOC100757534", "gene_names_refseq": "LOC100757534", "protein_names_uniprotkb": "Glutathione S-transferase; 2.5.1.18; GST class-pi", "protein_names_refseq": "glutathione S-transferase P 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100757534)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614797.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003509973.1. COMPLETENESS: full length., [RefSeq]; Catalyzes conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. Acts as a negative regulator of ferroptosis by mediating glutathione conjugation and detoxification of 4-hydroxynonenal (4-HNE) reactive aldehyde. Negatively regulates CDK5 activity via p25/p35 translocation to prevent neurodegeneration., [UniProtKB, UniProtKB]; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.5.1.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.18", "type": "external" }, { "id": "5.2.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.2", "type": "external" }, { "id": "5.3.99.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.99.2", "type": "external" }, { "id": "1.20.4.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.20.4.2", "type": "external" }, { "id": "1.8.5.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.5.1", "type": "external" }, { "id": "1.11.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.-", "type": "external" }, { "id": "4.4.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:4.4.1.20", "type": "external" } ], "go_molecular_function": "GO:0004364 glutathione transferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0006749 glutathione metabolic process;GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FR72-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FNS4-1", "uniprot_id": [ { "id": "A0A9J7FNS4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FNS4", "type": "external" } ], "mass": 63767.0, "length": 576, "protein_name": "E3 ubiquitin-protein ligase ZFP91", "gene_name": "Zfp91", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase ZFP91 isoform X3", "refseq_ac": [ { "id": "XP_027262396", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262396", "type": "external" } ], "gene_names_uniprotkb": "Zfp91", "gene_names_refseq": "Zfp91", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase ZFP91; 2.3.2.27; RING-type E3 ubiquitin transferase ZFP91; Zinc finger protein 91 homolog", "protein_names_refseq": "LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase ZFP91 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100751041)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 3 indels ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; DNA-binding transcription factor. Also acts as an atypical E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked ubiquitination of MAP3K14/NIK, leading to stabilize and activate MAP3K14/NIK. It thereby acts as an activator of the non-canonical NF-kappa-B2/NFKB2 pathway. May also play an important role in cell proliferation and/or anti-apoptosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FNS4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FTU9-1", "uniprot_id": [ { "id": "A0A9J7FTU9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FTU9", "type": "external" } ], "mass": 55129.0, "length": 503, "protein_name": "Peroxisomal N(1)-acetyl-spermine/spermidine oxidase", "gene_name": "Paox", "organism": "Hamster", "refseq_name": "peroxisomal N(1)-acetyl-spermine/spermidine oxidase isoform X2", "refseq_ac": [ { "id": "XP_027264850", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264850", "type": "external" } ], "gene_names_uniprotkb": "Paox", "gene_names_refseq": "Paox", "protein_names_uniprotkb": "Peroxisomal N(1)-acetyl-spermine/spermidine oxidase; 1.5.3.13; Polyamine oxidase", "protein_names_refseq": "peroxisomal N(1)-acetyl-spermine/spermidine oxidase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754371)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.5.3.13", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.3.13", "type": "external" } ], "go_molecular_function": "GO:0046592 polyamine oxidase activity;GO:0052903 N(1)-acetylpolyamine oxidase (3-acetamidopropanal-forming) activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005777 peroxisome", "go_biological_process": "GO:0046203 spermidine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FTU9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FPD4-1", "uniprot_id": [ { "id": "A0A9J7FPD4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FPD4", "type": "external" } ], "mass": 126998.0, "length": 1166, "protein_name": "Poly [ADP-ribose] polymerase", "gene_name": "Tnks2", "organism": "Hamster", "refseq_name": "poly [ADP-ribose] polymerase tankyrase-2 isoform X2", "refseq_ac": [ { "id": "XP_027262137", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262137", "type": "external" } ], "gene_names_uniprotkb": "Tnks2", "gene_names_refseq": "Tnks2", "protein_names_uniprotkb": "Poly [ADP-ribose] polymerase; 2.4.2.-; PARP", "protein_names_refseq": "poly [ADP-ribose] polymerase tankyrase-2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100769660)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0016779 nucleotidyltransferase activity;GO:0003950 NAD+ poly-ADP-ribosyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005634 nucleus;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0016055 Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FPD4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FPH2-1", "uniprot_id": [ { "id": "A0A9J7FPH2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FPH2", "type": "external" } ], "mass": 72427.0, "length": 669, "protein_name": "Leucine zipper putative tumor suppressor 2", "gene_name": "Lzts2", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: leucine zipper putative tumor suppressor 2 isoform X2", "refseq_ac": [ { "id": "XP_027263001", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263001", "type": "external" } ], "gene_names_uniprotkb": "Lzts2; LAPSER1; LZTS2", "gene_names_refseq": "Lzts2", "protein_names_uniprotkb": "Leucine zipper putative tumor suppressor 2; Protein LAPSER1", "protein_names_refseq": "LOW QUALITY PROTEIN: leucine zipper putative tumor suppressor 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100757480)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005874 microtubule;GO:0030496 midbody", "go_biological_process": "GO:0051013 microtubule severing;GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0016055 Wnt signaling pathway;GO:0000281 mitotic cytokinesis;GO:0051168 nuclear export", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FPH2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FPH3-1", "uniprot_id": [ { "id": "A0A9J7FPH3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FPH3", "type": "external" } ], "mass": 87707.0, "length": 767, "protein_name": "Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2", "gene_name": "Cmtr2", "organism": "Hamster", "refseq_name": "cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2", "refseq_ac": [ { "id": "XP_027261795", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261795", "type": "external" } ], "gene_names_uniprotkb": "Cmtr2", "gene_names_refseq": "Cmtr2", "protein_names_uniprotkb": "Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2; 2.1.1.296; Cap methyltransferase 2; Cap2 2'O-ribose methyltransferase 2; FtsJ methyltransferase domain-containing protein 1", "protein_names_refseq": "cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754099)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap2 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the second nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) (cap0) to produce m(7)GpppRmpNm (cap2). Recognizes a guanosine cap on RNA independently of its N(7) methylation status. Display cap2 methylation on both cap0 and cap1. Displays a preference for cap1 RNAs., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.296", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.296", "type": "external" } ], "go_molecular_function": "GO:0004483 methyltransferase cap1 activity;GO:0120550 methyltransferase cap2 activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0032259 methylation;GO:0006370 7-methylguanosine mRNA capping", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FPH3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FPH6-1", "uniprot_id": [ { "id": "A0A9J7FPH6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FPH6", "type": "external" } ], "mass": 37786.0, "length": 340, "protein_name": "Ankyrin repeat domain-containing protein 2", "gene_name": "Ankrd2", "organism": "Hamster", "refseq_name": "ankyrin repeat domain-containing protein 2", "refseq_ac": [ { "id": "XP_016823032", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016823032", "type": "external" } ], "gene_names_uniprotkb": "Ankrd2", "gene_names_refseq": "Ankrd2", "protein_names_uniprotkb": "Ankyrin repeat domain-containing protein 2; Skeletal muscle ankyrin repeat protein", "protein_names_refseq": "ankyrin repeat domain-containing protein 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100758530)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613664.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Dec 18, 2018 this sequence version replaced XP_016823032.1. COMPLETENESS: full length., [RefSeq]; Functions as a negative regulator of myocyte differentiation. May interact with both sarcoplasmic structural proteins and nuclear proteins to regulate gene expression during muscle development and in response to muscle stress., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043422 protein kinase B binding;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005829 cytosol;GO:0031674 I band;GO:0016605 PML body", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0035994 response to muscle stretch;GO:0045662 negative regulation of myoblast differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FPH6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FPK3-1", "uniprot_id": [ { "id": "A0A9J7FPK3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FPK3", "type": "external" } ], "mass": 77134.0, "length": 686, "protein_name": "Twinkle mtDNA helicase", "gene_name": "Twnk", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: twinkle protein, mitochondrial", "refseq_ac": [ { "id": "XP_027263000", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263000", "type": "external" } ], "gene_names_uniprotkb": "Twnk", "gene_names_refseq": "Twnk", "protein_names_uniprotkb": "Twinkle mtDNA helicase; 5.6.2.3; T7 gp4-like protein with intramitochondrial nucleoid localization; T7-like mitochondrial DNA helicase; Twinkle protein, mitochondrial", "protein_names_refseq": "LOW QUALITY PROTEIN: twinkle protein, mitochondrial", "tax_id": 10029, "disease": "", "pathway": " (cge:100756896)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Mitochondrial helicase involved in mtDNA replication and repair. Might have a role in mtDNA repair. Has DNA strand separation activity needed to form a processive replication fork for leading strand synthesis which is catalyzed by the formation of a replisome complex with POLG and mtSDB. Preferentially unwinds DNA substrates with pre-existing 5'-and 3'- single-stranded tails but is also active on a 5'- flap substrate. Can dissociate the invading strand of immobile or mobile D-loop DNA structures irrespective of the single strand polarity of the third strand. In addition to its DNA strand separation activity, also has DNA strand annealing, DNA strand-exchange and DNA branch migration activities., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0008289 lipid binding;GO:0003697 single-stranded DNA binding;GO:0043139 5'-3' DNA helicase activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0042645 mitochondrial nucleoid", "go_biological_process": "GO:0006264 mitochondrial DNA replication", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FPK3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FPW3-1", "uniprot_id": [ { "id": "A0A9J7FPW3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FPW3", "type": "external" } ], "mass": 68793.0, "length": 615, "protein_name": "Prolyl 4-hydroxylase subunit alpha-3", "gene_name": "P4ha3", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: prolyl 4-hydroxylase subunit alpha-3 isoform X4", "refseq_ac": [ { "id": "XP_027263298", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263298", "type": "external" } ], "gene_names_uniprotkb": "P4ha3", "gene_names_refseq": "P4ha3", "protein_names_uniprotkb": "Prolyl 4-hydroxylase subunit alpha-3; 1.14.11.2; Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3", "protein_names_refseq": "LOW QUALITY PROTEIN: prolyl 4-hydroxylase subunit alpha-3 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100766769)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 10% of CDS bases frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.2", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0031418 L-ascorbic acid binding;GO:0004656 procollagen-proline 4-dioxygenase activity", "go_cellular_component": "GO:0005788 endoplasmic reticulum lumen", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FPW3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FPX9-1", "uniprot_id": [ { "id": "A0A9J7FPX9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FPX9", "type": "external" } ], "mass": 250979.0, "length": 2177, "protein_name": "Unconventional myosin-VIIa", "gene_name": "Myo7a", "organism": "Hamster", "refseq_name": "unconventional myosin-VIIa", "refseq_ac": [ { "id": "XP_027263507", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263507", "type": "external" } ], "gene_names_uniprotkb": "Myo7a", "gene_names_refseq": "Myo7a", "protein_names_uniprotkb": "Unconventional myosin-VIIa", "protein_names_refseq": "unconventional myosin-VIIa", "tax_id": 10029, "disease": "", "pathway": " (cge:100768082)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0003774 cytoskeletal motor activity", "go_cellular_component": "GO:0097733 photoreceptor cell cilium;GO:0005938 cell cortex;GO:0016020 membrane;GO:0045177 apical part of cell;GO:0045202 synapse", "go_biological_process": "GO:0007601 visual perception;GO:0007040 lysosome organization;GO:0007605 sensory perception of sound;GO:0048666 neuron development;GO:0090596 sensory organ morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FPX9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FQ43-1", "uniprot_id": [ { "id": "A0A9J7FQ43_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FQ43", "type": "external" } ], "mass": 197580.0, "length": 1816, "protein_name": "Nuclear pore complex protein Nup98-Nup96", "gene_name": "Nup98", "organism": "Hamster", "refseq_name": "nuclear pore complex protein Nup98-Nup96 isoform X1", "refseq_ac": [ { "id": "XP_003509754", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509754", "type": "external" } ], "gene_names_uniprotkb": "Nup98", "gene_names_refseq": "Nup98", "protein_names_uniprotkb": "Nuclear pore complex protein Nup98-Nup96", "protein_names_refseq": "nuclear pore complex protein Nup98-Nup96 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100760516)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614758.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. NUP98 and NUP96 are involved in the bidirectional transport across the NPC. May anchor NUP153 and TPR to the NPC. In cooperation with DHX9, plays a role in transcription and alternative splicing activation of a subset of genes. Involved in the localization of DHX9 in discrete intranuclear foci (GLFG-body)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0017056 structural constituent of nuclear pore;GO:0008139 nuclear localization sequence binding;GO:0008236 serine-type peptidase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0031965 nuclear membrane;GO:0044614 nuclear pore cytoplasmic filaments", "go_biological_process": "GO:0006508 proteolysis;GO:0051028 mRNA transport;GO:0000973 post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery;GO:0034398 telomere tethering at nuclear periphery;GO:0006405 RNA export from nucleus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FQ43-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FQ53-1", "uniprot_id": [ { "id": "A0A9J7FQ53_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FQ53", "type": "external" } ], "mass": 170997.0, "length": 1521, "protein_name": "DNA excision repair protein ERCC-6-like 2", "gene_name": "Ercc6l2", "organism": "Hamster", "refseq_name": "DNA excision repair protein ERCC-6-like 2 isoform X3", "refseq_ac": [ { "id": "XP_027265456", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265456", "type": "external" } ], "gene_names_uniprotkb": "Ercc6l2", "gene_names_refseq": "Ercc6l2", "protein_names_uniprotkb": "DNA excision repair protein ERCC-6-like 2; DNA repair and recombination protein RAD26-like", "protein_names_refseq": "DNA excision repair protein ERCC-6-like 2 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100751043)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Promotes double-strand break (DSB) end-joining and facilitates programmed recombination by controlling how DNA ends are joined in a spatially oriented manner during repair. Also plays a role in DNA repair by restricting DNA end resection in double strand break (DSB) repair. Facilitates replication of complex DNA regions and regulates the maintenance of chromatin structure., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0004386 helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005813 centrosome;GO:0000775 chromosome, centromeric region", "go_biological_process": "GO:0097680 double-strand break repair via classical nonhomologous end joining", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FQ53-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FSV5-1", "uniprot_id": [ { "id": "A0A9J7FSV5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FSV5", "type": "external" } ], "mass": 295329.0, "length": 2690, "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "gene_name": "Nsd1", "organism": "Hamster", "refseq_name": "histone-lysine N-methyltransferase, H3 lysine-36 specific isoform X1", "refseq_ac": [ { "id": "XP_027265605", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265605", "type": "external" } ], "gene_names_uniprotkb": "Nsd1", "gene_names_refseq": "Nsd1", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase, H3 lysine-36 specific; 2.1.1.357; H3-K36-HMTase; Nuclear receptor-binding SET domain-containing protein 1", "protein_names_refseq": "histone-lysine N-methyltransferase, H3 lysine-36 specific isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100773206)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.357", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.357", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003712 transcription coregulator activity;GO:0016922 nuclear receptor binding;GO:0140954 histone H3K36 dimethyltransferase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005694 chromosome", "go_biological_process": "GO:0045892 negative regulation of DNA-templated transcription;GO:0032259 methylation;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FSV5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FQS8-1", "uniprot_id": [ { "id": "A0A9J7FQS8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FQS8", "type": "external" } ], "mass": 88343.0, "length": 791, "protein_name": "Actin filament-associated protein 1-like 2", "gene_name": "Afap1l2", "organism": "Hamster", "refseq_name": "actin filament-associated protein 1-like 2 isoform X2", "refseq_ac": [ { "id": "XP_027262714", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262714", "type": "external" } ], "gene_names_uniprotkb": "Afap1l2", "gene_names_refseq": "Afap1l2", "protein_names_uniprotkb": "Actin filament-associated protein 1-like 2", "protein_names_refseq": "actin filament-associated protein 1-like 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100771462)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017124 SH3 domain binding;GO:0042169 SH2 domain binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006954 inflammatory response;GO:0007346 regulation of mitotic cell cycle;GO:0032675 regulation of interleukin-6 production;GO:0045893 positive regulation of DNA-templated transcription;GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FQS8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FR93-1", "uniprot_id": [ { "id": "A0A9J7FR93_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FR93", "type": "external" } ], "mass": 128579.0, "length": 1177, "protein_name": "Protein transport protein Sec31A", "gene_name": "Sec31b", "organism": "Hamster", "refseq_name": "protein transport protein Sec31B", "refseq_ac": [ { "id": "XP_003508488", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508488", "type": "external" } ], "gene_names_uniprotkb": "Sec31b", "gene_names_refseq": "Sec31b", "protein_names_uniprotkb": "Protein transport protein Sec31A; SEC31-like protein 1; SEC31-related protein A", "protein_names_refseq": "protein transport protein Sec31B", "tax_id": 10029, "disease": "", "pathway": " (cge:100774608)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614544.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0070971 endoplasmic reticulum exit site;GO:0030127 COPII vesicle coat", "go_biological_process": "GO:0090110 COPII-coated vesicle cargo loading;GO:0015031 protein transport;GO:0007029 endoplasmic reticulum organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FR93-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FRE8-1", "uniprot_id": [ { "id": "A0A9J7FRE8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FRE8", "type": "external" } ], "mass": 84163.0, "length": 739, "protein_name": "F-BAR and double SH3 domains protein 2", "gene_name": "Fchsd2", "organism": "Hamster", "refseq_name": "F-BAR and double SH3 domains protein 2 isoform X1", "refseq_ac": [ { "id": "XP_003508629", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508629", "type": "external" } ], "gene_names_uniprotkb": "Fchsd2", "gene_names_refseq": "Fchsd2", "protein_names_uniprotkb": "F-BAR and double SH3 domains protein 2; Protein nervous wreck 1; SH3 multiple domains protein 3", "protein_names_refseq": "F-BAR and double SH3 domains protein 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100773820)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 177 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614557.1) and transcript sequence (IACG01088131.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Adapter protein that plays a role in endocytosis via clathrin-coated pits. Contributes to the internalization of cell surface receptors, such as integrin ITGB1 and transferrin receptor. Promotes endocytosis of EGFR in cancer cells, and thereby contributes to the down-regulation of EGFR signaling. Recruited to clathrin-coated pits during a mid-to-late stage of assembly, where it is required for normal progress from U-shaped intermediate stage pits to terminal, omega-shaped pits. Binds to membranes enriched in phosphatidylinositol 3,4-bisphosphate or phosphatidylinositol 3,4,5-trisphosphate. When bound to membranes, promotes actin polymerization via its interaction with WAS and/or WASL which leads to the activation of the Arp2/3 complex. Does not promote actin polymerisation in the absence of membranes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008289 lipid binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005905 clathrin-coated pit;GO:0031594 neuromuscular junction;GO:0055037 recycling endosome;GO:0032420 stereocilium", "go_biological_process": "GO:0006897 endocytosis;GO:0007274 neuromuscular synaptic transmission;GO:0015031 protein transport;GO:0030838 positive regulation of actin filament polymerization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FRE8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FRM5-1", "uniprot_id": [ { "id": "A0A9J7FRM5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FRM5", "type": "external" } ], "mass": 505291.0, "length": 4587, "protein_name": "Protocadherin Fat 3", "gene_name": "Fat3", "organism": "Hamster", "refseq_name": "protocadherin Fat 3 isoform X1", "refseq_ac": [ { "id": "XP_027266684", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266684", "type": "external" } ], "gene_names_uniprotkb": "Fat3", "gene_names_refseq": "Fat3", "protein_names_uniprotkb": "Protocadherin Fat 3; FAT tumor suppressor homolog 3", "protein_names_refseq": "protocadherin Fat 3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:113835159)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027266684.1. COMPLETENESS: full length., [RefSeq]; May play a role in the interactions between neurites derived from specific subsets of neurons during development., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043005 neuron projection;GO:0005911 cell-cell junction", "go_biological_process": "GO:0016358 dendrite development;GO:0001764 neuron migration;GO:0009887 animal organ morphogenesis;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0048646 anatomical structure formation involved in morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FRM5-1", "record_type": "protein", "filter_code": "0000000.0000101.000100.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FRT3-1", "uniprot_id": [ { "id": "A0A9J7FRT3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FRT3", "type": "external" } ], "mass": 36699.0, "length": 322, "protein_name": "Poly [ADP-ribose] polymerase", "gene_name": "Parp16", "organism": "Hamster", "refseq_name": "protein mono-ADP-ribosyltransferase PARP16 isoform X1", "refseq_ac": [ { "id": "XP_027267137", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267137", "type": "external" } ], "gene_names_uniprotkb": "Parp16", "gene_names_refseq": "Parp16", "protein_names_uniprotkb": "Poly [ADP-ribose] polymerase; 2.4.2.-; PARP", "protein_names_refseq": "protein mono-ADP-ribosyltransferase PARP16 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100753348)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Intracellular mono-ADP-ribosyltransferase that plays a role in different processes, such as protein translation and unfolded protein response (UPR), through the mono-ADP-ribosylation of proteins involved in those processes. Acts as an inhibitor of protein translation by catalyzing mono-ADP-ribosylation of ribosomal subunits, such as RPL14 and RPS6, thereby inhibiting polysome assembly and mRNA loading. Mono-ADP-ribosylation of ribosomal subunits is promoted by NMNAT2. Involved in the unfolded protein response (UPR) by ADP-ribosylating and activating EIF2AK3 and ERN1, two important UPR effectors. May also mediate mono-ADP-ribosylation of karyopherin KPNB1 a nuclear import factor. May not modify proteins on arginine or cysteine residues compared to other mono-ADP-ribosyltransferases., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.-", "type": "external" }, { "id": "2.3.1.286", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.286", "type": "external" }, { "id": "2.4.2.30", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.30", "type": "external" } ], "go_molecular_function": "GO:0016779 nucleotidyltransferase activity;GO:0003950 NAD+ poly-ADP-ribosyltransferase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006986 response to unfolded protein", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FRT3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FU87-1", "uniprot_id": [ { "id": "A0A9J7FU87_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FU87", "type": "external" } ], "mass": 128991.0, "length": 1177, "protein_name": "Sodium/potassium/calcium exchanger 1", "gene_name": "Slc24a1", "organism": "Hamster", "refseq_name": "sodium/potassium/calcium exchanger 1 isoform X6", "refseq_ac": [ { "id": "XP_027267157", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267157", "type": "external" } ], "gene_names_uniprotkb": "Slc24a1", "gene_names_refseq": "Slc24a1", "protein_names_uniprotkb": "Sodium/potassium/calcium exchanger 1; Na(+)/K(+)/Ca(2+)-exchange protein 1; Retinal rod Na-Ca+K exchanger; Solute carrier family 24 member 1", "protein_names_refseq": "sodium/potassium/calcium exchanger 1 isoform X6", "tax_id": 10029, "disease": "", "pathway": " (cge:100773154)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005262 calcium channel activity;GO:0015293 symporter activity;GO:0008273 calcium, potassium:sodium antiporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006874 intracellular calcium ion homeostasis;GO:0060292 long-term synaptic depression;GO:0007601 visual perception;GO:0060291 long-term synaptic potentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FU87-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FRV2-1", "uniprot_id": [ { "id": "A0A9J7FRV2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FRV2", "type": "external" } ], "mass": 21502.0, "length": 183, "protein_name": "Bcl-2-like protein 10", "gene_name": "Bcl2l10", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: bcl-2-like protein 10", "refseq_ac": [ { "id": "XP_003495102", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495102", "type": "external" } ], "gene_names_uniprotkb": "Bcl2l10", "gene_names_refseq": "Bcl2l10", "protein_names_uniprotkb": "Bcl-2-like protein 10; Anti-apoptotic protein Boo; Apoptosis regulator Bcl-B", "protein_names_refseq": "LOW QUALITY PROTEIN: bcl-2-like protein 10", "tax_id": 10029, "disease": "", "pathway": " (cge:100752860)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613582.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Promotes cell survival by suppressing apoptosis induced by BAX but not BAK. Increases binding of AHCYL1/IRBIT to ITPR1. Reduces ITPR1-mediated calcium release from the endoplasmic reticulum cooperatively with AHCYL1/IRBIT under normal cellular conditions. Under apoptotic stress conditions, dissociates from ITPR1 and is displaced from mitochondria-associated endoplasmic reticulum membranes, leading to increased Ca(2+) transfer to mitochondria which promotes apoptosis. Required for the correct formation of the microtubule organizing center during oocyte cell division, potentially via regulation of protein abundance and localization of other microtubule organizing center components such as AURKA and TPX2., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051400 BH domain binding", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005783 endoplasmic reticulum;GO:0005819 spindle;GO:0031965 nuclear membrane", "go_biological_process": "GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage;GO:0001836 release of cytochrome c from mitochondria;GO:0042981 regulation of apoptotic process;GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FRV2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FS04-1", "uniprot_id": [ { "id": "A0A9J7FS04_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FS04", "type": "external" } ], "mass": 57887.0, "length": 530, "protein_name": "Sulfotransferase", "gene_name": "Chst2", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: carbohydrate sulfotransferase 2 isoform X2", "refseq_ac": [ { "id": "XP_027266741", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266741", "type": "external" } ], "gene_names_uniprotkb": "Chst2", "gene_names_refseq": "Chst2", "protein_names_uniprotkb": "Sulfotransferase; 2.8.2.-", "protein_names_refseq": "LOW QUALITY PROTEIN: carbohydrate sulfotransferase 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767419)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.8.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.2.-", "type": "external" } ], "go_molecular_function": "GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0006044 N-acetylglucosamine metabolic process;GO:0006954 inflammatory response;GO:0005975 carbohydrate metabolic process;GO:0006790 sulfur compound metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FS04-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FS48-1", "uniprot_id": [ { "id": "A0A9J7FS48_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FS48", "type": "external" } ], "mass": 108525.0, "length": 1023, "protein_name": "Zinc finger protein ZFPM1", "gene_name": "Zfpm1", "organism": "Hamster", "refseq_name": "zinc finger protein ZFPM1 isoform X2", "refseq_ac": [ { "id": "XP_027266477", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266477", "type": "external" } ], "gene_names_uniprotkb": "Zfpm1", "gene_names_refseq": "Zfpm1", "protein_names_uniprotkb": "Zinc finger protein ZFPM1; Friend of GATA protein 1; Zinc finger protein multitype 1", "protein_names_refseq": "zinc finger protein ZFPM1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754845)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. May be involved in regulation of some genes in gonads. May also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0003714 transcription corepressor activity;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0030219 megakaryocyte differentiation;GO:0003192 mitral valve formation;GO:0003195 tricuspid valve formation;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FS48-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FS53-1", "uniprot_id": [ { "id": "A0A9J7FS53_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FS53", "type": "external" } ], "mass": 96452.0, "length": 852, "protein_name": "Dual specificity protein kinase TTK", "gene_name": "Ttk", "organism": "Hamster", "refseq_name": "dual specificity protein kinase TTK isoform X1", "refseq_ac": [ { "id": "XP_007638910", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638910", "type": "external" } ], "gene_names_uniprotkb": "Ttk", "gene_names_refseq": "Ttk", "protein_names_uniprotkb": "Dual specificity protein kinase TTK; 2.7.12.1", "protein_names_refseq": "dual specificity protein kinase TTK isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100774563)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 141 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613765.1) and transcript sequence (JI876735.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in mitotic spindle assembly checkpoint signaling, a process that delays anaphase until chromosomes are bioriented on the spindle, and in the repair of incorrect mitotic kinetochore-spindle microtubule attachments. Phosphorylates MAD1L1 to promote the mitotic spindle assembly checkpoint. Phosphorylates CDCA8/Borealin leading to enhanced AURKB activity at the kinetochore. Phosphorylates SKA3 at 'Ser-34' leading to dissociation of the SKA complex from microtubules and destabilization of microtubule-kinetochore attachments. Phosphorylates KNL1, KNTC1 and autophosphorylates. Phosphorylates MCRS1 which enhances recruitment of KIF2A to the minus end of spindle microtubules and promotes chromosome alignment., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0004712 protein serine/threonine/tyrosine kinase activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000776 kinetochore;GO:0005737 cytoplasm", "go_biological_process": "GO:0033316 meiotic spindle assembly checkpoint signaling;GO:0007094 mitotic spindle assembly checkpoint signaling;GO:0034501 protein localization to kinetochore;GO:0098813 nuclear chromosome segregation;GO:0000280 nuclear division", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FS53-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FSC8-1", "uniprot_id": [ { "id": "A0A9J7FSC8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FSC8", "type": "external" } ], "mass": 49342.0, "length": 449, "protein_name": "Succinyl-CoA:glutarate CoA-transferase", "gene_name": "Sugct", "organism": "Hamster", "refseq_name": "succinate--hydroxymethylglutarate CoA-transferase isoform X3", "refseq_ac": [ { "id": "XP_007646544", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646544", "type": "external" } ], "gene_names_uniprotkb": "Sugct", "gene_names_refseq": "Sugct", "protein_names_uniprotkb": "Succinyl-CoA:glutarate CoA-transferase; 2.8.3.13; Dicarboxyl-CoA:dicarboxylic acid coenzyme A transferase SUGCT; Succinate--hydroxymethylglutarate CoA-transferase", "protein_names_refseq": "succinate--hydroxymethylglutarate CoA-transferase isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100770206)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613616.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Coenzyme A (CoA) transferase that reversibly catalyzes the transfer of a CoA moiety from a dicarboxyl-CoA to a dicarboxylate in a metabolite recycling process. Displays preference for succinyl-CoA and glutarate-CoA as dicarboxyl-CoA donors and glutarate, succinate, adipate/hexanedioate, itaconate and 3-hydroxy-3-methylglutarate as dicarboxylate acceptors. Acts on intermediates or end products of lysine and tryptophan degradation pathway, in particular catalyzes succinyl-CoA-dependent reesterification of free glutarate into glutaryl-CoA to prevent renal excretion of glutarate. Upon inflammation, may convert macrophage-derived itaconate to itaconyl-CoA in erythroid precursors where it negatively regulates the TCA cycle and heme synthesis to limit erythroid differentiation in the context of stress erythropoiesis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.8.3.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.3.13", "type": "external" } ], "go_molecular_function": "GO:0047369 succinate-hydroxymethylglutarate CoA-transferase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FSC8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FSD9-1", "uniprot_id": [ { "id": "A0A9J7FSD9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FSD9", "type": "external" } ], "mass": 66565.0, "length": 606, "protein_name": "Coagulation factor XII", "gene_name": "F12", "organism": "Hamster", "refseq_name": "coagulation factor XII isoform X2", "refseq_ac": [ { "id": "XP_027265597", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265597", "type": "external" } ], "gene_names_uniprotkb": "F12", "gene_names_refseq": "F12", "protein_names_uniprotkb": "Coagulation factor XII; 3.4.21.38; Hageman factor", "protein_names_refseq": "coagulation factor XII isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100764143)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005791 rough endoplasmic reticulum", "go_biological_process": "GO:0007596 blood coagulation;GO:0042730 fibrinolysis;GO:0031638 zymogen activation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FSD9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FSE3-1", "uniprot_id": [ { "id": "A0A9J7FSE3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FSE3", "type": "external" } ], "mass": 96740.0, "length": 872, "protein_name": "matriptase", "gene_name": "St14", "organism": "Hamster", "refseq_name": "suppressor of tumorigenicity 14 protein isoform X1", "refseq_ac": [ { "id": "XP_027267542", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267542", "type": "external" } ], "gene_names_uniprotkb": "St14", "gene_names_refseq": "St14", "protein_names_uniprotkb": "matriptase; 3.4.21.109; Serine protease 14", "protein_names_refseq": "suppressor of tumorigenicity 14 protein isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100755225)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site. Involved in the terminal differentiation of keratinocytes through prostasin (PRSS8) activation and filaggrin (FLG) processing. Proteolytically cleaves and therefore activates TMPRSS13., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0030855 epithelial cell differentiation;GO:0048513 animal organ development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FSE3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FSG4-1", "uniprot_id": [ { "id": "A0A9J7FSG4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FSG4", "type": "external" } ], "mass": 42392.0, "length": 377, "protein_name": "Pseudouridylate synthase RPUSD4, mitochondrial", "gene_name": "Rpusd4", "organism": "Hamster", "refseq_name": "mitochondrial RNA pseudouridine synthase RPUSD4", "refseq_ac": [ { "id": "XP_027267585", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267585", "type": "external" } ], "gene_names_uniprotkb": "Rpusd4", "gene_names_refseq": "Rpusd4", "protein_names_uniprotkb": "Pseudouridylate synthase RPUSD4, mitochondrial; RNA pseudouridylate synthase domain-containing protein 4", "protein_names_refseq": "mitochondrial RNA pseudouridine synthase RPUSD4", "tax_id": 10029, "disease": "", "pathway": " (cge:100758848)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes uridine to pseudouridine isomerization (pseudouridylation) of different mitochondrial RNA substrates. Acts on position 1397 in 16S mitochondrial ribosomal RNA (16S mt-rRNA). This modification is required for the assembly of 16S mt-rRNA into a functional mitochondrial ribosome. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA, controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation. Acts on position 39 in mitochondrial tRNA(Phe). Also catalyzes pseudouridylation of mRNAs in nucleus: acts as a regulator of pre-mRNA splicing by mediating pseudouridylation of pre-mRNAs at locations associated with alternatively spliced regions. Pseudouridylation of pre-mRNAs near splice sites directly regulates mRNA splicing and mRNA 3'-end processing., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.4.99.12", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.99.12", "type": "external" }, { "id": "5.4.99.25", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.99.25", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0009982 pseudouridine synthase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0008033 tRNA processing;GO:0006364 rRNA processing;GO:0001522 pseudouridine synthesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FSG4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FWX7-1", "uniprot_id": [ { "id": "A0A9J7FWX7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FWX7", "type": "external" } ], "mass": 71533.0, "length": 638, "protein_name": "Ubiquitin-associated and SH3 domain-containing protein B", "gene_name": "LOC103158664", "organism": "Hamster", "refseq_name": "ubiquitin-associated and SH3 domain-containing protein B isoform X3", "refseq_ac": [ { "id": "XP_027267674", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267674", "type": "external" } ], "gene_names_uniprotkb": "LOC103158664", "gene_names_refseq": "LOC103158664", "protein_names_uniprotkb": "Ubiquitin-associated and SH3 domain-containing protein B; 3.1.3.48; Cbl-interacting protein p70; Suppressor of T-cell receptor signaling 1; T-cell ubiquitin ligand 2; Tyrosine-protein phosphatase STS1/TULA2", "protein_names_refseq": "ubiquitin-associated and SH3 domain-containing protein B isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:103158664)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" } ], "go_molecular_function": "GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0070527 platelet aggregation;GO:0009968 negative regulation of signal transduction;GO:0051279 regulation of release of sequestered calcium ion into cytosol;GO:0045779 negative regulation of bone resorption;GO:0045670 regulation of osteoclast differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FWX7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FSM1-1", "uniprot_id": [ { "id": "A0A9J7FSM1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FSM1", "type": "external" } ], "mass": 43773.0, "length": 393, "protein_name": "Ras-related protein Rab-3", "gene_name": "LOC100755455", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: ras-related protein Rab-3D", "refseq_ac": [ { "id": "XP_027267388", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267388", "type": "external" } ], "gene_names_uniprotkb": "LOC100755455", "gene_names_refseq": "LOC100755455", "protein_names_uniprotkb": "Ras-related protein Rab-3", "protein_names_refseq": "LOW QUALITY PROTEIN: ras-related protein Rab-3D", "tax_id": 10029, "disease": "", "pathway": " (cge:100755455)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB3D may be involved in the insulin-induced exocytosis of GLUT4-containing vesicles in adipocytes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" } ], "go_molecular_function": "GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030141 secretory granule", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006887 exocytosis;GO:0017157 regulation of exocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FSM1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FT87-1", "uniprot_id": [ { "id": "A0A9J7FT87_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FT87", "type": "external" } ], "mass": 133888.0, "length": 1186, "protein_name": "Tyrosine-protein kinase", "gene_name": "Tyk2", "organism": "Hamster", "refseq_name": "non-receptor tyrosine-protein kinase TYK2 isoform X1", "refseq_ac": [ { "id": "XP_007638684", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638684", "type": "external" } ], "gene_names_uniprotkb": "Tyk2", "gene_names_refseq": "Tyk2", "protein_names_uniprotkb": "Tyrosine-protein kinase; 2.7.10.2", "protein_names_refseq": "non-receptor tyrosine-protein kinase TYK2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100760469)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613752.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0005131 growth hormone receptor binding", "go_cellular_component": "GO:0005829 cytosol;GO:0016020 membrane;GO:0005856 cytoskeleton", "go_biological_process": "GO:0030154 cell differentiation;GO:0035556 intracellular signal transduction;GO:0045087 innate immune response;GO:0022407 regulation of cell-cell adhesion;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FT87-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FSU0-1", "uniprot_id": [ { "id": "A0A9J7FSU0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FSU0", "type": "external" } ], "mass": 107354.0, "length": 954, "protein_name": "Xylosyltransferase 1", "gene_name": "Xylt1", "organism": "Hamster", "refseq_name": "xylosyltransferase 1 isoform X2", "refseq_ac": [ { "id": "XP_027265954", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265954", "type": "external" } ], "gene_names_uniprotkb": "Xylt1", "gene_names_refseq": "Xylt1", "protein_names_uniprotkb": "Xylosyltransferase 1; 2.4.2.26; Peptide O-xylosyltransferase 1; Xylosyltransferase I", "protein_names_refseq": "xylosyltransferase 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756878)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.26", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0030158 protein xylosyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0015012 heparan sulfate proteoglycan biosynthetic process;GO:0050650 chondroitin sulfate proteoglycan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FSU0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FT36-1", "uniprot_id": [ { "id": "A0A9J7FT36_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FT36", "type": "external" } ], "mass": 139395.0, "length": 1300, "protein_name": "Latent-transforming growth factor beta-binding protein 3", "gene_name": "Ltbp3", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: latent-transforming growth factor beta-binding protein 3 isoform X6", "refseq_ac": [ { "id": "XP_027264352", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264352", "type": "external" } ], "gene_names_uniprotkb": "Ltbp3", "gene_names_refseq": "Ltbp3", "protein_names_uniprotkb": "Latent-transforming growth factor beta-binding protein 3", "protein_names_refseq": "LOW QUALITY PROTEIN: latent-transforming growth factor beta-binding protein 3 isoform X6", "tax_id": 10029, "disease": "", "pathway": " (cge:100772206)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019838 growth factor binding;GO:0005509 calcium ion binding", "go_cellular_component": "", "go_biological_process": "GO:0048286 lung alveolus development;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0045595 regulation of cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FT36-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FT68-1", "uniprot_id": [ { "id": "A0A9J7FT68_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FT68", "type": "external" } ], "mass": 99358.0, "length": 906, "protein_name": "A disintegrin and metalloproteinase with thrombospondin motifs 8", "gene_name": "Adamts8", "organism": "Hamster", "refseq_name": "A disintegrin and metalloproteinase with thrombospondin motifs 8", "refseq_ac": [ { "id": "XP_027267536", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267536", "type": "external" } ], "gene_names_uniprotkb": "Adamts8", "gene_names_refseq": "Adamts8", "protein_names_uniprotkb": "A disintegrin and metalloproteinase with thrombospondin motifs 8", "protein_names_refseq": "A disintegrin and metalloproteinase with thrombospondin motifs 8", "tax_id": 10029, "disease": "", "pathway": " (cge:100754641)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008201 heparin binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0031012 extracellular matrix", "go_biological_process": "GO:0006508 proteolysis;GO:0030198 extracellular matrix organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FT68-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FUZ5-1", "uniprot_id": [ { "id": "A0A9J7FUZ5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FUZ5", "type": "external" } ], "mass": 182830.0, "length": 1613, "protein_name": "DNA (cytosine-5)-methyltransferase", "gene_name": "Dnmt1", "organism": "Hamster", "refseq_name": "DNA (cytosine-5)-methyltransferase 1 isoform X4", "refseq_ac": [ { "id": "XP_027267272", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267272", "type": "external" } ], "gene_names_uniprotkb": "Dnmt1", "gene_names_refseq": "Dnmt1", "protein_names_uniprotkb": "DNA (cytosine-5)-methyltransferase; 2.1.1.37", "protein_names_refseq": "DNA (cytosine-5)-methyltransferase 1 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100762713)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.37", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.37", "type": "external" } ], "go_molecular_function": "GO:0003886 DNA (cytosine-5-)-methyltransferase activity;GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0032259 methylation;GO:0044027 negative regulation of gene expression via chromosomal CpG island methylation;GO:1903925 response to bisphenol A", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FUZ5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FTB0-1", "uniprot_id": [ { "id": "A0A9J7FTB0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FTB0", "type": "external" } ], "mass": 53882.0, "length": 474, "protein_name": "Synaptotagmin-17", "gene_name": "Syt17", "organism": "Hamster", "refseq_name": "synaptotagmin-17 isoform X2", "refseq_ac": [ { "id": "XP_027265958", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265958", "type": "external" } ], "gene_names_uniprotkb": "Syt17", "gene_names_refseq": "Syt17", "protein_names_uniprotkb": "Synaptotagmin-17; Protein B/K; Synaptotagmin XVII", "protein_names_refseq": "synaptotagmin-17 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100770209)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays a role in dendrite formation by melanocytes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0005544 calcium-dependent phospholipid binding;GO:0030276 clathrin binding;GO:0000149 SNARE binding;GO:0001786 phosphatidylserine binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0070382 exocytic vesicle", "go_biological_process": "GO:0030154 cell differentiation;GO:0017156 calcium-ion regulated exocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FTB0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FTE1-1", "uniprot_id": [ { "id": "A0A9J7FTE1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FTE1", "type": "external" } ], "mass": 34972.0, "length": 318, "protein_name": "Lymphatic vessel endothelial hyaluronic acid receptor 1", "gene_name": "Lyve1", "organism": "Hamster", "refseq_name": "lymphatic vessel endothelial hyaluronic acid receptor 1", "refseq_ac": [ { "id": "XP_007647074", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007647074", "type": "external" } ], "gene_names_uniprotkb": "Lyve1", "gene_names_refseq": "Lyve1", "protein_names_uniprotkb": "Lymphatic vessel endothelial hyaluronic acid receptor 1; Cell surface retention sequence-binding protein 1; Extracellular link domain-containing protein 1", "protein_names_refseq": "lymphatic vessel endothelial hyaluronic acid receptor 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100759540)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614511.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes. Binds to pericelluar hyaluronan matrices deposited on the surface of leukocytes and facilitates cell adhesion and migration through lymphatic endothelium., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0005540 hyaluronic acid binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007155 cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FTE1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FTE2-1", "uniprot_id": [ { "id": "A0A9J7FTE2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FTE2", "type": "external" } ], "mass": 82070.0, "length": 724, "protein_name": "Eukaryotic elongation factor 2 kinase", "gene_name": "Eef2k", "organism": "Hamster", "refseq_name": "eukaryotic elongation factor 2 kinase isoform X1", "refseq_ac": [ { "id": "XP_027266031", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266031", "type": "external" } ], "gene_names_uniprotkb": "Eef2k", "gene_names_refseq": "Eef2k", "protein_names_uniprotkb": "Eukaryotic elongation factor 2 kinase; 2.7.11.20", "protein_names_refseq": "eukaryotic elongation factor 2 kinase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100765385)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.20", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.20", "type": "external" } ], "go_molecular_function": "GO:0004686 elongation factor-2 kinase activity;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0005509 calcium ion binding;GO:0003746 translation elongation factor activity", "go_cellular_component": "", "go_biological_process": "GO:0031037 myosin II filament disassembly;GO:1903013 response to differentiation-inducing factor 1", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FTE2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FTF7-1", "uniprot_id": [ { "id": "A0A9J7FTF7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FTF7", "type": "external" } ], "mass": 121216.0, "length": 1092, "protein_name": "Phosphodiesterase", "gene_name": "Pde3b", "organism": "Hamster", "refseq_name": "cGMP-inhibited 3',5'-cyclic phosphodiesterase B isoform X2", "refseq_ac": [ { "id": "XP_027265935", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265935", "type": "external" } ], "gene_names_uniprotkb": "Pde3b", "gene_names_refseq": "Pde3b", "protein_names_uniprotkb": "Phosphodiesterase; 3.1.4.-", "protein_names_refseq": "cGMP-inhibited 3',5'-cyclic phosphodiesterase B isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100775064)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.4.35", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.35", "type": "external" }, { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" }, { "id": "3.1.4.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.53", "type": "external" }, { "id": "3.1.4.17", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.17", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FTF7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FTH9-1", "uniprot_id": [ { "id": "A0A9J7FTH9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FTH9", "type": "external" } ], "mass": 430481.0, "length": 3963, "protein_name": "Histone-lysine N-methyltransferase", "gene_name": "Kmt2a", "organism": "Hamster", "refseq_name": "histone-lysine N-methyltransferase 2A isoform X2", "refseq_ac": [ { "id": "XP_027267779", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267779", "type": "external" } ], "gene_names_uniprotkb": "Kmt2a", "gene_names_refseq": "Kmt2a", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase; 2.1.1.364", "protein_names_refseq": "histone-lysine N-methyltransferase 2A isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100760424)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 6, "predicted_n_glycosites": 0, "predicted_o_glycosites": 6, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" }, { "id": "2.1.1.37", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.37", "type": "external" }, { "id": "2.1.1.364", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.364", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0140945 histone H3K4 monomethyltransferase activity", "go_cellular_component": "GO:0035097 histone methyltransferase complex", "go_biological_process": "GO:0035162 embryonic hemopoiesis;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0048511 rhythmic process;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FTH9-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FTJ1-1", "uniprot_id": [ { "id": "A0A9J7FTJ1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FTJ1", "type": "external" } ], "mass": 93606.0, "length": 841, "protein_name": "Phosphatidylinositol-glycan-specific phospholipase D", "gene_name": "Gpld1", "organism": "Hamster", "refseq_name": "phosphatidylinositol-glycan-specific phospholipase D", "refseq_ac": [ { "id": "XP_007641003", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641003", "type": "external" } ], "gene_names_uniprotkb": "Gpld1", "gene_names_refseq": "Gpld1", "protein_names_uniprotkb": "Phosphatidylinositol-glycan-specific phospholipase D; 3.1.4.50; Glycoprotein phospholipase D; Glycosyl-phosphatidylinositol-specific phospholipase D", "protein_names_refseq": "phosphatidylinositol-glycan-specific phospholipase D", "tax_id": 10029, "disease": "", "pathway": " (cge:100759513)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613881.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Hydrolyzes the inositol phosphate linkage of glycosylphosphatidylinositol (GPI)-anchored membrane proteins, thereby releasing them from the cell surface. Cleaves on the inositol side of the anchor, leaving the phosphate group attached to the membrane. This release of GPI-anchored proteins can modulate diverse biological processes, including the activation of signaling pathways., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.4.50", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.50", "type": "external" } ], "go_molecular_function": "GO:0004621 glycosylphosphatidylinositol phospholipase D activity", "go_cellular_component": "GO:0031012 extracellular matrix;GO:0034364 high-density lipoprotein particle", "go_biological_process": "GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FTJ1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FTL0-1", "uniprot_id": [ { "id": "A0A9J7FTL0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FTL0", "type": "external" } ], "mass": 164023.0, "length": 1505, "protein_name": "LOW QUALITY PROTEIN: cyclin-dependent kinase 13 isoform X2", "gene_name": "Cdk13", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: cyclin-dependent kinase 13 isoform X2", "refseq_ac": [ { "id": "XP_027265189", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265189", "type": "external" } ], "gene_names_uniprotkb": "Cdk13", "gene_names_refseq": "Cdk13", "protein_names_uniprotkb": "LOW QUALITY PROTEIN: cyclin-dependent kinase 13 isoform X2", "protein_names_refseq": "LOW QUALITY PROTEIN: cyclin-dependent kinase 13 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772207)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004693 cyclin-dependent protein serine/threonine kinase activity;GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity;GO:0030332 cyclin binding", "go_cellular_component": "GO:0016607 nuclear speck;GO:0008024 cyclin/CDK positive transcription elongation factor complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0008380 RNA splicing;GO:0032968 positive regulation of transcription elongation by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FTL0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FTT6-1", "uniprot_id": [ { "id": "A0A9J7FTT6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FTT6", "type": "external" } ], "mass": 200120.0, "length": 1787, "protein_name": "Poly [ADP-ribose] polymerase", "gene_name": "Parp14", "organism": "Hamster", "refseq_name": "protein mono-ADP-ribosyltransferase PARP14", "refseq_ac": [ { "id": "XP_027268564", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268564", "type": "external" } ], "gene_names_uniprotkb": "Parp14", "gene_names_refseq": "Parp14", "protein_names_uniprotkb": "Poly [ADP-ribose] polymerase; 2.4.2.-; PARP", "protein_names_refseq": "protein mono-ADP-ribosyltransferase PARP14", "tax_id": 10029, "disease": "", "pathway": " (cge:100758989)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity;GO:0003714 transcription corepressor activity;GO:0016779 nucleotidyltransferase activity;GO:0003950 NAD+ poly-ADP-ribosyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0001961 positive regulation of cytokine-mediated signaling pathway;GO:0010629 negative regulation of gene expression;GO:0045087 innate immune response;GO:0060334 regulation of type II interferon-mediated signaling pathway;GO:0070212 protein poly-ADP-ribosylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FTT6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FTX9-1", "uniprot_id": [ { "id": "A0A9J7FTX9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FTX9", "type": "external" } ], "mass": 81839.0, "length": 723, "protein_name": "Glutamate--cysteine ligase", "gene_name": "Gclc", "organism": "Hamster", "refseq_name": "glutamate--cysteine ligase catalytic subunit isoform X3", "refseq_ac": [ { "id": "XP_027266910", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266910", "type": "external" } ], "gene_names_uniprotkb": "Gclc", "gene_names_refseq": "Gclc", "protein_names_uniprotkb": "Glutamate--cysteine ligase; 6.3.2.2; Gamma-ECS; Gamma-glutamylcysteine synthetase", "protein_names_refseq": "glutamate--cysteine ligase catalytic subunit isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100752019)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the ATP-dependent ligation of L-glutamate and L-cysteine and participates in the first and rate-limiting step in glutathione biosynthesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.3.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.2.2", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004357 glutamate-cysteine ligase activity", "go_cellular_component": "GO:0017109 glutamate-cysteine ligase complex", "go_biological_process": "GO:0006750 glutathione biosynthetic process;GO:0043066 negative regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FTX9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FTZ6-1", "uniprot_id": [ { "id": "A0A9J7FTZ6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FTZ6", "type": "external" } ], "mass": 49912.0, "length": 458, "protein_name": "Cell adhesion molecule 1", "gene_name": "Cadm1", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: cell adhesion molecule 1 isoform X2", "refseq_ac": [ { "id": "XP_027267861", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267861", "type": "external" } ], "gene_names_uniprotkb": "Cadm1", "gene_names_refseq": "Cadm1", "protein_names_uniprotkb": "Cell adhesion molecule 1; Synaptic cell adhesion molecule", "protein_names_refseq": "LOW QUALITY PROTEIN: cell adhesion molecule 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100766050)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045202 synapse;GO:0043005 neuron projection", "go_biological_process": "GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0008037 cell recognition;GO:0042271 susceptibility to natural killer cell mediated cytotoxicity;GO:0051606 detection of stimulus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FTZ6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FTZ7-1", "uniprot_id": [ { "id": "A0A9J7FTZ7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FTZ7", "type": "external" } ], "mass": 48431.0, "length": 439, "protein_name": "Ornithine aminotransferase", "gene_name": "Oat", "organism": "Hamster", "refseq_name": "ornithine aminotransferase, mitochondrial", "refseq_ac": [ { "id": "XP_027264945", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264945", "type": "external" } ], "gene_names_uniprotkb": "Oat", "gene_names_refseq": "Oat", "protein_names_uniprotkb": "Ornithine aminotransferase; 2.6.1.13", "protein_names_refseq": "ornithine aminotransferase, mitochondrial", "tax_id": 10029, "disease": "", "pathway": " (cge:100771896)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the reversible interconversion of L-ornithine and 2-oxoglutarate to L-glutamate semialdehyde and L-glutamate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.6.1.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.13", "type": "external" } ], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0042802 identical protein binding;GO:0004587 ornithine aminotransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0010121 L-arginine catabolic process to proline via ornithine;GO:0019544 L-arginine catabolic process to L-glutamate", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FTZ7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FU13-1", "uniprot_id": [ { "id": "A0A9J7FU13_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FU13", "type": "external" } ], "mass": 105567.0, "length": 967, "protein_name": "A disintegrin and metalloproteinase with thrombospondin motifs 1", "gene_name": "Adamts1", "organism": "Hamster", "refseq_name": "A disintegrin and metalloproteinase with thrombospondin motifs 1 isoform X2", "refseq_ac": [ { "id": "XP_027268160", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268160", "type": "external" } ], "gene_names_uniprotkb": "Adamts1", "gene_names_refseq": "Adamts1", "protein_names_uniprotkb": "A disintegrin and metalloproteinase with thrombospondin motifs 1", "protein_names_refseq": "A disintegrin and metalloproteinase with thrombospondin motifs 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100761390)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008201 heparin binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0031012 extracellular matrix", "go_biological_process": "GO:0006508 proteolysis;GO:0030198 extracellular matrix organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FU13-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FU67-1", "uniprot_id": [ { "id": "A0A9J7FU67_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FU67", "type": "external" } ], "mass": 107224.0, "length": 956, "protein_name": "Glutamate receptor", "gene_name": "Grik4", "organism": "Hamster", "refseq_name": "glutamate receptor ionotropic, kainate 4 isoform X2", "refseq_ac": [ { "id": "XP_027268000", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268000", "type": "external" } ], "gene_names_uniprotkb": "Grik4", "gene_names_refseq": "Grik4", "protein_names_uniprotkb": "Glutamate receptor", "protein_names_refseq": "glutamate receptor ionotropic, kainate 4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767895)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027268000.1. COMPLETENESS: full length., [RefSeq]; Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0045211 postsynaptic membrane;GO:0042734 presynaptic membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FU67-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FVW3-1", "uniprot_id": [ { "id": "A0A9J7FVW3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FVW3", "type": "external" } ], "mass": 91478.0, "length": 827, "protein_name": "Integrin beta", "gene_name": "Itgb5", "organism": "Hamster", "refseq_name": "integrin beta-5 isoform X4", "refseq_ac": [ { "id": "XP_027268596", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268596", "type": "external" } ], "gene_names_uniprotkb": "Itgb5", "gene_names_refseq": "Itgb5", "protein_names_uniprotkb": "Integrin beta", "protein_names_refseq": "integrin beta-5 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100765378)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Integrin alpha-V/beta-5 (ITGAV:ITGB5) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005925 focal adhesion;GO:0009986 cell surface;GO:0034684 integrin alphav-beta5 complex;GO:0008305 integrin complex", "go_biological_process": "GO:0007229 integrin-mediated signaling pathway;GO:0016477 cell migration;GO:0007160 cell-matrix adhesion;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0033627 cell adhesion mediated by integrin", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FVW3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FUD8-1", "uniprot_id": [ { "id": "A0A9J7FUD8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FUD8", "type": "external" } ], "mass": 59130.0, "length": 520, "protein_name": "Cytochrome b5 reductase 4", "gene_name": "LOC100760537", "organism": "Hamster", "refseq_name": "cytochrome b5 reductase 4 isoform X1", "refseq_ac": [ { "id": "XP_027266799", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266799", "type": "external" } ], "gene_names_uniprotkb": "LOC100760537", "gene_names_refseq": "LOC100760537", "protein_names_uniprotkb": "Cytochrome b5 reductase 4; 1.6.2.2; Flavohemoprotein b5/b5R; N-terminal cytochrome b5 and cytochrome b5 oxidoreductase domain-containing protein; cb5/cb5R", "protein_names_refseq": "cytochrome b5 reductase 4 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100760537)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.2.2", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0090524 cytochrome-b5 reductase activity, acting on NADH", "go_cellular_component": "GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0006801 superoxide metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FUD8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FUG1-1", "uniprot_id": [ { "id": "A0A9J7FUG1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FUG1", "type": "external" } ], "mass": 90855.0, "length": 804, "protein_name": "Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein", "gene_name": "Acap2", "organism": "Hamster", "refseq_name": "arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 isoform X1", "refseq_ac": [ { "id": "XP_007638647", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638647", "type": "external" } ], "gene_names_uniprotkb": "Acap2", "gene_names_refseq": "Acap2", "protein_names_uniprotkb": "Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein; Centaurin-beta; Cnt-b", "protein_names_refseq": "arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100760438)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613591.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6). Doesn't show GAP activity for RAB35., [UniProtKB, UniProtKB, UniProtKB]; GTPase-activating protein for the ADP ribosylation factor family., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0010008 endosome membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FUG1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FUG5-1", "uniprot_id": [ { "id": "A0A9J7FUG5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FUG5", "type": "external" } ], "mass": 50487.0, "length": 456, "protein_name": "Phospholipase A1 member A", "gene_name": "Pla1a", "organism": "Hamster", "refseq_name": "phospholipase A1 member A isoform X1", "refseq_ac": [ { "id": "XP_027268493", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268493", "type": "external" } ], "gene_names_uniprotkb": "Pla1a", "gene_names_refseq": "Pla1a", "protein_names_uniprotkb": "Phospholipase A1 member A; 3.1.1.111; Phosphatidylserine-specific phospholipase A1", "protein_names_refseq": "phospholipase A1 member A isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100759743)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Hydrolyzes the ester bond of the acyl group attached at the sn-1 position of phosphatidylserines (phospholipase A1 activity) and 1-acyl-2-lysophosphatidylserines (lysophospholipase activity) in the pathway of phosphatidylserines acyl chain remodeling. Cleaves phosphatidylserines exposed on the outer leaflet of the plasma membrane of apoptotic cells producing 2-acyl-1-lysophosphatidylserines, which in turn enhance mast cell activation and histamine production. Has no activity toward other glycerophospholipids including phosphatidylcholines, phosphatidylethanolamines, phosphatidic acids or phosphatidylinositols, or glycerolipids such as triolein., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.111", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.111", "type": "external" }, { "id": "3.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0008970 phospholipase A1 activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0016042 lipid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FUG5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FUL0-1", "uniprot_id": [ { "id": "A0A9J7FUL0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FUL0", "type": "external" } ], "mass": 410012.0, "length": 3659, "protein_name": "Serine/threonine-protein kinase SMG1", "gene_name": "Smg1", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: serine/threonine-protein kinase SMG1 isoform X3", "refseq_ac": [ { "id": "XP_027265956", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265956", "type": "external" } ], "gene_names_uniprotkb": "Smg1", "gene_names_refseq": "Smg1", "protein_names_uniprotkb": "Serine/threonine-protein kinase SMG1; 2.7.11.1; Lambda/iota protein kinase C-interacting protein; Nonsense mediated mRNA decay-associated PI3K-related kinase SMG1", "protein_names_refseq": "LOW QUALITY PROTEIN: serine/threonine-protein kinase SMG1 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100752584)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027265956.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FUL0-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FUS7-1", "uniprot_id": [ { "id": "A0A9J7FUS7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FUS7", "type": "external" } ], "mass": 68493.0, "length": 599, "protein_name": "Proline dehydrogenase", "gene_name": "Prodh", "organism": "Hamster", "refseq_name": "proline dehydrogenase 1, mitochondrial isoform X2", "refseq_ac": [ { "id": "XP_027268949", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268949", "type": "external" } ], "gene_names_uniprotkb": "Prodh", "gene_names_refseq": "Prodh", "protein_names_uniprotkb": "Proline dehydrogenase; 1.5.5.2", "protein_names_refseq": "proline dehydrogenase 1, mitochondrial isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100750856)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Converts proline to delta-1-pyrroline-5-carboxylate., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.5.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.5.2", "type": "external" } ], "go_molecular_function": "GO:0071949 FAD binding;GO:0004657 proline dehydrogenase activity", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0010133 L-proline catabolic process to L-glutamate", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FUS7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FUX7-1", "uniprot_id": [ { "id": "A0A9J7FUX7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FUX7", "type": "external" } ], "mass": 109968.0, "length": 994, "protein_name": "Ephrin type-B receptor 3", "gene_name": "Ephb3", "organism": "Hamster", "refseq_name": "ephrin type-B receptor 3 isoform X1", "refseq_ac": [ { "id": "XP_007650187", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650187", "type": "external" } ], "gene_names_uniprotkb": "Ephb3", "gene_names_refseq": "Ephb3", "protein_names_uniprotkb": "Ephrin type-B receptor 3; 2.7.10.1", "protein_names_refseq": "ephrin type-B receptor 3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100774807)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615122.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0005005 transmembrane-ephrin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030425 dendrite", "go_biological_process": "GO:0016477 cell migration;GO:0007417 central nervous system development;GO:0060996 dendritic spine development;GO:0007411 axon guidance;GO:0048513 animal organ development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FUX7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FV90-1", "uniprot_id": [ { "id": "A0A9J7FV90_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FV90", "type": "external" } ], "mass": 19404.0, "length": 180, "protein_name": "Adenine phosphoribosyltransferase", "gene_name": "Aprt", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Aprt", "gene_names_refseq": "", "protein_names_uniprotkb": "Adenine phosphoribosyltransferase; 2.4.2.7", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100765665)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.2.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.7", "type": "external" } ], "go_molecular_function": "GO:0016208 AMP binding;GO:0002055 adenine binding;GO:0003999 adenine phosphoribosyltransferase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0044209 AMP salvage;GO:0032264 IMP salvage;GO:0006166 purine ribonucleoside salvage;GO:0006168 adenine salvage", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FV90-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FV95-1", "uniprot_id": [ { "id": "A0A9J7FV95_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FV95", "type": "external" } ], "mass": 140943.0, "length": 1258, "protein_name": "Cation-transporting ATPase", "gene_name": "LOC100751095", "organism": "Hamster", "refseq_name": "probable cation-transporting ATPase 13A5 isoform X3", "refseq_ac": [ { "id": "XP_027269074", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269074", "type": "external" } ], "gene_names_uniprotkb": "LOC100751095", "gene_names_refseq": "LOC100751095", "protein_names_uniprotkb": "Cation-transporting ATPase; 7.2.2.-", "protein_names_refseq": "probable cation-transporting ATPase 13A5 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100751095)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 4% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027269074.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity;GO:0015662 P-type ion transporter activity", "go_cellular_component": "GO:0031902 late endosome membrane", "go_biological_process": "GO:0006874 intracellular calcium ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FV95-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FXI6-1", "uniprot_id": [ { "id": "A0A9J7FXI6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FXI6", "type": "external" } ], "mass": 118330.0, "length": 1069, "protein_name": "Enteropeptidase", "gene_name": "Tmprss15", "organism": "Hamster", "refseq_name": "enteropeptidase isoform X2", "refseq_ac": [ { "id": "XP_027269119", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269119", "type": "external" } ], "gene_names_uniprotkb": "Tmprss15", "gene_names_refseq": "Tmprss15", "protein_names_uniprotkb": "Enteropeptidase; 3.4.21.9; Enterokinase; Serine protease 7; Transmembrane protease serine 15", "protein_names_refseq": "enteropeptidase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754500)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FXI6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FVQ6-1", "uniprot_id": [ { "id": "A0A9J7FVQ6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FVQ6", "type": "external" } ], "mass": 41364.0, "length": 376, "protein_name": "Ras-related protein Rab-35", "gene_name": "Rab35", "organism": "Hamster", "refseq_name": "ras-related protein Rab-35 isoform X2", "refseq_ac": [ { "id": "XP_027269590", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269590", "type": "external" } ], "gene_names_uniprotkb": "Rab35", "gene_names_refseq": "Rab35", "protein_names_uniprotkb": "Ras-related protein Rab-35; 3.6.5.2", "protein_names_refseq": "ras-related protein Rab-35 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100760151)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 32% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" } ], "go_molecular_function": "GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0005768 endosome;GO:0005886 plasma membrane;GO:0005905 clathrin-coated pit;GO:0042470 melanosome;GO:0030136 clathrin-coated vesicle", "go_biological_process": "GO:0015031 protein transport;GO:0032482 Rab protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FVQ6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FVR6-1", "uniprot_id": [ { "id": "A0A9J7FVR6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FVR6", "type": "external" } ], "mass": 243908.0, "length": 2141, "protein_name": "Citron Rho-interacting kinase", "gene_name": "Cit", "organism": "Hamster", "refseq_name": "citron Rho-interacting kinase isoform X1", "refseq_ac": [ { "id": "XP_016832373", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016832373", "type": "external" } ], "gene_names_uniprotkb": "Cit", "gene_names_refseq": "Cit", "protein_names_uniprotkb": "Citron Rho-interacting kinase; 2.7.11.1; Rho-interacting, serine/threonine-protein kinase 21", "protein_names_refseq": "citron Rho-interacting kinase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100755517)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613605.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_016832373.1. COMPLETENESS: full length., [RefSeq]; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0032535 regulation of cellular component size;GO:0044772 mitotic cell cycle phase transition;GO:0000281 mitotic cytokinesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FVR6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FW31-1", "uniprot_id": [ { "id": "A0A9J7FW31_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FW31", "type": "external" } ], "mass": 37540.0, "length": 337, "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "Rad9b", "organism": "Hamster", "refseq_name": "cell cycle checkpoint control protein RAD9B", "refseq_ac": [ { "id": "XP_027269648", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269648", "type": "external" } ], "gene_names_uniprotkb": "Rad9b", "gene_names_refseq": "Rad9b", "protein_names_uniprotkb": "Cell cycle checkpoint control protein RAD9A; 3.1.11.2; DNA repair exonuclease rad9 homolog A", "protein_names_refseq": "cell cycle checkpoint control protein RAD9B", "tax_id": 10029, "disease": "", "pathway": " (cge:100764146)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613692.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds; endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths; and DNA ligase I (LIG1) on long-patch base excision repair substrates. The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase. RAD9A possesses 3'->5' double stranded DNA exonuclease activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008311 double-stranded DNA 3'-5' DNA exonuclease activity", "go_cellular_component": "GO:0030896 checkpoint clamp complex", "go_biological_process": "GO:0000076 DNA replication checkpoint signaling;GO:0006281 DNA repair;GO:0071479 cellular response to ionizing radiation;GO:0031573 mitotic intra-S DNA damage checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FW31-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FW36-1", "uniprot_id": [ { "id": "A0A9J7FW36_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FW36", "type": "external" } ], "mass": 79647.0, "length": 701, "protein_name": "Mannan-binding lectin serine protease 1", "gene_name": "Masp1", "organism": "Hamster", "refseq_name": "mannan-binding lectin serine protease 1", "refseq_ac": [ { "id": "XP_003495652", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495652", "type": "external" } ], "gene_names_uniprotkb": "Masp1", "gene_names_refseq": "Masp1", "protein_names_uniprotkb": "Mannan-binding lectin serine protease 1; Complement-activating component of Ra-reactive factor; Mannose-binding lectin-associated serine protease 1; Mannose-binding protein-associated serine protease; Ra-reactive factor serine protease p100; Serine protease 5", "protein_names_refseq": "mannan-binding lectin serine protease 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100774526)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Precursor of a serum protease that activates the complement pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system., [UniProtKB, UniProtKB]; Serine protease that activates the alternative pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. The alternative complement pathway acts as an amplification loop that enhances other complement pathways. Isoform MASP-3 specifically catalyzes cleavage and activation of factor D (CFD), the protease that initiates the alternative complement pathway., [UniProtKB, UniProtKB]; Serine protease that activates the lectin pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. The lectin complement system is activated following association of lectins, such as MBL2, FCN1, FCN2 or FCN3, to carbohydrates on the pathogen surface. Following autoproteolytic processing in response to lectin-binding to pathogen carbohydrates, catalyzes cleavage and activation of MASP2, the next component of the lectin complement pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006508 proteolysis;GO:0001867 complement activation, lectin pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FW36-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FW45-1", "uniprot_id": [ { "id": "A0A9J7FW45_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FW45", "type": "external" } ], "mass": 46593.0, "length": 418, "protein_name": "Hyaluronidase", "gene_name": "Hyal3", "organism": "Hamster", "refseq_name": "hyaluronidase-3", "refseq_ac": [ { "id": "XP_027270275", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270275", "type": "external" } ], "gene_names_uniprotkb": "Hyal3", "gene_names_refseq": "Hyal3", "protein_names_uniprotkb": "Hyaluronidase; 3.2.1.35", "protein_names_refseq": "hyaluronidase-3", "tax_id": 10029, "disease": "", "pathway": " (cge:100753318)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004415 hyalurononglucosaminidase activity", "go_cellular_component": "GO:0001669 acrosomal vesicle", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0030214 hyaluronan catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FW45-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FW54-1", "uniprot_id": [ { "id": "A0A9J7FW54_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FW54", "type": "external" } ], "mass": 51876.0, "length": 476, "protein_name": "Isobutyryl-CoA dehydrogenase, mitochondrial", "gene_name": "Acad8", "organism": "Hamster", "refseq_name": "isobutyryl-CoA dehydrogenase, mitochondrial", "refseq_ac": [ { "id": "XP_027267980", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267980", "type": "external" } ], "gene_names_uniprotkb": "Acad8", "gene_names_refseq": "Acad8", "protein_names_uniprotkb": "Isobutyryl-CoA dehydrogenase, mitochondrial; 1.3.8.5; Acyl-CoA dehydrogenase family member 8", "protein_names_refseq": "isobutyryl-CoA dehydrogenase, mitochondrial", "tax_id": 10029, "disease": "", "pathway": " (cge:100751213)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 8% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027267980.1. COMPLETENESS: full length., [RefSeq]; Isobutyryl-CoA dehydrogenase which catalyzes the conversion of 2-methylpropanoyl-CoA to (2E)-2-methylpropenoyl-CoA in the valine catabolic pathway. To a lesser extent, also able to catalyze the oxidation of (2S)-2-methylbutanoyl-CoA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.3.8.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.1", "type": "external" }, { "id": "1.3.8.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.5", "type": "external" } ], "go_molecular_function": "GO:0050660 flavin adenine dinucleotide binding;GO:0003853 short-chain 2-methyl fatty acyl-CoA dehydrogenase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0009083 branched-chain amino acid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FW54-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FW85-1", "uniprot_id": [ { "id": "A0A9J7FW85_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FW85", "type": "external" } ], "mass": 44633.0, "length": 411, "protein_name": "Lysosome-associated membrane glycoprotein 3", "gene_name": "Lamp3", "organism": "Hamster", "refseq_name": "lysosome-associated membrane glycoprotein 3", "refseq_ac": [ { "id": "XP_027268893", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268893", "type": "external" } ], "gene_names_uniprotkb": "Lamp3", "gene_names_refseq": "Lamp3", "protein_names_uniprotkb": "Lysosome-associated membrane glycoprotein 3", "protein_names_refseq": "lysosome-associated membrane glycoprotein 3", "tax_id": 10029, "disease": "", "pathway": " (cge:100757631)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Lysosomal membrane glycoprotein which plays a role in the unfolded protein response (UPR) that contributes to protein degradation and cell survival during proteasomal dysfunction. Plays a role in the process of fusion of the lysosome with the autophagosome, thereby modulating the autophagic process. Promotes hepatocellular lipogenesis through activation of the PI3K/Akt pathway. May also play a role in dendritic cell function and in adaptive immunity., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0031901 early endosome membrane", "go_biological_process": "GO:0072594 establishment of protein localization to organelle;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FW85-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FWY1-1", "uniprot_id": [ { "id": "A0A9J7FWY1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FWY1", "type": "external" } ], "mass": 92089.0, "length": 814, "protein_name": "Kinesin-like protein", "gene_name": "Kif9", "organism": "Hamster", "refseq_name": "kinesin-like protein KIF9 isoform X2", "refseq_ac": [ { "id": "XP_027270472", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270472", "type": "external" } ], "gene_names_uniprotkb": "Kif9", "gene_names_refseq": "Kif9", "protein_names_uniprotkb": "Kinesin-like protein", "protein_names_refseq": "kinesin-like protein KIF9 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100768828)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Essential for normal male fertility and for progressive motility of spermatozoa., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0003777 microtubule motor activity", "go_cellular_component": "GO:0005874 microtubule", "go_biological_process": "GO:0007018 microtubule-based movement", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FWY1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FWE5-1", "uniprot_id": [ { "id": "A0A9J7FWE5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FWE5", "type": "external" } ], "mass": 199209.0, "length": 1767, "protein_name": "E3 ubiquitin-protein ligase listerin", "gene_name": "Ltn1", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase listerin isoform X1", "refseq_ac": [ { "id": "XP_007639944", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639944", "type": "external" } ], "gene_names_uniprotkb": "Ltn1", "gene_names_refseq": "Ltn1", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase listerin; 2.3.2.27; RING-type E3 ubiquitin transferase listerin", "protein_names_refseq": "E3 ubiquitin-protein ligase listerin isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100760736)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 106 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613595.1) and transcript sequence (JI882180.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0043023 ribosomal large subunit binding", "go_cellular_component": "GO:0005829 cytosol;GO:1990112 RQC complex", "go_biological_process": "GO:0072344 rescue of stalled ribosome;GO:1990116 ribosome-associated ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FWE5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FWJ6-1", "uniprot_id": [ { "id": "A0A9J7FWJ6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FWJ6", "type": "external" } ], "mass": 45076.0, "length": 421, "protein_name": "Dual specificity protein phosphatase", "gene_name": "Dusp7", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: dual specificity protein phosphatase 7 isoform X2", "refseq_ac": [ { "id": "XP_027270194", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270194", "type": "external" } ], "gene_names_uniprotkb": "Dusp7", "gene_names_refseq": "Dusp7", "protein_names_uniprotkb": "Dual specificity protein phosphatase; 3.1.3.16; 3.1.3.48", "protein_names_refseq": "LOW QUALITY PROTEIN: dual specificity protein phosphatase 7 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100765417)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.52", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.52", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21", "type": "external" }, { "id": "3.1.3.74", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.74", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" } ], "go_molecular_function": "GO:0004722 protein serine/threonine phosphatase activity;GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0008330 protein tyrosine/threonine phosphatase activity;GO:0033550 MAP kinase tyrosine phosphatase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0043409 negative regulation of MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FWJ6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FWS5-1", "uniprot_id": [ { "id": "A0A9J7FWS5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FWS5", "type": "external" } ], "mass": 43829.0, "length": 394, "protein_name": "Endonuclease 8-like 1", "gene_name": "Neil1", "organism": "Hamster", "refseq_name": "endonuclease 8-like 1 isoform X1", "refseq_ac": [ { "id": "XP_027270799", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270799", "type": "external" } ], "gene_names_uniprotkb": "Neil1", "gene_names_refseq": "Neil1", "protein_names_uniprotkb": "Endonuclease 8-like 1; 4.2.99.18; DNA glycosylase/AP lyase Neil1; DNA-(apurinic or apyrimidinic site) lyase Neil1; Endonuclease VIII-like 1; Nei homolog 1; Nei-like protein 1", "protein_names_refseq": "endonuclease 8-like 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100762109)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as a DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, formamidopyrimidine (Fapy) and 5-hydroxyuracil. Has marginal activity towards 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. Has DNA glycosylase/lyase activity towards mismatched uracil and thymine, in particular in U:C and T:C mismatches. Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003684 damaged DNA binding;GO:0019104 DNA N-glycosylase activity;GO:0140078 class I DNA-(apurinic or apyrimidinic site) endonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0005694 chromosome", "go_biological_process": "GO:0006284 base-excision repair", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FWS5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FWU4-1", "uniprot_id": [ { "id": "A0A9J7FWU4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FWU4", "type": "external" } ], "mass": 38115.0, "length": 338, "protein_name": "Replication factor C subunit 5", "gene_name": "Rfc5", "organism": "Hamster", "refseq_name": "replication factor C subunit 5 isoform X1", "refseq_ac": [ { "id": "XP_027269986", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269986", "type": "external" } ], "gene_names_uniprotkb": "Rfc5", "gene_names_refseq": "Rfc5", "protein_names_uniprotkb": "Replication factor C subunit 5; Activator 1 36 kDa subunit; Activator 1 subunit 5; Replication factor C 36 kDa subunit", "protein_names_refseq": "replication factor C subunit 5 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100753174)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Subunit of the replication factor C (RFC) complex which acts during elongation of primed DNA templates by DNA polymerases delta and epsilon, and is necessary for ATP-dependent loading of proliferating cell nuclear antigen (PCNA) onto primed DNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003689 DNA clamp loader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005663 DNA replication factor C complex", "go_biological_process": "GO:0006281 DNA repair;GO:0006261 DNA-templated DNA replication", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FWU4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FX75-1", "uniprot_id": [ { "id": "A0A9J7FX75_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FX75", "type": "external" } ], "mass": 285809.0, "length": 2537, "protein_name": "Histone-lysine N-methyltransferase SETD2", "gene_name": "Setd2", "organism": "Hamster", "refseq_name": "histone-lysine N-methyltransferase SETD2 isoform X4", "refseq_ac": [ { "id": "XP_027270485", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270485", "type": "external" } ], "gene_names_uniprotkb": "Setd2", "gene_names_refseq": "Setd2", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase SETD2; 2.1.1.359; Lysine N-methyltransferase 3A; Protein-lysine N-methyltransferase SETD2; SET domain-containing protein 2", "protein_names_refseq": "histone-lysine N-methyltransferase SETD2 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100765637)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" }, { "id": "2.1.1.359", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.359", "type": "external" }, { "id": "2.1.1.367", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.367", "type": "external" }, { "id": "2.1.1.372", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.372", "type": "external" }, { "id": "2.1.1.361", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.361", "type": "external" }, { "id": "2.1.1.364", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.364", "type": "external" }, { "id": "2.1.1.355", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.355", "type": "external" }, { "id": "2.1.1.354", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.354", "type": "external" }, { "id": "2.1.1.362", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.362", "type": "external" }, { "id": "3.4.24.71", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.71", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0140955 histone H3K36 trimethyltransferase activity;GO:0043014 alpha-tubulin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:0006281 DNA repair;GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0045087 innate immune response;GO:0051607 defense response to virus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FX75-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FX78-1", "uniprot_id": [ { "id": "A0A9J7FX78_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FX78", "type": "external" } ], "mass": 34910.0, "length": 303, "protein_name": "Protein SET", "gene_name": "LOC100758661", "organism": "Hamster", "refseq_name": "protein SET isoform X2", "refseq_ac": [ { "id": "XP_027268803", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268803", "type": "external" } ], "gene_names_uniprotkb": "LOC100758661", "gene_names_refseq": "LOC100758661", "protein_names_uniprotkb": "Protein SET; Phosphatase 2A inhibitor I2PP2A; Template-activating factor I", "protein_names_refseq": "protein SET isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100758661)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Multitasking protein, involved in apoptosis, transcription, nucleosome assembly and histone chaperoning. Isoform 2 anti-apoptotic activity is mediated by inhibition of the GZMA-activated DNase, NME1. In the course of cytotoxic T-lymphocyte (CTL)-induced apoptosis, GZMA cleaves SET, disrupting its binding to NME1 and releasing NME1 inhibition. Isoform 1 and isoform 2 are potent inhibitors of protein phosphatase 2A. Isoform 1 and isoform 2 inhibit EP300/CREBBP and PCAF-mediated acetylation of histones (HAT) and nucleosomes, most probably by masking the accessibility of lysines of histones to the acetylases. The predominant target for inhibition is histone H4. HAT inhibition leads to silencing of HAT-dependent transcription and prevents active demethylation of DNA. Both isoforms stimulate DNA replication of the adenovirus genome complexed with viral core proteins; however, isoform 2 specific activity is higher., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006334 nucleosome assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FX78-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FXD0-1", "uniprot_id": [ { "id": "A0A9J7FXD0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FXD0", "type": "external" } ], "mass": 49495.0, "length": 448, "protein_name": "Protein phosphatase 1F", "gene_name": "Ppm1f", "organism": "Hamster", "refseq_name": "protein phosphatase 1F", "refseq_ac": [ { "id": "XP_027269019", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269019", "type": "external" } ], "gene_names_uniprotkb": "Ppm1f", "gene_names_refseq": "Ppm1f", "protein_names_uniprotkb": "Protein phosphatase 1F; 3.1.3.16; Ca(2+)/calmodulin-dependent protein kinase phosphatase", "protein_names_refseq": "protein phosphatase 1F", "tax_id": 10029, "disease": "", "pathway": " (cge:100758939)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Dephosphorylates and concomitantly deactivates CaM-kinase II activated upon autophosphorylation, and CaM-kinases IV and I activated upon phosphorylation by CaM-kinase kinase. Promotes apoptosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.52", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.52", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.74", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.74", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FXD0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FXE4-1", "uniprot_id": [ { "id": "A0A9J7FXE4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FXE4", "type": "external" } ], "mass": 36996.0, "length": 343, "protein_name": "exodeoxyribonuclease III", "gene_name": "Trex1", "organism": "Hamster", "refseq_name": "three-prime repair exonuclease 1 isoform X1", "refseq_ac": [ { "id": "XP_003504288", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504288", "type": "external" } ], "gene_names_uniprotkb": "Trex1", "gene_names_refseq": "Trex1", "protein_names_uniprotkb": "exodeoxyribonuclease III; 3.1.11.2", "protein_names_refseq": "three-prime repair exonuclease 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100761854)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614047.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003504288.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0046872 metal ion binding;GO:0008311 double-stranded DNA 3'-5' DNA exonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006281 DNA repair;GO:0006308 DNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FXE4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FXG6-1", "uniprot_id": [ { "id": "A0A9J7FXG6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FXG6", "type": "external" } ], "mass": 53839.0, "length": 496, "protein_name": "ADP-dependent glucokinase", "gene_name": "Adpgk", "organism": "Hamster", "refseq_name": "ADP-dependent glucokinase isoform X1", "refseq_ac": [ { "id": "XP_027270698", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270698", "type": "external" } ], "gene_names_uniprotkb": "Adpgk", "gene_names_refseq": "Adpgk", "protein_names_uniprotkb": "ADP-dependent glucokinase; 2.7.1.147", "protein_names_refseq": "ADP-dependent glucokinase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100754978)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.147", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.147", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0043843 ADP-specific glucokinase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0006006 glucose metabolic process;GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FXG6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FXI2-1", "uniprot_id": [ { "id": "A0A9J7FXI2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FXI2", "type": "external" } ], "mass": 101309.0, "length": 877, "protein_name": "ATP-dependent RNA helicase", "gene_name": "Ddx10", "organism": "Hamster", "refseq_name": "probable ATP-dependent RNA helicase DDX10 isoform X1", "refseq_ac": [ { "id": "XP_027270900", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270900", "type": "external" } ], "gene_names_uniprotkb": "Ddx10", "gene_names_refseq": "Ddx10", "protein_names_uniprotkb": "ATP-dependent RNA helicase; 3.6.4.13", "protein_names_refseq": "probable ATP-dependent RNA helicase DDX10 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100752733)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Putative ATP-dependent RNA helicase that plays various role in innate immunity or inflammation. Plays a role in the enhancement of AIM2-induced inflammasome activation by interacting with AIM2 and stabilizing its protein level. Negatively regulates viral infection by promoting interferon beta production and interferon stimulated genes/ISGs expression., [UniProtKB, UniProtKB, UniProtKB]; RNA helicase., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003724 RNA helicase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FXI2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GD77-1", "uniprot_id": [ { "id": "A0A9J7GD77_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GD77", "type": "external" } ], "mass": 88312.0, "length": 808, "protein_name": "Rho GTPase-activating protein 44", "gene_name": "Arhgap44", "organism": "Hamster", "refseq_name": "rho GTPase-activating protein 44 isoform X2", "refseq_ac": [ { "id": "XP_027282948", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282948", "type": "external" } ], "gene_names_uniprotkb": "Arhgap44", "gene_names_refseq": "Arhgap44", "protein_names_uniprotkb": "Rho GTPase-activating protein 44; Rho-type GTPase-activating protein RICH2; RhoGAP interacting with CIP4 homologs protein 2", "protein_names_refseq": "rho GTPase-activating protein 44 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772129)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; GTPase-activating protein (GAP) that stimulates the GTPase activity of Rho-type GTPases. Thereby, controls Rho-type GTPases cycling between their active GTP-bound and inactive GDP-bound states. Acts as a GAP at least for CDC42 and RAC1. In neurons, is involved in dendritic spine formation and synaptic plasticity in a specific RAC1-GAP activity. Limits the initiation of exploratory dendritic filopodia. Recruited to actin-patches that seed filopodia, binds specifically to plasma membrane sections that are deformed inward by acto-myosin mediated contractile forces. Acts through GAP activity on RAC1 to reduce actin polymerization necessary for filopodia formation. In association with SHANK3, promotes GRIA1 exocytosis from recycling endosomes and spine morphological changes associated to long-term potentiation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0014069 postsynaptic density;GO:0043197 dendritic spine;GO:0055037 recycling endosome;GO:0048786 presynaptic active zone;GO:0031256 leading edge membrane", "go_biological_process": "GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane;GO:0007165 signal transduction;GO:0032956 regulation of actin cytoskeleton organization;GO:0061001 regulation of dendritic spine morphogenesis;GO:0035021 negative regulation of Rac protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GD77-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GB63-1", "uniprot_id": [ { "id": "A0A9J7GB63_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GB63", "type": "external" } ], "mass": 37707.0, "length": 342, "protein_name": "Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6", "gene_name": "St6galnac6", "organism": "Hamster", "refseq_name": "alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform X4", "refseq_ac": [ { "id": "XP_027279595", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279595", "type": "external" } ], "gene_names_uniprotkb": "St6galnac6", "gene_names_refseq": "St6galnac6", "protein_names_uniprotkb": "Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6; GalNAc alpha-2,6-sialyltransferase VI; ST6GalNAc VI; Sialyltransferase 7F", "protein_names_refseq": "alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100757138)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.3.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.3.7", "type": "external" } ], "go_molecular_function": "GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0009101 glycoprotein biosynthetic process;GO:0009311 oligosaccharide metabolic process;GO:0001574 ganglioside biosynthetic process;GO:0009988 cell-cell recognition", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GB63-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G2N1-1", "uniprot_id": [ { "id": "A0A9J7G2N1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G2N1", "type": "external" } ], "mass": 47906.0, "length": 446, "protein_name": "Replication stress response regulator SDE2", "gene_name": "Sde2", "organism": "Hamster", "refseq_name": "replication stress response regulator SDE2 isoform X2", "refseq_ac": [ { "id": "XP_027274633", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274633", "type": "external" } ], "gene_names_uniprotkb": "Sde2", "gene_names_refseq": "Sde2", "protein_names_uniprotkb": "Replication stress response regulator SDE2", "protein_names_refseq": "replication stress response regulator SDE2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100752836)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Inhibits translesion DNA synthesis by preventing monoubiquitination of PCNA, this is necessary to counteract damage due to ultraviolet light-induced replication stress. SDE2 is cleaved following PCNA binding, and its complete degradation is necessary to allow S-phase progression following DNA damage., [UniProtKB, UniProtKB, UniProtKB]; Plays a role in pre-mRNA splicing by facilitating excision of relatively short introns featuring weak 3'-splice sites (ss) and high GC content. May recruit CACTIN to the spliceosome., [UniProtKB, UniProtKB, UniProtKB]; Plays a role in ribosome biogenesis by enabling SNORD3- and SNORD118-dependent cleavage of the 47S rRNA precursor. Binds ncRNA (non-coding RNA) including the snoRNAs SNORD3 and SNORD118., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003684 damaged DNA binding;GO:0030515 snoRNA binding;GO:0003677 DNA binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0016607 nuclear speck;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0016485 protein processing;GO:0051301 cell division;GO:0006260 DNA replication;GO:0016567 protein ubiquitination;GO:0034644 cellular response to UV", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G2N1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G1P3-1", "uniprot_id": [ { "id": "A0A9J7G1P3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G1P3", "type": "external" } ], "mass": 55435.0, "length": 514, "protein_name": "Runt-related transcription factor", "gene_name": "Runx1", "organism": "Hamster", "refseq_name": "runt-related transcription factor 1 isoform X8", "refseq_ac": [ { "id": "XP_027271425", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271425", "type": "external" } ], "gene_names_uniprotkb": "Runx1", "gene_names_refseq": "Runx1", "protein_names_uniprotkb": "Runt-related transcription factor", "protein_names_refseq": "runt-related transcription factor 1 isoform X8", "tax_id": 10029, "disease": "", "pathway": " (cge:100758283)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0016513 core-binding factor complex;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0030182 neuron differentiation;GO:0030097 hemopoiesis;GO:0045595 regulation of cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G1P3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FYJ1-1", "uniprot_id": [ { "id": "A0A9J7FYJ1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FYJ1", "type": "external" } ], "mass": 258324.0, "length": 2300, "protein_name": "Bromodomain and WD repeat-containing protein 1", "gene_name": "Brwd1", "organism": "Hamster", "refseq_name": "bromodomain and WD repeat-containing protein 1 isoform X4", "refseq_ac": [ { "id": "XP_027271486", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271486", "type": "external" } ], "gene_names_uniprotkb": "Brwd1", "gene_names_refseq": "Brwd1", "protein_names_uniprotkb": "Bromodomain and WD repeat-containing protein 1; WD repeat-containing protein 9", "protein_names_refseq": "bromodomain and WD repeat-containing protein 1 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100750709)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be a transcriptional activator. May be involved in chromatin remodeling. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005654 nucleoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007010 cytoskeleton organization;GO:0008360 regulation of cell shape", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FYJ1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FZA1-1", "uniprot_id": [ { "id": "A0A9J7FZA1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FZA1", "type": "external" } ], "mass": 65402.0, "length": 562, "protein_name": "E3 ubiquitin-protein ligase ARIH2", "gene_name": "Arih2", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase ARIH2 isoform X1", "refseq_ac": [ { "id": "XP_027240163", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240163", "type": "external" } ], "gene_names_uniprotkb": "Arih2", "gene_names_refseq": "Arih2", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase ARIH2; 2.3.2.31; Triad1 protein", "protein_names_refseq": "E3 ubiquitin-protein ligase ARIH2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100764705)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615379.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0031624 ubiquitin conjugating enzyme binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0031466 Cul5-RING ubiquitin ligase complex;GO:0005634 nucleus", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0070936 protein K48-linked ubiquitination;GO:0070534 protein K63-linked ubiquitination;GO:0071425 hematopoietic stem cell proliferation;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FZA1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G9G2-1", "uniprot_id": [ { "id": "A0A9J7G9G2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G9G2", "type": "external" } ], "mass": 147556.0, "length": 1334, "protein_name": "C-Jun-amino-terminal kinase-interacting protein 4", "gene_name": "Spag9", "organism": "Hamster", "refseq_name": "C-Jun-amino-terminal kinase-interacting protein 4 isoform X4", "refseq_ac": [ { "id": "XP_027280123", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280123", "type": "external" } ], "gene_names_uniprotkb": "Spag9", "gene_names_refseq": "Spag9", "protein_names_uniprotkb": "C-Jun-amino-terminal kinase-interacting protein 4; JNK-associated leucine-zipper protein; Mitogen-activated protein kinase 8-interacting protein 4; Sperm-associated antigen 9", "protein_names_refseq": "C-Jun-amino-terminal kinase-interacting protein 4 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100766397)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Regulates lysosomal positioning by acting as an adapter protein which links PIP4P1-positive lysosomes to the dynein-dynactin complex. Assists PIKFYVE selective functionality in microtubule-based endosome-to-TGN trafficking., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019894 kinesin binding;GO:0005078 MAP-kinase scaffold activity;GO:0016301 kinase activity;GO:0030159 signaling receptor complex adaptor activity;GO:0008432 JUN kinase binding", "go_cellular_component": "GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm;GO:0005765 lysosomal membrane;GO:0005737 cytoplasm;GO:0034451 centriolar satellite", "go_biological_process": "GO:0016192 vesicle-mediated transport;GO:0043408 regulation of MAPK cascade;GO:0030335 positive regulation of cell migration;GO:0032418 lysosome localization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G9G2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G757-1", "uniprot_id": [ { "id": "A0A9J7G757_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G757", "type": "external" } ], "mass": 85773.0, "length": 755, "protein_name": "Gamma-tubulin complex component", "gene_name": "Tubgcp4", "organism": "Hamster", "refseq_name": "gamma-tubulin complex component 4 isoform X8", "refseq_ac": [ { "id": "XP_027277867", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277867", "type": "external" } ], "gene_names_uniprotkb": "Tubgcp4", "gene_names_refseq": "Tubgcp4", "protein_names_uniprotkb": "Gamma-tubulin complex component", "protein_names_refseq": "gamma-tubulin complex component 4 isoform X8", "tax_id": 10029, "disease": "", "pathway": " (cge:100768027)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation. The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051011 microtubule minus-end binding;GO:0043015 gamma-tubulin binding", "go_cellular_component": "GO:0000922 spindle pole;GO:0005813 centrosome;GO:0005874 microtubule;GO:0000930 gamma-tubulin complex", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0007020 microtubule nucleation;GO:0051225 spindle assembly;GO:0051321 meiotic cell cycle;GO:0031122 cytoplasmic microtubule organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G757-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G9H9-1", "uniprot_id": [ { "id": "A0A9J7G9H9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G9H9", "type": "external" } ], "mass": 81613.0, "length": 726, "protein_name": "Propionate--CoA ligase", "gene_name": "Acss2", "organism": "Hamster", "refseq_name": "acetyl-coenzyme A synthetase, cytoplasmic isoform X1", "refseq_ac": [ { "id": "XP_016830467", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016830467", "type": "external" } ], "gene_names_uniprotkb": "Acss2", "gene_names_refseq": "Acss2", "protein_names_uniprotkb": "Propionate--CoA ligase; 6.2.1.17; 6.2.1.1", "protein_names_refseq": "acetyl-coenzyme A synthetase, cytoplasmic isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100752902)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613833.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.2.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.1", "type": "external" }, { "id": "6.2.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.17", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0003987 acetate-CoA ligase activity;GO:0050218 propionate-CoA ligase activity;GO:0016208 AMP binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005737 cytoplasm", "go_biological_process": "GO:0008610 lipid biosynthetic process;GO:0006085 acetyl-CoA biosynthetic process;GO:0006629 lipid metabolic process;GO:0019427 acetyl-CoA biosynthetic process from acetate", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G9H9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FZ33-1", "uniprot_id": [ { "id": "A0A9J7FZ33_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FZ33", "type": "external" } ], "mass": 76981.0, "length": 697, "protein_name": "tRNA-dihydrouridine(47) synthase [NAD(P)(+)]", "gene_name": "Dus3l", "organism": "Hamster", "refseq_name": "tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like isoform X1", "refseq_ac": [ { "id": "XP_007640620", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640620", "type": "external" } ], "gene_names_uniprotkb": "Dus3l", "gene_names_refseq": "Dus3l", "protein_names_uniprotkb": "tRNA-dihydrouridine(47) synthase [NAD(P)(+)]; 1.3.1.-; tRNA-dihydrouridine synthase 3", "protein_names_refseq": "tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100760481)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613861.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the synthesis of dihydrouridine, a modified base, in various RNAs, such as tRNAs, mRNAs and some long non-coding RNAs (lncRNAs). Mainly modifies the uridine in position 47 (U47) in the D-loop of most cytoplasmic tRNAs. Also able to mediate the formation of dihydrouridine in some mRNAs, thereby regulating their translation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.-", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0008270 zinc ion binding;GO:0050660 flavin adenine dinucleotide binding;GO:0106414 mRNA dihydrouridine synthase activity;GO:0102265 tRNA-dihydrouridine47 synthase activity", "go_cellular_component": "", "go_biological_process": "GO:0006397 mRNA processing;GO:0006417 regulation of translation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FZ33-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FYN8-1", "uniprot_id": [ { "id": "A0A9J7FYN8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FYN8", "type": "external" } ], "mass": 227278.0, "length": 2005, "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "Ttc3", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase TTC3 isoform X1", "refseq_ac": [ { "id": "XP_016833913", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016833913", "type": "external" } ], "gene_names_uniprotkb": "Ttc3", "gene_names_refseq": "Ttc3", "protein_names_uniprotkb": "RING-type E3 ubiquitin transferase; 2.3.2.27", "protein_names_refseq": "E3 ubiquitin-protein ligase TTC3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100750887)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614462.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; E3 ubiquitin-protein ligase which catalyzes the formation of 'Lys-48'-polyubiquitin chains. Mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation; its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Positively regulates TGFB1-induced epithelial-mesenchymal transition and myofibroblast differentiation by mediating the ubiquitination and subsequent degradation of SMURF2. Regulates neuronal differentiation by regulating actin remodeling and Golgi organization via a signaling cascade involving RHOA, CIT and ROCK. Inhibits cell proliferation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005794 Golgi apparatus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006511 ubiquitin-dependent protein catabolic process;GO:0070936 protein K48-linked ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FYN8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G3B3-1", "uniprot_id": [ { "id": "A0A9J7G3B3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G3B3", "type": "external" } ], "mass": 185434.0, "length": 1736, "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-79 specific", "gene_name": "Dot1l", "organism": "Hamster", "refseq_name": "histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X2", "refseq_ac": [ { "id": "XP_027275106", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275106", "type": "external" } ], "gene_names_uniprotkb": "Dot1l", "gene_names_refseq": "Dot1l", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase, H3 lysine-79 specific", "protein_names_refseq": "histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100771005)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Histone methyltransferase. Methylates 'Lys-79' of histone H3., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0140956 histone H3K79 trimethyltransferase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0032991 protein-containing complex;GO:0005634 nucleus", "go_biological_process": "GO:0046425 regulation of receptor signaling pathway via JAK-STAT;GO:0006281 DNA repair;GO:0032259 methylation;GO:0000077 DNA damage checkpoint signaling;GO:0031507 heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G3B3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FZM5-1", "uniprot_id": [ { "id": "A0A9J7FZM5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FZM5", "type": "external" } ], "mass": 151084.0, "length": 1323, "protein_name": "Lysine-specific demethylase 2B", "gene_name": "Kdm2b", "organism": "Hamster", "refseq_name": "lysine-specific demethylase 2B isoform X4", "refseq_ac": [ { "id": "XP_027269814", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269814", "type": "external" } ], "gene_names_uniprotkb": "Kdm2b", "gene_names_refseq": "Kdm2b", "protein_names_uniprotkb": "Lysine-specific demethylase 2B; 1.14.11.27; F-box and leucine-rich repeat protein 10; F-box protein FBL10; F-box/LRR-repeat protein 10; JmjC domain-containing histone demethylation protein 1B; [Histone-H3]-lysine-36 demethylase 1B", "protein_names_refseq": "lysine-specific demethylase 2B isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100767158)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Histone demethylase that demethylates 'Lys-4' and 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' and dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.27", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.27", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0019843 rRNA binding;GO:0043565 sequence-specific DNA binding;GO:0140680 histone H3K36me/H3K36me2 demethylase activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005694 chromosome;GO:0005654 nucleoplasm;GO:0031519 PcG protein complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0001843 neural tube closure;GO:0021555 midbrain-hindbrain boundary morphogenesis;GO:0021592 fourth ventricle development;GO:0021993 initiation of neural tube closure", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FZM5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G003-1", "uniprot_id": [ { "id": "A0A9J7G003_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G003", "type": "external" } ], "mass": 213185.0, "length": 1920, "protein_name": "Receptor-type tyrosine-protein phosphatase S", "gene_name": "Ptprs", "organism": "Hamster", "refseq_name": "receptor-type tyrosine-protein phosphatase S isoform X2", "refseq_ac": [ { "id": "XP_027272641", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272641", "type": "external" } ], "gene_names_uniprotkb": "Ptprs", "gene_names_refseq": "Ptprs", "protein_names_uniprotkb": "Receptor-type tyrosine-protein phosphatase S; 3.1.3.48; Receptor-type tyrosine-protein phosphatase sigma", "protein_names_refseq": "receptor-type tyrosine-protein phosphatase S isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100770533)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" } ], "go_molecular_function": "GO:0008201 heparin binding;GO:0004725 protein tyrosine phosphatase activity;GO:0035374 chondroitin sulfate binding", "go_cellular_component": "GO:0014069 postsynaptic density;GO:0030426 growth cone;GO:0043204 perikaryon;GO:0030672 synaptic vesicle membrane;GO:0042734 presynaptic membrane", "go_biological_process": "GO:0099151 regulation of postsynaptic density assembly;GO:0050804 modulation of chemical synaptic transmission;GO:0061000 negative regulation of dendritic spine development;GO:0032688 negative regulation of interferon-beta production;GO:0099560 synaptic membrane adhesion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G003-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GE19-1", "uniprot_id": [ { "id": "A0A9J7GE19_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GE19", "type": "external" } ], "mass": 87921.0, "length": 764, "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "Smurf2", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase SMURF2 isoform X1", "refseq_ac": [ { "id": "XP_003501922", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501922", "type": "external" } ], "gene_names_uniprotkb": "Smurf2", "gene_names_refseq": "Smurf2", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase; 2.3.2.26", "protein_names_refseq": "E3 ubiquitin-protein ligase SMURF2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100773704)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613864.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0061630 ubiquitin protein ligase activity;GO:0046332 SMAD binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0016607 nuclear speck;GO:0045121 membrane raft;GO:0000151 ubiquitin ligase complex", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0030514 negative regulation of BMP signaling pathway;GO:0016567 protein ubiquitination;GO:1901165 positive regulation of trophoblast cell migration;GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GE19-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G9V0-1", "uniprot_id": [ { "id": "A0A9J7G9V0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G9V0", "type": "external" } ], "mass": 142245.0, "length": 1296, "protein_name": "[histone H3]-lysine(9) N-methyltransferase", "gene_name": "Ehmt1", "organism": "Hamster", "refseq_name": "histone-lysine N-methyltransferase EHMT1 isoform X10", "refseq_ac": [ { "id": "XP_027278590", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278590", "type": "external" } ], "gene_names_uniprotkb": "Ehmt1", "gene_names_refseq": "Ehmt1", "protein_names_uniprotkb": "[histone H3]-lysine(9) N-methyltransferase; 2.1.1.367", "protein_names_refseq": "histone-lysine N-methyltransferase EHMT1 isoform X10", "tax_id": 10029, "disease": "", "pathway": " (cge:100754544)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.366", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.366", "type": "external" }, { "id": "2.1.1.359", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.359", "type": "external" }, { "id": "2.1.1.367", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.367", "type": "external" }, { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0002039 p53 binding;GO:0046976 histone H3K27 methyltransferase activity;GO:0070742 C2H2 zinc finger domain binding;GO:0140948 histone H3K9 monomethyltransferase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0000785 chromatin;GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0032259 methylation;GO:0006346 DNA methylation-dependent constitutive heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G9V0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FY79-1", "uniprot_id": [ { "id": "A0A9J7FY79_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FY79", "type": "external" } ], "mass": 125018.0, "length": 1091, "protein_name": "Dynamin-like GTPase OPA1, mitochondrial", "gene_name": "Opa1", "organism": "Hamster", "refseq_name": "dynamin-like 120 kDa protein, mitochondrial isoform X1", "refseq_ac": [ { "id": "XP_027268715", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268715", "type": "external" } ], "gene_names_uniprotkb": "Opa1", "gene_names_refseq": "Opa1", "protein_names_uniprotkb": "Dynamin-like GTPase OPA1, mitochondrial; 3.6.5.5", "protein_names_refseq": "dynamin-like 120 kDa protein, mitochondrial isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100751873)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Isoforms that contain the alternative exon 4b are required for mitochondrial genome maintenance, possibly by anchoring the mitochondrial nucleoids to the inner mitochondrial membrane., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0008017 microtubule binding;GO:0008289 lipid binding;GO:0070300 phosphatidic acid binding", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005758 mitochondrial intermembrane space;GO:0005874 microtubule;GO:0005741 mitochondrial outer membrane;GO:0030425 dendrite", "go_biological_process": "GO:0006897 endocytosis;GO:0016559 peroxisome fission;GO:0006915 apoptotic process;GO:0008053 mitochondrial fusion;GO:0010821 regulation of mitochondrion organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FY79-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G7F1-1", "uniprot_id": [ { "id": "A0A9J7G7F1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G7F1", "type": "external" } ], "mass": 90595.0, "length": 796, "protein_name": "RAS guanyl-releasing protein 1", "gene_name": "Rasgrp1", "organism": "Hamster", "refseq_name": "RAS guanyl-releasing protein 1 isoform X2", "refseq_ac": [ { "id": "XP_027278032", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278032", "type": "external" } ], "gene_names_uniprotkb": "Rasgrp1", "gene_names_refseq": "Rasgrp1", "protein_names_uniprotkb": "RAS guanyl-releasing protein 1; Calcium and DAG-regulated guanine nucleotide exchange factor II; Ras guanyl-releasing protein", "protein_names_refseq": "RAS guanyl-releasing protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762037)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Functions as a calcium- and diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. Activates the Erk/MAP kinase cascade. Regulates T-cell/B-cell development, homeostasis and differentiation by coupling T-lymphocyte/B-lymphocyte antigen receptors to Ras. Regulates NK cell cytotoxicity and ITAM-dependent cytokine production by activation of Ras-mediated ERK and JNK pathways. Functions in mast cell degranulation and cytokine secretion, regulating FcERI-evoked allergic responses. May also function in differentiation of other cell types. Proto-oncogene, which promotes T-cell lymphomagenesis when its expression is deregulated., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0005509 calcium ion binding;GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0030154 cell differentiation;GO:0007265 Ras protein signal transduction;GO:1902531 regulation of intracellular signal transduction;GO:0002684 positive regulation of immune system process;GO:0045321 leukocyte activation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G7F1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FYM8-1", "uniprot_id": [ { "id": "A0A9J7FYM8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FYM8", "type": "external" } ], "mass": 98167.0, "length": 877, "protein_name": "ATP-dependent RNA helicase DDX54", "gene_name": "Ddx54", "organism": "Hamster", "refseq_name": "ATP-dependent RNA helicase DDX54 isoform X1", "refseq_ac": [ { "id": "XP_027269938", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269938", "type": "external" } ], "gene_names_uniprotkb": "Ddx54", "gene_names_refseq": "Ddx54", "protein_names_uniprotkb": "ATP-dependent RNA helicase DDX54; 3.6.4.13; DEAD box protein 54", "protein_names_refseq": "ATP-dependent RNA helicase DDX54 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100770376)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0005102 signaling receptor binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003714 transcription corepressor activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0005829 cytosol", "go_biological_process": "GO:0006396 RNA processing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FYM8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G7G9-1", "uniprot_id": [ { "id": "A0A9J7G7G9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G7G9", "type": "external" } ], "mass": 182877.0, "length": 1646, "protein_name": "MAP kinase-activating death domain protein", "gene_name": "Madd", "organism": "Hamster", "refseq_name": "MAP kinase-activating death domain protein isoform X51", "refseq_ac": [ { "id": "XP_027278340", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278340", "type": "external" } ], "gene_names_uniprotkb": "Madd", "gene_names_refseq": "Madd", "protein_names_uniprotkb": "MAP kinase-activating death domain protein; Rab3 GDP/GTP exchange factor; Rab3 GDP/GTP exchange protein", "protein_names_refseq": "MAP kinase-activating death domain protein isoform X51", "tax_id": 10029, "disease": "", "pathway": " (cge:100757666)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Guanyl-nucleotide exchange factor that regulates small GTPases of the Rab family. Converts GDP-bound inactive form of RAB27A and RAB27B to the GTP-bound active forms. Converts GDP-bound inactive form of RAB3A, RAB3C and RAB3D to the GTP-bound active forms, GTPases involved in synaptic vesicle exocytosis and vesicle secretion. Plays a role in synaptic vesicle formation and in vesicle trafficking at the neuromuscular junction. Involved in up-regulating a post-docking step of synaptic exocytosis in central synapses. Probably by binding to the motor proteins KIF1B and KIF1A, mediates motor-dependent transport of GTP-RAB3A-positive vesicles to the presynaptic nerve terminals. Plays a role in TNFA-mediated activation of the MAPK pathway, including ERK1/2. May link TNFRSF1A with MAP kinase activation. May be involved in the regulation of TNFA-induced apoptosis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity;GO:0016301 kinase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0032483 regulation of Rab protein signal transduction;GO:0006915 apoptotic process;GO:0042981 regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G7G9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GES8-1", "uniprot_id": [ { "id": "A0A9J7GES8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GES8", "type": "external" } ], "mass": 87134.0, "length": 766, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Tlk2", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase tousled-like 2 isoform X1", "refseq_ac": [ { "id": "XP_016831349", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831349", "type": "external" } ], "gene_names_uniprotkb": "Tlk2", "gene_names_refseq": "Tlk2", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase tousled-like 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100771294)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613926.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0007059 chromosome segregation;GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GES8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G261-1", "uniprot_id": [ { "id": "A0A9J7G261_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G261", "type": "external" } ], "mass": 42074.0, "length": 384, "protein_name": "Prostaglandin reductase 2", "gene_name": "Ptgr2", "organism": "Hamster", "refseq_name": "prostaglandin reductase 2 isoform X1", "refseq_ac": [ { "id": "XP_007643863", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643863", "type": "external" } ], "gene_names_uniprotkb": "Ptgr2", "gene_names_refseq": "Ptgr2", "protein_names_uniprotkb": "Prostaglandin reductase 2; 1.3.1.48; 15-oxoprostaglandin 13-reductase; Zinc-binding alcohol dehydrogenase domain-containing protein 1", "protein_names_refseq": "prostaglandin reductase 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100750573)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614123.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.3.1.74", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.74", "type": "external" }, { "id": "1.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.48", "type": "external" } ], "go_molecular_function": "GO:0047522 15-oxoprostaglandin 13-reductase [NAD(P)+] activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006693 prostaglandin metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G261-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G5B3-1", "uniprot_id": [ { "id": "A0A9J7G5B3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G5B3", "type": "external" } ], "mass": 34218.0, "length": 315, "protein_name": "Small glutamine-rich tetratricopeptide repeat-containing protein alpha", "gene_name": "Sgta", "organism": "Hamster", "refseq_name": "small glutamine-rich tetratricopeptide repeat-containing protein alpha isoform X1", "refseq_ac": [ { "id": "XP_007645166", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645166", "type": "external" } ], "gene_names_uniprotkb": "Sgta", "gene_names_refseq": "Sgta", "protein_names_uniprotkb": "Small glutamine-rich tetratricopeptide repeat-containing protein alpha; Alpha-SGT", "protein_names_refseq": "small glutamine-rich tetratricopeptide repeat-containing protein alpha isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100764968)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614244.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Co-chaperone that binds misfolded and hydrophobic patches-containing client proteins in the cytosol. Mediates their targeting to the endoplasmic reticulum but also regulates their sorting to the proteasome when targeting fails. Functions in tail-anchored/type II transmembrane proteins membrane insertion constituting with ASNA1 and the BAG6 complex a targeting module. Functions upstream of the BAG6 complex and ASNA1, binding more rapidly the transmembrane domain of newly synthesized proteins. It is also involved in the regulation of the endoplasmic reticulum-associated misfolded protein catabolic process via its interaction with BAG6: collaborates with the BAG6 complex to maintain hydrophobic substrates in non-ubiquitinated states. Competes with RNF126 for interaction with BAG6, preventing the ubiquitination of client proteins associated with the BAG6 complex. Binds directly to HSC70 and HSP70 and regulates their ATPase activity., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0042802 identical protein binding;GO:1904288 BAT3 complex binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0016020 membrane;GO:0072380 TRC complex;GO:0005634 nucleus", "go_biological_process": "GO:0006620 post-translational protein targeting to endoplasmic reticulum membrane;GO:0051260 protein homooligomerization;GO:0051291 protein heterooligomerization;GO:0036503 ERAD pathway;GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G5B3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G3N0-1", "uniprot_id": [ { "id": "A0A9J7G3N0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G3N0", "type": "external" } ], "mass": 30487.0, "length": 273, "protein_name": "E3 ubiquitin-protein ligase MARCHF2", "gene_name": "Marchf2", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase MARCHF2 isoform X1", "refseq_ac": [ { "id": "XP_007649320", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649320", "type": "external" } ], "gene_names_uniprotkb": "Marchf2", "gene_names_refseq": "Marchf2", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase MARCHF2; 2.3.2.27; Membrane-associated RING finger protein 2; Membrane-associated RING-CH protein II; RING-type E3 ubiquitin transferase MARCHF2", "protein_names_refseq": "E3 ubiquitin-protein ligase MARCHF2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100754256)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614895.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005886 plasma membrane;GO:0005765 lysosomal membrane;GO:0005789 endoplasmic reticulum membrane;GO:0010008 endosome membrane", "go_biological_process": "GO:0044790 suppression of viral release by host;GO:1905167 positive regulation of lysosomal protein catabolic process;GO:0006897 endocytosis;GO:0016567 protein ubiquitination;GO:0140374 antiviral innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G3N0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G720-1", "uniprot_id": [ { "id": "A0A9J7G720_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G720", "type": "external" } ], "mass": 49148.0, "length": 452, "protein_name": "Isovaleryl-CoA dehydrogenase, mitochondrial", "gene_name": "Ivd", "organism": "Hamster", "refseq_name": "isovaleryl-CoA dehydrogenase, mitochondrial isoform X2", "refseq_ac": [ { "id": "XP_027277992", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277992", "type": "external" } ], "gene_names_uniprotkb": "Ivd", "gene_names_refseq": "Ivd", "protein_names_uniprotkb": "Isovaleryl-CoA dehydrogenase, mitochondrial; 1.3.8.1; 1.3.8.4; Butyryl-CoA dehydrogenase", "protein_names_refseq": "isovaleryl-CoA dehydrogenase, mitochondrial isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100759847)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; A mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism, where isovaleryl-CoA (3-methylbutanoyl-CoA) is metabolized to 3-methylbut-2-enoyl-CoA. To a lesser extent, it also participates in the first step in fatty acid beta-oxidation, in which it catalyzes the proR-proR stereospecific alpha,beta-dehydrogenation of other saturated short-chain acyl-CoA thioesters such as pentanoyl-CoA, hexanoyl-CoA and butanoyl-CoA, using the electron transfer flavoprotein (ETF) as their physiologic electron acceptor., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.3.8.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.1", "type": "external" }, { "id": "1.3.8.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.5", "type": "external" }, { "id": "1.3.8.7", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.7", "type": "external" }, { "id": "1.3.8.8", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.8", "type": "external" }, { "id": "1.3.8.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.4", "type": "external" } ], "go_molecular_function": "GO:0008470 3-methylbutanoyl-CoA dehydrogenase activity;GO:0050660 flavin adenine dinucleotide binding", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006552 L-leucine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G720-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GBX8-1", "uniprot_id": [ { "id": "A0A9J7GBX8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GBX8", "type": "external" } ], "mass": 27757.0, "length": 244, "protein_name": "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "gene_name": "Ntmt1", "organism": "Hamster", "refseq_name": "N-terminal Xaa-Pro-Lys N-methyltransferase 1 isoform X1", "refseq_ac": [ { "id": "XP_027240960", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240960", "type": "external" } ], "gene_names_uniprotkb": "Ntmt1", "gene_names_refseq": "Ntmt1", "protein_names_uniprotkb": "N-terminal Xaa-Pro-Lys N-methyltransferase 1; 2.1.1.244; Alpha N-terminal protein methyltransferase 1A; Methyltransferase-like protein 11A; X-Pro-Lys N-terminal protein methyltransferase 1A", "protein_names_refseq": "N-terminal Xaa-Pro-Lys N-methyltransferase 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100771449)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616044.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Distributive alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Gly/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of the exposed alpha-amino group of the Ala, Gly or Ser residue in the [Ala/Gly/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Some of the substrates may be primed by NTMT2-mediated monomethylation. Catalyzes the trimethylation of the N-terminal Gly in CENPA (after removal of Met-1). Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on RCC1., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.244", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.244", "type": "external" } ], "go_molecular_function": "GO:0071885 N-terminal protein N-methyltransferase activity;GO:0042054 histone methyltransferase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0007059 chromosome segregation;GO:0032259 methylation;GO:0007051 spindle organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GBX8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GD94-1", "uniprot_id": [ { "id": "A0A9J7GD94_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GD94", "type": "external" } ], "mass": 213115.0, "length": 1945, "protein_name": "WD repeat-containing protein 81", "gene_name": "Wdr81", "organism": "Hamster", "refseq_name": "WD repeat-containing protein 81 isoform X1", "refseq_ac": [ { "id": "XP_007653317", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653317", "type": "external" } ], "gene_names_uniprotkb": "Wdr81", "gene_names_refseq": "Wdr81", "protein_names_uniprotkb": "WD repeat-containing protein 81", "protein_names_refseq": "WD repeat-containing protein 81 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100765687)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003617380.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Functions as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes via BECN1, a core subunit of the PI3K complex. By modifying the phosphatidylinositol 3-phosphate/PtdInsP3 content of endosomal membranes may regulate endosome fusion, recycling, sorting and early to late endosome transport. It is for instance, required for the delivery of cargos like BST2/tetherin from early to late endosome and thereby participates indirectly to their degradation by the lysosome. May also play a role in aggrephagy, the macroautophagic degradation of ubiquitinated protein aggregates. In this process, may regulate the interaction of SQSTM1 with ubiquitinated proteins and also recruit MAP1LC3C. May also be involved in maintenance of normal mitochondrial structure and organization., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0070530 K63-linked polyubiquitin modification-dependent protein binding;GO:0141039 phosphatidylinositol 3-kinase inhibitor activity;GO:0035014 phosphatidylinositol 3-kinase regulator activity", "go_cellular_component": "GO:0000421 autophagosome membrane;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane", "go_biological_process": "GO:0050821 protein stabilization;GO:0045022 early endosome to late endosome transport;GO:0007005 mitochondrion organization;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0035973 aggrephagy", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GD94-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G013-1", "uniprot_id": [ { "id": "A0A9J7G013_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G013", "type": "external" } ], "mass": 89144.0, "length": 792, "protein_name": "E3 ubiquitin-protein ligase UHRF", "gene_name": "Uhrf1", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase UHRF1 isoform X1", "refseq_ac": [ { "id": "XP_007640605", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640605", "type": "external" } ], "gene_names_uniprotkb": "Uhrf1", "gene_names_refseq": "Uhrf1", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase UHRF; 2.3.2.27; RING-type E3 ubiquitin transferase UHRF; Ubiquitin-like PHD and RING finger domain-containing protein; Ubiquitin-like-containing PHD and RING finger domains protein", "protein_names_refseq": "E3 ubiquitin-protein ligase UHRF1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100758459)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613861.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Multi domain E3 ubiquitin ligase that also plays a role in DNA methylation and histone modifications., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0042393 histone binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0016567 protein ubiquitination;GO:0044027 negative regulation of gene expression via chromosomal CpG island methylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G013-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FXR4-1", "uniprot_id": [ { "id": "A0A9J7FXR4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FXR4", "type": "external" } ], "mass": 38833.0, "length": 360, "protein_name": "CD276 antigen", "gene_name": "Cd276", "organism": "Hamster", "refseq_name": "CD276 antigen isoform X4", "refseq_ac": [ { "id": "XP_027270714", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270714", "type": "external" } ], "gene_names_uniprotkb": "Cd276", "gene_names_refseq": "Cd276", "protein_names_uniprotkb": "CD276 antigen; B7 homolog 3; Costimulatory molecule", "protein_names_refseq": "CD276 antigen isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100754397)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0042110 T cell activation;GO:0050852 T cell receptor signaling pathway;GO:0032729 positive regulation of type II interferon production;GO:0042102 positive regulation of T cell proliferation;GO:0001819 positive regulation of cytokine production", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FXR4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GC59-1", "uniprot_id": [ { "id": "A0A9J7GC59_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GC59", "type": "external" } ], "mass": 95228.0, "length": 826, "protein_name": "Volume-regulated anion channel subunit LRRC8C", "gene_name": "Lrrc8c", "organism": "Hamster", "refseq_name": "volume-regulated anion channel subunit LRRC8C isoform X1", "refseq_ac": [ { "id": "XP_016833025", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016833025", "type": "external" } ], "gene_names_uniprotkb": "Lrrc8c", "gene_names_refseq": "Lrrc8c", "protein_names_uniprotkb": "Volume-regulated anion channel subunit LRRC8C; Leucine-rich repeat-containing protein 8C", "protein_names_refseq": "volume-regulated anion channel subunit LRRC8C isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100765936)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614236.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" } ], "go_molecular_function": "GO:0005225 volume-sensitive anion channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane;GO:0034702 monoatomic ion channel complex", "go_biological_process": "GO:0034214 protein hexamerization;GO:0140361 cyclic-GMP-AMP transmembrane import across plasma membrane;GO:0034220 monoatomic ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GC59-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G026-1", "uniprot_id": [ { "id": "A0A9J7G026_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G026", "type": "external" } ], "mass": 137389.0, "length": 1238, "protein_name": "Calcium-transporting ATPase", "gene_name": "Atp2b4", "organism": "Hamster", "refseq_name": "plasma membrane calcium-transporting ATPase 4 isoform X3", "refseq_ac": [ { "id": "XP_016832759", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016832759", "type": "external" } ], "gene_names_uniprotkb": "Atp2b4", "gene_names_refseq": "Atp2b4", "protein_names_uniprotkb": "Calcium-transporting ATPase; 7.2.2.10", "protein_names_refseq": "plasma membrane calcium-transporting ATPase 4 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100764868)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614184.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the hydrolysis of ATP coupled with the transport of calcium., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "7.2.2.10", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.10", "type": "external" } ], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0030165 PDZ domain binding", "go_cellular_component": "GO:0045121 membrane raft;GO:0036126 sperm flagellum;GO:0030018 Z disc;GO:0030315 T-tubule;GO:0005886 plasma membrane", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0010629 negative regulation of gene expression;GO:0030317 flagellated sperm motility;GO:0051480 regulation of cytosolic calcium ion concentration;GO:0071878 negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G026-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G7M2-1", "uniprot_id": [ { "id": "A0A9J7G7M2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G7M2", "type": "external" } ], "mass": 47804.0, "length": 427, "protein_name": "P2X purinoceptor", "gene_name": "P2rx3", "organism": "Hamster", "refseq_name": "P2X purinoceptor 3 isoform X1", "refseq_ac": [ { "id": "XP_007644832", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644832", "type": "external" } ], "gene_names_uniprotkb": "P2rx3", "gene_names_refseq": "P2rx3", "protein_names_uniprotkb": "P2X purinoceptor; P2X purinoceptor 3", "protein_names_refseq": "P2X purinoceptor 3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100758483)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614216.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Extracellular ATP-activated non-selective cation channel. Plays particularly important role in sensory neurons where its activation is critical for gustatory, nociceptive responses, visceral reflexes and sensory hypersensitization., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Receptor for ATP that acts as a ligand-gated ion channel., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 1, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0001614 purinergic nucleotide receptor activity;GO:0004931 extracellularly ATP-gated monoatomic cation channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon;GO:0043235 receptor complex;GO:0098794 postsynapse;GO:0098686 hippocampal mossy fiber to CA3 synapse", "go_biological_process": "GO:0050804 modulation of chemical synaptic transmission;GO:0070207 protein homotrimerization;GO:0070588 calcium ion transmembrane transport;GO:0071318 cellular response to ATP;GO:0033198 response to ATP", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G7M2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GBN2-1", "uniprot_id": [ { "id": "A0A9J7GBN2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GBN2", "type": "external" } ], "mass": 50206.0, "length": 440, "protein_name": "Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6", "gene_name": "Jmjd6", "organism": "Hamster", "refseq_name": "bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 isoform X1", "refseq_ac": [ { "id": "XP_007632289", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007632289", "type": "external" } ], "gene_names_uniprotkb": "Jmjd6", "gene_names_refseq": "Jmjd6", "protein_names_uniprotkb": "Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6; Histone arginine demethylase JMJD6; JmjC domain-containing protein 6; Jumonji domain-containing protein 6; Lysyl-hydroxylase JMJD6; Peptide-lysine 5-dioxygenase JMJD6; Phosphatidylserine receptor", "protein_names_refseq": "bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100774658)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 204 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613705.1) and transcript sequence (JI893589.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0033746 histone H3R2 demethylase activity;GO:0033749 histone H4R3 demethylase activity;GO:0070815 peptidyl-lysine 5-dioxygenase activity;GO:0005506 iron ion binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006397 mRNA processing;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0051260 protein homooligomerization;GO:0006909 phagocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GBN2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G512-1", "uniprot_id": [ { "id": "A0A9J7G512_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G512", "type": "external" } ], "mass": 40181.0, "length": 353, "protein_name": "Ataxin-3", "gene_name": "Atxn3", "organism": "Hamster", "refseq_name": "ataxin-3 isoform X10", "refseq_ac": [ { "id": "XP_027274943", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274943", "type": "external" } ], "gene_names_uniprotkb": "Atxn3", "gene_names_refseq": "Atxn3", "protein_names_uniprotkb": "Ataxin-3; 3.4.19.12; Machado-Joseph disease protein 1 homolog", "protein_names_refseq": "ataxin-3 isoform X10", "tax_id": 10029, "disease": "", "pathway": " (cge:100754332)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Deubiquitinating enzyme involved in protein homeostasis maintenance, transcription, cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. Binds long polyubiquitin chains and trims them, while it has weak or no activity against chains of 4 or less ubiquitins. Involved in degradation of misfolded chaperone substrates via its interaction with STUB1/CHIP: recruited to monoubiquitinated STUB1/CHIP, and restricts the length of ubiquitin chain attached to STUB1/CHIP substrates and preventing further chain extension. Interacts with key regulators of transcription and represses transcription: acts as a histone-binding protein that regulates transcription. Acts as a negative regulator of mTORC1 signaling in response to amino acid deprivation by mediating deubiquitination of RHEB, thereby promoting RHEB inactivation by the TSC-TBC complex. Regulates autophagy via the deubiquitination of 'Lys-402' of BECN1 leading to the stabilization of BECN1., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051117 ATPase binding;GO:0031625 ubiquitin protein ligase binding;GO:0004843 cysteine-type deubiquitinase activity;GO:0061578 K63-linked deubiquitinase activity;GO:1990380 K48-linked deubiquitinase activity", "go_cellular_component": "GO:0005759 mitochondrial matrix;GO:0005829 cytosol;GO:0031966 mitochondrial membrane;GO:0005765 lysosomal membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0070536 protein K63-linked deubiquitination;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0034198 cellular response to amino acid starvation;GO:1904294 positive regulation of ERAD pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G512-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G776-1", "uniprot_id": [ { "id": "A0A9J7G776_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G776", "type": "external" } ], "mass": 25035.0, "length": 227, "protein_name": "Josephin-2", "gene_name": "Josd2", "organism": "Hamster", "refseq_name": "josephin-2 isoform X1", "refseq_ac": [ { "id": "XP_007649015", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649015", "type": "external" } ], "gene_names_uniprotkb": "Josd2", "gene_names_refseq": "Josd2", "protein_names_uniprotkb": "Josephin-2; 3.4.19.12; Josephin domain-containing protein 2", "protein_names_refseq": "josephin-2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100755892)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614844.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cleaves 'Lys-63'-linked poly-ubiquitin chains, and with lesser efficiency 'Lys-48'-linked poly-ubiquitin chains (in vitro). May act as a deubiquitinating enzyme., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006508 proteolysis;GO:0016579 protein deubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G776-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GDU6-1", "uniprot_id": [ { "id": "A0A9J7GDU6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GDU6", "type": "external" } ], "mass": 282453.0, "length": 2556, "protein_name": "Nuclear receptor corepressor 1", "gene_name": "Ncor1", "organism": "Hamster", "refseq_name": "nuclear receptor corepressor 1 isoform X2", "refseq_ac": [ { "id": "XP_027282981", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282981", "type": "external" } ], "gene_names_uniprotkb": "Ncor1", "gene_names_refseq": "Ncor1", "protein_names_uniprotkb": "Nuclear receptor corepressor 1", "protein_names_refseq": "nuclear receptor corepressor 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100760832)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Mediates transcriptional repression by certain nuclear receptors. Part of a complex which promotes histone deacetylation and the formation of repressive chromatin structures which may impede the access of basal transcription factors. Participates in the transcriptional repressor activity produced by BCL6. Recruited by ZBTB7A to the androgen response elements/ARE on target genes, negatively regulates androgen receptor signaling and androgen-induced cell proliferation. Mediates the NR1D1-dependent repression and circadian regulation of TSHB expression. The NCOR1-HDAC3 complex regulates the circadian expression of the core clock gene ARTNL/BMAL1 and the genes involved in lipid metabolism in the liver., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003714 transcription corepressor activity;GO:0046966 nuclear thyroid hormone receptor binding;GO:0003677 DNA binding", "go_cellular_component": "GO:0000785 chromatin;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0017053 transcription repressor complex;GO:0032991 protein-containing complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:1902532 negative regulation of intracellular signal transduction;GO:0001701 in utero embryonic development;GO:0006351 DNA-templated transcription;GO:0061436 establishment of skin barrier", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GDU6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GA42-1", "uniprot_id": [ { "id": "A0A9J7GA42_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GA42", "type": "external" } ], "mass": 56612.0, "length": 516, "protein_name": "Tyrosine-protein phosphatase non-receptor type substrate 1", "gene_name": "Sirpa", "organism": "Hamster", "refseq_name": "tyrosine-protein phosphatase non-receptor type substrate 1 isoform X4", "refseq_ac": [ { "id": "XP_027277625", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277625", "type": "external" } ], "gene_names_uniprotkb": "Sirpa", "gene_names_refseq": "Sirpa", "protein_names_uniprotkb": "Tyrosine-protein phosphatase non-receptor type substrate 1; Brain Ig-like molecule with tyrosine-based activation motifs; CD172 antigen-like family member A; Inhibitory receptor SHPS-1; Signal-regulatory protein alpha-1", "protein_names_refseq": "tyrosine-protein phosphatase non-receptor type substrate 1 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100751480)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017124 SH3 domain binding;GO:0019903 protein phosphatase binding", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0032675 regulation of interleukin-6 production;GO:0050765 negative regulation of phagocytosis;GO:0032680 regulation of tumor necrosis factor production;GO:0045428 regulation of nitric oxide biosynthetic process;GO:0097529 myeloid leukocyte migration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GA42-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GBC6-1", "uniprot_id": [ { "id": "A0A9J7GBC6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GBC6", "type": "external" } ], "mass": 192697.0, "length": 1727, "protein_name": "Gag-Pol polyprotein", "gene_name": "LOC103160953", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: uncharacterized protein LOC103160953 isoform X3", "refseq_ac": [ { "id": "XP_027278522", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278522", "type": "external" } ], "gene_names_uniprotkb": "LOC103160953", "gene_names_refseq": "LOC103160953", "protein_names_uniprotkb": "Gag-Pol polyprotein; 2.7.7.49; 3.1.26.4", "protein_names_refseq": "LOW QUALITY PROTEIN: uncharacterized protein LOC103160953 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:103160953)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases frameshifts :: corrected 8 indels internal stop codons :: corrected 3 genomic stop codons ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes viral DNA integration into the host chromosome, by performing a series of DNA cutting and joining reactions. This enzyme activity takes place after virion entry into a cell and reverse transcription of the RNA genome in dsDNA. The first step in the integration process is 3' processing. This step requires a complex comprising the viral genome, matrix protein and integrase. This complex is called the pre-integration complex (PIC). The integrase protein removes 2 nucleotides from each 3' end of the viral DNA, leaving recessed CA OH's at the 3' ends. In the second step that requires cell division, the PIC enters cell nucleus. In the third step, termed strand transfer, the integrase protein joins the previously processed 3' ends to the 5' ends of strands of target cellular DNA at the site of integration. The last step is viral DNA integration into host chromosome., [UniProtKB, UniProtKB]; Forms the spherical core of the virion that encapsulates the genomic RNA-nucleocapsid complex., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003676 nucleic acid binding;GO:0004190 aspartic-type endopeptidase activity;GO:0003964 RNA-directed DNA polymerase activity;GO:0003677 DNA binding", "go_cellular_component": "", "go_biological_process": "GO:0006508 proteolysis;GO:0019068 virion assembly;GO:0006310 DNA recombination;GO:0015074 DNA integration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GBC6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FZT8-1", "uniprot_id": [ { "id": "A0A9J7FZT8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FZT8", "type": "external" } ], "mass": 83335.0, "length": 730, "protein_name": "2'-5' oligoadenylate synthase", "gene_name": "Oas2", "organism": "Hamster", "refseq_name": "2'-5'-oligoadenylate synthase 2 isoform X3", "refseq_ac": [ { "id": "XP_027269934", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269934", "type": "external" } ], "gene_names_uniprotkb": "Oas2", "gene_names_refseq": "Oas2", "protein_names_uniprotkb": "2'-5' oligoadenylate synthase; 2.7.7.84", "protein_names_refseq": "2'-5'-oligoadenylate synthase 2 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:113831143)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.84", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.84", "type": "external" } ], "go_molecular_function": "GO:0003725 double-stranded RNA binding;GO:0001730 2'-5'-oligoadenylate synthetase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0045087 innate immune response;GO:0051607 defense response to virus;GO:0045071 negative regulation of viral genome replication", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FZT8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FXN9-1", "uniprot_id": [ { "id": "A0A9J7FXN9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FXN9", "type": "external" } ], "mass": 66323.0, "length": 594, "protein_name": "Tyrosine-protein kinase RYK", "gene_name": "Ryk", "organism": "Hamster", "refseq_name": "tyrosine-protein kinase RYK isoform X5", "refseq_ac": [ { "id": "XP_027270127", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270127", "type": "external" } ], "gene_names_uniprotkb": "Ryk", "gene_names_refseq": "Ryk", "protein_names_uniprotkb": "Tyrosine-protein kinase RYK; 2.7.10.1", "protein_names_refseq": "tyrosine-protein kinase RYK isoform X5", "tax_id": 10029, "disease": "", "pathway": " (cge:100771288)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0007409 axonogenesis;GO:0010976 positive regulation of neuron projection development;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0060071 Wnt signaling pathway, planar cell polarity pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FXN9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G0H5-1", "uniprot_id": [ { "id": "A0A9J7G0H5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G0H5", "type": "external" } ], "mass": 77670.0, "length": 676, "protein_name": "Beta-glucuronidase", "gene_name": "Gusb", "organism": "Hamster", "refseq_name": "beta-glucuronidase isoform X1", "refseq_ac": [ { "id": "XP_027240610", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240610", "type": "external" } ], "gene_names_uniprotkb": "Gusb", "gene_names_refseq": "Gusb", "protein_names_uniprotkb": "Beta-glucuronidase; 3.2.1.31", "protein_names_refseq": "beta-glucuronidase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100757362)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615685.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays an important role in the degradation of dermatan and keratan sulfates., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.2.1.31", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.31", "type": "external" } ], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0030246 carbohydrate binding;GO:0004566 beta-glucuronidase activity;GO:0019904 protein domain specific binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005764 lysosome;GO:0005783 endoplasmic reticulum;GO:0043202 lysosomal lumen", "go_biological_process": "GO:0019391 glucuronoside catabolic process;GO:0005975 carbohydrate metabolic process;GO:0030207 chondroitin sulfate proteoglycan catabolic process;GO:0030200 heparan sulfate proteoglycan catabolic process;GO:0030214 hyaluronan catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G0H5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FZH7-1", "uniprot_id": [ { "id": "A0A9J7FZH7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FZH7", "type": "external" } ], "mass": 24956.0, "length": 225, "protein_name": "Dual specificity mitogen-activated protein kinase kinase 1", "gene_name": "LOC113835540", "organism": "Hamster", "refseq_name": "dual specificity mitogen-activated protein kinase kinase 1-like isoform X1", "refseq_ac": [ { "id": "XP_027270576", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270576", "type": "external" } ], "gene_names_uniprotkb": "LOC113835540; LOC113830748; Snapc5", "gene_names_refseq": "LOC113835540", "protein_names_uniprotkb": "Dual specificity mitogen-activated protein kinase kinase 1; 2.7.12.2; ERK activator kinase 1; MAPK/ERK kinase 1", "protein_names_refseq": "dual specificity mitogen-activated protein kinase kinase 1-like isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:113835540)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0004708 MAP kinase kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005813 centrosome;GO:0031982 vesicle;GO:0070161 anchoring junction", "go_biological_process": "GO:0006366 transcription by RNA polymerase II;GO:0006384 transcription initiation at RNA polymerase III promoter", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FZH7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FZL2-1", "uniprot_id": [ { "id": "A0A9J7FZL2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FZL2", "type": "external" } ], "mass": 298815.0, "length": 2604, "protein_name": "Unconventional myosin-IXa", "gene_name": "Myo9a", "organism": "Hamster", "refseq_name": "unconventional myosin-IXa isoform X1", "refseq_ac": [ { "id": "XP_027270656", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270656", "type": "external" } ], "gene_names_uniprotkb": "Myo9a", "gene_names_refseq": "Myo9a", "protein_names_uniprotkb": "Unconventional myosin-IXa; Unconventional myosin-9a", "protein_names_refseq": "unconventional myosin-IXa isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100752004)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Regulates Rho by stimulating its GTPase activity in neurons. Required for the regulation of neurite branching and motor neuron axon guidance., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0051015 actin filament binding;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005884 actin filament;GO:0016020 membrane;GO:0045202 synapse;GO:0016459 myosin complex", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0045198 establishment of epithelial cell apical/basal polarity;GO:0034330 cell junction organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FZL2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FXL1-1", "uniprot_id": [ { "id": "A0A9J7FXL1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FXL1", "type": "external" } ], "mass": 68934.0, "length": 611, "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "Birc2", "organism": "Hamster", "refseq_name": "baculoviral IAP repeat-containing protein 2 isoform X1", "refseq_ac": [ { "id": "XP_003496184", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496184", "type": "external" } ], "gene_names_uniprotkb": "Birc2", "gene_names_refseq": "Birc2", "protein_names_uniprotkb": "RING-type E3 ubiquitin transferase; 2.3.2.27", "protein_names_refseq": "baculoviral IAP repeat-containing protein 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100756596)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613612.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003496184.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0006915 apoptotic process;GO:0043123 positive regulation of canonical NF-kappaB signal transduction;GO:2000377 regulation of reactive oxygen species metabolic process;GO:0033209 tumor necrosis factor-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FXL1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FXQ5-1", "uniprot_id": [ { "id": "A0A9J7FXQ5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FXQ5", "type": "external" } ], "mass": 48191.0, "length": 412, "protein_name": "tRNA methyltransferase 10 homolog C", "gene_name": "Trmt10c", "organism": "Hamster", "refseq_name": "tRNA methyltransferase 10 homolog C", "refseq_ac": [ { "id": "XP_027268303", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268303", "type": "external" } ], "gene_names_uniprotkb": "Trmt10c", "gene_names_refseq": "Trmt10c", "protein_names_uniprotkb": "tRNA methyltransferase 10 homolog C; 2.1.1.218; 2.1.1.221; Mitochondrial ribonuclease P protein 1; RNA (guanine-9-)-methyltransferase domain-containing protein 1; mRNA methyladenosine-N(1)-methyltransferase; tRNA (adenine(9)-N(1))-methyltransferase; tRNA (guanine(9)-N(1))-methyltransferase", "protein_names_refseq": "tRNA methyltransferase 10 homolog C", "tax_id": 10029, "disease": "", "pathway": " (cge:100756944)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.221", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.221", "type": "external" }, { "id": "2.1.1.218", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.218", "type": "external" }, { "id": "2.1.1.220", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.220", "type": "external" } ], "go_molecular_function": "GO:0000049 tRNA binding;GO:0052905 tRNA (guanosine(9)-N1)-methyltransferase activity;GO:0160106 tRNA (adenine(9)-N1)-methyltransferase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0042645 mitochondrial nucleoid", "go_biological_process": "GO:0032259 methylation;GO:0070131 positive regulation of mitochondrial translation;GO:0097745 mitochondrial tRNA 5'-end processing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FXQ5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FXQ8-1", "uniprot_id": [ { "id": "A0A9J7FXQ8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FXQ8", "type": "external" } ], "mass": 96658.0, "length": 872, "protein_name": "Programmed cell death 6-interacting protein", "gene_name": "Pdcd6ip", "organism": "Hamster", "refseq_name": "programmed cell death 6-interacting protein isoform X1", "refseq_ac": [ { "id": "XP_027271071", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271071", "type": "external" } ], "gene_names_uniprotkb": "Pdcd6ip", "gene_names_refseq": "Pdcd6ip", "protein_names_uniprotkb": "Programmed cell death 6-interacting protein; ALG-2-interacting protein 1", "protein_names_refseq": "programmed cell death 6-interacting protein isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100769458)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005768 endosome;GO:0005813 centrosome;GO:0005829 cytosol;GO:0005923 bicellular tight junction", "go_biological_process": "GO:0015031 protein transport;GO:0006915 apoptotic process;GO:0000281 mitotic cytokinesis;GO:0090559 regulation of membrane permeability;GO:0016236 macroautophagy", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FXQ8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FXW0-1", "uniprot_id": [ { "id": "A0A9J7FXW0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FXW0", "type": "external" } ], "mass": 49706.0, "length": 437, "protein_name": "Proline-serine-threonine phosphatase-interacting protein 1", "gene_name": "Pstpip1", "organism": "Hamster", "refseq_name": "proline-serine-threonine phosphatase-interacting protein 1 isoform X1", "refseq_ac": [ { "id": "XP_016823732", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016823732", "type": "external" } ], "gene_names_uniprotkb": "Pstpip1", "gene_names_refseq": "Pstpip1", "protein_names_uniprotkb": "Proline-serine-threonine phosphatase-interacting protein 1", "protein_names_refseq": "proline-serine-threonine phosphatase-interacting protein 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100765031)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613669.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in regulation of the actin cytoskeleton. May regulate WAS actin-bundling activity. Bridges the interaction between ABL1 and PTPN18 leading to ABL1 dephosphorylation. May play a role as a scaffold protein between PTPN12 and WAS and allow PTPN12 to dephosphorylate WAS. Has the potential to physically couple CD2 and CD2AP to WAS. Acts downstream of CD2 and CD2AP to recruit WAS to the T-cell:APC contact site so as to promote the actin polymerization required for synapse induction during T-cell activation. Down-regulates CD2-stimulated adhesion through the coupling of PTPN12 to CD2. Also has a role in innate immunity and the inflammatory response. Recruited to inflammasomes by MEFV. Induces formation of pyroptosomes, large supramolecular structures composed of oligomerized PYCARD dimers which form prior to inflammatory apoptosis. Binding to MEFV allows MEFV to bind to PYCARD and facilitates pyroptosome formation. Regulates endocytosis and cell migration in neutrophils., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding", "go_cellular_component": "GO:0005884 actin filament;GO:0030027 lamellipodium;GO:0048471 perinuclear region of cytoplasm;GO:0032154 cleavage furrow;GO:0001931 uropod", "go_biological_process": "GO:0006897 endocytosis;GO:0006954 inflammatory response;GO:0007155 cell adhesion;GO:0045087 innate immune response;GO:0030041 actin filament polymerization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FXW0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FXW6-1", "uniprot_id": [ { "id": "A0A9J7FXW6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FXW6", "type": "external" } ], "mass": 41331.0, "length": 370, "protein_name": "Nuclease EXOG, mitochondrial", "gene_name": "Exog", "organism": "Hamster", "refseq_name": "nuclease EXOG, mitochondrial", "refseq_ac": [ { "id": "XP_027271181", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271181", "type": "external" } ], "gene_names_uniprotkb": "Exog", "gene_names_refseq": "Exog", "protein_names_uniprotkb": "Nuclease EXOG, mitochondrial; Endonuclease G-like 1", "protein_names_refseq": "nuclease EXOG, mitochondrial", "tax_id": 10029, "disease": "", "pathway": " (cge:100750872)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single-stranded DNA and 5'-3' exonuclease activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0003676 nucleic acid binding;GO:0004521 RNA endonuclease activity;GO:0000014 single-stranded DNA endodeoxyribonuclease activity;GO:0008409 5'-3' exonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006309 apoptotic DNA fragmentation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FXW6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FXX1-1", "uniprot_id": [ { "id": "A0A9J7FXX1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FXX1", "type": "external" } ], "mass": 43133.0, "length": 375, "protein_name": "Neuronal acetylcholine receptor subunit alpha-5", "gene_name": "Chrna5", "organism": "Hamster", "refseq_name": "neuronal acetylcholine receptor subunit alpha-5", "refseq_ac": [ { "id": "XP_027270849", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270849", "type": "external" } ], "gene_names_uniprotkb": "Chrna5", "gene_names_refseq": "Chrna5", "protein_names_uniprotkb": "Neuronal acetylcholine receptor subunit alpha-5", "protein_names_refseq": "neuronal acetylcholine receptor subunit alpha-5", "tax_id": 10029, "disease": "", "pathway": " (cge:100762991)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of neuronal acetylcholine receptors (nAChRs) that function as pentameric, ligand-gated cation channels with high calcium permeability among other activities. nAChRs are excitatory neurotrasnmitter receptors formed by a collection of nAChR subunits known to mediate synaptic transmission in the nervous system and the neuromuscular junction. Each nAchR subunit confers differential attributes to channel properties, including activation, deactivation and desensitization kinetics, pH sensitivity, cation permeability, and binding to allosteric modulators. Has an accessory rather than functional role and is only able to form functional nAChRs when co-assembled with another beta subunit. Participates in pentameric assemblies along with CHRNA3, CHRNA4, CHRNB2 and CHRNB4. Increases receptor sensitivity to acetylcholine and nicotine when associated with CHRNA4 and CHRNB2. Plays a role in nicotine addiction., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity", "go_cellular_component": "GO:0005892 acetylcholine-gated channel complex;GO:0045211 postsynaptic membrane", "go_biological_process": "GO:0035094 response to nicotine", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FXX1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G0W7-1", "uniprot_id": [ { "id": "A0A9J7G0W7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G0W7", "type": "external" } ], "mass": 347500.0, "length": 3172, "protein_name": "E1A-binding protein p400", "gene_name": "Ep400", "organism": "Hamster", "refseq_name": "E1A-binding protein p400 isoform X9", "refseq_ac": [ { "id": "XP_027271685", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271685", "type": "external" } ], "gene_names_uniprotkb": "Ep400", "gene_names_refseq": "Ep400", "protein_names_uniprotkb": "E1A-binding protein p400; Domino homolog; p400 kDa SWI2/SNF2-related protein", "protein_names_refseq": "E1A-binding protein p400 isoform X9", "tax_id": 10029, "disease": "", "pathway": " (cge:100770341)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 6, "predicted_n_glycosites": 0, "predicted_o_glycosites": 6, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0004386 helicase activity", "go_cellular_component": "GO:0035267 NuA4 histone acetyltransferase complex;GO:0000812 Swr1 complex", "go_biological_process": "GO:0006281 DNA repair;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G0W7-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FY25-1", "uniprot_id": [ { "id": "A0A9J7FY25_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FY25", "type": "external" } ], "mass": 149883.0, "length": 1415, "protein_name": "Protein HEG homolog 1", "gene_name": "Heg1", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: protein HEG homolog 1 isoform X5", "refseq_ac": [ { "id": "XP_027268598", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268598", "type": "external" } ], "gene_names_uniprotkb": "Heg1", "gene_names_refseq": "Heg1", "protein_names_uniprotkb": "Protein HEG homolog 1", "protein_names_refseq": "LOW QUALITY PROTEIN: protein HEG homolog 1 isoform X5", "tax_id": 10029, "disease": "", "pathway": " (cge:100764801)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005911 cell-cell junction", "go_biological_process": "GO:0007507 heart development;GO:0060255 regulation of macromolecule metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FY25-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FY38-1", "uniprot_id": [ { "id": "A0A9J7FY38_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FY38", "type": "external" } ], "mass": 58200.0, "length": 512, "protein_name": "Matrix metalloproteinase-27 isoform X2", "gene_name": "Mmp27", "organism": "Hamster", "refseq_name": "matrix metalloproteinase-27 isoform X2", "refseq_ac": [ { "id": "XP_027270978", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270978", "type": "external" } ], "gene_names_uniprotkb": "Mmp27", "gene_names_refseq": "Mmp27", "protein_names_uniprotkb": "Matrix metalloproteinase-27 isoform X2", "protein_names_refseq": "matrix metalloproteinase-27 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100755427)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0031012 extracellular matrix", "go_biological_process": "GO:0006508 proteolysis;GO:0030198 extracellular matrix organization;GO:0030574 collagen catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FY38-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FY65-1", "uniprot_id": [ { "id": "A0A9J7FY65_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FY65", "type": "external" } ], "mass": 67741.0, "length": 598, "protein_name": "Polypeptide N-acetylgalactosaminyltransferase", "gene_name": "Galnt17", "organism": "Hamster", "refseq_name": "polypeptide N-acetylgalactosaminyltransferase 17 isoform X2", "refseq_ac": [ { "id": "XP_027271900", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271900", "type": "external" } ], "gene_names_uniprotkb": "Galnt17", "gene_names_refseq": "Galnt17", "protein_names_uniprotkb": "Polypeptide N-acetylgalactosaminyltransferase; 2.4.1.-; Protein-UDP acetylgalactosaminyltransferase", "protein_names_refseq": "polypeptide N-acetylgalactosaminyltransferase 17 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100750837)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.-", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0030246 carbohydrate binding;GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0006493 protein O-linked glycosylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FY65-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FYG0-1", "uniprot_id": [ { "id": "A0A9J7FYG0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FYG0", "type": "external" } ], "mass": 101967.0, "length": 929, "protein_name": "A disintegrin and metalloproteinase with thrombospondin motifs 5", "gene_name": "Adamts5", "organism": "Hamster", "refseq_name": "A disintegrin and metalloproteinase with thrombospondin motifs 5", "refseq_ac": [ { "id": "XP_027268159", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268159", "type": "external" } ], "gene_names_uniprotkb": "Adamts5", "gene_names_refseq": "Adamts5", "protein_names_uniprotkb": "A disintegrin and metalloproteinase with thrombospondin motifs 5; ADMP-2; Aggrecanase-2", "protein_names_refseq": "A disintegrin and metalloproteinase with thrombospondin motifs 5", "tax_id": 10029, "disease": "", "pathway": " (cge:100761876)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0031012 extracellular matrix", "go_biological_process": "GO:0006508 proteolysis;GO:0030198 extracellular matrix organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FYG0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FYL9-1", "uniprot_id": [ { "id": "A0A9J7FYL9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FYL9", "type": "external" } ], "mass": 140570.0, "length": 1221, "protein_name": "Solute carrier family 9 member C1", "gene_name": "Slc9c1", "organism": "Hamster", "refseq_name": "sodium/hydrogen exchanger 10", "refseq_ac": [ { "id": "XP_003497920", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497920", "type": "external" } ], "gene_names_uniprotkb": "Slc9c1", "gene_names_refseq": "Slc9c1", "protein_names_uniprotkb": "Solute carrier family 9 member C1; Na(+)/H(+) exchanger 10; Sodium/hydrogen exchanger 10; Sperm-specific Na(+)/H(+) exchanger", "protein_names_refseq": "sodium/hydrogen exchanger 10", "tax_id": 10029, "disease": "", "pathway": " (cge:100771267)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 5% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613667.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Sperm-specific solute carrier involved in intracellular pH regulation of spermatozoa. Required for sperm motility and fertility. Involved in sperm cell hyperactivation, a step needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for the expression and bicarbonate regulation of the soluble adenylyl cyclase (sAC)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015385 sodium:proton antiporter activity;GO:0015386 potassium:proton antiporter activity;GO:0005216 monoatomic ion channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0031514 motile cilium", "go_biological_process": "GO:0051453 regulation of intracellular pH;GO:0098719 sodium ion import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FYL9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G0N3-1", "uniprot_id": [ { "id": "A0A9J7G0N3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G0N3", "type": "external" } ], "mass": 94948.0, "length": 864, "protein_name": "Biotin--protein ligase", "gene_name": "Hlcs", "organism": "Hamster", "refseq_name": "biotin--protein ligase isoform X2", "refseq_ac": [ { "id": "XP_027271446", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271446", "type": "external" } ], "gene_names_uniprotkb": "Hlcs", "gene_names_refseq": "Hlcs", "protein_names_uniprotkb": "Biotin--protein ligase; 6.3.4.10; 6.3.4.11; 6.3.4.15; 6.3.4.9; Biotin apo-protein ligase", "protein_names_refseq": "biotin--protein ligase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100752840)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Biotin--protein ligase catalyzing the biotinylation of the 4 biotin-dependent carboxylases acetyl-CoA-carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, and methylcrotonyl-CoA carboxylase., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.3.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.4.10", "type": "external" }, { "id": "6.3.4.11", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.4.11", "type": "external" }, { "id": "6.3.4.15", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.4.15", "type": "external" }, { "id": "6.3.4.9", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.4.9", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004077 biotin--[biotin carboxyl-carrier protein] ligase activity;GO:0019899 enzyme binding;GO:0009374 biotin binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016363 nuclear matrix;GO:0000785 chromatin", "go_biological_process": "GO:0006768 biotin metabolic process;GO:0043687 post-translational protein modification;GO:0070781 response to biotin", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G0N3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FYR7-1", "uniprot_id": [ { "id": "A0A9J7FYR7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FYR7", "type": "external" } ], "mass": 81925.0, "length": 723, "protein_name": "S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1", "gene_name": "LOC100751910", "organism": "Hamster", "refseq_name": "S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1 isoform X2", "refseq_ac": [ { "id": "XP_027271897", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271897", "type": "external" } ], "gene_names_uniprotkb": "LOC100751910", "gene_names_refseq": "LOC100751910", "protein_names_uniprotkb": "S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1; 4.1.3.44; Radical S-adenosyl methionine and flavodoxin domain-containing protein 1; tRNA wybutosine-synthesizing protein 1 homolog; tRNA-yW-synthesizing protein", "protein_names_refseq": "S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100751910)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.1.3.44", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.3.44", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0010181 FMN binding;GO:0102521 tRNA-4-demethylwyosine synthase activity", "go_cellular_component": "", "go_biological_process": "GO:0031591 wybutosine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FYR7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FYW3-1", "uniprot_id": [ { "id": "A0A9J7FYW3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FYW3", "type": "external" } ], "mass": 43872.0, "length": 424, "protein_name": "LOW QUALITY PROTEIN: 3-ketoacyl-CoA thiolase B, peroxisomal isoform X2", "gene_name": "LOC100753943", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: 3-ketoacyl-CoA thiolase B, peroxisomal isoform X2", "refseq_ac": [ { "id": "XP_027271164", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271164", "type": "external" } ], "gene_names_uniprotkb": "LOC100753943", "gene_names_refseq": "LOC100753943", "protein_names_uniprotkb": "LOW QUALITY PROTEIN: 3-ketoacyl-CoA thiolase B, peroxisomal isoform X2", "protein_names_refseq": "LOW QUALITY PROTEIN: 3-ketoacyl-CoA thiolase B, peroxisomal isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100753943)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.16", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.16", "type": "external" }, { "id": "2.3.1.155", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.155", "type": "external" }, { "id": "2.3.1.176", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.176", "type": "external" } ], "go_molecular_function": "GO:0003985 acetyl-CoA C-acetyltransferase activity;GO:0050633 acetyl-CoA C-myristoyltransferase activity", "go_cellular_component": "GO:0005777 peroxisome", "go_biological_process": "GO:0010124 phenylacetate catabolic process;GO:0006635 fatty acid beta-oxidation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FYW3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FYY3-1", "uniprot_id": [ { "id": "A0A9J7FYY3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FYY3", "type": "external" } ], "mass": 152833.0, "length": 1358, "protein_name": "Phosphoinositide 3-kinase regulatory subunit 4", "gene_name": "Pik3r4", "organism": "Hamster", "refseq_name": "phosphoinositide 3-kinase regulatory subunit 4 isoform X2", "refseq_ac": [ { "id": "XP_027270169", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270169", "type": "external" } ], "gene_names_uniprotkb": "Pik3r4", "gene_names_refseq": "Pik3r4", "protein_names_uniprotkb": "Phosphoinositide 3-kinase regulatory subunit 4; 2.7.11.1", "protein_names_refseq": "phosphoinositide 3-kinase regulatory subunit 4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100769548)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Regulatory subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0071561 nucleus-vacuole junction;GO:0005856 cytoskeleton;GO:0005929 cilium;GO:0005770 late endosome;GO:0005776 autophagosome", "go_biological_process": "GO:0016236 macroautophagy;GO:0045324 late endosome to vacuole transport;GO:0006623 protein targeting to vacuole", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FYY3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FZ19-1", "uniprot_id": [ { "id": "A0A9J7FZ19_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FZ19", "type": "external" } ], "mass": 139230.0, "length": 1263, "protein_name": "Adenylate cyclase type 5", "gene_name": "Adcy5", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: adenylate cyclase type 5 isoform X2", "refseq_ac": [ { "id": "XP_027268575", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268575", "type": "external" } ], "gene_names_uniprotkb": "Adcy5", "gene_names_refseq": "Adcy5", "protein_names_uniprotkb": "Adenylate cyclase type 5; 4.6.1.1; ATP pyrophosphate-lyase 5; Adenylate cyclase type V; Adenylyl cyclase 5", "protein_names_refseq": "LOW QUALITY PROTEIN: adenylate cyclase type 5 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100765958)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates signaling downstream of ADRB1. Regulates the increase of free cytosolic Ca(2+) in response to increased blood glucose levels and contributes to the regulation of Ca(2+)-dependent insulin secretion., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:4.6.1.1", "type": "external" } ], "go_molecular_function": "GO:0004016 adenylate cyclase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005929 cilium", "go_biological_process": "GO:0006171 cAMP biosynthetic process;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FZ19-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FZ53-1", "uniprot_id": [ { "id": "A0A9J7FZ53_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FZ53", "type": "external" } ], "mass": 126310.0, "length": 1132, "protein_name": "Lysine-specific demethylase 4B", "gene_name": "Kdm4b", "organism": "Hamster", "refseq_name": "lysine-specific demethylase 4B isoform X2", "refseq_ac": [ { "id": "XP_027272652", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272652", "type": "external" } ], "gene_names_uniprotkb": "Kdm4b", "gene_names_refseq": "Kdm4b", "protein_names_uniprotkb": "Lysine-specific demethylase 4B; 1.14.11.66; JmjC domain-containing histone demethylation protein 3B; Jumonji domain-containing protein 2B; [histone H3]-trimethyl-L-lysine(9) demethylase 4B", "protein_names_refseq": "lysine-specific demethylase 4B isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100770247)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate. Plays a critical role in the development of the central nervous system (CNS)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.66", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.66", "type": "external" }, { "id": "1.14.11.69", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.69", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0140684 histone H3K9me2/H3K9me3 demethylase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005721 pericentric heterochromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FZ53-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FZA5-1", "uniprot_id": [ { "id": "A0A9J7FZA5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FZA5", "type": "external" } ], "mass": 189223.0, "length": 1702, "protein_name": "Gag-Pol polyprotein", "gene_name": "LOC113835851", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: uncharacterized protein LOC113835851", "refseq_ac": [ { "id": "XP_027272754", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272754", "type": "external" } ], "gene_names_uniprotkb": "LOC113835851", "gene_names_refseq": "LOC113835851", "protein_names_uniprotkb": "Gag-Pol polyprotein; 2.7.7.49; 3.1.26.4", "protein_names_refseq": "LOW QUALITY PROTEIN: uncharacterized protein LOC113835851", "tax_id": 10029, "disease": "", "pathway": " (cge:113835851)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes viral DNA integration into the host chromosome, by performing a series of DNA cutting and joining reactions. This enzyme activity takes place after virion entry into a cell and reverse transcription of the RNA genome in dsDNA. The first step in the integration process is 3' processing. This step requires a complex comprising the viral genome, matrix protein and integrase. This complex is called the pre-integration complex (PIC). The integrase protein removes 2 nucleotides from each 3' end of the viral DNA, leaving recessed CA OH's at the 3' ends. In the second step that requires cell division, the PIC enters cell nucleus. In the third step, termed strand transfer, the integrase protein joins the previously processed 3' ends to the 5' ends of strands of target cellular DNA at the site of integration. The last step is viral DNA integration into host chromosome., [UniProtKB, UniProtKB]; Forms the spherical core of the virion that encapsulates the genomic RNA-nucleocapsid complex., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003964 RNA-directed DNA polymerase activity;GO:0003677 DNA binding;GO:0003723 RNA binding;GO:0008270 zinc ion binding;GO:0004523 RNA-DNA hybrid ribonuclease activity", "go_cellular_component": "", "go_biological_process": "GO:0006310 DNA recombination;GO:0006508 proteolysis;GO:0019068 virion assembly;GO:0015074 DNA integration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FZA5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FZA7-1", "uniprot_id": [ { "id": "A0A9J7FZA7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FZA7", "type": "external" } ], "mass": 72445.0, "length": 645, "protein_name": "LIM domain kinase 1", "gene_name": "Limk1", "organism": "Hamster", "refseq_name": "LIM domain kinase 1 isoform X2", "refseq_ac": [ { "id": "XP_027271952", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271952", "type": "external" } ], "gene_names_uniprotkb": "Limk1", "gene_names_refseq": "Limk1", "protein_names_uniprotkb": "LIM domain kinase 1; 2.7.11.1", "protein_names_refseq": "LIM domain kinase 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100770918)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Serine/threonine-protein kinase that plays an essential role in the regulation of actin filament dynamics. Acts downstream of several Rho family GTPase signal transduction pathways. Activated by upstream kinases including ROCK1, PAK1 and PAK4, which phosphorylate LIMK1 on a threonine residue located in its activation loop. LIMK1 subsequently phosphorylates and inactivates the actin binding/depolymerizing factors cofilin-1/CFL1, cofilin-2/CFL2 and destrin/DSTN, thereby preventing the cleavage of filamentous actin (F-actin), and stabilizing the actin cytoskeleton. In this way LIMK1 regulates several actin-dependent biological processes including cell motility, cell cycle progression, and differentiation. Phosphorylates TPPP on serine residues, thereby promoting microtubule disassembly. Stimulates axonal outgrowth and may be involved in brain development., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0031072 heat shock protein binding;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0030054 cell junction;GO:0043005 neuron projection", "go_biological_process": "GO:0030036 actin cytoskeleton organization;GO:0051496 positive regulation of stress fiber assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FZA7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FZB0-1", "uniprot_id": [ { "id": "A0A9J7FZB0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FZB0", "type": "external" } ], "mass": 54478.0, "length": 493, "protein_name": "Cytochrome P450 2W1", "gene_name": "LOC100768731", "organism": "Hamster", "refseq_name": "cytochrome P450 2W1", "refseq_ac": [ { "id": "XP_027269569", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269569", "type": "external" } ], "gene_names_uniprotkb": "LOC100768731", "gene_names_refseq": "LOC100768731", "protein_names_uniprotkb": "Cytochrome P450 2W1", "protein_names_refseq": "cytochrome P450 2W1", "tax_id": 10029, "disease": "", "pathway": " (cge:100768731)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006805 xenobiotic metabolic process;GO:0006082 organic acid metabolic process;GO:0046222 aflatoxin metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FZB0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FZB5-1", "uniprot_id": [ { "id": "A0A9J7FZB5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FZB5", "type": "external" } ], "mass": 55579.0, "length": 500, "protein_name": "E3 ubiquitin-protein ligase Hakai", "gene_name": "Cbll1", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase Hakai isoform X1", "refseq_ac": [ { "id": "XP_007648127", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007648127", "type": "external" } ], "gene_names_uniprotkb": "Cbll1", "gene_names_refseq": "Cbll1", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase Hakai; 2.3.2.27; Casitas B-lineage lymphoma-transforming sequence-like protein 1; RING-type E3 ubiquitin transferase Hakai", "protein_names_refseq": "E3 ubiquitin-protein ligase Hakai isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100758211)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614696.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; E3 ubiquitin-protein ligase that mediates ubiquitination of several tyrosine-phosphorylated Src substrates, including CDH1, CTTN and DOK1. Targets CDH1 for endocytosis and degradation. Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing. Its function in the WMM complex is unknown., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0036396 RNA N6-methyladenosine methyltransferase complex;GO:0005737 cytoplasm;GO:0016607 nuclear speck", "go_biological_process": "GO:0030155 regulation of cell adhesion;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FZB5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FZG2-1", "uniprot_id": [ { "id": "A0A9J7FZG2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FZG2", "type": "external" } ], "mass": 108467.0, "length": 987, "protein_name": "Ephrin type-B receptor 4", "gene_name": "Ephb4", "organism": "Hamster", "refseq_name": "ephrin type-B receptor 4 isoform X2", "refseq_ac": [ { "id": "XP_027272025", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272025", "type": "external" } ], "gene_names_uniprotkb": "Ephb4", "gene_names_refseq": "Ephb4", "protein_names_uniprotkb": "Ephrin type-B receptor 4; 2.7.10.1; Hepatoma transmembrane kinase", "protein_names_refseq": "ephrin type-B receptor 4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100769535)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 it is involved in the regulation of cell adhesion and migration, and plays a central role in heart morphogenesis, angiogenesis and blood vessel remodeling and permeability. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0005005 transmembrane-ephrin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030425 dendrite", "go_biological_process": "GO:0001525 angiogenesis;GO:0007411 axon guidance;GO:0048513 animal organ development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FZG2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FZI0-1", "uniprot_id": [ { "id": "A0A9J7FZI0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FZI0", "type": "external" } ], "mass": 286885.0, "length": 2588, "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "Hectd1", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase HECTD1 isoform X5", "refseq_ac": [ { "id": "XP_027272089", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272089", "type": "external" } ], "gene_names_uniprotkb": "Hectd1", "gene_names_refseq": "Hectd1", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase; 2.3.2.26", "protein_names_refseq": "E3 ubiquitin-protein ligase HECTD1 isoform X5", "tax_id": 10029, "disease": "", "pathway": " (cge:100762999)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0016607 nuclear speck", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0070534 protein K63-linked ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FZI0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FZJ2-1", "uniprot_id": [ { "id": "A0A9J7FZJ2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FZJ2", "type": "external" } ], "mass": 45726.0, "length": 420, "protein_name": "Zona pellucida sperm-binding protein 3", "gene_name": "Zp3", "organism": "Hamster", "refseq_name": "zona pellucida sperm-binding protein 3 isoform X2", "refseq_ac": [ { "id": "XP_027272085", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272085", "type": "external" } ], "gene_names_uniprotkb": "Zp3", "gene_names_refseq": "Zp3", "protein_names_uniprotkb": "Zona pellucida sperm-binding protein 3", "protein_names_refseq": "zona pellucida sperm-binding protein 3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100764645)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0035804 structural constituent of egg coat;GO:0032190 acrosin binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0035805 egg coat", "go_biological_process": "GO:2000344 positive regulation of acrosome reaction;GO:0035803 egg coat formation;GO:0007339 binding of sperm to zona pellucida", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FZJ2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G2J9-1", "uniprot_id": [ { "id": "A0A9J7G2J9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G2J9", "type": "external" } ], "mass": 87251.0, "length": 797, "protein_name": "Striatin-3", "gene_name": "Strn3", "organism": "Hamster", "refseq_name": "striatin-3 isoform X6", "refseq_ac": [ { "id": "XP_027272098", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272098", "type": "external" } ], "gene_names_uniprotkb": "Strn3", "gene_names_refseq": "Strn3", "protein_names_uniprotkb": "Striatin-3; Cell cycle autoantigen SG2NA; S/G2 antigen", "protein_names_refseq": "striatin-3 isoform X6", "tax_id": 10029, "disease": "", "pathway": " (cge:100765220)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Calmodulin-binding scaffolding protein which is the center of the striatin-interacting phosphatase and kinase (STRIPAK) complexes. STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytoskeleton remodeling. Different types of STRIPAK complexes are involved in a variety of biological processes such as cell growth, differentiation, apoptosis, metabolism and immune regulation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0044877 protein-containing complex binding;GO:0051721 protein phosphatase 2A binding;GO:0070016 armadillo repeat domain binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0030425 dendrite", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G2J9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G1N4-1", "uniprot_id": [ { "id": "A0A9J7G1N4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G1N4", "type": "external" } ], "mass": 222304.0, "length": 1986, "protein_name": "RNA helicase", "gene_name": "Fancm", "organism": "Hamster", "refseq_name": "Fanconi anemia group M protein isoform X2", "refseq_ac": [ { "id": "XP_027272307", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272307", "type": "external" } ], "gene_names_uniprotkb": "Fancm", "gene_names_refseq": "Fancm", "protein_names_uniprotkb": "RNA helicase; 3.6.4.13; ATP-dependent RNA helicase FANCM", "protein_names_refseq": "Fanconi anemia group M protein isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100768967)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage. In complex with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork-structured DNA (fsDNA) and Holliday junction substrates. Its ATP-dependent DNA branch migration activity can process branched DNA structures such as a movable replication fork. This activity is strongly stimulated in the presence of CENPS and CENPX. In complex with FAAP24, efficiently binds to single-strand DNA (ssDNA), splayed-arm DNA, and 3'-flap substrates. In vitro, on its own, strongly binds ssDNA oligomers and weakly fsDNA, but does not bind to dsDNA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0043138 3'-5' DNA helicase activity;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0000400 four-way junction DNA binding;GO:0009378 four-way junction helicase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0036297 interstrand cross-link repair;GO:0045003 double-strand break repair via synthesis-dependent strand annealing;GO:0035825 homologous recombination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G1N4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FZN6-1", "uniprot_id": [ { "id": "A0A9J7FZN6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FZN6", "type": "external" } ], "mass": 118797.0, "length": 1071, "protein_name": "Protein transport protein sec16", "gene_name": "LOC100752724", "organism": "Hamster", "refseq_name": "protein transport protein Sec16B isoform X1", "refseq_ac": [ { "id": "XP_027273078", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273078", "type": "external" } ], "gene_names_uniprotkb": "LOC100752724", "gene_names_refseq": "LOC100752724", "protein_names_uniprotkb": "Protein transport protein sec16", "protein_names_refseq": "protein transport protein Sec16B isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100752724)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. Involved in peroxisome biogenesis. Regulates the transport of peroxisomal biogenesis factors PEX3 and PEX16 from the ER to peroxisomes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005789 endoplasmic reticulum membrane;GO:0012507 ER to Golgi transport vesicle membrane;GO:0070971 endoplasmic reticulum exit site", "go_biological_process": "GO:0015031 protein transport;GO:0007031 peroxisome organization;GO:0016192 vesicle-mediated transport;GO:0007030 Golgi organization;GO:0070973 protein localization to endoplasmic reticulum exit site", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FZN6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FZP9-1", "uniprot_id": [ { "id": "A0A9J7FZP9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FZP9", "type": "external" } ], "mass": 84890.0, "length": 767, "protein_name": "Integrin beta", "gene_name": "Itgb8", "organism": "Hamster", "refseq_name": "integrin beta-8", "refseq_ac": [ { "id": "XP_027272218", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272218", "type": "external" } ], "gene_names_uniprotkb": "Itgb8", "gene_names_refseq": "Itgb8", "protein_names_uniprotkb": "Integrin beta", "protein_names_refseq": "integrin beta-8", "tax_id": 10029, "disease": "", "pathway": " (cge:100769713)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation on the surface of activated regulatory T-cells (Tregs). Required during vasculogenesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005925 focal adhesion;GO:0009986 cell surface;GO:0034686 integrin alphav-beta8 complex", "go_biological_process": "GO:0007229 integrin-mediated signaling pathway;GO:0016477 cell migration;GO:0030154 cell differentiation;GO:0033627 cell adhesion mediated by integrin;GO:0098609 cell-cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FZP9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FZV6-1", "uniprot_id": [ { "id": "A0A9J7FZV6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FZV6", "type": "external" } ], "mass": 42756.0, "length": 381, "protein_name": "Creatine kinase B-type", "gene_name": "Ckb", "organism": "Hamster", "refseq_name": "creatine kinase B-type isoform X2", "refseq_ac": [ { "id": "XP_027272538", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272538", "type": "external" } ], "gene_names_uniprotkb": "Ckb", "gene_names_refseq": "Ckb", "protein_names_uniprotkb": "Creatine kinase B-type; 2.7.3.2; Creatine kinase B chain", "protein_names_refseq": "creatine kinase B-type isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774847)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Acts as a key regulator of adaptive thermogenesis as part of the futile creatine cycle: localizes to the mitochondria of thermogenic fat cells and acts by mediating phosphorylation of creatine to initiate a futile cycle of creatine phosphorylation and dephosphorylation. During the futile creatine cycle, creatine and N-phosphocreatine are in a futile cycle, which dissipates the high energy charge of N-phosphocreatine as heat without performing any mechanical or chemical work., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.3.2", "type": "external" } ], "go_molecular_function": "GO:0004111 creatine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0046314 phosphocreatine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FZV6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FZW1-1", "uniprot_id": [ { "id": "A0A9J7FZW1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FZW1", "type": "external" } ], "mass": 48043.0, "length": 418, "protein_name": "MAPK/MAK/MRK overlapping kinase", "gene_name": "Mok", "organism": "Hamster", "refseq_name": "MAPK/MAK/MRK overlapping kinase isoform X1", "refseq_ac": [ { "id": "XP_016827844", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016827844", "type": "external" } ], "gene_names_uniprotkb": "Mok", "gene_names_refseq": "Mok", "protein_names_uniprotkb": "MAPK/MAK/MRK overlapping kinase; 2.7.11.22; MOK protein kinase", "protein_names_refseq": "MAPK/MAK/MRK overlapping kinase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100772524)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 224 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613702.1) and transcript sequence (IACG01031507.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_016827844.1. COMPLETENESS: full length., [RefSeq]; Able to phosphorylate several exogenous substrates and to undergo autophosphorylation. Negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004693 cyclin-dependent protein serine/threonine kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0004672 protein kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005929 cilium", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FZW1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FZY1-1", "uniprot_id": [ { "id": "A0A9J7FZY1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FZY1", "type": "external" } ], "mass": 109107.0, "length": 974, "protein_name": "Kinesin-like protein", "gene_name": "LOC100769633", "organism": "Hamster", "refseq_name": "kinesin-like protein KIF19", "refseq_ac": [ { "id": "XP_027269199", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269199", "type": "external" } ], "gene_names_uniprotkb": "LOC100769633", "gene_names_refseq": "LOC100769633", "protein_names_uniprotkb": "Kinesin-like protein", "protein_names_refseq": "kinesin-like protein KIF19", "tax_id": 10029, "disease": "", "pathway": " (cge:100769633)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027269199.1. COMPLETENESS: full length., [RefSeq]; Plus end-directed microtubule-dependent motor protein that regulates the length of motile cilia by mediating depolymerization of microtubules at ciliary tips., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0003777 microtubule motor activity", "go_cellular_component": "GO:0005874 microtubule;GO:0005929 cilium", "go_biological_process": "GO:0007018 microtubule-based movement", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FZY1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G002-1", "uniprot_id": [ { "id": "A0A9J7G002_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G002", "type": "external" } ], "mass": 96533.0, "length": 865, "protein_name": "Extended synaptotagmin-2", "gene_name": "Esyt2", "organism": "Hamster", "refseq_name": "extended synaptotagmin-2 isoform X3", "refseq_ac": [ { "id": "XP_027272835", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272835", "type": "external" } ], "gene_names_uniprotkb": "Esyt2", "gene_names_refseq": "Esyt2", "protein_names_uniprotkb": "Extended synaptotagmin-2", "protein_names_refseq": "extended synaptotagmin-2 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100761977)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding; this occurs most likely via the AP-2 complex. Promotes the localization of SACM1L at endoplasmic reticulum-plasma membrane contact sites (EPCS)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0005544 calcium-dependent phospholipid binding;GO:0008429 phosphatidylethanolamine binding;GO:0031210 phosphatidylcholine binding;GO:0035091 phosphatidylinositol binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006869 lipid transport;GO:0006897 endocytosis;GO:0061817 endoplasmic reticulum-plasma membrane tethering", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G002-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G123-1", "uniprot_id": [ { "id": "A0A9J7G123_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G123", "type": "external" } ], "mass": 493039.0, "length": 4312, "protein_name": "Cytoplasmic dynein 2 heavy chain 1", "gene_name": "Dync2h1", "organism": "Hamster", "refseq_name": "cytoplasmic dynein 2 heavy chain 1 isoform X2", "refseq_ac": [ { "id": "XP_027270974", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270974", "type": "external" } ], "gene_names_uniprotkb": "Dync2h1", "gene_names_refseq": "Dync2h1", "protein_names_uniprotkb": "Cytoplasmic dynein 2 heavy chain 1; Cytoplasmic dynein 2 heavy chain; Dynein cytoplasmic heavy chain 2; Dynein heavy chain isotype 1B", "protein_names_refseq": "cytoplasmic dynein 2 heavy chain 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100758806)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008569 minus-end-directed microtubule motor activity;GO:0051959 dynein light intermediate chain binding;GO:0045505 dynein intermediate chain binding", "go_cellular_component": "GO:0005874 microtubule;GO:0005886 plasma membrane;GO:0005930 axoneme;GO:0030286 dynein complex;GO:0005858 axonemal dynein complex", "go_biological_process": "GO:0060271 cilium assembly;GO:0007018 microtubule-based movement", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G123-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G1F6-1", "uniprot_id": [ { "id": "A0A9J7G1F6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G1F6", "type": "external" } ], "mass": 120809.0, "length": 1071, "protein_name": "SLIT-ROBO Rho GTPase-activating protein 2", "gene_name": "Srgap2", "organism": "Hamster", "refseq_name": "SLIT-ROBO Rho GTPase-activating protein 2 isoform X1", "refseq_ac": [ { "id": "XP_027273469", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273469", "type": "external" } ], "gene_names_uniprotkb": "Srgap2", "gene_names_refseq": "Srgap2", "protein_names_uniprotkb": "SLIT-ROBO Rho GTPase-activating protein 2", "protein_names_refseq": "SLIT-ROBO Rho GTPase-activating protein 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100758268)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0014069 postsynaptic density;GO:0030027 lamellipodium;GO:0043197 dendritic spine", "go_biological_process": "GO:0007165 signal transduction;GO:0007399 nervous system development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G1F6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G0A4-1", "uniprot_id": [ { "id": "A0A9J7G0A4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G0A4", "type": "external" } ], "mass": 43938.0, "length": 424, "protein_name": "LOW QUALITY PROTEIN: 3-ketoacyl-CoA thiolase B, peroxisomal isoform X2", "gene_name": "LOC100754813", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: 3-ketoacyl-CoA thiolase B, peroxisomal isoform X2", "refseq_ac": [ { "id": "XP_027271169", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271169", "type": "external" } ], "gene_names_uniprotkb": "LOC100754813", "gene_names_refseq": "LOC100754813", "protein_names_uniprotkb": "LOW QUALITY PROTEIN: 3-ketoacyl-CoA thiolase B, peroxisomal isoform X2", "protein_names_refseq": "LOW QUALITY PROTEIN: 3-ketoacyl-CoA thiolase B, peroxisomal isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754813)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.16", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.16", "type": "external" }, { "id": "2.3.1.155", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.155", "type": "external" }, { "id": "2.3.1.176", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.176", "type": "external" } ], "go_molecular_function": "GO:0003985 acetyl-CoA C-acetyltransferase activity;GO:0050633 acetyl-CoA C-myristoyltransferase activity", "go_cellular_component": "GO:0005777 peroxisome", "go_biological_process": "GO:0010124 phenylacetate catabolic process;GO:0006635 fatty acid beta-oxidation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G0A4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G2E2-1", "uniprot_id": [ { "id": "A0A9J7G2E2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G2E2", "type": "external" } ], "mass": 63403.0, "length": 567, "protein_name": "UDP-N-acetylhexosamine pyrophosphorylase", "gene_name": "Uap1", "organism": "Hamster", "refseq_name": "UDP-N-acetylhexosamine pyrophosphorylase isoform X1", "refseq_ac": [ { "id": "XP_016832797", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016832797", "type": "external" } ], "gene_names_uniprotkb": "Uap1", "gene_names_refseq": "Uap1", "protein_names_uniprotkb": "UDP-N-acetylhexosamine pyrophosphorylase; 2.7.7.23; 2.7.7.83; Protein-pyrophosphorylation enzyme; UDP-N-acetylgalactosamine pyrophosphorylase; UDP-N-acetylglucosamine pyrophosphorylase", "protein_names_refseq": "UDP-N-acetylhexosamine pyrophosphorylase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100768154)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 241 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614194.1) and transcript sequence (IACG01078753.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_016832797.1. COMPLETENESS: full length., [RefSeq]; Isoform AGX1 has 2 to 3 times higher activity towards galactosamine 1-phosphate (GalNAc-1-P)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Isoform AGX2 has 8 times more activity towards glucosamine 1-phosphate (GlcNAc-1-P)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.23", "type": "external" }, { "id": "2.7.7.83", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.83", "type": "external" } ], "go_molecular_function": "GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity;GO:0052630 UDP-N-acetylgalactosamine diphosphorylase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0045087 innate immune response;GO:0006048 UDP-N-acetylglucosamine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G2E2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G0I3-1", "uniprot_id": [ { "id": "A0A9J7G0I3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G0I3", "type": "external" } ], "mass": 272536.0, "length": 2417, "protein_name": "Nucleoprotein TPR", "gene_name": "Tpr", "organism": "Hamster", "refseq_name": "nucleoprotein TPR isoform X2", "refseq_ac": [ { "id": "XP_027273207", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273207", "type": "external" } ], "gene_names_uniprotkb": "Tpr", "gene_names_refseq": "Tpr", "protein_names_uniprotkb": "Nucleoprotein TPR; Megator; NPC-associated intranuclear protein; Translocated promoter region protein", "protein_names_refseq": "nucleoprotein TPR isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100753776)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017056 structural constituent of nuclear pore", "go_cellular_component": "GO:0044615 nuclear pore nuclear basket;GO:0005819 spindle;GO:0031965 nuclear membrane;GO:0000776 kinetochore;GO:0034399 nuclear periphery", "go_biological_process": "GO:0006406 mRNA export from nucleus;GO:0051301 cell division;GO:0090316 positive regulation of intracellular protein transport;GO:1901673 regulation of mitotic spindle assembly;GO:0006606 protein import into nucleus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G0I3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G0Z7-1", "uniprot_id": [ { "id": "A0A9J7G0Z7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G0Z7", "type": "external" } ], "mass": 51301.0, "length": 464, "protein_name": "Chitotriosidase-1", "gene_name": "Chit1", "organism": "Hamster", "refseq_name": "chitotriosidase-1 isoform X1", "refseq_ac": [ { "id": "XP_027273371", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273371", "type": "external" } ], "gene_names_uniprotkb": "Chit1", "gene_names_refseq": "Chit1", "protein_names_uniprotkb": "Chitotriosidase-1; 3.2.1.14; Chitinase-1", "protein_names_refseq": "chitotriosidase-1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100750757)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027273371.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008843 endochitinase activity;GO:0008061 chitin binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005764 lysosome", "go_biological_process": "GO:0000272 polysaccharide catabolic process;GO:0006032 chitin catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G0Z7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G1A0-1", "uniprot_id": [ { "id": "A0A9J7G1A0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G1A0", "type": "external" } ], "mass": 106674.0, "length": 933, "protein_name": "Tyrosine-protein phosphatase non-receptor type", "gene_name": "Ptpn4", "organism": "Hamster", "refseq_name": "tyrosine-protein phosphatase non-receptor type 4 isoform X1", "refseq_ac": [ { "id": "XP_027273598", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273598", "type": "external" } ], "gene_names_uniprotkb": "Ptpn4", "gene_names_refseq": "Ptpn4", "protein_names_uniprotkb": "Tyrosine-protein phosphatase non-receptor type; 3.1.3.48", "protein_names_refseq": "tyrosine-protein phosphatase non-receptor type 4 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100757007)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May act at junctions between the membrane and the cytoskeleton., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" } ], "go_molecular_function": "GO:0008092 cytoskeletal protein binding;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G1A0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G180-1", "uniprot_id": [ { "id": "A0A9J7G180_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G180", "type": "external" } ], "mass": 105379.0, "length": 932, "protein_name": "Dual serine/threonine and tyrosine protein kinase", "gene_name": "Dstyk", "organism": "Hamster", "refseq_name": "dual serine/threonine and tyrosine protein kinase isoform X2", "refseq_ac": [ { "id": "XP_027273431", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273431", "type": "external" } ], "gene_names_uniprotkb": "Dstyk", "gene_names_refseq": "Dstyk", "protein_names_uniprotkb": "Dual serine/threonine and tyrosine protein kinase; 2.7.12.1; Dusty protein kinase; Receptor-interacting serine/threonine-protein kinase 5", "protein_names_refseq": "dual serine/threonine and tyrosine protein kinase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100759895)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. Involved in the regulation of both caspase-dependent apoptosis and caspase-independent cell death. In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0004712 protein serine/threonine/tyrosine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane;GO:0070161 anchoring junction", "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0044344 cellular response to fibroblast growth factor stimulus;GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G180-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G1B8-1", "uniprot_id": [ { "id": "A0A9J7G1B8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G1B8", "type": "external" } ], "mass": 183709.0, "length": 1700, "protein_name": "protein-serine/threonine phosphatase", "gene_name": "Phlpp1", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: PH domain leucine-rich repeat-containing protein phosphatase 1 isoform X2", "refseq_ac": [ { "id": "XP_027273661", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273661", "type": "external" } ], "gene_names_uniprotkb": "Phlpp1", "gene_names_refseq": "Phlpp1", "protein_names_uniprotkb": "protein-serine/threonine phosphatase; 3.1.3.16; Pleckstrin homology domain-containing family E member 1; Suprachiasmatic nucleus circadian oscillatory protein", "protein_names_refseq": "LOW QUALITY PROTEIN: PH domain leucine-rich repeat-containing protein phosphatase 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100750559)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 4 indels ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027273661.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.52", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.52", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.74", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.74", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G1B8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G1H0-1", "uniprot_id": [ { "id": "A0A9J7G1H0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G1H0", "type": "external" } ], "mass": 95107.0, "length": 846, "protein_name": "Mitogen-activated protein kinase kinase kinase kinase", "gene_name": "Map4k5", "organism": "Hamster", "refseq_name": "mitogen-activated protein kinase kinase kinase kinase 5 isoform X1", "refseq_ac": [ { "id": "XP_003515588", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003515588", "type": "external" } ], "gene_names_uniprotkb": "Map4k5", "gene_names_refseq": "Map4k5", "protein_names_uniprotkb": "Mitogen-activated protein kinase kinase kinase kinase; 2.7.11.1", "protein_names_refseq": "mitogen-activated protein kinase kinase kinase kinase 5 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100764523)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 4176 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003618383.1) and transcript sequence (IACG01045610.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003515588.3. COMPLETENESS: full length., [RefSeq]; Serine/threonine kinase that plays a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008349 MAP kinase kinase kinase kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G1H0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G1K8-1", "uniprot_id": [ { "id": "A0A9J7G1K8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G1K8", "type": "external" } ], "mass": 201778.0, "length": 1766, "protein_name": "Sodium channel protein", "gene_name": "Scn11a", "organism": "Hamster", "refseq_name": "sodium channel protein type 11 subunit alpha", "refseq_ac": [ { "id": "XP_003505988", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505988", "type": "external" } ], "gene_names_uniprotkb": "Scn11a", "gene_names_refseq": "Scn11a", "protein_names_uniprotkb": "Sodium channel protein", "protein_names_refseq": "sodium channel protein type 11 subunit alpha", "tax_id": 10029, "disease": "", "pathway": " (cge:100755682)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614199.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient., [UniProtKB, UniProtKB]; Sodium channel mediating the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. Involved in membrane depolarization during action potential in nociceptors which function as key relay stations for the electrical transmission of pain signals from the periphery to the central nervous system. Also involved in rapid BDNF-evoked neuronal depolarization., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005248 voltage-gated sodium channel activity", "go_cellular_component": "GO:0001518 voltage-gated sodium channel complex", "go_biological_process": "GO:0019228 neuronal action potential;GO:0086010 membrane depolarization during action potential", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G1K8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G1P6-1", "uniprot_id": [ { "id": "A0A9J7G1P6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G1P6", "type": "external" } ], "mass": 78588.0, "length": 703, "protein_name": "Lutropin-choriogonadotropic hormone receptor", "gene_name": "Lhcgr", "organism": "Hamster", "refseq_name": "lutropin-choriogonadotropic hormone receptor isoform X2", "refseq_ac": [ { "id": "XP_027273807", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273807", "type": "external" } ], "gene_names_uniprotkb": "Lhcgr; LHCGR", "gene_names_refseq": "Lhcgr", "protein_names_uniprotkb": "Lutropin-choriogonadotropic hormone receptor", "protein_names_refseq": "lutropin-choriogonadotropic hormone receptor isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772530)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042562 hormone binding;GO:0008528 G protein-coupled peptide receptor activity;GO:0004964 luteinizing hormone receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0008584 male gonad development;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0009755 hormone-mediated signaling pathway;GO:0001541 ovarian follicle development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G1P6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G3Y9-1", "uniprot_id": [ { "id": "A0A9J7G3Y9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G3Y9", "type": "external" } ], "mass": 787928.0, "length": 6911, "protein_name": "Nesprin-2", "gene_name": "Syne2", "organism": "Hamster", "refseq_name": "nesprin-2 isoform X1", "refseq_ac": [ { "id": "XP_027274066", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274066", "type": "external" } ], "gene_names_uniprotkb": "Syne2", "gene_names_refseq": "Syne2", "protein_names_uniprotkb": "Nesprin-2; KASH domain-containing protein 2; Nuclear envelope spectrin repeat protein 2; Nucleus and actin connecting element protein; Synaptic nuclear envelope protein 2", "protein_names_refseq": "nesprin-2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100767452)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005739 mitochondrion;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0030018 Z disc", "go_biological_process": "GO:1902017 regulation of cilium assembly;GO:0051642 centrosome localization;GO:0007097 nuclear migration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G3Y9-1", "record_type": "protein", "filter_code": "0000000.0000101.000010.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G1Y0-1", "uniprot_id": [ { "id": "A0A9J7G1Y0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G1Y0", "type": "external" } ], "mass": 260865.0, "length": 2274, "protein_name": "DNA polymerase epsilon catalytic subunit", "gene_name": "Pole", "organism": "Hamster", "refseq_name": "DNA polymerase epsilon catalytic subunit A isoform X1", "refseq_ac": [ { "id": "XP_007640562", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640562", "type": "external" } ], "gene_names_uniprotkb": "Pole", "gene_names_refseq": "Pole", "protein_names_uniprotkb": "DNA polymerase epsilon catalytic subunit; 2.7.7.7", "protein_names_refseq": "DNA polymerase epsilon catalytic subunit A isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100774671)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 105 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613859.1) and transcript sequence (IACG01045752.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007640562.2. COMPLETENESS: full length., [RefSeq]; DNA polymerase II participates in chromosomal DNA replication., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.31", "type": "external" }, { "id": "2.7.7.102", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.102", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" } ], "go_molecular_function": "GO:0003887 DNA-directed DNA polymerase activity;GO:0008310 single-stranded DNA 3'-5' DNA exonuclease activity;GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0051539 4 iron, 4 sulfur cluster binding", "go_cellular_component": "GO:0008622 epsilon DNA polymerase complex", "go_biological_process": "GO:0006272 leading strand elongation;GO:0006297 nucleotide-excision repair, DNA gap filling;GO:0006287 base-excision repair, gap-filling;GO:0045004 DNA replication proofreading;GO:0000278 mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G1Y0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G243-1", "uniprot_id": [ { "id": "A0A9J7G243_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G243", "type": "external" } ], "mass": 44150.0, "length": 396, "protein_name": "Protein phosphatase 1A", "gene_name": "Ppm1a", "organism": "Hamster", "refseq_name": "protein phosphatase 1A", "refseq_ac": [ { "id": "XP_027240247", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240247", "type": "external" } ], "gene_names_uniprotkb": "Ppm1a", "gene_names_refseq": "Ppm1a", "protein_names_uniprotkb": "Protein phosphatase 1A; 3.1.3.16; Protein phosphatase 2C isoform alpha; Protein phosphatase IA", "protein_names_refseq": "protein phosphatase 1A", "tax_id": 10029, "disease": "", "pathway": " (cge:100773654)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615418.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027240247.1. COMPLETENESS: full length., [RefSeq]; Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination of TNF-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.52", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.52", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.74", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.74", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0030145 manganese ion binding;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G243-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G257-1", "uniprot_id": [ { "id": "A0A9J7G257_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G257", "type": "external" } ], "mass": 59420.0, "length": 549, "protein_name": "Choline/ethanolamine transporter FLVCR1", "gene_name": "Flvcr1", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: feline leukemia virus subgroup C receptor-related protein 1 isoform X2", "refseq_ac": [ { "id": "XP_027274495", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274495", "type": "external" } ], "gene_names_uniprotkb": "Flvcr1", "gene_names_refseq": "Flvcr1", "protein_names_uniprotkb": "Choline/ethanolamine transporter FLVCR1; Feline leukemia virus subgroup C receptor-related protein 1; Heme transporter FLVCR1", "protein_names_refseq": "LOW QUALITY PROTEIN: feline leukemia virus subgroup C receptor-related protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100766724)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Uniporter that mediates the transport of extracellular choline and ethanolamine into cells, thereby playing a key role in phospholipid biosynthesis. Choline and ethanolamine are the precursors of phosphatidylcholine and phosphatidylethanolamine, respectively, the two most abundant phospholipids. Transport is not coupled with proton transport and is exclusively driven by the choline (or ethanolamine) gradient across the plasma membrane. Also acts as a heme b transporter that mediates heme efflux from the cytoplasm to the extracellular compartment., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015232 heme transmembrane transporter activity;GO:0020037 heme binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0043249 erythrocyte maturation;GO:0006839 mitochondrial transport;GO:0006783 heme biosynthetic process;GO:0097037 heme export", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G257-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G2B2-1", "uniprot_id": [ { "id": "A0A9J7G2B2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G2B2", "type": "external" } ], "mass": 90013.0, "length": 841, "protein_name": "Protein enabled homolog", "gene_name": "Enah", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: protein enabled homolog isoform X2", "refseq_ac": [ { "id": "XP_027274602", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274602", "type": "external" } ], "gene_names_uniprotkb": "Enah", "gene_names_refseq": "Enah", "protein_names_uniprotkb": "Protein enabled homolog", "protein_names_refseq": "LOW QUALITY PROTEIN: protein enabled homolog isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100752970)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. ENAH induces the formation of F-actin rich outgrowths in fibroblasts. Acts synergistically with BAIAP2-alpha and downstream of NTN1 to promote filipodia formation., [UniProtKB, UniProtKB]", "predicted_glycosites": 6, "predicted_n_glycosites": 0, "predicted_o_glycosites": 6, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0017124 SH3 domain binding;GO:0005522 profilin binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0005925 focal adhesion;GO:0030027 lamellipodium;GO:0045202 synapse", "go_biological_process": "GO:0070358 actin polymerization-dependent cell motility;GO:0008154 actin polymerization or depolymerization;GO:0007411 axon guidance", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G2B2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G483-1", "uniprot_id": [ { "id": "A0A9J7G483_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G483", "type": "external" } ], "mass": 69716.0, "length": 617, "protein_name": "Lysosomal cobalamin transporter ABCD4", "gene_name": "Abcd4", "organism": "Hamster", "refseq_name": "lysosomal cobalamin transporter ABCD4 isoform X3", "refseq_ac": [ { "id": "XP_027274313", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274313", "type": "external" } ], "gene_names_uniprotkb": "Abcd4", "gene_names_refseq": "Abcd4", "protein_names_uniprotkb": "Lysosomal cobalamin transporter ABCD4; 7.6.2.8; ATP-binding cassette sub-family D member 4; PMP70-related protein; Peroxisomal membrane protein 1-like; Peroxisomal membrane protein 69", "protein_names_refseq": "lysosomal cobalamin transporter ABCD4 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100768387)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Lysosomal membrane protein that transports cobalamin (Vitamin B12) from the lysosomal lumen to the cytosol in an ATP-dependent manner. Targeted by LMBRD1 lysosomal chaperone from the endoplasmic reticulum to the lysosomal membrane. Then forms a complex with lysosomal chaperone LMBRD1 and cytosolic MMACHC to transport cobalamin across the lysosomal membrane., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "7.6.2.8", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.8", "type": "external" } ], "go_molecular_function": "GO:0005324 long-chain fatty acid transmembrane transporter activity;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0015420 ABC-type vitamin B12 transporter activity;GO:0140359 ABC-type transporter activity", "go_cellular_component": "GO:0005778 peroxisomal membrane;GO:0005765 lysosomal membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006635 fatty acid beta-oxidation;GO:0042760 very long-chain fatty acid catabolic process;GO:0007031 peroxisome organization;GO:0015910 long-chain fatty acid import into peroxisome;GO:0009235 cobalamin metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G483-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G2E9-1", "uniprot_id": [ { "id": "A0A9J7G2E9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G2E9", "type": "external" } ], "mass": 60898.0, "length": 562, "protein_name": "Choline/ethanolamine transporter FLVCR2", "gene_name": "Flvcr2", "organism": "Hamster", "refseq_name": "feline leukemia virus subgroup C receptor-related protein 2", "refseq_ac": [ { "id": "XP_003502833", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502833", "type": "external" } ], "gene_names_uniprotkb": "Flvcr2", "gene_names_refseq": "Flvcr2", "protein_names_uniprotkb": "Choline/ethanolamine transporter FLVCR2; Calcium-chelate transporter; Feline leukemia virus subgroup C receptor-related protein 2; Heme transporter FLVCR2", "protein_names_refseq": "feline leukemia virus subgroup C receptor-related protein 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100760195)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613913.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015232 heme transmembrane transporter activity;GO:0020037 heme binding;GO:0015220 choline transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0031966 mitochondrial membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0097037 heme export", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G2E9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G2K3-1", "uniprot_id": [ { "id": "A0A9J7G2K3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G2K3", "type": "external" } ], "mass": 126692.0, "length": 1155, "protein_name": "Integrin alpha-9", "gene_name": "Itga9", "organism": "Hamster", "refseq_name": "integrin alpha-9 isoform X2", "refseq_ac": [ { "id": "XP_027271146", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271146", "type": "external" } ], "gene_names_uniprotkb": "Itga9", "gene_names_refseq": "Itga9", "protein_names_uniprotkb": "Integrin alpha-9", "protein_names_refseq": "integrin alpha-9 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754465)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 10% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Integrin alpha-9/beta-1 (ITGA9:ITGB1) is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. ITGA9:ITGB1 may play a crucial role in SVEP1/polydom-mediated myoblast cell adhesion. Integrin ITGA9:ITGB1 represses PRKCA-mediated L-type voltage-gated channel Ca(2+) influx and ROCK-mediated calcium sensitivity in vascular smooth muscle cells via its interaction with SVEP1, thereby inhibiting vasocontraction., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0009897 external side of plasma membrane;GO:0034679 integrin alpha9-beta1 complex", "go_biological_process": "GO:0007229 integrin-mediated signaling pathway;GO:0007160 cell-matrix adhesion;GO:0033627 cell adhesion mediated by integrin;GO:0098609 cell-cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G2K3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G319-1", "uniprot_id": [ { "id": "A0A9J7G319_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G319", "type": "external" } ], "mass": 74206.0, "length": 659, "protein_name": "Lamin-B2", "gene_name": "Lmnb2", "organism": "Hamster", "refseq_name": "lamin-B2 isoform X2", "refseq_ac": [ { "id": "XP_027275097", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275097", "type": "external" } ], "gene_names_uniprotkb": "Lmnb2", "gene_names_refseq": "Lmnb2", "protein_names_uniprotkb": "Lamin-B2", "protein_names_refseq": "lamin-B2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100766421)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Lamins are intermediate filament proteins that assemble into a filamentous meshwork, and which constitute the major components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane. Lamins provide a framework for the nuclear envelope, bridging the nuclear envelope and chromatin, thereby playing an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. The structural integrity of the lamina is strictly controlled by the cell cycle, as seen by the disintegration and formation of the nuclear envelope in prophase and telophase, respectively., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005200 structural constituent of cytoskeleton", "go_cellular_component": "GO:0005882 intermediate filament;GO:0005652 nuclear lamina", "go_biological_process": "GO:0090435 protein localization to nuclear envelope;GO:0006998 nuclear envelope organization;GO:0031507 heterochromatin formation;GO:0007097 nuclear migration;GO:0051664 nuclear pore localization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G319-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G3C1-1", "uniprot_id": [ { "id": "A0A9J7G3C1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G3C1", "type": "external" } ], "mass": 55589.0, "length": 487, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Dapk3", "organism": "Hamster", "refseq_name": "death-associated protein kinase 3 isoform X5", "refseq_ac": [ { "id": "XP_027275073", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275073", "type": "external" } ], "gene_names_uniprotkb": "Dapk3", "gene_names_refseq": "Dapk3", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "death-associated protein kinase 3 isoform X5", "tax_id": 10029, "disease": "", "pathway": " (cge:100773624)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0043065 positive regulation of apoptotic process;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G3C1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G3B4-1", "uniprot_id": [ { "id": "A0A9J7G3B4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G3B4", "type": "external" } ], "mass": 31151.0, "length": 286, "protein_name": "Transmembrane protein 163", "gene_name": "Tmem163", "organism": "Hamster", "refseq_name": "transmembrane protein 163 isoform X2", "refseq_ac": [ { "id": "XP_027273568", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273568", "type": "external" } ], "gene_names_uniprotkb": "Tmem163", "gene_names_refseq": "Tmem163", "protein_names_uniprotkb": "Transmembrane protein 163; Synaptic vesicle membrane protein of 31 kDa", "protein_names_refseq": "transmembrane protein 163 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100761336)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Zinc ion transporter that mediates zinc efflux and plays a crucial role in intracellular zinc homeostasis. Binds the divalent cations Zn(2+), Ni(2+), and to a minor extent Cu(2+). Is a functional modulator of P2X purinoceptors, including P2RX1, P2RX3, P2RX4 and P2RX7. Plays a role in central nervous system development and is required for myelination, and survival and proliferation of oligodendrocytes., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0031901 early endosome membrane;GO:0030672 synaptic vesicle membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G3B4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G3C9-1", "uniprot_id": [ { "id": "A0A9J7G3C9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G3C9", "type": "external" } ], "mass": 79767.0, "length": 688, "protein_name": "G protein-coupled receptor kinase", "gene_name": "LOC100761290", "organism": "Hamster", "refseq_name": "beta-adrenergic receptor kinase 2 isoform X3", "refseq_ac": [ { "id": "XP_027271749", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271749", "type": "external" } ], "gene_names_uniprotkb": "LOC100761290", "gene_names_refseq": "LOC100761290", "protein_names_uniprotkb": "G protein-coupled receptor kinase; 2.7.11.-", "protein_names_refseq": "beta-adrenergic receptor kinase 2 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100761290)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; receptors. Also phosphorylates ligand-bound C3a and C5a anaphylatoxin receptors (C3AR1 and C5AR1, respectively), leading to receptor desensitization., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0001664 G protein-coupled receptor binding;GO:0004703 G protein-coupled receptor kinase activity;GO:0047696 beta-adrenergic receptor kinase activity", "go_cellular_component": "GO:0098793 presynapse", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0002029 desensitization of G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G3C9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G3E5-1", "uniprot_id": [ { "id": "A0A9J7G3E5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G3E5", "type": "external" } ], "mass": 250792.0, "length": 2348, "protein_name": "Adenomatous polyposis coli protein 2", "gene_name": "Apc2", "organism": "Hamster", "refseq_name": "adenomatous polyposis coli protein 2 isoform X2", "refseq_ac": [ { "id": "XP_027275165", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275165", "type": "external" } ], "gene_names_uniprotkb": "Apc2", "gene_names_refseq": "Apc2", "protein_names_uniprotkb": "Adenomatous polyposis coli protein 2", "protein_names_refseq": "adenomatous polyposis coli protein 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767273)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027275165.1. COMPLETENESS: full length., [RefSeq]; Stabilizes microtubules and may regulate actin fiber dynamics through the activation of Rho family GTPases. May also function in Wnt signaling by promoting the rapid degradation of CTNNB1., [UniProtKB, UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding;GO:0008013 beta-catenin binding;GO:0045295 gamma-catenin binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0048471 perinuclear region of cytoplasm;GO:0016342 catenin complex;GO:0030877 beta-catenin destruction complex;GO:0005881 cytoplasmic microtubule", "go_biological_process": "GO:0001708 cell fate specification;GO:0007399 nervous system development;GO:0016477 cell migration;GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0016055 Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G3E5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G3J3-1", "uniprot_id": [ { "id": "A0A9J7G3J3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G3J3", "type": "external" } ], "mass": 47484.0, "length": 422, "protein_name": "Bardet-Biedl syndrome 5 protein homolog", "gene_name": "Bbs5", "organism": "Hamster", "refseq_name": "Bardet-Biedl syndrome 5 protein", "refseq_ac": [ { "id": "XP_003495983", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495983", "type": "external" } ], "gene_names_uniprotkb": "Bbs5", "gene_names_refseq": "Bbs5", "protein_names_uniprotkb": "Bardet-Biedl syndrome 5 protein homolog", "protein_names_refseq": "Bardet-Biedl syndrome 5 protein", "tax_id": 10029, "disease": "", "pathway": " (cge:100762765)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613606.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003495983.1. COMPLETENESS: full length., [RefSeq]; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for BBSome complex ciliary localization but not for the proper complex assembly., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0032266 phosphatidylinositol-3-phosphate binding", "go_cellular_component": "GO:0034451 centriolar satellite;GO:0036064 ciliary basal body;GO:0060170 ciliary membrane;GO:0034464 BBSome", "go_biological_process": "GO:0015031 protein transport;GO:0060271 cilium assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G3J3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G4M9-1", "uniprot_id": [ { "id": "A0A9J7G4M9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G4M9", "type": "external" } ], "mass": 226337.0, "length": 2000, "protein_name": "Sodium channel protein", "gene_name": "Scn3a", "organism": "Hamster", "refseq_name": "sodium channel protein type 3 subunit alpha isoform X1", "refseq_ac": [ { "id": "XP_003501508", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501508", "type": "external" } ], "gene_names_uniprotkb": "Scn3a", "gene_names_refseq": "Scn3a", "protein_names_uniprotkb": "Sodium channel protein", "protein_names_refseq": "sodium channel protein type 3 subunit alpha isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100767559)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613851.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005248 voltage-gated sodium channel activity", "go_cellular_component": "GO:0001518 voltage-gated sodium channel complex", "go_biological_process": "GO:0019228 neuronal action potential;GO:0086010 membrane depolarization during action potential", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G4M9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G402-1", "uniprot_id": [ { "id": "A0A9J7G402_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G402", "type": "external" } ], "mass": 225737.0, "length": 1971, "protein_name": "Dedicator of cytokinesis protein 4", "gene_name": "Dock4", "organism": "Hamster", "refseq_name": "dedicator of cytokinesis protein 4 isoform X2", "refseq_ac": [ { "id": "XP_027275522", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275522", "type": "external" } ], "gene_names_uniprotkb": "Dock4", "gene_names_refseq": "Dock4", "protein_names_uniprotkb": "Dedicator of cytokinesis protein 4", "protein_names_refseq": "dedicator of cytokinesis protein 4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772385)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Functions as a guanine nucleotide exchange factor (GEF) that promotes the exchange of GDP to GTP, converting inactive GDP-bound small GTPases into their active GTP-bound form. Involved in regulation of adherens junction between cells. Plays a role in cell migration., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Has a higher guanine nucleotide exchange factor activity compared to other isoforms., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0017124 SH3 domain binding;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0043226 organelle", "go_biological_process": "GO:0007264 small GTPase-mediated signal transduction;GO:0060326 cell chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G402-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G3Z4-1", "uniprot_id": [ { "id": "A0A9J7G3Z4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G3Z4", "type": "external" } ], "mass": 137743.0, "length": 1257, "protein_name": "ATP-binding cassette sub-family B member 5", "gene_name": "LOC100770292", "organism": "Hamster", "refseq_name": "ATP-binding cassette sub-family B member 5 isoform X3", "refseq_ac": [ { "id": "XP_027272219", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272219", "type": "external" } ], "gene_names_uniprotkb": "LOC100770292", "gene_names_refseq": "LOC100770292", "protein_names_uniprotkb": "ATP-binding cassette sub-family B member 5; 7.6.2.2; ABCB5 P-gp; p-glycoprotein ABCB5", "protein_names_refseq": "ATP-binding cassette sub-family B member 5 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100770292)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Energy-dependent efflux transporter responsible for decreased drug accumulation in multidrug-resistant cells. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008559 ABC-type xenobiotic transporter activity;GO:0016887 ATP hydrolysis activity;GO:0015421 ABC-type oligopeptide transporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0030154 cell differentiation;GO:0090374 oligopeptide export from mitochondrion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G3Z4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G412-1", "uniprot_id": [ { "id": "A0A9J7G412_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G412", "type": "external" } ], "mass": 327976.0, "length": 2914, "protein_name": "3'-5' exoribonuclease HELZ2", "gene_name": "Helz2", "organism": "Hamster", "refseq_name": "helicase with zinc finger domain 2", "refseq_ac": [ { "id": "XP_027275747", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275747", "type": "external" } ], "gene_names_uniprotkb": "Helz2", "gene_names_refseq": "Helz2", "protein_names_uniprotkb": "3'-5' exoribonuclease HELZ2; 3.1.13.1; 3.6.4.13; ATP-dependent RNA helicase PRIC285; PPAR-gamma DNA-binding domain-interacting protein 1", "protein_names_refseq": "helicase with zinc finger domain 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767179)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Can degrade highly structured RNAs through its concerted ATP-dependent RNA helicase and 3' to 5' exoribonuclease activities. Shows a strong preference for pyrimidine over purine residues for its nuclease activity. Acts as a transcriptional coactivator for a number of nuclear receptors including PPARA, PPARG, THRA, THRB and RXRA., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0008859 exoribonuclease II activity;GO:0003677 DNA binding;GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G412-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G454-1", "uniprot_id": [ { "id": "A0A9J7G454_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G454", "type": "external" } ], "mass": 181633.0, "length": 1625, "protein_name": "Kinesin-like protein KIF21B", "gene_name": "Kif21b", "organism": "Hamster", "refseq_name": "kinesin-like protein KIF21B", "refseq_ac": [ { "id": "XP_027273289", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273289", "type": "external" } ], "gene_names_uniprotkb": "Kif21b", "gene_names_refseq": "Kif21b", "protein_names_uniprotkb": "Kinesin-like protein KIF21B", "protein_names_refseq": "kinesin-like protein KIF21B", "tax_id": 10029, "disease": "", "pathway": " (cge:100766089)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0003777 microtubule motor activity", "go_cellular_component": "GO:0005874 microtubule;GO:0030425 dendrite;GO:0030426 growth cone;GO:0005875 microtubule associated complex", "go_biological_process": "GO:0007018 microtubule-based movement;GO:0007052 mitotic spindle organization;GO:0051231 spindle elongation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G454-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G4F1-1", "uniprot_id": [ { "id": "A0A9J7G4F1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G4F1", "type": "external" } ], "mass": 90680.0, "length": 793, "protein_name": "DnaJ homolog subfamily C member 10", "gene_name": "Dnajc10", "organism": "Hamster", "refseq_name": "dnaJ homolog subfamily C member 10", "refseq_ac": [ { "id": "XP_027275873", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275873", "type": "external" } ], "gene_names_uniprotkb": "Dnajc10", "gene_names_refseq": "Dnajc10", "protein_names_uniprotkb": "DnaJ homolog subfamily C member 10; 1.8.4.-", "protein_names_refseq": "dnaJ homolog subfamily C member 10", "tax_id": 10029, "disease": "", "pathway": " (cge:100689230)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Endoplasmic reticulum disulfide reductase that collaborates directly with a BIP/HSPA5 (GRP78)-type chaperone to maintain protein quality control by facilitating either the correct folding or the targeted degradation of misfolded proteins., [UniProtKB, UniProtKB]; Endoplasmic reticulum disulfide reductase that collaborates directly with the chaperone BIP/HSPA5 (GRP78) to maintain protein quality control by facilitating either the correct folding or the targeted degradation of misfolded proteins. Essential for efficient maturation of newly synthesized polypeptides in the endoplasmic reticulum, binds to substrate proteins and specifically catalyzes the reduction and removal of improper (non-native) disulfide bonds during the folding process. In endoplasmic reticulum-associated degradation (ERAD), DNAJC10 reduces incorrect disulfide bonds specifically in misfolded glycoproteins that have been recognized by EDEM1, a key component of the ERAD pathway, thereby enabling their retrotranslocation and degradation. Promotes apoptotic signaling pathway in response to endoplasmic reticulum stress., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.8.4.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.4.2", "type": "external" }, { "id": "1.8.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.4.-", "type": "external" } ], "go_molecular_function": "GO:0051087 protein-folding chaperone binding;GO:0051117 ATPase binding;GO:0015035 protein-disulfide reductase activity;GO:0051787 misfolded protein binding;GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor", "go_cellular_component": "GO:0005788 endoplasmic reticulum lumen", "go_biological_process": "GO:0036498 IRE1-mediated unfolded protein response;GO:0036503 ERAD pathway;GO:0034975 protein folding in endoplasmic reticulum", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G4F1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G4I9-1", "uniprot_id": [ { "id": "A0A9J7G4I9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G4I9", "type": "external" } ], "mass": 121879.0, "length": 1091, "protein_name": "Integrin alpha-6", "gene_name": "Itga6", "organism": "Hamster", "refseq_name": "integrin alpha-6 isoform X1", "refseq_ac": [ { "id": "XP_027275995", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275995", "type": "external" } ], "gene_names_uniprotkb": "Itga6", "gene_names_refseq": "Itga6", "protein_names_uniprotkb": "Integrin alpha-6; CD49 antigen-like family member F; VLA-6", "protein_names_refseq": "integrin alpha-6 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100769534)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Integrin alpha-6/beta-1 (ITGA6:ITGB1) is a receptor for laminin on platelets. Integrin alpha-6/beta-1 (ITGA6:ITGB1) is present in oocytes and is involved in sperm-egg fusion. Integrin alpha-6/beta-4 (ITGA6:ITGB4) is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling. ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0009897 external side of plasma membrane;GO:0008305 integrin complex", "go_biological_process": "GO:0007229 integrin-mediated signaling pathway;GO:0007160 cell-matrix adhesion;GO:0033627 cell adhesion mediated by integrin;GO:0098609 cell-cell adhesion;GO:0050900 leukocyte migration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G4I9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G4N0-1", "uniprot_id": [ { "id": "A0A9J7G4N0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G4N0", "type": "external" } ], "mass": 257282.0, "length": 2300, "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "Ubr3", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase UBR3 isoform X4", "refseq_ac": [ { "id": "XP_027276276", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276276", "type": "external" } ], "gene_names_uniprotkb": "Ubr3", "gene_names_refseq": "Ubr3", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase; 2.3.2.27", "protein_names_refseq": "E3 ubiquitin-protein ligase UBR3 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100772607)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 16% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Does not bind to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. May play a role in Shh signaling by mediating the ubiquitination of Kif7. May be important for MYH9 function in certain tissues, possibly by regulating the ubiquitination of MYH9 and consequently affecting its interaction with MYO7A., [UniProtKB, UniProtKB]; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0000151 ubiquitin ligase complex", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G4N0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G4N1-1", "uniprot_id": [ { "id": "A0A9J7G4N1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G4N1", "type": "external" } ], "mass": 191488.0, "length": 1668, "protein_name": "Sodium channel protein", "gene_name": "Scn7a", "organism": "Hamster", "refseq_name": "sodium channel protein type 7 subunit alpha isoform X2", "refseq_ac": [ { "id": "XP_027276062", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276062", "type": "external" } ], "gene_names_uniprotkb": "Scn7a", "gene_names_refseq": "Scn7a", "protein_names_uniprotkb": "Sodium channel protein", "protein_names_refseq": "sodium channel protein type 7 subunit alpha isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100751078)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient., [UniProtKB, UniProtKB]; Sodium leak channel functioning as an osmosensor regulating sodium ion levels in various tissues and organs. While most sodium channels are voltage-gated, SCN7A is not and lets sodium flow through membrane along its concentration gradient. In glial cells of the central nervous system, senses body-fluid sodium levels and controls salt intake behavior as well as voluntary water intake through activation of nearby neurons to maintain appropriate sodium levels in the body. By mediating sodium influx into keratinocytes, also plays a role in skin barrier homeostasis., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005248 voltage-gated sodium channel activity;GO:1990760 osmolarity-sensing monoatomic cation channel activity", "go_cellular_component": "GO:0001518 voltage-gated sodium channel complex", "go_biological_process": "GO:0055078 sodium ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G4N1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G4P5-1", "uniprot_id": [ { "id": "A0A9J7G4P5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G4P5", "type": "external" } ], "mass": 33254.0, "length": 283, "protein_name": "Sphingolipid delta(4)-desaturase DES1", "gene_name": "LOC100760423", "organism": "Hamster", "refseq_name": "sphingolipid delta(4)-desaturase DES1 isoform X2", "refseq_ac": [ { "id": "XP_027274630", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274630", "type": "external" } ], "gene_names_uniprotkb": "LOC100760423", "gene_names_refseq": "LOC100760423", "protein_names_uniprotkb": "Sphingolipid delta(4)-desaturase DES1; Degenerative spermatocyte homolog 1; Dihydroceramide desaturase-1; Retinol isomerase", "protein_names_refseq": "sphingolipid delta(4)-desaturase DES1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100760423)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine). Catalyzes the equilibrium isomerization of retinols., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.19.17", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.19.17", "type": "external" } ], "go_molecular_function": "GO:0016853 isomerase activity;GO:0042284 sphingolipid delta-4 desaturase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0046513 ceramide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G4P5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G4T5-1", "uniprot_id": [ { "id": "A0A9J7G4T5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G4T5", "type": "external" } ], "mass": 162050.0, "length": 1521, "protein_name": "Formin-2", "gene_name": "Fmn2", "organism": "Hamster", "refseq_name": "formin-2 isoform X1", "refseq_ac": [ { "id": "XP_027274709", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274709", "type": "external" } ], "gene_names_uniprotkb": "Fmn2", "gene_names_refseq": "Fmn2", "protein_names_uniprotkb": "Formin-2", "protein_names_refseq": "formin-2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100770806)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Actin-binding protein that is involved in actin cytoskeleton assembly and reorganization. Acts as an actin nucleation factor and promotes assembly of actin filaments together with SPIRE1 and SPIRE2. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning, asymmetric oocyte division and polar body extrusion during female germ cell meiosis. Plays a role in responses to DNA damage, cellular stress and hypoxia by protecting CDKN1A against degradation, and thereby plays a role in stress-induced cell cycle arrest. Also acts in the nucleus: together with SPIRE1 and SPIRE2, promotes assembly of nuclear actin filaments in response to DNA damage in order to facilitate movement of chromatin and repair factors after DNA damage. Protects cells against apoptosis by protecting CDKN1A against degradation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0005938 cell cortex", "go_biological_process": "GO:0015031 protein transport;GO:0006974 DNA damage response;GO:0030866 cortical actin cytoskeleton organization;GO:0070649 formin-nucleated actin cable assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G4T5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G865-1", "uniprot_id": [ { "id": "A0A9J7G865_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G865", "type": "external" } ], "mass": 116963.0, "length": 1036, "protein_name": "Pre-mRNA-processing factor 40 homolog A", "gene_name": "Prpf40a", "organism": "Hamster", "refseq_name": "pre-mRNA-processing factor 40 homolog A isoform X10", "refseq_ac": [ { "id": "XP_027276222", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276222", "type": "external" } ], "gene_names_uniprotkb": "Prpf40a", "gene_names_refseq": "Prpf40a", "protein_names_uniprotkb": "Pre-mRNA-processing factor 40 homolog A; Formin-binding protein 11; Formin-binding protein 3", "protein_names_refseq": "pre-mRNA-processing factor 40 homolog A isoform X10", "tax_id": 10029, "disease": "", "pathway": " (cge:100774137)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005685 U1 snRNP;GO:0016607 nuclear speck;GO:0016363 nuclear matrix;GO:0071004 U2-type prespliceosome", "go_biological_process": "GO:0045292 mRNA cis splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G865-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G6T6-1", "uniprot_id": [ { "id": "A0A9J7G6T6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G6T6", "type": "external" } ], "mass": 267384.0, "length": 2429, "protein_name": "Telomere-associated protein RIF1", "gene_name": "Rif1", "organism": "Hamster", "refseq_name": "telomere-associated protein RIF1 isoform X7", "refseq_ac": [ { "id": "XP_027276243", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276243", "type": "external" } ], "gene_names_uniprotkb": "Rif1", "gene_names_refseq": "Rif1", "protein_names_uniprotkb": "Telomere-associated protein RIF1; Rap1-interacting factor 1 homolog", "protein_names_refseq": "telomere-associated protein RIF1 isoform X7", "tax_id": 10029, "disease": "", "pathway": " (cge:100771823)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Key regulator of TP53BP1 that plays a key role in the repair of double-strand DNA breaks (DSBs) in response to DNA damage: acts by promoting non-homologous end joining (NHEJ)-mediated repair of DSBs. In response to DNA damage, interacts with ATM-phosphorylated TP53BP1. Interaction with TP53BP1 leads to dissociate the interaction between NUDT16L1/TIRR and TP53BP1, thereby unmasking the tandem Tudor-like domain of TP53BP1 and allowing recruitment to DNA DSBs. Once recruited to DSBs, RIF1 and TP53BP1 act by promoting NHEJ-mediated repair of DSBs. In the same time, RIF1 and TP53BP1 specifically counteract the function of BRCA1 by blocking DSBs resection via homologous recombination (HR) during G1 phase. Also required for immunoglobulin class-switch recombination (CSR) during antibody genesis, a process that involves the generation of DNA DSBs. Promotes NHEJ of dysfunctional telomeres., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005819 spindle;GO:0035861 site of double-strand break;GO:0140445 chromosome, telomeric repeat region", "go_biological_process": "GO:2000042 negative regulation of double-strand break repair via homologous recombination;GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining;GO:0006281 DNA repair;GO:0000723 telomere maintenance", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G6T6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G500-1", "uniprot_id": [ { "id": "A0A9J7G500_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G500", "type": "external" } ], "mass": 311012.0, "length": 2876, "protein_name": "Otogelin", "gene_name": "Otog", "organism": "Hamster", "refseq_name": "otogelin isoform X2", "refseq_ac": [ { "id": "XP_027276343", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276343", "type": "external" } ], "gene_names_uniprotkb": "Otog", "gene_names_refseq": "Otog", "protein_names_uniprotkb": "Otogelin", "protein_names_refseq": "otogelin isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763808)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Glycoprotein specific to acellular membranes of the inner ear. May be required for the anchoring of the otoconial membranes and cupulae to the underlying neuroepithelia in the vestibule. May be involved in the organization and/or stabilization of the fibrillar network that compose the tectorial membrane in the cochlea. May play a role in mechanotransduction processes., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046556 alpha-L-arabinofuranosidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0007399 nervous system development;GO:0046373 L-arabinose metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G500-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G517-1", "uniprot_id": [ { "id": "A0A9J7G517_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G517", "type": "external" } ], "mass": 48895.0, "length": 452, "protein_name": "acid phosphatase", "gene_name": "Acp4", "organism": "Hamster", "refseq_name": "testicular acid phosphatase", "refseq_ac": [ { "id": "XP_027276636", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276636", "type": "external" } ], "gene_names_uniprotkb": "Acp4", "gene_names_refseq": "Acp4", "protein_names_uniprotkb": "acid phosphatase; 3.1.3.2", "protein_names_refseq": "testicular acid phosphatase", "tax_id": 10029, "disease": "", "pathway": " (cge:100757346)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" } ], "go_molecular_function": "GO:0003993 acid phosphatase activity;GO:0030971 receptor tyrosine kinase binding;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0045211 postsynaptic membrane;GO:0005764 lysosome", "go_biological_process": "GO:0007040 lysosome organization;GO:0048168 regulation of neuronal synaptic plasticity;GO:0120154 negative regulation of ERBB4 signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G517-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G541-1", "uniprot_id": [ { "id": "A0A9J7G541_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G541", "type": "external" } ], "mass": 90284.0, "length": 802, "protein_name": "Palmitoyl thioesterase CPT1C", "gene_name": "Cpt1c", "organism": "Hamster", "refseq_name": "carnitine O-palmitoyltransferase 1, brain isoform isoform X2", "refseq_ac": [ { "id": "XP_027276512", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276512", "type": "external" } ], "gene_names_uniprotkb": "Cpt1c", "gene_names_refseq": "Cpt1c", "protein_names_uniprotkb": "Palmitoyl thioesterase CPT1C; 3.1.2.22; Carnitine O-palmitoyltransferase 1, brain isoform; Carnitine palmitoyltransferase 1C; Carnitine palmitoyltransferase I", "protein_names_refseq": "carnitine O-palmitoyltransferase 1, brain isoform isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767138)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion., [UniProtKB, UniProtKB, UniProtKB]; Palmitoyl thioesterase specifically expressed in the endoplasmic reticulum of neurons. Modulates the trafficking of the glutamate receptor, AMPAR, to plasma membrane through depalmitoylation of GRIA1. Also regulates AMPR trafficking through the regulation of SACM1L phosphatidylinositol-3-phosphatase activity by interaction in a malonyl-CoA dependent manner. Binds malonyl-CoA and couples malonyl-CoA to ceramide levels, necessary for proper spine maturation and contributing to systemic energy homeostasis and appetite control. Binds to palmitoyl-CoA, but does not have carnitine palmitoyltransferase 1 catalytic activity or at very low levels., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.2.22", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.22", "type": "external" }, { "id": "2.3.1.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.21", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "3.1.1.93", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.93", "type": "external" }, { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" } ], "go_molecular_function": "GO:0004095 carnitine O-palmitoyltransferase activity;GO:0008474 palmitoyl-(protein) hydrolase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0030424 axon;GO:0030425 dendrite;GO:0005789 endoplasmic reticulum membrane;GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0009437 carnitine metabolic process;GO:0015909 long-chain fatty acid transport;GO:0006635 fatty acid beta-oxidation;GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G541-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G582-1", "uniprot_id": [ { "id": "A0A9J7G582_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G582", "type": "external" } ], "mass": 82714.0, "length": 743, "protein_name": "Amine oxidase", "gene_name": "Il4i1", "organism": "Hamster", "refseq_name": "L-amino-acid oxidase isoform X1", "refseq_ac": [ { "id": "XP_016835382", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016835382", "type": "external" } ], "gene_names_uniprotkb": "Il4i1", "gene_names_refseq": "Il4i1", "protein_names_uniprotkb": "Amine oxidase; 1.4.3.-", "protein_names_refseq": "L-amino-acid oxidase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100773063)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614984.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.4.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.-", "type": "external" } ], "go_molecular_function": "GO:0001716 L-amino-acid oxidase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005764 lysosome;GO:0001669 acrosomal vesicle", "go_biological_process": "GO:0002250 adaptive immune response;GO:0009063 amino acid catabolic process;GO:0045591 positive regulation of regulatory T cell differentiation;GO:0009072 aromatic amino acid metabolic process;GO:0002841 negative regulation of T cell mediated immune response to tumor cell", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G582-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G586-1", "uniprot_id": [ { "id": "A0A9J7G586_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G586", "type": "external" } ], "mass": 130680.0, "length": 1192, "protein_name": "Laminin subunit gamma-2", "gene_name": "Lamc2", "organism": "Hamster", "refseq_name": "laminin subunit gamma-2 isoform X2", "refseq_ac": [ { "id": "XP_027273164", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273164", "type": "external" } ], "gene_names_uniprotkb": "Lamc2", "gene_names_refseq": "Lamc2", "protein_names_uniprotkb": "Laminin subunit gamma-2; Epiligrin subunit gamma; Kalinin subunit gamma; Kalinin/nicein/epiligrin 100 kDa subunit; Laminin B2t chain; Laminin-5 subunit gamma; Nicein subunit gamma", "protein_names_refseq": "laminin subunit gamma-2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100765048)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008201 heparin binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005604 basement membrane", "go_biological_process": "GO:0007155 cell adhesion;GO:0009887 animal organ morphogenesis;GO:0007411 axon guidance;GO:0009888 tissue development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G586-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G5F3-1", "uniprot_id": [ { "id": "A0A9J7G5F3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G5F3", "type": "external" } ], "mass": 79511.0, "length": 718, "protein_name": "Serine/threonine-protein kinase PLK", "gene_name": "Plk5", "organism": "Hamster", "refseq_name": "inactive serine/threonine-protein kinase PLK5 isoform X2", "refseq_ac": [ { "id": "XP_027275155", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275155", "type": "external" } ], "gene_names_uniprotkb": "Plk5", "gene_names_refseq": "Plk5", "protein_names_uniprotkb": "Serine/threonine-protein kinase PLK; 2.7.11.21; Polo-like kinase", "protein_names_refseq": "inactive serine/threonine-protein kinase PLK5 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100757116)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027275155.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0000922 spindle pole;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0000776 kinetochore", "go_biological_process": "GO:0006974 DNA damage response;GO:0007052 mitotic spindle organization;GO:2000045 regulation of G1/S transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G5F3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G5L5-1", "uniprot_id": [ { "id": "A0A9J7G5L5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G5L5", "type": "external" } ], "mass": 53471.0, "length": 505, "protein_name": "Mitochondrial antiviral-signaling protein", "gene_name": "Mavs", "organism": "Hamster", "refseq_name": "mitochondrial antiviral-signaling protein isoform X1", "refseq_ac": [ { "id": "XP_027277550", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277550", "type": "external" } ], "gene_names_uniprotkb": "Mavs", "gene_names_refseq": "Mavs", "protein_names_uniprotkb": "Mitochondrial antiviral-signaling protein; Interferon beta promoter stimulator protein 1; Virus-induced-signaling adapter", "protein_names_refseq": "mitochondrial antiviral-signaling protein isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100764931)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Adapter required for innate immune defense against viruses. Acts downstream of DHX33, RIGI and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). Peroxisomal and mitochondrial MAVS act sequentially to create an antiviral cellular state. Upon viral infection, peroxisomal MAVS induces the rapid interferon-independent expression of defense factors that provide short-term protection, whereas mitochondrial MAVS activates an interferon-dependent signaling pathway with delayed kinetics, which amplifies and stabilizes the antiviral response. May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis. Involved in NLRP3 inflammasome activation by mediating NLRP3 recruitment to mitochondria., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0035591 signaling adaptor activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005777 peroxisome", "go_biological_process": "GO:0032727 positive regulation of interferon-alpha production;GO:0070585 protein localization to mitochondrion;GO:1900063 regulation of peroxisome organization;GO:0045087 innate immune response;GO:0051607 defense response to virus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G5L5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G5N9-1", "uniprot_id": [ { "id": "A0A9J7G5N9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G5N9", "type": "external" } ], "mass": 66562.0, "length": 608, "protein_name": "Serine/threonine-protein kinase 35", "gene_name": "Stk35", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: serine/threonine-protein kinase 35 isoform X2", "refseq_ac": [ { "id": "XP_027277621", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277621", "type": "external" } ], "gene_names_uniprotkb": "Stk35", "gene_names_refseq": "Stk35", "protein_names_uniprotkb": "Serine/threonine-protein kinase 35; 2.7.11.1; Serine/threonine-protein kinase 35 L1", "protein_names_refseq": "LOW QUALITY PROTEIN: serine/threonine-protein kinase 35 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100750596)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm", "go_biological_process": "GO:0110031 negative regulation of G2/MI transition of meiotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G5N9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G5T4-1", "uniprot_id": [ { "id": "A0A9J7G5T4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G5T4", "type": "external" } ], "mass": 45241.0, "length": 411, "protein_name": "Inhibin beta B chain", "gene_name": "Inhbb", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: inhibin beta B chain isoform X2", "refseq_ac": [ { "id": "XP_027273615", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273615", "type": "external" } ], "gene_names_uniprotkb": "Inhbb", "gene_names_refseq": "Inhbb", "protein_names_uniprotkb": "Inhibin beta B chain; Activin beta-B chain", "protein_names_refseq": "LOW QUALITY PROTEIN: inhibin beta B chain isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100759312)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 2 indels ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Activin B is a dimer of alpha and beta-B that plays a role in several essential biological processes including embryonic development, stem cell maintenance and differentiation, haematopoiesis, cell proliferation and wound healing. Signals through type I receptor ACVR1C, abundantly expressed in pancreatic beta cells, and type II receptors like ACVR2A. Upon ligand binding, these receptors phosphorylate intracellular signaling mediators SMAD2 and SMAD3, which form a complex with SMAD4, translocate to the nucleus, and regulate gene expression. Plays a crucial role in the induction of hepcidin by inflammation through activation of ACVR1C and subsequent phosphorylation of SMAD1/5/8. Regulates adipocyte lipid metabolism by decreasing non-esterified fatty acids and glycerol release and increases intracellular triglyceride content. Stimulates wound healing by promoting cell migration and hair follicle regeneration through the JNK and ERK signaling pathways downstream of RHOA., [UniProtKB, UniProtKB]; Inhibin B is a dimer of alpha and beta-B that plays a crucial role in the regulation of the reproductive system by inhibiting the secretion of follicle-stimulating hormone (FSH) from the anterior pituitary gland. Thereby, maintains reproductive homeostasis in both males and females. Acts as a more potent suppressor of FSH release than inhibin A. Functions as competitive receptor antagonist binding activin type II receptors with high affinity in the presence of the TGF-beta type III coreceptor/TGFBR3L., [UniProtKB, UniProtKB]; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005125 cytokine activity;GO:0005179 hormone activity;GO:0008083 growth factor activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G5T4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G5W9-1", "uniprot_id": [ { "id": "A0A9J7G5W9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G5W9", "type": "external" } ], "mass": 80750.0, "length": 752, "protein_name": "ATPase family gene 2 protein homolog B", "gene_name": "Spata5l1", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: spermatogenesis-associated protein 5-like protein 1 isoform X2", "refseq_ac": [ { "id": "XP_027277787", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277787", "type": "external" } ], "gene_names_uniprotkb": "Spata5l1", "gene_names_refseq": "Spata5l1", "protein_names_uniprotkb": "ATPase family gene 2 protein homolog B; 3.6.4.10; AFG2 AAA ATPase homolog B; Ribosome biogenesis protein SPATA5L1; Spermatogenesis-associated protein 5-like protein 1", "protein_names_refseq": "LOW QUALITY PROTEIN: spermatogenesis-associated protein 5-like protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100773232)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; ATP-dependent chaperone part of the 55LCC heterohexameric ATPase complex which is chromatin-associated and promotes replisome proteostasis to maintain replication fork progression and genome stability. Required for replication fork progression, sister chromatid cohesion, and chromosome stability. The ATPase activity is specifically enhanced by replication fork DNA and is coupled to cysteine protease-dependent cleavage of replisome substrates in response to replication fork damage. Uses ATPase activity to process replisome substrates in S-phase, facilitating their proteolytic turnover from chromatin to ensure DNA replication and mitotic fidelity. Plays an essential role in the cytoplasmic maturation steps of pre-60S ribosomal particles by promoting the release of shuttling protein RSL24D1/RLP24 from the pre-ribosomal particles., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0031593 polyubiquitin modification-dependent protein binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex;GO:0005634 nucleus;GO:0005819 spindle;GO:0005829 cytosol", "go_biological_process": "GO:0097352 autophagosome maturation;GO:0042254 ribosome biogenesis;GO:0051228 mitotic spindle disassembly;GO:0030970 retrograde protein transport, ER to cytosol", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G5W9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G6N1-1", "uniprot_id": [ { "id": "A0A9J7G6N1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G6N1", "type": "external" } ], "mass": 511496.0, "length": 4657, "protein_name": "StAR-related lipid transfer protein 9", "gene_name": "Stard9", "organism": "Hamster", "refseq_name": "stAR-related lipid transfer protein 9 isoform X1", "refseq_ac": [ { "id": "XP_007620069", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007620069", "type": "external" } ], "gene_names_uniprotkb": "Stard9", "gene_names_refseq": "Stard9", "protein_names_uniprotkb": "StAR-related lipid transfer protein 9; START domain-containing protein 9", "protein_names_refseq": "stAR-related lipid transfer protein 9 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100769740)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613677.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Microtubule-dependent motor protein required for spindle pole assembly during mitosis. Required to stabilize the pericentriolar material (PCM)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0008289 lipid binding;GO:0003777 microtubule motor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005814 centriole", "go_biological_process": "GO:0051225 spindle assembly;GO:0007018 microtubule-based movement", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G6N1-1", "record_type": "protein", "filter_code": "0000000.0000101.000100.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G654-1", "uniprot_id": [ { "id": "A0A9J7G654_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G654", "type": "external" } ], "mass": 95406.0, "length": 889, "protein_name": "Tyrosine-protein kinase receptor", "gene_name": "Ltk", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: leukocyte tyrosine kinase receptor isoform X2", "refseq_ac": [ { "id": "XP_027277954", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277954", "type": "external" } ], "gene_names_uniprotkb": "Ltk", "gene_names_refseq": "Ltk", "protein_names_uniprotkb": "Tyrosine-protein kinase receptor; 2.7.10.1", "protein_names_refseq": "LOW QUALITY PROTEIN: leukocyte tyrosine kinase receptor isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772620)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0042127 regulation of cell population proliferation;GO:0045664 regulation of neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G654-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GAP2-1", "uniprot_id": [ { "id": "A0A9J7GAP2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GAP2", "type": "external" } ], "mass": 67580.0, "length": 602, "protein_name": "Mitochondrial tRNA methylthiotransferase CDK5RAP1", "gene_name": "Cdk5rap1", "organism": "Hamster", "refseq_name": "mitochondrial tRNA methylthiotransferase CDK5RAP1 isoform X1", "refseq_ac": [ { "id": "XP_027277240", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277240", "type": "external" } ], "gene_names_uniprotkb": "Cdk5rap1", "gene_names_refseq": "Cdk5rap1", "protein_names_uniprotkb": "Mitochondrial tRNA methylthiotransferase CDK5RAP1; 2.8.4.3; CDK5 activator-binding protein C42; CDK5 regulatory subunit-associated protein 1; mt-tRNA-2-methylthio-N6-dimethylallyladenosine synthase; mt-tRNA-N6-(dimethylallyl)adenosine(37) methylthiotransferase", "protein_names_refseq": "mitochondrial tRNA methylthiotransferase CDK5RAP1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100773409)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Methylthiotransferase that catalyzes the conversion of N6-(dimethylallyl)adenosine (i(6)A) to 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 (adjacent to the 3'-end of the anticodon) of four mitochondrial DNA-encoded tRNAs (Ser(UCN), Phe, Tyr and Trp). Essential for efficient and highly accurate protein translation by the ribosome. Specifically inhibits CDK5 activation by CDK5R1. Essential for efficient mitochondrial protein synthesis and respiratory chain., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.8.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.4.3", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0035597 tRNA-2-methylthio-N(6)-dimethylallyladenosine(37) synthase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0051246 regulation of protein metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GAP2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G6B9-1", "uniprot_id": [ { "id": "A0A9J7G6B9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G6B9", "type": "external" } ], "mass": 36369.0, "length": 324, "protein_name": "Secreted frizzled-related protein 3", "gene_name": "Frzb", "organism": "Hamster", "refseq_name": "secreted frizzled-related protein 3", "refseq_ac": [ { "id": "XP_027275872", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275872", "type": "external" } ], "gene_names_uniprotkb": "Frzb", "gene_names_refseq": "Frzb", "protein_names_uniprotkb": "Secreted frizzled-related protein 3; Frizzled-related protein 1; FrzB-1", "protein_names_refseq": "secreted frizzled-related protein 3", "tax_id": 10029, "disease": "", "pathway": " (cge:100757779)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017147 Wnt-protein binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm", "go_biological_process": "GO:0048731 system development;GO:0030154 cell differentiation;GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0045595 regulation of cell differentiation;GO:0060070 canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G6B9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G6X0-1", "uniprot_id": [ { "id": "A0A9J7G6X0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G6X0", "type": "external" } ], "mass": 40414.0, "length": 361, "protein_name": "Brain-derived neurotrophic factor", "gene_name": "LOC113836414", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: brain-derived neurotrophic factor-like", "refseq_ac": [ { "id": "XP_027278097", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278097", "type": "external" } ], "gene_names_uniprotkb": "LOC113836414", "gene_names_refseq": "LOC113836414", "protein_names_uniprotkb": "Brain-derived neurotrophic factor; proBDNF", "protein_names_refseq": "LOW QUALITY PROTEIN: brain-derived neurotrophic factor-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113836414)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## internal stop codons :: corrected 2 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS., [UniProtKB, UniProtKB]; Important signaling molecule that activates signaling cascades downstream of NTRK2. Activates signaling cascades via the heterodimeric receptor formed by NGFR and SORCS2. Signaling via NGFR and SORCS2 plays a role in synaptic plasticity and long-term depression (LTD). Binding to NGFR and SORCS2 promotes neuronal apoptosis. Promotes neuronal growth cone collapse., [UniProtKB, UniProtKB]; Important signaling molecule that activates signaling cascades downstream of NTRK2. During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008083 growth factor activity;GO:0005163 nerve growth factor receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0030424 axon;GO:0030425 dendrite;GO:0008021 synaptic vesicle", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0048812 neuron projection morphogenesis;GO:0043524 negative regulation of neuron apoptotic process;GO:0050804 modulation of chemical synaptic transmission;GO:0021675 nerve development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G6X0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G7U0-1", "uniprot_id": [ { "id": "A0A9J7G7U0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G7U0", "type": "external" } ], "mass": 151253.0, "length": 1357, "protein_name": "lysophospholipase", "gene_name": "Pnpla7", "organism": "Hamster", "refseq_name": "patatin-like phospholipase domain-containing protein 7 isoform X1", "refseq_ac": [ { "id": "XP_016835227", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016835227", "type": "external" } ], "gene_names_uniprotkb": "Pnpla7", "gene_names_refseq": "Pnpla7", "protein_names_uniprotkb": "lysophospholipase; 3.1.1.5", "protein_names_refseq": "patatin-like phospholipase domain-containing protein 7 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100753361)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614905.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "3.1.2.22", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.22", "type": "external" }, { "id": "3.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.-", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "3.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004622 phosphatidylcholine lysophospholipase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0016042 lipid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G7U0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GAF2-1", "uniprot_id": [ { "id": "A0A9J7GAF2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GAF2", "type": "external" } ], "mass": 66664.0, "length": 575, "protein_name": "Cation channel sperm-associated protein 2", "gene_name": "Catsper2", "organism": "Hamster", "refseq_name": "cation channel sperm-associated protein 2 isoform X1", "refseq_ac": [ { "id": "XP_007619711", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007619711", "type": "external" } ], "gene_names_uniprotkb": "Catsper2", "gene_names_refseq": "Catsper2", "protein_names_uniprotkb": "Cation channel sperm-associated protein 2", "protein_names_refseq": "cation channel sperm-associated protein 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100766859)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613677.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Pore-forming subunit of the CatSper complex, a sperm-specific voltage-gated calcium channel that plays a central role in sperm cell hyperactivation. Controls calcium entry to mediate the hyperactivated motility, a step needed for sperm motility which is essential late in the preparation of sperm for fertilization., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0005227 calcium-activated cation channel activity;GO:0005245 voltage-gated calcium channel activity", "go_cellular_component": "GO:0036128 CatSper complex", "go_biological_process": "GO:0009566 fertilization;GO:0030317 flagellated sperm motility;GO:0048240 sperm capacitation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GAF2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G7L1-1", "uniprot_id": [ { "id": "A0A9J7G7L1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G7L1", "type": "external" } ], "mass": 149504.0, "length": 1354, "protein_name": "Receptor-type tyrosine-protein phosphatase eta", "gene_name": "Ptprj", "organism": "Hamster", "refseq_name": "receptor-type tyrosine-protein phosphatase eta isoform X3", "refseq_ac": [ { "id": "XP_027278416", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278416", "type": "external" } ], "gene_names_uniprotkb": "Ptprj", "gene_names_refseq": "Ptprj", "protein_names_uniprotkb": "Receptor-type tyrosine-protein phosphatase eta; 3.1.3.48; Protein-tyrosine phosphatase receptor type J", "protein_names_refseq": "receptor-type tyrosine-protein phosphatase eta isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100765394)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" } ], "go_molecular_function": "GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0043235 receptor complex;GO:0032587 ruffle membrane;GO:0070161 anchoring junction", "go_biological_process": "GO:0032502 developmental process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G7L1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G7A2-1", "uniprot_id": [ { "id": "A0A9J7G7A2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G7A2", "type": "external" } ], "mass": 30126.0, "length": 265, "protein_name": "Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial", "gene_name": "Coq4", "organism": "Hamster", "refseq_name": "ubiquinone biosynthesis protein COQ4 homolog, mitochondrial", "refseq_ac": [ { "id": "XP_003511843", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511843", "type": "external" } ], "gene_names_uniprotkb": "Coq4; COQ4", "gene_names_refseq": "Coq4", "protein_names_uniprotkb": "Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; 4-hydroxy-3-methoxy-5-polyprenylbenzoate decarboxylase; 4.1.1.130; Coenzyme Q biosynthesis protein 4 homolog", "protein_names_refseq": "ubiquinone biosynthesis protein COQ4 homolog, mitochondrial", "tax_id": 10029, "disease": "", "pathway": " (cge:100766160)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615231.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Lyase that catalyzes the C1-decarboxylation of 4-hydroxy-3-methoxy-5-(all-trans-decaprenyl)benzoic acid into 2-methoxy-6-(all-trans-decaprenyl)phenol during ubiquinone biosynthesis., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.1.1.130", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.130", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0120539 4-hydroxy-3-methoxy-5-polyprenylbenzoate decarboxylase activity", "go_cellular_component": "GO:0031314 extrinsic component of mitochondrial inner membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G7A2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G9D1-1", "uniprot_id": [ { "id": "A0A9J7G9D1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G9D1", "type": "external" } ], "mass": 135178.0, "length": 1230, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Hipk3", "organism": "Hamster", "refseq_name": "homeodomain-interacting protein kinase 3 isoform X1", "refseq_ac": [ { "id": "XP_027278139", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278139", "type": "external" } ], "gene_names_uniprotkb": "Hipk3", "gene_names_refseq": "Hipk3", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "homeodomain-interacting protein kinase 3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100772418)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016605 PML body", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G9D1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G7K2-1", "uniprot_id": [ { "id": "A0A9J7G7K2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G7K2", "type": "external" } ], "mass": 50616.0, "length": 439, "protein_name": "Tyrosine-protein phosphatase non-receptor type", "gene_name": "Ptpn1", "organism": "Hamster", "refseq_name": "tyrosine-protein phosphatase non-receptor type 1 isoform X3", "refseq_ac": [ { "id": "XP_027279141", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279141", "type": "external" } ], "gene_names_uniprotkb": "Ptpn1", "gene_names_refseq": "Ptpn1", "protein_names_uniprotkb": "Tyrosine-protein phosphatase non-receptor type; 3.1.3.48", "protein_names_refseq": "tyrosine-protein phosphatase non-receptor type 1 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100761071)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" } ], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0004726 non-membrane spanning protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005769 early endosome;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0070373 negative regulation of ERK1 and ERK2 cascade;GO:1903898 negative regulation of PERK-mediated unfolded protein response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G7K2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G7V4-1", "uniprot_id": [ { "id": "A0A9J7G7V4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G7V4", "type": "external" } ], "mass": 31209.0, "length": 284, "protein_name": "Plasma membrane ascorbate-dependent reductase CYBRD1", "gene_name": "LOC100767807", "organism": "Hamster", "refseq_name": "cytochrome b reductase 1 isoform X1", "refseq_ac": [ { "id": "XP_027276006", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276006", "type": "external" } ], "gene_names_uniprotkb": "LOC100767807", "gene_names_refseq": "LOC100767807", "protein_names_uniprotkb": "Plasma membrane ascorbate-dependent reductase CYBRD1; 7.2.1.3; Cytochrome b reductase 1", "protein_names_refseq": "cytochrome b reductase 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100767807)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "7.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.1.3", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0140571 transmembrane ascorbate ferrireductase activity", "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0016324 apical plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G7V4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G9Y7-1", "uniprot_id": [ { "id": "A0A9J7G9Y7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G9Y7", "type": "external" } ], "mass": 95445.0, "length": 840, "protein_name": "Anaphase-promoting complex subunit 2", "gene_name": "Anapc2", "organism": "Hamster", "refseq_name": "anaphase-promoting complex subunit 2 isoform X2", "refseq_ac": [ { "id": "XP_027278652", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278652", "type": "external" } ], "gene_names_uniprotkb": "Anapc2", "gene_names_refseq": "Anapc2", "protein_names_uniprotkb": "Anaphase-promoting complex subunit 2; Cyclosome subunit 2", "protein_names_refseq": "anaphase-promoting complex subunit 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774636)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Together with the RING-H2 protein ANAPC11, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 drives presynaptic differentiation., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005680 anaphase-promoting complex", "go_biological_process": "GO:0070979 protein K11-linked ubiquitination;GO:0007091 metaphase/anaphase transition of mitotic cell cycle;GO:0007399 nervous system development;GO:0030154 cell differentiation;GO:0051301 cell division", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G9Y7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G7W7-1", "uniprot_id": [ { "id": "A0A9J7G7W7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G7W7", "type": "external" } ], "mass": 74848.0, "length": 656, "protein_name": "alpha-1,2-Mannosidase", "gene_name": "LOC100756512", "organism": "Hamster", "refseq_name": "endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase isoform X1", "refseq_ac": [ { "id": "XP_016819544", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016819544", "type": "external" } ], "gene_names_uniprotkb": "LOC100756512", "gene_names_refseq": "LOC100756512", "protein_names_uniprotkb": "alpha-1,2-Mannosidase; 3.2.1.-", "protein_names_refseq": "endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100756512)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 611 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003619160.1) and transcript sequence (JI862143.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1,2-linked mannose residue from Man(9)GlcNAc(2) to produce Man(8)GlcNAc(2), but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man(5-6)GlcNAc(2)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.2.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.-", "type": "external" } ], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0036503 ERAD pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G7W7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G7W8-1", "uniprot_id": [ { "id": "A0A9J7G7W8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G7W8", "type": "external" } ], "mass": 53399.0, "length": 481, "protein_name": "Lipopolysaccharide-binding protein", "gene_name": "Lbp", "organism": "Hamster", "refseq_name": "lipopolysaccharide-binding protein", "refseq_ac": [ { "id": "XP_027277049", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277049", "type": "external" } ], "gene_names_uniprotkb": "Lbp", "gene_names_refseq": "Lbp", "protein_names_uniprotkb": "Lipopolysaccharide-binding protein; LBP", "protein_names_refseq": "lipopolysaccharide-binding protein", "tax_id": 10029, "disease": "", "pathway": " (cge:100759867)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001530 lipopolysaccharide binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0043032 positive regulation of macrophage activation;GO:0006869 lipid transport;GO:0045087 innate immune response;GO:0050829 defense response to Gram-negative bacterium;GO:0050830 defense response to Gram-positive bacterium", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G7W8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G7Y2-1", "uniprot_id": [ { "id": "A0A9J7G7Y2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G7Y2", "type": "external" } ], "mass": 12313.0, "length": 107, "protein_name": "Somatoliberin", "gene_name": "Ghrh", "organism": "Hamster", "refseq_name": "somatoliberin isoform X1", "refseq_ac": [ { "id": "XP_027277075", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277075", "type": "external" } ], "gene_names_uniprotkb": "Ghrh", "gene_names_refseq": "Ghrh", "protein_names_uniprotkb": "Somatoliberin; Growth hormone-releasing factor; Growth hormone-releasing hormone", "protein_names_refseq": "somatoliberin isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100756401)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; GRF is released by the hypothalamus and acts on the adenohypophyse to stimulate the secretion of growth hormone., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031770 growth hormone-releasing hormone receptor binding;GO:0005184 neuropeptide hormone activity;GO:0051428 peptide hormone receptor binding;GO:0016608 growth hormone-releasing hormone activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0043195 terminal bouton;GO:0043204 perikaryon", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0032880 regulation of protein localization;GO:0030252 growth hormone secretion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G7Y2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G7Z7-1", "uniprot_id": [ { "id": "A0A9J7G7Z7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G7Z7", "type": "external" } ], "mass": 114966.0, "length": 1061, "protein_name": "Glutamate receptor", "gene_name": "Grin3b", "organism": "Hamster", "refseq_name": "glutamate receptor ionotropic, NMDA 3B isoform X2", "refseq_ac": [ { "id": "XP_027275245", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275245", "type": "external" } ], "gene_names_uniprotkb": "Grin3b", "gene_names_refseq": "Grin3b", "protein_names_uniprotkb": "Glutamate receptor", "protein_names_refseq": "glutamate receptor ionotropic, NMDA 3B isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100753630)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027275245.1. COMPLETENESS: full length., [RefSeq]; Component of a non-conventional N-methyl-D-aspartate (NMDA) receptors (NMDARs) that function as heterotetrameric, ligand-gated cation channels with low calcium permeability and low voltage-dependent block by Mg(2+). Forms glutamatergic receptor complexes with GluN1 and GluN2 subunits which are activated by glycine binding to the GluN1 and GluN3 subunits and L-glutamate binding to GluN2 subunits. Forms excitatory glycinergic receptor complexes with GluN1 alone which are activated by glycine binding to the GluN1 and GluN3 subunits. GluN3B subunit also binds D-serine and, in the absence of glycine, activates glycinergic receptor complexes, but with lower efficacy than glycine. Each GluN3 subunit confers differential attributes to channel properties, including activation, deactivation and desensitization kinetics, pH sensitivity, Ca2(+) permeability, and binding to allosteric modulators., [UniProtKB, UniProtKB]; Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0017146 NMDA selective glutamate receptor complex;GO:0045211 postsynaptic membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G7Z7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G855-1", "uniprot_id": [ { "id": "A0A9J7G855_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G855", "type": "external" } ], "mass": 49764.0, "length": 443, "protein_name": "Activin receptor type-1C", "gene_name": "Acvr1c", "organism": "Hamster", "refseq_name": "activin receptor type-1C isoform X1", "refseq_ac": [ { "id": "XP_007642197", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642197", "type": "external" } ], "gene_names_uniprotkb": "Acvr1c", "gene_names_refseq": "Acvr1c", "protein_names_uniprotkb": "Activin receptor type-1C; 2.7.11.30; Activin receptor type IC; Activin receptor-like kinase 7", "protein_names_refseq": "activin receptor type-1C isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100756930)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613966.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consists of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B, activin E and NODAL. Upon NODAL binding, activation results in increased apoptosis and reduced proliferation through suppression of AKT signaling and the activation of Smad2-dependent signaling pathway in pancreatic beta-cells, trophoblasts, epithelial or neuronal cells. Acts as a positive regulator for macrophage activation partially through down-regulation of PPARG expression., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.30", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.30", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004675 transmembrane receptor protein serine/threonine kinase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0006915 apoptotic process;GO:0071363 cellular response to growth factor stimulus;GO:0009749 response to glucose", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G855-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G864-1", "uniprot_id": [ { "id": "A0A9J7G864_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G864", "type": "external" } ], "mass": 84111.0, "length": 727, "protein_name": "E3 ubiquitin-protein ligase LRSAM1", "gene_name": "Lrsam1", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase LRSAM1", "refseq_ac": [ { "id": "XP_027279573", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279573", "type": "external" } ], "gene_names_uniprotkb": "Lrsam1", "gene_names_refseq": "Lrsam1", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase LRSAM1; 2.3.2.27; Leucine-rich repeat and sterile alpha motif-containing protein 1; RING-type E3 ubiquitin transferase LRSAM1; Tsg101-associated ligase", "protein_names_refseq": "E3 ubiquitin-protein ligase LRSAM1", "tax_id": 10029, "disease": "", "pathway": " (cge:100758009)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0015031 protein transport;GO:0006914 autophagy", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G864-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G884-1", "uniprot_id": [ { "id": "A0A9J7G884_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G884", "type": "external" } ], "mass": 21479.0, "length": 191, "protein_name": "Prostaglandin-H2 D-isomerase", "gene_name": "Ptgds", "organism": "Hamster", "refseq_name": "prostaglandin-H2 D-isomerase", "refseq_ac": [ { "id": "XP_003515537", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003515537", "type": "external" } ], "gene_names_uniprotkb": "Ptgds", "gene_names_refseq": "Ptgds", "protein_names_uniprotkb": "Prostaglandin-H2 D-isomerase; 5.3.99.2; Glutathione-independent PGD synthase; Lipocalin-type prostaglandin-D synthase; Prostaglandin-D2 synthase", "protein_names_refseq": "prostaglandin-H2 D-isomerase", "tax_id": 10029, "disease": "", "pathway": " (cge:100762704)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003618227.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.3.99.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.99.2", "type": "external" }, { "id": "2.5.1.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.18", "type": "external" } ], "go_molecular_function": "GO:0004667 prostaglandin-D synthase activity;GO:0036094 small molecule binding;GO:0005501 retinoid binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005791 rough endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0031965 nuclear membrane;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0001516 prostaglandin biosynthetic process;GO:0043303 mast cell degranulation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G884-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G9E3-1", "uniprot_id": [ { "id": "A0A9J7G9E3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G9E3", "type": "external" } ], "mass": 63511.0, "length": 579, "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "Mgrn1", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase MGRN1 isoform X1", "refseq_ac": [ { "id": "XP_027279781", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279781", "type": "external" } ], "gene_names_uniprotkb": "Mgrn1", "gene_names_refseq": "Mgrn1", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase; 2.3.2.27; RING-type E3 ubiquitin transferase", "protein_names_refseq": "E3 ubiquitin-protein ligase MGRN1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100772863)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; E3 ubiquitin ligase., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005769 early endosome;GO:0005886 plasma membrane", "go_biological_process": "GO:0045744 negative regulation of G protein-coupled receptor signaling pathway;GO:0008333 endosome to lysosome transport;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G9E3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G8M6-1", "uniprot_id": [ { "id": "A0A9J7G8M6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G8M6", "type": "external" } ], "mass": 75965.0, "length": 701, "protein_name": "Protein CASC3", "gene_name": "Casc3", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: protein CASC3 isoform X2", "refseq_ac": [ { "id": "XP_027279916", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279916", "type": "external" } ], "gene_names_uniprotkb": "Casc3", "gene_names_refseq": "Casc3", "protein_names_uniprotkb": "Protein CASC3", "protein_names_refseq": "LOW QUALITY PROTEIN: protein CASC3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100773741)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0016607 nuclear speck;GO:0030425 dendrite;GO:0048471 perinuclear region of cytoplasm;GO:0005681 spliceosomal complex;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0006397 mRNA processing;GO:0006417 regulation of translation;GO:0008380 RNA splicing;GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0051028 mRNA transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G8M6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G8R4-1", "uniprot_id": [ { "id": "A0A9J7G8R4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G8R4", "type": "external" } ], "mass": 47873.0, "length": 437, "protein_name": "Metalloendopeptidase", "gene_name": "Astl", "organism": "Hamster", "refseq_name": "astacin-like metalloendopeptidase", "refseq_ac": [ { "id": "XP_027277702", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277702", "type": "external" } ], "gene_names_uniprotkb": "Astl", "gene_names_refseq": "Astl", "protein_names_uniprotkb": "Metalloendopeptidase; 3.4.24.-", "protein_names_refseq": "astacin-like metalloendopeptidase", "tax_id": 10029, "disease": "", "pathway": " (cge:100750643)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0060473 cortical granule", "go_biological_process": "GO:0006508 proteolysis;GO:0007338 single fertilization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G8R4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G8U8-1", "uniprot_id": [ { "id": "A0A9J7G8U8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G8U8", "type": "external" } ], "mass": 55373.0, "length": 503, "protein_name": "Sodium/potassium/calcium exchanger 5", "gene_name": "Slc24a5", "organism": "Hamster", "refseq_name": "sodium/potassium/calcium exchanger 5", "refseq_ac": [ { "id": "XP_003506297", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506297", "type": "external" } ], "gene_names_uniprotkb": "Slc24a5", "gene_names_refseq": "Slc24a5", "protein_names_uniprotkb": "Sodium/potassium/calcium exchanger 5; Na(+)/K(+)/Ca(2+)-exchange protein 5; Solute carrier family 24 member 5", "protein_names_refseq": "sodium/potassium/calcium exchanger 5", "tax_id": 10029, "disease": "", "pathway": " (cge:100762640)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614219.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Dec 18, 2018 this sequence version replaced XP_003506297.2. COMPLETENESS: full length., [RefSeq]; Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) to the melanosome in exchange for 4 cytoplasmic Na(+). Involved in pigmentation, possibly by participating in ion transport in melanosomes. Predominant sodium-calcium exchanger in melanocytes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005262 calcium channel activity;GO:0015293 symporter activity;GO:0008273 calcium, potassium:sodium antiporter activity", "go_cellular_component": "GO:0016020 membrane;GO:0042470 melanosome;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0006874 intracellular calcium ion homeostasis;GO:0070509 calcium ion import;GO:0030318 melanocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G8U8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G8W2-1", "uniprot_id": [ { "id": "A0A9J7G8W2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G8W2", "type": "external" } ], "mass": 175007.0, "length": 1545, "protein_name": "NAD(P)H oxidase (H2O2-forming)", "gene_name": "Duox2", "organism": "Hamster", "refseq_name": "dual oxidase 2 isoform X2", "refseq_ac": [ { "id": "XP_027277795", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277795", "type": "external" } ], "gene_names_uniprotkb": "Duox2", "gene_names_refseq": "Duox2", "protein_names_uniprotkb": "NAD(P)H oxidase (H2O2-forming); 1.6.3.1", "protein_names_refseq": "dual oxidase 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100764526)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.6.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.3.1", "type": "external" }, { "id": "1.6.99.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.99.1", "type": "external" }, { "id": "1.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.-.-.-", "type": "external" }, { "id": "1.14.13.225", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.225", "type": "external" }, { "id": "1.14.13.8", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.8", "type": "external" } ], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0020037 heme binding;GO:0016174 NAD(P)H oxidase H2O2-forming activity;GO:0004601 peroxidase activity;GO:0016175 superoxide-generating NAD(P)H oxidase activity", "go_cellular_component": "GO:0043020 NADPH oxidase complex;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0006952 defense response;GO:0006979 response to oxidative stress;GO:0042446 hormone biosynthetic process;GO:0042744 hydrogen peroxide catabolic process;GO:0006590 thyroid hormone generation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G8W2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G912-1", "uniprot_id": [ { "id": "A0A9J7G912_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G912", "type": "external" } ], "mass": 75209.0, "length": 685, "protein_name": "tRNA wybutosine-synthesizing protein 4", "gene_name": "Lcmt2", "organism": "Hamster", "refseq_name": "tRNA wybutosine-synthesizing protein 4 isoform X2", "refseq_ac": [ { "id": "XP_027277876", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277876", "type": "external" } ], "gene_names_uniprotkb": "Lcmt2", "gene_names_refseq": "Lcmt2", "protein_names_uniprotkb": "tRNA wybutosine-synthesizing protein 4; 2.1.1.290; 2.3.1.231; Leucine carboxyl methyltransferase 2; tRNA(Phe) (7-(3-amino-3-(methoxycarbonyl)propyl)wyosine(37)-N)-methoxycarbonyltransferase; tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase", "protein_names_refseq": "tRNA wybutosine-synthesizing protein 4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100768317)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. May methylate the carboxyl group of leucine residues to form alpha-leucine ester residues., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.290", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.290", "type": "external" }, { "id": "2.3.1.231", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.231", "type": "external" } ], "go_molecular_function": "GO:0008175 tRNA methyltransferase activity", "go_cellular_component": "", "go_biological_process": "GO:0030488 tRNA methylation;GO:0031591 wybutosine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G912-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G966-1", "uniprot_id": [ { "id": "A0A9J7G966_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G966", "type": "external" } ], "mass": 133528.0, "length": 1171, "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase", "gene_name": "Plcb2", "organism": "Hamster", "refseq_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2", "refseq_ac": [ { "id": "XP_003512647", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512647", "type": "external" } ], "gene_names_uniprotkb": "Plcb2", "gene_names_refseq": "Plcb2", "protein_names_uniprotkb": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; 3.1.4.11", "protein_names_refseq": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2", "tax_id": 10029, "disease": "", "pathway": " (cge:100760731)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615510.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In neutrophils, participates in a phospholipase C-activating N-formyl peptide-activated GPCR (G protein-coupled receptor) signaling pathway by promoting RASGRP4 activation by DAG, to promote neutrophil functional responses., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.4.11", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.11", "type": "external" } ], "go_molecular_function": "GO:0004435 phosphatidylinositol-4,5-bisphosphate phospholipase C activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0016042 lipid catabolic process;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0051209 release of sequestered calcium ion into cytosol;GO:0048015 phosphatidylinositol-mediated signaling;GO:0046488 phosphatidylinositol metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G966-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G969-1", "uniprot_id": [ { "id": "A0A9J7G969_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G969", "type": "external" } ], "mass": 120709.0, "length": 1065, "protein_name": "Mitotic checkpoint serine/threonine-protein kinase BUB1 beta", "gene_name": "LOC100754771", "organism": "Hamster", "refseq_name": "mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform X4", "refseq_ac": [ { "id": "XP_027278005", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278005", "type": "external" } ], "gene_names_uniprotkb": "LOC100754771", "gene_names_refseq": "LOC100754771", "protein_names_uniprotkb": "Mitotic checkpoint serine/threonine-protein kinase BUB1 beta; 2.7.11.1; MAD3/BUB1-related protein kinase; Mitotic checkpoint kinase MAD3L", "protein_names_refseq": "mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100754771)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000940 outer kinetochore;GO:0005819 spindle;GO:0005829 cytosol", "go_biological_process": "GO:0051301 cell division;GO:0006915 apoptotic process;GO:0051754 meiotic sister chromatid cohesion, centromeric;GO:0007094 mitotic spindle assembly checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G969-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G9E2-1", "uniprot_id": [ { "id": "A0A9J7G9E2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G9E2", "type": "external" } ], "mass": 63129.0, "length": 555, "protein_name": "Catalase", "gene_name": "Cat", "organism": "Hamster", "refseq_name": "catalase isoform X1", "refseq_ac": [ { "id": "XP_027278163", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278163", "type": "external" } ], "gene_names_uniprotkb": "Cat", "gene_names_refseq": "Cat", "protein_names_uniprotkb": "Catalase; 1.11.1.6", "protein_names_refseq": "catalase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100773774)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.11.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.6", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0004096 catalase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005782 peroxisomal matrix", "go_biological_process": "GO:0042542 response to hydrogen peroxide;GO:0051781 positive regulation of cell division;GO:0042744 hydrogen peroxide catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G9E2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GDV9-1", "uniprot_id": [ { "id": "A0A9J7GDV9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GDV9", "type": "external" } ], "mass": 97767.0, "length": 868, "protein_name": "Dynamin-1", "gene_name": "Dnm1", "organism": "Hamster", "refseq_name": "dynamin-1 isoform X2", "refseq_ac": [ { "id": "XP_027279633", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279633", "type": "external" } ], "gene_names_uniprotkb": "Dnm1", "gene_names_refseq": "Dnm1", "protein_names_uniprotkb": "Dynamin-1; 3.6.5.5; Dynamin I", "protein_names_refseq": "dynamin-1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100753867)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0008017 microtubule binding", "go_cellular_component": "GO:0098835 presynaptic endocytic zone membrane;GO:0005874 microtubule;GO:0005905 clathrin-coated pit;GO:0042583 chromaffin granule", "go_biological_process": "GO:0031623 receptor internalization;GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GDV9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G9G7-1", "uniprot_id": [ { "id": "A0A9J7G9G7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G9G7", "type": "external" } ], "mass": 103456.0, "length": 918, "protein_name": "Aminopeptidase", "gene_name": "Npepps", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: puromycin-sensitive aminopeptidase isoform X2", "refseq_ac": [ { "id": "XP_027279974", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279974", "type": "external" } ], "gene_names_uniprotkb": "Npepps", "gene_names_refseq": "Npepps", "protein_names_uniprotkb": "Aminopeptidase; 3.4.11.-", "protein_names_refseq": "LOW QUALITY PROTEIN: puromycin-sensitive aminopeptidase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763186)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 2 indels ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042277 peptide binding;GO:0070006 metalloaminopeptidase activity;GO:0016285 alanyl aminopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0043171 peptide catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G9G7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GA13-1", "uniprot_id": [ { "id": "A0A9J7GA13_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GA13", "type": "external" } ], "mass": 71688.0, "length": 622, "protein_name": "Histone acetyltransferase", "gene_name": "Kat7", "organism": "Hamster", "refseq_name": "histone acetyltransferase KAT7 isoform X5", "refseq_ac": [ { "id": "XP_007642669", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642669", "type": "external" } ], "gene_names_uniprotkb": "Kat7", "gene_names_refseq": "Kat7", "protein_names_uniprotkb": "Histone acetyltransferase; 2.3.1.48", "protein_names_refseq": "histone acetyltransferase KAT7 isoform X5", "tax_id": 10029, "disease": "", "pathway": " (cge:100757223)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614015.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "2.3.1.259", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.259", "type": "external" } ], "go_molecular_function": "GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0003712 transcription coregulator activity;GO:0010485 histone H4 acetyltransferase activity;GO:0036408 histone H3K14 acetyltransferase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0000775 chromosome, centromeric region;GO:0036409 histone H3-K14 acetyltransferase complex", "go_biological_process": "GO:0006281 DNA repair;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006260 DNA replication;GO:0045815 transcription initiation-coupled chromatin remodeling;GO:1902035 positive regulation of hematopoietic stem cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GA13-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G9R3-1", "uniprot_id": [ { "id": "A0A9J7G9R3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G9R3", "type": "external" } ], "mass": 12956.0, "length": 116, "protein_name": "Methionine-R-sulfoxide reductase B1", "gene_name": "Msrb1", "organism": "Hamster", "refseq_name": "methionine-R-sulfoxide reductase B1", "refseq_ac": [ { "id": "XP_016830633", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016830633", "type": "external" } ], "gene_names_uniprotkb": "Msrb1", "gene_names_refseq": "Msrb1", "protein_names_uniprotkb": "Methionine-R-sulfoxide reductase B1; 1.8.4.12; 1.8.4.14; Selenoprotein X", "protein_names_refseq": "methionine-R-sulfoxide reductase B1", "tax_id": 10029, "disease": "", "pathway": " (cge:100753803)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613852.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Acts as a regulator of actin assembly by reducing methionine (R)-sulfoxide mediated by MICALs (MICAL1, MICAL2 or MICAL3) on actin, thereby promoting filament repolymerization. Plays a role in innate immunity by reducing oxidized actin, leading to actin repolymerization in macrophages., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.8.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.4.12", "type": "external" }, { "id": "1.8.4.14", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.4.14", "type": "external" } ], "go_molecular_function": "GO:0033743 peptide-methionine (R)-S-oxide reductase activity;GO:0033745 L-methionine-(R)-S-oxide reductase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005856 cytoskeleton", "go_biological_process": "GO:0045087 innate immune response;GO:0030091 protein repair", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G9R3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G9U4-1", "uniprot_id": [ { "id": "A0A9J7G9U4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G9U4", "type": "external" } ], "mass": 130185.0, "length": 1161, "protein_name": "BAI1-associated protein 3", "gene_name": "Baiap3", "organism": "Hamster", "refseq_name": "BAI1-associated protein 3", "refseq_ac": [ { "id": "XP_003501622", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501622", "type": "external" } ], "gene_names_uniprotkb": "Baiap3", "gene_names_refseq": "Baiap3", "protein_names_uniprotkb": "BAI1-associated protein 3; Brain-specific angiogenesis inhibitor I-associated protein 3", "protein_names_refseq": "BAI1-associated protein 3", "tax_id": 10029, "disease": "", "pathway": " (cge:100751355)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613852.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Dec 18, 2018 this sequence version replaced XP_003501622.1. COMPLETENESS: full length., [RefSeq]; Functions in endosome to Golgi retrograde transport. In response to calcium influx, may interact with SNARE fusion receptors and membrane phospholipids to mediate endosome fusion with the trans-Golgi network. By promoting the recycling of secretory vesicle transmembrane proteins, it indirectly controls dense-core secretory vesicle biogenesis, maturation and their ability to mediate the constitutive and regulated secretion of neurotransmitters and hormones. May regulate behavior and food intake by controlling calcium-stimulated exocytosis of neurotransmitters including NPY and serotonin and hormones like insulin. Proposed to play a role in hypothalamic neuronal firing by modulating gamma-aminobutyric acid (GABA)ergic inhibitory neurotransmission., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000149 SNARE binding", "go_cellular_component": "GO:0099503 secretory vesicle;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0032588 trans-Golgi network membrane;GO:0031902 late endosome membrane", "go_biological_process": "GO:0006887 exocytosis;GO:1905413 regulation of dense core granule exocytosis;GO:0001956 positive regulation of neurotransmitter secretion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G9U4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GBJ4-1", "uniprot_id": [ { "id": "A0A9J7GBJ4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GBJ4", "type": "external" } ], "mass": 271220.0, "length": 2435, "protein_name": "ATP-binding cassette sub-family A member 2", "gene_name": "Abca2", "organism": "Hamster", "refseq_name": "ATP-binding cassette sub-family A member 2 isoform X3", "refseq_ac": [ { "id": "XP_027278680", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278680", "type": "external" } ], "gene_names_uniprotkb": "Abca2", "gene_names_refseq": "Abca2", "protein_names_uniprotkb": "ATP-binding cassette sub-family A member 2; ATP-binding cassette transporter 2", "protein_names_refseq": "ATP-binding cassette sub-family A member 2 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100772799)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Probable lipid transporter that modulates cholesterol sequestration in the late endosome/lysosome by regulating the intracellular sphingolipid metabolism, in turn participates in cholesterol homeostasis. May alter the transbilayer distribution of ceramide in the intraluminal membrane lipid bilayer, favoring its retention in the outer leaflet that results in increased acid ceramidase activity in the late endosome/lysosome, facilitating ceramide deacylation to sphingosine leading to the sequestration of free cholesterol in lysosomes. In addition regulates amyloid-beta production either by activating a signaling pathway that regulates amyloid precursor protein transcription through the modulation of sphingolipid metabolism or through its role in gamma-secretase processing of APP. May play a role in myelin formation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005319 lipid transporter activity;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0140359 ABC-type transporter activity;GO:0099038 ceramide floppase activity", "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0010008 endosome membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0032289 central nervous system myelin formation;GO:0051247 positive regulation of protein metabolic process;GO:0032383 regulation of intracellular cholesterol transport;GO:0042632 cholesterol homeostasis;GO:0048545 response to steroid hormone", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GBJ4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GA34-1", "uniprot_id": [ { "id": "A0A9J7GA34_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GA34", "type": "external" } ], "mass": 84225.0, "length": 783, "protein_name": "Transcription factor E4F1", "gene_name": "LOC100769603", "organism": "Hamster", "refseq_name": "transcription factor E4F1 isoform X2", "refseq_ac": [ { "id": "XP_027280719", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280719", "type": "external" } ], "gene_names_uniprotkb": "LOC100769603", "gene_names_refseq": "LOC100769603", "protein_names_uniprotkb": "Transcription factor E4F1; 2.3.2.27; E4F transcription factor 1; Putative E3 ubiquitin-protein ligase E4F1; RING-type E3 ubiquitin transferase E4F1; Transcription factor E4F; p120E4F", "protein_names_refseq": "transcription factor E4F1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100769603)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May function as a transcriptional repressor. May also function as a ubiquitin ligase mediating ubiquitination of chromatin-associated TP53. Functions in cell survival and proliferation through control of the cell cycle. Functions in the p53 and pRB tumor suppressor pathways and regulates the cyclin CCNA2 transcription., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0051301 cell division;GO:0010564 regulation of cell cycle process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GA34-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GA98-1", "uniprot_id": [ { "id": "A0A9J7GA98_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GA98", "type": "external" } ], "mass": 62086.0, "length": 558, "protein_name": "Matrix metalloproteinase-25", "gene_name": "Mmp25", "organism": "Hamster", "refseq_name": "matrix metalloproteinase-25", "refseq_ac": [ { "id": "XP_027280664", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280664", "type": "external" } ], "gene_names_uniprotkb": "Mmp25", "gene_names_refseq": "Mmp25", "protein_names_uniprotkb": "Matrix metalloproteinase-25", "protein_names_refseq": "matrix metalloproteinase-25", "tax_id": 10029, "disease": "", "pathway": " (cge:100774116)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May activate progelatinase A., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0031012 extracellular matrix;GO:0098552 side of membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0030198 extracellular matrix organization;GO:0030574 collagen catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GA98-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GAB0-1", "uniprot_id": [ { "id": "A0A9J7GAB0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GAB0", "type": "external" } ], "mass": 101092.0, "length": 907, "protein_name": "Serine/threonine-protein kinase N3", "gene_name": "Pkn3", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase N3 isoform X1", "refseq_ac": [ { "id": "XP_027278939", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278939", "type": "external" } ], "gene_names_uniprotkb": "Pkn3", "gene_names_refseq": "Pkn3", "protein_names_uniprotkb": "Serine/threonine-protein kinase N3; 2.7.11.13; Protein kinase PKN-beta; Protein-kinase C-related kinase 3", "protein_names_refseq": "serine/threonine-protein kinase N3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100769931)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Contributes to invasiveness in malignant prostate cancer., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0031267 small GTPase binding;GO:0004697 diacylglycerol-dependent serine/threonine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0007165 signal transduction;GO:0010631 epithelial cell migration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GAB0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GAC5-1", "uniprot_id": [ { "id": "A0A9J7GAC5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GAC5", "type": "external" } ], "mass": 36078.0, "length": 323, "protein_name": "Deoxyribonuclease-1-like 2", "gene_name": "LOC100769895", "organism": "Hamster", "refseq_name": "deoxyribonuclease-1-like 2 isoform X6", "refseq_ac": [ { "id": "XP_027280726", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280726", "type": "external" } ], "gene_names_uniprotkb": "LOC100769895", "gene_names_refseq": "LOC100769895", "protein_names_uniprotkb": "Deoxyribonuclease-1-like 2; Deoxyribonuclease I-like 2", "protein_names_refseq": "deoxyribonuclease-1-like 2 isoform X6", "tax_id": 10029, "disease": "", "pathway": " (cge:100769895)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Divalent cation-dependent acid DNA endonuclease involved in the breakdown of the nucleus during corneocyte formation of epidermal keratinocytes. May play an immune role by eliminating harmful DNA released into the extracellular environment by damaged epidermal cells., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0004530 deoxyribonuclease I activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005634 nucleus", "go_biological_process": "GO:0006308 DNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GAC5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GAG0-1", "uniprot_id": [ { "id": "A0A9J7GAG0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GAG0", "type": "external" } ], "mass": 510736.0, "length": 4510, "protein_name": "Apolipoprotein B-100 isoform X2", "gene_name": "Apob", "organism": "Hamster", "refseq_name": "apolipoprotein B-100 isoform X2", "refseq_ac": [ { "id": "XP_027280403", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280403", "type": "external" } ], "gene_names_uniprotkb": "Apob", "gene_names_refseq": "Apob", "protein_names_uniprotkb": "Apolipoprotein B-100 isoform X2", "protein_names_refseq": "apolipoprotein B-100 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762698)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008201 heparin binding;GO:0050750 low-density lipoprotein particle receptor binding;GO:0120020 cholesterol transfer activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005811 lipid droplet;GO:0034361 very-low-density lipoprotein particle;GO:0034362 low-density lipoprotein particle;GO:0034359 mature chylomicron", "go_biological_process": "GO:0008203 cholesterol metabolic process;GO:0042953 lipoprotein transport;GO:0042632 cholesterol homeostasis;GO:0030301 cholesterol transport;GO:0006642 triglyceride mobilization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GAG0-1", "record_type": "protein", "filter_code": "0000000.0000101.000100.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GAJ0-1", "uniprot_id": [ { "id": "A0A9J7GAJ0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GAJ0", "type": "external" } ], "mass": 200385.0, "length": 1753, "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "Ubr1", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase UBR1 isoform X1", "refseq_ac": [ { "id": "XP_003498129", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498129", "type": "external" } ], "gene_names_uniprotkb": "Ubr1", "gene_names_refseq": "Ubr1", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase; 2.3.2.27", "protein_names_refseq": "E3 ubiquitin-protein ligase UBR1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100769170)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613677.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0000151 ubiquitin ligase complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GAJ0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GAJ5-1", "uniprot_id": [ { "id": "A0A9J7GAJ5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GAJ5", "type": "external" } ], "mass": 118643.0, "length": 1047, "protein_name": "Phospholipid-transporting ATPase", "gene_name": "LOC100773673", "organism": "Hamster", "refseq_name": "probable phospholipid-transporting ATPase IIA isoform X2", "refseq_ac": [ { "id": "XP_027279122", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279122", "type": "external" } ], "gene_names_uniprotkb": "LOC100773673", "gene_names_refseq": "LOC100773673", "protein_names_uniprotkb": "Phospholipid-transporting ATPase; 7.6.2.1", "protein_names_refseq": "probable phospholipid-transporting ATPase IIA isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100773673)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0140326 ATPase-coupled intramembrane lipid transporter activity", "go_cellular_component": "GO:0005768 endosome;GO:0005886 plasma membrane;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0006897 endocytosis;GO:0045332 phospholipid translocation;GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GAJ5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GAQ3-1", "uniprot_id": [ { "id": "A0A9J7GAQ3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GAQ3", "type": "external" } ], "mass": 32202.0, "length": 289, "protein_name": "Enoyl-CoA delta isomerase 1, mitochondrial", "gene_name": "LOC100773350", "organism": "Hamster", "refseq_name": "enoyl-CoA delta isomerase 1, mitochondrial isoform X2", "refseq_ac": [ { "id": "XP_027280718", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280718", "type": "external" } ], "gene_names_uniprotkb": "LOC100773350", "gene_names_refseq": "LOC100773350", "protein_names_uniprotkb": "Enoyl-CoA delta isomerase 1, mitochondrial; 3,2-trans-enoyl-CoA isomerase; 5.3.3.8; Delta(3),Delta(2)-enoyl-CoA isomerase; Dodecenoyl-CoA isomerase", "protein_names_refseq": "enoyl-CoA delta isomerase 1, mitochondrial isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100773350)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Key enzyme of fatty acid beta-oxidation. Able to isomerize both 3-cis (3Z) and 3-trans (3E) double bonds into the 2-trans (2E) form in a range of enoyl-CoA species, with a preference for (3Z)-enoyl-CoAs over (3E)-enoyl-CoAs. The catalytic efficiency of this enzyme is not affected by the fatty acyl chain length., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.35", "type": "external" }, { "id": "4.2.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.17", "type": "external" }, { "id": "5.3.3.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.8", "type": "external" } ], "go_molecular_function": "GO:0004165 delta(3)-delta(2)-enoyl-CoA isomerase activity", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006635 fatty acid beta-oxidation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GAQ3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GAS9-1", "uniprot_id": [ { "id": "A0A9J7GAS9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GAS9", "type": "external" } ], "mass": 75602.0, "length": 661, "protein_name": "Arginine--tRNA ligase, cytoplasmic", "gene_name": "Rars1", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Rars1", "gene_names_refseq": "", "protein_names_uniprotkb": "Arginine--tRNA ligase, cytoplasmic; 6.1.1.19; Arginyl-tRNA synthetase", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:100767723)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.1.1.19", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.19", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004814 arginine-tRNA ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0017101 aminoacyl-tRNA synthetase multienzyme complex", "go_biological_process": "GO:0006420 arginyl-tRNA aminoacylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GAS9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GAU1-1", "uniprot_id": [ { "id": "A0A9J7GAU1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GAU1", "type": "external" } ], "mass": 101437.0, "length": 888, "protein_name": "Kinesin-like protein", "gene_name": "Kif18a", "organism": "Hamster", "refseq_name": "kinesin-like protein KIF18A isoform X1", "refseq_ac": [ { "id": "XP_027278098", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278098", "type": "external" } ], "gene_names_uniprotkb": "Kif18a", "gene_names_refseq": "Kif18a", "protein_names_uniprotkb": "Kinesin-like protein", "protein_names_refseq": "kinesin-like protein KIF18A isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100770187)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0003777 microtubule motor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005819 spindle;GO:0005874 microtubule", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0007018 microtubule-based movement", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GAU1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GB56-1", "uniprot_id": [ { "id": "A0A9J7GB56_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GB56", "type": "external" } ], "mass": 63933.0, "length": 589, "protein_name": "Sodium-independent sulfate anion transporter", "gene_name": "Slc26a11", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: sodium-independent sulfate anion transporter isoform X4", "refseq_ac": [ { "id": "XP_027281288", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281288", "type": "external" } ], "gene_names_uniprotkb": "Slc26a11", "gene_names_refseq": "Slc26a11", "protein_names_uniprotkb": "Sodium-independent sulfate anion transporter; Solute carrier family 26 member 11", "protein_names_refseq": "LOW QUALITY PROTEIN: sodium-independent sulfate anion transporter isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100757714)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Sodium-independent anion exchanger mediating bicarbonate, chloride, sulfate and oxalate transport. Exhibits sodium-independent sulfate anion transporter activity that may cooperate with SLC26A2 to mediate DIDS-sensitive sulfate uptake into high endothelial venules endothelial cells (HEVEC). In the kidney, mediates chloride-bicarbonate exchange, facilitating V-ATPase-mediated acid secretion. May function as a chloride channel, playing an important role in moderating chloride homeostasis and neuronal activity in the cerebellum., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008271 secondary active sulfate transmembrane transporter activity;GO:0140900 chloride:bicarbonate antiporter activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane;GO:0005765 lysosomal membrane;GO:0016324 apical plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GB56-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GBA2-1", "uniprot_id": [ { "id": "A0A9J7GBA2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GBA2", "type": "external" } ], "mass": 66325.0, "length": 578, "protein_name": "La-related protein 7", "gene_name": "LOC100768885", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: la-related protein 7 isoform X2", "refseq_ac": [ { "id": "XP_027281027", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281027", "type": "external" } ], "gene_names_uniprotkb": "LOC100768885", "gene_names_refseq": "LOC100768885", "protein_names_uniprotkb": "La-related protein 7; La ribonucleoprotein domain family member 7", "protein_names_refseq": "LOW QUALITY PROTEIN: la-related protein 7 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100768885)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 4 indels ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017070 U6 snRNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006397 mRNA processing;GO:0007283 spermatogenesis;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GBA2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GBH3-1", "uniprot_id": [ { "id": "A0A9J7GBH3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GBH3", "type": "external" } ], "mass": 265355.0, "length": 2440, "protein_name": "histone acetyltransferase", "gene_name": "LOC100770451", "organism": "Hamster", "refseq_name": "histone lysine acetyltransferase CREBBP isoform X3", "refseq_ac": [ { "id": "XP_027279825", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279825", "type": "external" } ], "gene_names_uniprotkb": "LOC100770451", "gene_names_refseq": "LOC100770451", "protein_names_uniprotkb": "histone acetyltransferase; 2.3.1.48", "protein_names_refseq": "histone lysine acetyltransferase CREBBP isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100770451)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 8, "predicted_n_glycosites": 0, "predicted_o_glycosites": 8, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" } ], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0008270 zinc ion binding;GO:0031490 chromatin DNA binding;GO:0004402 histone acetyltransferase activity;GO:0140297 DNA-binding transcription factor binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005667 transcription regulator complex;GO:0000123 histone acetyltransferase complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0048511 rhythmic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GBH3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GBI0-1", "uniprot_id": [ { "id": "A0A9J7GBI0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GBI0", "type": "external" } ], "mass": 80294.0, "length": 706, "protein_name": "Heat shock protein 75 kDa, mitochondrial", "gene_name": "Trap1", "organism": "Hamster", "refseq_name": "heat shock protein 75 kDa, mitochondrial", "refseq_ac": [ { "id": "XP_027279826", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279826", "type": "external" } ], "gene_names_uniprotkb": "Trap1", "gene_names_refseq": "Trap1", "protein_names_uniprotkb": "Heat shock protein 75 kDa, mitochondrial; TNFR-associated protein 1; Tumor necrosis factor type 1 receptor-associated protein", "protein_names_refseq": "heat shock protein 75 kDa, mitochondrial", "tax_id": 10029, "disease": "", "pathway": " (cge:100763701)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0019901 protein kinase binding;GO:0051082 unfolded protein binding;GO:0016887 ATP hydrolysis activity;GO:0140662 ATP-dependent protein folding chaperone", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005759 mitochondrial matrix", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GBI0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GBI2-1", "uniprot_id": [ { "id": "A0A9J7GBI2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GBI2", "type": "external" } ], "mass": 55299.0, "length": 496, "protein_name": "mitogen-activated protein kinase kinase", "gene_name": "LOC100771767", "organism": "Hamster", "refseq_name": "dual specificity mitogen-activated protein kinase kinase 6", "refseq_ac": [ { "id": "XP_027281589", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281589", "type": "external" } ], "gene_names_uniprotkb": "LOC100771767", "gene_names_refseq": "LOC100771767", "protein_names_uniprotkb": "mitogen-activated protein kinase kinase; 2.7.12.2", "protein_names_refseq": "dual specificity mitogen-activated protein kinase kinase 6", "tax_id": 10029, "disease": "", "pathway": " (cge:100771767)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 33% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027281589.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0004708 MAP kinase kinase activity", "go_cellular_component": "", "go_biological_process": "GO:0043410 positive regulation of MAPK cascade;GO:0060048 cardiac muscle contraction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GBI2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GBP5-1", "uniprot_id": [ { "id": "A0A9J7GBP5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GBP5", "type": "external" } ], "mass": 71869.0, "length": 647, "protein_name": "RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog", "gene_name": "Rpap2", "organism": "Hamster", "refseq_name": "putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 isoform X9", "refseq_ac": [ { "id": "XP_027281714", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281714", "type": "external" } ], "gene_names_uniprotkb": "Rpap2", "gene_names_refseq": "Rpap2", "protein_names_uniprotkb": "RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog; 3.1.3.16", "protein_names_refseq": "putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 isoform X9", "tax_id": 10029, "disease": "", "pathway": " (cge:100763199)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes. Downstream of EIF2AK3/PERK, dephosphorylates ERN1, a sensor for the endoplasmic reticulum unfolded protein response (UPR), to abort failed ER-stress adaptation and trigger apoptosis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.52", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.52", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.74", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.74", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0043175 RNA polymerase core enzyme binding;GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GBP5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GDA9-1", "uniprot_id": [ { "id": "A0A9J7GDA9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GDA9", "type": "external" } ], "mass": 67161.0, "length": 621, "protein_name": "Suppressor of cytokine signaling 7", "gene_name": "Socs7", "organism": "Hamster", "refseq_name": "suppressor of cytokine signaling 7 isoform X2", "refseq_ac": [ { "id": "XP_027279969", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279969", "type": "external" } ], "gene_names_uniprotkb": "Socs7", "gene_names_refseq": "Socs7", "protein_names_uniprotkb": "Suppressor of cytokine signaling 7", "protein_names_refseq": "suppressor of cytokine signaling 7 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763757)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027279969.1. COMPLETENESS: full length., [RefSeq]; Substrate-recognition component of a cullin-5-RING E3 ubiquitin-protein ligase complex (ECS complex, also named CRL5 complex), which mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as DAB1 and IRS1. Specifically recognizes and binds phosphorylated proteins via its SH2 domain, promoting their ubiquitination. The ECS(SOCS7) complex acts as a key regulator of reelin signaling by mediating ubiquitination and degradation of phosphorylated DAB1 in the cortical plate of the developing cerebral cortex, thereby regulating neuron positioning during cortex development. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Also inhibits prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046935 1-phosphatidylinositol-3-kinase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005942 phosphatidylinositol 3-kinase complex", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0009968 negative regulation of signal transduction;GO:0046854 phosphatidylinositol phosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GDA9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GBR9-1", "uniprot_id": [ { "id": "A0A9J7GBR9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GBR9", "type": "external" } ], "mass": 72872.0, "length": 658, "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "Rnf43", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase RNF43 isoform X2", "refseq_ac": [ { "id": "XP_027282115", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282115", "type": "external" } ], "gene_names_uniprotkb": "Rnf43", "gene_names_refseq": "Rnf43", "protein_names_uniprotkb": "RING-type E3 ubiquitin transferase; 2.3.2.27", "protein_names_refseq": "E3 ubiquitin-protein ligase RNF43 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100753125)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0016055 Wnt signaling pathway;GO:0030178 negative regulation of Wnt signaling pathway;GO:0072089 stem cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GBR9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GBS4-1", "uniprot_id": [ { "id": "A0A9J7GBS4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GBS4", "type": "external" } ], "mass": 70834.0, "length": 625, "protein_name": "Signal recognition particle subunit SRP68", "gene_name": "Srp68", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: signal recognition particle subunit SRP68 isoform X2", "refseq_ac": [ { "id": "XP_027281408", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281408", "type": "external" } ], "gene_names_uniprotkb": "Srp68", "gene_names_refseq": "Srp68", "protein_names_uniprotkb": "Signal recognition particle subunit SRP68; SRP68", "protein_names_refseq": "LOW QUALITY PROTEIN: signal recognition particle subunit SRP68 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100760316)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER. The SRP complex targets the ribosome-nascent chain complex to the SRP receptor (SR), which is anchored in the ER, where SR compaction and GTPase rearrangement drive cotranslational protein translocation into the ER. Binds the signal recognition particle RNA (7SL RNA), SRP72 binds to this complex subsequently. The SRP complex possibly participates in the elongation arrest function., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005047 signal recognition particle binding;GO:0030942 endoplasmic reticulum signal peptide binding;GO:0008312 7S RNA binding", "go_cellular_component": "GO:0005786 signal recognition particle, endoplasmic reticulum targeting;GO:0005730 nucleolus;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol", "go_biological_process": "GO:0006614 SRP-dependent cotranslational protein targeting to membrane", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GBS4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GBT7-1", "uniprot_id": [ { "id": "A0A9J7GBT7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GBT7", "type": "external" } ], "mass": 72195.0, "length": 643, "protein_name": "Arachidonate--CoA ligase", "gene_name": "Slc27a4", "organism": "Hamster", "refseq_name": "long-chain fatty acid transport protein 4", "refseq_ac": [ { "id": "XP_027278913", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278913", "type": "external" } ], "gene_names_uniprotkb": "Slc27a4", "gene_names_refseq": "Slc27a4", "protein_names_uniprotkb": "Arachidonate--CoA ligase; 6.2.1.15; 6.2.1.3; Long-chain-fatty-acid--CoA ligase", "protein_names_refseq": "long-chain fatty acid transport protein 4", "tax_id": 10029, "disease": "", "pathway": " (cge:100765865)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.3", "type": "external" }, { "id": "6.2.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.15", "type": "external" }, { "id": "6.2.1.76", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.76", "type": "external" } ], "go_molecular_function": "GO:0005324 long-chain fatty acid transmembrane transporter activity;GO:0000166 nucleotide binding;GO:0047676 arachidonate-CoA ligase activity;GO:0090434 oleoyl-CoA ligase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0044539 long-chain fatty acid import into cell;GO:0001579 medium-chain fatty acid transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GBT7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GDA4-1", "uniprot_id": [ { "id": "A0A9J7GDA4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GDA4", "type": "external" } ], "mass": 161029.0, "length": 1418, "protein_name": "Telomerase-binding protein EST1A", "gene_name": "Smg6", "organism": "Hamster", "refseq_name": "telomerase-binding protein EST1A isoform X3", "refseq_ac": [ { "id": "XP_027282563", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282563", "type": "external" } ], "gene_names_uniprotkb": "Smg6", "gene_names_refseq": "Smg6", "protein_names_uniprotkb": "Telomerase-binding protein EST1A; 3.1.-.-", "protein_names_refseq": "telomerase-binding protein EST1A isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100767685)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini. May have a general role in telomere regulation. Promotes in vitro the ability of TERT to elongate telomeres. Overexpression induces telomere uncapping, chromosomal end-to-end fusions (telomeric DNA persists at the fusion points) and did not perturb TRF2 telomeric localization. Binds to the single-stranded 5'-(GTGTGG)(4)GTGT-3' telomeric DNA, but not to a telomerase RNA template component (TER)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Plays a role in nonsense-mediated mRNA decay. Is thought to provide a link to the mRNA degradation machinery as it has endonuclease activity required to initiate NMD, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation. Degrades single-stranded RNA (ssRNA), but not ssDNA or dsRNA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016787 hydrolase activity;GO:0030145 manganese ion binding;GO:0042162 telomeric DNA binding;GO:0004519 endonuclease activity;GO:0070034 telomerase RNA binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005829 cytosol;GO:0005697 telomerase holoenzyme complex;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GDA4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GC95-1", "uniprot_id": [ { "id": "A0A9J7GC95_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GC95", "type": "external" } ], "mass": 119895.0, "length": 1044, "protein_name": "Unconventional myosin-Ic", "gene_name": "Myo1c", "organism": "Hamster", "refseq_name": "unconventional myosin-Ic isoform X3", "refseq_ac": [ { "id": "XP_027282529", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282529", "type": "external" } ], "gene_names_uniprotkb": "Myo1c", "gene_names_refseq": "Myo1c", "protein_names_uniprotkb": "Unconventional myosin-Ic; Myosin I beta", "protein_names_refseq": "unconventional myosin-Ic isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100759064)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005938 cell cortex;GO:0031410 cytoplasmic vesicle;GO:0032587 ruffle membrane;GO:0005902 microvillus", "go_biological_process": "GO:1900078 positive regulation of cellular response to insulin stimulus;GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0030048 actin filament-based movement", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GC95-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GCJ5-1", "uniprot_id": [ { "id": "A0A9J7GCJ5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GCJ5", "type": "external" } ], "mass": 35249.0, "length": 330, "protein_name": "Macrosialin", "gene_name": "Cd68", "organism": "Hamster", "refseq_name": "macrosialin", "refseq_ac": [ { "id": "XP_003497226", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497226", "type": "external" } ], "gene_names_uniprotkb": "Cd68", "gene_names_refseq": "Cd68", "protein_names_uniprotkb": "Macrosialin", "protein_names_refseq": "macrosialin", "tax_id": 10029, "disease": "", "pathway": " (cge:100762586)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613643.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane", "go_biological_process": "GO:0072594 establishment of protein localization to organelle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GCJ5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GCS2-1", "uniprot_id": [ { "id": "A0A9J7GCS2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GCS2", "type": "external" } ], "mass": 192413.0, "length": 1682, "protein_name": "Clathrin heavy chain", "gene_name": "Cltc", "organism": "Hamster", "refseq_name": "clathrin heavy chain 1 isoform X1", "refseq_ac": [ { "id": "XP_007642561", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642561", "type": "external" } ], "gene_names_uniprotkb": "Cltc", "gene_names_refseq": "Cltc", "protein_names_uniprotkb": "Clathrin heavy chain", "protein_names_refseq": "clathrin heavy chain 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100756644)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 76 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614004.1) and transcript sequence (IACG01083966.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007642561.1. COMPLETENESS: full length., [RefSeq]; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network. Acts as a component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension. Plays a role in early autophagosome formation. Interaction with DNAJC6 mediates the recruitment of HSPA8 to the clathrin lattice and creates local destabilization of the lattice promoting uncoating., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity;GO:0032051 clathrin light chain binding;GO:0050750 low-density lipoprotein particle receptor binding;GO:0003725 double-stranded RNA binding;GO:1990381 ubiquitin-specific protease binding", "go_cellular_component": "GO:0005819 spindle;GO:0070062 extracellular exosome;GO:0045334 clathrin-coated endocytic vesicle;GO:0030130 clathrin coat of trans-Golgi network vesicle;GO:0071439 clathrin complex", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0006886 intracellular protein transport;GO:0006898 receptor-mediated endocytosis;GO:0048268 clathrin coat assembly;GO:0031623 receptor internalization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GCS2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GCT6-1", "uniprot_id": [ { "id": "A0A9J7GCT6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GCT6", "type": "external" } ], "mass": 162838.0, "length": 1445, "protein_name": "Inactive serine/threonine-protein kinase TEX14", "gene_name": "Tex14", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: inactive serine/threonine-protein kinase TEX14 isoform X2", "refseq_ac": [ { "id": "XP_027282130", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282130", "type": "external" } ], "gene_names_uniprotkb": "Tex14", "gene_names_refseq": "Tex14", "protein_names_uniprotkb": "Inactive serine/threonine-protein kinase TEX14; Testis-expressed sequence 14 protein; Testis-expressed sequence 14", "protein_names_refseq": "LOW QUALITY PROTEIN: inactive serine/threonine-protein kinase TEX14 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754599)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 2 indels ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Required both for the formation of intercellular bridges during meiosis and for kinetochore-microtubule attachment during mitosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells and are required for spermatogenesis and male fertility. Acts by promoting the conversion of midbodies into intercellular bridges via its interaction with CEP55: interaction with CEP55 inhibits the interaction between CEP55 and PDCD6IP/ALIX and TSG101, blocking cell abscission and leading to transform midbodies into intercellular bridges. Also plays a role during mitosis: recruited to kinetochores by PLK1 during early mitosis and regulates the maturation of the outer kinetochores and microtubule attachment. Has no protein kinase activity in vitro., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0045171 intercellular bridge;GO:0000776 kinetochore;GO:0030496 midbody", "go_biological_process": "GO:0043063 intercellular bridge organization;GO:0008608 attachment of spindle microtubules to kinetochore;GO:0051301 cell division;GO:0051306 mitotic sister chromatid separation;GO:0007094 mitotic spindle assembly checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GCT6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GCW1-1", "uniprot_id": [ { "id": "A0A9J7GCW1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GCW1", "type": "external" } ], "mass": 69859.0, "length": 626, "protein_name": "Mesothelin", "gene_name": "Msln", "organism": "Hamster", "refseq_name": "mesothelin", "refseq_ac": [ { "id": "XP_027280869", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280869", "type": "external" } ], "gene_names_uniprotkb": "Msln", "gene_names_refseq": "Msln", "protein_names_uniprotkb": "Mesothelin; Pre-pro-megakaryocyte-potentiating factor", "protein_names_refseq": "mesothelin", "tax_id": 10029, "disease": "", "pathway": " (cge:100761360)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Megakaryocyte-potentiating factor (MPF) may potentiate megakaryocyte colony formation., [UniProtKB, UniProtKB]; Membrane-anchored forms may play a role in cellular adhesion., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0098552 side of membrane", "go_biological_process": "GO:0007160 cell-matrix adhesion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GCW1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GCW7-1", "uniprot_id": [ { "id": "A0A9J7GCW7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GCW7", "type": "external" } ], "mass": 144818.0, "length": 1271, "protein_name": "Protein flightless-1 homolog", "gene_name": "Flii", "organism": "Hamster", "refseq_name": "protein flightless-1 homolog isoform X2", "refseq_ac": [ { "id": "XP_027283086", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283086", "type": "external" } ], "gene_names_uniprotkb": "Flii", "gene_names_refseq": "Flii", "protein_names_uniprotkb": "Protein flightless-1 homolog", "protein_names_refseq": "protein flightless-1 homolog isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756205)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Is a regulator of actin polymerization, required for proper myofibril organization and regulation of the length of sarcomeric thin filaments. It also plays a role in the assembly of cardiomyocyte cell adhesion complexes. Regulates cytoskeletal rearrangements involved in cytokinesis and cell migration, by inhibiting Rac1-dependent paxillin phosphorylation. May play a role as coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and acts in cooperation with NCOA2 and CARM1. Involved in estrogen hormone signaling., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005925 focal adhesion;GO:0015629 actin cytoskeleton", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0051016 barbed-end actin filament capping;GO:0008154 actin polymerization or depolymerization;GO:0051014 actin filament severing;GO:0030239 myofibril assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GCW7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GCX1-1", "uniprot_id": [ { "id": "A0A9J7GCX1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GCX1", "type": "external" } ], "mass": 52340.0, "length": 475, "protein_name": "Serine hydroxymethyltransferase", "gene_name": "Shmt1", "organism": "Hamster", "refseq_name": "serine hydroxymethyltransferase, cytosolic", "refseq_ac": [ { "id": "XP_027283085", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283085", "type": "external" } ], "gene_names_uniprotkb": "Shmt1", "gene_names_refseq": "Shmt1", "protein_names_uniprotkb": "Serine hydroxymethyltransferase; 2.1.2.1", "protein_names_refseq": "serine hydroxymethyltransferase, cytosolic", "tax_id": 10029, "disease": "", "pathway": " (cge:100773080)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Interconversion of serine and glycine., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.2.1", "type": "external" } ], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0004372 glycine hydroxymethyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion", "go_biological_process": "GO:0035999 tetrahydrofolate interconversion;GO:0019264 glycine biosynthetic process from serine", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GCX1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GCY9-1", "uniprot_id": [ { "id": "A0A9J7GCY9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GCY9", "type": "external" } ], "mass": 20487.0, "length": 185, "protein_name": "Nucleoside diphosphate kinase", "gene_name": "Nme4", "organism": "Hamster", "refseq_name": "nucleoside diphosphate kinase, mitochondrial isoform X1", "refseq_ac": [ { "id": "XP_027280926", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280926", "type": "external" } ], "gene_names_uniprotkb": "Nme4", "gene_names_refseq": "Nme4", "protein_names_uniprotkb": "Nucleoside diphosphate kinase; 2.7.4.6", "protein_names_refseq": "nucleoside diphosphate kinase, mitochondrial isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100757593)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "2.7.4.14", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.14", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "2.7.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.10", "type": "external" }, { "id": "2.7.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.4", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004550 nucleoside diphosphate kinase activity", "go_cellular_component": "GO:0005758 mitochondrial intermembrane space;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006183 GTP biosynthetic process;GO:0006228 UTP biosynthetic process;GO:0006241 CTP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GCY9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GD29-1", "uniprot_id": [ { "id": "A0A9J7GD29_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GD29", "type": "external" } ], "mass": 46641.0, "length": 419, "protein_name": "E3 ubiquitin-protein ligase RNF135", "gene_name": "Rnf135", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase RNF135 isoform X2", "refseq_ac": [ { "id": "XP_027282323", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282323", "type": "external" } ], "gene_names_uniprotkb": "Rnf135", "gene_names_refseq": "Rnf135", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RNF135; 2.3.2.27; RING finger protein 135; RING-type E3 ubiquitin transferase RNF135", "protein_names_refseq": "E3 ubiquitin-protein ligase RNF135 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772496)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0043021 ribonucleoprotein complex binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0000209 protein polyubiquitination;GO:0039529 RIG-I signaling pathway;GO:0140374 antiviral innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GD29-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GD34-1", "uniprot_id": [ { "id": "A0A9J7GD34_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GD34", "type": "external" } ], "mass": 153383.0, "length": 1373, "protein_name": "Adenylate cyclase type 9", "gene_name": "Adcy9", "organism": "Hamster", "refseq_name": "adenylate cyclase type 9 isoform X1", "refseq_ac": [ { "id": "XP_027279823", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279823", "type": "external" } ], "gene_names_uniprotkb": "Adcy9", "gene_names_refseq": "Adcy9", "protein_names_uniprotkb": "Adenylate cyclase type 9; 4.6.1.1; ATP pyrophosphate-lyase 9; Adenylate cyclase type IX; Adenylyl cyclase 9", "protein_names_refseq": "adenylate cyclase type 9 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100751372)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:4.6.1.1", "type": "external" } ], "go_molecular_function": "GO:0004016 adenylate cyclase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006171 cAMP biosynthetic process;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GD34-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GD53-1", "uniprot_id": [ { "id": "A0A9J7GD53_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GD53", "type": "external" } ], "mass": 133565.0, "length": 1205, "protein_name": "Tubulin-specific chaperone D", "gene_name": "Tbcd", "organism": "Hamster", "refseq_name": "tubulin-specific chaperone D isoform X1", "refseq_ac": [ { "id": "XP_007648838", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007648838", "type": "external" } ], "gene_names_uniprotkb": "Tbcd", "gene_names_refseq": "Tbcd", "protein_names_uniprotkb": "Tubulin-specific chaperone D; Beta-tubulin cofactor D; Tubulin-folding cofactor D", "protein_names_refseq": "tubulin-specific chaperone D isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100753552)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases assembly gap :: added 134 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614801.1) and transcript sequence (IACG01004717.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007648838.2. COMPLETENESS: full length., [RefSeq]; Tubulin-folding protein implicated in the first step of the tubulin folding pathway and required for tubulin complex assembly. Involved in the regulation of microtubule polymerization or depolymerization, it modulates microtubule dynamics by capturing GTP-bound beta-tubulin (TUBB). Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Acts as a GTPase-activating protein (GAP) for ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes epithelial cell detachment, a process antagonized by ARL2. Induces tight adherens and tight junctions disassembly at the lateral cell membrane. Required for correct assembly and maintenance of the mitotic spindle, and proper progression of mitosis. Involved in neuron morphogenesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0048487 beta-tubulin binding", "go_cellular_component": "GO:0005813 centrosome;GO:0005912 adherens junction;GO:0005923 bicellular tight junction;GO:0016328 lateral plasma membrane", "go_biological_process": "GO:0070830 bicellular tight junction assembly;GO:0000226 microtubule cytoskeleton organization;GO:0007021 tubulin complex assembly;GO:0034333 adherens junction assembly;GO:0007023 post-chaperonin tubulin folding pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GD53-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GD76-1", "uniprot_id": [ { "id": "A0A9J7GD76_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GD76", "type": "external" } ], "mass": 116055.0, "length": 1001, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Taok1", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase TAO1 isoform X2", "refseq_ac": [ { "id": "XP_027282448", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282448", "type": "external" } ], "gene_names_uniprotkb": "Taok1", "gene_names_refseq": "Taok1", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase TAO1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100758772)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006281 DNA repair;GO:0051493 regulation of cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GD76-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GD80-1", "uniprot_id": [ { "id": "A0A9J7GD80_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GD80", "type": "external" } ], "mass": 85663.0, "length": 765, "protein_name": "Long-chain-fatty-acid--CoA ligase", "gene_name": "Acsl6", "organism": "Hamster", "refseq_name": "long-chain-fatty-acid--CoA ligase 6 isoform X3", "refseq_ac": [ { "id": "XP_027283296", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283296", "type": "external" } ], "gene_names_uniprotkb": "Acsl6", "gene_names_refseq": "Acsl6", "protein_names_uniprotkb": "Long-chain-fatty-acid--CoA ligase; 6.2.1.15; 6.2.1.3; Acyl-CoA synthetase; Long-chain acyl-CoA synthetase", "protein_names_refseq": "long-chain-fatty-acid--CoA ligase 6 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100762894)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.3", "type": "external" }, { "id": "6.2.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.15", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0047676 arachidonate-CoA ligase activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GD80-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GDB9-1", "uniprot_id": [ { "id": "A0A9J7GDB9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GDB9", "type": "external" } ], "mass": 47771.0, "length": 438, "protein_name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 1", "gene_name": "Dph1", "organism": "Hamster", "refseq_name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 isoform X1", "refseq_ac": [ { "id": "XP_003507319", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507319", "type": "external" } ], "gene_names_uniprotkb": "Dph1", "gene_names_refseq": "Dph1", "protein_names_uniprotkb": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; 2.5.1.108; Diphthamide biosynthesis protein 1; Diphtheria toxin resistance protein 1; Ovarian cancer-associated gene 1 protein homolog; S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1", "protein_names_refseq": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100765648)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614347.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.5.1.108", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.108", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0051536 iron-sulfur cluster binding;GO:0090560 2-(3-amino-3-carboxypropyl)histidine synthase activity;GO:0051539 4 iron, 4 sulfur cluster binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm;GO:0120513 2-(3-amino-3-carboxypropyl)histidine synthase complex", "go_biological_process": "GO:0017183 protein histidyl modification to diphthamide", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GDB9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GDU4-1", "uniprot_id": [ { "id": "A0A9J7GDU4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GDU4", "type": "external" } ], "mass": 48260.0, "length": 427, "protein_name": "Inward rectifier potassium channel 2", "gene_name": "Kcnj2", "organism": "Hamster", "refseq_name": "inward rectifier potassium channel 2", "refseq_ac": [ { "id": "XP_027281585", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281585", "type": "external" } ], "gene_names_uniprotkb": "Kcnj2", "gene_names_refseq": "Kcnj2", "protein_names_uniprotkb": "Inward rectifier potassium channel 2; Inward rectifier K(+) channel Kir2.1; Potassium channel, inwardly rectifying subfamily J member 2", "protein_names_refseq": "inward rectifier potassium channel 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754461)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005242 inward rectifier potassium channel activity", "go_cellular_component": "GO:0030315 T-tubule;GO:0034702 monoatomic ion channel complex", "go_biological_process": "GO:0034765 regulation of monoatomic ion transmembrane transport;GO:1990573 potassium ion import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GDU4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GE03-1", "uniprot_id": [ { "id": "A0A9J7GE03_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GE03", "type": "external" } ], "mass": 48413.0, "length": 443, "protein_name": "Keratin, type I cytoskeletal 27", "gene_name": "LOC100759216", "organism": "Hamster", "refseq_name": "keratin, type I cytoskeletal 27 isoform X2", "refseq_ac": [ { "id": "XP_027283543", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283543", "type": "external" } ], "gene_names_uniprotkb": "LOC100759216", "gene_names_refseq": "LOC100759216", "protein_names_uniprotkb": "Keratin, type I cytoskeletal 27; Cytokeratin-27; Keratin-27; Type I inner root sheath-specific keratin-K25irs3", "protein_names_refseq": "keratin, type I cytoskeletal 27 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100759216)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005882 intermediate filament", "go_biological_process": "GO:0030855 epithelial cell differentiation;GO:0045109 intermediate filament organization;GO:0031069 hair follicle morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GE03-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GE16-1", "uniprot_id": [ { "id": "A0A9J7GE16_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GE16", "type": "external" } ], "mass": 87981.0, "length": 769, "protein_name": "Signal transducer and activator of transcription", "gene_name": "Stat3", "organism": "Hamster", "refseq_name": "signal transducer and activator of transcription 3 isoform X9", "refseq_ac": [ { "id": "XP_027283930", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283930", "type": "external" } ], "gene_names_uniprotkb": "Stat3", "gene_names_refseq": "Stat3", "protein_names_uniprotkb": "Signal transducer and activator of transcription", "protein_names_refseq": "signal transducer and activator of transcription 3 isoform X9", "tax_id": 10029, "disease": "", "pathway": " (cge:100755865)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 96 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) and transcript sequence (IACG01067607.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006954 inflammatory response;GO:0007165 signal transduction;GO:0010628 positive regulation of gene expression;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GE16-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GE24-1", "uniprot_id": [ { "id": "A0A9J7GE24_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GE24", "type": "external" } ], "mass": 395733.0, "length": 3510, "protein_name": "Unconventional myosin-XV", "gene_name": "Myo15a", "organism": "Hamster", "refseq_name": "unconventional myosin-XV isoform X2", "refseq_ac": [ { "id": "XP_027283093", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283093", "type": "external" } ], "gene_names_uniprotkb": "Myo15a", "gene_names_refseq": "Myo15a", "protein_names_uniprotkb": "Unconventional myosin-XV; Unconventional myosin-15", "protein_names_refseq": "unconventional myosin-XV isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100755330)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Required for the arrangement of stereocilia in mature hair bundles., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0005524 ATP binding;GO:0003774 cytoskeletal motor activity", "go_cellular_component": "GO:0032420 stereocilium;GO:0016459 myosin complex", "go_biological_process": "GO:0007605 sensory perception of sound", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GE24-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GE25-1", "uniprot_id": [ { "id": "A0A9J7GE25_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GE25", "type": "external" } ], "mass": 120831.0, "length": 1101, "protein_name": "ATP-citrate synthase", "gene_name": "Acly", "organism": "Hamster", "refseq_name": "ATP-citrate synthase isoform X3", "refseq_ac": [ { "id": "XP_027283954", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283954", "type": "external" } ], "gene_names_uniprotkb": "Acly", "gene_names_refseq": "Acly", "protein_names_uniprotkb": "ATP-citrate synthase; 2.3.3.8; ATP-citrate (pro-S-)-lyase; Citrate cleavage enzyme", "protein_names_refseq": "ATP-citrate synthase isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100773325)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate in multiple biochemical reactions in protein, carbohydrate and lipid metabolism., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.3.8", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.8", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0003878 ATP citrate synthase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006101 citrate metabolic process;GO:0006633 fatty acid biosynthetic process;GO:0006085 acetyl-CoA biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GE25-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GE31-1", "uniprot_id": [ { "id": "A0A9J7GE31_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GE31", "type": "external" } ], "mass": 118714.0, "length": 1035, "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "Nlrp3", "organism": "Hamster", "refseq_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X2", "refseq_ac": [ { "id": "XP_027283134", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283134", "type": "external" } ], "gene_names_uniprotkb": "Nlrp3", "gene_names_refseq": "Nlrp3", "protein_names_uniprotkb": "NACHT, LRR and PYD domains-containing protein 3", "protein_names_refseq": "NACHT, LRR and PYD domains-containing protein 3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100759809)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Independently of inflammasome activation, regulates the differentiation of T helper 2 (Th2) cells and has a role in Th2 cell-dependent asthma and tumor growth. During Th2 differentiation, required for optimal IRF4 binding to IL4 promoter and for IRF4-dependent IL4 transcription. Binds to the consensus DNA sequence 5'-GRRGGNRGAG-3'. May also participate in the transcription of IL5, IL13, GATA3, CCR3, CCR4 and MAF., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0043565 sequence-specific DNA binding;GO:0140297 DNA-binding transcription factor binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005576 extracellular region;GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:0002674 negative regulation of acute inflammatory response;GO:1901223 negative regulation of non-canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GE31-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GE95-1", "uniprot_id": [ { "id": "A0A9J7GE95_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GE95", "type": "external" } ], "mass": 221856.0, "length": 1954, "protein_name": "ATP-dependent chromatin remodeler CHD4", "gene_name": "Chd4", "organism": "Hamster", "refseq_name": "chromodomain-helicase-DNA-binding protein 4 isoform X2", "refseq_ac": [ { "id": "XP_027284091", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284091", "type": "external" } ], "gene_names_uniprotkb": "Chd4", "gene_names_refseq": "Chd4", "protein_names_uniprotkb": "ATP-dependent chromatin remodeler CHD4; Chromo domain-containing protein 4", "protein_names_refseq": "chromodomain-helicase-DNA-binding protein 4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754178)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; ATP-dependent chromatin-remodeling factor that binds and distorts nucleosomal DNA. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Localizes to acetylated damaged chromatin in a ZMYND8-dependent manner, to promote transcriptional repression and double-strand break repair by homologous recombination. Involved in neurogenesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005813 centrosome;GO:0016581 NuRD complex", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GE95-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GE99-1", "uniprot_id": [ { "id": "A0A9J7GE99_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GE99", "type": "external" } ], "mass": 101541.0, "length": 907, "protein_name": "Glutamate receptor", "gene_name": "Gria1", "organism": "Hamster", "refseq_name": "glutamate receptor 1 isoform X3", "refseq_ac": [ { "id": "XP_027283249", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283249", "type": "external" } ], "gene_names_uniprotkb": "Gria1", "gene_names_refseq": "Gria1", "protein_names_uniprotkb": "Glutamate receptor", "protein_names_refseq": "glutamate receptor 1 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100769392)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0022824 transmitter-gated monoatomic ion channel activity", "go_cellular_component": "GO:0032281 AMPA glutamate receptor complex;GO:0098839 postsynaptic density membrane", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GE99-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GEE0-1", "uniprot_id": [ { "id": "A0A9J7GEE0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GEE0", "type": "external" } ], "mass": 153665.0, "length": 1312, "protein_name": "DNA repair protein RAD50", "gene_name": "Rad50", "organism": "Hamster", "refseq_name": "DNA repair protein RAD50 isoform X2", "refseq_ac": [ { "id": "XP_027283327", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283327", "type": "external" } ], "gene_names_uniprotkb": "Rad50", "gene_names_refseq": "Rad50", "protein_names_uniprotkb": "DNA repair protein RAD50", "protein_names_refseq": "DNA repair protein RAD50 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100755349)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0003691 double-stranded telomeric DNA binding;GO:0051880 G-quadruplex DNA binding", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0000781 chromosome, telomeric region;GO:0030870 Mre11 complex", "go_biological_process": "GO:0006302 double-strand break repair;GO:0007004 telomere maintenance via telomerase;GO:0070192 chromosome organization involved in meiotic cell cycle;GO:0000722 telomere maintenance via recombination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GEE0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GEK6-1", "uniprot_id": [ { "id": "A0A9J7GEK6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GEK6", "type": "external" } ], "mass": 69741.0, "length": 616, "protein_name": "Bromodomain-containing protein 4-like", "gene_name": "LOC113836825", "organism": "Hamster", "refseq_name": "bromodomain-containing protein 4-like", "refseq_ac": [ { "id": "XP_027244318", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244318", "type": "external" } ], "gene_names_uniprotkb": "LOC113836825; LOC113832446; LOC113832901; LOC113834149; LOC113834164; LOC113834352; LOC113834409; LOC113834420; LOC113835009; LOC113835041; LOC113835055; LOC113835330; LOC113835850; LOC113837528; LOC118239448", "gene_names_refseq": "LOC113832446", "protein_names_uniprotkb": "Bromodomain-containing protein 4-like", "protein_names_refseq": "bromodomain-containing protein 4-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113832446); (cge:113832901); (cge:113834149); (cge:113834164); (cge:113834352); (cge:113834409); (cge:113834420); (cge:113835009); (cge:113835041); (cge:113835055); (cge:113835330); (cge:113835850); (cge:113836825); (cge:113837528); (cge:118239448)", "pathway_count": 15, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003676 nucleic acid binding", "go_cellular_component": "", "go_biological_process": "GO:0019068 virion assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GEK6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GEK9-1", "uniprot_id": [ { "id": "A0A9J7GEK9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GEK9", "type": "external" } ], "mass": 52360.0, "length": 479, "protein_name": "Keratin, type I cytoskeletal 14", "gene_name": "Krt14", "organism": "Hamster", "refseq_name": "keratin, type I cytoskeletal 14 isoform X1", "refseq_ac": [ { "id": "XP_027283512", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283512", "type": "external" } ], "gene_names_uniprotkb": "Krt14", "gene_names_refseq": "Krt14", "protein_names_uniprotkb": "Keratin, type I cytoskeletal 14; Cytokeratin-14; Keratin-14", "protein_names_refseq": "keratin, type I cytoskeletal 14 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100760043)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0045095 keratin filament", "go_biological_process": "GO:0030855 epithelial cell differentiation;GO:0045109 intermediate filament organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GEK9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GEM4-1", "uniprot_id": [ { "id": "A0A9J7GEM4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GEM4", "type": "external" } ], "mass": 82771.0, "length": 746, "protein_name": "Protein phosphatase 1E", "gene_name": "Ppm1e", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: protein phosphatase 1E isoform X2", "refseq_ac": [ { "id": "XP_027282143", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282143", "type": "external" } ], "gene_names_uniprotkb": "Ppm1e", "gene_names_refseq": "Ppm1e", "protein_names_uniprotkb": "Protein phosphatase 1E; 3.1.3.16; Ca(2+)/calmodulin-dependent protein kinase phosphatase N; CaMKP-nucleus; Partner of PIX 1; Partner of PIX-alpha", "protein_names_refseq": "LOW QUALITY PROTEIN: protein phosphatase 1E isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:113836769)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 2 indels ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.52", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.52", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.74", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.74", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GEM4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GEW4-1", "uniprot_id": [ { "id": "A0A9J7GEW4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GEW4", "type": "external" } ], "mass": 47343.0, "length": 412, "protein_name": "Corticotropin-releasing factor receptor 1", "gene_name": "LOC100769844", "organism": "Hamster", "refseq_name": "corticotropin-releasing factor receptor 1 isoform X3", "refseq_ac": [ { "id": "XP_027283713", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283713", "type": "external" } ], "gene_names_uniprotkb": "LOC100769844", "gene_names_refseq": "LOC100769844", "protein_names_uniprotkb": "Corticotropin-releasing factor receptor 1; Corticotropin-releasing hormone receptor 1", "protein_names_refseq": "corticotropin-releasing factor receptor 1 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100769844)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027283713.1. COMPLETENESS: full length., [RefSeq]; G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008528 G protein-coupled peptide receptor activity;GO:0015056 corticotrophin-releasing factor receptor activity;GO:0051424 corticotropin-releasing hormone binding;GO:0043404 corticotropin-releasing hormone receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043005 neuron projection", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0030534 adult behavior;GO:0035640 exploration behavior;GO:0051049 regulation of transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GEW4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GEY3-1", "uniprot_id": [ { "id": "A0A9J7GEY3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GEY3", "type": "external" } ], "mass": 64043.0, "length": 570, "protein_name": "Frizzled-2", "gene_name": "Fzd2", "organism": "Hamster", "refseq_name": "frizzled-2 isoform X2", "refseq_ac": [ { "id": "XP_027283794", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283794", "type": "external" } ], "gene_names_uniprotkb": "Fzd2", "gene_names_refseq": "Fzd2", "protein_names_uniprotkb": "Frizzled-2", "protein_names_refseq": "frizzled-2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763109)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0017147 Wnt-protein binding;GO:0042813 Wnt receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0060070 canonical Wnt signaling pathway;GO:0035567 non-canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GEY3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GF01-1", "uniprot_id": [ { "id": "A0A9J7GF01_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GF01", "type": "external" } ], "mass": 152504.0, "length": 1378, "protein_name": "Carboxypeptidase D", "gene_name": "Cpd", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: carboxypeptidase D isoform X2", "refseq_ac": [ { "id": "XP_027282494", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282494", "type": "external" } ], "gene_names_uniprotkb": "Cpd", "gene_names_refseq": "Cpd", "protein_names_uniprotkb": "Carboxypeptidase D; 3.4.17.22; Metallocarboxypeptidase D; gp180", "protein_names_refseq": "LOW QUALITY PROTEIN: carboxypeptidase D isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100757331)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Functions in the processing of proteins and peptides in the secretory pathway. Mechanistically, cleaves exclusively C-terminal basic residues. By removing terminal residues, can modulate the activity, stability, and receptor-binding properties of bioactive peptides., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004181 metallocarboxypeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane", "go_biological_process": "GO:0016485 protein processing;GO:0006518 peptide metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GF01-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GI90-1", "uniprot_id": [ { "id": "A0A9J7GI90_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GI90", "type": "external" } ], "mass": 73048.0, "length": 657, "protein_name": "Amyloid-like protein 1 isoform X2", "gene_name": "Aplp1", "organism": "Hamster", "refseq_name": "amyloid-like protein 1 isoform X2", "refseq_ac": [ { "id": "XP_027287070", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287070", "type": "external" } ], "gene_names_uniprotkb": "Aplp1", "gene_names_refseq": "Aplp1", "protein_names_uniprotkb": "Amyloid-like protein 1 isoform X2", "protein_names_refseq": "amyloid-like protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100773034)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008201 heparin binding;GO:0042802 identical protein binding;GO:0046914 transition metal ion binding;GO:0031694 alpha-2A adrenergic receptor binding;GO:0031696 alpha-2C adrenergic receptor binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0007409 axonogenesis;GO:0071874 cellular response to norepinephrine stimulus;GO:0007417 central nervous system development;GO:0106072 negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GI90-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GN69-1", "uniprot_id": [ { "id": "A0A9J7GN69_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GN69", "type": "external" } ], "mass": 60305.0, "length": 567, "protein_name": "OTU domain-containing protein 5", "gene_name": "Otud5", "organism": "Hamster", "refseq_name": "OTU domain-containing protein 5 isoform X1", "refseq_ac": [ { "id": "XP_007643821", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643821", "type": "external" } ], "gene_names_uniprotkb": "Otud5", "gene_names_refseq": "Otud5", "protein_names_uniprotkb": "OTU domain-containing protein 5; 3.4.19.12; Deubiquitinating enzyme A", "protein_names_refseq": "OTU domain-containing protein 5 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100761947)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 482 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614122.1) and transcript sequence (IACG01041108.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007643821.1. COMPLETENESS: full length., [RefSeq]; Deubiquitinating enzyme that functions as a negative regulator of the innate immune system. Has peptidase activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Can also cleave 'Lys-11'-linked ubiquitin chains (in vitro). Acts via TRAF3 deubiquitination and subsequent suppression of type I interferon (IFN) production. Controls neuroectodermal differentiation through cleaving 'Lys-48'-linked ubiquitin chains to counteract degradation of select chromatin regulators such as ARID1A, HDAC2 and HCF1. Acts as a positive regulator of mTORC1 and mTORC2 signaling following phosphorylation by MTOR: acts by mediating deubiquitination of BTRC, leading to its stability., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity;GO:0061578 K63-linked deubiquitinase activity;GO:1990380 K48-linked deubiquitinase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0006508 proteolysis;GO:0032496 response to lipopolysaccharide;GO:0070536 protein K63-linked deubiquitination;GO:0090090 negative regulation of canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GN69-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GN20-1", "uniprot_id": [ { "id": "A0A9J7GN20_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GN20", "type": "external" } ], "mass": 60615.0, "length": 548, "protein_name": "Metalloprotease TIKI", "gene_name": "Trabd2b", "organism": "Hamster", "refseq_name": "metalloprotease TIKI2 isoform X5", "refseq_ac": [ { "id": "XP_035295606", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295606", "type": "external" } ], "gene_names_uniprotkb": "Trabd2b", "gene_names_refseq": "Trabd2b", "protein_names_uniprotkb": "Metalloprotease TIKI; 3.4.-.-; TRAB domain-containing protein 2", "protein_names_refseq": "metalloprotease TIKI2 isoform X5", "tax_id": 10029, "disease": "", "pathway": " (cge:100758139)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding;GO:0017147 Wnt-protein binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0031090 organelle membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0031334 positive regulation of protein-containing complex assembly;GO:0016055 Wnt signaling pathway;GO:0030178 negative regulation of Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GN20-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GGK0-1", "uniprot_id": [ { "id": "A0A9J7GGK0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GGK0", "type": "external" } ], "mass": 186418.0, "length": 1643, "protein_name": "Cholesterol transporter ABCA5", "gene_name": "Abca5", "organism": "Hamster", "refseq_name": "ATP-binding cassette sub-family A member 5 isoform X1", "refseq_ac": [ { "id": "XP_027281590", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281590", "type": "external" } ], "gene_names_uniprotkb": "Abca5", "gene_names_refseq": "Abca5", "protein_names_uniprotkb": "Cholesterol transporter ABCA5; ATP-binding cassette sub-family A member 5", "protein_names_refseq": "ATP-binding cassette sub-family A member 5 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100772052)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cholesterol efflux transporter in macrophages that is responsible for APOAI/high-density lipoproteins (HDL) formation at the plasma membrane under high cholesterol levels and participates in reverse cholesterol transport. May play a role in the processing of autolysosomes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005319 lipid transporter activity;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0140359 ABC-type transporter activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005886 plasma membrane;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane", "go_biological_process": "GO:0008203 cholesterol metabolic process;GO:0010745 negative regulation of macrophage derived foam cell differentiation;GO:0033344 cholesterol efflux;GO:0034375 high-density lipoprotein particle remodeling;GO:0042632 cholesterol homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GGK0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GIW8-1", "uniprot_id": [ { "id": "A0A9J7GIW8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GIW8", "type": "external" } ], "mass": 29148.0, "length": 262, "protein_name": "FXYD domain-containing ion transport regulator", "gene_name": "LOC103162417", "organism": "Hamster", "refseq_name": "FXYD domain-containing ion transport regulator 5 isoform X1", "refseq_ac": [ { "id": "XP_027286905", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286905", "type": "external" } ], "gene_names_uniprotkb": "LOC103162417", "gene_names_refseq": "LOC103162417", "protein_names_uniprotkb": "FXYD domain-containing ion transport regulator", "protein_names_refseq": "FXYD domain-containing ion transport regulator 5 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:103162417)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. May increase NKA activity by increasing the apparent affinity for Na(+). Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017080 sodium channel regulator activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0006813 potassium ion transport;GO:0006814 sodium ion transport;GO:0043269 regulation of monoatomic ion transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GIW8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GQA1-1", "uniprot_id": [ { "id": "A0A9J7GQA1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GQA1", "type": "external" } ], "mass": 77196.0, "length": 695, "protein_name": "F-BAR and double SH3 domains protein 1", "gene_name": "Fchsd1", "organism": "Hamster", "refseq_name": "F-BAR and double SH3 domains protein 1 isoform X2", "refseq_ac": [ { "id": "XP_035296061", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035296061", "type": "external" } ], "gene_names_uniprotkb": "Fchsd1", "gene_names_refseq": "Fchsd1", "protein_names_uniprotkb": "F-BAR and double SH3 domains protein 1; Protein nervous wreck 2", "protein_names_refseq": "F-BAR and double SH3 domains protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100752340)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Promotes actin polymerization mediated by SNX9 and WASL., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008289 lipid binding", "go_cellular_component": "GO:0005829 cytosol;GO:0031594 neuromuscular junction;GO:0043204 perikaryon;GO:0055037 recycling endosome;GO:0042995 cell projection", "go_biological_process": "GO:0007274 neuromuscular synaptic transmission;GO:0061024 membrane organization;GO:0030838 positive regulation of actin filament polymerization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GQA1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GLV5-1", "uniprot_id": [ { "id": "A0A9J7GLV5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GLV5", "type": "external" } ], "mass": 162978.0, "length": 1477, "protein_name": "[histone H3]-trimethyl-L-lysine(27) demethylase", "gene_name": "Kdm6a", "organism": "Hamster", "refseq_name": "lysine-specific demethylase 6A isoform X15", "refseq_ac": [ { "id": "XP_027289100", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289100", "type": "external" } ], "gene_names_uniprotkb": "Kdm6a", "gene_names_refseq": "Kdm6a", "protein_names_uniprotkb": "[histone H3]-trimethyl-L-lysine(27) demethylase; 1.14.11.68", "protein_names_refseq": "lysine-specific demethylase 6A isoform X15", "tax_id": 10029, "disease": "", "pathway": " (cge:100758834)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.68", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.68", "type": "external" } ], "go_molecular_function": "GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0031490 chromatin DNA binding;GO:0071558 histone H3K27me2/H3K27me3 demethylase activity", "go_cellular_component": "GO:0044666 MLL3/4 complex", "go_biological_process": "GO:0003007 heart morphogenesis;GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GLV5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GKU4-1", "uniprot_id": [ { "id": "A0A9J7GKU4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GKU4", "type": "external" } ], "mass": 97365.0, "length": 872, "protein_name": "Caprin-2", "gene_name": "Caprin2", "organism": "Hamster", "refseq_name": "caprin-2 isoform X2", "refseq_ac": [ { "id": "XP_027285849", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285849", "type": "external" } ], "gene_names_uniprotkb": "Caprin2", "gene_names_refseq": "Caprin2", "protein_names_uniprotkb": "Caprin-2; C1q domain-containing protein 1; Cytoplasmic activation/proliferation-associated protein 2; RNA granule protein 140", "protein_names_refseq": "caprin-2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762439)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Promotes phosphorylation of the Wnt coreceptor LRP6, leading to increased activity of the canonical Wnt signaling pathway. Facilitates constitutive LRP6 phosphorylation by CDK14/CCNY during G2/M stage of the cell cycle, which may potentiate cells for Wnt signaling. May regulate the transport and translation of mRNAs, modulating for instance the expression of proteins involved in synaptic plasticity in neurons. Involved in regulation of growth as erythroblasts shift from a highly proliferative state towards their terminal phase of differentiation. May be involved in apoptosis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0005102 signaling receptor binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0030154 cell differentiation;GO:0017148 negative regulation of translation;GO:0090263 positive regulation of canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GKU4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QEZ1-1", "uniprot_id": [ { "id": "A0A8C2QEZ1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QEZ1", "type": "external" } ], "mass": 39713.0, "length": 345, "protein_name": "Ubiquitin thioesterase otulin isoform X4", "gene_name": "Otulin", "organism": "Hamster", "refseq_name": "ubiquitin thioesterase otulin isoform X4", "refseq_ac": [ { "id": "XP_027255851", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255851", "type": "external" } ], "gene_names_uniprotkb": "Otulin", "gene_names_refseq": "Otulin", "protein_names_uniprotkb": "Ubiquitin thioesterase otulin isoform X4", "protein_names_refseq": "ubiquitin thioesterase otulin isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100772832)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0071797 LUBAC complex", "go_biological_process": "GO:0045087 innate immune response;GO:0050728 negative regulation of inflammatory response;GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway;GO:1990108 protein linear deubiquitination;GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QEZ1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QFT1-1", "uniprot_id": [ { "id": "A0A8C2QFT1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QFT1", "type": "external" } ], "mass": 58214.0, "length": 534, "protein_name": "ADP-ribosylation factor GTPase-activating protein 2", "gene_name": "Arfgap2", "organism": "Hamster", "refseq_name": "ADP-ribosylation factor GTPase-activating protein 2 isoform X1", "refseq_ac": [ { "id": "XP_007608349", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007608349", "type": "external" } ], "gene_names_uniprotkb": "Arfgap2", "gene_names_refseq": "Arfgap2", "protein_names_uniprotkb": "ADP-ribosylation factor GTPase-activating protein 2; Zinc finger protein 289", "protein_names_refseq": "ADP-ribosylation factor GTPase-activating protein 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100755528)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613646.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0048205 COPI coating of Golgi vesicle;GO:0015031 protein transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QFT1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QND0-1", "uniprot_id": [ { "id": "A0A8C2QND0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QND0", "type": "external" } ], "mass": 50631.0, "length": 445, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Sgk1", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase Sgk1 isoform X2", "refseq_ac": [ { "id": "XP_027257707", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257707", "type": "external" } ], "gene_names_uniprotkb": "Sgk1", "gene_names_refseq": "Sgk1", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase Sgk1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100771433)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QND0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GI85-1", "uniprot_id": [ { "id": "A0A9J7GI85_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GI85", "type": "external" } ], "mass": 63269.0, "length": 570, "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "Marchf8", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase MARCHF8 isoform X1", "refseq_ac": [ { "id": "XP_027285007", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285007", "type": "external" } ], "gene_names_uniprotkb": "Marchf8", "gene_names_refseq": "Marchf8", "protein_names_uniprotkb": "RING-type E3 ubiquitin transferase; 2.3.2.27", "protein_names_refseq": "E3 ubiquitin-protein ligase MARCHF8 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100772199)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0031901 early endosome membrane", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0002495 antigen processing and presentation of peptide antigen via MHC class II", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GI85-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QPB4-1", "uniprot_id": [ { "id": "A0A8C2QPB4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QPB4", "type": "external" } ], "mass": 69427.0, "length": 644, "protein_name": "Zinc finger protein 746 isoform X2", "gene_name": "Znf746", "organism": "Hamster", "refseq_name": "zinc finger protein 746 isoform X1", "refseq_ac": [ { "id": "XP_007650770", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650770", "type": "external" } ], "gene_names_uniprotkb": "Znf746", "gene_names_refseq": "Znf746", "protein_names_uniprotkb": "Zinc finger protein 746 isoform X2", "protein_names_refseq": "zinc finger protein 746 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100762378)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 155 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615359.1) and transcript sequence (IACG01027246.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007650770.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0000122 negative regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QPB4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GMS7-1", "uniprot_id": [ { "id": "A0A9J7GMS7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GMS7", "type": "external" } ], "mass": 61355.0, "length": 569, "protein_name": "Transcription factor RelB", "gene_name": "Relb", "organism": "Hamster", "refseq_name": "transcription factor RelB isoform X3", "refseq_ac": [ { "id": "XP_027286689", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286689", "type": "external" } ], "gene_names_uniprotkb": "Relb", "gene_names_refseq": "Relb", "protein_names_uniprotkb": "Transcription factor RelB", "protein_names_refseq": "transcription factor RelB isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100752828)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0019901 protein kinase binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005654 nucleoplasm;GO:0005813 centrosome;GO:0045202 synapse", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0034097 response to cytokine", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GMS7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GMX7-1", "uniprot_id": [ { "id": "A0A9J7GMX7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GMX7", "type": "external" } ], "mass": 156399.0, "length": 1407, "protein_name": "Ubiquitin conjugation factor E4", "gene_name": "Ube4b", "organism": "Hamster", "refseq_name": "ubiquitin conjugation factor E4 B isoform X2", "refseq_ac": [ { "id": "XP_035295302", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295302", "type": "external" } ], "gene_names_uniprotkb": "Ube4b", "gene_names_refseq": "Ube4b", "protein_names_uniprotkb": "Ubiquitin conjugation factor E4; 2.3.2.27; RING-type E3 ubiquitin transferase E4", "protein_names_refseq": "ubiquitin conjugation factor E4 B isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100771525)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. Also functions as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. Mediates 'Lys-48'-linked polyubiquitination of substrates., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0034450 ubiquitin-ubiquitin ligase activity;GO:0005524 ATP binding;GO:0019899 enzyme binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000151 ubiquitin ligase complex", "go_biological_process": "GO:0000209 protein polyubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0036503 ERAD pathway;GO:0009411 response to UV;GO:0008626 granzyme-mediated apoptotic signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GMX7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GQA8-1", "uniprot_id": [ { "id": "A0A9J7GQA8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GQA8", "type": "external" } ], "mass": 366464.0, "length": 3333, "protein_name": "Laminin subunit alpha-3 isoform X2", "gene_name": "Lama3", "organism": "Hamster", "refseq_name": "laminin subunit alpha-3 isoform X2", "refseq_ac": [ { "id": "XP_035296167", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035296167", "type": "external" } ], "gene_names_uniprotkb": "Lama3", "gene_names_refseq": "Lama3", "protein_names_uniprotkb": "Laminin subunit alpha-3 isoform X2", "protein_names_refseq": "laminin subunit alpha-3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100755004)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0005201 extracellular matrix structural constituent", "go_cellular_component": "GO:0005576 extracellular region;GO:0030054 cell junction;GO:0005604 basement membrane;GO:0043256 laminin complex", "go_biological_process": "GO:0007155 cell adhesion;GO:0030155 regulation of cell adhesion;GO:0030334 regulation of cell migration;GO:0045995 regulation of embryonic development;GO:0009887 animal organ morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GQA8-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GFG6-1", "uniprot_id": [ { "id": "A0A9J7GFG6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GFG6", "type": "external" } ], "mass": 148786.0, "length": 1347, "protein_name": "C-Jun-amino-terminal kinase-interacting protein 3", "gene_name": "Mapk8ip3", "organism": "Hamster", "refseq_name": "C-Jun-amino-terminal kinase-interacting protein 3 isoform X1", "refseq_ac": [ { "id": "XP_027280785", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280785", "type": "external" } ], "gene_names_uniprotkb": "Mapk8ip3", "gene_names_refseq": "Mapk8ip3", "protein_names_uniprotkb": "C-Jun-amino-terminal kinase-interacting protein 3; JNK MAP kinase scaffold protein 3", "protein_names_refseq": "C-Jun-amino-terminal kinase-interacting protein 3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100750767)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031434 mitogen-activated protein kinase kinase binding;GO:0019894 kinesin binding;GO:0005078 MAP-kinase scaffold activity;GO:0016301 kinase activity;GO:0030159 signaling receptor complex adaptor activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0030425 dendrite;GO:0030426 growth cone;GO:0048471 perinuclear region of cytoplasm;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0099641 anterograde axonal protein transport;GO:0016192 vesicle-mediated transport;GO:0046328 regulation of JNK cascade", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GFG6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GF52-1", "uniprot_id": [ { "id": "A0A9J7GF52_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GF52", "type": "external" } ], "mass": 75177.0, "length": 656, "protein_name": "Poly(A)-specific ribonuclease PARN", "gene_name": "Parn", "organism": "Hamster", "refseq_name": "poly(A)-specific ribonuclease PARN isoform X1", "refseq_ac": [ { "id": "XP_007650658", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650658", "type": "external" } ], "gene_names_uniprotkb": "Parn", "gene_names_refseq": "Parn", "protein_names_uniprotkb": "Poly(A)-specific ribonuclease PARN; 3.1.13.4; Polyadenylate-specific ribonuclease", "protein_names_refseq": "poly(A)-specific ribonuclease PARN isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100771839)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613631.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0046872 metal ion binding;GO:0004535 poly(A)-specific ribonuclease activity;GO:0019901 protein kinase binding;GO:0070034 telomerase RNA binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005634 nucleus;GO:0016607 nuclear speck", "go_biological_process": "GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening;GO:1990431 priRNA 3'-end processing;GO:1990432 siRNA 3'-end processing;GO:0032212 positive regulation of telomere maintenance via telomerase", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GF52-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GFK8-1", "uniprot_id": [ { "id": "A0A9J7GFK8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GFK8", "type": "external" } ], "mass": 45544.0, "length": 398, "protein_name": "Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase", "gene_name": "Adprm", "organism": "Hamster", "refseq_name": "manganese-dependent ADP-ribose/CDP-alcohol diphosphatase isoform X3", "refseq_ac": [ { "id": "XP_027282923", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282923", "type": "external" } ], "gene_names_uniprotkb": "Adprm", "gene_names_refseq": "Adprm", "protein_names_uniprotkb": "Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase; 3.6.1.13; 3.6.1.16; 3.6.1.53; ADPRibase-Mn; CDP-choline phosphohydrolase", "protein_names_refseq": "manganese-dependent ADP-ribose/CDP-alcohol diphosphatase isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100767531)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other non-reducing ADP-sugars or CDP-glucose. May be involved in immune cell signaling as suggested by the second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.1.58", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.58", "type": "external" }, { "id": "3.6.1.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.13", "type": "external" }, { "id": "2.7.7.96", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.96", "type": "external" }, { "id": "3.6.1.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.16", "type": "external" }, { "id": "3.6.1.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.53", "type": "external" } ], "go_molecular_function": "GO:0030145 manganese ion binding;GO:0047631 ADP-ribose diphosphatase activity;GO:0047734 CDP-glycerol diphosphatase activity;GO:0008663 2',3'-cyclic-nucleotide 2'-phosphodiesterase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GFK8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GHV9-1", "uniprot_id": [ { "id": "A0A9J7GHV9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GHV9", "type": "external" } ], "mass": 90631.0, "length": 791, "protein_name": "Transient receptor potential cation channel subfamily V member 3", "gene_name": "Trpv3", "organism": "Hamster", "refseq_name": "transient receptor potential cation channel subfamily V member 3 isoform X1", "refseq_ac": [ { "id": "XP_027282597", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282597", "type": "external" } ], "gene_names_uniprotkb": "Trpv3", "gene_names_refseq": "Trpv3", "protein_names_uniprotkb": "Transient receptor potential cation channel subfamily V member 3", "protein_names_refseq": "transient receptor potential cation channel subfamily V member 3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100767987)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Non-selective calcium permeant cation channel. It is activated by innocuous (warm) temperatures and shows an increased response at noxious temperatures greater than 39 degrees Celsius. Activation exhibits an outward rectification. The channel pore can dilate to provide permeability to larger cations. May associate with TRPV1 and may modulate its activity. Is a negative regulator of hair growth and cycling: TRPV3-coupled signaling suppresses keratinocyte proliferation in hair follicles and induces apoptosis and premature hair follicle regression (catagen)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0005262 calcium channel activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005929 cilium;GO:0005764 lysosome", "go_biological_process": "GO:0007231 osmosensory signaling pathway;GO:0007015 actin filament organization;GO:0098703 calcium ion import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GHV9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GFA0-1", "uniprot_id": [ { "id": "A0A9J7GFA0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GFA0", "type": "external" } ], "mass": 167593.0, "length": 1470, "protein_name": "NACHT, LRR and PYD domains-containing protein 1a isoform X3", "gene_name": "LOC100756987", "organism": "Hamster", "refseq_name": "NACHT, LRR and PYD domains-containing protein 1a isoform X3", "refseq_ac": [ { "id": "XP_027282652", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282652", "type": "external" } ], "gene_names_uniprotkb": "LOC100756987", "gene_names_refseq": "LOC100756987", "protein_names_uniprotkb": "NACHT, LRR and PYD domains-containing protein 1a isoform X3", "protein_names_refseq": "NACHT, LRR and PYD domains-containing protein 1a isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100756987)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Constitutes the active part of the Nlrp1a inflammasome. In absence of pathogens and other damage-associated signals, interacts with the N-terminal part of Nlrp1a (NACHT, LRR and PYD domains-containing protein 1a, N-terminus), preventing activation of the Nlrp1a inflammasome. In response to pathogen-associated signals, the N-terminal part of Nlrp1a is degraded by the proteasome, releasing this form, which polymerizes to form the Nlrp1a inflammasome complex: the Nlrp1a inflammasome complex then directly recruits pro-caspase-1 (proCASP1) and promotes caspase-1 (CASP1) activation, leading to gasdermin-D (GSDMD) cleavage and subsequent pyroptosis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Constitutes the precursor of the Nlrp1a inflammasome, which mediates autoproteolytic processing within the FIIND domain to generate the N-terminal and C-terminal parts, which are associated non-covalently in absence of pathogens and other damage-associated signals., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008233 peptidase activity", "go_cellular_component": "GO:0061702 canonical inflammasome complex;GO:0005634 nucleus", "go_biological_process": "GO:0045087 innate immune response;GO:0006508 proteolysis;GO:0006954 inflammatory response;GO:0042981 regulation of apoptotic process;GO:0012501 programmed cell death", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GFA0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GFL2-1", "uniprot_id": [ { "id": "A0A9J7GFL2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GFL2", "type": "external" } ], "mass": 126768.0, "length": 1163, "protein_name": "Voltage-gated inwardly rectifying potassium channel KCNH2", "gene_name": "Kcnh2", "organism": "Hamster", "refseq_name": "potassium voltage-gated channel subfamily H member 2 isoform X2", "refseq_ac": [ { "id": "XP_027284260", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284260", "type": "external" } ], "gene_names_uniprotkb": "Kcnh2", "gene_names_refseq": "Kcnh2", "protein_names_uniprotkb": "Voltage-gated inwardly rectifying potassium channel KCNH2; Ether-a-go-go-related gene potassium channel 1; Potassium voltage-gated channel subfamily H member 2; Voltage-gated potassium channel subunit Kv11.1", "protein_names_refseq": "potassium voltage-gated channel subfamily H member 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100770245)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005242 inward rectifier potassium channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0034702 monoatomic ion channel complex", "go_biological_process": "GO:0086013 membrane repolarization during cardiac muscle cell action potential;GO:0086091 regulation of heart rate by cardiac conduction;GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GFL2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GG94-1", "uniprot_id": [ { "id": "A0A9J7GG94_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GG94", "type": "external" } ], "mass": 134999.0, "length": 1210, "protein_name": "phosphatidylinositol-3,5-bisphosphate 3-phosphatase", "gene_name": "Mtmr4", "organism": "Hamster", "refseq_name": "myotubularin-related protein 4 isoform X2", "refseq_ac": [ { "id": "XP_027282117", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282117", "type": "external" } ], "gene_names_uniprotkb": "Mtmr4", "gene_names_refseq": "Mtmr4", "protein_names_uniprotkb": "phosphatidylinositol-3,5-bisphosphate 3-phosphatase; 3.1.3.95; Phosphatidylinositol-3,5-bisphosphate 3-phosphatase; Phosphatidylinositol-3-phosphate phosphatase", "protein_names_refseq": "myotubularin-related protein 4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100753422)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0008270 zinc ion binding;GO:0004722 protein serine/threonine phosphatase activity;GO:0019903 protein phosphatase binding;GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0016020 membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0010506 regulation of autophagy;GO:0006661 phosphatidylinositol biosynthetic process;GO:0046856 phosphatidylinositol dephosphorylation;GO:0061952 midbody abscission", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GG94-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GFS3-1", "uniprot_id": [ { "id": "A0A9J7GFS3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GFS3", "type": "external" } ], "mass": 132641.0, "length": 1232, "protein_name": "AP2-associated protein kinase 1", "gene_name": "Aak1", "organism": "Hamster", "refseq_name": "AP2-associated protein kinase 1 isoform X1", "refseq_ac": [ { "id": "XP_007646778", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646778", "type": "external" } ], "gene_names_uniprotkb": "Aak1", "gene_names_refseq": "Aak1", "protein_names_uniprotkb": "AP2-associated protein kinase 1; 2.7.11.1; Adaptor-associated kinase 1", "protein_names_refseq": "AP2-associated protein kinase 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100771995)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 182 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614461.1) and transcript sequence (IACG01090528.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0035612 AP-2 adaptor complex binding", "go_cellular_component": "GO:0005905 clathrin-coated pit;GO:0098793 presynapse", "go_biological_process": "GO:0006897 endocytosis;GO:2000369 regulation of clathrin-dependent endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GFS3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GF20-1", "uniprot_id": [ { "id": "A0A9J7GF20_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GF20", "type": "external" } ], "mass": 40475.0, "length": 357, "protein_name": "Glucose-6-phosphatase", "gene_name": "G6pc", "organism": "Hamster", "refseq_name": "glucose-6-phosphatase", "refseq_ac": [ { "id": "XP_027283872", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283872", "type": "external" } ], "gene_names_uniprotkb": "G6pc", "gene_names_refseq": "G6pc", "protein_names_uniprotkb": "Glucose-6-phosphatase; 3.1.3.9", "protein_names_refseq": "glucose-6-phosphatase", "tax_id": 10029, "disease": "", "pathway": " (cge:100763214)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production in the terminal step of glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.9", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.9", "type": "external" }, { "id": "3.1.3.25", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.25", "type": "external" } ], "go_molecular_function": "GO:0004346 glucose-6-phosphatase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006094 gluconeogenesis;GO:0048878 chemical homeostasis;GO:0051156 glucose 6-phosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GF20-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GF22-1", "uniprot_id": [ { "id": "A0A9J7GF22_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GF22", "type": "external" } ], "mass": 140665.0, "length": 1321, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Aatk", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase LMTK1", "refseq_ac": [ { "id": "XP_007652147", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007652147", "type": "external" } ], "gene_names_uniprotkb": "Aatk", "gene_names_refseq": "Aatk", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase LMTK1", "tax_id": 10029, "disease": "", "pathway": " (cge:100753989)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613637.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0030425 dendrite;GO:0012505 endomembrane system", "go_biological_process": "GO:0007420 brain development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GF22-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GF37-1", "uniprot_id": [ { "id": "A0A9J7GF37_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GF37", "type": "external" } ], "mass": 55814.0, "length": 494, "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "Rad18", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase RAD18 isoform X1", "refseq_ac": [ { "id": "XP_003510826", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510826", "type": "external" } ], "gene_names_uniprotkb": "Rad18", "gene_names_refseq": "Rad18", "protein_names_uniprotkb": "RING-type E3 ubiquitin transferase; 2.3.2.27; RING-type E3 ubiquitin transferase RAD18", "protein_names_refseq": "E3 ubiquitin-protein ligase RAD18 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100758311)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614964.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0097505 Rad6-Rad18 complex", "go_biological_process": "GO:0006281 DNA repair;GO:0006301 DNA damage tolerance;GO:0006513 protein monoubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GF37-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GF59-1", "uniprot_id": [ { "id": "A0A9J7GF59_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GF59", "type": "external" } ], "mass": 85331.0, "length": 769, "protein_name": "Serine/threonine-protein kinase haspin", "gene_name": "LOC103160391", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase haspin", "refseq_ac": [ { "id": "XP_027282609", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282609", "type": "external" } ], "gene_names_uniprotkb": "LOC103160391", "gene_names_refseq": "LOC103160391", "protein_names_uniprotkb": "Serine/threonine-protein kinase haspin; 2.7.11.1; Germ cell-specific gene 2 protein; Haploid germ cell-specific nuclear protein kinase", "protein_names_refseq": "serine/threonine-protein kinase haspin", "tax_id": 10029, "disease": "", "pathway": " (cge:103160391)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. May act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0072354 histone H3T3 kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005819 spindle;GO:0005694 chromosome", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0035556 intracellular signal transduction;GO:1901991 negative regulation of mitotic cell cycle phase transition;GO:0051276 chromosome organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GF59-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GF88-1", "uniprot_id": [ { "id": "A0A9J7GF88_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GF88", "type": "external" } ], "mass": 78353.0, "length": 701, "protein_name": "ATP-dependent RNA helicase DHX33", "gene_name": "Dhx33", "organism": "Hamster", "refseq_name": "ATP-dependent RNA helicase DHX33 isoform X2", "refseq_ac": [ { "id": "XP_027282679", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282679", "type": "external" } ], "gene_names_uniprotkb": "Dhx33", "gene_names_refseq": "Dhx33", "protein_names_uniprotkb": "ATP-dependent RNA helicase DHX33; 3.6.4.13; DEAH box protein 33", "protein_names_refseq": "ATP-dependent RNA helicase DHX33 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100755235)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Implicated in nucleolar organization, ribosome biogenesis, protein synthesis and cytoplasmic dsRNA sensing. Stimulates RNA polymerase I transcription of the 47S precursor rRNA. Associates with ribosomal DNA (rDNA) loci where it is involved in POLR1A recruitment. In the cytoplasm, promotes elongation-competent 80S ribosome assembly at the late stage of mRNA translation initiation. Senses cytosolic dsRNA mediating NLRP3 inflammasome formation in macrophages and type I interferon production in myeloid dendritic cells. Required for NLRP3 activation induced by viral dsRNA and bacterial RNA. In dendritic cells, required for induction of type I interferon production induced by cytoplasmic dsRNA via the activation of MAPK and NF-kappa-B signaling pathways., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003725 double-stranded RNA binding;GO:0000182 rDNA binding;GO:0003724 RNA helicase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0061702 canonical inflammasome complex", "go_biological_process": "GO:0045943 positive regulation of transcription by RNA polymerase I", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GF88-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GF98-1", "uniprot_id": [ { "id": "A0A9J7GF98_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GF98", "type": "external" } ], "mass": 52227.0, "length": 480, "protein_name": "Beta-enolase", "gene_name": "Eno3", "organism": "Hamster", "refseq_name": "beta-enolase isoform X1", "refseq_ac": [ { "id": "XP_027282701", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282701", "type": "external" } ], "gene_names_uniprotkb": "Eno3", "gene_names_refseq": "Eno3", "protein_names_uniprotkb": "Beta-enolase; 2-phospho-D-glycerate hydro-lyase; 4.2.1.11; Enolase 3; Muscle-specific enolase; Skeletal muscle enolase", "protein_names_refseq": "beta-enolase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100771169)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Enolase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate in glycolysis and the reverse reaction in gluconeogenesis. Appears to have a function in striated muscle development and regeneration., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.2.1.11", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.11", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004634 phosphopyruvate hydratase activity", "go_cellular_component": "GO:0000015 phosphopyruvate hydratase complex;GO:0005886 plasma membrane", "go_biological_process": "GO:0006096 glycolytic process;GO:0061621 canonical glycolysis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GF98-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GFE8-1", "uniprot_id": [ { "id": "A0A9J7GFE8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GFE8", "type": "external" } ], "mass": 156029.0, "length": 1391, "protein_name": "Condensin complex subunit 1", "gene_name": "Ncapd2", "organism": "Hamster", "refseq_name": "condensin complex subunit 1", "refseq_ac": [ { "id": "XP_027284100", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284100", "type": "external" } ], "gene_names_uniprotkb": "Ncapd2", "gene_names_refseq": "Ncapd2", "protein_names_uniprotkb": "Condensin complex subunit 1", "protein_names_refseq": "condensin complex subunit 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100753087)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. May target the condensin complex to DNA via its C-terminal domain. May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Required for decatenation of non-centromeric ultrafine DNA bridges during anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042393 histone binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000796 condensin complex;GO:0000779 condensed chromosome, centromeric region", "go_biological_process": "GO:0051301 cell division;GO:0007076 mitotic chromosome condensation;GO:0010032 meiotic chromosome condensation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GFE8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GFG5-1", "uniprot_id": [ { "id": "A0A9J7GFG5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GFG5", "type": "external" } ], "mass": 69819.0, "length": 613, "protein_name": "Dynein axonemal intermediate chain 2", "gene_name": "Dnai2", "organism": "Hamster", "refseq_name": "dynein intermediate chain 2, axonemal", "refseq_ac": [ { "id": "XP_007641394", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641394", "type": "external" } ], "gene_names_uniprotkb": "Dnai2", "gene_names_refseq": "Dnai2", "protein_names_uniprotkb": "Dynein axonemal intermediate chain 2; Axonemal dynein intermediate chain 2", "protein_names_refseq": "dynein intermediate chain 2, axonemal", "tax_id": 10029, "disease": "", "pathway": " (cge:100761698)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of dynein, a family of motor proteins essential for movement along microtubules. Required for structural and functional integrity of cilia. Part of the dynein complex of respiratory cilia., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0045503 dynein light chain binding;GO:0045504 dynein heavy chain binding", "go_cellular_component": "GO:0005874 microtubule;GO:0036157 outer dynein arm;GO:0097729 9+2 motile cilium;GO:0120293 dynein axonemal particle", "go_biological_process": "GO:0003341 cilium movement;GO:0036158 outer dynein arm assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GFG5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GFK2-1", "uniprot_id": [ { "id": "A0A9J7GFK2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GFK2", "type": "external" } ], "mass": 95305.0, "length": 854, "protein_name": "Zinc phosphodiesterase ELAC protein 2", "gene_name": "Elac2", "organism": "Hamster", "refseq_name": "zinc phosphodiesterase ELAC protein 2 isoform X2", "refseq_ac": [ { "id": "XP_027282945", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282945", "type": "external" } ], "gene_names_uniprotkb": "Elac2", "gene_names_refseq": "Elac2", "protein_names_uniprotkb": "Zinc phosphodiesterase ELAC protein 2; 3.1.26.11; ElaC homolog protein 2; Ribonuclease Z 2; tRNA 3 endonuclease 2; tRNase Z 2", "protein_names_refseq": "zinc phosphodiesterase ELAC protein 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:107977006)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Zinc phosphodiesterase, which displays mitochondrial tRNA 3'-processing endonuclease activity. Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. Associates with mitochondrial DNA complexes at the nucleoids to initiate RNA processing and ribosome assembly., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0042781 3'-tRNA processing endoribonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0042645 mitochondrial nucleoid", "go_biological_process": "GO:1990180 mitochondrial tRNA 3'-end processing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GFK2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GFL3-1", "uniprot_id": [ { "id": "A0A9J7GFL3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GFL3", "type": "external" } ], "mass": 49916.0, "length": 439, "protein_name": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 7", "gene_name": "Enpp7", "organism": "Hamster", "refseq_name": "ectonucleotide pyrophosphatase/phosphodiesterase family member 7", "refseq_ac": [ { "id": "XP_003506746", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506746", "type": "external" } ], "gene_names_uniprotkb": "Enpp7", "gene_names_refseq": "Enpp7", "protein_names_uniprotkb": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 7; 3.1.4.12; Alkaline sphingomyelin phosphodiesterase; Intestinal alkaline sphingomyelinase", "protein_names_refseq": "ectonucleotide pyrophosphatase/phosphodiesterase family member 7", "tax_id": 10029, "disease": "", "pathway": " (cge:100755684)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614274.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.12", "type": "external" }, { "id": "3.1.4.38", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.38", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004767 sphingomyelin phosphodiesterase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GFL3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GFQ3-1", "uniprot_id": [ { "id": "A0A9J7GFQ3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GFQ3", "type": "external" } ], "mass": 211705.0, "length": 1925, "protein_name": "Plexin-D1", "gene_name": "Plxnd1", "organism": "Hamster", "refseq_name": "plexin-D1 isoform X2", "refseq_ac": [ { "id": "XP_027284992", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284992", "type": "external" } ], "gene_names_uniprotkb": "Plxnd1", "gene_names_refseq": "Plxnd1", "protein_names_uniprotkb": "Plexin-D1", "protein_names_refseq": "plexin-D1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100773048)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017154 semaphorin receptor activity", "go_cellular_component": "GO:0002116 semaphorin receptor complex;GO:0031258 lamellipodium membrane", "go_biological_process": "GO:0001525 angiogenesis;GO:0007162 negative regulation of cell adhesion;GO:0043542 endothelial cell migration;GO:0030334 regulation of cell migration;GO:0008360 regulation of cell shape", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GFQ3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GG68-1", "uniprot_id": [ { "id": "A0A9J7GG68_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GG68", "type": "external" } ], "mass": 20250.0, "length": 176, "protein_name": "Parathyroid hormone-related protein", "gene_name": "Pthlh", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: parathyroid hormone-related protein", "refseq_ac": [ { "id": "XP_003511955", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511955", "type": "external" } ], "gene_names_uniprotkb": "Pthlh", "gene_names_refseq": "Pthlh", "protein_names_uniprotkb": "Parathyroid hormone-related protein; PTH-rP; PTHrP", "protein_names_refseq": "LOW QUALITY PROTEIN: parathyroid hormone-related protein", "tax_id": 10029, "disease": "", "pathway": " (cge:100758030)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615266.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Dec 18, 2018 this sequence version replaced XP_003511955.2. COMPLETENESS: full length., [RefSeq]; Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. Up-regulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity of these cells to BMPs and allows them to respond to BMP4 in a paracrine and/or autocrine fashion. BMP4 signaling in the mesenchyme, in turn, triggers epithelial outgrowth and augments MSX2 expression, which causes the mammary mesenchyme to inhibit hair follicle formation within the nipple sheath., [UniProtKB, UniProtKB]; Potent inhibitor of osteoclastic bone resorption., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005179 hormone activity;GO:0051428 peptide hormone receptor binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0030282 bone mineralization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GG68-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GG74-1", "uniprot_id": [ { "id": "A0A9J7GG74_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GG74", "type": "external" } ], "mass": 67137.0, "length": 589, "protein_name": "Cyclin-dependent kinase-like 3", "gene_name": "Cdkl3", "organism": "Hamster", "refseq_name": "cyclin-dependent kinase-like 3 isoform X1", "refseq_ac": [ { "id": "XP_027283366", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283366", "type": "external" } ], "gene_names_uniprotkb": "Cdkl3", "gene_names_refseq": "Cdkl3", "protein_names_uniprotkb": "Cyclin-dependent kinase-like 3; 2.7.11.22", "protein_names_refseq": "cyclin-dependent kinase-like 3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100757962)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004693 cyclin-dependent protein serine/threonine kinase activity;GO:0004674 protein serine/threonine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0050775 positive regulation of dendrite morphogenesis;GO:0097484 dendrite extension;GO:0030517 negative regulation of axon extension", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GG74-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GGA1-1", "uniprot_id": [ { "id": "A0A9J7GGA1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GGA1", "type": "external" } ], "mass": 31206.0, "length": 318, "protein_name": "E3 ubiquitin-protein ligase ZNRF2", "gene_name": "Znrf2", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase ZNRF2 isoform X2", "refseq_ac": [ { "id": "XP_027285473", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285473", "type": "external" } ], "gene_names_uniprotkb": "Znrf2", "gene_names_refseq": "Znrf2", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase ZNRF2; 2.3.2.27; RING-type E3 ubiquitin transferase ZNRF2; Zinc/RING finger protein 2", "protein_names_refseq": "LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase ZNRF2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100760215)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 2 indels ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005768 endosome;GO:0005764 lysosome;GO:0042734 presynaptic membrane", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0070936 protein K48-linked ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GGA1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GGL5-1", "uniprot_id": [ { "id": "A0A9J7GGL5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GGL5", "type": "external" } ], "mass": 116865.0, "length": 1051, "protein_name": "Ankyrin repeat domain-containing protein 27", "gene_name": "Ankrd27", "organism": "Hamster", "refseq_name": "ankyrin repeat domain-containing protein 27 isoform X2", "refseq_ac": [ { "id": "XP_027286092", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286092", "type": "external" } ], "gene_names_uniprotkb": "Ankrd27; LOC118239822", "gene_names_refseq": "Ankrd27", "protein_names_uniprotkb": "Ankyrin repeat domain-containing protein 27", "protein_names_refseq": "ankyrin repeat domain-containing protein 27 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100758465); (cge:118239822)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity;GO:0031267 small GTPase binding;GO:0000149 SNARE binding", "go_cellular_component": "GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0005764 lysosome;GO:0030659 cytoplasmic vesicle membrane;GO:0042470 melanosome", "go_biological_process": "GO:0015031 protein transport;GO:0048812 neuron projection morphogenesis;GO:0045022 early endosome to late endosome transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GGL5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GGG5-1", "uniprot_id": [ { "id": "A0A9J7GGG5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GGG5", "type": "external" } ], "mass": 115633.0, "length": 1050, "protein_name": "C2 domain-containing protein 5", "gene_name": "C2cd5", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: C2 domain-containing protein 5 isoform X3", "refseq_ac": [ { "id": "XP_027285958", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285958", "type": "external" } ], "gene_names_uniprotkb": "C2cd5", "gene_names_refseq": "C2cd5", "protein_names_uniprotkb": "C2 domain-containing protein 5", "protein_names_refseq": "LOW QUALITY PROTEIN: C2 domain-containing protein 5 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100766087)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Required for insulin-stimulated glucose transport and glucose transporter SLC2A4/GLUT4 translocation from intracellular glucose storage vesicle (GSV) to the plasma membrane (PM) in adipocytes. Binds phospholipid membranes in a calcium-dependent manner and is necessary for the optimal membrane fusion between SLC2A4/GLUT4 GSV and the PM., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0005544 calcium-dependent phospholipid binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0030659 cytoplasmic vesicle membrane;GO:0001726 ruffle", "go_biological_process": "GO:0072659 protein localization to plasma membrane;GO:0008286 insulin receptor signaling pathway;GO:0031340 positive regulation of vesicle fusion;GO:0065002 intracellular protein transmembrane transport;GO:0090314 positive regulation of protein targeting to membrane", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GGG5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GGI6-1", "uniprot_id": [ { "id": "A0A9J7GGI6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GGI6", "type": "external" } ], "mass": 56040.0, "length": 491, "protein_name": "Cytochrome P450", "gene_name": "LOC100765441", "organism": "Hamster", "refseq_name": "cytochrome P450 2B1", "refseq_ac": [ { "id": "XP_027286206", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286206", "type": "external" } ], "gene_names_uniprotkb": "LOC100765441", "gene_names_refseq": "LOC100765441", "protein_names_uniprotkb": "Cytochrome P450; 1.14.14.1", "protein_names_refseq": "cytochrome P450 2B1", "tax_id": 10029, "disease": "", "pathway": " (cge:100765441)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.14.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.-", "type": "external" }, { "id": "1.14.14.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.1", "type": "external" }, { "id": "1.14.13.n7", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.n7", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0008392 arachidonate epoxygenase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006805 xenobiotic metabolic process;GO:0019373 epoxygenase P450 pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GGI6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GGM9-1", "uniprot_id": [ { "id": "A0A9J7GGM9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GGM9", "type": "external" } ], "mass": 70625.0, "length": 624, "protein_name": "Transporter", "gene_name": "Slc6a12", "organism": "Hamster", "refseq_name": "sodium- and chloride-dependent betaine transporter isoform X1", "refseq_ac": [ { "id": "XP_027285147", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285147", "type": "external" } ], "gene_names_uniprotkb": "Slc6a12", "gene_names_refseq": "Slc6a12", "protein_names_uniprotkb": "Transporter", "protein_names_refseq": "sodium- and chloride-dependent betaine transporter isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100752445)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Transporter that mediates cellular uptake of betaine and GABA in a sodium- and chloride-dependent process. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation. Probably also involved in renal and hepatic osmotic regulation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005332 gamma-aminobutyric acid:sodium:chloride symporter activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0016323 basolateral plasma membrane;GO:0042995 cell projection", "go_biological_process": "GO:0006836 neurotransmitter transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GGM9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GGP1-1", "uniprot_id": [ { "id": "A0A9J7GGP1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GGP1", "type": "external" } ], "mass": 91058.0, "length": 828, "protein_name": "Mitogen-activated protein kinase kinase kinase kinase", "gene_name": "Map4k1", "organism": "Hamster", "refseq_name": "mitogen-activated protein kinase kinase kinase kinase 1 isoform X2", "refseq_ac": [ { "id": "XP_027286333", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286333", "type": "external" } ], "gene_names_uniprotkb": "Map4k1", "gene_names_refseq": "Map4k1", "protein_names_uniprotkb": "Mitogen-activated protein kinase kinase kinase kinase; 2.7.11.1", "protein_names_refseq": "mitogen-activated protein kinase kinase kinase kinase 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100766308)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Serine/threonine kinase that plays a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008349 MAP kinase kinase kinase kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GGP1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GGR5-1", "uniprot_id": [ { "id": "A0A9J7GGR5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GGR5", "type": "external" } ], "mass": 56327.0, "length": 491, "protein_name": "Cytochrome P450", "gene_name": "LOC100763652", "organism": "Hamster", "refseq_name": "cytochrome P450 2B1 isoform X2", "refseq_ac": [ { "id": "XP_027286205", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286205", "type": "external" } ], "gene_names_uniprotkb": "LOC100763652", "gene_names_refseq": "LOC100763652", "protein_names_uniprotkb": "Cytochrome P450; 1.14.14.1", "protein_names_refseq": "cytochrome P450 2B1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763652)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.14.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.-", "type": "external" }, { "id": "1.14.14.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.1", "type": "external" }, { "id": "1.14.13.n7", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.n7", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0008392 arachidonate epoxygenase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006805 xenobiotic metabolic process;GO:0019373 epoxygenase P450 pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GGR5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GGT1-1", "uniprot_id": [ { "id": "A0A9J7GGT1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GGT1", "type": "external" } ], "mass": 33831.0, "length": 304, "protein_name": "Adapter molecule crk", "gene_name": "Crk", "organism": "Hamster", "refseq_name": "adapter molecule crk isoform X2", "refseq_ac": [ { "id": "XP_027282531", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282531", "type": "external" } ], "gene_names_uniprotkb": "Crk", "gene_names_refseq": "Crk", "protein_names_uniprotkb": "Adapter molecule crk; Proto-oncogene c-Crk; p38", "protein_names_refseq": "adapter molecule crk isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762827)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in cell branching and adhesion mediated by BCAR1-CRK-RAPGEF1 signaling and activation of RAP1., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030971 receptor tyrosine kinase binding;GO:0035591 signaling adaptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0016477 cell migration;GO:0002682 regulation of immune system process;GO:0030334 regulation of cell migration;GO:0035020 regulation of Rac protein signal transduction;GO:1902533 positive regulation of intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GGT1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GGT4-1", "uniprot_id": [ { "id": "A0A9J7GGT4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GGT4", "type": "external" } ], "mass": 84012.0, "length": 757, "protein_name": "Amine oxidase", "gene_name": "Aoc2", "organism": "Hamster", "refseq_name": "retina-specific copper amine oxidase isoform X2", "refseq_ac": [ { "id": "XP_027283861", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283861", "type": "external" } ], "gene_names_uniprotkb": "Aoc2", "gene_names_refseq": "Aoc2", "protein_names_uniprotkb": "Amine oxidase; 1.4.3.-", "protein_names_refseq": "retina-specific copper amine oxidase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762635)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.4.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.-", "type": "external" } ], "go_molecular_function": "GO:0005507 copper ion binding;GO:0008131 primary methylamine oxidase activity;GO:0048038 quinone binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0009308 amine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GGT4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GJJ1-1", "uniprot_id": [ { "id": "A0A9J7GJJ1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GJJ1", "type": "external" } ], "mass": 297500.0, "length": 2790, "protein_name": "Multiple epidermal growth factor-like domains protein 8", "gene_name": "Megf8", "organism": "Hamster", "refseq_name": "multiple epidermal growth factor-like domains protein 8 isoform X2", "refseq_ac": [ { "id": "XP_027286131", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286131", "type": "external" } ], "gene_names_uniprotkb": "Megf8", "gene_names_refseq": "Megf8", "protein_names_uniprotkb": "Multiple epidermal growth factor-like domains protein 8; Epidermal growth factor-like protein 4", "protein_names_refseq": "multiple epidermal growth factor-like domains protein 8 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100755592)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Acts as a negative regulator of hedgehog signaling., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0048598 embryonic morphogenesis;GO:0048705 skeletal system morphogenesis;GO:0035108 limb morphogenesis;GO:0002009 morphogenesis of an epithelium;GO:0061371 determination of heart left/right asymmetry", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GJJ1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GH40-1", "uniprot_id": [ { "id": "A0A9J7GH40_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GH40", "type": "external" } ], "mass": 58294.0, "length": 527, "protein_name": "Lymphocyte activation gene 3 protein", "gene_name": "Lag3", "organism": "Hamster", "refseq_name": "lymphocyte activation gene 3 protein", "refseq_ac": [ { "id": "XP_003496108", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496108", "type": "external" } ], "gene_names_uniprotkb": "Lag3", "gene_names_refseq": "Lag3", "protein_names_uniprotkb": "Lymphocyte activation gene 3 protein", "protein_names_refseq": "lymphocyte activation gene 3 protein", "tax_id": 10029, "disease": "", "pathway": " (cge:100756493)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613610.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May function as a ligand for MHC class II (MHC-II) on antigen-presenting cells (APC), promoting APC activation/maturation and driving Th1 immune response., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042289 MHC class II protein binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane", "go_biological_process": "GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GH40-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GHB1-1", "uniprot_id": [ { "id": "A0A9J7GHB1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GHB1", "type": "external" } ], "mass": 78369.0, "length": 731, "protein_name": "Heat shock factor protein 5", "gene_name": "Hsf5", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: heat shock factor protein 5 isoform X2", "refseq_ac": [ { "id": "XP_027282129", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282129", "type": "external" } ], "gene_names_uniprotkb": "Hsf5", "gene_names_refseq": "Hsf5", "protein_names_uniprotkb": "Heat shock factor protein 5; Heat shock transcription factor 5", "protein_names_refseq": "LOW QUALITY PROTEIN: heat shock factor protein 5 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100758083)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 2 indels ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; DNA-binding transcription factor that is essential for male fertility, spermatogenesis and meiotic prophase progression in spermatocytes under non-stress conditions. Positvely and negatively regulates gene expression to ensure progression of meiotic prophase beyond pachytene stage in spermatocytes., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0051321 meiotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GHB1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GHB3-1", "uniprot_id": [ { "id": "A0A9J7GHB3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GHB3", "type": "external" } ], "mass": 45887.0, "length": 408, "protein_name": "Dual specificity mitogen-activated protein kinase kinase 4", "gene_name": "Map2k4", "organism": "Hamster", "refseq_name": "dual specificity mitogen-activated protein kinase kinase 4 isoform X2", "refseq_ac": [ { "id": "XP_027282942", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282942", "type": "external" } ], "gene_names_uniprotkb": "Map2k4", "gene_names_refseq": "Map2k4", "protein_names_uniprotkb": "Dual specificity mitogen-activated protein kinase kinase 4; 2.7.12.2; JNK-activating kinase 1; MAPK/ERK kinase 4; SAPK/ERK kinase 1", "protein_names_refseq": "dual specificity mitogen-activated protein kinase kinase 4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100770977)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0008545 JUN kinase kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0033554 cellular response to stress", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GHB3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GHD4-1", "uniprot_id": [ { "id": "A0A9J7GHD4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GHD4", "type": "external" } ], "mass": 53385.0, "length": 474, "protein_name": "Leukocyte receptor cluster member 4", "gene_name": "Mboat7", "organism": "Hamster", "refseq_name": "lysophospholipid acyltransferase 7 isoform X2", "refseq_ac": [ { "id": "XP_027286804", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286804", "type": "external" } ], "gene_names_uniprotkb": "Mboat7", "gene_names_refseq": "Mboat7", "protein_names_uniprotkb": "Leukocyte receptor cluster member 4; Lysophospholipid acyltransferase 7; Membrane-bound O-acyltransferase domain-containing protein 7", "protein_names_refseq": "lysophospholipid acyltransferase 7 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100766440)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0071617 lysophospholipid acyltransferase activity;GO:0008374 O-acyltransferase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0044233 mitochondria-associated endoplasmic reticulum membrane contact site", "go_biological_process": "GO:0006661 phosphatidylinositol biosynthetic process;GO:0030258 lipid modification", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GHD4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GHG3-1", "uniprot_id": [ { "id": "A0A9J7GHG3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GHG3", "type": "external" } ], "mass": 140492.0, "length": 1318, "protein_name": "Rho GTPase-activating protein 33", "gene_name": "Arhgap33", "organism": "Hamster", "refseq_name": "rho GTPase-activating protein 33 isoform X2", "refseq_ac": [ { "id": "XP_027287060", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287060", "type": "external" } ], "gene_names_uniprotkb": "Arhgap33", "gene_names_refseq": "Arhgap33", "protein_names_uniprotkb": "Rho GTPase-activating protein 33; Rho-type GTPase-activating protein 33; Sorting nexin-26; Tc10/CDC42 GTPase-activating protein", "protein_names_refseq": "rho GTPase-activating protein 33 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774198)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in several stages of intracellular trafficking. Could play an important role in the regulation of glucose transport by insulin. May act as a downstream effector of RHOQ/TC10 in the regulation of insulin-stimulated glucose transport., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0035091 phosphatidylinositol binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0015629 actin cytoskeleton", "go_biological_process": "GO:0015031 protein transport;GO:0007264 small GTPase-mediated signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GHG3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GHH7-1", "uniprot_id": [ { "id": "A0A9J7GHH7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GHH7", "type": "external" } ], "mass": 114096.0, "length": 1034, "protein_name": "Sodium/potassium-transporting ATPase subunit alpha", "gene_name": "Atp4a", "organism": "Hamster", "refseq_name": "potassium-transporting ATPase alpha chain 1 isoform X1", "refseq_ac": [ { "id": "XP_027286884", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286884", "type": "external" } ], "gene_names_uniprotkb": "Atp4a", "gene_names_refseq": "Atp4a", "protein_names_uniprotkb": "Sodium/potassium-transporting ATPase subunit alpha", "protein_names_refseq": "potassium-transporting ATPase alpha chain 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100767384)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; The catalytic subunit of the gastric H(+)/K(+) ATPase pump which transports H(+) ions in exchange for K(+) ions across the apical membrane of parietal cells. Uses ATP as an energy source to pump H(+) ions to the gastric lumen while transporting K(+) ion from the lumen into the cell. Remarkably generates a million-fold proton gradient across the gastric parietal cell membrane, acidifying the gastric juice down to pH 1. Within a transport cycle, the transfer of a H(+) ion across the membrane is coupled to ATP hydrolysis and is associated with a transient phosphorylation that shifts the pump conformation from inward-facing (E1) to outward-facing state (E2). The release of the H(+) ion in the stomach lumen is followed by binding of K(+) ion converting the pump conformation back to the E1 state., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "7.2.2.19", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.19", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0005391 P-type sodium:potassium-exchanging transporter activity;GO:0008900 P-type potassium:proton transporter activity", "go_cellular_component": "GO:0016324 apical plasma membrane", "go_biological_process": "GO:0006883 intracellular sodium ion homeostasis;GO:0030007 intracellular potassium ion homeostasis;GO:0036376 sodium ion export across plasma membrane;GO:1990573 potassium ion import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GHH7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GHK8-1", "uniprot_id": [ { "id": "A0A9J7GHK8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GHK8", "type": "external" } ], "mass": 18296.0, "length": 165, "protein_name": "Growth arrest and DNA damage-inducible protein GADD45 alpha", "gene_name": "Gadd45a", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Gadd45a", "gene_names_refseq": "", "protein_names_uniprotkb": "Growth arrest and DNA damage-inducible protein GADD45 alpha", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": " (cge:103159266)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0019900 kinase binding;GO:1990841 promoter-specific chromatin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016607 nuclear speck", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0043065 positive regulation of apoptotic process;GO:0046330 positive regulation of JNK cascade;GO:0042770 signal transduction in response to DNA damage;GO:0043537 negative regulation of blood vessel endothelial cell migration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GHK8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GHP7-1", "uniprot_id": [ { "id": "A0A9J7GHP7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GHP7", "type": "external" } ], "mass": 42895.0, "length": 385, "protein_name": "Branched-chain-amino-acid aminotransferase", "gene_name": "Bcat1", "organism": "Hamster", "refseq_name": "branched-chain-amino-acid aminotransferase, cytosolic isoform X2", "refseq_ac": [ { "id": "XP_027285947", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285947", "type": "external" } ], "gene_names_uniprotkb": "Bcat1", "gene_names_refseq": "Bcat1", "protein_names_uniprotkb": "Branched-chain-amino-acid aminotransferase; 2.6.1.42", "protein_names_refseq": "branched-chain-amino-acid aminotransferase, cytosolic isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763658)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.6.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.42", "type": "external" } ], "go_molecular_function": "GO:0004084 branched-chain-amino-acid transaminase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0009098 L-leucine biosynthetic process;GO:0009099 L-valine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GHP7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GHR4-1", "uniprot_id": [ { "id": "A0A9J7GHR4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GHR4", "type": "external" } ], "mass": 86752.0, "length": 760, "protein_name": "General transcription and DNA repair factor IIH helicase subunit XPD", "gene_name": "Ercc2", "organism": "Hamster", "refseq_name": "general transcription and DNA repair factor IIH helicase subunit XPD isoform X2", "refseq_ac": [ { "id": "XP_027286709", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286709", "type": "external" } ], "gene_names_uniprotkb": "Ercc2", "gene_names_refseq": "Ercc2", "protein_names_uniprotkb": "General transcription and DNA repair factor IIH helicase subunit XPD; 5.6.2.3; CXPD; DNA 5'-3' helicase XPD; DNA excision repair protein ERCC-2; DNA repair protein complementing XP-D cells; Xeroderma pigmentosum group D-complementing protein", "protein_names_refseq": "general transcription and DNA repair factor IIH helicase subunit XPD isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100689272)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0003684 damaged DNA binding;GO:0043139 5'-3' DNA helicase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0007059 chromosome segregation;GO:0006366 transcription by RNA polymerase II;GO:0006289 nucleotide-excision repair;GO:0035315 hair cell differentiation;GO:0045951 positive regulation of mitotic recombination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GHR4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GHU0-1", "uniprot_id": [ { "id": "A0A9J7GHU0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GHU0", "type": "external" } ], "mass": 56503.0, "length": 493, "protein_name": "Cytochrome P450", "gene_name": "LOC100759787", "organism": "Hamster", "refseq_name": "cytochrome P450 2B1 isoform X2", "refseq_ac": [ { "id": "XP_027286204", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286204", "type": "external" } ], "gene_names_uniprotkb": "LOC100759787", "gene_names_refseq": "LOC100759787", "protein_names_uniprotkb": "Cytochrome P450; 1.14.14.1", "protein_names_refseq": "cytochrome P450 2B1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100759787)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.14.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.-", "type": "external" }, { "id": "1.14.14.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.1", "type": "external" }, { "id": "1.14.13.n7", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.n7", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0008392 arachidonate epoxygenase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006805 xenobiotic metabolic process;GO:0019373 epoxygenase P450 pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GHU0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GHU8-1", "uniprot_id": [ { "id": "A0A9J7GHU8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GHU8", "type": "external" } ], "mass": 213111.0, "length": 1912, "protein_name": "Plexin-A1", "gene_name": "Plxna1", "organism": "Hamster", "refseq_name": "plexin-A1", "refseq_ac": [ { "id": "XP_003495204", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495204", "type": "external" } ], "gene_names_uniprotkb": "Plxna1", "gene_names_refseq": "Plxna1", "protein_names_uniprotkb": "Plexin-A1", "protein_names_refseq": "plexin-A1", "tax_id": 10029, "disease": "", "pathway": " (cge:100760933)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613584.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. Acts as coreceptor of TREM2 for SEMA6D in dendritic cells and is involved in the generation of immune responses and skeletal homeostasis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017154 semaphorin receptor activity", "go_cellular_component": "GO:0002116 semaphorin receptor complex;GO:0005886 plasma membrane", "go_biological_process": "GO:0060429 epithelium development;GO:0030900 forebrain development;GO:0030334 regulation of cell migration;GO:0021954 central nervous system neuron development;GO:0021602 cranial nerve morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GHU8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GM40-1", "uniprot_id": [ { "id": "A0A9J7GM40_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GM40", "type": "external" } ], "mass": 59610.0, "length": 535, "protein_name": "Protein NNX3", "gene_name": "Uri1", "organism": "Hamster", "refseq_name": "unconventional prefoldin RPB5 interactor 1 isoform X2", "refseq_ac": [ { "id": "XP_027286105", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286105", "type": "external" } ], "gene_names_uniprotkb": "Uri1", "gene_names_refseq": "Uri1", "protein_names_uniprotkb": "Protein NNX3; Protein phosphatase 1 regulatory subunit 19; RNA polymerase II subunit 5-mediating protein", "protein_names_refseq": "unconventional prefoldin RPB5 interactor 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100753065)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays a central role in maintaining S6K1 signaling and BAD phosphorylation under normal growth conditions thereby protecting cells from potential deleterious effects of sustained S6K1 signaling. The URI1-PPP1CC complex acts as a central component of a negative feedback mechanism that counteracts excessive S6K1 survival signaling to BAD in response to growth factors. Mediates inhibition of PPP1CC phosphatase activity in mitochondria. Coordinates the regulation of nutrient-sensitive gene expression availability in a mTOR-dependent manner. Seems to be a scaffolding protein able to assemble a prefoldin-like complex that contains PFDs and proteins with roles in transcription and ubiquitination., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0003714 transcription corepressor activity;GO:0019212 phosphatase inhibitor activity;GO:0004864 protein phosphatase inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0030425 dendrite", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GM40-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GHW1-1", "uniprot_id": [ { "id": "A0A9J7GHW1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GHW1", "type": "external" } ], "mass": 30467.0, "length": 276, "protein_name": "Platelet-activating factor acetylhydrolase IB subunit alpha1", "gene_name": "Pafah1b3", "organism": "Hamster", "refseq_name": "platelet-activating factor acetylhydrolase IB subunit gamma isoform X2", "refseq_ac": [ { "id": "XP_027286135", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286135", "type": "external" } ], "gene_names_uniprotkb": "Pafah1b3", "gene_names_refseq": "Pafah1b3", "protein_names_uniprotkb": "Platelet-activating factor acetylhydrolase IB subunit alpha1; 3.1.1.47; PAF acetylhydrolase 29 kDa subunit; PAF-AH subunit gamma", "protein_names_refseq": "platelet-activating factor acetylhydrolase IB subunit gamma isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756174)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Alpha1 catalytic subunit of the cytosolic type I platelet-activating factor (PAF) acetylhydrolase (PAF-AH (I)) heterotetrameric enzyme that catalyzes the hydrolyze of the acetyl group at the sn-2 position of PAF and its analogs and modulates the action of PAF. The activity and substrate specificity of PAF-AH (I) are affected by its subunit composition. Both alpha1/alpha1 homodimer (PAFAH1B3/PAFAH1B3 homodimer) and alpha1/alpha2 heterodimer(PAFAH1B3/PAFAH1B2 heterodimer) hydrolyze 1-O-alkyl-2-acetyl-sn-glycero-3-phosphoric acid (AAGPA) more efficiently than PAF, but they have little hydrolytic activity towards 1-O-alkyl-2-acetyl-sn-glycero-3-phosphorylethanolamine (AAGPE). Plays an important role during the development of brain., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "3.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32", "type": "external" }, { "id": "3.1.1.47", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.47", "type": "external" } ], "go_molecular_function": "GO:0047179 platelet-activating factor acetyltransferase activity;GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity;GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0016042 lipid catabolic process;GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GHW1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GHX1-1", "uniprot_id": [ { "id": "A0A9J7GHX1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GHX1", "type": "external" } ], "mass": 109305.0, "length": 980, "protein_name": "Glutamate receptor", "gene_name": "Grik5", "organism": "Hamster", "refseq_name": "glutamate receptor ionotropic, kainate 5 isoform X2", "refseq_ac": [ { "id": "XP_027286157", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286157", "type": "external" } ], "gene_names_uniprotkb": "Grik5", "gene_names_refseq": "Grik5", "protein_names_uniprotkb": "Glutamate receptor", "protein_names_refseq": "glutamate receptor ionotropic, kainate 5 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100757915)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity;GO:0038023 signaling receptor activity;GO:0015277 kainate selective glutamate receptor activity;GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential;GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential", "go_cellular_component": "GO:0045211 postsynaptic membrane;GO:0042734 presynaptic membrane;GO:0005783 endoplasmic reticulum;GO:0032983 kainate selective glutamate receptor complex;GO:0098839 postsynaptic density membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GHX1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GHX4-1", "uniprot_id": [ { "id": "A0A9J7GHX4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GHX4", "type": "external" } ], "mass": 44326.0, "length": 399, "protein_name": "C5a anaphylatoxin chemotactic receptor 1", "gene_name": "LOC113837324", "organism": "Hamster", "refseq_name": "C5a anaphylatoxin chemotactic receptor 1-like", "refseq_ac": [ { "id": "XP_027286828", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286828", "type": "external" } ], "gene_names_uniprotkb": "LOC113837324", "gene_names_refseq": "LOC113837324", "protein_names_uniprotkb": "C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin chemotactic receptor", "protein_names_refseq": "C5a anaphylatoxin chemotactic receptor 1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113837324)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a, stimulating chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. C5AR1 is coupled to G(i)/G(o) (GNAI1 or GNAO1) G alpha proteins and mediates inhibition of adenylate cyclase. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004878 complement component C5a receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0006935 chemotaxis;GO:0006954 inflammatory response;GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GHX4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GJE9-1", "uniprot_id": [ { "id": "A0A9J7GJE9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GJE9", "type": "external" } ], "mass": 214633.0, "length": 1892, "protein_name": "Transcription initiation factor TFIID subunit", "gene_name": "Taf1", "organism": "Hamster", "refseq_name": "transcription initiation factor TFIID subunit 1 isoform X3", "refseq_ac": [ { "id": "XP_027287573", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287573", "type": "external" } ], "gene_names_uniprotkb": "Taf1", "gene_names_refseq": "Taf1", "protein_names_uniprotkb": "Transcription initiation factor TFIID subunit", "protein_names_refseq": "transcription initiation factor TFIID subunit 1 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100751131)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "2.3.1.259", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.259", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0004674 protein serine/threonine kinase activity;GO:0017025 TBP-class protein binding;GO:0004402 histone acetyltransferase activity;GO:0016251 RNA polymerase II general transcription initiation factor activity", "go_cellular_component": "GO:0005669 transcription factor TFIID complex", "go_biological_process": "GO:0051123 RNA polymerase II preinitiation complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GJE9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GI12-1", "uniprot_id": [ { "id": "A0A9J7GI12_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GI12", "type": "external" } ], "mass": 45247.0, "length": 404, "protein_name": "Cytochrome P450", "gene_name": "LOC100772193", "organism": "Hamster", "refseq_name": "cytochrome P450 2S1 isoform X2", "refseq_ac": [ { "id": "XP_027286200", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286200", "type": "external" } ], "gene_names_uniprotkb": "LOC100772193", "gene_names_refseq": "LOC100772193", "protein_names_uniprotkb": "Cytochrome P450; 1.14.14.1", "protein_names_refseq": "cytochrome P450 2S1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772193)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cytochromes P450 are a group of heme-thiolate monooxygenases., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.14.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.-", "type": "external" }, { "id": "1.14.14.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.1", "type": "external" }, { "id": "1.14.13.n7", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.n7", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0008392 arachidonate epoxygenase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006805 xenobiotic metabolic process;GO:0019373 epoxygenase P450 pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GI12-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GI33-1", "uniprot_id": [ { "id": "A0A9J7GI33_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GI33", "type": "external" } ], "mass": 103274.0, "length": 941, "protein_name": "Mitogen-activated protein kinase kinase kinase", "gene_name": "Map3k10", "organism": "Hamster", "refseq_name": "mitogen-activated protein kinase kinase kinase 10 isoform X2", "refseq_ac": [ { "id": "XP_027286259", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286259", "type": "external" } ], "gene_names_uniprotkb": "Map3k10", "gene_names_refseq": "Map3k10", "protein_names_uniprotkb": "Mitogen-activated protein kinase kinase kinase; 2.7.11.25", "protein_names_refseq": "mitogen-activated protein kinase kinase kinase 10 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100768062)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004706 JUN kinase kinase kinase activity", "go_cellular_component": "", "go_biological_process": "GO:0043065 positive regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GI33-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GI74-1", "uniprot_id": [ { "id": "A0A9J7GI74_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GI74", "type": "external" } ], "mass": 139547.0, "length": 1231, "protein_name": "Kinesin motor domain-containing protein", "gene_name": "Kif4a", "organism": "Hamster", "refseq_name": "chromosome-associated kinesin KIF4A", "refseq_ac": [ { "id": "XP_027287527", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287527", "type": "external" } ], "gene_names_uniprotkb": "Kif4a", "gene_names_refseq": "Kif4a", "protein_names_uniprotkb": "Kinesin motor domain-containing protein", "protein_names_refseq": "chromosome-associated kinesin KIF4A", "tax_id": 10029, "disease": "", "pathway": " (cge:100769995)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0046872 metal ion binding;GO:0003777 microtubule motor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005874 microtubule;GO:0005875 microtubule associated complex", "go_biological_process": "GO:0007018 microtubule-based movement;GO:0007052 mitotic spindle organization;GO:0051231 spindle elongation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GI74-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GIC4-1", "uniprot_id": [ { "id": "A0A9J7GIC4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GIC4", "type": "external" } ], "mass": 71984.0, "length": 648, "protein_name": "Serine/threonine-protein kinase 26", "gene_name": "Stk26", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase 26 isoform X2", "refseq_ac": [ { "id": "XP_027287871", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287871", "type": "external" } ], "gene_names_uniprotkb": "Stk26", "gene_names_refseq": "Stk26", "protein_names_uniprotkb": "Serine/threonine-protein kinase 26; 2.7.11.1; Mammalian STE20-like protein kinase 4", "protein_names_refseq": "serine/threonine-protein kinase 26 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762146)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 38% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027287871.1. COMPLETENESS: full length., [RefSeq]; Serine/threonine-protein kinase that acts as a mediator of cell growth. Modulates apoptosis. In association with STK24 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation. Phosphorylates ATG4B at 'Ser-383', thereby increasing autophagic flux. Part of the striatin-interacting phosphatase and kinase (STRIPAK) complexes. STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytoskeleton remodeling. Different types of STRIPAK complexes are involved in a variety of biological processes such as cell growth, differentiation, apoptosis, metabolism and immune regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005794 Golgi apparatus", "go_biological_process": "GO:0006915 apoptotic process;GO:0030336 negative regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GIC4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GID0-1", "uniprot_id": [ { "id": "A0A9J7GID0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GID0", "type": "external" } ], "mass": 140948.0, "length": 1232, "protein_name": "ATP-dependent RNA helicase DHX8", "gene_name": "LOC103158905", "organism": "Hamster", "refseq_name": "ATP-dependent RNA helicase DHX8 isoform X4", "refseq_ac": [ { "id": "XP_027283725", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283725", "type": "external" } ], "gene_names_uniprotkb": "LOC103158905", "gene_names_refseq": "LOC103158905", "protein_names_uniprotkb": "ATP-dependent RNA helicase DHX8; 3.6.4.13; DEAH box protein 8", "protein_names_refseq": "ATP-dependent RNA helicase DHX8 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:103158905)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in pre-mRNA splicing as component of the spliceosome. Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003724 RNA helicase activity", "go_cellular_component": "GO:0071013 catalytic step 2 spliceosome", "go_biological_process": "GO:0000390 spliceosomal complex disassembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GID0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GIE8-1", "uniprot_id": [ { "id": "A0A9J7GIE8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GIE8", "type": "external" } ], "mass": 85135.0, "length": 778, "protein_name": "Serine/threonine-protein kinase BRSK1 isoform X2", "gene_name": "Brsk1", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase BRSK1 isoform X2", "refseq_ac": [ { "id": "XP_027286493", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286493", "type": "external" } ], "gene_names_uniprotkb": "Brsk1", "gene_names_refseq": "Brsk1", "protein_names_uniprotkb": "Serine/threonine-protein kinase BRSK1 isoform X2", "protein_names_refseq": "serine/threonine-protein kinase BRSK1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772369)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0050321 tau-protein kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005813 centrosome", "go_biological_process": "GO:0007399 nervous system development;GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GIE8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GIK1-1", "uniprot_id": [ { "id": "A0A9J7GIK1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GIK1", "type": "external" } ], "mass": 193887.0, "length": 1718, "protein_name": "DNA-directed RNA polymerase subunit", "gene_name": "Polr1a", "organism": "Hamster", "refseq_name": "DNA-directed RNA polymerase I subunit RPA1 isoform X3", "refseq_ac": [ { "id": "XP_027285306", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285306", "type": "external" } ], "gene_names_uniprotkb": "Polr1a", "gene_names_refseq": "Polr1a", "protein_names_uniprotkb": "DNA-directed RNA polymerase subunit; 2.7.7.6", "protein_names_refseq": "DNA-directed RNA polymerase I subunit RPA1 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100767957)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "3.1.13.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.-", "type": "external" }, { "id": "2.7.7.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.48", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0046872 metal ion binding;GO:0003899 DNA-directed RNA polymerase activity", "go_cellular_component": "GO:0005694 chromosome;GO:0005736 RNA polymerase I complex", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GIK1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GIK2-1", "uniprot_id": [ { "id": "A0A9J7GIK2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GIK2", "type": "external" } ], "mass": 46873.0, "length": 447, "protein_name": "B-cell lymphoma 3 protein isoform X2", "gene_name": "Bcl3", "organism": "Hamster", "refseq_name": "B-cell lymphoma 3 protein isoform X2", "refseq_ac": [ { "id": "XP_027286670", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286670", "type": "external" } ], "gene_names_uniprotkb": "Bcl3", "gene_names_refseq": "Bcl3", "protein_names_uniprotkb": "B-cell lymphoma 3 protein isoform X2", "protein_names_refseq": "B-cell lymphoma 3 protein isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100751077)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051059 NF-kappaB binding;GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0051707 response to other organism;GO:0006351 DNA-templated transcription;GO:0010628 positive regulation of gene expression;GO:0043066 negative regulation of apoptotic process;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GIK2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GIM6-1", "uniprot_id": [ { "id": "A0A9J7GIM6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GIM6", "type": "external" } ], "mass": 28283.0, "length": 247, "protein_name": "E3 SUMO-protein ligase NSE2", "gene_name": "LOC103159000", "organism": "Hamster", "refseq_name": "E3 SUMO-protein ligase NSE2 isoform X1", "refseq_ac": [ { "id": "XP_027287405", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287405", "type": "external" } ], "gene_names_uniprotkb": "LOC103159000", "gene_names_refseq": "LOC103159000", "protein_names_uniprotkb": "E3 SUMO-protein ligase NSE2; E3 SUMO-protein transferase NSE2; MMS21 homolog; Non-structural maintenance of chromosomes element 2 homolog", "protein_names_refseq": "E3 SUMO-protein ligase NSE2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:103159000)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048603.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand break repair by homologous recombination. Is not be required for the stability of the complex. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. Acts as an E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TSNAX, the shelterin complex subunits TERF1, TERF2, TINF2 and TERF2IP, RAD51AP1, and maybe the cohesin components RAD21 and STAG2. Required for recruitment of telomeres to PML nuclear bodies. Required for sister chromatid cohesion during prometaphase and mitotic progression., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0061665 SUMO ligase activity;GO:0008270 zinc ion binding;GO:0004842 ubiquitin-protein transferase activity;GO:0016874 ligase activity", "go_cellular_component": "GO:0016605 PML body;GO:0000781 chromosome, telomeric region;GO:0030915 Smc5-Smc6 complex;GO:0005634 nucleus", "go_biological_process": "GO:0016925 protein sumoylation;GO:0051301 cell division;GO:0016567 protein ubiquitination;GO:0000724 double-strand break repair via homologous recombination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GIM6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GIN7-1", "uniprot_id": [ { "id": "A0A9J7GIN7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GIN7", "type": "external" } ], "mass": 126058.0, "length": 1121, "protein_name": "Eukaryotic translation initiation factor 2-alpha kinase 3", "gene_name": "Eif2ak3", "organism": "Hamster", "refseq_name": "eukaryotic translation initiation factor 2-alpha kinase 3 isoform X2", "refseq_ac": [ { "id": "XP_027285344", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285344", "type": "external" } ], "gene_names_uniprotkb": "Eif2ak3", "gene_names_refseq": "Eif2ak3", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 2-alpha kinase 3; 2.7.10.2; 2.7.11.1; PRKR-like endoplasmic reticulum kinase; Pancreatic eIF2-alpha kinase; Protein tyrosine kinase EIF2AK3", "protein_names_refseq": "eukaryotic translation initiation factor 2-alpha kinase 3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100765343)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027285344.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity;GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0003743 translation initiation factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0032055 negative regulation of translation in response to stress;GO:0034976 response to endoplasmic reticulum stress;GO:0006986 response to unfolded protein", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GIN7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GIR8-1", "uniprot_id": [ { "id": "A0A9J7GIR8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GIR8", "type": "external" } ], "mass": 78430.0, "length": 697, "protein_name": "Protein kinase C", "gene_name": "Prkcg", "organism": "Hamster", "refseq_name": "protein kinase C gamma type isoform X2", "refseq_ac": [ { "id": "XP_027286817", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286817", "type": "external" } ], "gene_names_uniprotkb": "Prkcg", "gene_names_refseq": "Prkcg", "protein_names_uniprotkb": "Protein kinase C; 2.7.11.13", "protein_names_refseq": "protein kinase C gamma type isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762950)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0048471 perinuclear region of cytoplasm;GO:0099524 postsynaptic cytosol", "go_biological_process": "GO:0048511 rhythmic process;GO:0023051 regulation of signaling;GO:0010646 regulation of cell communication", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GIR8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GIS3-1", "uniprot_id": [ { "id": "A0A9J7GIS3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GIS3", "type": "external" } ], "mass": 26677.0, "length": 249, "protein_name": "Triosephosphate isomerase", "gene_name": "Tpi1", "organism": "Hamster", "refseq_name": "triosephosphate isomerase isoform X2", "refseq_ac": [ { "id": "XP_027284060", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284060", "type": "external" } ], "gene_names_uniprotkb": "Tpi1", "gene_names_refseq": "Tpi1", "protein_names_uniprotkb": "Triosephosphate isomerase; 5.3.1.1", "protein_names_refseq": "triosephosphate isomerase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767338)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids., [UniProtKB, UniProtKB]; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.3.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.1.1", "type": "external" } ], "go_molecular_function": "GO:0004807 triose-phosphate isomerase activity;GO:0008929 methylglyoxal synthase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0019563 glycerol catabolic process;GO:0006094 gluconeogenesis;GO:0006096 glycolytic process;GO:0046166 glyceraldehyde-3-phosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GIS3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GL56-1", "uniprot_id": [ { "id": "A0A9J7GL56_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GL56", "type": "external" } ], "mass": 92593.0, "length": 812, "protein_name": "Oligophrenin-1", "gene_name": "LOC100765371", "organism": "Hamster", "refseq_name": "oligophrenin-1 isoform X4", "refseq_ac": [ { "id": "XP_027287512", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287512", "type": "external" } ], "gene_names_uniprotkb": "LOC100765371", "gene_names_refseq": "LOC100765371", "protein_names_uniprotkb": "Oligophrenin-1", "protein_names_refseq": "oligophrenin-1 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100765371)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0015629 actin cytoskeleton;GO:0043195 terminal bouton;GO:0043197 dendritic spine", "go_biological_process": "GO:0007165 signal transduction;GO:0007399 nervous system development;GO:0030100 regulation of endocytosis;GO:0030036 actin cytoskeleton organization;GO:0051966 regulation of synaptic transmission, glutamatergic", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GL56-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GIV4-1", "uniprot_id": [ { "id": "A0A9J7GIV4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GIV4", "type": "external" } ], "mass": 266587.0, "length": 2328, "protein_name": "Coagulation factor VIII", "gene_name": "F8", "organism": "Hamster", "refseq_name": "coagulation factor VIII isoform X2", "refseq_ac": [ { "id": "XP_027288292", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288292", "type": "external" } ], "gene_names_uniprotkb": "F8", "gene_names_refseq": "F8", "protein_names_uniprotkb": "Coagulation factor VIII; Procoagulant component", "protein_names_refseq": "coagulation factor VIII isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:107977029)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016491 oxidoreductase activity;GO:0005507 copper ion binding;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0031091 platelet alpha granule", "go_biological_process": "GO:0006953 acute-phase response;GO:0007596 blood coagulation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GIV4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GIY7-1", "uniprot_id": [ { "id": "A0A9J7GIY7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GIY7", "type": "external" } ], "mass": 42696.0, "length": 388, "protein_name": "Cell adhesion molecule 4", "gene_name": "LOC113837349", "organism": "Hamster", "refseq_name": "cell adhesion molecule 4", "refseq_ac": [ { "id": "XP_027286954", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286954", "type": "external" } ], "gene_names_uniprotkb": "LOC113837349", "gene_names_refseq": "LOC113837349", "protein_names_uniprotkb": "Cell adhesion molecule 4; Immunoglobulin superfamily member 4C; Nectin-like protein 4", "protein_names_refseq": "cell adhesion molecule 4", "tax_id": 10029, "disease": "", "pathway": " (cge:113837349)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor-suppressor activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043184 vascular endothelial growth factor receptor 2 binding", "go_cellular_component": "GO:0016020 membrane;GO:0044291 cell-cell contact zone", "go_biological_process": "GO:0061041 regulation of wound healing;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0035020 regulation of Rac protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GIY7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GJ30-1", "uniprot_id": [ { "id": "A0A9J7GJ30_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GJ30", "type": "external" } ], "mass": 40350.0, "length": 353, "protein_name": "Vascular endothelial growth factor D", "gene_name": "Vegfd", "organism": "Hamster", "refseq_name": "vascular endothelial growth factor D isoform X6", "refseq_ac": [ { "id": "XP_007642034", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642034", "type": "external" } ], "gene_names_uniprotkb": "Vegfd", "gene_names_refseq": "Vegfd", "protein_names_uniprotkb": "Vascular endothelial growth factor D; c-Fos-induced growth factor", "protein_names_refseq": "vascular endothelial growth factor D isoform X6", "tax_id": 10029, "disease": "", "pathway": " (cge:100773421)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613952.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-3 (Flt4) receptor., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042056 chemoattractant activity;GO:0008083 growth factor activity;GO:0005172 vascular endothelial growth factor receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane", "go_biological_process": "GO:0030154 cell differentiation;GO:0001666 response to hypoxia;GO:0045766 positive regulation of angiogenesis;GO:0001938 positive regulation of endothelial cell proliferation;GO:0051781 positive regulation of cell division", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GJ30-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GJ49-1", "uniprot_id": [ { "id": "A0A9J7GJ49_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GJ49", "type": "external" } ], "mass": 53890.0, "length": 496, "protein_name": "Methyl-CpG-binding protein 2", "gene_name": "Mecp2", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: methyl-CpG-binding protein 2 isoform X2", "refseq_ac": [ { "id": "XP_027288254", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288254", "type": "external" } ], "gene_names_uniprotkb": "Mecp2", "gene_names_refseq": "Mecp2", "protein_names_uniprotkb": "Methyl-CpG-binding protein 2; MeCp-2 protein; MeCp2", "protein_names_refseq": "LOW QUALITY PROTEIN: methyl-CpG-binding protein 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100773625)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008327 methyl-CpG binding;GO:1990841 promoter-specific chromatin binding;GO:0010385 double-stranded methylated DNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0000792 heterochromatin", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0010629 negative regulation of gene expression;GO:0035176 social behavior;GO:0043576 regulation of respiratory gaseous exchange", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GJ49-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GJ56-1", "uniprot_id": [ { "id": "A0A9J7GJ56_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GJ56", "type": "external" } ], "mass": 52696.0, "length": 487, "protein_name": "Otoconin-90", "gene_name": "Oc90", "organism": "Hamster", "refseq_name": "otoconin-90 isoform X3", "refseq_ac": [ { "id": "XP_027287364", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287364", "type": "external" } ], "gene_names_uniprotkb": "Oc90", "gene_names_refseq": "Oc90", "protein_names_uniprotkb": "Otoconin-90", "protein_names_refseq": "otoconin-90 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100754087)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048603.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Major protein of the otoconia, a calcium carbonate structure in the saccule and utricle of the ear. Together with OTOL1, acts as a scaffold for otoconia biomineralization: sequesters calcium and forms interconnecting fibrils between otoconia that are incorporated into the calcium crystal structure. Together with OTOL1, modulates calcite crystal morphology and growth kinetics. It is unlikely that this protein has phospholipase A2 activity., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005543 phospholipid binding;GO:0005509 calcium ion binding;GO:0004623 phospholipase A2 activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0031012 extracellular matrix", "go_biological_process": "GO:0016042 lipid catabolic process;GO:0050482 arachidonate secretion;GO:0006644 phospholipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GJ56-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GJ81-1", "uniprot_id": [ { "id": "A0A9J7GJ81_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GJ81", "type": "external" } ], "mass": 38884.0, "length": 354, "protein_name": "CCN family member 3", "gene_name": "Ccn3", "organism": "Hamster", "refseq_name": "CCN family member 3 isoform X2", "refseq_ac": [ { "id": "XP_027287209", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287209", "type": "external" } ], "gene_names_uniprotkb": "Ccn3", "gene_names_refseq": "Ccn3", "protein_names_uniprotkb": "CCN family member 3; Cellular communication network factor 3; Nephroblastoma-overexpressed gene protein homolog; Protein NOV homolog", "protein_names_refseq": "CCN family member 3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100755660)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048603.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0008201 heparin binding;GO:0008083 growth factor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0031012 extracellular matrix;GO:0005921 gap junction", "go_biological_process": "GO:0007155 cell adhesion;GO:0045597 positive regulation of cell differentiation;GO:0002062 chondrocyte differentiation;GO:0051239 regulation of multicellular organismal process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GJ81-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GJE7-1", "uniprot_id": [ { "id": "A0A9J7GJE7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GJE7", "type": "external" } ], "mass": 86449.0, "length": 771, "protein_name": "Diamine acetyltransferase 1", "gene_name": "Satl1", "organism": "Hamster", "refseq_name": "spermidine/spermine N(1)-acetyltransferase-like protein 1 isoform X2", "refseq_ac": [ { "id": "XP_027288739", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288739", "type": "external" } ], "gene_names_uniprotkb": "Satl1", "gene_names_refseq": "Satl1", "protein_names_uniprotkb": "Diamine acetyltransferase 1; Polyamine N-acetyltransferase 1; Putrescine acetyltransferase; Spermidine/spermine N(1)-acetyltransferase 1", "protein_names_refseq": "spermidine/spermine N(1)-acetyltransferase-like protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756097)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 16% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine = spermidine >> spermine > N(1)-acetylspermine. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. Also involved in the regulation of polyamine transport out of cells. Also acts on 1,3-diaminopropane and 1,5-diaminopentane., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.57", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.57", "type": "external" } ], "go_molecular_function": "GO:0004145 diamine N-acetyltransferase activity;GO:0019809 spermidine binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0032918 spermidine acetylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GJE7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GJQ7-1", "uniprot_id": [ { "id": "A0A9J7GJQ7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GJQ7", "type": "external" } ], "mass": 99102.0, "length": 909, "protein_name": "Androgen receptor", "gene_name": "Ar", "organism": "Hamster", "refseq_name": "androgen receptor isoform X3", "refseq_ac": [ { "id": "XP_027287560", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287560", "type": "external" } ], "gene_names_uniprotkb": "Ar", "gene_names_refseq": "Ar", "protein_names_uniprotkb": "Androgen receptor; Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4", "protein_names_refseq": "androgen receptor isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100752675)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0019904 protein domain specific binding;GO:0005496 steroid binding;GO:0043565 sequence-specific DNA binding;GO:0004879 nuclear receptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0046661 male sex differentiation;GO:0006351 DNA-templated transcription;GO:0007283 spermatogenesis;GO:0030521 androgen receptor signaling pathway;GO:0060736 prostate gland growth", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GJQ7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GJW5-1", "uniprot_id": [ { "id": "A0A9J7GJW5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GJW5", "type": "external" } ], "mass": 129161.0, "length": 1161, "protein_name": "Proto-oncogene tyrosine-protein kinase receptor Ret", "gene_name": "Ret", "organism": "Hamster", "refseq_name": "proto-oncogene tyrosine-protein kinase receptor Ret isoform X2", "refseq_ac": [ { "id": "XP_027285051", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285051", "type": "external" } ], "gene_names_uniprotkb": "Ret", "gene_names_refseq": "Ret", "protein_names_uniprotkb": "Proto-oncogene tyrosine-protein kinase receptor Ret; 2.7.10.1", "protein_names_refseq": "proto-oncogene tyrosine-protein kinase receptor Ret isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772741)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 6% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027285051.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0005509 calcium ion binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex;GO:0010008 endosome membrane", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0007399 nervous system development;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GJW5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GK83-1", "uniprot_id": [ { "id": "A0A9J7GK83_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GK83", "type": "external" } ], "mass": 33899.0, "length": 329, "protein_name": "Protransforming growth factor alpha", "gene_name": "Tgfa", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: protransforming growth factor alpha isoform X2", "refseq_ac": [ { "id": "XP_027284429", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284429", "type": "external" } ], "gene_names_uniprotkb": "Tgfa", "gene_names_refseq": "Tgfa", "protein_names_uniprotkb": "Protransforming growth factor alpha", "protein_names_refseq": "LOW QUALITY PROTEIN: protransforming growth factor alpha isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754730)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 32% of CDS bases internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005154 epidermal growth factor receptor binding;GO:0008083 growth factor activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0072574 hepatocyte proliferation;GO:0008284 positive regulation of cell population proliferation;GO:0007173 epidermal growth factor receptor signaling pathway;GO:0051781 positive regulation of cell division;GO:0045840 positive regulation of mitotic nuclear division", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GK83-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GKL2-1", "uniprot_id": [ { "id": "A0A9J7GKL2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GKL2", "type": "external" } ], "mass": 84847.0, "length": 723, "protein_name": "Zinc finger protein 54-like isoform X1", "gene_name": "LOC100757167", "organism": "Hamster", "refseq_name": "zinc finger protein 54-like isoform X1", "refseq_ac": [ { "id": "XP_007651383", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651383", "type": "external" } ], "gene_names_uniprotkb": "LOC100757167", "gene_names_refseq": "LOC100757167", "protein_names_uniprotkb": "Zinc finger protein 54-like isoform X1", "protein_names_refseq": "zinc finger protein 54-like isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100757167)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615585.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0022603 regulation of anatomical structure morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GKL2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GKQ3-1", "uniprot_id": [ { "id": "A0A9J7GKQ3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GKQ3", "type": "external" } ], "mass": 76251.0, "length": 691, "protein_name": "long-chain-fatty-acid--CoA ligase", "gene_name": "Slc27a5", "organism": "Hamster", "refseq_name": "bile acyl-CoA synthetase isoform X2", "refseq_ac": [ { "id": "XP_027287020", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287020", "type": "external" } ], "gene_names_uniprotkb": "Slc27a5", "gene_names_refseq": "Slc27a5", "protein_names_uniprotkb": "long-chain-fatty-acid--CoA ligase; 6.2.1.3; Long-chain-fatty-acid--CoA ligase", "protein_names_refseq": "bile acyl-CoA synthetase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100765567)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.3", "type": "external" }, { "id": "6.2.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.15", "type": "external" }, { "id": "6.2.1.76", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.76", "type": "external" } ], "go_molecular_function": "GO:0005324 long-chain fatty acid transmembrane transporter activity;GO:0000166 nucleotide binding;GO:0004467 long-chain fatty acid-CoA ligase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0044539 long-chain fatty acid import into cell;GO:0008206 bile acid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GKQ3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GKU3-1", "uniprot_id": [ { "id": "A0A9J7GKU3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GKU3", "type": "external" } ], "mass": 39839.0, "length": 352, "protein_name": "Eukaryotic translation initiation factor 3 subunit H", "gene_name": "Eif3h", "organism": "Hamster", "refseq_name": "eukaryotic translation initiation factor 3 subunit H isoform X2", "refseq_ac": [ { "id": "XP_027287222", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287222", "type": "external" } ], "gene_names_uniprotkb": "Eif3h; EIF3H; EIF3S3", "gene_names_refseq": "Eif3h", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 3 subunit H; Eukaryotic translation initiation factor 3 subunit 3; eIF-3 gamma; eIF3 p40 subunit; eIF3h", "protein_names_refseq": "eukaryotic translation initiation factor 3 subunit H isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100751998)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048603.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008237 metallopeptidase activity;GO:0003743 translation initiation factor activity", "go_cellular_component": "GO:0016282 eukaryotic 43S preinitiation complex;GO:0033290 eukaryotic 48S preinitiation complex;GO:0005852 eukaryotic translation initiation factor 3 complex", "go_biological_process": "GO:0001732 formation of cytoplasmic translation initiation complex", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GKU3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GKU6-1", "uniprot_id": [ { "id": "A0A9J7GKU6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GKU6", "type": "external" } ], "mass": 40990.0, "length": 370, "protein_name": "Nucleoporin SEH1", "gene_name": "LOC113837910", "organism": "Hamster", "refseq_name": "nucleoporin SEH1-like", "refseq_ac": [ { "id": "XP_027289533", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289533", "type": "external" } ], "gene_names_uniprotkb": "LOC113837910", "gene_names_refseq": "LOC113837910", "protein_names_uniprotkb": "Nucleoporin SEH1; GATOR2 complex protein SEH1; Nucleoporin seh1; Nup107-160 subcomplex subunit SEH1", "protein_names_refseq": "nucleoporin SEH1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113837910)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276875.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; As a component of the GATOR2 complex, functions as an activator of the amino acid-sensing branch of the mTORC1 signaling pathway. The GATOR2 complex indirectly activates mTORC1 through the inhibition of the GATOR1 subcomplex. GATOR2 probably acts as an E3 ubiquitin-protein ligase toward GATOR1. In the presence of abundant amino acids, the GATOR2 complex mediates ubiquitination of the NPRL2 core component of the GATOR1 complex, leading to GATOR1 inactivation. In the absence of amino acids, GATOR2 is inhibited, activating the GATOR1 complex. Within the GATOR2 complex, SEC13 and SEH1L are required to stabilize the complex., [UniProtKB, UniProtKB]; Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0031080 nuclear pore outer ring;GO:0005765 lysosomal membrane;GO:0000776 kinetochore;GO:0035859 Seh1-associated complex", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0007059 chromosome segregation;GO:0015031 protein transport;GO:0051301 cell division;GO:0034198 cellular response to amino acid starvation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7GKU6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GKX5-1", "uniprot_id": [ { "id": "A0A9J7GKX5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GKX5", "type": "external" } ], "mass": 307145.0, "length": 2701, "protein_name": "Inositol 1,4,5-trisphosphate receptor", "gene_name": "Itpr2", "organism": "Hamster", "refseq_name": "inositol 1,4,5-trisphosphate receptor type 2 isoform X2", "refseq_ac": [ { "id": "XP_027285913", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285913", "type": "external" } ], "gene_names_uniprotkb": "Itpr2", "gene_names_refseq": "Itpr2", "protein_names_uniprotkb": "Inositol 1,4,5-trisphosphate receptor", "protein_names_refseq": "inositol 1,4,5-trisphosphate receptor type 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100758965)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Inositol 1,4,5-trisphosphate-gated calcium channel that upon inositol 1,4,5-trisphosphate binding transports calcium from the endoplasmic reticulum lumen to cytoplasm. Exists in two states; a long-lived closed state where the channel is essentially 'parked' with only very rare visits to an open state and that ligands facilitate the transition from the 'parked' state into a 'drive' mode represented by periods of bursting activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0070679 inositol 1,4,5 trisphosphate binding;GO:0005220 inositol 1,4,5-trisphosphate-gated calcium channel activity;GO:0005524 ATP binding;GO:0005543 phospholipid binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0030658 transport vesicle membrane;GO:0016529 sarcoplasmic reticulum", "go_biological_process": "GO:0051209 release of sequestered calcium ion into cytosol", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GKX5-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GL37-1", "uniprot_id": [ { "id": "A0A9J7GL37_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GL37", "type": "external" } ], "mass": 55686.0, "length": 501, "protein_name": "Xaa-Pro dipeptidase", "gene_name": "Pepd", "organism": "Hamster", "refseq_name": "xaa-Pro dipeptidase isoform X2", "refseq_ac": [ { "id": "XP_027286075", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286075", "type": "external" } ], "gene_names_uniprotkb": "Pepd", "gene_names_refseq": "Pepd", "protein_names_uniprotkb": "Xaa-Pro dipeptidase; 3.4.13.9; Imidodipeptidase; Peptidase D; Proline dipeptidase", "protein_names_refseq": "xaa-Pro dipeptidase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100770474)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Dipeptidase that catalyzes the hydrolysis of dipeptides with a prolyl (Xaa-Pro) or hydroxyprolyl residue in the C-terminal position. The preferred dipeptide substrate is Gly-Pro, but other Xaa-Pro dipeptides, such as Ala-Pro, Met-Pro, Phe-Pro, Val-Pro and Leu-Pro, can be cleaved. Plays an important role in collagen metabolism because the high level of iminoacids in collagen., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.4.13.9", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.13.9", "type": "external" } ], "go_molecular_function": "GO:0030145 manganese ion binding;GO:0070006 metalloaminopeptidase activity;GO:0102009 proline dipeptidase activity", "go_cellular_component": "", "go_biological_process": "GO:0006508 proteolysis;GO:0030574 collagen catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GL37-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GL54-1", "uniprot_id": [ { "id": "A0A9J7GL54_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GL54", "type": "external" } ], "mass": 52555.0, "length": 467, "protein_name": "Mothers against decapentaplegic homolog", "gene_name": "LOC113838959", "organism": "Hamster", "refseq_name": "mothers against decapentaplegic homolog 1-like isoform X1", "refseq_ac": [ { "id": "XP_027290254", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027290254", "type": "external" } ], "gene_names_uniprotkb": "LOC113838959", "gene_names_refseq": "LOC113838959", "protein_names_uniprotkb": "Mothers against decapentaplegic homolog; MAD homolog; Mothers against DPP homolog; SMAD family member", "protein_names_refseq": "mothers against decapentaplegic homolog 1-like isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:113838959)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023277411.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0070411 I-SMAD binding", "go_cellular_component": "GO:0071144 heteromeric SMAD protein complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0030509 BMP signaling pathway;GO:0060395 SMAD protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7GL54-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GL94-1", "uniprot_id": [ { "id": "A0A9J7GL94_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GL94", "type": "external" } ], "mass": 92020.0, "length": 837, "protein_name": "Zinc fingers and homeoboxes protein 2", "gene_name": "Zhx2", "organism": "Hamster", "refseq_name": "zinc fingers and homeoboxes protein 2", "refseq_ac": [ { "id": "XP_027287467", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287467", "type": "external" } ], "gene_names_uniprotkb": "Zhx2", "gene_names_refseq": "Zhx2", "protein_names_uniprotkb": "Zinc fingers and homeoboxes protein 2; Alpha-fetoprotein regulator 1; Regulator of AFP; Zinc finger and homeodomain protein 2", "protein_names_refseq": "zinc fingers and homeoboxes protein 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100769747)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048603.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA. May play a role in retinal development where it regulates the composition of bipolar cell populations, by promoting differentiation of bipolar OFF-type cells. In the brain, may promote maintenance and suppress differentiation of neural progenitor cells in the developing cortex., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0007399 nervous system development;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GL94-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GL99-1", "uniprot_id": [ { "id": "A0A9J7GL99_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GL99", "type": "external" } ], "mass": 55893.0, "length": 491, "protein_name": "Cytochrome P450", "gene_name": "LOC100765152", "organism": "Hamster", "refseq_name": "cytochrome P450 2B1-like isoform X3", "refseq_ac": [ { "id": "XP_027286207", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286207", "type": "external" } ], "gene_names_uniprotkb": "LOC100765152", "gene_names_refseq": "LOC100765152", "protein_names_uniprotkb": "Cytochrome P450; 1.14.14.1", "protein_names_refseq": "cytochrome P450 2B1-like isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100765152)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.14.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.-", "type": "external" }, { "id": "1.14.14.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.1", "type": "external" }, { "id": "1.14.13.n7", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.n7", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0008392 arachidonate epoxygenase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006805 xenobiotic metabolic process;GO:0019373 epoxygenase P450 pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GL99-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GLM8-1", "uniprot_id": [ { "id": "A0A9J7GLM8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GLM8", "type": "external" } ], "mass": 23782.0, "length": 221, "protein_name": "E2 ubiquitin-conjugating enzyme", "gene_name": "Ube2s", "organism": "Hamster", "refseq_name": "ubiquitin-conjugating enzyme E2 S isoform X2", "refseq_ac": [ { "id": "XP_027286482", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286482", "type": "external" } ], "gene_names_uniprotkb": "Ube2s", "gene_names_refseq": "Ube2s", "protein_names_uniprotkb": "E2 ubiquitin-conjugating enzyme; 2.3.2.23", "protein_names_refseq": "ubiquitin-conjugating enzyme E2 S isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774405)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes 'Lys-11'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by specifically elongating 'Lys-11'-linked polyubiquitin chains initiated by the E2 enzyme UBE2C/UBCH10 on APC/C substrates, enhancing the degradation of APC/C substrates by the proteasome and promoting mitotic exit. Also acts by elongating ubiquitin chains initiated by the E2 enzyme UBE2D1/UBCH5 in vitro; it is however unclear whether UBE2D1/UBCH5 acts as an E2 enzyme for the APC/C in vivo. Also involved in ubiquitination and subsequent degradation of VHL, resulting in an accumulation of HIF1A. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, except 'Lys-48'-linked polyubiquitination., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0061631 ubiquitin conjugating enzyme activity", "go_cellular_component": "", "go_biological_process": "GO:0051301 cell division;GO:0010458 exit from mitosis;GO:0031145 anaphase-promoting complex-dependent catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GLM8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GLP7-1", "uniprot_id": [ { "id": "A0A9J7GLP7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GLP7", "type": "external" } ], "mass": 49665.0, "length": 460, "protein_name": "Protein tweety homolog", "gene_name": "Ttyh1", "organism": "Hamster", "refseq_name": "protein tweety homolog 1 isoform X2", "refseq_ac": [ { "id": "XP_027286569", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286569", "type": "external" } ], "gene_names_uniprotkb": "Ttyh1", "gene_names_refseq": "Ttyh1", "protein_names_uniprotkb": "Protein tweety homolog", "protein_names_refseq": "protein tweety homolog 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774128)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Calcium-independent, swelling-dependent volume-regulated anion channel (VRAC-swell) which plays a pivotal role in the process of regulatory volume decrease (RVD) in the brain through the efflux of anions like chloride and organic osmolytes like glutamate., [UniProtKB, UniProtKB, UniProtKB]; Probable chloride channel., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" } ], "go_molecular_function": "GO:0072320 volume-sensitive chloride channel activity;GO:0005229 intracellularly calcium-gated chloride channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030868 smooth endoplasmic reticulum membrane;GO:0034707 chloride channel complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GLP7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GLS3-1", "uniprot_id": [ { "id": "A0A9J7GLS3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GLS3", "type": "external" } ], "mass": 118064.0, "length": 1031, "protein_name": "Aminopeptidase Q", "gene_name": "Lvrn", "organism": "Hamster", "refseq_name": "aminopeptidase Q isoform X2", "refseq_ac": [ { "id": "XP_035294621", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294621", "type": "external" } ], "gene_names_uniprotkb": "Lvrn", "gene_names_refseq": "Lvrn", "protein_names_uniprotkb": "Aminopeptidase Q; Laeverin", "protein_names_refseq": "aminopeptidase Q isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100770836)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 3% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042277 peptide binding;GO:0070006 metalloaminopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0043171 peptide catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GLS3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GLT2-1", "uniprot_id": [ { "id": "A0A9J7GLT2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GLT2", "type": "external" } ], "mass": 131429.0, "length": 1257, "protein_name": "Sal-like protein 3 isoform X2", "gene_name": "Sall3", "organism": "Hamster", "refseq_name": "sal-like protein 3 isoform X2", "refseq_ac": [ { "id": "XP_035294638", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294638", "type": "external" } ], "gene_names_uniprotkb": "Sall3", "gene_names_refseq": "Sall3", "protein_names_uniprotkb": "Sal-like protein 3 isoform X2", "protein_names_refseq": "sal-like protein 3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100765427)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 2% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0001708 cell fate specification;GO:0006351 DNA-templated transcription;GO:0009791 post-embryonic development;GO:0007224 smoothened signaling pathway;GO:0035136 forelimb morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GLT2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GLY5-1", "uniprot_id": [ { "id": "A0A9J7GLY5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GLY5", "type": "external" } ], "mass": 17018.0, "length": 155, "protein_name": "Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial", "gene_name": "LOC100754157", "organism": "Hamster", "refseq_name": "glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial-like", "refseq_ac": [ { "id": "XP_035294943", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294943", "type": "external" } ], "gene_names_uniprotkb": "LOC100754157; GATC", "gene_names_refseq": "LOC100754157", "protein_names_uniprotkb": "Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial; 6.3.5.-; Glu-AdT subunit C", "protein_names_refseq": "glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100754157)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.3.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.5.-", "type": "external" }, { "id": "6.3.5.7", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.5.7", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex", "go_biological_process": "GO:0032543 mitochondrial translation;GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation;GO:0006450 regulation of translational fidelity", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GLY5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GM14-1", "uniprot_id": [ { "id": "A0A9J7GM14_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GM14", "type": "external" } ], "mass": 52435.0, "length": 467, "protein_name": "Mothers against decapentaplegic homolog", "gene_name": "LOC113838617", "organism": "Hamster", "refseq_name": "mothers against decapentaplegic homolog 1-like isoform X1", "refseq_ac": [ { "id": "XP_027290018", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027290018", "type": "external" } ], "gene_names_uniprotkb": "LOC113838617", "gene_names_refseq": "LOC113838617", "protein_names_uniprotkb": "Mothers against decapentaplegic homolog; MAD homolog; Mothers against DPP homolog; SMAD family member", "protein_names_refseq": "mothers against decapentaplegic homolog 1-like isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:113838617)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0070411 I-SMAD binding", "go_cellular_component": "GO:0071144 heteromeric SMAD protein complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0030509 BMP signaling pathway;GO:0060395 SMAD protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7GM14-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GM25-1", "uniprot_id": [ { "id": "A0A9J7GM25_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GM25", "type": "external" } ], "mass": 83423.0, "length": 772, "protein_name": "Low-density lipoprotein receptor-related protein 3", "gene_name": "Lrp3", "organism": "Hamster", "refseq_name": "low-density lipoprotein receptor-related protein 3 isoform X2", "refseq_ac": [ { "id": "XP_027286082", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286082", "type": "external" } ], "gene_names_uniprotkb": "Lrp3", "gene_names_refseq": "Lrp3", "protein_names_uniprotkb": "Low-density lipoprotein receptor-related protein 3; 105 kDa low-density lipoprotein receptor-related protein", "protein_names_refseq": "low-density lipoprotein receptor-related protein 3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100769612)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005905 clathrin-coated pit", "go_biological_process": "GO:0006897 endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GM25-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GM34-1", "uniprot_id": [ { "id": "A0A9J7GM34_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GM34", "type": "external" } ], "mass": 45365.0, "length": 417, "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "Gapdhs", "organism": "Hamster", "refseq_name": "glyceraldehyde-3-phosphate dehydrogenase, testis-specific", "refseq_ac": [ { "id": "XP_016832671", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016832671", "type": "external" } ], "gene_names_uniprotkb": "Gapdhs", "gene_names_refseq": "Gapdhs", "protein_names_uniprotkb": "Glyceraldehyde-3-phosphate dehydrogenase; 1.2.1.12", "protein_names_refseq": "glyceraldehyde-3-phosphate dehydrogenase, testis-specific", "tax_id": 10029, "disease": "", "pathway": " (cge:100767862)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614167.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the conversion of D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate in glycolysis and the reverse reaction in gluconeogenesis. May play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon. Required for sperm motility and male fertility., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.2.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.12", "type": "external" }, { "id": "2.6.99.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.99.-", "type": "external" } ], "go_molecular_function": "GO:0051287 NAD binding;GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity;GO:0050661 NADP binding", "go_cellular_component": "GO:0005829 cytosol;GO:0031514 motile cilium", "go_biological_process": "GO:0006006 glucose metabolic process;GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GM34-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GMB0-1", "uniprot_id": [ { "id": "A0A9J7GMB0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GMB0", "type": "external" } ], "mass": 23059.0, "length": 203, "protein_name": "PTB-containing, cubilin and LRP1-interacting protein", "gene_name": "Pid1", "organism": "Hamster", "refseq_name": "PTB-containing, cubilin and LRP1-interacting protein isoform X2", "refseq_ac": [ { "id": "XP_035295151", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295151", "type": "external" } ], "gene_names_uniprotkb": "Pid1", "gene_names_refseq": "Pid1", "protein_names_uniprotkb": "PTB-containing, cubilin and LRP1-interacting protein; Phosphotyrosine interaction domain-containing protein 1", "protein_names_refseq": "PTB-containing, cubilin and LRP1-interacting protein isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772428)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Increases proliferation of preadipocytes without affecting adipocytic differentiation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0046627 negative regulation of insulin receptor signaling pathway;GO:0042127 regulation of cell population proliferation;GO:0051881 regulation of mitochondrial membrane potential;GO:2000377 regulation of reactive oxygen species metabolic process;GO:0046325 negative regulation of D-glucose import", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GMB0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GNT1-1", "uniprot_id": [ { "id": "A0A9J7GNT1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GNT1", "type": "external" } ], "mass": 204302.0, "length": 1812, "protein_name": "plus-end-directed kinesin ATPase", "gene_name": "Kif1a", "organism": "Hamster", "refseq_name": "kinesin-like protein KIF1A isoform X1", "refseq_ac": [ { "id": "XP_035295167", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295167", "type": "external" } ], "gene_names_uniprotkb": "Kif1a", "gene_names_refseq": "Kif1a", "protein_names_uniprotkb": "plus-end-directed kinesin ATPase; 5.6.1.3", "protein_names_refseq": "kinesin-like protein KIF1A isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100770614)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0008574 plus-end-directed microtubule motor activity", "go_cellular_component": "GO:0005874 microtubule;GO:0045202 synapse;GO:0030658 transport vesicle membrane;GO:1904115 axon cytoplasm", "go_biological_process": "GO:0008089 anterograde axonal transport;GO:0047496 vesicle transport along microtubule", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GNT1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GMC0-1", "uniprot_id": [ { "id": "A0A9J7GMC0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GMC0", "type": "external" } ], "mass": 39398.0, "length": 355, "protein_name": "Nucleoporin SEH1", "gene_name": "LOC113838462", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: nucleoporin SEH1-like", "refseq_ac": [ { "id": "XP_027289938", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289938", "type": "external" } ], "gene_names_uniprotkb": "LOC113838462", "gene_names_refseq": "LOC113838462", "protein_names_uniprotkb": "Nucleoporin SEH1; GATOR2 complex protein SEH1; Nucleoporin seh1; Nup107-160 subcomplex subunit SEH1", "protein_names_refseq": "LOW QUALITY PROTEIN: nucleoporin SEH1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113838462)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276842.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; As a component of the GATOR2 complex, functions as an activator of the amino acid-sensing branch of the mTORC1 signaling pathway. The GATOR2 complex indirectly activates mTORC1 through the inhibition of the GATOR1 subcomplex. GATOR2 probably acts as an E3 ubiquitin-protein ligase toward GATOR1. In the presence of abundant amino acids, the GATOR2 complex mediates ubiquitination of the NPRL2 core component of the GATOR1 complex, leading to GATOR1 inactivation. In the absence of amino acids, GATOR2 is inhibited, activating the GATOR1 complex. Within the GATOR2 complex, SEC13 and SEH1L are required to stabilize the complex., [UniProtKB, UniProtKB]; Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0031080 nuclear pore outer ring;GO:0005765 lysosomal membrane;GO:0000776 kinetochore;GO:0035859 Seh1-associated complex", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0007059 chromosome segregation;GO:0015031 protein transport;GO:0051301 cell division;GO:0034198 cellular response to amino acid starvation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7GMC0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GMC6-1", "uniprot_id": [ { "id": "A0A9J7GMC6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GMC6", "type": "external" } ], "mass": 45775.0, "length": 414, "protein_name": "Ribose-phosphate pyrophosphokinase 1", "gene_name": "LOC100762070", "organism": "Hamster", "refseq_name": "ribose-phosphate pyrophosphokinase 1 isoform X2", "refseq_ac": [ { "id": "XP_027288477", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288477", "type": "external" } ], "gene_names_uniprotkb": "LOC100762070", "gene_names_refseq": "LOC100762070", "protein_names_uniprotkb": "Ribose-phosphate pyrophosphokinase 1; 2.7.6.1; Phosphoribosyl pyrophosphate synthase I", "protein_names_refseq": "ribose-phosphate pyrophosphokinase 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762070)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 23% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016301 kinase activity;GO:0004749 ribose phosphate diphosphokinase activity", "go_cellular_component": "GO:0002189 ribose phosphate diphosphokinase complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0009156 ribonucleoside monophosphate biosynthetic process;GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process;GO:0006164 purine nucleotide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GMC6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GMF3-1", "uniprot_id": [ { "id": "A0A9J7GMF3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GMF3", "type": "external" } ], "mass": 22208.0, "length": 198, "protein_name": "Dual specificity mitogen-activated protein kinase kinase 1", "gene_name": "LOC103158537", "organism": "Hamster", "refseq_name": "dual specificity mitogen-activated protein kinase kinase 1-like isoform X2", "refseq_ac": [ { "id": "XP_027290052", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027290052", "type": "external" } ], "gene_names_uniprotkb": "LOC103158537", "gene_names_refseq": "LOC103158537", "protein_names_uniprotkb": "Dual specificity mitogen-activated protein kinase kinase 1; 2.7.12.2; ERK activator kinase 1; MAPK/ERK kinase 1", "protein_names_refseq": "dual specificity mitogen-activated protein kinase kinase 1-like isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:103158537)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 3% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276862.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0004708 MAP kinase kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005813 centrosome;GO:0031982 vesicle;GO:0070161 anchoring junction", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7GMF3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GMG5-1", "uniprot_id": [ { "id": "A0A9J7GMG5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GMG5", "type": "external" } ], "mass": 39870.0, "length": 360, "protein_name": "Nucleoporin SEH1", "gene_name": "LOC113837903", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: nucleoporin SEH1-like", "refseq_ac": [ { "id": "XP_027289526", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289526", "type": "external" } ], "gene_names_uniprotkb": "LOC113837903", "gene_names_refseq": "LOC113837903", "protein_names_uniprotkb": "Nucleoporin SEH1; GATOR2 complex protein SEH1; Nucleoporin seh1; Nup107-160 subcomplex subunit SEH1", "protein_names_refseq": "LOW QUALITY PROTEIN: nucleoporin SEH1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113837903)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; As a component of the GATOR2 complex, functions as an activator of the amino acid-sensing branch of the mTORC1 signaling pathway. The GATOR2 complex indirectly activates mTORC1 through the inhibition of the GATOR1 subcomplex. GATOR2 probably acts as an E3 ubiquitin-protein ligase toward GATOR1. In the presence of abundant amino acids, the GATOR2 complex mediates ubiquitination of the NPRL2 core component of the GATOR1 complex, leading to GATOR1 inactivation. In the absence of amino acids, GATOR2 is inhibited, activating the GATOR1 complex. Within the GATOR2 complex, SEC13 and SEH1L are required to stabilize the complex., [UniProtKB, UniProtKB]; Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0031080 nuclear pore outer ring;GO:0005765 lysosomal membrane;GO:0000776 kinetochore;GO:0035859 Seh1-associated complex", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0007059 chromosome segregation;GO:0015031 protein transport;GO:0051301 cell division;GO:0034198 cellular response to amino acid starvation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7GMG5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GMH5-1", "uniprot_id": [ { "id": "A0A9J7GMH5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GMH5", "type": "external" } ], "mass": 37713.0, "length": 337, "protein_name": "SMAD family member 1", "gene_name": "LOC113837941", "organism": "Hamster", "refseq_name": "mothers against decapentaplegic homolog 1-like", "refseq_ac": [ { "id": "XP_027289556", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289556", "type": "external" } ], "gene_names_uniprotkb": "LOC113837941", "gene_names_refseq": "LOC113837941", "protein_names_uniprotkb": "SMAD family member 1; Mothers against decapentaplegic homolog 1", "protein_names_refseq": "mothers against decapentaplegic homolog 1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113837941)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027289556.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0070411 I-SMAD binding", "go_cellular_component": "GO:0071144 heteromeric SMAD protein complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0030509 BMP signaling pathway;GO:0060395 SMAD protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7GMH5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GMH9-1", "uniprot_id": [ { "id": "A0A9J7GMH9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GMH9", "type": "external" } ], "mass": 32432.0, "length": 283, "protein_name": "THO complex subunit 1", "gene_name": "LOC100758451", "organism": "Hamster", "refseq_name": "THO complex subunit 1 isoform X2", "refseq_ac": [ { "id": "XP_035295051", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295051", "type": "external" } ], "gene_names_uniprotkb": "LOC100758451", "gene_names_refseq": "LOC100758451", "protein_names_uniprotkb": "THO complex subunit 1; Nuclear matrix protein p84", "protein_names_refseq": "THO complex subunit 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100758451)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. Required for efficient export of polyadenylated RNA. The THOC1-THOC2-THOC3 core complex alone is sufficient to bind export factor NXF1-NXT1 and promote ATPase activity of DDX39B. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NXF1 pathway. Regulates transcriptional elongation of a subset of genes. Involved in genome stability by preventing co-transcriptional R-loop formation. May play a role in hair cell formation, hence may be involved in hearing., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0016363 nuclear matrix;GO:0000445 THO complex part of transcription export complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006397 mRNA processing;GO:0006406 mRNA export from nucleus;GO:0007165 signal transduction;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GMH9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GMI2-1", "uniprot_id": [ { "id": "A0A9J7GMI2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GMI2", "type": "external" } ], "mass": 68880.0, "length": 611, "protein_name": "Polynucleotide 5'-hydroxyl-kinase NOL9", "gene_name": "Nol9", "organism": "Hamster", "refseq_name": "polynucleotide 5'-hydroxyl-kinase NOL9 isoform X3", "refseq_ac": [ { "id": "XP_035295267", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295267", "type": "external" } ], "gene_names_uniprotkb": "Nol9", "gene_names_refseq": "Nol9", "protein_names_uniprotkb": "Polynucleotide 5'-hydroxyl-kinase NOL9; 2.7.1.78; Nucleolar protein 9", "protein_names_refseq": "polynucleotide 5'-hydroxyl-kinase NOL9 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100768603)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 147 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) and transcript sequence (IACG01178018.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: incomplete on the amino end., [RefSeq]; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of single-stranded and double-stranded RNA and DNA substrates. Involved in rRNA processing and its kinase activity is required for the processing of the 32S precursor into 5.8S and 28S rRNAs, more specifically for the generation of the major 5.8S(S) form. Required for the efficient pre-rRNA processing of internal transcribed spacer 2 (ITS2). Associates with LAS1L to form an ITS2 pre-rRNA endonuclease-kinase complex and is responsible for the transport of this complex into the nucleolus., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.78", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.78", "type": "external" }, { "id": "3.1.3.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.32", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0051734 ATP-dependent polynucleotide 5'-hydroxyl-kinase activity", "go_cellular_component": "GO:0005730 nucleolus", "go_biological_process": "GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GMI2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GMI5-1", "uniprot_id": [ { "id": "A0A9J7GMI5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GMI5", "type": "external" } ], "mass": 56883.0, "length": 524, "protein_name": "Ciliary neurotrophic factor receptor subunit alpha", "gene_name": "Cntfr", "organism": "Hamster", "refseq_name": "ciliary neurotrophic factor receptor subunit alpha isoform X2", "refseq_ac": [ { "id": "XP_035294587", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294587", "type": "external" } ], "gene_names_uniprotkb": "Cntfr", "gene_names_refseq": "Cntfr", "protein_names_uniprotkb": "Ciliary neurotrophic factor receptor subunit alpha", "protein_names_refseq": "ciliary neurotrophic factor receptor subunit alpha isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100753725)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 29% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Binds to CNTF. The alpha subunit provides the receptor specificity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004897 ciliary neurotrophic factor receptor activity;GO:0004921 interleukin-11 receptor activity;GO:0019970 interleukin-11 binding", "go_cellular_component": "GO:0070110 ciliary neurotrophic factor receptor complex;GO:0009897 external side of plasma membrane;GO:0097059 CNTFR-CLCF1 complex", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GMI5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GMJ2-1", "uniprot_id": [ { "id": "A0A9J7GMJ2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GMJ2", "type": "external" } ], "mass": 40352.0, "length": 360, "protein_name": "Nucleoporin SEH1", "gene_name": "LOC100770516", "organism": "Hamster", "refseq_name": "nucleoporin SEH1 isoform X2", "refseq_ac": [ { "id": "XP_027290171", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027290171", "type": "external" } ], "gene_names_uniprotkb": "LOC100770516", "gene_names_refseq": "LOC100770516", "protein_names_uniprotkb": "Nucleoporin SEH1; GATOR2 complex protein SEH1; Nucleoporin seh1; Nup107-160 subcomplex subunit SEH1", "protein_names_refseq": "nucleoporin SEH1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100770516)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023277119.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; As a component of the GATOR2 complex, functions as an activator of the amino acid-sensing branch of the mTORC1 signaling pathway. The GATOR2 complex indirectly activates mTORC1 through the inhibition of the GATOR1 subcomplex. GATOR2 probably acts as an E3 ubiquitin-protein ligase toward GATOR1. In the presence of abundant amino acids, the GATOR2 complex mediates ubiquitination of the NPRL2 core component of the GATOR1 complex, leading to GATOR1 inactivation. In the absence of amino acids, GATOR2 is inhibited, activating the GATOR1 complex. Within the GATOR2 complex, SEC13 and SEH1L are required to stabilize the complex., [UniProtKB, UniProtKB]; Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0031080 nuclear pore outer ring;GO:0005765 lysosomal membrane;GO:0000776 kinetochore;GO:0035859 Seh1-associated complex", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0007059 chromosome segregation;GO:0015031 protein transport;GO:0051301 cell division;GO:0034198 cellular response to amino acid starvation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7GMJ2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GMJ6-1", "uniprot_id": [ { "id": "A0A9J7GMJ6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GMJ6", "type": "external" } ], "mass": 30353.0, "length": 272, "protein_name": "Lipid transferase CIDEA", "gene_name": "Cidea", "organism": "Hamster", "refseq_name": "cell death activator CIDE-A isoform X2", "refseq_ac": [ { "id": "XP_035294607", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294607", "type": "external" } ], "gene_names_uniprotkb": "Cidea", "gene_names_refseq": "Cidea", "protein_names_uniprotkb": "Lipid transferase CIDEA; Cell death activator CIDE-A; Cell death-inducing DFFA-like effector A", "protein_names_refseq": "cell death activator CIDE-A isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763404)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 23% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005811 lipid droplet;GO:0005829 cytosol", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006915 apoptotic process;GO:0050995 negative regulation of lipid catabolic process;GO:0042981 regulation of apoptotic process;GO:0019915 lipid storage", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GMJ6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GMK6-1", "uniprot_id": [ { "id": "A0A9J7GMK6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GMK6", "type": "external" } ], "mass": 40218.0, "length": 374, "protein_name": "Monocyte differentiation antigen CD14", "gene_name": "Cd14", "organism": "Hamster", "refseq_name": "monocyte differentiation antigen CD14", "refseq_ac": [ { "id": "XP_035294629", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294629", "type": "external" } ], "gene_names_uniprotkb": "Cd14", "gene_names_refseq": "Cd14", "protein_names_uniprotkb": "Monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein", "protein_names_refseq": "monocyte differentiation antigen CD14", "tax_id": 10029, "disease": "", "pathway": " (cge:100757057)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL(-)) and mediates the cytokine release induced by LDL(-)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001530 lipopolysaccharide binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005794 Golgi apparatus;GO:0045121 membrane raft;GO:0009897 external side of plasma membrane;GO:0046696 lipopolysaccharide receptor complex", "go_biological_process": "GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:0071222 cellular response to lipopolysaccharide;GO:0001819 positive regulation of cytokine production;GO:0034142 toll-like receptor 4 signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GMK6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GMN8-1", "uniprot_id": [ { "id": "A0A9J7GMN8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GMN8", "type": "external" } ], "mass": 127433.0, "length": 1162, "protein_name": "Integrin alpha-2", "gene_name": "Itga2", "organism": "Hamster", "refseq_name": "integrin alpha-2 isoform X2", "refseq_ac": [ { "id": "XP_035294677", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294677", "type": "external" } ], "gene_names_uniprotkb": "Itga2", "gene_names_refseq": "Itga2", "protein_names_uniprotkb": "Integrin alpha-2; CD49 antigen-like family member B; Collagen receptor; Platelet membrane glycoprotein Ia; VLA-2 subunit alpha", "protein_names_refseq": "integrin alpha-2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774579)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0009897 external side of plasma membrane;GO:0008305 integrin complex", "go_biological_process": "GO:0007229 integrin-mediated signaling pathway;GO:0007160 cell-matrix adhesion;GO:0033627 cell adhesion mediated by integrin;GO:0098609 cell-cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GMN8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GMP1-1", "uniprot_id": [ { "id": "A0A9J7GMP1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GMP1", "type": "external" } ], "mass": 44127.0, "length": 400, "protein_name": "Dynein assembly factor with WD repeat domains 1", "gene_name": "LOC100757280", "organism": "Hamster", "refseq_name": "dynein assembly factor with WDR repeat domains 1 isoform X3", "refseq_ac": [ { "id": "XP_035295150", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295150", "type": "external" } ], "gene_names_uniprotkb": "LOC100757280", "gene_names_refseq": "LOC100757280", "protein_names_uniprotkb": "Dynein assembly factor with WD repeat domains 1", "protein_names_refseq": "dynein assembly factor with WDR repeat domains 1 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100757280)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Required for axonemal dynein assembly and ciliary motility in ciliated organs, including Kupffer's vesicle, during embryogenesis. Facilitates the onset of robust cilia motility during development., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030621 U4 snRNA binding;GO:0017070 U6 snRNA binding", "go_cellular_component": "GO:0046540 U4/U6 x U5 tri-snRNP complex", "go_biological_process": "GO:0007507 heart development;GO:0007368 determination of left/right symmetry;GO:0000398 mRNA splicing, via spliceosome;GO:0070286 axonemal dynein complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GMP1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GMP2-1", "uniprot_id": [ { "id": "A0A9J7GMP2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GMP2", "type": "external" } ], "mass": 52650.0, "length": 469, "protein_name": "Mothers against decapentaplegic homolog", "gene_name": "LOC113838231", "organism": "Hamster", "refseq_name": "mothers against decapentaplegic homolog 1-like isoform X3", "refseq_ac": [ { "id": "XP_027289843", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289843", "type": "external" } ], "gene_names_uniprotkb": "LOC113838231", "gene_names_refseq": "LOC113838231", "protein_names_uniprotkb": "Mothers against decapentaplegic homolog; MAD homolog; Mothers against DPP homolog; SMAD family member", "protein_names_refseq": "mothers against decapentaplegic homolog 1-like isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:113838231)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0070411 I-SMAD binding", "go_cellular_component": "GO:0071144 heteromeric SMAD protein complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0030509 BMP signaling pathway;GO:0060395 SMAD protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7GMP2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GMU8-1", "uniprot_id": [ { "id": "A0A9J7GMU8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GMU8", "type": "external" } ], "mass": 52419.0, "length": 464, "protein_name": "Mothers against decapentaplegic homolog", "gene_name": "LOC113838335", "organism": "Hamster", "refseq_name": "mothers against decapentaplegic homolog 1-like isoform X1", "refseq_ac": [ { "id": "XP_027289899", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289899", "type": "external" } ], "gene_names_uniprotkb": "LOC113838335", "gene_names_refseq": "LOC113838335", "protein_names_uniprotkb": "Mothers against decapentaplegic homolog; MAD homolog; Mothers against DPP homolog; SMAD family member", "protein_names_refseq": "mothers against decapentaplegic homolog 1-like isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:113838335)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027289899.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0070411 I-SMAD binding", "go_cellular_component": "GO:0071144 heteromeric SMAD protein complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0030509 BMP signaling pathway;GO:0060395 SMAD protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7GMU8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GMV3-1", "uniprot_id": [ { "id": "A0A9J7GMV3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GMV3", "type": "external" } ], "mass": 75329.0, "length": 687, "protein_name": "Chloride channel protein", "gene_name": "LOC100753750", "organism": "Hamster", "refseq_name": "chloride channel protein ClC-Kb isoform X2", "refseq_ac": [ { "id": "XP_035294773", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294773", "type": "external" } ], "gene_names_uniprotkb": "LOC100753750", "gene_names_refseq": "LOC100753750", "protein_names_uniprotkb": "Chloride channel protein", "protein_names_refseq": "chloride channel protein ClC-Kb isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100753750)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0005247 voltage-gated chloride channel activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane;GO:0034707 chloride channel complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GMV3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GN24-1", "uniprot_id": [ { "id": "A0A9J7GN24_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GN24", "type": "external" } ], "mass": 340021.0, "length": 3103, "protein_name": "Laminin A chain", "gene_name": "Lama1", "organism": "Hamster", "refseq_name": "laminin subunit alpha-1 isoform X2", "refseq_ac": [ { "id": "XP_035294751", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294751", "type": "external" } ], "gene_names_uniprotkb": "Lama1", "gene_names_refseq": "Lama1", "protein_names_uniprotkb": "Laminin A chain", "protein_names_refseq": "laminin subunit alpha-1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100765555)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0005201 extracellular matrix structural constituent", "go_cellular_component": "GO:0005576 extracellular region;GO:0043256 laminin complex", "go_biological_process": "GO:0007155 cell adhesion;GO:0030155 regulation of cell adhesion;GO:0048514 blood vessel morphogenesis;GO:0009887 animal organ morphogenesis;GO:0030334 regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GN24-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GN30-1", "uniprot_id": [ { "id": "A0A9J7GN30_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GN30", "type": "external" } ], "mass": 39780.0, "length": 360, "protein_name": "Nucleoporin SEH1", "gene_name": "LOC113838925", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: nucleoporin SEH1-like", "refseq_ac": [ { "id": "XP_027290236", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027290236", "type": "external" } ], "gene_names_uniprotkb": "LOC113838925", "gene_names_refseq": "LOC113838925", "protein_names_uniprotkb": "Nucleoporin SEH1; GATOR2 complex protein SEH1; Nucleoporin seh1; Nup107-160 subcomplex subunit SEH1", "protein_names_refseq": "LOW QUALITY PROTEIN: nucleoporin SEH1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113838925)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276819.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; As a component of the GATOR2 complex, functions as an activator of the amino acid-sensing branch of the mTORC1 signaling pathway. The GATOR2 complex indirectly activates mTORC1 through the inhibition of the GATOR1 subcomplex. GATOR2 probably acts as an E3 ubiquitin-protein ligase toward GATOR1. In the presence of abundant amino acids, the GATOR2 complex mediates ubiquitination of the NPRL2 core component of the GATOR1 complex, leading to GATOR1 inactivation. In the absence of amino acids, GATOR2 is inhibited, activating the GATOR1 complex. Within the GATOR2 complex, SEC13 and SEH1L are required to stabilize the complex., [UniProtKB, UniProtKB]; Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0031080 nuclear pore outer ring;GO:0005765 lysosomal membrane;GO:0000776 kinetochore;GO:0035859 Seh1-associated complex", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0007059 chromosome segregation;GO:0015031 protein transport;GO:0051301 cell division;GO:0034198 cellular response to amino acid starvation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7GN30-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GN51-1", "uniprot_id": [ { "id": "A0A9J7GN51_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GN51", "type": "external" } ], "mass": 122734.0, "length": 1155, "protein_name": "Transcription intermediary factor 1-beta", "gene_name": "Trim28", "organism": "Hamster", "refseq_name": "transcription intermediary factor 1-beta isoform X2", "refseq_ac": [ { "id": "XP_027286977", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286977", "type": "external" } ], "gene_names_uniprotkb": "Trim28", "gene_names_refseq": "Trim28", "protein_names_uniprotkb": "Transcription intermediary factor 1-beta; 2.3.2.27; E3 SUMO-protein ligase TRIM28; RING-type E3 ubiquitin transferase TIF1-beta; Tripartite motif-containing protein 28", "protein_names_refseq": "transcription intermediary factor 1-beta isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767882)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 26% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0003714 transcription corepressor activity;GO:0061630 ubiquitin protein ligase activity;GO:0019789 SUMO transferase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0000785 chromatin;GO:0032991 protein-containing complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045087 innate immune response;GO:0006346 DNA methylation-dependent constitutive heterochromatin formation;GO:0010604 positive regulation of macromolecule metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GN51-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GQF4-1", "uniprot_id": [ { "id": "A0A9J7GQF4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GQF4", "type": "external" } ], "mass": 54269.0, "length": 482, "protein_name": "Vitamin K-dependent protein C", "gene_name": "Proc", "organism": "Hamster", "refseq_name": "vitamin K-dependent protein C isoform X2", "refseq_ac": [ { "id": "XP_035294947", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294947", "type": "external" } ], "gene_names_uniprotkb": "Proc", "gene_names_refseq": "Proc", "protein_names_uniprotkb": "Vitamin K-dependent protein C; 3.4.21.69; Anticoagulant protein C; Autoprothrombin IIA; Blood coagulation factor XIV", "protein_names_refseq": "vitamin K-dependent protein C isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772264)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0006508 proteolysis;GO:0007596 blood coagulation;GO:0030195 negative regulation of blood coagulation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GQF4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GN76-1", "uniprot_id": [ { "id": "A0A9J7GN76_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GN76", "type": "external" } ], "mass": 37556.0, "length": 334, "protein_name": "Nucleoporin SEH1", "gene_name": "LOC113838934", "organism": "Hamster", "refseq_name": "nucleoporin SEH1-like", "refseq_ac": [ { "id": "XP_027290243", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027290243", "type": "external" } ], "gene_names_uniprotkb": "LOC113838934", "gene_names_refseq": "LOC113838934", "protein_names_uniprotkb": "Nucleoporin SEH1; GATOR2 complex protein SEH1; Nucleoporin seh1; Nup107-160 subcomplex subunit SEH1", "protein_names_refseq": "nucleoporin SEH1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113838934)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; As a component of the GATOR2 complex, functions as an activator of the amino acid-sensing branch of the mTORC1 signaling pathway. The GATOR2 complex indirectly activates mTORC1 through the inhibition of the GATOR1 subcomplex. GATOR2 probably acts as an E3 ubiquitin-protein ligase toward GATOR1. In the presence of abundant amino acids, the GATOR2 complex mediates ubiquitination of the NPRL2 core component of the GATOR1 complex, leading to GATOR1 inactivation. In the absence of amino acids, GATOR2 is inhibited, activating the GATOR1 complex. Within the GATOR2 complex, SEC13 and SEH1L are required to stabilize the complex., [UniProtKB, UniProtKB]; Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0031080 nuclear pore outer ring;GO:0005765 lysosomal membrane;GO:0000776 kinetochore;GO:0035859 Seh1-associated complex", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0007059 chromosome segregation;GO:0015031 protein transport;GO:0051301 cell division;GO:0034198 cellular response to amino acid starvation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7GN76-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GNN2-1", "uniprot_id": [ { "id": "A0A9J7GNN2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GNN2", "type": "external" } ], "mass": 105029.0, "length": 942, "protein_name": "FRAS1-related extracellular matrix protein 1", "gene_name": "Frem1", "organism": "Hamster", "refseq_name": "FRAS1-related extracellular matrix protein 1 isoform X2", "refseq_ac": [ { "id": "XP_035295717", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295717", "type": "external" } ], "gene_names_uniprotkb": "Frem1", "gene_names_refseq": "Frem1", "protein_names_uniprotkb": "FRAS1-related extracellular matrix protein 1; Protein QBRICK", "protein_names_refseq": "FRAS1-related extracellular matrix protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100764944)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Extracellular matrix protein that plays a role in epidermal differentiation and is required for epidermal adhesion during embryonic development., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0030246 carbohydrate binding", "go_cellular_component": "GO:0016020 membrane;GO:0005604 basement membrane", "go_biological_process": "GO:0007155 cell adhesion;GO:0007154 cell communication;GO:0009653 anatomical structure morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GNN2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GND9-1", "uniprot_id": [ { "id": "A0A9J7GND9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GND9", "type": "external" } ], "mass": 59259.0, "length": 510, "protein_name": "Cytosolic carboxypeptidase 6", "gene_name": "Agbl4", "organism": "Hamster", "refseq_name": "cytosolic carboxypeptidase 6", "refseq_ac": [ { "id": "XP_035294557", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294557", "type": "external" } ], "gene_names_uniprotkb": "Agbl4", "gene_names_refseq": "Agbl4", "protein_names_uniprotkb": "Cytosolic carboxypeptidase 6; 3.4.17.24; ATP/GTP-binding protein-like 4; Protein deglutamylase CCP6", "protein_names_refseq": "cytosolic carboxypeptidase 6", "tax_id": 10029, "disease": "", "pathway": " (cge:100759283)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 3% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Metallocarboxypeptidase that mediates protein deglutamylation of tubulin and non-tubulin target proteins. Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of tubulin protein. Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate. Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of non-tubulin proteins such as MYLK. Mediates the deglutamylation of nucleotidyltransferase CGAS, leading to CGAS antiviral defense response activation. Involved in KLF4 deglutamylation which promotes KLF4 proteasome-mediated degradation, thereby negatively regulating cell pluripotency maintenance and embryogenesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.4.17.24", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.17.24", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004181 metallocarboxypeptidase activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0005814 centriole", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GND9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GNE0-1", "uniprot_id": [ { "id": "A0A9J7GNE0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GNE0", "type": "external" } ], "mass": 151450.0, "length": 1365, "protein_name": "Kinesin-like protein KIF24", "gene_name": "Kif24", "organism": "Hamster", "refseq_name": "kinesin-like protein KIF24 isoform X2", "refseq_ac": [ { "id": "XP_035295813", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295813", "type": "external" } ], "gene_names_uniprotkb": "Kif24", "gene_names_refseq": "Kif24", "protein_names_uniprotkb": "Kinesin-like protein KIF24", "protein_names_refseq": "kinesin-like protein KIF24 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100770944)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Microtubule-dependent motor protein that acts as a negative regulator of ciliogenesis by mediating recruitment of CCP110 to mother centriole in cycling cells, leading to restrict nucleation of cilia at centrioles. Mediates depolymerization of microtubules of centriolar origin, possibly to suppress aberrant cilia formation. Following activation by NEK2 involved in disassembly of primary cilium during G2/M phase but does not disassemble fully formed ciliary axonemes. As cilium assembly and disassembly is proposed to coexist in a dynamic equilibrium may suppress nascent cilium assembly and, potentially, ciliar re-assembly in cells that have already disassembled their cilia ensuring the completion of cilium removal in the later stages of the cell cycle. Plays an important role in recruiting MPHOSPH9, a negative regulator of cilia formation to the distal end of mother centriole., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0003777 microtubule motor activity", "go_cellular_component": "GO:0005874 microtubule;GO:0005814 centriole", "go_biological_process": "GO:0007018 microtubule-based movement;GO:0030030 cell projection organization;GO:0007019 microtubule depolymerization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GNE0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GNE3-1", "uniprot_id": [ { "id": "A0A9J7GNE3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GNE3", "type": "external" } ], "mass": 329220.0, "length": 3020, "protein_name": "Adhesion G-protein coupled receptor G4", "gene_name": "Adgrg4", "organism": "Hamster", "refseq_name": "adhesion G-protein coupled receptor G4 isoform X2", "refseq_ac": [ { "id": "XP_027289199", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289199", "type": "external" } ], "gene_names_uniprotkb": "Adgrg4", "gene_names_refseq": "Adgrg4", "protein_names_uniprotkb": "Adhesion G-protein coupled receptor G4; G-protein coupled receptor 112", "protein_names_refseq": "adhesion G-protein coupled receptor G4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767655)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Orphan adhesion G-protein coupled receptor (aGPCR). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. ADGRG4 is coupled to G(s) G proteins and mediates activation of adenylate cyclase activity. May be act as sensor of mechanical forces., [UniProtKB, UniProtKB]", "predicted_glycosites": 7, "predicted_n_glycosites": 0, "predicted_o_glycosites": 7, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GNE3-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GNF5-1", "uniprot_id": [ { "id": "A0A9J7GNF5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GNF5", "type": "external" } ], "mass": 128010.0, "length": 1161, "protein_name": "Zinc finger protein ZFPM2", "gene_name": "Zfpm2", "organism": "Hamster", "refseq_name": "zinc finger protein ZFPM2 isoform X2", "refseq_ac": [ { "id": "XP_027287265", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287265", "type": "external" } ], "gene_names_uniprotkb": "Zfpm2", "gene_names_refseq": "Zfpm2", "protein_names_uniprotkb": "Zinc finger protein ZFPM2; Friend of GATA protein 2; Zinc finger protein multitype 2", "protein_names_refseq": "zinc finger protein ZFPM2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100768050)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048603.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Transcription regulator that plays a central role in heart morphogenesis and development of coronary vessels from epicardium, by regulating genes that are essential during cardiogenesis. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA4, GATA5 and GATA6. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. Also required in gonadal differentiation, possibly be regulating expression of SRY. Probably acts a corepressor of NR2F2., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0003714 transcription corepressor activity;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005654 nucleoplasm", "go_biological_process": "GO:0003192 mitral valve formation;GO:0003195 tricuspid valve formation;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GNF5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GNF9-1", "uniprot_id": [ { "id": "A0A9J7GNF9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GNF9", "type": "external" } ], "mass": 82575.0, "length": 760, "protein_name": "Delta-like protein", "gene_name": "Dll1", "organism": "Hamster", "refseq_name": "delta-like protein 1", "refseq_ac": [ { "id": "XP_035294663", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294663", "type": "external" } ], "gene_names_uniprotkb": "Dll1", "gene_names_refseq": "Dll1", "protein_names_uniprotkb": "Delta-like protein", "protein_names_refseq": "delta-like protein 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100750697)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 5% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Putative Notch ligand involved in the mediation of Notch signaling., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0005112 Notch binding", "go_cellular_component": "GO:0005912 adherens junction;GO:0045121 membrane raft;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0007219 Notch signaling pathway;GO:0030154 cell differentiation;GO:0045747 positive regulation of Notch signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GNF9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GNL0-1", "uniprot_id": [ { "id": "A0A9J7GNL0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GNL0", "type": "external" } ], "mass": 58850.0, "length": 544, "protein_name": "Alkaline phosphatase", "gene_name": "LOC113833527", "organism": "Hamster", "refseq_name": "alkaline phosphatase, germ cell type-like", "refseq_ac": [ { "id": "XP_035294745", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294745", "type": "external" } ], "gene_names_uniprotkb": "LOC113833527", "gene_names_refseq": "LOC113833527", "protein_names_uniprotkb": "Alkaline phosphatase; 3.1.3.1", "protein_names_refseq": "alkaline phosphatase, germ cell type-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113833527)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" } ], "go_molecular_function": "GO:0004035 alkaline phosphatase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0098552 side of membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GNL0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GNL4-1", "uniprot_id": [ { "id": "A0A9J7GNL4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GNL4", "type": "external" } ], "mass": 120556.0, "length": 1074, "protein_name": "Semaphorin-5A", "gene_name": "Sema5a", "organism": "Hamster", "refseq_name": "semaphorin-5A isoform X2", "refseq_ac": [ { "id": "XP_035295050", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295050", "type": "external" } ], "gene_names_uniprotkb": "Sema5a", "gene_names_refseq": "Sema5a", "protein_names_uniprotkb": "Semaphorin-5A; Semaphorin-F", "protein_names_refseq": "semaphorin-5A isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756526)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Bifunctional axonal guidance cue regulated by sulfated proteoglycans; attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs). Ligand for receptor PLXNB3. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030215 semaphorin receptor binding;GO:0045499 chemorepellent activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:1990256 signal clustering;GO:0030335 positive regulation of cell migration;GO:0071526 semaphorin-plexin signaling pathway;GO:0001755 neural crest cell migration;GO:0007411 axon guidance", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GNL4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GNM0-1", "uniprot_id": [ { "id": "A0A9J7GNM0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GNM0", "type": "external" } ], "mass": 21521.0, "length": 182, "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase", "gene_name": "Hacd4", "organism": "Hamster", "refseq_name": "very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4", "refseq_ac": [ { "id": "XP_035294542", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294542", "type": "external" } ], "gene_names_uniprotkb": "Hacd4", "gene_names_refseq": "Hacd4", "protein_names_uniprotkb": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; 4.2.1.134", "protein_names_refseq": "very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4", "tax_id": 10029, "disease": "", "pathway": " (cge:100774830)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613640.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.2.1.134", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.134", "type": "external" } ], "go_molecular_function": "GO:0102158 very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0030148 sphingolipid biosynthetic process;GO:0030497 fatty acid elongation;GO:0042761 very long-chain fatty acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GNM0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GNN1-1", "uniprot_id": [ { "id": "A0A9J7GNN1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GNN1", "type": "external" } ], "mass": 69206.0, "length": 634, "protein_name": "Chloride channel protein", "gene_name": "LOC100753449", "organism": "Hamster", "refseq_name": "chloride channel protein ClC-Ka isoform X2", "refseq_ac": [ { "id": "XP_035294775", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294775", "type": "external" } ], "gene_names_uniprotkb": "LOC100753449", "gene_names_refseq": "LOC100753449", "protein_names_uniprotkb": "Chloride channel protein", "protein_names_refseq": "chloride channel protein ClC-Ka isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100753449)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0005247 voltage-gated chloride channel activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane;GO:0034707 chloride channel complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GNN1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GNR2-1", "uniprot_id": [ { "id": "A0A9J7GNR2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GNR2", "type": "external" } ], "mass": 104289.0, "length": 920, "protein_name": "Tyrosine-protein phosphatase non-receptor type", "gene_name": "Ptpn3", "organism": "Hamster", "refseq_name": "tyrosine-protein phosphatase non-receptor type 3 isoform X1", "refseq_ac": [ { "id": "XP_035295762", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295762", "type": "external" } ], "gene_names_uniprotkb": "Ptpn3", "gene_names_refseq": "Ptpn3", "protein_names_uniprotkb": "Tyrosine-protein phosphatase non-receptor type; 3.1.3.48", "protein_names_refseq": "tyrosine-protein phosphatase non-receptor type 3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100765227)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May act at junctions between the membrane and the cytoskeleton., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" } ], "go_molecular_function": "GO:0008092 cytoskeletal protein binding;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GNR2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GNU6-1", "uniprot_id": [ { "id": "A0A9J7GNU6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GNU6", "type": "external" } ], "mass": 107502.0, "length": 979, "protein_name": "Anion exchange protein", "gene_name": "Slc4a9", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: anion exchange protein 4 isoform X3", "refseq_ac": [ { "id": "XP_035296082", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035296082", "type": "external" } ], "gene_names_uniprotkb": "Slc4a9", "gene_names_refseq": "Slc4a9", "protein_names_uniprotkb": "Anion exchange protein", "protein_names_refseq": "LOW QUALITY PROTEIN: anion exchange protein 4 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100752461)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Electroneutral Cl(-)/HCO3(-) antiporter that favors chloride ion entry and efflux of hydrogencarbonate and sodium ion across the basolateral membrane and may participate in salivary secretion. Also mediates Cl(-)/HCO3(-) exchange activity in the presence of K(+) as well as Cs(+), Li(+), and Rb(+). Does not contribute to Cl(-)/HCO3(-) exchanger in the apical membrane of the upper villous epithelium., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008510 sodium:bicarbonate symporter activity;GO:0140900 chloride:bicarbonate antiporter activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0051453 regulation of intracellular pH", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GNU6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GNU9-1", "uniprot_id": [ { "id": "A0A9J7GNU9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GNU9", "type": "external" } ], "mass": 27262.0, "length": 244, "protein_name": "Tubulin-folding cofactor B", "gene_name": "Tbcb", "organism": "Hamster", "refseq_name": "tubulin-folding cofactor B isoform X1", "refseq_ac": [ { "id": "XP_007644242", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644242", "type": "external" } ], "gene_names_uniprotkb": "Tbcb", "gene_names_refseq": "Tbcb", "protein_names_uniprotkb": "Tubulin-folding cofactor B; Cytoskeleton-associated protein 1; Cytoskeleton-associated protein CKAPI; Tubulin-specific chaperone B", "protein_names_refseq": "tubulin-folding cofactor B isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100770447)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 330 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614167.1) and transcript sequence (IACG01089209.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007644242.2. COMPLETENESS: full length., [RefSeq]; Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer. Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051010 microtubule plus-end binding;GO:0043014 alpha-tubulin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005938 cell cortex;GO:0035371 microtubule plus-end", "go_biological_process": "GO:0007399 nervous system development;GO:0030154 cell differentiation;GO:0007021 tubulin complex assembly;GO:0031122 cytoplasmic microtubule organization;GO:0007023 post-chaperonin tubulin folding pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GNU9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GPX7-1", "uniprot_id": [ { "id": "A0A9J7GPX7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GPX7", "type": "external" } ], "mass": 62721.0, "length": 539, "protein_name": "25/26-hydroxycholesterol 7alpha-hydroxylase", "gene_name": "LOC100754734", "organism": "Hamster", "refseq_name": "25-hydroxycholesterol 7-alpha-hydroxylase isoform X1", "refseq_ac": [ { "id": "XP_035295846", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295846", "type": "external" } ], "gene_names_uniprotkb": "LOC100754734", "gene_names_refseq": "LOC100754734", "protein_names_uniprotkb": "25/26-hydroxycholesterol 7alpha-hydroxylase; 1.14.14.29; Hippocampal transcript 1 protein; Oxysterol 7-alpha-hydroxylase", "protein_names_refseq": "25-hydroxycholesterol 7-alpha-hydroxylase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100754734)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008396 oxysterol 7-alpha-hydroxylase activity;GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0033783 25-hydroxycholesterol 7-alpha-hydroxylase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006699 bile acid biosynthetic process;GO:0008203 cholesterol metabolic process;GO:0042632 cholesterol homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GPX7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GNZ1-1", "uniprot_id": [ { "id": "A0A9J7GNZ1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GNZ1", "type": "external" } ], "mass": 85765.0, "length": 767, "protein_name": "Kinesin-like protein", "gene_name": "Kif17", "organism": "Hamster", "refseq_name": "kinesin-like protein KIF17 isoform X2", "refseq_ac": [ { "id": "XP_035295374", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295374", "type": "external" } ], "gene_names_uniprotkb": "Kif17", "gene_names_refseq": "Kif17", "protein_names_uniprotkb": "Kinesin-like protein", "protein_names_refseq": "kinesin-like protein KIF17 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100757590)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0003777 microtubule motor activity", "go_cellular_component": "GO:0005874 microtubule", "go_biological_process": "GO:0007018 microtubule-based movement", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GNZ1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GPP3-1", "uniprot_id": [ { "id": "A0A9J7GPP3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GPP3", "type": "external" } ], "mass": 102819.0, "length": 952, "protein_name": "Espin", "gene_name": "LOC100755239", "organism": "Hamster", "refseq_name": "espin isoform X2", "refseq_ac": [ { "id": "XP_035295260", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295260", "type": "external" } ], "gene_names_uniprotkb": "LOC100755239", "gene_names_refseq": "LOC100755239", "protein_names_uniprotkb": "Espin; Ectoplasmic specialization protein", "protein_names_refseq": "espin isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100755239)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Multifunctional actin-bundling protein. Plays a major role in regulating the organization, dimension, dynamics and signaling capacities of the actin filament-rich microvilli in the mechanosensory and chemosensory cells. Required for the assembly and stabilization of the stereociliary parallel actin bundles. Plays a crucial role in the formation and maintenance of inner ear hair cell stereocilia. Involved in the elongation of actin in stereocilia. In extrastriolar hair cells, required for targeting MYO3B to stereocilia tips, and for regulation of stereocilia diameter and staircase formation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0043197 dendritic spine;GO:0005902 microvillus;GO:0032420 stereocilium", "go_biological_process": "GO:0051017 actin filament bundle assembly;GO:0007605 sensory perception of sound", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GPP3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GP41-1", "uniprot_id": [ { "id": "A0A9J7GP41_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GP41", "type": "external" } ], "mass": 38559.0, "length": 336, "protein_name": "LIM and senescent cell antigen-like-containing domain protein", "gene_name": "Lims2", "organism": "Hamster", "refseq_name": "LIM and senescent cell antigen-like-containing domain protein 2 isoform X3", "refseq_ac": [ { "id": "XP_035294952", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294952", "type": "external" } ], "gene_names_uniprotkb": "Lims2", "gene_names_refseq": "Lims2", "protein_names_uniprotkb": "LIM and senescent cell antigen-like-containing domain protein", "protein_names_refseq": "LIM and senescent cell antigen-like-containing domain protein 2 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100755311)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005911 cell-cell junction;GO:0005925 focal adhesion", "go_biological_process": "GO:0007229 integrin-mediated signaling pathway;GO:0098609 cell-cell adhesion;GO:1900026 positive regulation of substrate adhesion-dependent cell spreading;GO:0061351 neural precursor cell proliferation;GO:2000346 negative regulation of hepatocyte proliferation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GP41-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GP75-1", "uniprot_id": [ { "id": "A0A9J7GP75_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GP75", "type": "external" } ], "mass": 52551.0, "length": 469, "protein_name": "Mothers against decapentaplegic homolog", "gene_name": "LOC113838325", "organism": "Hamster", "refseq_name": "mothers against decapentaplegic homolog 1-like isoform X2", "refseq_ac": [ { "id": "XP_027289890", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289890", "type": "external" } ], "gene_names_uniprotkb": "LOC113838325", "gene_names_refseq": "LOC113838325", "protein_names_uniprotkb": "Mothers against decapentaplegic homolog; MAD homolog; Mothers against DPP homolog; SMAD family member", "protein_names_refseq": "mothers against decapentaplegic homolog 1-like isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:113838325)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027289890.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0070411 I-SMAD binding", "go_cellular_component": "GO:0071144 heteromeric SMAD protein complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0030509 BMP signaling pathway;GO:0060395 SMAD protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7GP75-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GPD0-1", "uniprot_id": [ { "id": "A0A9J7GPD0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GPD0", "type": "external" } ], "mass": 159920.0, "length": 1423, "protein_name": "RNA uridylyltransferase", "gene_name": "LOC103158637", "organism": "Hamster", "refseq_name": "terminal uridylyltransferase 4 isoform X2", "refseq_ac": [ { "id": "XP_027290039", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027290039", "type": "external" } ], "gene_names_uniprotkb": "LOC103158637", "gene_names_refseq": "LOC103158637", "protein_names_uniprotkb": "RNA uridylyltransferase; 2.7.7.52", "protein_names_refseq": "terminal uridylyltransferase 4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:103158637)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023277308.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027290039.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.52", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.52", "type": "external" }, { "id": "2.7.7.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.19", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003676 nucleic acid binding;GO:0050265 RNA uridylyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0001556 oocyte maturation;GO:0010586 miRNA metabolic process;GO:0031123 RNA 3'-end processing;GO:1990074 polyuridylation-dependent mRNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7GPD0-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GPE5-1", "uniprot_id": [ { "id": "A0A9J7GPE5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GPE5", "type": "external" } ], "mass": 50337.0, "length": 449, "protein_name": "Mothers against decapentaplegic homolog", "gene_name": "LOC113830754", "organism": "Hamster", "refseq_name": "mothers against decapentaplegic homolog 1-like", "refseq_ac": [ { "id": "XP_027289886", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289886", "type": "external" } ], "gene_names_uniprotkb": "LOC113830754", "gene_names_refseq": "LOC113830754", "protein_names_uniprotkb": "Mothers against decapentaplegic homolog; MAD homolog; Mothers against DPP homolog; SMAD family member", "protein_names_refseq": "mothers against decapentaplegic homolog 1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113830754)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027289886.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0070411 I-SMAD binding", "go_cellular_component": "GO:0071144 heteromeric SMAD protein complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0030509 BMP signaling pathway;GO:0060395 SMAD protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7GPE5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GPI3-1", "uniprot_id": [ { "id": "A0A9J7GPI3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GPI3", "type": "external" } ], "mass": 32103.0, "length": 287, "protein_name": "SMAD family member 1", "gene_name": "LOC113838875", "organism": "Hamster", "refseq_name": "mothers against decapentaplegic homolog 1-like", "refseq_ac": [ { "id": "XP_027290179", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027290179", "type": "external" } ], "gene_names_uniprotkb": "LOC113838875", "gene_names_refseq": "LOC113838875", "protein_names_uniprotkb": "SMAD family member 1; Mothers against decapentaplegic homolog 1", "protein_names_refseq": "mothers against decapentaplegic homolog 1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113838875)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 100% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276935.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: incomplete on the carboxy end., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0070411 I-SMAD binding", "go_cellular_component": "GO:0071144 heteromeric SMAD protein complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0030509 BMP signaling pathway;GO:0060395 SMAD protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7GPI3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GPI4-1", "uniprot_id": [ { "id": "A0A9J7GPI4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GPI4", "type": "external" } ], "mass": 52481.0, "length": 467, "protein_name": "Mothers against decapentaplegic homolog", "gene_name": "LOC113830739", "organism": "Hamster", "refseq_name": "mothers against decapentaplegic homolog 1 isoform X1", "refseq_ac": [ { "id": "XP_027290005", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027290005", "type": "external" } ], "gene_names_uniprotkb": "LOC113830739", "gene_names_refseq": "LOC113830739", "protein_names_uniprotkb": "Mothers against decapentaplegic homolog; MAD homolog; Mothers against DPP homolog; SMAD family member", "protein_names_refseq": "mothers against decapentaplegic homolog 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:113830739)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0070411 I-SMAD binding", "go_cellular_component": "GO:0071144 heteromeric SMAD protein complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0030509 BMP signaling pathway;GO:0060395 SMAD protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7GPI4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GPJ5-1", "uniprot_id": [ { "id": "A0A9J7GPJ5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GPJ5", "type": "external" } ], "mass": 52574.0, "length": 467, "protein_name": "Mothers against decapentaplegic homolog", "gene_name": "LOC113838655", "organism": "Hamster", "refseq_name": "mothers against decapentaplegic homolog 1-like", "refseq_ac": [ { "id": "XP_027290038", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027290038", "type": "external" } ], "gene_names_uniprotkb": "LOC113838655", "gene_names_refseq": "LOC113838655", "protein_names_uniprotkb": "Mothers against decapentaplegic homolog; MAD homolog; Mothers against DPP homolog; SMAD family member", "protein_names_refseq": "mothers against decapentaplegic homolog 1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113838655)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276860.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0070411 I-SMAD binding", "go_cellular_component": "GO:0071144 heteromeric SMAD protein complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0030509 BMP signaling pathway;GO:0060395 SMAD protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7GPJ5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GPQ3-1", "uniprot_id": [ { "id": "A0A9J7GPQ3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GPQ3", "type": "external" } ], "mass": 34539.0, "length": 311, "protein_name": "Serine/threonine-protein kinase", "gene_name": "Pim2", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase pim-2", "refseq_ac": [ { "id": "XP_003505144", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505144", "type": "external" } ], "gene_names_uniprotkb": "Pim2", "gene_names_refseq": "Pim2", "protein_names_uniprotkb": "Serine/threonine-protein kinase; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase pim-2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762236)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614122.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0006915 apoptotic process;GO:0007346 regulation of mitotic cell cycle;GO:0050821 protein stabilization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GPQ3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GPT6-1", "uniprot_id": [ { "id": "A0A9J7GPT6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GPT6", "type": "external" } ], "mass": 213966.0, "length": 1846, "protein_name": "Unconventional myosin-Vb", "gene_name": "Myo5b", "organism": "Hamster", "refseq_name": "unconventional myosin-Vb isoform X2", "refseq_ac": [ { "id": "XP_035294606", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294606", "type": "external" } ], "gene_names_uniprotkb": "Myo5b", "gene_names_refseq": "Myo5b", "protein_names_uniprotkb": "Unconventional myosin-Vb", "protein_names_refseq": "unconventional myosin-Vb isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100765544)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A participates in epithelial cell polarization. Together with RAB25 regulates transcytosis. Required for proper localization of bile salt export pump ABCB11 at the apical/canalicular plasma membrane of hepatocytes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0019899 enzyme binding;GO:0051015 actin filament binding;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0016020 membrane;GO:0043025 neuronal cell body;GO:0031410 cytoplasmic vesicle;GO:0016459 myosin complex;GO:0098685 Schaffer collateral - CA1 synapse", "go_biological_process": "GO:0007015 actin filament organization;GO:0015031 protein transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GPT6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GQ10-1", "uniprot_id": [ { "id": "A0A9J7GQ10_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GQ10", "type": "external" } ], "mass": 462695.0, "length": 4042, "protein_name": "Dynein axonemal heavy chain 7", "gene_name": "Dnah7", "organism": "Hamster", "refseq_name": "dynein heavy chain 7, axonemal isoform X2", "refseq_ac": [ { "id": "XP_035294723", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294723", "type": "external" } ], "gene_names_uniprotkb": "Dnah7", "gene_names_refseq": "Dnah7", "protein_names_uniprotkb": "Dynein axonemal heavy chain 7; Axonemal beta dynein heavy chain 7; Ciliary dynein heavy chain 7", "protein_names_refseq": "dynein heavy chain 7, axonemal isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100752773)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0005509 calcium ion binding;GO:0008569 minus-end-directed microtubule motor activity;GO:0051959 dynein light intermediate chain binding;GO:0045505 dynein intermediate chain binding", "go_cellular_component": "GO:0005874 microtubule;GO:0031514 motile cilium;GO:0005858 axonemal dynein complex", "go_biological_process": "GO:0007018 microtubule-based movement", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GQ10-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GQ42-1", "uniprot_id": [ { "id": "A0A9J7GQ42_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GQ42", "type": "external" } ], "mass": 162666.0, "length": 1500, "protein_name": "Mitogen-activated protein kinase kinase kinase 1", "gene_name": "Map3k1", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: mitogen-activated protein kinase kinase kinase 1 isoform X2", "refseq_ac": [ { "id": "XP_035294675", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294675", "type": "external" } ], "gene_names_uniprotkb": "Map3k1", "gene_names_refseq": "Map3k1", "protein_names_uniprotkb": "Mitogen-activated protein kinase kinase kinase 1; 2.7.11.25; MAPK/ERK kinase kinase 1", "protein_names_refseq": "LOW QUALITY PROTEIN: mitogen-activated protein kinase kinase kinase 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100770540)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 2 indels ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: incomplete on the amino end., [RefSeq]; Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. May phosphorylate the MAPK8/JNK1 kinase. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0004706 JUN kinase kinase kinase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0110053 regulation of actin filament organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GQ42-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GQ65-1", "uniprot_id": [ { "id": "A0A9J7GQ65_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GQ65", "type": "external" } ], "mass": 38351.0, "length": 337, "protein_name": "Rhomboid-related protein 4", "gene_name": "LOC100756292", "organism": "Hamster", "refseq_name": "rhomboid-related protein 4 isoform X4", "refseq_ac": [ { "id": "XP_035296949", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035296949", "type": "external" } ], "gene_names_uniprotkb": "LOC100756292", "gene_names_refseq": "LOC100756292", "protein_names_uniprotkb": "Rhomboid-related protein 4; 3.4.21.105; Rhomboid domain-containing protein 1; Rhomboid-like protein 4", "protein_names_refseq": "rhomboid-related protein 4 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100756292)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0031966 mitochondrial membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0043066 negative regulation of apoptotic process;GO:0051247 positive regulation of protein metabolic process;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GQ65-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GQA2-1", "uniprot_id": [ { "id": "A0A9J7GQA2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GQA2", "type": "external" } ], "mass": 104385.0, "length": 912, "protein_name": "Cullin-4B", "gene_name": "Cul4b", "organism": "Hamster", "refseq_name": "cullin-4B isoform X2", "refseq_ac": [ { "id": "XP_027289344", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289344", "type": "external" } ], "gene_names_uniprotkb": "Cul4b", "gene_names_refseq": "Cul4b", "protein_names_uniprotkb": "Cullin-4B", "protein_names_refseq": "cullin-4B isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763989)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0031464 Cul4A-RING E3 ubiquitin ligase complex;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0031465 Cul4B-RING E3 ubiquitin ligase complex", "go_biological_process": "GO:0006281 DNA repair;GO:0042254 ribosome biogenesis;GO:0016567 protein ubiquitination;GO:1900087 positive regulation of G1/S transition of mitotic cell cycle;GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GQA2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GQG9-1", "uniprot_id": [ { "id": "A0A9J7GQG9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GQG9", "type": "external" } ], "mass": 215067.0, "length": 1918, "protein_name": "Receptor-type tyrosine-protein phosphatase delta", "gene_name": "Ptprd", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase delta isoform X8", "refseq_ac": [ { "id": "XP_035294848", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294848", "type": "external" } ], "gene_names_uniprotkb": "Ptprd", "gene_names_refseq": "Ptprd", "protein_names_uniprotkb": "Receptor-type tyrosine-protein phosphatase delta; 3.1.3.48", "protein_names_refseq": "LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase delta isoform X8", "tax_id": 10029, "disease": "", "pathway": " (cge:100760691)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 6 indels internal stop codons :: corrected 2 genomic stop codons ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Can bidirectionally induce pre- and post-synaptic differentiation of neurons by mediating interaction with IL1RAP and IL1RAPL1 trans-synaptically. Involved in pre-synaptic differentiation through interaction with SLITRK2., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" } ], "go_molecular_function": "GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0042734 presynaptic membrane", "go_biological_process": "GO:0099054 presynapse assembly;GO:0010975 regulation of neuron projection development;GO:0099560 synaptic membrane adhesion;GO:0099151 regulation of postsynaptic density assembly;GO:0099537 trans-synaptic signaling", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GQG9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O35080-1", "uniprot_id": [ { "id": "O35080_CRIGR", "url": "https://www.uniprot.org/uniprot/O35080", "type": "external" } ], "mass": 116671.0, "length": 1038, "protein_name": "Polyubiquitin-C", "gene_name": "Ubc", "organism": "Hamster", "refseq_name": "polyubiquitin-C", "refseq_ac": [ { "id": "NP_001231307", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231307", "type": "external" } ], "gene_names_uniprotkb": "Ubc; Chub2; Ubiquitin", "gene_names_refseq": "Chub2; Ubc; Ubiquitin", "protein_names_uniprotkb": "Polyubiquitin-C", "protein_names_refseq": "polyubiquitin-C; polyubiquitin", "tax_id": 10029, "disease": "", "pathway": " (cge:100689267)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "29704459;32410221;9504932", "class_list": "", "function": "PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB003732.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "O35080-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9EQS1-1", "uniprot_id": [ { "id": "Q9EQS1_CRIGR", "url": "https://www.uniprot.org/uniprot/Q9EQS1", "type": "external" } ], "mass": 68270.0, "length": 622, "protein_name": "Fanconi anemia group G protein", "gene_name": "Fancg", "organism": "Hamster", "refseq_name": "Fanconi anemia group G protein", "refseq_ac": [ { "id": "NP_001231323", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231323", "type": "external" } ], "gene_names_uniprotkb": "Fancg; Xrcc9", "gene_names_refseq": "Fancg; Xrcc9", "protein_names_uniprotkb": "Fanconi anemia group G protein", "protein_names_refseq": "Fanconi anemia complementation group G; Fanconi anemia group G protein", "tax_id": 10029, "disease": "", "pathway": " (cge:100689273)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "21945585;29704459;32410221", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMN04501028, SAMN04501029 [ECO:0000350] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC084885.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0043240 Fanconi anaemia nuclear complex", "go_biological_process": "GO:0036297 interstrand cross-link repair", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9EQS1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QHQ6-1", "uniprot_id": [ { "id": "A0A8C2QHQ6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QHQ6", "type": "external" } ], "mass": 38490.0, "length": 357, "protein_name": "cAMP-responsive element modulator", "gene_name": "Crem", "organism": "Hamster", "refseq_name": "cAMP-responsive element modulator isoform X2", "refseq_ac": [ { "id": "XP_007645315", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645315", "type": "external" } ], "gene_names_uniprotkb": "Crem", "gene_names_refseq": "Crem", "protein_names_uniprotkb": "cAMP-responsive element modulator", "protein_names_refseq": "cAMP-responsive element modulator isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767867)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614263.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific", "go_cellular_component": "GO:1990589 ATF4-CREB1 transcription factor complex;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QHQ6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QMC2-1", "uniprot_id": [ { "id": "A0A8C2QMC2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QMC2", "type": "external" } ], "mass": 14107.0, "length": 128, "protein_name": "Prokineticin-2", "gene_name": "Prok2", "organism": "Hamster", "refseq_name": "prokineticin-2 isoform X2", "refseq_ac": [ { "id": "XP_027284642", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284642", "type": "external" } ], "gene_names_uniprotkb": "Prok2", "gene_names_refseq": "Prok2", "protein_names_uniprotkb": "Prokineticin-2", "protein_names_refseq": "prokineticin-2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100759658)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May function as an output molecule from the suprachiasmatic nucleus (SCN) that transmits behavioral circadian rhythm. May also function locally within the SCN to synchronize output. Potently contracts gastrointestinal (GI) smooth muscle., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001664 G protein-coupled receptor binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0001525 angiogenesis;GO:0006935 chemotaxis;GO:0007218 neuropeptide signaling pathway;GO:0007283 spermatogenesis;GO:0043066 negative regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QMC2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QEM0-1", "uniprot_id": [ { "id": "A0A8C2QEM0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QEM0", "type": "external" } ], "mass": 70242.0, "length": 637, "protein_name": "Polyadenylate-binding protein", "gene_name": "LOC100751841", "organism": "Hamster", "refseq_name": "polyadenylate-binding protein 1", "refseq_ac": [ { "id": "XP_003500517", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500517", "type": "external" } ], "gene_names_uniprotkb": "LOC100751841", "gene_names_refseq": "LOC100751841", "protein_names_uniprotkb": "Polyadenylate-binding protein; PABP", "protein_names_refseq": "polyadenylate-binding protein 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100751841)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613794.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Binds the poly(A) tail of mRNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0030027 lamellipodium;GO:0005681 spliceosomal complex;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0008380 RNA splicing;GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QEM0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QEM1-1", "uniprot_id": [ { "id": "A0A8C2QEM1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QEM1", "type": "external" } ], "mass": 116265.0, "length": 1047, "protein_name": "ubiquitinyl hydrolase 1", "gene_name": "Usp38", "organism": "Hamster", "refseq_name": "ubiquitin carboxyl-terminal hydrolase 38 isoform X2", "refseq_ac": [ { "id": "XP_027260674", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260674", "type": "external" } ], "gene_names_uniprotkb": "Usp38", "gene_names_refseq": "Usp38", "protein_names_uniprotkb": "ubiquitinyl hydrolase 1; 3.4.19.12", "protein_names_refseq": "ubiquitin carboxyl-terminal hydrolase 38 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100753531)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0006511 ubiquitin-dependent protein catabolic process;GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0045824 negative regulation of innate immune response;GO:1990168 protein K33-linked deubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QEM1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QEM5-1", "uniprot_id": [ { "id": "A0A8C2QEM5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QEM5", "type": "external" } ], "mass": 35920.0, "length": 367, "protein_name": "Class E basic helix-loop-helix protein 22", "gene_name": "LOC113834412", "organism": "Hamster", "refseq_name": "class E basic helix-loop-helix protein 22", "refseq_ac": [ { "id": "XP_027259282", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259282", "type": "external" } ], "gene_names_uniprotkb": "LOC113834412", "gene_names_refseq": "LOC113834412", "protein_names_uniprotkb": "Class E basic helix-loop-helix protein 22; Class B basic helix-loop-helix protein 5", "protein_names_refseq": "class E basic helix-loop-helix protein 22", "tax_id": 10029, "disease": "", "pathway": " (cge:113834412)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0070888 E-box binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0060042 retina morphogenesis in camera-type eye;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0061564 axon development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QEM5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QEM8-1", "uniprot_id": [ { "id": "A0A8C2QEM8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QEM8", "type": "external" } ], "mass": 34976.0, "length": 310, "protein_name": "Olfactory receptor", "gene_name": "LOC100762859", "organism": "Hamster", "refseq_name": "olfactory receptor 145", "refseq_ac": [ { "id": "XP_007651866", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651866", "type": "external" } ], "gene_names_uniprotkb": "LOC100762859", "gene_names_refseq": "LOC100762859", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 145", "tax_id": 10029, "disease": "", "pathway": " (cge:100762859)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615884.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Odorant receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QEM8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QEM9-1", "uniprot_id": [ { "id": "A0A8C2QEM9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QEM9", "type": "external" } ], "mass": 35283.0, "length": 321, "protein_name": "Olfactory receptor", "gene_name": "LOC100760272; LOC100763724", "organism": "Hamster", "refseq_name": "olfactory receptor 10C1-like isoform X3", "refseq_ac": [ { "id": "XP_027255809", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255809", "type": "external" } ], "gene_names_uniprotkb": "LOC100760272; LOC100763724", "gene_names_refseq": "LOC100760272", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 10C1-like isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100760272); (cge:100763724)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QEM9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QEN1-1", "uniprot_id": [ { "id": "A0A8C2QEN1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QEN1", "type": "external" } ], "mass": 49885.0, "length": 441, "protein_name": "Zinc finger and BTB domain-containing protein 8A", "gene_name": "Zbtb8a", "organism": "Hamster", "refseq_name": "zinc finger and BTB domain-containing protein 8A", "refseq_ac": [ { "id": "XP_027255181", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255181", "type": "external" } ], "gene_names_uniprotkb": "Zbtb8a", "gene_names_refseq": "Zbtb8a", "protein_names_uniprotkb": "Zinc finger and BTB domain-containing protein 8A", "protein_names_refseq": "zinc finger and BTB domain-containing protein 8A", "tax_id": 10029, "disease": "", "pathway": " (cge:100751842)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001223 transcription coactivator binding;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QEN1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QEN3-1", "uniprot_id": [ { "id": "A0A8C2QEN3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QEN3", "type": "external" } ], "mass": 11640.0, "length": 105, "protein_name": "Cytochrome c, testis-specific", "gene_name": "LOC100764460", "organism": "Hamster", "refseq_name": "cytochrome c, testis-specific", "refseq_ac": [ { "id": "XP_003501062", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501062", "type": "external" } ], "gene_names_uniprotkb": "LOC100764460", "gene_names_refseq": "LOC100764460", "protein_names_uniprotkb": "Cytochrome c, testis-specific", "protein_names_refseq": "cytochrome c, testis-specific", "tax_id": 10029, "disease": "", "pathway": " (cge:100764460)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613827.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain., [UniProtKB, UniProtKB, UniProtKB]; Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0009055 electron transfer activity;GO:0046872 metal ion binding;GO:0020037 heme binding", "go_cellular_component": "GO:0005758 mitochondrial intermembrane space", "go_biological_process": "GO:0022904 respiratory electron transport chain", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QEN3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QEQ7-1", "uniprot_id": [ { "id": "A0A8C2QEQ7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QEQ7", "type": "external" } ], "mass": 7894.0, "length": 76, "protein_name": "Signal transducer CD24", "gene_name": "Cd24", "organism": "Hamster", "refseq_name": "signal transducer CD24", "refseq_ac": [ { "id": "XP_003497022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497022", "type": "external" } ], "gene_names_uniprotkb": "Cd24", "gene_names_refseq": "Cd24", "protein_names_uniprotkb": "Signal transducer CD24", "protein_names_refseq": "signal transducer CD24", "tax_id": 10029, "disease": "", "pathway": " (cge:100767726)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613639.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030296 protein tyrosine kinase activator activity", "go_cellular_component": "GO:0045121 membrane raft;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0007155 cell adhesion;GO:0022407 regulation of cell-cell adhesion;GO:0001775 cell activation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QEQ7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QER1-1", "uniprot_id": [ { "id": "A0A8C2QER1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QER1", "type": "external" } ], "mass": 157240.0, "length": 1376, "protein_name": "Mediator of RNA polymerase II transcription subunit 23", "gene_name": "Med23", "organism": "Hamster", "refseq_name": "mediator of RNA polymerase II transcription subunit 23 isoform X1", "refseq_ac": [ { "id": "XP_003513138", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513138", "type": "external" } ], "gene_names_uniprotkb": "Med23", "gene_names_refseq": "Med23", "protein_names_uniprotkb": "Mediator of RNA polymerase II transcription subunit 23; Mediator complex subunit 23", "protein_names_refseq": "mediator of RNA polymerase II transcription subunit 23 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100775007)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615724.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005667 transcription regulator complex;GO:0016592 mediator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0010628 positive regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QER1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QEU0-1", "uniprot_id": [ { "id": "A0A8C2QEU0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QEU0", "type": "external" } ], "mass": 30382.0, "length": 284, "protein_name": "T-cell leukemia homeobox protein 2", "gene_name": "LOC113837067", "organism": "Hamster", "refseq_name": "T-cell leukemia homeobox protein 2", "refseq_ac": [ { "id": "XP_027285240", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285240", "type": "external" } ], "gene_names_uniprotkb": "LOC113837067", "gene_names_refseq": "LOC113837067", "protein_names_uniprotkb": "T-cell leukemia homeobox protein 2", "protein_names_refseq": "T-cell leukemia homeobox protein 2", "tax_id": 10029, "disease": "", "pathway": " (cge:113837067)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0048513 animal organ development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QEU0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QEU6-1", "uniprot_id": [ { "id": "A0A8C2QEU6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QEU6", "type": "external" } ], "mass": 15385.0, "length": 134, "protein_name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit P", "gene_name": "LOC100769454", "organism": "Hamster", "refseq_name": "phosphatidylinositol N-acetylglucosaminyltransferase subunit P", "refseq_ac": [ { "id": "XP_003515328", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003515328", "type": "external" } ], "gene_names_uniprotkb": "LOC100769454", "gene_names_refseq": "LOC100769454", "protein_names_uniprotkb": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit P", "protein_names_refseq": "phosphatidylinositol N-acetylglucosaminyltransferase subunit P", "tax_id": 10029, "disease": "", "pathway": " (cge:100769454)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003617687.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0006506 GPI anchor biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QEU6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QEV4-1", "uniprot_id": [ { "id": "A0A8C2QEV4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QEV4", "type": "external" } ], "mass": 83065.0, "length": 728, "protein_name": "small monomeric GTPase", "gene_name": "Cracr2a", "organism": "Hamster", "refseq_name": "EF-hand calcium-binding domain-containing protein 4B isoform X2", "refseq_ac": [ { "id": "XP_027284158", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284158", "type": "external" } ], "gene_names_uniprotkb": "Cracr2a", "gene_names_refseq": "Cracr2a", "protein_names_uniprotkb": "small monomeric GTPase; 3.6.5.2", "protein_names_refseq": "EF-hand calcium-binding domain-containing protein 4B isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763551)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0008104 intracellular protein localization;GO:0051928 positive regulation of calcium ion transport;GO:0002115 store-operated calcium entry", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QEV4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QEV8-1", "uniprot_id": [ { "id": "A0A8C2QEV8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QEV8", "type": "external" } ], "mass": 52085.0, "length": 459, "protein_name": "Sorting nexin-8", "gene_name": "Snx8", "organism": "Hamster", "refseq_name": "sorting nexin-8 isoform X3", "refseq_ac": [ { "id": "XP_027269307", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269307", "type": "external" } ], "gene_names_uniprotkb": "Snx8", "gene_names_refseq": "Snx8", "protein_names_uniprotkb": "Sorting nexin-8", "protein_names_refseq": "sorting nexin-8 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100769926)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in several stages of intracellular trafficking. May play a role in intracellular protein transport from early endosomes to the trans-Golgi network., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0035091 phosphatidylinositol binding", "go_cellular_component": "GO:0005829 cytosol;GO:0031901 early endosome membrane;GO:0030904 retromer complex", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0034498 early endosome to Golgi transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QEV8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QEY3-1", "uniprot_id": [ { "id": "A0A8C2QEY3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QEY3", "type": "external" } ], "mass": 34801.0, "length": 313, "protein_name": "Olfactory receptor", "gene_name": "LOC100761227", "organism": "Hamster", "refseq_name": "olfactory receptor 1020-like", "refseq_ac": [ { "id": "XP_007652149", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007652149", "type": "external" } ], "gene_names_uniprotkb": "LOC100761227", "gene_names_refseq": "LOC100761227", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1020-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100761227)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616095.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QEY3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QEY4-1", "uniprot_id": [ { "id": "A0A8C2QEY4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QEY4", "type": "external" } ], "mass": 35334.0, "length": 314, "protein_name": "Olfactory receptor", "gene_name": "LOC100768855", "organism": "Hamster", "refseq_name": "olfactory receptor 1", "refseq_ac": [ { "id": "XP_027281961", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281961", "type": "external" } ], "gene_names_uniprotkb": "LOC100768855", "gene_names_refseq": "LOC100768855", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100768855)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QEY4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QF00-1", "uniprot_id": [ { "id": "A0A8C2QF00_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QF00", "type": "external" } ], "mass": 28372.0, "length": 261, "protein_name": "LOW QUALITY PROTEIN: rho-related GTP-binding protein RhoU isoform X2", "gene_name": "Rhou", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: rho-related GTP-binding protein RhoU isoform X2", "refseq_ac": [ { "id": "XP_027260669", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260669", "type": "external" } ], "gene_names_uniprotkb": "Rhou", "gene_names_refseq": "Rhou", "protein_names_uniprotkb": "LOW QUALITY PROTEIN: rho-related GTP-binding protein RhoU isoform X2", "protein_names_refseq": "LOW QUALITY PROTEIN: rho-related GTP-binding protein RhoU isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100775019)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0030674 protein-macromolecule adaptor activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005925 focal adhesion", "go_biological_process": "GO:0007010 cytoskeleton organization;GO:0007264 small GTPase-mediated signal transduction;GO:0008360 regulation of cell shape;GO:0120183 positive regulation of focal adhesion disassembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QF00-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QF07-1", "uniprot_id": [ { "id": "A0A8C2QF07_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QF07", "type": "external" } ], "mass": 9369.0, "length": 84, "protein_name": "Protein myomixer-like", "gene_name": "LOC113831449", "organism": "Hamster", "refseq_name": "protein myomixer-like", "refseq_ac": [ { "id": "XP_027266155", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266155", "type": "external" } ], "gene_names_uniprotkb": "LOC113831449", "gene_names_refseq": "LOC113831449", "protein_names_uniprotkb": "Protein myomixer-like", "protein_names_refseq": "protein myomixer-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113831449)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0060538 skeletal muscle organ development;GO:0007520 myoblast fusion;GO:0045026 plasma membrane fusion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QF07-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QF17-1", "uniprot_id": [ { "id": "A0A8C2QF17_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QF17", "type": "external" } ], "mass": 35392.0, "length": 314, "protein_name": "Olfactory receptor", "gene_name": "LOC100766438", "organism": "Hamster", "refseq_name": "olfactory receptor 1 isoform X2", "refseq_ac": [ { "id": "XP_027281970", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281970", "type": "external" } ], "gene_names_uniprotkb": "LOC100766438", "gene_names_refseq": "LOC100766438", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100766438)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QF17-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QF26-1", "uniprot_id": [ { "id": "A0A8C2QF26_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QF26", "type": "external" } ], "mass": 56360.0, "length": 490, "protein_name": "[histone H3]-lysine(4) N-trimethyltransferase", "gene_name": "Smyd1", "organism": "Hamster", "refseq_name": "histone-lysine N-methyltransferase SMYD1 isoform X2", "refseq_ac": [ { "id": "XP_027285338", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285338", "type": "external" } ], "gene_names_uniprotkb": "Smyd1", "gene_names_refseq": "Smyd1", "protein_names_uniprotkb": "[histone H3]-lysine(4) N-trimethyltransferase; 2.1.1.354; SET and MYND domain-containing protein 1", "protein_names_refseq": "histone-lysine N-methyltransferase SMYD1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100766221)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.354", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.354", "type": "external" }, { "id": "2.1.1.359", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.359", "type": "external" }, { "id": "2.1.1.355", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.355", "type": "external" }, { "id": "2.1.1.362", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.362", "type": "external" }, { "id": "2.1.1.361", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.361", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0140999 histone H3K4 trimethyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QF26-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QF33-1", "uniprot_id": [ { "id": "A0A8C2QF33_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QF33", "type": "external" } ], "mass": 63152.0, "length": 579, "protein_name": "Glypican-2 isoform X2", "gene_name": "Gpc2", "organism": "Hamster", "refseq_name": "glypican-2 isoform X2", "refseq_ac": [ { "id": "XP_027268125", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268125", "type": "external" } ], "gene_names_uniprotkb": "Gpc2", "gene_names_refseq": "Gpc2", "protein_names_uniprotkb": "Glypican-2 isoform X2", "protein_names_refseq": "glypican-2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772009)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023277414.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cell surface proteoglycan., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0031012 extracellular matrix", "go_biological_process": "GO:0016477 cell migration;GO:0009966 regulation of signal transduction;GO:0007224 smoothened signaling pathway;GO:1905475 regulation of protein localization to membrane", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8C2QF33-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QF65-1", "uniprot_id": [ { "id": "A0A8C2QF65_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QF65", "type": "external" } ], "mass": 68901.0, "length": 629, "protein_name": "Nuclear receptor subfamily 2 group C member 2 isoform X1", "gene_name": "Nr2c2", "organism": "Hamster", "refseq_name": "nuclear receptor subfamily 2 group C member 2 isoform X1", "refseq_ac": [ { "id": "XP_027284692", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284692", "type": "external" } ], "gene_names_uniprotkb": "Nr2c2", "gene_names_refseq": "Nr2c2", "protein_names_uniprotkb": "Nuclear receptor subfamily 2 group C member 2 isoform X1", "protein_names_refseq": "nuclear receptor subfamily 2 group C member 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100766644)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003700 DNA-binding transcription factor activity;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0046330 positive regulation of JNK cascade;GO:0043123 positive regulation of canonical NF-kappaB signal transduction;GO:0033209 tumor necrosis factor-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QF65-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QF70-1", "uniprot_id": [ { "id": "A0A8C2QF70_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QF70", "type": "external" } ], "mass": 6267.0, "length": 53, "protein_name": "Small ribosomal subunit protein uS14", "gene_name": "LOC100756842", "organism": "Hamster", "refseq_name": "40S ribosomal protein S29-like", "refseq_ac": [ { "id": "XP_035297429", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297429", "type": "external" } ], "gene_names_uniprotkb": "LOC100756842", "gene_names_refseq": "LOC100756842", "protein_names_uniprotkb": "Small ribosomal subunit protein uS14; 40S ribosomal protein S29", "protein_names_refseq": "40S ribosomal protein S29-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100756842)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QF70-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QF85-1", "uniprot_id": [ { "id": "A0A8C2QF85_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QF85", "type": "external" } ], "mass": 17427.0, "length": 156, "protein_name": "60S ribosomal protein L29", "gene_name": "Rpl29", "organism": "Hamster", "refseq_name": "60S ribosomal protein L29 isoform X2", "refseq_ac": [ { "id": "XP_027270209", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270209", "type": "external" } ], "gene_names_uniprotkb": "Rpl29", "gene_names_refseq": "Rpl29", "protein_names_uniprotkb": "60S ribosomal protein L29", "protein_names_refseq": "60S ribosomal protein L29 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:103158593)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QF85-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QFA5-1", "uniprot_id": [ { "id": "A0A8C2QFA5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QFA5", "type": "external" } ], "mass": 19275.0, "length": 171, "protein_name": "Ly6/PLAUR domain-containing protein 6", "gene_name": "Lypd6", "organism": "Hamster", "refseq_name": "ly6/PLAUR domain-containing protein 6", "refseq_ac": [ { "id": "XP_003514037", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514037", "type": "external" } ], "gene_names_uniprotkb": "Lypd6", "gene_names_refseq": "Lypd6", "protein_names_uniprotkb": "Ly6/PLAUR domain-containing protein 6", "protein_names_refseq": "ly6/PLAUR domain-containing protein 6", "tax_id": 10029, "disease": "", "pathway": " (cge:100751619)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616264.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030550 acetylcholine receptor inhibitor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0098552 side of membrane", "go_biological_process": "GO:0090263 positive regulation of canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QFA5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QFB5-1", "uniprot_id": [ { "id": "A0A8C2QFB5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QFB5", "type": "external" } ], "mass": 35107.0, "length": 305, "protein_name": "Vomeronasal type-1 receptor", "gene_name": "LOC100764863", "organism": "Hamster", "refseq_name": "putative vomeronasal receptor-like protein 4", "refseq_ac": [ { "id": "XP_007643579", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643579", "type": "external" } ], "gene_names_uniprotkb": "LOC100764863", "gene_names_refseq": "LOC100764863", "protein_names_uniprotkb": "Vomeronasal type-1 receptor", "protein_names_refseq": "putative vomeronasal receptor-like protein 4", "tax_id": 10029, "disease": "", "pathway": " (cge:100764863)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614101.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016503 pheromone receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0019236 response to pheromone;GO:0007606 sensory perception of chemical stimulus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QFB5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QFC0-1", "uniprot_id": [ { "id": "A0A8C2QFC0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QFC0", "type": "external" } ], "mass": 21895.0, "length": 219, "protein_name": "Histone H1.4 isoform X2", "gene_name": "LOC100761846", "organism": "Hamster", "refseq_name": "histone H1.4 isoform X2", "refseq_ac": [ { "id": "XP_027265301", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265301", "type": "external" } ], "gene_names_uniprotkb": "LOC100761846", "gene_names_refseq": "LOC100761846", "protein_names_uniprotkb": "Histone H1.4 isoform X2", "protein_names_refseq": "histone H1.4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100761846)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042826 histone deacetylase binding;GO:0031490 chromatin DNA binding;GO:0030527 structural constituent of chromatin", "go_cellular_component": "GO:0016607 nuclear speck;GO:0000792 heterochromatin;GO:0000786 nucleosome", "go_biological_process": "GO:0006334 nucleosome assembly;GO:0030261 chromosome condensation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QFC0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QFD3-1", "uniprot_id": [ { "id": "A0A8C2QFD3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QFD3", "type": "external" } ], "mass": 17480.0, "length": 150, "protein_name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial", "gene_name": "LOC100770782", "organism": "Hamster", "refseq_name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial-like", "refseq_ac": [ { "id": "XP_035296676", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035296676", "type": "external" } ], "gene_names_uniprotkb": "LOC100770782", "gene_names_refseq": "LOC100770782", "protein_names_uniprotkb": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial; Complex I-ESSS; NADH-ubiquinone oxidoreductase ESSS subunit", "protein_names_refseq": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100770782)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0022904 respiratory electron transport chain", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QFD3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QFE6-1", "uniprot_id": [ { "id": "A0A8C2QFE6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QFE6", "type": "external" } ], "mass": 9060.0, "length": 83, "protein_name": "40S ribosomal protein S21", "gene_name": "LOC100772789", "organism": "Hamster", "refseq_name": "40S ribosomal protein S21-like", "refseq_ac": [ { "id": "XP_035293430", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293430", "type": "external" } ], "gene_names_uniprotkb": "LOC100772789", "gene_names_refseq": "LOC100772789", "protein_names_uniprotkb": "40S ribosomal protein S21", "protein_names_refseq": "40S ribosomal protein S21-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100772789)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616171.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005791 rough endoplasmic reticulum;GO:0022626 cytosolic ribosome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QFE6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QFG4-1", "uniprot_id": [ { "id": "A0A8C2QFG4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QFG4", "type": "external" } ], "mass": 35350.0, "length": 319, "protein_name": "Olfactory receptor", "gene_name": "LOC100750745", "organism": "Hamster", "refseq_name": "olfactory receptor 1444", "refseq_ac": [ { "id": "XP_003514537", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514537", "type": "external" } ], "gene_names_uniprotkb": "LOC100750745", "gene_names_refseq": "LOC100750745", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1444", "tax_id": 10029, "disease": "", "pathway": " (cge:100750745)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616654.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003514537.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QFG4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QFH8-1", "uniprot_id": [ { "id": "A0A8C2QFH8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QFH8", "type": "external" } ], "mass": 62040.0, "length": 560, "protein_name": "Protein downstream neighbor of Son isoform X2", "gene_name": "Donson", "organism": "Hamster", "refseq_name": "protein downstream neighbor of Son isoform X2", "refseq_ac": [ { "id": "XP_027271399", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271399", "type": "external" } ], "gene_names_uniprotkb": "Donson", "gene_names_refseq": "Donson", "protein_names_uniprotkb": "Protein downstream neighbor of Son isoform X2", "protein_names_refseq": "protein downstream neighbor of Son isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100769724)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0030894 replisome;GO:0005634 nucleus", "go_biological_process": "GO:0007095 mitotic G2 DNA damage checkpoint signaling;GO:0033260 nuclear DNA replication;GO:0031297 replication fork processing;GO:0033314 mitotic DNA replication checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QFH8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QFJ2-1", "uniprot_id": [ { "id": "A0A8C2QFJ2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QFJ2", "type": "external" } ], "mass": 40638.0, "length": 370, "protein_name": "Phosphoserine aminotransferase", "gene_name": "Psat1", "organism": "Hamster", "refseq_name": "phosphoserine aminotransferase isoform X1", "refseq_ac": [ { "id": "XP_007653188", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653188", "type": "external" } ], "gene_names_uniprotkb": "Psat1", "gene_names_refseq": "Psat1", "protein_names_uniprotkb": "Phosphoserine aminotransferase; 2.6.1.52", "protein_names_refseq": "phosphoserine aminotransferase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100760751)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 131 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003617202.1) and transcript sequence (JP039257.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in L-serine biosynthesis via the phosphorylated pathway, a three-step pathway converting the glycolytic intermediate 3-phospho-D-glycerate into L-serine. Catalyzes the second step, that is the pyridoxal 5'-phosphate-dependent transamination of 3-phosphohydroxypyruvate and L-glutamate to O-phosphoserine (OPS) and alpha-ketoglutarate. Acts as an inhibitor of ferroptosis in response to interferon-gamma (IFNG) by promoting GPX4 stability: following phosphorylation by CAMK2A, PSAT1 interacts with GPX4 and provides 2-oxoglutarate to EGLN3, leading to GPX4 hydroxylation and stability., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.6.1.52", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.52", "type": "external" } ], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0004648 O-phospho-L-serine:2-oxoglutarate aminotransferase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006564 L-serine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QFJ2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QFJ9-1", "uniprot_id": [ { "id": "A0A8C2QFJ9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QFJ9", "type": "external" } ], "mass": 50512.0, "length": 453, "protein_name": "Serine incorporator 1", "gene_name": "Serinc1", "organism": "Hamster", "refseq_name": "serine incorporator 1 isoform X1", "refseq_ac": [ { "id": "XP_007642935", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642935", "type": "external" } ], "gene_names_uniprotkb": "Serinc1", "gene_names_refseq": "Serinc1", "protein_names_uniprotkb": "Serine incorporator 1; Tumor differentially expressed protein 2", "protein_names_refseq": "serine incorporator 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100753040)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 473 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614045.1) and transcript sequence (JP045053.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Enhances the incorporation of serine into phosphatidylserine and sphingolipids., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0008654 phospholipid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QFJ9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QFL9-1", "uniprot_id": [ { "id": "A0A8C2QFL9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QFL9", "type": "external" } ], "mass": 49757.0, "length": 435, "protein_name": "Ras association domain-containing protein 9", "gene_name": "Rassf9", "organism": "Hamster", "refseq_name": "ras association domain-containing protein 9", "refseq_ac": [ { "id": "XP_003503459", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503459", "type": "external" } ], "gene_names_uniprotkb": "Rassf9", "gene_names_refseq": "Rassf9", "protein_names_uniprotkb": "Ras association domain-containing protein 9; PAM COOH-terminal interactor protein 1; Peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor", "protein_names_refseq": "ras association domain-containing protein 9", "tax_id": 10029, "disease": "", "pathway": " (cge:100760002)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613967.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May play a role in regulating vesicuar trafficking in cells., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0012510 trans-Golgi network transport vesicle membrane;GO:0005829 cytosol;GO:0055037 recycling endosome", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QFL9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QFN2-1", "uniprot_id": [ { "id": "A0A8C2QFN2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QFN2", "type": "external" } ], "mass": 64733.0, "length": 613, "protein_name": "Transcription factor Sp2", "gene_name": "Sp2", "organism": "Hamster", "refseq_name": "transcription factor Sp2 isoform X2", "refseq_ac": [ { "id": "XP_027279992", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279992", "type": "external" } ], "gene_names_uniprotkb": "Sp2", "gene_names_refseq": "Sp2", "protein_names_uniprotkb": "Transcription factor Sp2", "protein_names_refseq": "transcription factor Sp2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762021)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042826 histone deacetylase binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005654 nucleoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QFN2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QFQ2-1", "uniprot_id": [ { "id": "A0A8C2QFQ2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QFQ2", "type": "external" } ], "mass": 85895.0, "length": 773, "protein_name": "Cytoskeleton-associated protein 2-like isoform X2", "gene_name": "Ckap2l", "organism": "Hamster", "refseq_name": "cytoskeleton-associated protein 2-like isoform X2", "refseq_ac": [ { "id": "XP_027277633", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277633", "type": "external" } ], "gene_names_uniprotkb": "Ckap2l", "gene_names_refseq": "Ckap2l", "protein_names_uniprotkb": "Cytoskeleton-associated protein 2-like isoform X2", "protein_names_refseq": "cytoskeleton-associated protein 2-like isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754478)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005813 centrosome;GO:0005829 cytosol;GO:0072686 mitotic spindle", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QFQ2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QFT4-1", "uniprot_id": [ { "id": "A0A8C2QFT4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QFT4", "type": "external" } ], "mass": 397896.0, "length": 3610, "protein_name": "Zinc finger homeobox protein 4", "gene_name": "Zfhx4", "organism": "Hamster", "refseq_name": "zinc finger homeobox protein 4 isoform X2", "refseq_ac": [ { "id": "XP_027254590", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254590", "type": "external" } ], "gene_names_uniprotkb": "Zfhx4", "gene_names_refseq": "Zfhx4", "protein_names_uniprotkb": "Zinc finger homeobox protein 4; Zinc finger homeodomain protein 4", "protein_names_refseq": "zinc finger homeobox protein 4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100764869)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May play a role in neural and muscle differentiation. May be involved in transcriptional regulation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QFT4-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QFU2-1", "uniprot_id": [ { "id": "A0A8C2QFU2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QFU2", "type": "external" } ], "mass": 21549.0, "length": 189, "protein_name": "Receptor expression-enhancing protein", "gene_name": "Reep5", "organism": "Hamster", "refseq_name": "receptor expression-enhancing protein 5 isoform X2", "refseq_ac": [ { "id": "XP_027256506", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256506", "type": "external" } ], "gene_names_uniprotkb": "Reep5", "gene_names_refseq": "Reep5", "protein_names_uniprotkb": "Receptor expression-enhancing protein", "protein_names_refseq": "receptor expression-enhancing protein 5 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100753505)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays an essential role in heart function and development by regulating the organization and function of the sarcoplasmic reticulum in cardiomyocytes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0033017 sarcoplasmic reticulum membrane;GO:0071782 endoplasmic reticulum tubular network", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QFU2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QFU9-1", "uniprot_id": [ { "id": "A0A8C2QFU9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QFU9", "type": "external" } ], "mass": 34692.0, "length": 312, "protein_name": "Olfactory receptor", "gene_name": "LOC100770256", "organism": "Hamster", "refseq_name": "olfactory receptor 4F3/4F16/4F29", "refseq_ac": [ { "id": "XP_027276800", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276800", "type": "external" } ], "gene_names_uniprotkb": "LOC100770256", "gene_names_refseq": "LOC100770256", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 4F3/4F16/4F29", "tax_id": 10029, "disease": "", "pathway": " (cge:100770256)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QFU9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QFW4-1", "uniprot_id": [ { "id": "A0A8C2QFW4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QFW4", "type": "external" } ], "mass": 9170.0, "length": 84, "protein_name": "CDC42 small effector protein 2", "gene_name": "LOC100758446", "organism": "Hamster", "refseq_name": "CDC42 small effector protein 2", "refseq_ac": [ { "id": "XP_027283285", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283285", "type": "external" } ], "gene_names_uniprotkb": "LOC100758446", "gene_names_refseq": "LOC100758446", "protein_names_uniprotkb": "CDC42 small effector protein 2", "protein_names_refseq": "CDC42 small effector protein 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100758446)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031267 small GTPase binding;GO:0035591 signaling adaptor activity", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005856 cytoskeleton", "go_biological_process": "GO:0006909 phagocytosis;GO:0035023 regulation of Rho protein signal transduction;GO:0008360 regulation of cell shape", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QFW4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QFX0-1", "uniprot_id": [ { "id": "A0A8C2QFX0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QFX0", "type": "external" } ], "mass": 56181.0, "length": 511, "protein_name": "Zinc finger CCCH-type with G patch domain-containing protein", "gene_name": "Zgpat", "organism": "Hamster", "refseq_name": "zinc finger CCCH-type with G patch domain-containing protein isoform X2", "refseq_ac": [ { "id": "XP_027275758", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275758", "type": "external" } ], "gene_names_uniprotkb": "Zgpat", "gene_names_refseq": "Zgpat", "protein_names_uniprotkb": "Zinc finger CCCH-type with G patch domain-containing protein", "protein_names_refseq": "zinc finger CCCH-type with G patch domain-containing protein isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767467)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QFX0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QFX8-1", "uniprot_id": [ { "id": "A0A8C2QFX8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QFX8", "type": "external" } ], "mass": 35424.0, "length": 314, "protein_name": "Olfactory receptor", "gene_name": "LOC100762928", "organism": "Hamster", "refseq_name": "olfactory receptor 5W2", "refseq_ac": [ { "id": "XP_003505222", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505222", "type": "external" } ], "gene_names_uniprotkb": "LOC100762928", "gene_names_refseq": "LOC100762928", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 5W2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762928)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614125.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Odorant receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QFX8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QG11-1", "uniprot_id": [ { "id": "A0A8C2QG11_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QG11", "type": "external" } ], "mass": 38203.0, "length": 341, "protein_name": "Thioredoxin-related transmembrane protein 4 isoform X2", "gene_name": "Tmx4", "organism": "Hamster", "refseq_name": "thioredoxin-related transmembrane protein 4 isoform X2", "refseq_ac": [ { "id": "XP_027277493", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277493", "type": "external" } ], "gene_names_uniprotkb": "Tmx4", "gene_names_refseq": "Tmx4", "protein_names_uniprotkb": "Thioredoxin-related transmembrane protein 4 isoform X2", "protein_names_refseq": "thioredoxin-related transmembrane protein 4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100752266)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015036 disulfide oxidoreductase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0005637 nuclear inner membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QG11-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QG25-1", "uniprot_id": [ { "id": "A0A8C2QG25_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QG25", "type": "external" } ], "mass": 42716.0, "length": 391, "protein_name": "Somatostatin receptor type 1 isoform X2", "gene_name": "Sstr1", "organism": "Hamster", "refseq_name": "somatostatin receptor type 1 isoform X2", "refseq_ac": [ { "id": "XP_035300801", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300801", "type": "external" } ], "gene_names_uniprotkb": "Sstr1", "gene_names_refseq": "Sstr1", "protein_names_uniprotkb": "Somatostatin receptor type 1 isoform X2", "protein_names_refseq": "somatostatin receptor type 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100766048)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004994 somatostatin receptor activity;GO:0042923 neuropeptide binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043005 neuron projection", "go_biological_process": "GO:0071392 cellular response to estradiol stimulus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QG25-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QG76-1", "uniprot_id": [ { "id": "A0A8C2QG76_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QG76", "type": "external" } ], "mass": 26204.0, "length": 243, "protein_name": "Collagen triple helix repeat-containing protein 1 isoform X2", "gene_name": "Cthrc1", "organism": "Hamster", "refseq_name": "collagen triple helix repeat-containing protein 1 isoform X2", "refseq_ac": [ { "id": "XP_027287163", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287163", "type": "external" } ], "gene_names_uniprotkb": "Cthrc1", "gene_names_refseq": "Cthrc1", "protein_names_uniprotkb": "Collagen triple helix repeat-containing protein 1 isoform X2", "protein_names_refseq": "collagen triple helix repeat-containing protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:103163281)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048603.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027287163.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005109 frizzled binding;GO:0017147 Wnt-protein binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QG76-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QG85-1", "uniprot_id": [ { "id": "A0A8C2QG85_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QG85", "type": "external" } ], "mass": 14994.0, "length": 130, "protein_name": "40S ribosomal protein S24", "gene_name": "LOC100763697", "organism": "Hamster", "refseq_name": "40S ribosomal protein S24-like", "refseq_ac": [ { "id": "XP_035297391", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297391", "type": "external" } ], "gene_names_uniprotkb": "LOC100763697", "gene_names_refseq": "LOC100763697", "protein_names_uniprotkb": "40S ribosomal protein S24", "protein_names_refseq": "40S ribosomal protein S24-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100763697)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QG85-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QGA5-1", "uniprot_id": [ { "id": "A0A8C2QGA5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QGA5", "type": "external" } ], "mass": 35563.0, "length": 315, "protein_name": "Olfactory receptor", "gene_name": "LOC113836114", "organism": "Hamster", "refseq_name": "olfactory receptor 6K3-like", "refseq_ac": [ { "id": "XP_027274867", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274867", "type": "external" } ], "gene_names_uniprotkb": "LOC113836114", "gene_names_refseq": "LOC113836114", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 6K3-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113836114)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027274867.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QGA5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QGB2-1", "uniprot_id": [ { "id": "A0A8C2QGB2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QGB2", "type": "external" } ], "mass": 35154.0, "length": 311, "protein_name": "Olfactory receptor", "gene_name": "LOC100760498", "organism": "Hamster", "refseq_name": "olfactory receptor 4C15-like", "refseq_ac": [ { "id": "XP_003505467", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505467", "type": "external" } ], "gene_names_uniprotkb": "LOC100760498", "gene_names_refseq": "LOC100760498", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 4C15-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100760498)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614149.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QGB2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QGB4-1", "uniprot_id": [ { "id": "A0A8C2QGB4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QGB4", "type": "external" } ], "mass": 17262.0, "length": 149, "protein_name": "ALK and LTK ligand 2 isoform X1", "gene_name": "Alkal2", "organism": "Hamster", "refseq_name": "ALK and LTK ligand 2 isoform X1", "refseq_ac": [ { "id": "XP_035304164", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304164", "type": "external" } ], "gene_names_uniprotkb": "Alkal2", "gene_names_refseq": "Alkal2", "protein_names_uniprotkb": "ALK and LTK ligand 2 isoform X1", "protein_names_refseq": "ALK and LTK ligand 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100774090)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005125 cytokine activity;GO:0030971 receptor tyrosine kinase binding;GO:0030298 receptor signaling protein tyrosine kinase activator activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0010976 positive regulation of neuron projection development;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0070378 positive regulation of ERK5 cascade", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QGB4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QGC2-1", "uniprot_id": [ { "id": "A0A8C2QGC2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QGC2", "type": "external" } ], "mass": 35778.0, "length": 319, "protein_name": "Olfactory receptor", "gene_name": "LOC100760753", "organism": "Hamster", "refseq_name": "olfactory receptor 6F1", "refseq_ac": [ { "id": "XP_003515158", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003515158", "type": "external" } ], "gene_names_uniprotkb": "LOC100760753", "gene_names_refseq": "LOC100760753", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 6F1", "tax_id": 10029, "disease": "", "pathway": " (cge:100760753)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003617363.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Possible taste receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QGC2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QGD5-1", "uniprot_id": [ { "id": "A0A8C2QGD5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QGD5", "type": "external" } ], "mass": 56395.0, "length": 497, "protein_name": "Nuclear fragile X mental retardation-interacting protein 1", "gene_name": "Nufip1", "organism": "Hamster", "refseq_name": "nuclear fragile X mental retardation-interacting protein 1", "refseq_ac": [ { "id": "XP_027245920", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245920", "type": "external" } ], "gene_names_uniprotkb": "Nufip1", "gene_names_refseq": "Nufip1", "protein_names_uniprotkb": "Nuclear fragile X mental retardation-interacting protein 1", "protein_names_refseq": "nuclear fragile X mental retardation-interacting protein 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100768910)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0030674 protein-macromolecule adaptor activity;GO:0042802 identical protein binding;GO:0051117 ATPase binding;GO:0030515 snoRNA binding", "go_cellular_component": "GO:0005726 perichromatin fibrils;GO:0005730 nucleolus;GO:0008023 transcription elongation factor complex;GO:0045202 synapse;GO:0016363 nuclear matrix", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0000492 box C/D snoRNP assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QGD5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QGD9-1", "uniprot_id": [ { "id": "A0A8C2QGD9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QGD9", "type": "external" } ], "mass": 112380.0, "length": 975, "protein_name": "Importin-11", "gene_name": "Ipo11", "organism": "Hamster", "refseq_name": "importin-11 isoform X1", "refseq_ac": [ { "id": "XP_003496260", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496260", "type": "external" } ], "gene_names_uniprotkb": "Ipo11", "gene_names_refseq": "Ipo11", "protein_names_uniprotkb": "Importin-11; Ran-binding protein 11", "protein_names_refseq": "importin-11 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100756698)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613614.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005829 cytosol", "go_biological_process": "GO:0006606 protein import into nucleus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QGD9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QGG5-1", "uniprot_id": [ { "id": "A0A8C2QGG5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QGG5", "type": "external" } ], "mass": 57704.0, "length": 517, "protein_name": "Pleckstrin homology domain-containing family A member 8", "gene_name": "Plekha8", "organism": "Hamster", "refseq_name": "pleckstrin homology domain-containing family A member 8 isoform X2", "refseq_ac": [ { "id": "XP_027285459", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285459", "type": "external" } ], "gene_names_uniprotkb": "Plekha8", "gene_names_refseq": "Plekha8", "protein_names_uniprotkb": "Pleckstrin homology domain-containing family A member 8; Phosphatidylinositol-four-phosphate adapter protein 2", "protein_names_refseq": "pleckstrin homology domain-containing family A member 8 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100759631)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cargo transport protein that is required for apical transport from the trans-Golgi network (TGN). Transports AQP2 from the trans-Golgi network (TGN) to sites of AQP2 phosphorylation. Mediates the non-vesicular transport of glucosylceramide (GlcCer) from the trans-Golgi network (TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids. Binding of both phosphatidylinositol 4-phosphate (PIP) and ARF1 are essential for the GlcCer transfer ability. Also required for primary cilium formation, possibly by being involved in the transport of raft lipids to the apical membrane, and for membrane tubulation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031267 small GTPase binding;GO:0070273 phosphatidylinositol-4-phosphate binding;GO:1902387 ceramide 1-phosphate binding;GO:1902388 ceramide 1-phosphate transfer activity;GO:0051861 glycolipid binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005802 trans-Golgi network;GO:0005769 early endosome", "go_biological_process": "GO:0001576 globoside biosynthetic process;GO:0035621 ER to Golgi ceramide transport;GO:0007032 endosome organization;GO:0001881 receptor recycling;GO:0042147 retrograde transport, endosome to Golgi", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QGG5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QGG9-1", "uniprot_id": [ { "id": "A0A8C2QGG9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QGG9", "type": "external" } ], "mass": 83960.0, "length": 748, "protein_name": "Nuclear pore complex protein Nup88 isoform X2", "gene_name": "Nup88", "organism": "Hamster", "refseq_name": "nuclear pore complex protein Nup88 isoform X2", "refseq_ac": [ { "id": "XP_027282680", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282680", "type": "external" } ], "gene_names_uniprotkb": "Nup88", "gene_names_refseq": "Nup88", "protein_names_uniprotkb": "Nuclear pore complex protein Nup88 isoform X2", "protein_names_refseq": "nuclear pore complex protein Nup88 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754367)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017056 structural constituent of nuclear pore", "go_cellular_component": "GO:0005643 nuclear pore", "go_biological_process": "GO:0000055 ribosomal large subunit export from nucleus;GO:0006406 mRNA export from nucleus;GO:0006606 protein import into nucleus;GO:0000056 ribosomal small subunit export from nucleus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QGG9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QGH1-1", "uniprot_id": [ { "id": "A0A8C2QGH1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QGH1", "type": "external" } ], "mass": 10360.0, "length": 94, "protein_name": "FXYD domain-containing ion transport regulator", "gene_name": "Fxyd6", "organism": "Hamster", "refseq_name": "FXYD domain-containing ion transport regulator 6", "refseq_ac": [ { "id": "XP_035293693", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293693", "type": "external" } ], "gene_names_uniprotkb": "Fxyd6", "gene_names_refseq": "Fxyd6", "protein_names_uniprotkb": "FXYD domain-containing ion transport regulator", "protein_names_refseq": "FXYD domain-containing ion transport regulator 6", "tax_id": 10029, "disease": "", "pathway": " (cge:100770777)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616536.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017080 sodium channel regulator activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0045211 postsynaptic membrane;GO:0042734 presynaptic membrane", "go_biological_process": "GO:0006813 potassium ion transport;GO:0006814 sodium ion transport;GO:0043269 regulation of monoatomic ion transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QGH1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QGM5-1", "uniprot_id": [ { "id": "A0A8C2QGM5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QGM5", "type": "external" } ], "mass": 88948.0, "length": 795, "protein_name": "DNA-binding protein SATB", "gene_name": "Satb1", "organism": "Hamster", "refseq_name": "DNA-binding protein SATB1 isoform X1", "refseq_ac": [ { "id": "XP_035307622", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307622", "type": "external" } ], "gene_names_uniprotkb": "Satb1", "gene_names_refseq": "Satb1", "protein_names_uniprotkb": "DNA-binding protein SATB; Special AT-rich sequence-binding protein", "protein_names_refseq": "DNA-binding protein SATB1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100773794)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0016605 PML body;GO:0031981 nuclear lumen", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QGM5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QGN8-1", "uniprot_id": [ { "id": "A0A8C2QGN8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QGN8", "type": "external" } ], "mass": 36805.0, "length": 358, "protein_name": "G-protein coupled receptor 62", "gene_name": "LOC113835519", "organism": "Hamster", "refseq_name": "G-protein coupled receptor 62", "refseq_ac": [ { "id": "XP_027270202", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270202", "type": "external" } ], "gene_names_uniprotkb": "LOC113835519", "gene_names_refseq": "LOC113835519", "protein_names_uniprotkb": "G-protein coupled receptor 62", "protein_names_refseq": "G-protein coupled receptor 62", "tax_id": 10029, "disease": "", "pathway": " (cge:113835519)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0042802 identical protein binding;GO:1990763 arrestin family protein binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex;GO:0010008 endosome membrane", "go_biological_process": "GO:0050850 positive regulation of calcium-mediated signaling;GO:0038035 ligand-independent adenylate cyclase-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QGN8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QGQ3-1", "uniprot_id": [ { "id": "A0A8C2QGQ3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QGQ3", "type": "external" } ], "mass": 21662.0, "length": 180, "protein_name": "High mobility group protein B4", "gene_name": "Hmgb4", "organism": "Hamster", "refseq_name": "high mobility group protein B4", "refseq_ac": [ { "id": "XP_003500670", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500670", "type": "external" } ], "gene_names_uniprotkb": "Hmgb4", "gene_names_refseq": "Hmgb4", "protein_names_uniprotkb": "High mobility group protein B4", "protein_names_refseq": "high mobility group protein B4", "tax_id": 10029, "disease": "", "pathway": " (cge:100773406)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613801.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QGQ3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QGQ6-1", "uniprot_id": [ { "id": "A0A8C2QGQ6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QGQ6", "type": "external" } ], "mass": 29428.0, "length": 260, "protein_name": "Carbonic anhydrase", "gene_name": "Ca3", "organism": "Hamster", "refseq_name": "carbonic anhydrase 3 isoform X2", "refseq_ac": [ { "id": "XP_027254537", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254537", "type": "external" } ], "gene_names_uniprotkb": "Ca3", "gene_names_refseq": "Ca3", "protein_names_uniprotkb": "Carbonic anhydrase; 4.2.1.1", "protein_names_refseq": "carbonic anhydrase 3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774549)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Reversible hydration of carbon dioxide., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.2.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.1", "type": "external" }, { "id": "4.2.1.69", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.69", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004089 carbonate dehydratase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QGQ6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QGQ8-1", "uniprot_id": [ { "id": "A0A8C2QGQ8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QGQ8", "type": "external" } ], "mass": 44599.0, "length": 390, "protein_name": "polynucleotide adenylyltransferase", "gene_name": "Tent5d", "organism": "Hamster", "refseq_name": "terminal nucleotidyltransferase 5D", "refseq_ac": [ { "id": "XP_007646338", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646338", "type": "external" } ], "gene_names_uniprotkb": "Tent5d", "gene_names_refseq": "Tent5d", "protein_names_uniprotkb": "polynucleotide adenylyltransferase; 2.7.7.19", "protein_names_refseq": "terminal nucleotidyltransferase 5D", "tax_id": 10029, "disease": "", "pathway": " (cge:100755293)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614404.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.19", "type": "external" }, { "id": "2.7.7.52", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.52", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:1990817 poly(A) RNA polymerase activity", "go_cellular_component": "", "go_biological_process": "GO:0048255 mRNA stabilization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QGQ8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QGR7-1", "uniprot_id": [ { "id": "A0A8C2QGR7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QGR7", "type": "external" } ], "mass": 30139.0, "length": 262, "protein_name": "Spermatid-specific manchette-related protein 1 isoform X2", "gene_name": "CUNH9orf24", "organism": "Hamster", "refseq_name": "spermatid-specific manchette-related protein 1 isoform X2", "refseq_ac": [ { "id": "XP_035294869", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294869", "type": "external" } ], "gene_names_uniprotkb": "CUNH9orf24", "gene_names_refseq": "CUNH9orf24", "protein_names_uniprotkb": "Spermatid-specific manchette-related protein 1 isoform X2", "protein_names_refseq": "spermatid-specific manchette-related protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043014 alpha-tubulin binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm;GO:0002177 manchette", "go_biological_process": "GO:0030317 flagellated sperm motility", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QGR7-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QGS1-1", "uniprot_id": [ { "id": "A0A8C2QGS1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QGS1", "type": "external" } ], "mass": 94381.0, "length": 873, "protein_name": "F-box only protein 41", "gene_name": "Fbxo41", "organism": "Hamster", "refseq_name": "F-box only protein 41 isoform X2", "refseq_ac": [ { "id": "XP_027284551", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284551", "type": "external" } ], "gene_names_uniprotkb": "Fbxo41", "gene_names_refseq": "Fbxo41", "protein_names_uniprotkb": "F-box only protein 41", "protein_names_refseq": "F-box only protein 41 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100770848)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QGS1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QGS6-1", "uniprot_id": [ { "id": "A0A8C2QGS6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QGS6", "type": "external" } ], "mass": 39444.0, "length": 351, "protein_name": "Tropomodulin-2", "gene_name": "Tmod2", "organism": "Hamster", "refseq_name": "tropomodulin-2", "refseq_ac": [ { "id": "XP_027266941", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266941", "type": "external" } ], "gene_names_uniprotkb": "Tmod2", "gene_names_refseq": "Tmod2", "protein_names_uniprotkb": "Tropomodulin-2", "protein_names_refseq": "tropomodulin-2", "tax_id": 10029, "disease": "", "pathway": " (cge:100764008)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0005523 tropomyosin binding", "go_cellular_component": "GO:0005865 striated muscle thin filament", "go_biological_process": "GO:0006936 muscle contraction;GO:0007015 actin filament organization;GO:0051694 pointed-end actin filament capping;GO:0030239 myofibril assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QGS6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QGU0-1", "uniprot_id": [ { "id": "A0A8C2QGU0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QGU0", "type": "external" } ], "mass": 80109.0, "length": 712, "protein_name": "WD repeat-containing and planar cell polarity effector protein fritz homolog isoform X1", "gene_name": "Wdpcp", "organism": "Hamster", "refseq_name": "WD repeat-containing and planar cell polarity effector protein fritz homolog isoform X1", "refseq_ac": [ { "id": "XP_007640964", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640964", "type": "external" } ], "gene_names_uniprotkb": "Wdpcp", "gene_names_refseq": "Wdpcp", "protein_names_uniprotkb": "WD repeat-containing and planar cell polarity effector protein fritz homolog isoform X1", "protein_names_refseq": "WD repeat-containing and planar cell polarity effector protein fritz homolog isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100769859)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613880.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0097541 axonemal basal plate", "go_biological_process": "GO:0007399 nervous system development;GO:0045184 establishment of protein localization;GO:0044782 cilium organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QGU0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QGU8-1", "uniprot_id": [ { "id": "A0A8C2QGU8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QGU8", "type": "external" } ], "mass": 128694.0, "length": 1171, "protein_name": "Laminin subunit beta-3", "gene_name": "Lamb3", "organism": "Hamster", "refseq_name": "laminin subunit beta-3", "refseq_ac": [ { "id": "XP_027272363", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272363", "type": "external" } ], "gene_names_uniprotkb": "Lamb3", "gene_names_refseq": "Lamb3", "protein_names_uniprotkb": "Laminin subunit beta-3", "protein_names_refseq": "laminin subunit beta-3", "tax_id": 10029, "disease": "", "pathway": " (cge:100763082)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005610 laminin-5 complex", "go_biological_process": "GO:0016477 cell migration;GO:0009887 animal organ morphogenesis;GO:0034446 substrate adhesion-dependent cell spreading;GO:0007411 axon guidance;GO:0035987 endodermal cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QGU8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QGW8-1", "uniprot_id": [ { "id": "A0A8C2QGW8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QGW8", "type": "external" } ], "mass": 21016.0, "length": 193, "protein_name": "Ganglioside GM2 activator", "gene_name": "Gm2a", "organism": "Hamster", "refseq_name": "ganglioside GM2 activator", "refseq_ac": [ { "id": "XP_027283264", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283264", "type": "external" } ], "gene_names_uniprotkb": "Gm2a", "gene_names_refseq": "Gm2a", "protein_names_uniprotkb": "Ganglioside GM2 activator", "protein_names_refseq": "ganglioside GM2 activator", "tax_id": 10029, "disease": "", "pathway": " (cge:100759507)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005319 lipid transporter activity;GO:0008047 enzyme activator activity;GO:0004563 beta-N-acetylhexosaminidase activity", "go_cellular_component": "GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "GO:0006689 ganglioside catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QGW8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QGY3-1", "uniprot_id": [ { "id": "A0A8C2QGY3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QGY3", "type": "external" } ], "mass": 42268.0, "length": 372, "protein_name": "Alpha-parvin isoform X1", "gene_name": "Parva", "organism": "Hamster", "refseq_name": "alpha-parvin isoform X1", "refseq_ac": [ { "id": "XP_027265902", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265902", "type": "external" } ], "gene_names_uniprotkb": "Parva", "gene_names_refseq": "Parva", "protein_names_uniprotkb": "Alpha-parvin isoform X1", "protein_names_refseq": "alpha-parvin isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100763027)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0004860 protein kinase inhibitor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005925 focal adhesion;GO:0015629 actin cytoskeleton;GO:0030018 Z disc", "go_biological_process": "GO:0051017 actin filament bundle assembly;GO:0034446 substrate adhesion-dependent cell spreading;GO:0060271 cilium assembly;GO:0051639 actin filament network formation;GO:0071963 establishment or maintenance of cell polarity regulating cell shape", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QGY3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QH18-1", "uniprot_id": [ { "id": "A0A8C2QH18_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QH18", "type": "external" } ], "mass": 51761.0, "length": 444, "protein_name": "UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase", "gene_name": "Gxylt2", "organism": "Hamster", "refseq_name": "glucoside xylosyltransferase 2 isoform X2", "refseq_ac": [ { "id": "XP_027284777", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284777", "type": "external" } ], "gene_names_uniprotkb": "Gxylt2", "gene_names_refseq": "Gxylt2", "protein_names_uniprotkb": "UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase; 2.4.2.42", "protein_names_refseq": "glucoside xylosyltransferase 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100758512)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.2.42", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.42", "type": "external" } ], "go_molecular_function": "GO:0140563 UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0016266 protein O-linked glycosylation via N-acetyl-galactosamine;GO:0180059 protein O-linked glycosylation via glucose", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QH18-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QH28-1", "uniprot_id": [ { "id": "A0A8C2QH28_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QH28", "type": "external" } ], "mass": 57117.0, "length": 514, "protein_name": "Pleiotropic regulator 1", "gene_name": "Plrg1", "organism": "Hamster", "refseq_name": "pleiotropic regulator 1", "refseq_ac": [ { "id": "XP_007638415", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638415", "type": "external" } ], "gene_names_uniprotkb": "Plrg1", "gene_names_refseq": "Plrg1", "protein_names_uniprotkb": "Pleiotropic regulator 1", "protein_names_refseq": "pleiotropic regulator 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100773980)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613739.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in pre-mRNA splicing as component of the spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0071013 catalytic step 2 spliceosome;GO:0071011 precatalytic spliceosome;GO:0000974 Prp19 complex", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QH28-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QH35-1", "uniprot_id": [ { "id": "A0A8C2QH35_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QH35", "type": "external" } ], "mass": 208789.0, "length": 1923, "protein_name": "Protein Shroom3 isoform X3", "gene_name": "Shroom3", "organism": "Hamster", "refseq_name": "protein Shroom3 isoform X3", "refseq_ac": [ { "id": "XP_027244235", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244235", "type": "external" } ], "gene_names_uniprotkb": "Shroom3", "gene_names_refseq": "Shroom3", "protein_names_uniprotkb": "Protein Shroom3 isoform X3", "protein_names_refseq": "protein Shroom3 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100770119)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding", "go_cellular_component": "GO:0005874 microtubule;GO:0005912 adherens junction;GO:0016324 apical plasma membrane;GO:0030864 cortical actin cytoskeleton;GO:0043296 apical junction complex", "go_biological_process": "GO:0007015 actin filament organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QH35-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QH59-1", "uniprot_id": [ { "id": "A0A8C2QH59_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QH59", "type": "external" } ], "mass": 46779.0, "length": 416, "protein_name": "Transmembrane protease serine", "gene_name": "Tmprss11b", "organism": "Hamster", "refseq_name": "transmembrane protease serine 11B", "refseq_ac": [ { "id": "XP_007649290", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649290", "type": "external" } ], "gene_names_uniprotkb": "Tmprss11b", "gene_names_refseq": "Tmprss11b", "protein_names_uniprotkb": "Transmembrane protease serine; 3.4.21.-", "protein_names_refseq": "transmembrane protease serine 11B", "tax_id": 10029, "disease": "", "pathway": " (cge:100764295)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614886.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QH59-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QH73-1", "uniprot_id": [ { "id": "A0A8C2QH73_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QH73", "type": "external" } ], "mass": 20198.0, "length": 177, "protein_name": "Coatomer subunit zeta", "gene_name": "Copz1", "organism": "Hamster", "refseq_name": "coatomer subunit zeta-1 isoform X2", "refseq_ac": [ { "id": "XP_027252578", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027252578", "type": "external" } ], "gene_names_uniprotkb": "Copz1", "gene_names_refseq": "Copz1", "protein_names_uniprotkb": "Coatomer subunit zeta", "protein_names_refseq": "coatomer subunit zeta-1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100769319)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0030126 COPI vesicle coat", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0006891 intra-Golgi vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QH73-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QH74-1", "uniprot_id": [ { "id": "A0A8C2QH74_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QH74", "type": "external" } ], "mass": 91662.0, "length": 829, "protein_name": "Conserved oligomeric Golgi complex subunit 5", "gene_name": "Cog5", "organism": "Hamster", "refseq_name": "conserved oligomeric Golgi complex subunit 5 isoform X2", "refseq_ac": [ { "id": "XP_007649851", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649851", "type": "external" } ], "gene_names_uniprotkb": "Cog5", "gene_names_refseq": "Cog5", "protein_names_uniprotkb": "Conserved oligomeric Golgi complex subunit 5", "protein_names_refseq": "conserved oligomeric Golgi complex subunit 5 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754837)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 1106 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615032.1) and transcript sequences (IACG01087731.1 and JI865511.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007649851.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0017119 Golgi transport complex", "go_biological_process": "GO:0007030 Golgi organization;GO:0000301 retrograde transport, vesicle recycling within Golgi", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QH74-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QH78-1", "uniprot_id": [ { "id": "A0A8C2QH78_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QH78", "type": "external" } ], "mass": 66956.0, "length": 591, "protein_name": "Meiotic recombination protein REC8 homolog", "gene_name": "Rec8", "organism": "Hamster", "refseq_name": "meiotic recombination protein REC8 homolog", "refseq_ac": [ { "id": "XP_035309351", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309351", "type": "external" } ], "gene_names_uniprotkb": "Rec8", "gene_names_refseq": "Rec8", "protein_names_uniprotkb": "Meiotic recombination protein REC8 homolog", "protein_names_refseq": "meiotic recombination protein REC8 homolog", "tax_id": 10029, "disease": "", "pathway": " (cge:100770434)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding", "go_cellular_component": "GO:0030893 meiotic cohesin complex;GO:0001673 male germ cell nucleus;GO:0000776 kinetochore;GO:0000800 lateral element", "go_biological_process": "GO:0007059 chromosome segregation;GO:0006302 double-strand break repair;GO:0051177 meiotic sister chromatid cohesion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QH78-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QHB7-1", "uniprot_id": [ { "id": "A0A8C2QHB7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QHB7", "type": "external" } ], "mass": 38252.0, "length": 335, "protein_name": "H-2 class I histocompatibility antigen, Q10 alpha chain", "gene_name": "LOC100759246", "organism": "Hamster", "refseq_name": "H-2 class I histocompatibility antigen, Q10 alpha chain", "refseq_ac": [ { "id": "XP_027244425", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244425", "type": "external" } ], "gene_names_uniprotkb": "LOC100759246", "gene_names_refseq": "LOC100759246", "protein_names_uniprotkb": "H-2 class I histocompatibility antigen, Q10 alpha chain", "protein_names_refseq": "H-2 class I histocompatibility antigen, Q10 alpha chain", "tax_id": 10029, "disease": "", "pathway": " (cge:100759246)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in the presentation of foreign antigens to the immune system., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0042605 peptide antigen binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0009897 external side of plasma membrane;GO:0030670 phagocytic vesicle membrane;GO:0042612 MHC class I protein complex;GO:0098553 lumenal side of endoplasmic reticulum membrane", "go_biological_process": "GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib;GO:0006955 immune response;GO:0002486 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent;GO:0001916 positive regulation of T cell mediated cytotoxicity", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QHB7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QHG2-1", "uniprot_id": [ { "id": "A0A8C2QHG2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QHG2", "type": "external" } ], "mass": 72270.0, "length": 639, "protein_name": "Sec1 family domain-containing protein 1", "gene_name": "Scfd1", "organism": "Hamster", "refseq_name": "sec1 family domain-containing protein 1 isoform X1", "refseq_ac": [ { "id": "XP_003499221", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499221", "type": "external" } ], "gene_names_uniprotkb": "Scfd1", "gene_names_refseq": "Scfd1", "protein_names_uniprotkb": "Sec1 family domain-containing protein 1; Syntaxin-binding protein 1-like 2", "protein_names_refseq": "sec1 family domain-containing protein 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100763574)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613718.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0032580 Golgi cisterna membrane;GO:0005801 cis-Golgi network", "go_biological_process": "GO:1902902 negative regulation of autophagosome assembly;GO:0051223 regulation of protein transport;GO:0015031 protein transport;GO:0009636 response to toxic substance;GO:0016192 vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QHG2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QHH2-1", "uniprot_id": [ { "id": "A0A8C2QHH2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QHH2", "type": "external" } ], "mass": 31639.0, "length": 280, "protein_name": "Transcription factor E2F6 isoform X3", "gene_name": "E2f6", "organism": "Hamster", "refseq_name": "transcription factor E2F6 isoform X3", "refseq_ac": [ { "id": "XP_027280467", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280467", "type": "external" } ], "gene_names_uniprotkb": "E2f6", "gene_names_refseq": "E2f6", "protein_names_uniprotkb": "Transcription factor E2F6 isoform X3", "protein_names_refseq": "transcription factor E2F6 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100767557)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0071339 MLL1 complex;GO:0090575 RNA polymerase II transcription regulator complex", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QHH2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QHH3-1", "uniprot_id": [ { "id": "A0A8C2QHH3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QHH3", "type": "external" } ], "mass": 54147.0, "length": 484, "protein_name": "Threonine synthase-like 2", "gene_name": "Thnsl2", "organism": "Hamster", "refseq_name": "threonine synthase-like 2", "refseq_ac": [ { "id": "XP_035304296", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304296", "type": "external" } ], "gene_names_uniprotkb": "Thnsl2", "gene_names_refseq": "Thnsl2", "protein_names_uniprotkb": "Threonine synthase-like 2", "protein_names_refseq": "threonine synthase-like 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100768824)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0016829 lyase activity;GO:0016791 phosphatase activity;GO:0070905 serine binding", "go_cellular_component": "", "go_biological_process": "GO:0046360 2-oxobutyrate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QHH3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QHJ4-1", "uniprot_id": [ { "id": "A0A8C2QHJ4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QHJ4", "type": "external" } ], "mass": 86906.0, "length": 783, "protein_name": "Adhesion G-protein coupled receptor G7", "gene_name": "Adgrg7", "organism": "Hamster", "refseq_name": "adhesion G-protein coupled receptor G7", "refseq_ac": [ { "id": "XP_007643565", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643565", "type": "external" } ], "gene_names_uniprotkb": "Adgrg7", "gene_names_refseq": "Adgrg7", "protein_names_uniprotkb": "Adhesion G-protein coupled receptor G7; G-protein coupled receptor 128", "protein_names_refseq": "adhesion G-protein coupled receptor G7", "tax_id": 10029, "disease": "", "pathway": " (cge:100759621)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614098.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007643565.2. COMPLETENESS: full length., [RefSeq]; Orphan receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QHJ4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QHL8-1", "uniprot_id": [ { "id": "A0A8C2QHL8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QHL8", "type": "external" } ], "mass": 9633.0, "length": 84, "protein_name": "40S ribosomal protein S27-like", "gene_name": "LOC100756750", "organism": "Hamster", "refseq_name": "40S ribosomal protein S27-like", "refseq_ac": [ { "id": "XP_027282462", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282462", "type": "external" } ], "gene_names_uniprotkb": "LOC100756750", "gene_names_refseq": "LOC100756750", "protein_names_uniprotkb": "40S ribosomal protein S27-like", "protein_names_refseq": "40S ribosomal protein S27-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100756750)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005829 cytosol;GO:0005840 ribosome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QHL8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QHM8-1", "uniprot_id": [ { "id": "A0A8C2QHM8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QHM8", "type": "external" } ], "mass": 34281.0, "length": 300, "protein_name": "Taste receptor type 2", "gene_name": "LOC100771519", "organism": "Hamster", "refseq_name": "taste receptor type 2 member 104-like", "refseq_ac": [ { "id": "XP_003510595", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510595", "type": "external" } ], "gene_names_uniprotkb": "LOC100771519", "gene_names_refseq": "LOC100771519", "protein_names_uniprotkb": "Taste receptor type 2", "protein_names_refseq": "taste receptor type 2 member 104-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100771519)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614903.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0033038 bitter taste receptor activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QHM8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QHQ7-1", "uniprot_id": [ { "id": "A0A8C2QHQ7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QHQ7", "type": "external" } ], "mass": 61599.0, "length": 541, "protein_name": "Nuclear receptor subfamily 5 group A member 2 isoform X2", "gene_name": "Nr5a2", "organism": "Hamster", "refseq_name": "nuclear receptor subfamily 5 group A member 2 isoform X2", "refseq_ac": [ { "id": "XP_027273270", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273270", "type": "external" } ], "gene_names_uniprotkb": "Nr5a2", "gene_names_refseq": "Nr5a2", "protein_names_uniprotkb": "Nuclear receptor subfamily 5 group A member 2 isoform X2", "protein_names_refseq": "nuclear receptor subfamily 5 group A member 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100766752)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0008289 lipid binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0004879 nuclear receptor activity", "go_cellular_component": "GO:0090575 RNA polymerase II transcription regulator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0009755 hormone-mediated signaling pathway;GO:0009888 tissue development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QHQ7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QHR8-1", "uniprot_id": [ { "id": "A0A8C2QHR8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QHR8", "type": "external" } ], "mass": 35361.0, "length": 311, "protein_name": "Olfactory receptor", "gene_name": "LOC100753673", "organism": "Hamster", "refseq_name": "olfactory receptor 11G2", "refseq_ac": [ { "id": "XP_027242274", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027242274", "type": "external" } ], "gene_names_uniprotkb": "LOC100753673", "gene_names_refseq": "LOC100753673", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 11G2", "tax_id": 10029, "disease": "", "pathway": " (cge:100753673)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QHR8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QHT8-1", "uniprot_id": [ { "id": "A0A8C2QHT8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QHT8", "type": "external" } ], "mass": 63530.0, "length": 571, "protein_name": "Zinc finger protein 398 isoform X2", "gene_name": "LOC100763819", "organism": "Hamster", "refseq_name": "zinc finger protein 398 isoform X2", "refseq_ac": [ { "id": "XP_003512156", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512156", "type": "external" } ], "gene_names_uniprotkb": "LOC100763819", "gene_names_refseq": "LOC100763819", "protein_names_uniprotkb": "Zinc finger protein 398 isoform X2", "protein_names_refseq": "zinc finger protein 398 isoform X2", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615359.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QHT8-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QHW9-1", "uniprot_id": [ { "id": "A0A8C2QHW9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QHW9", "type": "external" } ], "mass": 101722.0, "length": 919, "protein_name": "Sarcosine dehydrogenase, mitochondrial", "gene_name": "Sardh", "organism": "Hamster", "refseq_name": "sarcosine dehydrogenase, mitochondrial isoform X1", "refseq_ac": [ { "id": "XP_003513711", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513711", "type": "external" } ], "gene_names_uniprotkb": "Sardh", "gene_names_refseq": "Sardh", "protein_names_uniprotkb": "Sarcosine dehydrogenase, mitochondrial; 1.5.8.3", "protein_names_refseq": "sarcosine dehydrogenase, mitochondrial isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100761121)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 1140 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616067.1) and transcript sequence (IACG01046747.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003513711.2. COMPLETENESS: full length., [RefSeq]; Catalyzes the last step of the oxidative degradation of choline to glycine. Converts sarcosine into glycine., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.5.8.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.8.3", "type": "external" } ], "go_molecular_function": "GO:0008480 sarcosine dehydrogenase activity", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QHW9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QI19-1", "uniprot_id": [ { "id": "A0A8C2QI19_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QI19", "type": "external" } ], "mass": 41360.0, "length": 363, "protein_name": "Transcription elongation factor, mitochondrial", "gene_name": "Tefm", "organism": "Hamster", "refseq_name": "transcription elongation factor, mitochondrial isoform X2", "refseq_ac": [ { "id": "XP_027282326", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282326", "type": "external" } ], "gene_names_uniprotkb": "Tefm", "gene_names_refseq": "Tefm", "protein_names_uniprotkb": "Transcription elongation factor, mitochondrial", "protein_names_refseq": "transcription elongation factor, mitochondrial isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100771926)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Transcription elongation factor which increases mitochondrial RNA polymerase processivity. Regulates transcription of the mitochondrial genome, including genes important for the oxidative phosphorylation machinery., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030337 DNA polymerase processivity factor activity;GO:0003676 nucleic acid binding;GO:0003746 translation elongation factor activity;GO:0003711 transcription elongation factor activity", "go_cellular_component": "GO:0042645 mitochondrial nucleoid;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006392 transcription elongation by mitochondrial RNA polymerase;GO:0002082 regulation of oxidative phosphorylation;GO:1903109 positive regulation of mitochondrial transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QI19-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QI70-1", "uniprot_id": [ { "id": "A0A8C2QI70_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QI70", "type": "external" } ], "mass": 36223.0, "length": 323, "protein_name": "Olfactory receptor", "gene_name": "LOC100752163", "organism": "Hamster", "refseq_name": "olfactory receptor 11G2", "refseq_ac": [ { "id": "XP_027242287", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027242287", "type": "external" } ], "gene_names_uniprotkb": "LOC100752163", "gene_names_refseq": "LOC100752163", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 11G2", "tax_id": 10029, "disease": "", "pathway": " (cge:100752163)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QI70-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QI79-1", "uniprot_id": [ { "id": "A0A8C2QI79_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QI79", "type": "external" } ], "mass": 43275.0, "length": 370, "protein_name": "Translocating chain-associated membrane protein", "gene_name": "Tram2", "organism": "Hamster", "refseq_name": "translocating chain-associated membrane protein 2", "refseq_ac": [ { "id": "XP_003509171", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509171", "type": "external" } ], "gene_names_uniprotkb": "Tram2", "gene_names_refseq": "Tram2", "protein_names_uniprotkb": "Translocating chain-associated membrane protein", "protein_names_refseq": "translocating chain-associated membrane protein 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100773824)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614654.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0045048 protein insertion into ER membrane;GO:0032964 collagen biosynthetic process;GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QI79-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QI82-1", "uniprot_id": [ { "id": "A0A8C2QI82_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QI82", "type": "external" } ], "mass": 27211.0, "length": 246, "protein_name": "Protein YIPF", "gene_name": "Yipf4", "organism": "Hamster", "refseq_name": "protein YIPF4 isoform X2", "refseq_ac": [ { "id": "XP_027281882", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281882", "type": "external" } ], "gene_names_uniprotkb": "Yipf4", "gene_names_refseq": "Yipf4", "protein_names_uniprotkb": "Protein YIPF", "protein_names_refseq": "protein YIPF4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100765339)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in the maintenance of the Golgi structure., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0048280 vesicle fusion with Golgi apparatus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QI82-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QI83-1", "uniprot_id": [ { "id": "A0A8C2QI83_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QI83", "type": "external" } ], "mass": 66784.0, "length": 592, "protein_name": "Inactive heparanase-2 isoform X1", "gene_name": "Hpse2", "organism": "Hamster", "refseq_name": "inactive heparanase-2 isoform X1", "refseq_ac": [ { "id": "XP_035298958", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298958", "type": "external" } ], "gene_names_uniprotkb": "Hpse2", "gene_names_refseq": "Hpse2", "protein_names_uniprotkb": "Inactive heparanase-2 isoform X1", "protein_names_refseq": "inactive heparanase-2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100762007)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043395 heparan sulfate proteoglycan binding;GO:0016798 hydrolase activity, acting on glycosyl bonds", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane;GO:0031012 extracellular matrix", "go_biological_process": "GO:0030198 extracellular matrix organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QI83-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QIB6-1", "uniprot_id": [ { "id": "A0A8C2QIB6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QIB6", "type": "external" } ], "mass": 106996.0, "length": 967, "protein_name": "Zinc finger protein 280D isoform X1", "gene_name": "Znf280d", "organism": "Hamster", "refseq_name": "zinc finger protein 280D isoform X1", "refseq_ac": [ { "id": "XP_007645785", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645785", "type": "external" } ], "gene_names_uniprotkb": "Znf280d", "gene_names_refseq": "Znf280d", "protein_names_uniprotkb": "Zinc finger protein 280D isoform X1", "protein_names_refseq": "zinc finger protein 280D isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100770583)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613582.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May function as a transcription factor., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QIB6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QIC2-1", "uniprot_id": [ { "id": "A0A8C2QIC2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QIC2", "type": "external" } ], "mass": 24712.0, "length": 214, "protein_name": "Phosphatidylcholine transfer protein", "gene_name": "Pctp", "organism": "Hamster", "refseq_name": "phosphatidylcholine transfer protein isoform X2", "refseq_ac": [ { "id": "XP_027282078", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282078", "type": "external" } ], "gene_names_uniprotkb": "Pctp", "gene_names_refseq": "Pctp", "protein_names_uniprotkb": "Phosphatidylcholine transfer protein; START domain-containing protein 2; StAR-related lipid transfer protein 2", "protein_names_refseq": "phosphatidylcholine transfer protein isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763937)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031210 phosphatidylcholine binding;GO:0008525 phosphatidylcholine transporter activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QIC2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QID5-1", "uniprot_id": [ { "id": "A0A8C2QID5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QID5", "type": "external" } ], "mass": 97317.0, "length": 861, "protein_name": "E3 ubiquitin-protein ligase HECTD3", "gene_name": "Hectd3", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase HECTD3 isoform X2", "refseq_ac": [ { "id": "XP_027258387", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258387", "type": "external" } ], "gene_names_uniprotkb": "Hectd3", "gene_names_refseq": "Hectd3", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase HECTD3; 2.3.2.26; HECT domain-containing protein 3; HECT-type E3 ubiquitin transferase HECTD3", "protein_names_refseq": "E3 ubiquitin-protein ligase HECTD3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762194)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019905 syntaxin binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QID5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QIE4-1", "uniprot_id": [ { "id": "A0A8C2QIE4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QIE4", "type": "external" } ], "mass": 57439.0, "length": 524, "protein_name": "Keratin, type II cytoskeletal 71 isoform X2", "gene_name": "LOC100754630", "organism": "Hamster", "refseq_name": "keratin, type II cytoskeletal 71 isoform X2", "refseq_ac": [ { "id": "XP_027251836", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251836", "type": "external" } ], "gene_names_uniprotkb": "LOC100754630", "gene_names_refseq": "LOC100754630", "protein_names_uniprotkb": "Keratin, type II cytoskeletal 71 isoform X2", "protein_names_refseq": "keratin, type II cytoskeletal 71 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754630)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030280 structural constituent of skin epidermis", "go_cellular_component": "GO:0005615 extracellular space;GO:0045095 keratin filament", "go_biological_process": "GO:0031424 keratinization;GO:0045109 intermediate filament organization;GO:0031069 hair follicle morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QIE4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QIL8-1", "uniprot_id": [ { "id": "A0A8C2QIL8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QIL8", "type": "external" } ], "mass": 37678.0, "length": 364, "protein_name": "Homeobox protein Nkx-6.1 isoform X2", "gene_name": "LOC100772326", "organism": "Hamster", "refseq_name": "homeobox protein Nkx-6.1 isoform X2", "refseq_ac": [ { "id": "XP_027244327", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244327", "type": "external" } ], "gene_names_uniprotkb": "LOC100772326", "gene_names_refseq": "LOC100772326", "protein_names_uniprotkb": "Homeobox protein Nkx-6.1 isoform X2", "protein_names_refseq": "homeobox protein Nkx-6.1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772326)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0035883 enteroendocrine cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QIL8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QIN3-1", "uniprot_id": [ { "id": "A0A8C2QIN3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QIN3", "type": "external" } ], "mass": 29040.0, "length": 251, "protein_name": "Cyclin-Q", "gene_name": "Ccnq", "organism": "Hamster", "refseq_name": "cyclin-Q isoform X2", "refseq_ac": [ { "id": "XP_027281931", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281931", "type": "external" } ], "gene_names_uniprotkb": "Ccnq", "gene_names_refseq": "Ccnq", "protein_names_uniprotkb": "Cyclin-Q; CDK10-activating cyclin; Cyclin-M; Cyclin-related protein FAM58A", "protein_names_refseq": "cyclin-Q isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100769050)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Activating cyclin for the cyclin-associated kinase CDK10., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030295 protein kinase activator activity;GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity", "go_cellular_component": "", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QIN3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QIP5-1", "uniprot_id": [ { "id": "A0A8C2QIP5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QIP5", "type": "external" } ], "mass": 29931.0, "length": 269, "protein_name": "Ciliary microtubule inner protein 2B", "gene_name": "Fam166b", "organism": "Hamster", "refseq_name": "protein FAM166B", "refseq_ac": [ { "id": "XP_003505060", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505060", "type": "external" } ], "gene_names_uniprotkb": "Fam166b", "gene_names_refseq": "Fam166b", "protein_names_uniprotkb": "Ciliary microtubule inner protein 2B", "protein_names_refseq": "protein FAM166B", "tax_id": 10029, "disease": "", "pathway": " (cge:100757125)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614108.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005879 axonemal microtubule", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QIP5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QIQ2-1", "uniprot_id": [ { "id": "A0A8C2QIQ2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QIQ2", "type": "external" } ], "mass": 27135.0, "length": 243, "protein_name": "Intestine-specific homeobox", "gene_name": "Isx", "organism": "Hamster", "refseq_name": "intestine-specific homeobox", "refseq_ac": [ { "id": "XP_016819311", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016819311", "type": "external" } ], "gene_names_uniprotkb": "Isx", "gene_names_refseq": "Isx", "protein_names_uniprotkb": "Intestine-specific homeobox", "protein_names_refseq": "intestine-specific homeobox", "tax_id": 10029, "disease": "", "pathway": " (cge:100756409)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003617336.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Transcription factor that regulates gene expression in intestine. May participate in vitamin A metabolism most likely by regulating BCO1 expression in the intestine., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QIQ2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QIR9-1", "uniprot_id": [ { "id": "A0A8C2QIR9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QIR9", "type": "external" } ], "mass": 22500.0, "length": 196, "protein_name": "Beta-crystallin A4", "gene_name": "Cryba4", "organism": "Hamster", "refseq_name": "beta-crystallin A4", "refseq_ac": [ { "id": "XP_027271743", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271743", "type": "external" } ], "gene_names_uniprotkb": "Cryba4", "gene_names_refseq": "Cryba4", "protein_names_uniprotkb": "Beta-crystallin A4; Beta-A4 crystallin", "protein_names_refseq": "beta-crystallin A4", "tax_id": 10029, "disease": "", "pathway": " (cge:100772464)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027271743.1. COMPLETENESS: full length., [RefSeq]; Crystallins are the dominant structural components of the vertebrate eye lens., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0005212 structural constituent of eye lens", "go_cellular_component": "", "go_biological_process": "GO:0007601 visual perception;GO:0002088 lens development in camera-type eye", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QIR9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QIS6-1", "uniprot_id": [ { "id": "A0A8C2QIS6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QIS6", "type": "external" } ], "mass": 11667.0, "length": 103, "protein_name": "C-C motif chemokine", "gene_name": "Ccl17", "organism": "Hamster", "refseq_name": "C-C motif chemokine 17", "refseq_ac": [ { "id": "XP_007642403", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642403", "type": "external" } ], "gene_names_uniprotkb": "Ccl17", "gene_names_refseq": "Ccl17", "protein_names_uniprotkb": "C-C motif chemokine", "protein_names_refseq": "C-C motif chemokine 17", "tax_id": 10029, "disease": "", "pathway": " (cge:100764062)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613984.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes. Acts by binding to CCR4 at T-cell surface. Mediates GM-CSF/CSF2-driven pain and inflammation. In the brain, required to maintain the typical, highly branched morphology of hippocampal microglia under homeostatic conditions. May be important for the appropriate adaptation of microglial morphology and synaptic plasticity to acute lipopolysaccharide (LPS)-induced neuroinflammation. Plays a role in wound healing, mainly by inducing fibroblast migration into the wound., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008009 chemokine activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006954 inflammatory response;GO:0006955 immune response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QIS6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QIT0-1", "uniprot_id": [ { "id": "A0A8C2QIT0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QIT0", "type": "external" } ], "mass": 197481.0, "length": 1749, "protein_name": "Intraflagellar transport protein 172 homolog", "gene_name": "Ift172", "organism": "Hamster", "refseq_name": "intraflagellar transport protein 172 homolog", "refseq_ac": [ { "id": "XP_003496627", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496627", "type": "external" } ], "gene_names_uniprotkb": "Ift172", "gene_names_refseq": "Ift172", "protein_names_uniprotkb": "Intraflagellar transport protein 172 homolog", "protein_names_refseq": "intraflagellar transport protein 172 homolog", "tax_id": 10029, "disease": "", "pathway": " (cge:100757945)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613628.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Required for the maintenance and formation of cilia. Plays an indirect role in hedgehog (Hh) signaling, cilia being required for all activity of the hedgehog pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005930 axoneme;GO:0036064 ciliary basal body;GO:0030992 intraciliary transport particle B", "go_biological_process": "GO:0042073 intraciliary transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QIT0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QIT6-1", "uniprot_id": [ { "id": "A0A8C2QIT6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QIT6", "type": "external" } ], "mass": 41999.0, "length": 363, "protein_name": "ethanolamine kinase", "gene_name": "Etnk1", "organism": "Hamster", "refseq_name": "ethanolamine kinase 1 isoform X3", "refseq_ac": [ { "id": "XP_027285957", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285957", "type": "external" } ], "gene_names_uniprotkb": "Etnk1", "gene_names_refseq": "Etnk1", "protein_names_uniprotkb": "ethanolamine kinase; 2.7.1.82", "protein_names_refseq": "ethanolamine kinase 1 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100765795)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0004305 ethanolamine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006646 phosphatidylethanolamine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QIT6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QIW1-1", "uniprot_id": [ { "id": "A0A8C2QIW1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QIW1", "type": "external" } ], "mass": 30443.0, "length": 282, "protein_name": "Fibroblast growth factor-binding protein 3-like", "gene_name": "LOC103159471", "organism": "Hamster", "refseq_name": "fibroblast growth factor-binding protein 3-like", "refseq_ac": [ { "id": "XP_027262134", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262134", "type": "external" } ], "gene_names_uniprotkb": "LOC103159471", "gene_names_refseq": "LOC103159471", "protein_names_uniprotkb": "Fibroblast growth factor-binding protein 3-like", "protein_names_refseq": "fibroblast growth factor-binding protein 3-like", "tax_id": 10029, "disease": "", "pathway": " (cge:103159471)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008201 heparin binding;GO:0017134 fibroblast growth factor binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0007267 cell-cell signaling", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QIW1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QIX1-1", "uniprot_id": [ { "id": "A0A8C2QIX1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QIX1", "type": "external" } ], "mass": 116662.0, "length": 1048, "protein_name": "Malignant fibrous histiocytoma-amplified sequence 1 isoform X3", "gene_name": "Mfhas1", "organism": "Hamster", "refseq_name": "malignant fibrous histiocytoma-amplified sequence 1 isoform X3", "refseq_ac": [ { "id": "XP_027247049", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247049", "type": "external" } ], "gene_names_uniprotkb": "Mfhas1", "gene_names_refseq": "Mfhas1", "protein_names_uniprotkb": "Malignant fibrous histiocytoma-amplified sequence 1 isoform X3", "protein_names_refseq": "malignant fibrous histiocytoma-amplified sequence 1 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100773872)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Probable GTP-binding protein. Functions in innate immunity and more specifically the inflammatory response as a regulator of the Toll-like receptor TLR2 and TLR4 signaling pathways. Negatively regulates the part of the TLR4 signaling pathway that leads to the activation of the transcription factor AP-1. By retaining the phosphatase complex PP2A into the cytoplasm, prevents the dephosphorylation of the AP-1 subunit JUN which is required for proper activation of the transcription factor. Both inhibits and activates the TLR2-dependent signaling pathway. Positively regulates the TLR2 signaling pathway to activate specifically the downstream p38 and JNK MAP kinases and promote the polarization of macrophages toward the pro-inflammatory M1 phenotype. It may also play a role in the regulation of inflammation induced by high glucose through the PKB/AKT signaling pathway. Also involved in erythrocyte differentiation through activation of the ERK1/ERK2 signaling pathway., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005525 GTP binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0034136 negative regulation of toll-like receptor 2 signaling pathway;GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:0034137 positive regulation of toll-like receptor 2 signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QIX1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QIX5-1", "uniprot_id": [ { "id": "A0A8C2QIX5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QIX5", "type": "external" } ], "mass": 28524.0, "length": 248, "protein_name": "Tropomyosin alpha-4 chain isoform X5", "gene_name": "Tpm4", "organism": "Hamster", "refseq_name": "tropomyosin alpha-4 chain isoform X5", "refseq_ac": [ { "id": "XP_027250711", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250711", "type": "external" } ], "gene_names_uniprotkb": "Tpm4", "gene_names_refseq": "Tpm4", "protein_names_uniprotkb": "Tropomyosin alpha-4 chain isoform X5", "protein_names_refseq": "tropomyosin alpha-4 chain isoform X5", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding", "go_cellular_component": "GO:0002102 podosome;GO:0001725 stress fiber;GO:0030863 cortical cytoskeleton", "go_biological_process": "GO:0030220 platelet formation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QIX5-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QIX7-1", "uniprot_id": [ { "id": "A0A8C2QIX7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QIX7", "type": "external" } ], "mass": 323760.0, "length": 2880, "protein_name": "Chromodomain-helicase-DNA-binding protein 9 isoform X1", "gene_name": "Chd9", "organism": "Hamster", "refseq_name": "chromodomain-helicase-DNA-binding protein 9 isoform X1", "refseq_ac": [ { "id": "XP_007619187", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007619187", "type": "external" } ], "gene_names_uniprotkb": "Chd9", "gene_names_refseq": "Chd9", "protein_names_uniprotkb": "Chromodomain-helicase-DNA-binding protein 9 isoform X1", "protein_names_refseq": "chromodomain-helicase-DNA-binding protein 9 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100769940)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613676.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QIX7-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJ10-1", "uniprot_id": [ { "id": "A0A8C2QJ10_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJ10", "type": "external" } ], "mass": 34930.0, "length": 312, "protein_name": "Olfactory receptor", "gene_name": "LOC100767986", "organism": "Hamster", "refseq_name": "olfactory receptor 7G2-like", "refseq_ac": [ { "id": "XP_003509158", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509158", "type": "external" } ], "gene_names_uniprotkb": "LOC100767986", "gene_names_refseq": "LOC100767986", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 7G2-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100767986)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614649.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003509158.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJ10-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJ19-1", "uniprot_id": [ { "id": "A0A8C2QJ19_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJ19", "type": "external" } ], "mass": 18733.0, "length": 158, "protein_name": "AP complex subunit sigma", "gene_name": "Ap1s1", "organism": "Hamster", "refseq_name": "AP-1 complex subunit sigma-1A isoform X1", "refseq_ac": [ { "id": "XP_003500984", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500984", "type": "external" } ], "gene_names_uniprotkb": "Ap1s1", "gene_names_refseq": "Ap1s1", "protein_names_uniprotkb": "AP complex subunit sigma", "protein_names_refseq": "AP-1 complex subunit sigma-1A isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100759417)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 130 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613822.1) and transcript sequence (IACG01090769.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003500984.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0035615 clathrin adaptor activity", "go_cellular_component": "GO:0005905 clathrin-coated pit;GO:0043195 terminal bouton;GO:0030121 AP-1 adaptor complex", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0009615 response to virus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJ19-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJ85-1", "uniprot_id": [ { "id": "A0A8C2QJ85_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJ85", "type": "external" } ], "mass": 74717.0, "length": 682, "protein_name": "Acetyl-coenzyme A synthetase", "gene_name": "Acss1", "organism": "Hamster", "refseq_name": "acetyl-coenzyme A synthetase 2-like, mitochondrial isoform X2", "refseq_ac": [ { "id": "XP_027277364", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277364", "type": "external" } ], "gene_names_uniprotkb": "Acss1", "gene_names_refseq": "Acss1", "protein_names_uniprotkb": "Acetyl-coenzyme A synthetase; 6.2.1.1", "protein_names_refseq": "acetyl-coenzyme A synthetase 2-like, mitochondrial isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100769754)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.2.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.1", "type": "external" }, { "id": "6.2.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.17", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016208 AMP binding;GO:0003987 acetate-CoA ligase activity;GO:0050218 propionate-CoA ligase activity", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0019427 acetyl-CoA biosynthetic process from acetate", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJ85-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJ93-1", "uniprot_id": [ { "id": "A0A8C2QJ93_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJ93", "type": "external" } ], "mass": 34497.0, "length": 307, "protein_name": "Ubiquitin recognition factor in ER-associated degradation protein 1", "gene_name": "Ufd1", "organism": "Hamster", "refseq_name": "ubiquitin recognition factor in ER-associated degradation protein 1 isoform X1", "refseq_ac": [ { "id": "XP_027268909", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268909", "type": "external" } ], "gene_names_uniprotkb": "Ufd1", "gene_names_refseq": "Ufd1", "protein_names_uniprotkb": "Ubiquitin recognition factor in ER-associated degradation protein 1; Ubiquitin fusion degradation protein 1 homolog", "protein_names_refseq": "ubiquitin recognition factor in ER-associated degradation protein 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100773227)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures. Acts as a negative regulator of type I interferon production via the complex formed with VCP and NPLOC4, which binds to RIGI and recruits RNF125 to promote ubiquitination and degradation of RIGI., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031593 polyubiquitin modification-dependent protein binding", "go_cellular_component": "GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex;GO:0036501 UFD1-NPL4 complex", "go_biological_process": "GO:0006511 ubiquitin-dependent protein catabolic process;GO:0030970 retrograde protein transport, ER to cytosol", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJ93-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJB1-1", "uniprot_id": [ { "id": "A0A8C2QJB1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJB1", "type": "external" } ], "mass": 40512.0, "length": 367, "protein_name": "Developmentally-regulated GTP-binding protein 1", "gene_name": "Drg1", "organism": "Hamster", "refseq_name": "developmentally-regulated GTP-binding protein 1", "refseq_ac": [ { "id": "XP_027243057", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243057", "type": "external" } ], "gene_names_uniprotkb": "Drg1", "gene_names_refseq": "Drg1", "protein_names_uniprotkb": "Developmentally-regulated GTP-binding protein 1; Neural precursor cell expressed developmentally down-regulated protein 3; Translation factor GTPase DRG1", "protein_names_refseq": "developmentally-regulated GTP-binding protein 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100764489)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0008017 microtubule binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0031116 positive regulation of microtubule polymerization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJB1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJB4-1", "uniprot_id": [ { "id": "A0A8C2QJB4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJB4", "type": "external" } ], "mass": 26621.0, "length": 239, "protein_name": "Lysophospholipase-like protein 1", "gene_name": "Lyplal1", "organism": "Hamster", "refseq_name": "lysophospholipase-like protein 1 isoform X1", "refseq_ac": [ { "id": "XP_003495047", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495047", "type": "external" } ], "gene_names_uniprotkb": "Lyplal1", "gene_names_refseq": "Lyplal1", "protein_names_uniprotkb": "Lysophospholipase-like protein 1; 3.1.2.22", "protein_names_refseq": "lysophospholipase-like protein 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100759088)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 108 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613581.1) and transcript sequence (IACG01059247.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_003495047.1. COMPLETENESS: full length., [RefSeq]; Palmitoyl thioesterase that catalyzes depalmitoylation of CGAS and KCNMA1. Acts as a regulator of innate immunity by mediating depalmitoylation of CGAS, thereby preventing CGAS homodimerization and cyclic GMP-AMP synthase activity. Does not exhibit phospholipase nor triacylglycerol lipase activity, able to hydrolyze only short chain substrates due to its shallow active site., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.2.22", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.22", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "3.1.1.93", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.93", "type": "external" }, { "id": "2.3.1.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.21", "type": "external" }, { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" } ], "go_molecular_function": "GO:0052689 carboxylic ester hydrolase activity;GO:0008474 palmitoyl-(protein) hydrolase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0160049 negative regulation of cGAS/STING signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJB4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJE2-1", "uniprot_id": [ { "id": "A0A8C2QJE2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJE2", "type": "external" } ], "mass": 15772.0, "length": 144, "protein_name": "Interferon-induced transmembrane protein 2", "gene_name": "LOC100756685", "organism": "Hamster", "refseq_name": "interferon-induced transmembrane protein 2", "refseq_ac": [ { "id": "XP_027264820", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264820", "type": "external" } ], "gene_names_uniprotkb": "LOC100756685", "gene_names_refseq": "LOC100756685", "protein_names_uniprotkb": "Interferon-induced transmembrane protein 2", "protein_names_refseq": "interferon-induced transmembrane protein 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756685)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0051607 defense response to virus;GO:0045071 negative regulation of viral genome replication;GO:0060337 type I interferon-mediated signaling pathway;GO:0034341 response to type II interferon;GO:0035455 response to interferon-alpha", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJE2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJF5-1", "uniprot_id": [ { "id": "A0A8C2QJF5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJF5", "type": "external" } ], "mass": 18002.0, "length": 161, "protein_name": "G-protein-signaling modulator 3", "gene_name": "Gpsm3", "organism": "Hamster", "refseq_name": "G-protein-signaling modulator 3 isoform X2", "refseq_ac": [ { "id": "XP_035306546", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306546", "type": "external" } ], "gene_names_uniprotkb": "Gpsm3", "gene_names_refseq": "Gpsm3", "protein_names_uniprotkb": "G-protein-signaling modulator 3", "protein_names_refseq": "G-protein-signaling modulator 3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100766237)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Interacts with subunit of G(i) alpha proteins and regulates the activation of G(i) alpha proteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030695 GTPase regulator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0050729 positive regulation of inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJF5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJH3-1", "uniprot_id": [ { "id": "A0A8C2QJH3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJH3", "type": "external" } ], "mass": 74934.0, "length": 687, "protein_name": "Protein Smaug homolog 2 isoform X2", "gene_name": "Samd4b", "organism": "Hamster", "refseq_name": "protein Smaug homolog 2 isoform X2", "refseq_ac": [ { "id": "XP_027286303", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286303", "type": "external" } ], "gene_names_uniprotkb": "Samd4b", "gene_names_refseq": "Samd4b", "protein_names_uniprotkb": "Protein Smaug homolog 2 isoform X2", "protein_names_refseq": "protein Smaug homolog 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100760986)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0004435 phosphatidylinositol-4,5-bisphosphate phospholipase C activity;GO:0030371 translation repressor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0000932 P-body", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0035556 intracellular signal transduction;GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJH3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJJ3-1", "uniprot_id": [ { "id": "A0A8C2QJJ3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJJ3", "type": "external" } ], "mass": 18802.0, "length": 163, "protein_name": "ADP-ribosylation factor-like protein 2-binding protein", "gene_name": "Arl2bp", "organism": "Hamster", "refseq_name": "ADP-ribosylation factor-like protein 2-binding protein isoform X1", "refseq_ac": [ { "id": "XP_003503674", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503674", "type": "external" } ], "gene_names_uniprotkb": "Arl2bp", "gene_names_refseq": "Arl2bp", "protein_names_uniprotkb": "ADP-ribosylation factor-like protein 2-binding protein; ARF-like 2-binding protein", "protein_names_refseq": "ADP-ribosylation factor-like protein 2-binding protein isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100763207)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 247 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613984.1) and transcript sequence (IACG01059150.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003503674.1. COMPLETENESS: full length., [RefSeq]; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005758 mitochondrial intermembrane space;GO:0005813 centrosome;GO:0030496 midbody;GO:0036064 ciliary basal body", "go_biological_process": "GO:0051457 maintenance of protein location in nucleus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJJ3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJK9-1", "uniprot_id": [ { "id": "A0A8C2QJK9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJK9", "type": "external" } ], "mass": 82365.0, "length": 730, "protein_name": "Conserved oligomeric Golgi complex subunit 2", "gene_name": "Cog2", "organism": "Hamster", "refseq_name": "conserved oligomeric Golgi complex subunit 2 isoform X1", "refseq_ac": [ { "id": "XP_003496865", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496865", "type": "external" } ], "gene_names_uniprotkb": "Cog2", "gene_names_refseq": "Cog2", "protein_names_uniprotkb": "Conserved oligomeric Golgi complex subunit 2; Component of oligomeric Golgi complex 2", "protein_names_refseq": "conserved oligomeric Golgi complex subunit 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100767234)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613636.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005795 Golgi stack;GO:0017119 Golgi transport complex;GO:0016020 membrane", "go_biological_process": "GO:0015031 protein transport;GO:0007030 Golgi organization;GO:0000301 retrograde transport, vesicle recycling within Golgi;GO:0006891 intra-Golgi vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJK9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJL5-1", "uniprot_id": [ { "id": "A0A8C2QJL5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJL5", "type": "external" } ], "mass": 12094.0, "length": 110, "protein_name": "Tumor suppressor candidate 2 isoform X2", "gene_name": "Tusc2", "organism": "Hamster", "refseq_name": "tumor suppressor candidate 2 isoform X1", "refseq_ac": [ { "id": "XP_007639342", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639342", "type": "external" } ], "gene_names_uniprotkb": "Tusc2", "gene_names_refseq": "Tusc2", "protein_names_uniprotkb": "Tumor suppressor candidate 2 isoform X2", "protein_names_refseq": "tumor suppressor candidate 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100770046)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 140 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613788.1) and transcript sequence (IACG01044857.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007639342.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006954 inflammatory response;GO:0051881 regulation of mitochondrial membrane potential", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJL5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJL7-1", "uniprot_id": [ { "id": "A0A8C2QJL7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJL7", "type": "external" } ], "mass": 28693.0, "length": 257, "protein_name": "Tetraspanin", "gene_name": "Upk1a", "organism": "Hamster", "refseq_name": "uroplakin-1a isoform X2", "refseq_ac": [ { "id": "XP_027287045", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287045", "type": "external" } ], "gene_names_uniprotkb": "Upk1a", "gene_names_refseq": "Upk1a", "protein_names_uniprotkb": "Tetraspanin", "protein_names_refseq": "uroplakin-1a isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100750870)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0120001 apical plasma membrane urothelial plaque;GO:0009986 cell surface", "go_biological_process": "GO:0030855 epithelial cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJL7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJM5-1", "uniprot_id": [ { "id": "A0A8C2QJM5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJM5", "type": "external" } ], "mass": 33096.0, "length": 297, "protein_name": "Transmembrane protein 178A", "gene_name": "Tmem178a", "organism": "Hamster", "refseq_name": "transmembrane protein 178A isoform X2", "refseq_ac": [ { "id": "XP_027273694", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273694", "type": "external" } ], "gene_names_uniprotkb": "Tmem178a", "gene_names_refseq": "Tmem178a", "protein_names_uniprotkb": "Transmembrane protein 178A", "protein_names_refseq": "transmembrane protein 178A isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762056)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0051480 regulation of cytosolic calcium ion concentration;GO:0045671 negative regulation of osteoclast differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJM5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJM9-1", "uniprot_id": [ { "id": "A0A8C2QJM9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJM9", "type": "external" } ], "mass": 44761.0, "length": 394, "protein_name": "Actin-related protein 2", "gene_name": "Actr2", "organism": "Hamster", "refseq_name": "actin-related protein 2", "refseq_ac": [ { "id": "XP_027243869", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243869", "type": "external" } ], "gene_names_uniprotkb": "Actr2", "gene_names_refseq": "Actr2", "protein_names_uniprotkb": "Actin-related protein 2", "protein_names_refseq": "actin-related protein 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100752591)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0005524 ATP binding", "go_cellular_component": "GO:0005885 Arp2/3 protein complex", "go_biological_process": "GO:0034314 Arp2/3 complex-mediated actin nucleation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJM9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJR5-1", "uniprot_id": [ { "id": "A0A8C2QJR5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJR5", "type": "external" } ], "mass": 71891.0, "length": 635, "protein_name": "MAGUK p55 subfamily member 4", "gene_name": "Mpp4", "organism": "Hamster", "refseq_name": "MAGUK p55 subfamily member 4", "refseq_ac": [ { "id": "XP_007609913", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007609913", "type": "external" } ], "gene_names_uniprotkb": "Mpp4", "gene_names_refseq": "Mpp4", "protein_names_uniprotkb": "MAGUK p55 subfamily member 4; Discs large homolog 6", "protein_names_refseq": "MAGUK p55 subfamily member 4", "tax_id": 10029, "disease": "", "pathway": " (cge:100766366)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613648.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May play a role in retinal photoreceptors development., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005912 adherens junction", "go_biological_process": "GO:0008104 intracellular protein localization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJR5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJR6-1", "uniprot_id": [ { "id": "A0A8C2QJR6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJR6", "type": "external" } ], "mass": 92454.0, "length": 839, "protein_name": "Amyloid-beta A4 precursor protein-binding family A member 1 isoform X2", "gene_name": "Apba1", "organism": "Hamster", "refseq_name": "amyloid-beta A4 precursor protein-binding family A member 1 isoform X2", "refseq_ac": [ { "id": "XP_027262309", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262309", "type": "external" } ], "gene_names_uniprotkb": "Apba1", "gene_names_refseq": "Apba1", "protein_names_uniprotkb": "Amyloid-beta A4 precursor protein-binding family A member 1 isoform X2", "protein_names_refseq": "amyloid-beta A4 precursor protein-binding family A member 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774931)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0001540 amyloid-beta binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0048787 presynaptic active zone membrane;GO:0005794 Golgi apparatus;GO:0043197 dendritic spine;GO:0098685 Schaffer collateral - CA1 synapse", "go_biological_process": "GO:0015031 protein transport;GO:0007268 chemical synaptic transmission;GO:0099171 presynaptic modulation of chemical synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJR6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJR9-1", "uniprot_id": [ { "id": "A0A8C2QJR9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJR9", "type": "external" } ], "mass": 141986.0, "length": 1244, "protein_name": "Protein MMS22-like", "gene_name": "Mms22l", "organism": "Hamster", "refseq_name": "protein MMS22-like isoform X2", "refseq_ac": [ { "id": "XP_027259247", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259247", "type": "external" } ], "gene_names_uniprotkb": "Mms22l", "gene_names_refseq": "Mms22l", "protein_names_uniprotkb": "Protein MMS22-like; Methyl methanesulfonate-sensitivity protein 22-like", "protein_names_refseq": "protein MMS22-like isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100768068)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the MMS22L-TONSL complex, a complex that promotes homologous recombination-mediated repair of double-strand breaks (DSBs) at stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication. It mediates the assembly of RAD51 filaments on single-stranded DNA (ssDNA): the MMS22L-TONSL complex is recruited to DSBs following histone replacement by histone chaperones and eviction of the replication protein A complex (RPA/RP-A) from DSBs. Following recruitment to DSBs, the TONSL-MMS22L complex promotes recruitment of RAD51 filaments and subsequent homologous recombination. Within the complex, MMS22L acts by binding ssDNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0043596 nuclear replication fork;GO:0035861 site of double-strand break;GO:0035101 FACT complex;GO:0042555 MCM complex", "go_biological_process": "GO:0006325 chromatin organization;GO:0000724 double-strand break repair via homologous recombination;GO:0031297 replication fork processing;GO:0071168 protein localization to chromatin", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJR9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJS9-1", "uniprot_id": [ { "id": "A0A8C2QJS9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJS9", "type": "external" } ], "mass": 44775.0, "length": 399, "protein_name": "Lipase", "gene_name": "LOC100757425", "organism": "Hamster", "refseq_name": "tear acid lipase-like protein isoform X2", "refseq_ac": [ { "id": "XP_027262563", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262563", "type": "external" } ], "gene_names_uniprotkb": "LOC100757425", "gene_names_refseq": "LOC100757425", "protein_names_uniprotkb": "Lipase", "protein_names_refseq": "tear acid lipase-like protein isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100757425)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016788 hydrolase activity, acting on ester bonds", "go_cellular_component": "", "go_biological_process": "GO:0016042 lipid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJS9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJT0-1", "uniprot_id": [ { "id": "A0A8C2QJT0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJT0", "type": "external" } ], "mass": 18203.0, "length": 157, "protein_name": "Protein UXT", "gene_name": "Uxt", "organism": "Hamster", "refseq_name": "protein UXT isoform X1", "refseq_ac": [ { "id": "XP_027288106", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288106", "type": "external" } ], "gene_names_uniprotkb": "Uxt", "gene_names_refseq": "Uxt", "protein_names_uniprotkb": "Protein UXT; Ubiquitously expressed transcript protein", "protein_names_refseq": "protein UXT isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100764181)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0003714 transcription corepressor activity;GO:0048487 beta-tubulin binding", "go_cellular_component": "GO:0000922 spindle pole;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0016592 mediator complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007098 centrosome cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJT0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJT5-1", "uniprot_id": [ { "id": "A0A8C2QJT5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJT5", "type": "external" } ], "mass": 72071.0, "length": 646, "protein_name": "ATP-binding cassette sub-family G member 4 isoform X1", "gene_name": "Abcg4", "organism": "Hamster", "refseq_name": "ATP-binding cassette sub-family G member 4 isoform X1", "refseq_ac": [ { "id": "XP_007650305", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650305", "type": "external" } ], "gene_names_uniprotkb": "Abcg4", "gene_names_refseq": "Abcg4", "protein_names_uniprotkb": "ATP-binding cassette sub-family G member 4 isoform X1", "protein_names_refseq": "ATP-binding cassette sub-family G member 4 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100756677)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615154.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0016887 ATP hydrolysis activity;GO:0034041 ABC-type sterol transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0010008 endosome membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0010875 positive regulation of cholesterol efflux;GO:0006355 regulation of DNA-templated transcription;GO:0033344 cholesterol efflux;GO:0042632 cholesterol homeostasis;GO:0045542 positive regulation of cholesterol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJT5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJU5-1", "uniprot_id": [ { "id": "A0A8C2QJU5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJU5", "type": "external" } ], "mass": 32436.0, "length": 299, "protein_name": "Ankyrin repeat domain-containing protein 54", "gene_name": "Ankrd54", "organism": "Hamster", "refseq_name": "ankyrin repeat domain-containing protein 54 isoform X2", "refseq_ac": [ { "id": "XP_027259781", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259781", "type": "external" } ], "gene_names_uniprotkb": "Ankrd54", "gene_names_refseq": "Ankrd54", "protein_names_uniprotkb": "Ankyrin repeat domain-containing protein 54", "protein_names_refseq": "ankyrin repeat domain-containing protein 54 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756181)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays an important role in regulating intracellular signaling events associated with erythroid terminal differentiation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0044877 protein-containing complex binding;GO:0019887 protein kinase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0030496 midbody", "go_biological_process": "GO:1902531 regulation of intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJU5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QK34-1", "uniprot_id": [ { "id": "A0A8C2QK34_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QK34", "type": "external" } ], "mass": 45923.0, "length": 423, "protein_name": "E3 ubiquitin-protein ligase RNF128 isoform X2", "gene_name": "Rnf128", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase RNF128 isoform X2", "refseq_ac": [ { "id": "XP_027289468", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289468", "type": "external" } ], "gene_names_uniprotkb": "Rnf128", "gene_names_refseq": "Rnf128", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RNF128 isoform X2", "protein_names_refseq": "E3 ubiquitin-protein ligase RNF128 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100761486)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0016020 membrane;GO:0005770 late endosome", "go_biological_process": "GO:0031647 regulation of protein stability", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QK34-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QK54-1", "uniprot_id": [ { "id": "A0A8C2QK54_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QK54", "type": "external" } ], "mass": 60375.0, "length": 540, "protein_name": "Atlastin-3 isoform X2", "gene_name": "Atl3", "organism": "Hamster", "refseq_name": "atlastin-3 isoform X2", "refseq_ac": [ { "id": "XP_027264191", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264191", "type": "external" } ], "gene_names_uniprotkb": "Atl3", "gene_names_refseq": "Atl3", "protein_names_uniprotkb": "Atlastin-3 isoform X2", "protein_names_refseq": "atlastin-3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100752365)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" } ], "go_molecular_function": "GO:0005525 GTP binding;GO:0042802 identical protein binding;GO:0140523 GTPase-dependent fusogenic activity;GO:0003924 GTPase activity", "go_cellular_component": "GO:0098826 endoplasmic reticulum tubular network membrane", "go_biological_process": "GO:0071346 cellular response to type II interferon;GO:1990809 endoplasmic reticulum tubular network membrane organization;GO:0016320 endoplasmic reticulum membrane fusion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QK54-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QK86-1", "uniprot_id": [ { "id": "A0A8C2QK86_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QK86", "type": "external" } ], "mass": 83025.0, "length": 700, "protein_name": "Centrosomal protein of 83 kDa isoform X1", "gene_name": "Cep83", "organism": "Hamster", "refseq_name": "centrosomal protein of 83 kDa isoform X1", "refseq_ac": [ { "id": "XP_003508334", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508334", "type": "external" } ], "gene_names_uniprotkb": "Cep83", "gene_names_refseq": "Cep83", "protein_names_uniprotkb": "Centrosomal protein of 83 kDa isoform X1", "protein_names_refseq": "centrosomal protein of 83 kDa isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100765559)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 250 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614514.1) and transcript sequence (IACG01050298.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005813 centrosome;GO:0005814 centriole;GO:0097539 ciliary transition fiber", "go_biological_process": "GO:0060271 cilium assembly;GO:0048278 vesicle docking;GO:0051660 establishment of centrosome localization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QK86-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QKF4-1", "uniprot_id": [ { "id": "A0A8C2QKF4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QKF4", "type": "external" } ], "mass": 125474.0, "length": 1101, "protein_name": "Transmembrane channel-like protein", "gene_name": "Tmc3", "organism": "Hamster", "refseq_name": "transmembrane channel-like protein 3", "refseq_ac": [ { "id": "XP_027263358", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263358", "type": "external" } ], "gene_names_uniprotkb": "Tmc3", "gene_names_refseq": "Tmc3", "protein_names_uniprotkb": "Transmembrane channel-like protein", "protein_names_refseq": "transmembrane channel-like protein 3", "tax_id": 10029, "disease": "", "pathway": " (cge:100767616)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008381 mechanosensitive monoatomic ion channel activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QKF4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QKF5-1", "uniprot_id": [ { "id": "A0A8C2QKF5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QKF5", "type": "external" } ], "mass": 55869.0, "length": 483, "protein_name": "V-type proton ATPase subunit H", "gene_name": "Atp6v1h", "organism": "Hamster", "refseq_name": "V-type proton ATPase subunit H isoform X1", "refseq_ac": [ { "id": "XP_027254738", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254738", "type": "external" } ], "gene_names_uniprotkb": "Atp6v1h", "gene_names_refseq": "Atp6v1h", "protein_names_uniprotkb": "V-type proton ATPase subunit H", "protein_names_refseq": "V-type proton ATPase subunit H isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100754134)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit H is essential for V-ATPase activity, but not for the assembly of the complex. Involved in the endocytosis mediated by clathrin-coated pits, required for the formation of endosomes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046961 proton-transporting ATPase activity, rotational mechanism", "go_cellular_component": "GO:0005829 cytosol;GO:0005765 lysosomal membrane;GO:0030665 clathrin-coated vesicle membrane;GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain", "go_biological_process": "GO:0006897 endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QKF5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QKP0-1", "uniprot_id": [ { "id": "A0A8C2QKP0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QKP0", "type": "external" } ], "mass": 55232.0, "length": 509, "protein_name": "CCR4-NOT transcription complex subunit 11", "gene_name": "Cnot11", "organism": "Hamster", "refseq_name": "CCR4-NOT transcription complex subunit 11", "refseq_ac": [ { "id": "XP_027242590", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027242590", "type": "external" } ], "gene_names_uniprotkb": "Cnot11", "gene_names_refseq": "Cnot11", "protein_names_uniprotkb": "CCR4-NOT transcription complex subunit 11", "protein_names_refseq": "CCR4-NOT transcription complex subunit 11", "tax_id": 10029, "disease": "", "pathway": " (cge:100760179)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0030014 CCR4-NOT complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0031047 regulatory ncRNA-mediated gene silencing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QKP0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QKS7-1", "uniprot_id": [ { "id": "A0A8C2QKS7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QKS7", "type": "external" } ], "mass": 40576.0, "length": 367, "protein_name": "Proline-rich protein 5-like", "gene_name": "Prr5l", "organism": "Hamster", "refseq_name": "proline-rich protein 5-like", "refseq_ac": [ { "id": "XP_003497506", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497506", "type": "external" } ], "gene_names_uniprotkb": "Prr5l", "gene_names_refseq": "Prr5l", "protein_names_uniprotkb": "Proline-rich protein 5-like", "protein_names_refseq": "proline-rich protein 5-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100753398)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613649.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0031932 TORC2 complex", "go_biological_process": "GO:0010762 regulation of fibroblast migration;GO:0090316 positive regulation of intracellular protein transport;GO:0034599 cellular response to oxidative stress;GO:0061014 positive regulation of mRNA catabolic process;GO:0038203 TORC2 signaling", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QKS7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QKT0-1", "uniprot_id": [ { "id": "A0A8C2QKT0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QKT0", "type": "external" } ], "mass": 26929.0, "length": 233, "protein_name": "Kv channel-interacting protein 4", "gene_name": "LOC100755926", "organism": "Hamster", "refseq_name": "Kv channel-interacting protein 4 isoform X2", "refseq_ac": [ { "id": "XP_027242776", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027242776", "type": "external" } ], "gene_names_uniprotkb": "LOC100755926", "gene_names_refseq": "LOC100755926", "protein_names_uniprotkb": "Kv channel-interacting protein 4", "protein_names_refseq": "Kv channel-interacting protein 4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100755926)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027242776.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015459 potassium channel regulator activity;GO:0005509 calcium ion binding;GO:0005267 potassium channel activity", "go_cellular_component": "GO:0005777 peroxisome;GO:0008076 voltage-gated potassium channel complex", "go_biological_process": "GO:1901379 regulation of potassium ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QKT0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QKW6-1", "uniprot_id": [ { "id": "A0A8C2QKW6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QKW6", "type": "external" } ], "mass": 53615.0, "length": 464, "protein_name": "Gamma-aminobutyric acid receptor subunit gamma-1 isoform X2", "gene_name": "Gabrg1", "organism": "Hamster", "refseq_name": "gamma-aminobutyric acid receptor subunit gamma-1 isoform X2", "refseq_ac": [ { "id": "XP_027246636", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246636", "type": "external" } ], "gene_names_uniprotkb": "Gabrg1", "gene_names_refseq": "Gabrg1", "protein_names_uniprotkb": "Gamma-aminobutyric acid receptor subunit gamma-1 isoform X2", "protein_names_refseq": "gamma-aminobutyric acid receptor subunit gamma-1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756681)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" } ], "go_molecular_function": "GO:0005254 chloride channel activity;GO:0004890 GABA-A receptor activity;GO:0005230 extracellular ligand-gated monoatomic ion channel activity", "go_cellular_component": "GO:0045211 postsynaptic membrane;GO:0034707 chloride channel complex", "go_biological_process": "GO:0007214 gamma-aminobutyric acid signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QKW6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QKX5-1", "uniprot_id": [ { "id": "A0A8C2QKX5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QKX5", "type": "external" } ], "mass": 14174.0, "length": 128, "protein_name": "NHP2-like protein 1", "gene_name": "LOC100771351; LOC100772188", "organism": "Hamster", "refseq_name": "NHP2-like protein 1 isoform X2", "refseq_ac": [ { "id": "XP_027259909", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259909", "type": "external" } ], "gene_names_uniprotkb": "LOC100771351; LOC100772188", "gene_names_refseq": "LOC100771351", "protein_names_uniprotkb": "NHP2-like protein 1", "protein_names_refseq": "NHP2-like protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100771351); (cge:100772188)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Common component of the spliceosome and rRNA processing machinery., [UniProtKB, UniProtKB, UniProtKB]; Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in pre-mRNA splicing as component of the spliceosome. Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly. The protein undergoes a conformational change upon RNA-binding. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) complexes that function in methylation of multiple sites on ribosomal RNAs (rRNAs) and messenger RNAs (mRNAs)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0034512 box C/D sno(s)RNA binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005681 spliceosomal complex;GO:0031428 box C/D methylation guide snoRNP complex;GO:0046540 U4/U6 x U5 tri-snRNP complex", "go_biological_process": "GO:0042254 ribosome biogenesis;GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QKX5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QKY1-1", "uniprot_id": [ { "id": "A0A8C2QKY1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QKY1", "type": "external" } ], "mass": 36563.0, "length": 317, "protein_name": "Protein phosphatase 1 regulatory subunit", "gene_name": "Ppp1r3c", "organism": "Hamster", "refseq_name": "protein phosphatase 1 regulatory subunit 3C isoform X2", "refseq_ac": [ { "id": "XP_027262139", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262139", "type": "external" } ], "gene_names_uniprotkb": "Ppp1r3c", "gene_names_refseq": "Ppp1r3c", "protein_names_uniprotkb": "Protein phosphatase 1 regulatory subunit", "protein_names_refseq": "protein phosphatase 1 regulatory subunit 3C isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100765700)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0008157 protein phosphatase 1 binding;GO:2001069 glycogen binding", "go_cellular_component": "GO:0000164 protein phosphatase type 1 complex;GO:0005829 cytosol", "go_biological_process": "GO:0005978 glycogen biosynthetic process;GO:0005979 regulation of glycogen biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QKY1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QKY8-1", "uniprot_id": [ { "id": "A0A8C2QKY8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QKY8", "type": "external" } ], "mass": 71639.0, "length": 651, "protein_name": "E3 SUMO-protein ligase PIAS1 isoform X4", "gene_name": "Pias1", "organism": "Hamster", "refseq_name": "E3 SUMO-protein ligase PIAS1 isoform X4", "refseq_ac": [ { "id": "XP_027270598", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270598", "type": "external" } ], "gene_names_uniprotkb": "Pias1", "gene_names_refseq": "Pias1", "protein_names_uniprotkb": "E3 SUMO-protein ligase PIAS1 isoform X4", "protein_names_refseq": "E3 SUMO-protein ligase PIAS1 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100757208)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0061665 SUMO ligase activity;GO:0008270 zinc ion binding;GO:0003712 transcription coregulator activity;GO:0016874 ligase activity", "go_cellular_component": "GO:0016607 nuclear speck;GO:0000785 chromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0016925 protein sumoylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QKY8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QKZ2-1", "uniprot_id": [ { "id": "A0A8C2QKZ2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QKZ2", "type": "external" } ], "mass": 115208.0, "length": 1011, "protein_name": "PHD finger protein 20", "gene_name": "Phf20", "organism": "Hamster", "refseq_name": "PHD finger protein 20 isoform X2", "refseq_ac": [ { "id": "XP_027277121", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277121", "type": "external" } ], "gene_names_uniprotkb": "Phf20", "gene_names_refseq": "Phf20", "protein_names_uniprotkb": "PHD finger protein 20", "protein_names_refseq": "PHD finger protein 20 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762872)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0031965 nuclear membrane;GO:0071339 MLL1 complex;GO:0044545 NSL complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QKZ2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QL01-1", "uniprot_id": [ { "id": "A0A8C2QL01_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QL01", "type": "external" } ], "mass": 119102.0, "length": 1029, "protein_name": "Leucine-rich repeat and coiled-coil domain-containing protein 1", "gene_name": "Lrrcc1", "organism": "Hamster", "refseq_name": "leucine-rich repeat and coiled-coil domain-containing protein 1 isoform X4", "refseq_ac": [ { "id": "XP_027254544", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254544", "type": "external" } ], "gene_names_uniprotkb": "Lrrcc1", "gene_names_refseq": "Lrrcc1", "protein_names_uniprotkb": "Leucine-rich repeat and coiled-coil domain-containing protein 1", "protein_names_refseq": "leucine-rich repeat and coiled-coil domain-containing protein 1 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100773971)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Required for the organization of the mitotic spindle. Maintains the structural integrity of centrosomes during mitosis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005814 centriole", "go_biological_process": "GO:0051301 cell division", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QL01-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QL14-1", "uniprot_id": [ { "id": "A0A8C2QL14_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QL14", "type": "external" } ], "mass": 147441.0, "length": 1269, "protein_name": "Regulator of nonsense transcripts 2", "gene_name": "Upf2", "organism": "Hamster", "refseq_name": "regulator of nonsense transcripts 2 isoform X1", "refseq_ac": [ { "id": "XP_007647954", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007647954", "type": "external" } ], "gene_names_uniprotkb": "Upf2", "gene_names_refseq": "Upf2", "protein_names_uniprotkb": "Regulator of nonsense transcripts 2; Up-frameshift suppressor 2 homolog", "protein_names_refseq": "regulator of nonsense transcripts 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100771546)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613621.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC). Recruited by UPF3B associated with the EJC core at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF3B stimulates both ATPase and RNA helicase activities of UPF1. Binds spliced mRNA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0042162 telomeric DNA binding", "go_cellular_component": "GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm;GO:0035145 exon-exon junction complex", "go_biological_process": "GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QL14-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QLA1-1", "uniprot_id": [ { "id": "A0A8C2QLA1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QLA1", "type": "external" } ], "mass": 18982.0, "length": 170, "protein_name": "Thioredoxin domain-containing protein 12", "gene_name": "Txndc12", "organism": "Hamster", "refseq_name": "thioredoxin domain-containing protein 12", "refseq_ac": [ { "id": "XP_003496546", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496546", "type": "external" } ], "gene_names_uniprotkb": "Txndc12", "gene_names_refseq": "Txndc12", "protein_names_uniprotkb": "Thioredoxin domain-containing protein 12; 1.8.4.2", "protein_names_refseq": "thioredoxin domain-containing protein 12", "tax_id": 10029, "disease": "", "pathway": " (cge:100753389)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613624.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Protein-disulfide reductase of the endoplasmic reticulum that promotes disulfide bond formation in client proteins through its thiol-disulfide oxidase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.8.4.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.4.2", "type": "external" }, { "id": "1.8.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.4.-", "type": "external" } ], "go_molecular_function": "GO:0019153 protein-disulfide reductase (glutathione) activity", "go_cellular_component": "GO:0005788 endoplasmic reticulum lumen", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QLA1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QLB9-1", "uniprot_id": [ { "id": "A0A8C2QLB9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QLB9", "type": "external" } ], "mass": 21615.0, "length": 193, "protein_name": "Major intrinsically disordered NOTCH2-binding receptor 1-like", "gene_name": "Minar2", "organism": "Hamster", "refseq_name": "major intrinsically disordered NOTCH2-binding receptor 1-like", "refseq_ac": [ { "id": "XP_027256745", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256745", "type": "external" } ], "gene_names_uniprotkb": "Minar2", "gene_names_refseq": "Minar2", "protein_names_uniprotkb": "Major intrinsically disordered NOTCH2-binding receptor 1-like", "protein_names_refseq": "major intrinsically disordered NOTCH2-binding receptor 1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100772872)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015485 cholesterol binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005765 lysosomal membrane;GO:0032420 stereocilium", "go_biological_process": "GO:0001525 angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QLB9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QLC4-1", "uniprot_id": [ { "id": "A0A8C2QLC4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QLC4", "type": "external" } ], "mass": 45672.0, "length": 418, "protein_name": "Zinc finger protein 362", "gene_name": "Znf362", "organism": "Hamster", "refseq_name": "zinc finger protein 362", "refseq_ac": [ { "id": "XP_003500673", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500673", "type": "external" } ], "gene_names_uniprotkb": "Znf362", "gene_names_refseq": "Znf362", "protein_names_uniprotkb": "Zinc finger protein 362", "protein_names_refseq": "zinc finger protein 362", "tax_id": 10029, "disease": "", "pathway": " (cge:100774569)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 237 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613801.1) and transcript sequence (IACG01052037.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QLC4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QLH3-1", "uniprot_id": [ { "id": "A0A8C2QLH3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QLH3", "type": "external" } ], "mass": 51132.0, "length": 471, "protein_name": "Thymic stromal cotransporter homolog", "gene_name": "Slc46a2", "organism": "Hamster", "refseq_name": "thymic stromal cotransporter homolog", "refseq_ac": [ { "id": "XP_003505558", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505558", "type": "external" } ], "gene_names_uniprotkb": "Slc46a2", "gene_names_refseq": "Slc46a2", "protein_names_uniprotkb": "Thymic stromal cotransporter homolog", "protein_names_refseq": "thymic stromal cotransporter homolog", "tax_id": 10029, "disease": "", "pathway": " (cge:100770552)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614157.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003505558.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0140360 cyclic-GMP-AMP transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0070430 positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway;GO:0140361 cyclic-GMP-AMP transmembrane import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QLH3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QLH5-1", "uniprot_id": [ { "id": "A0A8C2QLH5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QLH5", "type": "external" } ], "mass": 20046.0, "length": 182, "protein_name": "Ran guanine nucleotide release factor", "gene_name": "Rangrf", "organism": "Hamster", "refseq_name": "ran guanine nucleotide release factor isoform X1", "refseq_ac": [ { "id": "XP_003497220", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497220", "type": "external" } ], "gene_names_uniprotkb": "Rangrf", "gene_names_refseq": "Rangrf", "protein_names_uniprotkb": "Ran guanine nucleotide release factor; Ran-binding protein MOG1", "protein_names_refseq": "ran guanine nucleotide release factor isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100760667)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613643.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May regulate the intracellular trafficking of RAN. Promotes guanine nucleotide release from RAN and inhibits binding of new GTP by preventing the binding of the RAN guanine nucleotide exchange factor RCC1. Regulates the levels of GTP-bound RAN in the nucleus, and thereby plays a role in the regulation of RAN-dependent mitotic spindle dynamics. Enhances the expression of SCN5A at the cell membrane in cardiomyocytes., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017080 sodium channel regulator activity;GO:0044325 transmembrane transporter binding;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0060047 heart contraction;GO:0003254 regulation of membrane depolarization;GO:1902305 regulation of sodium ion transmembrane transport;GO:0006606 protein import into nucleus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QLH5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QLP9-1", "uniprot_id": [ { "id": "A0A8C2QLP9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QLP9", "type": "external" } ], "mass": 61137.0, "length": 562, "protein_name": "DDB1- and CUL4-associated factor 10", "gene_name": "Dcaf10", "organism": "Hamster", "refseq_name": "DDB1- and CUL4-associated factor 10 isoform X3", "refseq_ac": [ { "id": "XP_027258975", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258975", "type": "external" } ], "gene_names_uniprotkb": "Dcaf10", "gene_names_refseq": "Dcaf10", "protein_names_uniprotkb": "DDB1- and CUL4-associated factor 10; WD repeat-containing protein 32", "protein_names_refseq": "DDB1- and CUL4-associated factor 10 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100754235)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0080008 Cul4-RING E3 ubiquitin ligase complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QLP9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QLT4-1", "uniprot_id": [ { "id": "A0A8C2QLT4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QLT4", "type": "external" } ], "mass": 98095.0, "length": 864, "protein_name": "Sphingomyelin phosphodiesterase 4 isoform X1", "gene_name": "Smpd4", "organism": "Hamster", "refseq_name": "sphingomyelin phosphodiesterase 4 isoform X1", "refseq_ac": [ { "id": "XP_007641662", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641662", "type": "external" } ], "gene_names_uniprotkb": "Smpd4", "gene_names_refseq": "Smpd4", "protein_names_uniprotkb": "Sphingomyelin phosphodiesterase 4 isoform X1", "protein_names_refseq": "sphingomyelin phosphodiesterase 4 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100753418)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613919.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0050290 sphingomyelin phosphodiesterase D activity", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005783 endoplasmic reticulum;GO:0042383 sarcolemma;GO:0016020 membrane", "go_biological_process": "GO:0046513 ceramide biosynthetic process;GO:0046475 glycerophospholipid catabolic process;GO:0071356 cellular response to tumor necrosis factor;GO:0006685 sphingomyelin catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QLT4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QLT7-1", "uniprot_id": [ { "id": "A0A8C2QLT7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QLT7", "type": "external" } ], "mass": 20128.0, "length": 189, "protein_name": "Leucine repeat adapter protein 25", "gene_name": "Fam89b", "organism": "Hamster", "refseq_name": "leucine repeat adapter protein 25", "refseq_ac": [ { "id": "XP_003513954", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513954", "type": "external" } ], "gene_names_uniprotkb": "Fam89b", "gene_names_refseq": "Fam89b", "protein_names_uniprotkb": "Leucine repeat adapter protein 25", "protein_names_refseq": "leucine repeat adapter protein 25", "tax_id": 10029, "disease": "", "pathway": " (cge:100771743)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616207.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001222 transcription corepressor binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0030027 lamellipodium", "go_biological_process": "GO:0030335 positive regulation of cell migration;GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030010 establishment of cell polarity;GO:0060392 negative regulation of SMAD protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QLT7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QLU2-1", "uniprot_id": [ { "id": "A0A8C2QLU2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QLU2", "type": "external" } ], "mass": 5751.0, "length": 51, "protein_name": "ATP synthase F(1) complex subunit epsilon, mitochondrial", "gene_name": "Atp5f1e", "organism": "Hamster", "refseq_name": "ATP synthase subunit epsilon, mitochondrial isoform X1", "refseq_ac": [ { "id": "XP_027240692", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240692", "type": "external" } ], "gene_names_uniprotkb": "Atp5f1e", "gene_names_refseq": "Atp5f1e", "protein_names_uniprotkb": "ATP synthase F(1) complex subunit epsilon, mitochondrial; ATP synthase F1 subunit epsilon", "protein_names_refseq": "ATP synthase subunit epsilon, mitochondrial isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:103162776)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 266 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613633.1) and transcript sequence (IACG01075428.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Subunit epsilon, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. May be essential for the assembly of F(1) and may play an important role in the incorporation of the hydrophobic subunit c into the F(1)-c oligomer rotor of the mitochondrial ATP synthase complex., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046933 proton-transporting ATP synthase activity, rotational mechanism", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045259 proton-transporting ATP synthase complex", "go_biological_process": "GO:0042776 proton motive force-driven mitochondrial ATP synthesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QLU2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QLU6-1", "uniprot_id": [ { "id": "A0A8C2QLU6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QLU6", "type": "external" } ], "mass": 103516.0, "length": 925, "protein_name": "Periodic tryptophan protein 2 homolog", "gene_name": "Pwp2", "organism": "Hamster", "refseq_name": "periodic tryptophan protein 2 homolog isoform X1", "refseq_ac": [ { "id": "XP_003500633", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500633", "type": "external" } ], "gene_names_uniprotkb": "Pwp2", "gene_names_refseq": "Pwp2", "protein_names_uniprotkb": "Periodic tryptophan protein 2 homolog", "protein_names_refseq": "periodic tryptophan protein 2 homolog isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100762902)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613799.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0034388 Pwp2p-containing subcomplex of 90S preribosome;GO:0032040 small-subunit processome", "go_biological_process": "GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000028 ribosomal small subunit assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QLU6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QLV4-1", "uniprot_id": [ { "id": "A0A8C2QLV4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QLV4", "type": "external" } ], "mass": 15753.0, "length": 147, "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "Rmi2", "organism": "Hamster", "refseq_name": "recQ-mediated genome instability protein 2 isoform X2", "refseq_ac": [ { "id": "XP_027280592", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280592", "type": "external" } ], "gene_names_uniprotkb": "Rmi2", "gene_names_refseq": "Rmi2", "protein_names_uniprotkb": "RecQ-mediated genome instability protein 2", "protein_names_refseq": "recQ-mediated genome instability protein 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100751512)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates. It is required to regulate sister chromatid segregation and to limit DNA crossover. Essential for the stability, localization, and function of BLM, TOP3A, and complexes containing BLM. In the RMI complex, it is required to target BLM to chromatin and stress-induced nuclear foci and mitotic phosphorylation of BLM., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005829 cytosol;GO:0016607 nuclear speck", "go_biological_process": "GO:2000042 negative regulation of double-strand break repair via homologous recombination;GO:0006260 DNA replication;GO:0000724 double-strand break repair via homologous recombination;GO:0033045 regulation of sister chromatid segregation;GO:0071139 resolution of DNA recombination intermediates", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QLV4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QLY5-1", "uniprot_id": [ { "id": "A0A8C2QLY5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QLY5", "type": "external" } ], "mass": 44974.0, "length": 407, "protein_name": "Potassium channel subfamily K member", "gene_name": "Kcnk3", "organism": "Hamster", "refseq_name": "potassium channel subfamily K member 3 isoform X2", "refseq_ac": [ { "id": "XP_027280319", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280319", "type": "external" } ], "gene_names_uniprotkb": "Kcnk3", "gene_names_refseq": "Kcnk3", "protein_names_uniprotkb": "Potassium channel subfamily K member", "protein_names_refseq": "potassium channel subfamily K member 3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100771641)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015271 outward rectifier potassium channel activity;GO:0022841 potassium ion leak channel activity;GO:0046982 protein heterodimerization activity;GO:0044548 S100 protein binding;GO:0005272 sodium channel activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0003029 detection of hypoxic conditions in blood by carotid body chemoreceptor signaling;GO:0030322 stabilization of membrane potential;GO:0071468 cellular response to acidic pH;GO:0099605 regulation of action potential firing rate", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QLY5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QLY8-1", "uniprot_id": [ { "id": "A0A8C2QLY8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QLY8", "type": "external" } ], "mass": 9477.0, "length": 84, "protein_name": "40S ribosomal protein S27", "gene_name": "Rps27l", "organism": "Hamster", "refseq_name": "40S ribosomal protein S27-like isoform X1", "refseq_ac": [ { "id": "XP_007638295", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638295", "type": "external" } ], "gene_names_uniprotkb": "Rps27l", "gene_names_refseq": "Rps27l", "protein_names_uniprotkb": "40S ribosomal protein S27", "protein_names_refseq": "40S ribosomal protein S27-like isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100751142)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 89 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613730.1) and transcript sequence (JI890399.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005829 cytosol;GO:0005840 ribosome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QLY8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QLZ8-1", "uniprot_id": [ { "id": "A0A8C2QLZ8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QLZ8", "type": "external" } ], "mass": 28970.0, "length": 257, "protein_name": "Regulator of G-protein signaling 7-binding protein isoform X1", "gene_name": "Rgs7bp", "organism": "Hamster", "refseq_name": "regulator of G-protein signaling 7-binding protein isoform X1", "refseq_ac": [ { "id": "XP_003509117", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509117", "type": "external" } ], "gene_names_uniprotkb": "Rgs7bp", "gene_names_refseq": "Rgs7bp", "protein_names_uniprotkb": "Regulator of G-protein signaling 7-binding protein isoform X1", "protein_names_refseq": "regulator of G-protein signaling 7-binding protein isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100752948)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614642.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0042734 presynaptic membrane;GO:0098839 postsynaptic density membrane", "go_biological_process": "GO:0009968 negative regulation of signal transduction;GO:0060078 regulation of postsynaptic membrane potential", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QLZ8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QM13-1", "uniprot_id": [ { "id": "A0A8C2QM13_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QM13", "type": "external" } ], "mass": 22064.0, "length": 211, "protein_name": "Musculin", "gene_name": "LOC113833761", "organism": "Hamster", "refseq_name": "musculin", "refseq_ac": [ { "id": "XP_027254502", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254502", "type": "external" } ], "gene_names_uniprotkb": "LOC113833761", "gene_names_refseq": "LOC113833761", "protein_names_uniprotkb": "Musculin", "protein_names_refseq": "musculin", "tax_id": 10029, "disease": "", "pathway": " (cge:113833761)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027254502.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005654 nucleoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0060021 roof of mouth development;GO:0014707 branchiomeric skeletal muscle development;GO:0060539 diaphragm development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QM13-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QM20-1", "uniprot_id": [ { "id": "A0A8C2QM20_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QM20", "type": "external" } ], "mass": 52027.0, "length": 471, "protein_name": "Cleavage and polyadenylation specificity factor subunit 7", "gene_name": "Cpsf7", "organism": "Hamster", "refseq_name": "cleavage and polyadenylation specificity factor subunit 7 isoform X1", "refseq_ac": [ { "id": "XP_027262507", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262507", "type": "external" } ], "gene_names_uniprotkb": "Cpsf7", "gene_names_refseq": "Cpsf7", "protein_names_uniprotkb": "Cleavage and polyadenylation specificity factor subunit 7", "protein_names_refseq": "cleavage and polyadenylation specificity factor subunit 7 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100770766)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs. CPSF7 activates directly the mRNA 3'-processing machinery. Binds to pA signals in RNA substrates., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003676 nucleic acid binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005847 mRNA cleavage and polyadenylation specificity factor complex;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0051290 protein heterotetramerization;GO:0110104 mRNA alternative polyadenylation;GO:0180010 co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway;GO:0006397 mRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QM20-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QM25-1", "uniprot_id": [ { "id": "A0A8C2QM25_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QM25", "type": "external" } ], "mass": 15239.0, "length": 134, "protein_name": "Cytochrome b5", "gene_name": "LOC100774522", "organism": "Hamster", "refseq_name": "cytochrome b5", "refseq_ac": [ { "id": "XP_003512427", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512427", "type": "external" } ], "gene_names_uniprotkb": "LOC100774522", "gene_names_refseq": "LOC100774522", "protein_names_uniprotkb": "Cytochrome b5", "protein_names_refseq": "cytochrome b5", "tax_id": 10029, "disease": "", "pathway": " (cge:100774522)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615437.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019899 enzyme binding;GO:0046872 metal ion binding;GO:0020037 heme binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QM25-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QM34-1", "uniprot_id": [ { "id": "A0A8C2QM34_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QM34", "type": "external" } ], "mass": 43751.0, "length": 402, "protein_name": "Calcium-responsive transactivator isoform X2", "gene_name": "LOC100769060", "organism": "Hamster", "refseq_name": "calcium-responsive transactivator isoform X2", "refseq_ac": [ { "id": "XP_027275673", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275673", "type": "external" } ], "gene_names_uniprotkb": "LOC100769060", "gene_names_refseq": "LOC100769060", "protein_names_uniprotkb": "Calcium-responsive transactivator isoform X2", "protein_names_refseq": "calcium-responsive transactivator isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100769060)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity", "go_cellular_component": "GO:0005654 nucleoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006325 chromatin organization;GO:0050775 positive regulation of dendrite morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QM34-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QM39-1", "uniprot_id": [ { "id": "A0A8C2QM39_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QM39", "type": "external" } ], "mass": 122400.0, "length": 1099, "protein_name": "Guanylate cyclase", "gene_name": "LOC100760728", "organism": "Hamster", "refseq_name": "guanylate cyclase 2G-like isoform X2", "refseq_ac": [ { "id": "XP_035298998", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298998", "type": "external" } ], "gene_names_uniprotkb": "LOC100760728", "gene_names_refseq": "LOC100760728", "protein_names_uniprotkb": "Guanylate cyclase; 4.6.1.2", "protein_names_refseq": "guanylate cyclase 2G-like isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100760728)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.6.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:4.6.1.2", "type": "external" } ], "go_molecular_function": "GO:0004016 adenylate cyclase activity;GO:0004383 guanylate cyclase activity;GO:0004672 protein kinase activity;GO:0005524 ATP binding;GO:0005525 GTP binding", "go_cellular_component": "GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0007168 receptor guanylyl cyclase signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QM39-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QM82-1", "uniprot_id": [ { "id": "A0A8C2QM82_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QM82", "type": "external" } ], "mass": 55801.0, "length": 483, "protein_name": "Septin", "gene_name": "Septin8", "organism": "Hamster", "refseq_name": "septin-8 isoform X5", "refseq_ac": [ { "id": "XP_027283333", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283333", "type": "external" } ], "gene_names_uniprotkb": "Septin8", "gene_names_refseq": "Septin8", "protein_names_uniprotkb": "Septin", "protein_names_refseq": "septin-8 isoform X5", "tax_id": 10029, "disease": "", "pathway": " (cge:100762885)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Filament-forming cytoskeletal GTPase., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005525 GTP binding", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0042995 cell projection", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QM82-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QM88-1", "uniprot_id": [ { "id": "A0A8C2QM88_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QM88", "type": "external" } ], "mass": 43353.0, "length": 379, "protein_name": "Serpin B6", "gene_name": "LOC100762176", "organism": "Hamster", "refseq_name": "serpin B6-like isoform X2", "refseq_ac": [ { "id": "XP_027265081", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265081", "type": "external" } ], "gene_names_uniprotkb": "LOC100762176", "gene_names_refseq": "LOC100762176", "protein_names_uniprotkb": "Serpin B6", "protein_names_refseq": "serpin B6-like isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762176)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QM88-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QMB1-1", "uniprot_id": [ { "id": "A0A8C2QMB1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QMB1", "type": "external" } ], "mass": 54514.0, "length": 480, "protein_name": "AFG1-like ATPase", "gene_name": "Afg1l", "organism": "Hamster", "refseq_name": "AFG1-like ATPase isoform X1", "refseq_ac": [ { "id": "XP_003497030", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497030", "type": "external" } ], "gene_names_uniprotkb": "Afg1l", "gene_names_refseq": "Afg1l", "protein_names_uniprotkb": "AFG1-like ATPase; Lactation elevated protein 1", "protein_names_refseq": "AFG1-like ATPase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100770027)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613639.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Putative mitochondrial ATPase. Plays a role in mitochondrial morphology and mitochondrial protein metabolism. Promotes degradation of excess nuclear-encoded complex IV subunits (COX4I1, COX5A and COX6A1) and normal activity of complexes III and IV of the respiratory chain. Mediates mitochondrial translocation of TP53 and its transcription-independent apoptosis in response to genotoxic stress., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0031966 mitochondrial membrane;GO:0005739 mitochondrion", "go_biological_process": "GO:0035694 mitochondrial protein catabolic process;GO:0141164 mitochondrial protein quality control", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QMB1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QMC5-1", "uniprot_id": [ { "id": "A0A8C2QMC5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QMC5", "type": "external" } ], "mass": 68558.0, "length": 603, "protein_name": "Condensin-2 complex subunit H2", "gene_name": "Ncaph2", "organism": "Hamster", "refseq_name": "condensin-2 complex subunit H2 isoform X2", "refseq_ac": [ { "id": "XP_003509610", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509610", "type": "external" } ], "gene_names_uniprotkb": "Ncaph2", "gene_names_refseq": "Ncaph2", "protein_names_uniprotkb": "Condensin-2 complex subunit H2; Non-SMC condensin II complex subunit H2", "protein_names_refseq": "condensin-2 complex subunit H2 isoform X2", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614727.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000796 condensin complex", "go_biological_process": "GO:0051306 mitotic sister chromatid separation;GO:0010032 meiotic chromosome condensation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QMC5-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QMC9-1", "uniprot_id": [ { "id": "A0A8C2QMC9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QMC9", "type": "external" } ], "mass": 29212.0, "length": 248, "protein_name": "Large ribosomal subunit protein uL30", "gene_name": "Rpl7", "organism": "Hamster", "refseq_name": "60S ribosomal protein L7", "refseq_ac": [ { "id": "XP_027254616", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254616", "type": "external" } ], "gene_names_uniprotkb": "Rpl7", "gene_names_refseq": "Rpl7", "protein_names_uniprotkb": "Large ribosomal subunit protein uL30; 60S ribosomal protein L7", "protein_names_refseq": "60S ribosomal protein L7", "tax_id": 10029, "disease": "", "pathway": " (cge:100763698)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0045202 synapse;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation;GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QMC9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QMD8-1", "uniprot_id": [ { "id": "A0A8C2QMD8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QMD8", "type": "external" } ], "mass": 91880.0, "length": 814, "protein_name": "Sodium/hydrogen exchanger", "gene_name": "Slc9a2", "organism": "Hamster", "refseq_name": "sodium/hydrogen exchanger 2", "refseq_ac": [ { "id": "XP_003499846", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499846", "type": "external" } ], "gene_names_uniprotkb": "Slc9a2", "gene_names_refseq": "Slc9a2", "protein_names_uniprotkb": "Sodium/hydrogen exchanger", "protein_names_refseq": "sodium/hydrogen exchanger 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100757298)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613754.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015385 sodium:proton antiporter activity;GO:0015386 potassium:proton antiporter activity", "go_cellular_component": "GO:0030054 cell junction;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0030855 epithelial cell differentiation;GO:0051453 regulation of intracellular pH;GO:0098719 sodium ion import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QMD8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QME9-1", "uniprot_id": [ { "id": "A0A8C2QME9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QME9", "type": "external" } ], "mass": 64149.0, "length": 600, "protein_name": "Transcription factor 7-like 1 isoform X2", "gene_name": "Tcf7l1", "organism": "Hamster", "refseq_name": "transcription factor 7-like 1 isoform X2", "refseq_ac": [ { "id": "XP_027285263", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285263", "type": "external" } ], "gene_names_uniprotkb": "Tcf7l1", "gene_names_refseq": "Tcf7l1", "protein_names_uniprotkb": "Transcription factor 7-like 1 isoform X2", "protein_names_refseq": "transcription factor 7-like 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100753225)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0008013 beta-catenin binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0000785 chromatin;GO:1990907 beta-catenin-TCF complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0043588 skin development;GO:0060070 canonical Wnt signaling pathway;GO:0035019 somatic stem cell population maintenance;GO:0009888 tissue development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QME9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QMH5-1", "uniprot_id": [ { "id": "A0A8C2QMH5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QMH5", "type": "external" } ], "mass": 44952.0, "length": 415, "protein_name": "Arrestin domain-containing protein 4", "gene_name": "Arrdc4", "organism": "Hamster", "refseq_name": "arrestin domain-containing protein 4", "refseq_ac": [ { "id": "XP_003504244", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504244", "type": "external" } ], "gene_names_uniprotkb": "Arrdc4", "gene_names_refseq": "Arrdc4", "protein_names_uniprotkb": "Arrestin domain-containing protein 4", "protein_names_refseq": "arrestin domain-containing protein 4", "tax_id": 10029, "disease": "", "pathway": " (cge:100770261)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614042.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:1990756 ubiquitin-like ligase-substrate adaptor activity", "go_cellular_component": "GO:0005769 early endosome;GO:0005886 plasma membrane;GO:1903561 extracellular vesicle", "go_biological_process": "GO:0015031 protein transport;GO:0070534 protein K63-linked ubiquitination;GO:0032728 positive regulation of interferon-beta production;GO:0140112 extracellular vesicle biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QMH5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QMI3-1", "uniprot_id": [ { "id": "A0A8C2QMI3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QMI3", "type": "external" } ], "mass": 27942.0, "length": 252, "protein_name": "Homeobox protein MOX-1", "gene_name": "Meox1", "organism": "Hamster", "refseq_name": "homeobox protein MOX-1 isoform X2", "refseq_ac": [ { "id": "XP_027283737", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283737", "type": "external" } ], "gene_names_uniprotkb": "Meox1", "gene_names_refseq": "Meox1", "protein_names_uniprotkb": "Homeobox protein MOX-1; Mesenchyme homeobox 1", "protein_names_refseq": "homeobox protein MOX-1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100760789)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints. Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0071837 HMG box domain binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0061056 sclerotome development;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0061053 somite development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QMI3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QMJ1-1", "uniprot_id": [ { "id": "A0A8C2QMJ1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QMJ1", "type": "external" } ], "mass": 66809.0, "length": 580, "protein_name": "Zinc finger protein 354A", "gene_name": "LOC100759975", "organism": "Hamster", "refseq_name": "zinc finger protein 354A isoform X1", "refseq_ac": [ { "id": "XP_016826577", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016826577", "type": "external" } ], "gene_names_uniprotkb": "LOC100759975", "gene_names_refseq": "LOC100759975", "protein_names_uniprotkb": "Zinc finger protein 354A; Kidney, ischemia, and developmentally-regulated protein 1; Renal transcription factor Kid-1; Transcription factor 17", "protein_names_refseq": "zinc finger protein 354A isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100759975)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613693.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; It may play a role in renal development and may also be involved in the repair of the kidney after ischemia-reperfusion or folic acid administration., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QMJ1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QML3-1", "uniprot_id": [ { "id": "A0A8C2QML3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QML3", "type": "external" } ], "mass": 96431.0, "length": 859, "protein_name": "Villin-like protein isoform X2", "gene_name": "Vill", "organism": "Hamster", "refseq_name": "villin-like protein isoform X2", "refseq_ac": [ { "id": "XP_027271152", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271152", "type": "external" } ], "gene_names_uniprotkb": "Vill", "gene_names_refseq": "Vill", "protein_names_uniprotkb": "Villin-like protein isoform X2", "protein_names_refseq": "villin-like protein isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100751215)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0015629 actin cytoskeleton", "go_biological_process": "GO:0051016 barbed-end actin filament capping;GO:0008154 actin polymerization or depolymerization;GO:0051014 actin filament severing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QML3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QMM5-1", "uniprot_id": [ { "id": "A0A8C2QMM5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QMM5", "type": "external" } ], "mass": 125296.0, "length": 1134, "protein_name": "Protocadherin-18 isoform X2", "gene_name": "Pcdh18", "organism": "Hamster", "refseq_name": "protocadherin-18 isoform X2", "refseq_ac": [ { "id": "XP_003509406", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509406", "type": "external" } ], "gene_names_uniprotkb": "Pcdh18", "gene_names_refseq": "Pcdh18", "protein_names_uniprotkb": "Protocadherin-18 isoform X2", "protein_names_refseq": "protocadherin-18 isoform X2", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614695.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Potential calcium-dependent cell-adhesion protein., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007420 brain development;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QMM5-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QMR6-1", "uniprot_id": [ { "id": "A0A8C2QMR6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QMR6", "type": "external" } ], "mass": 67578.0, "length": 609, "protein_name": "Polyadenylate-binding protein", "gene_name": "Pabpc1l", "organism": "Hamster", "refseq_name": "polyadenylate-binding protein 1-like", "refseq_ac": [ { "id": "XP_027279279", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279279", "type": "external" } ], "gene_names_uniprotkb": "Pabpc1l", "gene_names_refseq": "Pabpc1l", "protein_names_uniprotkb": "Polyadenylate-binding protein; PABP", "protein_names_refseq": "polyadenylate-binding protein 1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100762044)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Binds the poly(A) tail of mRNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0010628 positive regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QMR6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QMW1-1", "uniprot_id": [ { "id": "A0A8C2QMW1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QMW1", "type": "external" } ], "mass": 20374.0, "length": 179, "protein_name": "Mesencephalic astrocyte-derived neurotrophic factor isoform X2", "gene_name": "Manf", "organism": "Hamster", "refseq_name": "mesencephalic astrocyte-derived neurotrophic factor isoform X1", "refseq_ac": [ { "id": "XP_007639280", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639280", "type": "external" } ], "gene_names_uniprotkb": "Manf", "gene_names_refseq": "Manf", "protein_names_uniprotkb": "Mesencephalic astrocyte-derived neurotrophic factor isoform X2", "protein_names_refseq": "mesencephalic astrocyte-derived neurotrophic factor isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100768617)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 128 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613788.1) and transcript sequence (IACG01095576.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008083 growth factor activity;GO:0120146 sulfatide binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005788 endoplasmic reticulum lumen", "go_biological_process": "GO:0031175 neuron projection development;GO:0036500 ATF6-mediated unfolded protein response;GO:0071542 dopaminergic neuron differentiation;GO:1905897 regulation of response to endoplasmic reticulum stress", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QMW1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QMX3-1", "uniprot_id": [ { "id": "A0A8C2QMX3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QMX3", "type": "external" } ], "mass": 43703.0, "length": 386, "protein_name": "Vacuolar protein-sorting-associated protein 36", "gene_name": "Vps36", "organism": "Hamster", "refseq_name": "vacuolar protein-sorting-associated protein 36 isoform X1", "refseq_ac": [ { "id": "XP_003503352", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503352", "type": "external" } ], "gene_names_uniprotkb": "Vps36", "gene_names_refseq": "Vps36", "protein_names_uniprotkb": "Vacuolar protein-sorting-associated protein 36; ESCRT-II complex subunit VPS36", "protein_names_refseq": "vacuolar protein-sorting-associated protein 36 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100772258)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 134 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613958.1) and transcript sequence (JI879327.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003503352.1. COMPLETENESS: full length., [RefSeq]; Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0032266 phosphatidylinositol-3-phosphate binding;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0000814 ESCRT II complex;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005764 lysosome;GO:0031902 late endosome membrane", "go_biological_process": "GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QMX3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QMY5-1", "uniprot_id": [ { "id": "A0A8C2QMY5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QMY5", "type": "external" } ], "mass": 30302.0, "length": 270, "protein_name": "Sorting nexin-11", "gene_name": "Snx11", "organism": "Hamster", "refseq_name": "sorting nexin-11", "refseq_ac": [ { "id": "XP_007638513", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638513", "type": "external" } ], "gene_names_uniprotkb": "Snx11", "gene_names_refseq": "Snx11", "protein_names_uniprotkb": "Sorting nexin-11", "protein_names_refseq": "sorting nexin-11", "tax_id": 10029, "disease": "", "pathway": " (cge:100751542)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613745.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:1901981 phosphatidylinositol phosphate binding", "go_cellular_component": "GO:0005768 endosome;GO:0005886 plasma membrane", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0016050 vesicle organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QMY5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QN10-1", "uniprot_id": [ { "id": "A0A8C2QN10_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QN10", "type": "external" } ], "mass": 25594.0, "length": 222, "protein_name": "STING ER exit protein", "gene_name": "CXHXorf56", "organism": "Hamster", "refseq_name": "UPF0428 protein CXorf56 homolog isoform X1", "refseq_ac": [ { "id": "XP_003500078", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500078", "type": "external" } ], "gene_names_uniprotkb": "CXHXorf56", "gene_names_refseq": "CXHXorf56", "protein_names_uniprotkb": "STING ER exit protein", "protein_names_refseq": "UPF0428 protein CXorf56 homolog isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100768804)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 178 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613768.1) and transcript sequence (JI874455.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003500078.1. COMPLETENESS: full length., [RefSeq]; Molecular adapter that stimulates membrane curvature formation and subsequent endoplasmic reticulum exit site (ERES) establishment by recruiting PI3K complex I, leading to COPII vesicle-mediated transport. Promotes endoplasmic reticulum (ER) exit of cGAMP-activated STING1 oligomers., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005789 endoplasmic reticulum membrane;GO:0044297 cell body", "go_biological_process": "GO:0090158 endoplasmic reticulum membrane organization;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0032527 protein exit from endoplasmic reticulum", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QN10-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QN47-1", "uniprot_id": [ { "id": "A0A8C2QN47_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QN47", "type": "external" } ], "mass": 60266.0, "length": 546, "protein_name": "Oncoprotein-induced transcript 3 protein", "gene_name": "Oit3", "organism": "Hamster", "refseq_name": "oncoprotein-induced transcript 3 protein", "refseq_ac": [ { "id": "XP_027244129", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244129", "type": "external" } ], "gene_names_uniprotkb": "Oit3", "gene_names_refseq": "Oit3", "protein_names_uniprotkb": "Oncoprotein-induced transcript 3 protein; Liver-specific zona pellucida domain-containing protein", "protein_names_refseq": "oncoprotein-induced transcript 3 protein", "tax_id": 10029, "disease": "", "pathway": " (cge:100758658)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in hepatocellular function and development., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005635 nuclear envelope", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QN47-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QN48-1", "uniprot_id": [ { "id": "A0A8C2QN48_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QN48", "type": "external" } ], "mass": 78725.0, "length": 768, "protein_name": "POU domain protein", "gene_name": "Pou2f1", "organism": "Hamster", "refseq_name": "POU domain, class 2, transcription factor 1 isoform X4", "refseq_ac": [ { "id": "XP_027272917", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272917", "type": "external" } ], "gene_names_uniprotkb": "Pou2f1", "gene_names_refseq": "Pou2f1", "protein_names_uniprotkb": "POU domain protein", "protein_names_refseq": "POU domain, class 2, transcription factor 1 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100767850)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QN48-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QN72-1", "uniprot_id": [ { "id": "A0A8C2QN72_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QN72", "type": "external" } ], "mass": 72813.0, "length": 663, "protein_name": "tRNA (guanine(26)-N(2))-dimethyltransferase", "gene_name": "Trmt1", "organism": "Hamster", "refseq_name": "tRNA (guanine(26)-N(2))-dimethyltransferase isoform X2", "refseq_ac": [ { "id": "XP_003501973", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501973", "type": "external" } ], "gene_names_uniprotkb": "Trmt1", "gene_names_refseq": "Trmt1", "protein_names_uniprotkb": "tRNA (guanine(26)-N(2))-dimethyltransferase; 2.1.1.216", "protein_names_refseq": "tRNA (guanine(26)-N(2))-dimethyltransferase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100765046)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613865.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.216", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.216", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000049 tRNA binding;GO:0160104 tRNA (guanine(26)-N2)-dimethyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion", "go_biological_process": "GO:0002940 tRNA N2-guanine methylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QN72-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QN80-1", "uniprot_id": [ { "id": "A0A8C2QN80_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QN80", "type": "external" } ], "mass": 28608.0, "length": 247, "protein_name": "Acidic leucine-rich nuclear phosphoprotein 32 family member", "gene_name": "Anp32a", "organism": "Hamster", "refseq_name": "acidic leucine-rich nuclear phosphoprotein 32 family member A isoform X2", "refseq_ac": [ { "id": "XP_027270611", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270611", "type": "external" } ], "gene_names_uniprotkb": "Anp32a", "gene_names_refseq": "Anp32a", "protein_names_uniprotkb": "Acidic leucine-rich nuclear phosphoprotein 32 family member", "protein_names_refseq": "acidic leucine-rich nuclear phosphoprotein 32 family member A isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100758072)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Multifunctional protein that is involved in the regulation of many processes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042393 histone binding", "go_cellular_component": "GO:0048471 perinuclear region of cytoplasm;GO:0016363 nuclear matrix", "go_biological_process": "GO:0006913 nucleocytoplasmic transport;GO:0042981 regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QN80-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QN83-1", "uniprot_id": [ { "id": "A0A8C2QN83_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QN83", "type": "external" } ], "mass": 24920.0, "length": 216, "protein_name": "Fibroblast growth factor", "gene_name": "Fgf17", "organism": "Hamster", "refseq_name": "fibroblast growth factor 17 isoform X1", "refseq_ac": [ { "id": "XP_003496203", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496203", "type": "external" } ], "gene_names_uniprotkb": "Fgf17", "gene_names_refseq": "Fgf17", "protein_names_uniprotkb": "Fibroblast growth factor; FGF", "protein_names_refseq": "fibroblast growth factor 17 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100764611)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613613.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005105 type 1 fibroblast growth factor receptor binding;GO:0008083 growth factor activity;GO:0005111 type 2 fibroblast growth factor receptor binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QN83-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QN91-1", "uniprot_id": [ { "id": "A0A8C2QN91_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QN91", "type": "external" } ], "mass": 31426.0, "length": 295, "protein_name": "Protein shisa-2 homolog isoform X2", "gene_name": "Shisa2", "organism": "Hamster", "refseq_name": "protein shisa-2 homolog isoform X2", "refseq_ac": [ { "id": "XP_027246221", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246221", "type": "external" } ], "gene_names_uniprotkb": "Shisa2", "gene_names_refseq": "Shisa2", "protein_names_uniprotkb": "Protein shisa-2 homolog isoform X2", "protein_names_refseq": "protein shisa-2 homolog isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767261)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0030178 negative regulation of Wnt signaling pathway;GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QN91-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QN94-1", "uniprot_id": [ { "id": "A0A8C2QN94_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QN94", "type": "external" } ], "mass": 17810.0, "length": 164, "protein_name": "Protein phosphatase 1 regulatory subunit 14", "gene_name": "LOC103161642", "organism": "Hamster", "refseq_name": "protein phosphatase 1 regulatory subunit 14C", "refseq_ac": [ { "id": "XP_027256792", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256792", "type": "external" } ], "gene_names_uniprotkb": "LOC103161642", "gene_names_refseq": "LOC103161642", "protein_names_uniprotkb": "Protein phosphatase 1 regulatory subunit 14", "protein_names_refseq": "protein phosphatase 1 regulatory subunit 14C", "tax_id": 10029, "disease": "", "pathway": " (cge:103161642)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Inhibitor of PPP1CA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004865 protein serine/threonine phosphatase inhibitor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QN94-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QNA2-1", "uniprot_id": [ { "id": "A0A8C2QNA2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QNA2", "type": "external" } ], "mass": 104113.0, "length": 943, "protein_name": "DDB1- and CUL4-associated factor 5", "gene_name": "Dcaf5", "organism": "Hamster", "refseq_name": "DDB1- and CUL4-associated factor 5 isoform X3", "refseq_ac": [ { "id": "XP_027274199", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274199", "type": "external" } ], "gene_names_uniprotkb": "Dcaf5", "gene_names_refseq": "Dcaf5", "protein_names_uniprotkb": "DDB1- and CUL4-associated factor 5; WD repeat-containing protein 22", "protein_names_refseq": "DDB1- and CUL4-associated factor 5 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100765902)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0080008 Cul4-RING E3 ubiquitin ligase complex", "go_biological_process": "GO:0045717 negative regulation of fatty acid biosynthetic process;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QNA2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QNB7-1", "uniprot_id": [ { "id": "A0A8C2QNB7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QNB7", "type": "external" } ], "mass": 60657.0, "length": 538, "protein_name": "Growth factor receptor-bound protein 14", "gene_name": "Grb14", "organism": "Hamster", "refseq_name": "growth factor receptor-bound protein 14 isoform X2", "refseq_ac": [ { "id": "XP_027276108", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276108", "type": "external" } ], "gene_names_uniprotkb": "Grb14", "gene_names_refseq": "Grb14", "protein_names_uniprotkb": "Growth factor receptor-bound protein 14; GRB14 adapter protein", "protein_names_refseq": "growth factor receptor-bound protein 14 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100752932)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0030971 receptor tyrosine kinase binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0010008 endosome membrane", "go_biological_process": "GO:0046627 negative regulation of insulin receptor signaling pathway;GO:0008286 insulin receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QNB7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QNC2-1", "uniprot_id": [ { "id": "A0A8C2QNC2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QNC2", "type": "external" } ], "mass": 52807.0, "length": 480, "protein_name": "Cytochrome b-c1 complex subunit 1, mitochondrial", "gene_name": "LOC100766805", "organism": "Hamster", "refseq_name": "cytochrome b-c1 complex subunit 1, mitochondrial isoform X1", "refseq_ac": [ { "id": "XP_007642967", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642967", "type": "external" } ], "gene_names_uniprotkb": "LOC100766805", "gene_names_refseq": "LOC100766805", "protein_names_uniprotkb": "Cytochrome b-c1 complex subunit 1, mitochondrial; Complex III subunit 1; Core protein I; Ubiquinol-cytochrome-c reductase complex core protein 1", "protein_names_refseq": "cytochrome b-c1 complex subunit 1, mitochondrial isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100766805)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 247 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614047.1) and transcript sequence (IACG01087900.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007642967.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045275 respiratory chain complex III", "go_biological_process": "GO:0022904 respiratory electron transport chain", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QNC2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QNC5-1", "uniprot_id": [ { "id": "A0A8C2QNC5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QNC5", "type": "external" } ], "mass": 91216.0, "length": 833, "protein_name": "Transcription regulator protein BACH2 isoform X2", "gene_name": "Bach2", "organism": "Hamster", "refseq_name": "transcription regulator protein BACH2 isoform X2", "refseq_ac": [ { "id": "XP_035294876", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294876", "type": "external" } ], "gene_names_uniprotkb": "Bach2", "gene_names_refseq": "Bach2", "protein_names_uniprotkb": "Transcription regulator protein BACH2 isoform X2", "protein_names_refseq": "transcription regulator protein BACH2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774050)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0090721 primary adaptive immune response involving T cells and B cells", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QNC5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QNC8-1", "uniprot_id": [ { "id": "A0A8C2QNC8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QNC8", "type": "external" } ], "mass": 47377.0, "length": 422, "protein_name": "Leucine-rich repeat protein 1", "gene_name": "Lrr1", "organism": "Hamster", "refseq_name": "leucine-rich repeat protein 1 isoform X1", "refseq_ac": [ { "id": "XP_027273944", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273944", "type": "external" } ], "gene_names_uniprotkb": "Lrr1", "gene_names_refseq": "Lrr1", "protein_names_uniprotkb": "Leucine-rich repeat protein 1", "protein_names_refseq": "leucine-rich repeat protein 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100752788)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Substrate recognition subunit of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. ECS(LRR1) ubiquitinates MCM7 and promotes CMG replisome disassembly by VCP and chromatin extraction during S-phase. May negatively regulate the 4-1BB-mediated signaling cascades which result in the activation of NK-kappaB and JNK1., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QNC8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QND4-1", "uniprot_id": [ { "id": "A0A8C2QND4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QND4", "type": "external" } ], "mass": 110538.0, "length": 1001, "protein_name": "ubiquitinyl hydrolase 1", "gene_name": "Usp36", "organism": "Hamster", "refseq_name": "ubiquitin carboxyl-terminal hydrolase 36 isoform X2", "refseq_ac": [ { "id": "XP_035303299", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303299", "type": "external" } ], "gene_names_uniprotkb": "Usp36", "gene_names_refseq": "Usp36", "protein_names_uniprotkb": "ubiquitinyl hydrolase 1; 3.4.19.12", "protein_names_refseq": "ubiquitin carboxyl-terminal hydrolase 36 isoform X2", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0006508 proteolysis;GO:0016579 protein deubiquitination;GO:0042981 regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QND4-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QNM0-1", "uniprot_id": [ { "id": "A0A8C2QNM0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QNM0", "type": "external" } ], "mass": 23157.0, "length": 212, "protein_name": "Clathrin light chain", "gene_name": "Cltb", "organism": "Hamster", "refseq_name": "clathrin light chain B isoform X1", "refseq_ac": [ { "id": "XP_027264064", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264064", "type": "external" } ], "gene_names_uniprotkb": "Cltb", "gene_names_refseq": "Cltb", "protein_names_uniprotkb": "Clathrin light chain", "protein_names_refseq": "clathrin light chain B isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100767928)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 311 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613681.1) and transcript sequence (IACG01057686.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027264064.1. COMPLETENESS: full length., [RefSeq]; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005198 structural molecule activity;GO:0032050 clathrin heavy chain binding", "go_cellular_component": "GO:0030672 synaptic vesicle membrane;GO:0030130 clathrin coat of trans-Golgi network vesicle;GO:0030132 clathrin coat of coated pit;GO:0099631 postsynaptic endocytic zone cytoplasmic component", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0072583 clathrin-dependent endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QNM0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QNQ9-1", "uniprot_id": [ { "id": "A0A8C2QNQ9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QNQ9", "type": "external" } ], "mass": 45016.0, "length": 428, "protein_name": "Monocarboxylate transporter 13", "gene_name": "Slc16a13", "organism": "Hamster", "refseq_name": "monocarboxylate transporter 13 isoform X2", "refseq_ac": [ { "id": "XP_027282747", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282747", "type": "external" } ], "gene_names_uniprotkb": "Slc16a13", "gene_names_refseq": "Slc16a13", "protein_names_uniprotkb": "Monocarboxylate transporter 13; Solute carrier family 16 member 13", "protein_names_refseq": "monocarboxylate transporter 13 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763738)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015293 symporter activity;GO:0008028 monocarboxylic acid transmembrane transporter activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QNQ9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QNS0-1", "uniprot_id": [ { "id": "A0A8C2QNS0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QNS0", "type": "external" } ], "mass": 46618.0, "length": 426, "protein_name": "Probable imidazolonepropionase", "gene_name": "Amdhd1", "organism": "Hamster", "refseq_name": "probable imidazolonepropionase", "refseq_ac": [ { "id": "XP_003501466", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501466", "type": "external" } ], "gene_names_uniprotkb": "Amdhd1", "gene_names_refseq": "Amdhd1", "protein_names_uniprotkb": "Probable imidazolonepropionase; 3.5.2.7; Amidohydrolase domain-containing protein 1", "protein_names_refseq": "probable imidazolonepropionase", "tax_id": 10029, "disease": "", "pathway": " (cge:100754101)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613849.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003501466.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.5.2.7", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.2.7", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0050480 imidazolonepropionase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0019556 L-histidine catabolic process to glutamate and formamide;GO:0019557 L-histidine catabolic process to glutamate and formate", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QNS0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QNS7-1", "uniprot_id": [ { "id": "A0A8C2QNS7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QNS7", "type": "external" } ], "mass": 24151.0, "length": 219, "protein_name": "Tetratricopeptide repeat protein 9A", "gene_name": "Ttc9", "organism": "Hamster", "refseq_name": "tetratricopeptide repeat protein 9A isoform X2", "refseq_ac": [ { "id": "XP_027274224", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274224", "type": "external" } ], "gene_names_uniprotkb": "Ttc9", "gene_names_refseq": "Ttc9", "protein_names_uniprotkb": "Tetratricopeptide repeat protein 9A", "protein_names_refseq": "tetratricopeptide repeat protein 9A isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763223)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0044183 protein folding chaperone", "go_cellular_component": "GO:0005740 mitochondrial envelope;GO:0005829 cytosol;GO:0016020 membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0043066 negative regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QNS7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QNU3-1", "uniprot_id": [ { "id": "A0A8C2QNU3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QNU3", "type": "external" } ], "mass": 63640.0, "length": 557, "protein_name": "MARVEL domain-containing protein 2", "gene_name": "Marveld2", "organism": "Hamster", "refseq_name": "MARVEL domain-containing protein 2", "refseq_ac": [ { "id": "XP_035295023", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295023", "type": "external" } ], "gene_names_uniprotkb": "Marveld2", "gene_names_refseq": "Marveld2", "protein_names_uniprotkb": "MARVEL domain-containing protein 2", "protein_names_refseq": "MARVEL domain-containing protein 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100773152)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005923 bicellular tight junction;GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane;GO:0031410 cytoplasmic vesicle;GO:0043220 Schmidt-Lanterman incisure", "go_biological_process": "GO:0061028 establishment of endothelial barrier;GO:0070830 bicellular tight junction assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QNU3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QNV3-1", "uniprot_id": [ { "id": "A0A8C2QNV3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QNV3", "type": "external" } ], "mass": 59895.0, "length": 527, "protein_name": "UDP-glucuronosyltransferase", "gene_name": "LOC100762963", "organism": "Hamster", "refseq_name": "UDP-glucuronosyltransferase 2A1 isoform X3", "refseq_ac": [ { "id": "XP_027245055", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245055", "type": "external" } ], "gene_names_uniprotkb": "LOC100762963", "gene_names_refseq": "LOC100762963", "protein_names_uniprotkb": "UDP-glucuronosyltransferase; 2.4.1.17", "protein_names_refseq": "UDP-glucuronosyltransferase 2A1 isoform X3", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.17", "type": "external" } ], "go_molecular_function": "GO:0015020 glucuronosyltransferase activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0006805 xenobiotic metabolic process;GO:0008206 bile acid metabolic process;GO:0007606 sensory perception of chemical stimulus;GO:0009608 response to symbiont", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QNV3-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QNW5-1", "uniprot_id": [ { "id": "A0A8C2QNW5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QNW5", "type": "external" } ], "mass": 61937.0, "length": 537, "protein_name": "Zinc finger protein 397 isoform X1", "gene_name": "Znf397", "organism": "Hamster", "refseq_name": "zinc finger protein 397 isoform X1", "refseq_ac": [ { "id": "XP_035296139", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035296139", "type": "external" } ], "gene_names_uniprotkb": "Znf397", "gene_names_refseq": "Znf397", "protein_names_uniprotkb": "Zinc finger protein 397 isoform X1", "protein_names_refseq": "zinc finger protein 397 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100763007)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QNW5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QNX5-1", "uniprot_id": [ { "id": "A0A8C2QNX5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QNX5", "type": "external" } ], "mass": 21888.0, "length": 209, "protein_name": "Mitochondrial import inner membrane translocase subunit TIM23", "gene_name": "LOC100768872", "organism": "Hamster", "refseq_name": "mitochondrial import inner membrane translocase subunit Tim23", "refseq_ac": [ { "id": "XP_003495353", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495353", "type": "external" } ], "gene_names_uniprotkb": "LOC100768872", "gene_names_refseq": "LOC100768872", "protein_names_uniprotkb": "Mitochondrial import inner membrane translocase subunit TIM23", "protein_names_refseq": "mitochondrial import inner membrane translocase subunit Tim23", "tax_id": 10029, "disease": "", "pathway": " (cge:100768872)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613589.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has a role in the activation of stress-induced mitophagy by protecting PINK1 from OMA1-mediated degradation and facilitating its accumulation at the outer mitochondrial membrane in response to depolarization., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008320 protein transmembrane transporter activity", "go_cellular_component": "GO:0005744 TIM23 mitochondrial import inner membrane translocase complex", "go_biological_process": "GO:0030150 protein import into mitochondrial matrix", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QNX5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QNY0-1", "uniprot_id": [ { "id": "A0A8C2QNY0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QNY0", "type": "external" } ], "mass": 145401.0, "length": 1292, "protein_name": "Zinc finger protein 423", "gene_name": "Znf423", "organism": "Hamster", "refseq_name": "zinc finger protein 423 isoform X3", "refseq_ac": [ { "id": "XP_027261321", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261321", "type": "external" } ], "gene_names_uniprotkb": "Znf423", "gene_names_refseq": "Znf423", "protein_names_uniprotkb": "Zinc finger protein 423; Olf1/EBF-associated zinc finger protein; Smad- and Olf-interacting zinc finger protein", "protein_names_refseq": "zinc finger protein 423 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100756719)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027261321.1. COMPLETENESS: full length., [RefSeq]; Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation; this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007399 nervous system development;GO:0030154 cell differentiation;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QNY0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QNY4-1", "uniprot_id": [ { "id": "A0A8C2QNY4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QNY4", "type": "external" } ], "mass": 43438.0, "length": 383, "protein_name": "tRNA N(3)-cytidine methyltransferase", "gene_name": "Mettl2a", "organism": "Hamster", "refseq_name": "tRNA N(3)-methylcytidine methyltransferase METTL2A isoform X1", "refseq_ac": [ { "id": "XP_003503028", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503028", "type": "external" } ], "gene_names_uniprotkb": "Mettl2a", "gene_names_refseq": "Mettl2a", "protein_names_uniprotkb": "tRNA N(3)-cytidine methyltransferase; 2.1.1.-", "protein_names_refseq": "tRNA N(3)-methylcytidine methyltransferase METTL2A isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100752016)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 140 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613926.1) and transcript sequence (IACG01087297.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003503028.1. COMPLETENESS: full length., [RefSeq]; S-adenosyl-L-methionine-dependent methyltransferase., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" } ], "go_molecular_function": "GO:0052735 tRNA (cytidine-3-)-methyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0030488 tRNA methylation;GO:0008033 tRNA processing;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QNY4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QP42-1", "uniprot_id": [ { "id": "A0A8C2QP42_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QP42", "type": "external" } ], "mass": 64885.0, "length": 597, "protein_name": "Sodium/mannose cotransporter SLC5A10", "gene_name": "Slc5a10", "organism": "Hamster", "refseq_name": "sodium/glucose cotransporter 5 isoform X4", "refseq_ac": [ { "id": "XP_027283035", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283035", "type": "external" } ], "gene_names_uniprotkb": "Slc5a10", "gene_names_refseq": "Slc5a10", "protein_names_uniprotkb": "Sodium/mannose cotransporter SLC5A10; Sodium/glucose cotransporter 5; Solute carrier family 5 member 10", "protein_names_refseq": "sodium/glucose cotransporter 5 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100750825)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Electrogenic Na+-coupled sugar symporter that actively transports D-mannose or D-fructose at the plasma membrane, with a Na+ to sugar coupling ratio of 1:1. Transporter activity is driven by a transmembrane Na+ electrochemical gradient set by the Na+/K+ pump. Exclusively recognizes sugar substrates having a pyranose ring with an axial hydroxyl group on carbon 2. Has likely evolved to enable renal reabsorption of D-mannose, an important constituent of oligosaccharide chains of glycoproteins. Contributes to dietary D-fructose reabsorption from glomerular filtrate across the brush border of the kidney., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005412 D-glucose:sodium symporter activity;GO:0140929 mannose:sodium symporter activity;GO:0140930 fructose:sodium symporter activity", "go_cellular_component": "GO:0016324 apical plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QP42-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QP51-1", "uniprot_id": [ { "id": "A0A8C2QP51_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QP51", "type": "external" } ], "mass": 35765.0, "length": 317, "protein_name": "UAP56-interacting factor", "gene_name": "Fyttd1", "organism": "Hamster", "refseq_name": "UAP56-interacting factor isoform X1", "refseq_ac": [ { "id": "XP_007638906", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638906", "type": "external" } ], "gene_names_uniprotkb": "Fyttd1", "gene_names_refseq": "Fyttd1", "protein_names_uniprotkb": "UAP56-interacting factor; Forty-two-three domain-containing protein 1", "protein_names_refseq": "UAP56-interacting factor isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100763912)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 248 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613591.1) and transcript sequence (IACG01090147.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0016607 nuclear speck", "go_biological_process": "GO:0006406 mRNA export from nucleus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QP51-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QP69-1", "uniprot_id": [ { "id": "A0A8C2QP69_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QP69", "type": "external" } ], "mass": 35278.0, "length": 325, "protein_name": "Peroxisomal reductase activating PPAR-gamma", "gene_name": "Dhrs7b", "organism": "Hamster", "refseq_name": "dehydrogenase/reductase SDR family member 7B isoform X1", "refseq_ac": [ { "id": "XP_007647372", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007647372", "type": "external" } ], "gene_names_uniprotkb": "Dhrs7b", "gene_names_refseq": "Dhrs7b", "protein_names_uniprotkb": "Peroxisomal reductase activating PPAR-gamma; 1.1.1.101; Dehydrogenase/reductase SDR family member 7B; Short-chain dehydrogenase/reductase family 32C member 1", "protein_names_refseq": "dehydrogenase/reductase SDR family member 7B isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100773373)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613619.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Reductase required for adipogenesis and activation of PPARG nuclear receptor. Can convert acyl and alkyl dihydroxyacetone-phosphate (DHAP) into glycerolipids and ether lipids, respectively, synthesizing ether-linked phospholipids that act as agonists for PPARG. Also regulates adipogenesis by preventing adipocyte browning: following import into the nucleus, interacts with PRDM16, inhibiting the interaction between PRDM16 and PPARG and preventing differentiation of brown adipocytes., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.1.101", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.101", "type": "external" } ], "go_molecular_function": "GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QP69-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QP71-1", "uniprot_id": [ { "id": "A0A8C2QP71_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QP71", "type": "external" } ], "mass": 32076.0, "length": 291, "protein_name": "Protein ILRUN", "gene_name": "Ilrun", "organism": "Hamster", "refseq_name": "protein ILRUN isoform X2", "refseq_ac": [ { "id": "XP_027244815", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244815", "type": "external" } ], "gene_names_uniprotkb": "Ilrun", "gene_names_refseq": "Ilrun", "protein_names_uniprotkb": "Protein ILRUN", "protein_names_refseq": "protein ILRUN isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:107979433)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Negative regulator of innate antiviral response. Blocks IRF3-dependent cytokine production such as IFNA, IFNB and TNF. Interacts with IRF3 and inhibits IRF3 recruitment to type I IFN promoter sequences while also reducing nuclear levels of the coactivators EP300 and CREBBP., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000407 phagophore assembly site", "go_biological_process": "GO:0045087 innate immune response;GO:0016236 macroautophagy", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QP71-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QP90-1", "uniprot_id": [ { "id": "A0A8C2QP90_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QP90", "type": "external" } ], "mass": 81182.0, "length": 694, "protein_name": "G-protein coupled receptor-associated protein LMBRD2 isoform X1", "gene_name": "Lmbrd2", "organism": "Hamster", "refseq_name": "G-protein coupled receptor-associated protein LMBRD2 isoform X1", "refseq_ac": [ { "id": "XP_003515079", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003515079", "type": "external" } ], "gene_names_uniprotkb": "Lmbrd2", "gene_names_refseq": "Lmbrd2", "protein_names_uniprotkb": "G-protein coupled receptor-associated protein LMBRD2 isoform X1", "protein_names_refseq": "G-protein coupled receptor-associated protein LMBRD2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100754477)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003617258.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0071875 adrenergic receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QP90-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QPC3-1", "uniprot_id": [ { "id": "A0A8C2QPC3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QPC3", "type": "external" } ], "mass": 107226.0, "length": 991, "protein_name": "Regulatory solute carrier protein family 1 member 1 isoform X2", "gene_name": "LOC100753562", "organism": "Hamster", "refseq_name": "regulatory solute carrier protein family 1 member 1 isoform X1", "refseq_ac": [ { "id": "XP_016835710", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016835710", "type": "external" } ], "gene_names_uniprotkb": "LOC100753562", "gene_names_refseq": "LOC100753562", "protein_names_uniprotkb": "Regulatory solute carrier protein family 1 member 1 isoform X2", "protein_names_refseq": "regulatory solute carrier protein family 1 member 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100753562)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 225 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615153.1) and transcript sequence (IACG01022445.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_016835710.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004190 aspartic-type endopeptidase activity", "go_cellular_component": "", "go_biological_process": "GO:0015031 protein transport;GO:0031647 regulation of protein stability;GO:0097752 regulation of DNA stability;GO:0051603 proteolysis involved in protein catabolic process;GO:0072711 cellular response to hydroxyurea", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QPC3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QPD9-1", "uniprot_id": [ { "id": "A0A8C2QPD9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QPD9", "type": "external" } ], "mass": 77262.0, "length": 715, "protein_name": "Nucleolin", "gene_name": "Ncl", "organism": "Hamster", "refseq_name": "nucleolin isoform X2", "refseq_ac": [ { "id": "XP_027253249", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253249", "type": "external" } ], "gene_names_uniprotkb": "Ncl", "gene_names_refseq": "Ncl", "protein_names_uniprotkb": "Nucleolin; Protein C23", "protein_names_refseq": "nucleolin isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100689056)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats., [UniProtKB, UniProtKB]", "predicted_glycosites": 8, "predicted_n_glycosites": 0, "predicted_o_glycosites": 8, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003729 mRNA binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm", "go_biological_process": "GO:0051252 regulation of RNA metabolic process;GO:0010557 positive regulation of macromolecule biosynthetic process;GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QPD9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QPG2-1", "uniprot_id": [ { "id": "A0A8C2QPG2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QPG2", "type": "external" } ], "mass": 50295.0, "length": 445, "protein_name": "KICSTOR subunit 2", "gene_name": "C1H12orf66", "organism": "Hamster", "refseq_name": "KICSTOR complex protein C12orf66 homolog isoform X2", "refseq_ac": [ { "id": "XP_027248096", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248096", "type": "external" } ], "gene_names_uniprotkb": "C1H12orf66", "gene_names_refseq": "C1H12orf66", "protein_names_uniprotkb": "KICSTOR subunit 2", "protein_names_refseq": "KICSTOR complex protein C12orf66 homolog isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100757589)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027248096.1. COMPLETENESS: full length., [RefSeq]; As part of the KICSTOR complex functions in the amino acid-sensing branch of the TORC1 signaling pathway. Recruits, in an amino acid-independent manner, the GATOR1 complex to the lysosomal membranes and allows its interaction with GATOR2 and the RAG GTPases. Functions upstream of the RAG GTPases and is required to negatively regulate mTORC1 signaling in absence of amino acids. In absence of the KICSTOR complex mTORC1 is constitutively localized to the lysosome and activated. The KICSTOR complex is also probably involved in the regulation of mTORC1 by glucose., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0140007 KICSTOR complex;GO:0005765 lysosomal membrane", "go_biological_process": "GO:0042149 cellular response to glucose starvation;GO:0034198 cellular response to amino acid starvation;GO:1904262 negative regulation of TORC1 signaling;GO:0061462 protein localization to lysosome", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QPG2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QPG7-1", "uniprot_id": [ { "id": "A0A8C2QPG7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QPG7", "type": "external" } ], "mass": 46891.0, "length": 426, "protein_name": "Actin-like protein 6B", "gene_name": "Actl6b", "organism": "Hamster", "refseq_name": "actin-like protein 6B isoform X2", "refseq_ac": [ { "id": "XP_027272040", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272040", "type": "external" } ], "gene_names_uniprotkb": "Actl6b", "gene_names_refseq": "Actl6b", "protein_names_uniprotkb": "Actin-like protein 6B; BRG1-associated factor 53B", "protein_names_refseq": "actin-like protein 6B isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100753067)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016514 SWI/SNF complex;GO:0071565 nBAF complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0016358 dendrite development;GO:0042551 neuron maturation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QPG7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QPH2-1", "uniprot_id": [ { "id": "A0A8C2QPH2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QPH2", "type": "external" } ], "mass": 74840.0, "length": 674, "protein_name": "XK-related protein", "gene_name": "Xkr5", "organism": "Hamster", "refseq_name": "XK-related protein 5", "refseq_ac": [ { "id": "XP_027245458", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245458", "type": "external" } ], "gene_names_uniprotkb": "Xkr5", "gene_names_refseq": "Xkr5", "protein_names_uniprotkb": "XK-related protein", "protein_names_refseq": "XK-related protein 5", "tax_id": 10029, "disease": "", "pathway": " (cge:100755956)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027245458.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QPH2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QPH7-1", "uniprot_id": [ { "id": "A0A8C2QPH7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QPH7", "type": "external" } ], "mass": 137382.0, "length": 1288, "protein_name": "Activating transcription factor 7-interacting protein 1 isoform X1", "gene_name": "Atf7ip", "organism": "Hamster", "refseq_name": "activating transcription factor 7-interacting protein 1 isoform X1", "refseq_ac": [ { "id": "XP_007643169", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643169", "type": "external" } ], "gene_names_uniprotkb": "Atf7ip", "gene_names_refseq": "Atf7ip", "protein_names_uniprotkb": "Activating transcription factor 7-interacting protein 1 isoform X1", "protein_names_refseq": "activating transcription factor 7-interacting protein 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100753637)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614062.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003714 transcription corepressor activity;GO:0016887 ATP hydrolysis activity;GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0016604 nuclear body;GO:0005667 transcription regulator complex;GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription;GO:0006346 DNA methylation-dependent constitutive heterochromatin formation;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QPH7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QPI9-1", "uniprot_id": [ { "id": "A0A8C2QPI9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QPI9", "type": "external" } ], "mass": 104625.0, "length": 968, "protein_name": "Leucine-rich repeat-containing G-protein coupled receptor 6 isoform X2", "gene_name": "Lgr6", "organism": "Hamster", "refseq_name": "leucine-rich repeat-containing G-protein coupled receptor 6 isoform X2", "refseq_ac": [ { "id": "XP_027273335", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273335", "type": "external" } ], "gene_names_uniprotkb": "Lgr6", "gene_names_refseq": "Lgr6", "protein_names_uniprotkb": "Leucine-rich repeat-containing G-protein coupled receptor 6 isoform X2", "protein_names_refseq": "leucine-rich repeat-containing G-protein coupled receptor 6 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762015)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016500 protein-hormone receptor activity;GO:0008528 G protein-coupled peptide receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0031982 vesicle", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0008283 cell population proliferation;GO:0030335 positive regulation of cell migration;GO:0009755 hormone-mediated signaling pathway;GO:0030177 positive regulation of Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QPI9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QPJ1-1", "uniprot_id": [ { "id": "A0A8C2QPJ1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QPJ1", "type": "external" } ], "mass": 46207.0, "length": 411, "protein_name": "BRO1 domain-containing protein BROX", "gene_name": "Brox", "organism": "Hamster", "refseq_name": "BRO1 domain-containing protein BROX", "refseq_ac": [ { "id": "XP_003495014", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495014", "type": "external" } ], "gene_names_uniprotkb": "Brox", "gene_names_refseq": "Brox", "protein_names_uniprotkb": "BRO1 domain-containing protein BROX; BRO1 domain- and CAAX motif-containing protein", "protein_names_refseq": "BRO1 domain-containing protein BROX", "tax_id": 10029, "disease": "", "pathway": " (cge:100772686)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 317 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613581.1) and transcript sequence (IACG01000555.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Nuclear envelope-associated factor that is involved in the nuclear envelope ruptures during interphase (NERDI) repair, where it is locally recruited by CHMP5 and reduces cytoskeletal stress through its action on SYN2 to help reseal the ruptured membrane., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0031965 nuclear membrane", "go_biological_process": "GO:0007084 mitotic nuclear membrane reassembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QPJ1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QPL9-1", "uniprot_id": [ { "id": "A0A8C2QPL9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QPL9", "type": "external" } ], "mass": 18440.0, "length": 154, "protein_name": "AP complex subunit sigma", "gene_name": "Ap1s3", "organism": "Hamster", "refseq_name": "AP-1 complex subunit sigma-3", "refseq_ac": [ { "id": "XP_027240406", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240406", "type": "external" } ], "gene_names_uniprotkb": "Ap1s3", "gene_names_refseq": "Ap1s3", "protein_names_uniprotkb": "AP complex subunit sigma", "protein_names_refseq": "AP-1 complex subunit sigma-3", "tax_id": 10029, "disease": "", "pathway": " (cge:100764202)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615515.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0035615 clathrin adaptor activity", "go_cellular_component": "GO:0005905 clathrin-coated pit;GO:0030121 AP-1 adaptor complex", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006605 protein targeting", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QPL9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QPM5-1", "uniprot_id": [ { "id": "A0A8C2QPM5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QPM5", "type": "external" } ], "mass": 31715.0, "length": 302, "protein_name": "Homeobox protein", "gene_name": "LOC100752159", "organism": "Hamster", "refseq_name": "pituitary homeobox 3", "refseq_ac": [ { "id": "XP_035297681", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297681", "type": "external" } ], "gene_names_uniprotkb": "LOC100752159", "gene_names_refseq": "LOC100752159", "protein_names_uniprotkb": "Homeobox protein", "protein_names_refseq": "pituitary homeobox 3", "tax_id": 10029, "disease": "", "pathway": " (cge:100752159)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0002089 lens morphogenesis in camera-type eye;GO:0071542 dopaminergic neuron differentiation;GO:0070306 lens fiber cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QPM5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F105-1", "uniprot_id": [ { "id": "A0A9J7F105_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F105", "type": "external" } ], "mass": 115969.0, "length": 1071, "protein_name": "Zinc finger MIZ domain-containing protein 1 isoform X5", "gene_name": "Zmiz1", "organism": "Hamster", "refseq_name": "zinc finger MIZ domain-containing protein 1 isoform X5", "refseq_ac": [ { "id": "XP_027244877", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244877", "type": "external" } ], "gene_names_uniprotkb": "Zmiz1", "gene_names_refseq": "Zmiz1", "protein_names_uniprotkb": "Zinc finger MIZ domain-containing protein 1 isoform X5", "protein_names_refseq": "zinc finger MIZ domain-containing protein 1 isoform X5", "tax_id": 10029, "disease": "", "pathway": " (cge:100754403)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0061665 SUMO ligase activity;GO:0003713 transcription coactivator activity;GO:0008270 zinc ion binding;GO:0046332 SMAD binding;GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0000785 chromatin;GO:0005634 nucleus", "go_biological_process": "GO:0016925 protein sumoylation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0045747 positive regulation of Notch signaling pathway;GO:0060395 SMAD protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F105-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7EVL2-1", "uniprot_id": [ { "id": "A0A9J7EVL2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7EVL2", "type": "external" } ], "mass": 40197.0, "length": 355, "protein_name": "Calcium uniporter protein", "gene_name": "Mcu", "organism": "Hamster", "refseq_name": "calcium uniporter protein, mitochondrial isoform X3", "refseq_ac": [ { "id": "XP_027244126", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244126", "type": "external" } ], "gene_names_uniprotkb": "Mcu", "gene_names_refseq": "Mcu", "protein_names_uniprotkb": "Calcium uniporter protein", "protein_names_refseq": "calcium uniporter protein, mitochondrial isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100762628)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005262 calcium channel activity;GO:0015292 uniporter activity", "go_cellular_component": "GO:1990246 uniplex complex", "go_biological_process": "GO:0019722 calcium-mediated signaling;GO:0032024 positive regulation of insulin secretion;GO:0043065 positive regulation of apoptotic process;GO:0051259 protein complex oligomerization;GO:0042593 glucose homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7EVL2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7EYJ7-1", "uniprot_id": [ { "id": "A0A9J7EYJ7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7EYJ7", "type": "external" } ], "mass": 177732.0, "length": 1555, "protein_name": "UDP-glucose:glycoprotein glucosyltransferase 1", "gene_name": "Uggt1", "organism": "Hamster", "refseq_name": "UDP-glucose:glycoprotein glucosyltransferase 1 isoform X2", "refseq_ac": [ { "id": "XP_027242683", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027242683", "type": "external" } ], "gene_names_uniprotkb": "Uggt1", "gene_names_refseq": "Uggt1", "protein_names_uniprotkb": "UDP-glucose:glycoprotein glucosyltransferase 1; UDP--Glc:glycoprotein glucosyltransferase; UDP-glucose ceramide glucosyltransferase-like 1", "protein_names_refseq": "UDP-glucose:glycoprotein glucosyltransferase 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100773968)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051082 unfolded protein binding;GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity", "go_cellular_component": "GO:0005788 endoplasmic reticulum lumen;GO:0032991 protein-containing complex", "go_biological_process": "GO:0009101 glycoprotein biosynthetic process;GO:0036503 ERAD pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7EYJ7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7EZM5-1", "uniprot_id": [ { "id": "A0A9J7EZM5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7EZM5", "type": "external" } ], "mass": 57249.0, "length": 515, "protein_name": "EGF-containing fibulin-like extracellular matrix protein 1", "gene_name": "Efemp1", "organism": "Hamster", "refseq_name": "EGF-containing fibulin-like extracellular matrix protein 1 isoform X1", "refseq_ac": [ { "id": "XP_003511729", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511729", "type": "external" } ], "gene_names_uniprotkb": "Efemp1", "gene_names_refseq": "Efemp1", "protein_names_uniprotkb": "EGF-containing fibulin-like extracellular matrix protein 1; Fibulin-3", "protein_names_refseq": "EGF-containing fibulin-like extracellular matrix protein 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100750809)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 659 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615198.1) and transcript sequence (JP060013.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003511729.1. COMPLETENESS: full length., [RefSeq]; Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0005154 epidermal growth factor receptor binding;GO:0008083 growth factor activity;GO:0005006 epidermal growth factor receptor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005739 mitochondrion;GO:0031012 extracellular matrix", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0048048 embryonic eye morphogenesis;GO:0032331 negative regulation of chondrocyte differentiation;GO:0048050 post-embryonic eye morphogenesis;GO:0043010 camera-type eye development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7EZM5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F427-1", "uniprot_id": [ { "id": "A0A9J7F427_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F427", "type": "external" } ], "mass": 74273.0, "length": 647, "protein_name": "Peroxisomal carnitine O-octanoyltransferase", "gene_name": "Crot", "organism": "Hamster", "refseq_name": "peroxisomal carnitine O-octanoyltransferase isoform X1", "refseq_ac": [ { "id": "XP_027247341", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247341", "type": "external" } ], "gene_names_uniprotkb": "Crot", "gene_names_refseq": "Crot", "protein_names_uniprotkb": "Peroxisomal carnitine O-octanoyltransferase; 2.3.1.137", "protein_names_refseq": "peroxisomal carnitine O-octanoyltransferase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100750995)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Beta-oxidation of fatty acids. The highest activity concerns the C6 to C10 chain length substrate., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.137", "type": "external" }, { "id": "2.3.1.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.21", "type": "external" }, { "id": "2.3.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.7", "type": "external" } ], "go_molecular_function": "GO:0008458 carnitine O-octanoyltransferase activity", "go_cellular_component": "GO:0005777 peroxisome", "go_biological_process": "GO:0006091 generation of precursor metabolites and energy;GO:0006635 fatty acid beta-oxidation;GO:0051791 medium-chain fatty acid metabolic process;GO:0015908 fatty acid transport;GO:0015936 coenzyme A metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F427-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7EZL2-1", "uniprot_id": [ { "id": "A0A9J7EZL2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7EZL2", "type": "external" } ], "mass": 111685.0, "length": 1009, "protein_name": "Disintegrin and metalloproteinase domain-containing protein 22 isoform X13", "gene_name": "Adam22", "organism": "Hamster", "refseq_name": "disintegrin and metalloproteinase domain-containing protein 22 isoform X13", "refseq_ac": [ { "id": "XP_027247353", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247353", "type": "external" } ], "gene_names_uniprotkb": "Adam22", "gene_names_refseq": "Adam22", "protein_names_uniprotkb": "Disintegrin and metalloproteinase domain-containing protein 22 isoform X13", "protein_names_refseq": "disintegrin and metalloproteinase domain-containing protein 22 isoform X13", "tax_id": 10029, "disease": "", "pathway": " (cge:100751750)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0030424 axon;GO:0012505 endomembrane system;GO:0098839 postsynaptic density membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0099645 neurotransmitter receptor localization to postsynaptic specialization membrane", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7EZL2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F085-1", "uniprot_id": [ { "id": "A0A9J7F085_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F085", "type": "external" } ], "mass": 214147.0, "length": 1865, "protein_name": "Proteasome activator complex subunit 4", "gene_name": "Psme4", "organism": "Hamster", "refseq_name": "proteasome activator complex subunit 4 isoform X2", "refseq_ac": [ { "id": "XP_027243490", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243490", "type": "external" } ], "gene_names_uniprotkb": "Psme4", "gene_names_refseq": "Psme4", "protein_names_uniprotkb": "Proteasome activator complex subunit 4; Proteasome activator PA200; Protein BLM10 homolog", "protein_names_refseq": "proteasome activator complex subunit 4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100773419)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP- and ubiquitin-independent degradation of core histones during spermatogenesis and DNA damage response. Recognizes and binds acetylated histones via its bromodomain-like (BRDL) region and activates the proteasome by opening the gated channel for substrate entry. Binds to the core proteasome via its C-terminus, which occupies the same binding sites as the proteasomal ATPases, opening the closed structure of the proteasome via an active gating mechanism. Component of the spermatoproteasome, a form of the proteasome specifically found in testis: binds to acetylated histones and promotes degradation of histones, thereby participating actively to the exchange of histones during spermatogenesis. Also involved in DNA damage response in somatic cells, by promoting degradation of histones following DNA double-strand breaks., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016504 peptidase activator activity;GO:0070628 proteasome binding", "go_cellular_component": "GO:1990111 spermatoproteasome complex;GO:0005829 cytosol;GO:0016607 nuclear speck", "go_biological_process": "GO:0006281 DNA repair;GO:0010499 proteasomal ubiquitin-independent protein catabolic process;GO:0035092 sperm DNA condensation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F085-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7EWY4-1", "uniprot_id": [ { "id": "A0A9J7EWY4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7EWY4", "type": "external" } ], "mass": 171533.0, "length": 1549, "protein_name": "Nischarin", "gene_name": "Nisch", "organism": "Hamster", "refseq_name": "nischarin isoform X4", "refseq_ac": [ { "id": "XP_027245335", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245335", "type": "external" } ], "gene_names_uniprotkb": "Nisch", "gene_names_refseq": "Nisch", "protein_names_uniprotkb": "Nischarin; Imidazoline receptor 1; Imidazoline-1 receptor", "protein_names_refseq": "nischarin isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100754172)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027245335.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0035091 phosphatidylinositol binding", "go_cellular_component": "GO:0005769 early endosome;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0055037 recycling endosome", "go_biological_process": "GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7EWY4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F416-1", "uniprot_id": [ { "id": "A0A9J7F416_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F416", "type": "external" } ], "mass": 48472.0, "length": 408, "protein_name": "Luc7-like protein", "gene_name": "LOC100767953", "organism": "Hamster", "refseq_name": "putative RNA-binding protein Luc7-like 2 isoform X1", "refseq_ac": [ { "id": "XP_027247284", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247284", "type": "external" } ], "gene_names_uniprotkb": "LOC100767953", "gene_names_refseq": "LOC100767953", "protein_names_uniprotkb": "Luc7-like protein", "protein_names_refseq": "putative RNA-binding protein Luc7-like 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100767953)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Binds cAMP regulatory element DNA sequence. Plays a role in RNA splicing., [UniProtKB, UniProtKB]; Binds to RNA via its Arg/Ser-rich domain., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005685 U1 snRNP;GO:0016607 nuclear speck", "go_biological_process": "GO:0006376 mRNA splice site recognition", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F416-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7EY24-1", "uniprot_id": [ { "id": "A0A9J7EY24_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7EY24", "type": "external" } ], "mass": 520798.0, "length": 4581, "protein_name": "Sacsin", "gene_name": "Sacs", "organism": "Hamster", "refseq_name": "sacsin isoform X1", "refseq_ac": [ { "id": "XP_007639447", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639447", "type": "external" } ], "gene_names_uniprotkb": "Sacs", "gene_names_refseq": "Sacs", "protein_names_uniprotkb": "Sacsin; DnaJ homolog subfamily C member 29", "protein_names_refseq": "sacsin isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100765225)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 328 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613797.1) and transcript sequence (IACG01056109.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007639447.1. COMPLETENESS: full length., [RefSeq]; Co-chaperone which acts as a regulator of the Hsp70 chaperone machinery and may be involved in the processing of other ataxia-linked proteins., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030544 Hsp70 protein binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7EY24-1", "record_type": "protein", "filter_code": "0000000.0000101.000100.000000000010000000.0000000001000.001.00000", "kg_view_protein": true } ]